CN108024955A - 用于rsv和诺如病毒抗原的小肠递送的制剂 - Google Patents

用于rsv和诺如病毒抗原的小肠递送的制剂 Download PDF

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Publication number
CN108024955A
CN108024955A CN201680046440.8A CN201680046440A CN108024955A CN 108024955 A CN108024955 A CN 108024955A CN 201680046440 A CN201680046440 A CN 201680046440A CN 108024955 A CN108024955 A CN 108024955A
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Prior art keywords
vaccine
rsv
group
immunogenic composition
subjects
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Pending
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CN201680046440.8A
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English (en)
Chinese (zh)
Inventor
乔治·特拉格
肖恩·塔克
金利宣
夏兰·斯卡伦
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Vaxart Inc
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Vaxart Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57503876&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN108024955(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vaxart Inc filed Critical Vaxart Inc
Priority to CN202311287963.XA priority Critical patent/CN118045170A/zh
Publication of CN108024955A publication Critical patent/CN108024955A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A61K48/0058Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/2004Excipients; Inactive ingredients
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    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
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    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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    • AHUMAN NECESSITIES
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    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
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    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
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    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10041Use of virus, viral particle or viral elements as a vector
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    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
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    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
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    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
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    • C12N2770/16011Caliciviridae
    • C12N2770/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Biochemistry (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201680046440.8A 2015-06-12 2016-06-08 用于rsv和诺如病毒抗原的小肠递送的制剂 Pending CN108024955A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311287963.XA CN118045170A (zh) 2015-06-12 2016-06-08 用于rsv和诺如病毒抗原的小肠递送的制剂

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US201562175081P 2015-06-12 2015-06-12
US62/175,081 2015-06-12
PCT/US2016/036461 WO2016200951A1 (en) 2015-06-12 2016-06-08 Formulations for small intestinal delivery of rsv and norovirus antigens

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CN202311287963.XA Division CN118045170A (zh) 2015-06-12 2016-06-08 用于rsv和诺如病毒抗原的小肠递送的制剂

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CN202311287963.XA Pending CN118045170A (zh) 2015-06-12 2016-06-08 用于rsv和诺如病毒抗原的小肠递送的制剂

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US (3) US11433146B2 (https=)
EP (2) EP3307239B1 (https=)
JP (2) JP6912394B2 (https=)
KR (2) KR102678401B1 (https=)
CN (2) CN108024955A (https=)
AU (1) AU2016274599B2 (https=)
CA (1) CA2988761A1 (https=)
DK (1) DK3307239T3 (https=)
EA (1) EA201792512A1 (https=)
ES (1) ES2832504T3 (https=)
WO (1) WO2016200951A1 (https=)
ZA (1) ZA201708434B (https=)

Cited By (1)

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CN108904795A (zh) * 2018-08-29 2018-11-30 温氏食品集团股份有限公司 一种猪流行性腹泻病毒的口服疫苗的制备方法

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CA3048313A1 (en) * 2017-01-06 2018-07-12 Stabilitech Biopharma Ltd Virus
WO2019104439A1 (en) 2017-11-30 2019-06-06 Medicago Inc. Modified norovirus vp1 proteins and vlps comprising modified norovirus vp1 proteins
US20210311600A1 (en) * 2020-04-06 2021-10-07 Kirk David Bacon Seat Selection Application For Social Distancing Compliance
WO2024193965A1 (en) * 2023-03-17 2024-09-26 Glaxosmithkline Biologicals Sa Rsv-f-encoding nucleic acids

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