CN108057071A - A kind of drug for treating gastritis and preparation method thereof - Google Patents

A kind of drug for treating gastritis and preparation method thereof Download PDF

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Publication number
CN108057071A
CN108057071A CN201810162018.XA CN201810162018A CN108057071A CN 108057071 A CN108057071 A CN 108057071A CN 201810162018 A CN201810162018 A CN 201810162018A CN 108057071 A CN108057071 A CN 108057071A
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CN
China
Prior art keywords
drug
powder
filtrate
fructus aurantii
treating gastritis
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Pending
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CN201810162018.XA
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Chinese (zh)
Inventor
苏占玉
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Individual
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Individual
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Priority to CN201810162018.XA priority Critical patent/CN108057071A/en
Publication of CN108057071A publication Critical patent/CN108057071A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535Perilla (beefsteak plant)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a kind of drugs for treating gastritis, more specifically, it be Eclipta prostrata, perilla seed, the root of three-nerved spicebush, Fructus Aurantii, corydalis tuber, dried orange peel be raw material, it prepares, through decocting, filtering, drying, sterilizes in proportion, after the processing such as crushing, powder, capsule or pill is made, formula of the invention is evident in efficacy to the treatment of gastritis, has no drug dependence.

Description

A kind of drug for treating gastritis and preparation method thereof
Technical field
The present invention relates to a kind of drug for treating gastritis, more specifically, it be in being prepared using Chinese herbal medicine as raw material into Medicine, the invention further relates to the preparation methods of the drug.
Background technology
Gastritis refers to the inflammatory variation of the acute or chronic gastric mucosa caused by a variety of causes, it is a kind of common in crowd Sick frequently-occurring disease, incidence is higher, and the course of disease is long and is not easy to fully recover, and seriously endangers the health of the mankind.When the sufferer state of an illness is broken out, usually It is relieved pain with Western medicine, Western medicine analgesic often causes dependence, drug resistance and with certain side effect, although also there is some treatments The Chinese patent drug of gastritis, but since curative effect is not very good, patient still has to depending on western medicine.
The content of the invention
The diseases such as superficial gastritis, chronic gastritis, non-ulcer dyspepsia are treated it is an object of the invention to provide a kind of The drug of disease.
It is a further object of the present invention to provide the preparation methods of the drug.
The solution of the present invention be based on traditional Chinese medicine to gastritis understanding and principle of reatment, with reference to pathological research achievement, Pleasant analgesic, the sharp gas of promoting blood circulation, warming kidney for dispelling cold, smooth liver and relieve pain, righting reinforcing, the natural plants treated both principal and secondary aspect of disease are filtered out from Chinese medicine Medicine by traditional Chinese medical science monarch, minister, helps, makes theoretical prescription, skims the cream off milk, and makes it analgesic, spasmolysis, anti-inflammatory, antiulcer play hepar sulfuris qi-regulating And the effect of stomach and alleviating pain, so as to achieve the purpose that treat gastritis.
The drug of the present invention is made of following component (dosage is parts by weight):
Eclipta prostrata 2-7 perilla seed 1-5 root of three-nerved spicebush 1-3 Fructus Aurantiis 1-3
Corydalis tuber 0.8-2 dried orange peels 0.3-1
Preparing drug optimum weight (part) proportioning of the present invention is:
3 perilla seed of Eclipta prostrata, 2 root of three-nerved spicebush, 1.5 Fructus Aurantii 2
0.8 dried orange peel 0.5 of corydalis tuber
The preparation method of the present invention:
Its active compound is taken by its drug optimum weight (part) proportioning, perilla seed, the root of three-nerved spicebush, corydalis tuber, dried orange peel remove impurity, clean, and place In decocting container, adding water submerged powder one hour, then heating decocts, and after boiling two hours, takes its filtrate and filters filtrate, Filtrate is for use.Clean ground Eclipta prostrata is added in and decocted in container, boiled one hour before second decocts by the drug in container, Filtrate is taken to filter, third time decoct again one hour, refilter, (every time decoct before will add suitable water, using flood powder as It is accurate).It filtrate will merge three times, the liquid of merging carries out being concentrated into relative density 1.35-1.40kg/m3, becomes medicinal extract and strengthens.
Fructus Aurantii is ground into the powder of even thickness, is screened to 80 mesh.Medicinal extract is poured out again and adds in Fructus Aurantii fine powder, stirring is equal It is even, dry at a temperature of being subsequently placed in 80 DEG C -95 DEG C, sterilizing, then pulverize and sieve to 100 mesh, the pulvis after sterilizing is the present invention The powder of drug, the powder of drug of the present invention can be packed into capsule, and every weight of capsule is 0.4 gram, adds suitable bee close and can be made into Close ball.
Each dosage form curative effect of drug of the present invention is identical, according to the optional different dosage form of needs of patient.
Instructions of taking:It 1.5-2.0 grams/times, taken three times per day, boiling water is taken after mixing it with water before meals, and a month as a course for the treatment of.
Drug of the present invention, no drug dependence, tolerance are that can replace Western medicine with Chinese herbal medicine, change traditional doctor trained in Western medicine pair The therapy of gastritis.
Example patient carries out clinical observation subordinate list:
The effect of in the subordinate list standard:1st, healing-pain disappears 1 year or more and does not recur, gastrocopy no abnormality seen.2nd, have Effect-pain symptom disappears substantially, and appetite is normal.3rd, invalid-curative effect unobvious.It is more satisfactory by statistical form Mingzhi's therapeutic effect, Total effective rate is more than 90%, suitable for promoting.
Clinical drug use of the present invention shows to have the advantage that:
What the 1st, the present invention selected is pure Chinese herbal medicine, and reasonable recipe, medicine source is extensive, cheap, nontoxic to human body, without side-effects;
2nd, the drug needed for prescription of the present invention, need only sorting, remove impurity, clean it is conventional process, so keeping the original of drug There are natural components not to be destroyed, meet pharmacology regulation;
3rd, after drug administration of the invention, stomach is contacted directly, convenient for the absorption to medicament effective component, drug effect is played, has and treat The advantages of journey is short, medication is few, quick, curative effect is high;
4th, the dosage forms such as powder, capsule, pill can be chosen, type of dosage form is more, easy to carry, convenient to take;
5th, medicinal application of the invention is extensive, not only to superficial gastritis, chronic gastritis, atrophic gastritis, non-ulcerative digestion It is bad, and to nausea, acid regurgitation, abdominal distension, deficiency of food be indigestion and loss of appetite etc., illnesss have obvious curative effects.
Specific embodiment
Bulk pharmaceutical chemicals (kilogram) are weighed by following proportionings:
1.5 Fructus Aurantii of Eclipta prostrata 3 perilla seed, 2 root of three-nerved spicebush, 2 corydalis tuber 0.8
Dried orange peel 0.5
Preparation method:
Pacify its drug optimum weight (part) proportioning and take its active compound, perilla seed, the root of three-nerved spicebush, corydalis tuber, dried orange peel remove impurity, clean, and place In decocting container, adding water submerged powder one hour, then heating decocts, and after boiling two hours, takes its filtrate and filters filtrate, Filtrate is for use.Clean Eclipta prostrata is added in and decocted in container, boiled one hour before second decocts by the drug in container, Decoction liquor filter, third time decoct again one hour, refilter, (every time decoct before will add suitable water, using flood powder as It is accurate).It filtrate will merge three times, the liquid of merging carries out being concentrated into relative density 1.35-1.40kg/m3, becomes medicinal extract and strengthens.
Fructus Aurantii is ground into the powder of even thickness, is screened to 80 mesh.Medicinal extract is poured out again and adds in Fructus Aurantii fine powder, stirring is equal It is even, then dry at a temperature of 80 DEG C -95 DEG C, sterilizing, then pulverize and sieve to 100 mesh, the pulvis after sterilizing is medicine of the present invention The powder of object.

Claims (4)

1. a kind of drug for treating gastritis, it is characterised in that be the medicament made of the bulk pharmaceutical chemicals of following weight parts:
Eclipta prostrata 2-7, perilla seed 1-5, root of three-nerved spicebush 1-3, Fructus Aurantii 1-3, corydalis tuber 0.8-2, dried orange peel 0.3-1.
2. a kind of drug for treating gastritis according to claim 1, it is characterised in that each raw material medicines in portions by weight is:
Eclipta prostrata 3, perilla seed 2, the root of three-nerved spicebush 1.5, Fructus Aurantii 2, corydalis tuber 0.8, dried orange peel 0.5.
3. a kind of preparation method for the drug for treating gastritis, which is characterized in that by bulk pharmaceutical chemicals its drug optimum weight (part) proportioning Its active compound is taken, perilla seed, the root of three-nerved spicebush, corydalis tuber, dried orange peel remove impurity, clean, and place in decocting container, add water submerged powder one small When, then heating decocts, and after boiling two hours, takes its filtrate and filters filtrate, filtrate is for use, and the drug in container is second Before secondary decoction, clean Eclipta prostrata is added in and is decocted in container, boils one hour, filtrate is taken to filter, it is small that third time decocts one again When, it refilters, filtrate will merge three times, the liquid of merging carries out being concentrated into relative density 1.35-1.40kg/m3, becomes Medicinal extract is strengthened, and Fructus Aurantii is ground into the powder of even thickness, is screened to 80 mesh, then medicinal extract is poured out and adds in Fructus Aurantii fine powder, and stirring is equal It is even, dry at a temperature of being subsequently placed in 80 DEG C -95 DEG C, sterilizing, then pulverize and sieve to 100 mesh, it is the powder of drug of the present invention.
A kind of 4. drug for treating gastritis according to claim 1 and preparation method thereof, it is characterised in that described medicament It is powder, capsule, pill.
CN201810162018.XA 2018-02-26 2018-02-26 A kind of drug for treating gastritis and preparation method thereof Pending CN108057071A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810162018.XA CN108057071A (en) 2018-02-26 2018-02-26 A kind of drug for treating gastritis and preparation method thereof

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Application Number Priority Date Filing Date Title
CN201810162018.XA CN108057071A (en) 2018-02-26 2018-02-26 A kind of drug for treating gastritis and preparation method thereof

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CN108057071A true CN108057071A (en) 2018-05-22

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Application Number Title Priority Date Filing Date
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130133A (en) * 1990-09-28 1992-07-14 The Procter & Gamble Company Plant extracts as mucosal-protective agents
CN1785362A (en) * 2004-12-10 2006-06-14 赵宏 Medicine for treating gastritis and its preparation method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130133A (en) * 1990-09-28 1992-07-14 The Procter & Gamble Company Plant extracts as mucosal-protective agents
CN1785362A (en) * 2004-12-10 2006-06-14 赵宏 Medicine for treating gastritis and its preparation method

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
KARTHIKUMAR SANKAR等: "Screening of antibacterial and antioxidant activities of leaves of Eclipta prostrata(L)", 《SCIENTIFIC RESEARCH AND ESSAY》 *
TAN庆明: ""延胡索治疗慢性胃炎配方有哪些?", 《HTTPS://IASK.SINA.COM.CN/B/4O1LKIWOJT.HTML》 *
中央人民广播电台《祖国各地》组: "《全国名特产品》", 31 December 1982, 山西人民出版社 *
张伟等: "《民间偏方养生治病一本通》", 30 June 2012, 河北科学技术出版社 *
李莉: "《家庭生活万事通》", 31 January 2005, 内蒙古人民出版社 *

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Application publication date: 20180522