CN108026493A - 一种适用于灌流式培养的组合式生物反应器仓 - Google Patents

一种适用于灌流式培养的组合式生物反应器仓 Download PDF

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CN108026493A
CN108026493A CN201580082994.9A CN201580082994A CN108026493A CN 108026493 A CN108026493 A CN 108026493A CN 201580082994 A CN201580082994 A CN 201580082994A CN 108026493 A CN108026493 A CN 108026493A
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storehouse
bioreactor
combined
combined bioreactor
chamber
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CN108026493B (zh
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刘青
孟潇
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Nanjing ruikangjian Biomedical Technology Co.,Ltd.
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Jiangyin Recongene Biomedical Technologies Co ltd
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    • C12M1/16—Apparatus for enzymology or microbiology containing, or adapted to contain, solid media
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    • C12M23/00—Constructional details, e.g. recesses, hinges
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    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level

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  • Health & Medical Sciences (AREA)
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Abstract

提供一种组合式生物反应器仓，包括形成所述反应器仓腔室的上端部、至少一个中间部和下端部，所述上端部、下端部分别设有与培养液管路连接的接口，所述上端部与中间部间、中间部与下端部间通过连接机构可拆卸地、密封地连接；当中间部的数量≥2时，相邻的中间部通过连接机构可拆卸地、密封地连接；所述腔室还包括供细胞贴附生长的细胞载体。

Description

PCT国内申请，说明书已公开。

Claims (10)

  1. PCT国内申请，权利要求书已公开。
CN201580082994.9A 2015-12-18 2015-12-18 一种适用于灌流式培养的组合式生物反应器仓 Active CN108026493B (zh)

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PCT/CN2015/097855 WO2017101096A1 (zh) 2015-12-18 2015-12-18 一种适用于灌流式培养的组合式生物反应器仓

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110894494A (zh) * 2019-11-22 2020-03-20 广西梧州制药（集团）股份有限公司 一种大规模高密度悬浮培养293细胞高产腺病毒的方法
CN115369036A (zh) * 2022-10-21 2022-11-22 天信和(苏州)生物科技有限公司 细胞培养载体组件及生物反应器

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CN1290744A (zh) * 1999-12-09 2001-04-11 中国科学院力学研究所 逆流透析式空间细胞培养器及培养方法
WO2003085080A1 (en) * 2002-04-04 2003-10-16 Corebiotech Co., Ltd. Cell culture plate and system using the same
JP2004147555A (ja) * 2002-10-30 2004-05-27 Foundation For The Promotion Of Industrial Science 細胞培養装置、バイオリアクター及び細胞培養チャンバー
CN2813625Y (zh) * 2005-05-12 2006-09-06 西北农林科技大学 一种微生物固态补料连续培养用培养器皿
US20100075293A1 (en) * 2008-09-19 2010-03-25 University Of Louisville Research Foundation, Inc. Bioreactors, systems, and methods for vascularizing tissue constructs
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CN102127638A (zh) * 2010-01-12 2011-07-20 李红玉 一种稳定输出Fe3+的生物反应装置和方法
CN104039947A (zh) * 2011-11-07 2014-09-10 荷兰生命科学产品有限公司 用于培养细胞的装置

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US5057221A (en) * 1988-12-19 1991-10-15 Weyerhaeuser Company Aerobic biological dehalogenation reactor
US6197573B1 (en) * 1998-11-17 2001-03-06 Biocon India Limited Solid state fermentation
WO2010032260A1 (en) * 2008-08-05 2010-03-25 Sameer Sudhir Kulkarni Stacked basket bioreactor for solid state fermentation
EP2585579A2 (en) * 2010-06-23 2013-05-01 Stobbe Tech A/s Device and method for industrial cultivation of cells
WO2013074551A1 (en) * 2011-11-14 2013-05-23 Biocee, Inc. Multiphase porous flow reactors and methods of using same
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5240854A (en) * 1989-06-05 1993-08-31 Berry Eric S Continuous high-density cell culture system
CN1290744A (zh) * 1999-12-09 2001-04-11 中国科学院力学研究所 逆流透析式空间细胞培养器及培养方法
WO2003085080A1 (en) * 2002-04-04 2003-10-16 Corebiotech Co., Ltd. Cell culture plate and system using the same
JP2004147555A (ja) * 2002-10-30 2004-05-27 Foundation For The Promotion Of Industrial Science 細胞培養装置、バイオリアクター及び細胞培養チャンバー
CN2813625Y (zh) * 2005-05-12 2006-09-06 西北农林科技大学 一种微生物固态补料连续培养用培养器皿
CN102057033A (zh) * 2008-05-09 2011-05-11 辛尼克萨生命科学（私人）有限公司 可缩放的细胞培养生物反应器和细胞培养方法
US20100075293A1 (en) * 2008-09-19 2010-03-25 University Of Louisville Research Foundation, Inc. Bioreactors, systems, and methods for vascularizing tissue constructs
CN102127638A (zh) * 2010-01-12 2011-07-20 李红玉 一种稳定输出Fe3+的生物反应装置和方法
CN104039947A (zh) * 2011-11-07 2014-09-10 荷兰生命科学产品有限公司 用于培养细胞的装置

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110894494A (zh) * 2019-11-22 2020-03-20 广西梧州制药（集团）股份有限公司 一种大规模高密度悬浮培养293细胞高产腺病毒的方法
CN115369036A (zh) * 2022-10-21 2022-11-22 天信和(苏州)生物科技有限公司 细胞培养载体组件及生物反应器

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WO2017101096A1 (zh) 2017-06-22
US11198840B2 (en) 2021-12-14
US20190031989A1 (en) 2019-01-31

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