CN108057179A - The radiotherapy multi-angle imaging device of radiationless hurtless measure - Google Patents
The radiotherapy multi-angle imaging device of radiationless hurtless measure Download PDFInfo
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- CN108057179A CN108057179A CN201711415122.7A CN201711415122A CN108057179A CN 108057179 A CN108057179 A CN 108057179A CN 201711415122 A CN201711415122 A CN 201711415122A CN 108057179 A CN108057179 A CN 108057179A
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- radiotherapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/103—Treatment planning systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Apparatus For Radiation Diagnosis (AREA)
Abstract
The invention discloses a kind of radiotherapy multi-angle imaging devices of radiationless hurtless measure, and including the detector that is connected with X-ray emission device, the detector includes being packaged in shell for gathering the CCD of Cherenkov's photon, and filter plate is additionally provided on CCD.The detector is packaged in front of the KV grade X-rays bulb of X-ray emission device, orthogonal with MV grades of heads；At least 180 ° of the rotatable irradiation of MV grade heads of the X-ray emission device, CCD follow its rotating acquisition Cherenkov photon for being imaged.The radiotherapy multi-angle imaging device of radiationless hurtless measure provided by the invention, it is packaged in due to detector in the head of X-ray emission device, it can be during multi-angle roentgenotherapia with head rotating, so its detector gathers signal, from the influence of accelerator rack.This imaging method has the advantages that quick, and 3-D view can move at any time.
Description
Technical field
The invention belongs to radiotherapy equipment technical field, the radiotherapy multi-angle imaging for being related to a kind of radiationless hurtless measure fills
It puts.
Background technology
At present, radiotherapy has become one of standard care means after tumor of breast Breast reservation.In order to reduce radiotherapy
Site error, the development of image guided radiation therapy technology are swift and violent.
2006, VARIAN Oncology Systems and Sweden's medical courses in general developed radiological imaging system up to company, in two machineries
KV-x-ray bulb and one piece of large scale Amorphous silicon flat-panel detectors on arm are installed respectively, while KV images and MV shadows can be gathered
Picture.The real-time breathing tracing system of An Kerui companies of U.S. research and development, by being distributed in indoor 2 cameras and amorphous silicon detector
Composition, is merged in the form of 2D or 3D with digital image rebuilding DRR, so as to the position of the velocity estimated patient of near real-time
Variation is put, and the movement of patient is corrected in time over the course for the treatment of.But above scheme uses the side of X-ray radiation
Formula makes patient receive unnecessary dose irradiation, and can not accomplish to verify the accuracy that tumour receives dosage.
2014, VARIAN Oncology Systems and Sweden's medical courses in general were developed radiological imaging system image taking speed up to company and are being divided
Clock magnitude, and patient respiratory cycle can not accomplish the real time imagery of tumor of breast in millisecond magnitude.
2016, the C-Dose of DoseOptics companies of U.S. production was that the currently the only tumour radiotherapy that is developed to apply to is controlled
Cherenkov's luminescence imaging (Cerenkov luminescence imaging, CLI) equipment for the treatment of, when which has imaging
Between it is short, sensitivity is good, cost-effective, it is radiationless many advantages, such as, applied to tumor of breast treatment dosage imaging research in.
But since the C-Dose release times are shorter, some outstanding problems are also exposed in application process.In breast cancer treatment mistake
Cheng Zhong, detector are placed in fixed position around, and investigative range is limited, particularly in multi-angle therapeutic process, treatment angle it is more and
Variation is fast, and detector is influenced be subject to accelerator rack, can not gather signal；There is also similar in the intensity modulated therapy of multi-angle
The problem of, factors above limits applications of the CLI in complicated tumour radiotherapy technology.
The content of the invention
Present invention solves the problem in that providing a kind of radiotherapy multi-angle imaging device of radiationless hurtless measure, pass through acquisition
The Cherenkov's photon generated during radiotherapy is gathered by multi-angle and is imaged, to body surface organization's absorbed dose of radiation imaging.
The present invention is to be achieved through the following technical solutions：
A kind of radiotherapy multi-angle imaging device of radiationless hurtless measure, including the detection being connected with X-ray emission device
Device, the detector include being packaged in shell for gathering the CCD of Cherenkov's photon, and filter plate is additionally provided on CCD；
The detector is packaged in front of the KV grade X-rays bulb of X-ray emission device, orthogonal with MV grades of heads；
At least 180 ° of the rotatable irradiation of MV grade heads of the X-ray emission device, CCD follows its rotating acquisition to cut human relations
Section's husband's photon is used to be imaged.
The detection angle of the detector and MV grades of x-ray angles are at a right angle, change with MV grades of x-ray angles and change.
The CCD is by the filter plate of 695-770nm, Cherenkov's photon that human body generates when gathering radiotherapy,
To body surface organization's absorbed dose of radiation imaging.
Compared with prior art, the present invention has technique effect beneficial below：
The radiotherapy multi-angle imaging device of radiationless hurtless measure provided by the invention, while roentgenotherapia tumour into
Row imaging；Body surface, with 60 degree of the angle of divergence, emits Cherenkov's photon while X-ray is absorbed；The CCD of detector can be adopted
Collect Cherenkov's photon two-dimensional imaging.Because Cherenkov's photon relation proportional to body surface organization absorbed dose of radiation, Cherenkov
Photon two dimensional image can be exchanged into two-dimentional dosage imaging.
The radiotherapy multi-angle imaging device of radiationless hurtless measure provided by the invention, since detector is packaged in X-ray hair
In the head of injection device, can during multi-angle roentgenotherapia with head rotating, so its detector gather signal,
From the influence of accelerator rack.
The radiotherapy multi-angle imaging device of radiationless hurtless measure provided by the invention is combined hard using CCD and filter plate
Multigroup two dimensional image is redeveloped into 3-D view by part structure using mixed spectrum Cherenkov's luminescence imaging method.This imaging side
Method has the advantages that quick, and 3-D view can move at any time, can further form four-dimensional dynamic surface dose imaging.
The present invention collects Cherenkov's photon imaging that tumour radiotherapy process itself generates, and does not utilize additional ray
Patient is irradiated, interference is not generated to the treatment of patient, accomplishes radiationless, noninvasive dosage imaging.
Description of the drawings
Fig. 1 is the structural diagram of the present invention；
Fig. 2 is the panel detector structure schematic diagram of the present invention；
Fig. 3 is imaging results figure of the present invention.
Wherein, 1 is MV grades of X-ray head CCD of outgoing；2 be KV grades of X-ray bulbs of outgoing；3 be detector；4 be CCD；5
For filter plate.
Specific embodiment
With reference to specific embodiment, the present invention is described in further detail, it is described be explanation of the invention and
It is not to limit.
As shown in Figure 1, a kind of radiotherapy multi-angle imaging device of radiationless hurtless measure, including with X-ray emission device phase
The detector of connection, the detector include being packaged in shell for gathering the CCD of Cherenkov's photon, also be set on CCD
There is filter plate；
The detector is packaged in front of the KV grade X-rays bulb of X-ray emission device, orthogonal with MV grades of heads；
At least 180 ° of the rotatable irradiation of MV grade heads of the X-ray emission device, CCD follows its rotating acquisition to cut human relations
Section's husband's photon is used to be imaged.
Further, the detection angle of the detector and MV grades of x-ray angles are at a right angle, change with MV grades of x-ray angles
Become and change.Specifically, filter plates of the CCD by 695-770nm, the Qie Lunke that human body generates when gathering radiotherapy
Husband's photon, to body surface organization's absorbed dose of radiation imaging.MV grades of heads go out roentgenotherapia, and during x-ray bombardment body surface, generation is cut
Lun Kefu is radiated, and detector acquisition Cherenkov's photon is imaged External absorbability x-ray dose.
As shown in Fig. 2, being sky among detector parts, X-ray bulb transmitting X-ray is not influenced.Detector wall material simultaneously
Expect for alloy material, shielding X-ray, the influences of KV grades and MV grades rays of elimination.
Some design parameters of CCD are given below.
Specific occupation mode is given below：
1st, before tumour radiotherapy starts, the combination of detector is selected, selects imaging pattern.
2nd, detector switch is opened in software, it is standby.
3rd, tumour radiotherapy starts, and can show that body surface exposure dose is imaged in software, and CCD imagings need to imported into calculating
On machine, the software LightField (Princeton University's instrument, Trenton, New Jersey) carried by CCD is shown, imaging knot
Fruit is as shown in Figure 3.
Example given above is to realize the present invention preferably example, and the invention is not restricted to above-described embodiments.This field
Technical staff's technical solution according to the present invention technical characteristic any nonessential addition, the replacement made, belong to this
The protection domain of invention.
Claims (3)
1. a kind of radiotherapy multi-angle imaging device of radiationless hurtless measure, which is characterized in that including being connected with X-ray emission device
The detector connect, the detector include being packaged in shell for gathering the CCD of Cherenkov's photon, be additionally provided on CCD
Filter plate；
The detector is packaged in front of the KV grade X-rays bulb of X-ray emission device, orthogonal with MV grades of heads；
At least 180 ° of the rotatable irradiation of MV grade heads of the X-ray emission device, CCD follows its rotating acquisition Cherenkov
Photon is used to be imaged.
2. the radiotherapy multi-angle imaging device of radiationless hurtless measure as described in claim 1, which is characterized in that the detector
Detection angle and MV grades of x-ray angles it is at a right angle, change with MV grades of x-ray angles and change.
3. the radiotherapy multi-angle imaging device of radiationless hurtless measure as described in claim 1, which is characterized in that the CCD
Pass through the filter plate of 695-770nm, Cherenkov's photon that human body generates when gathering radiotherapy, to body surface organization's absorbed dose of radiation
Imaging.
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| CN201711415122.7A CN108057179B (en) | 2017-12-20 | 2017-12-20 | Multi-angle imaging device for radiation-free and non-invasive radiotherapy |
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| CN201711415122.7A CN108057179B (en) | 2017-12-20 | 2017-12-20 | Multi-angle imaging device for radiation-free and non-invasive radiotherapy |
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| CN108057179A true CN108057179A (en) | 2018-05-22 |
| CN108057179B CN108057179B (en) | 2019-12-24 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110515114A (en) * | 2019-08-26 | 2019-11-29 | 西安交通大学医学院第一附属医院 | Cherenkov's optical acquisition device and acquisition method in a kind of high-performance Patients During Radiotherapy |
| CN116966448A (en) * | 2023-09-22 | 2023-10-31 | 迈胜医疗设备有限公司 | FLASH treatment system, cerenkov detector, beam current measuring device and method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110515114A (en) * | 2019-08-26 | 2019-11-29 | 西安交通大学医学院第一附属医院 | Cherenkov's optical acquisition device and acquisition method in a kind of high-performance Patients During Radiotherapy |
| CN110515114B (en) * | 2019-08-26 | 2022-07-29 | 西安交通大学医学院第一附属医院 | Cerenkov light collection device and collection method in high-performance radiotherapy process |
| CN116966448A (en) * | 2023-09-22 | 2023-10-31 | 迈胜医疗设备有限公司 | FLASH treatment system, cerenkov detector, beam current measuring device and method thereof |
| CN116966448B (en) * | 2023-09-22 | 2023-12-08 | 迈胜医疗设备有限公司 | FLASH treatment system, cerenkov detector, beam current measuring device and method thereof |
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