CN107997968B - Soft capsule manufacturing process - Google Patents
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- CN107997968B CN107997968B CN201711218210.8A CN201711218210A CN107997968B CN 107997968 B CN107997968 B CN 107997968B CN 201711218210 A CN201711218210 A CN 201711218210A CN 107997968 B CN107997968 B CN 107997968B
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- gelatin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/078—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of wafers or cachets
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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Abstract
The invention discloses a process for preparing soft capsules, which comprises the following steps that gelatin descends to the lower port of a gelatin forming tube, liquid medicine is dripped into gelatin liquid at the lower port of the gelatin forming tube, gelatin liquid drops wrapped with the liquid medicine pass through a through hole of a turntable and are gradually cooled and hardened, a hollow motor rotates, soft capsules dripped and hung at the lower port of the gelatin forming tube drop by the inertia effect and generate torsion with the lower port of the gelatin forming tube, and a formed soft capsule film is hardened and falls into a material box.
Description
Technical Field
The invention relates to the field of soft capsule forming, in particular to a soft capsule manufacturing process.
Background
Since the introduction of foreign equipment for soft capsule molding in China in the eighties of the last century to produce soft capsule products, the existing equipment for soft capsule molding in domestic surveying and mapping production is always the mainstream soft capsule production equipment in the Chinese market, and due to the technology lag, the equipment can not meet the requirements of the production of soft capsule products such as modern Chinese medicines, health-care foods, cosmetics, paintballs and the like.
Therefore, the Chinese invention with the prior publication number of CN103211706A discloses a device for forming soft capsules, which comprises a machine body, a left gelatin roller, a left gelatin box, a left rubber drawing roller, a machine head, a left die, a right die, a spraying body, a feeding pump, a feeding hopper, a right gelatin roller, a right gelatin box, a right rubber drawing roller, a touch screen and a PLC electrical control system; the touch screen is connected with the PLC electrical control system through a circuit, a left die shaft, a right die shaft and a guide plate are arranged in the machine head, and a pump main shaft, a reversing plate and a pump plunger piston are arranged in the feeding pump; the machine head is also provided with a left mould shaft servo speed reducing motor for driving the left mould shaft to rotate in a rotating direction and a right mould shaft servo speed reducing motor for driving the right mould shaft to rotate in a rotating direction opposite to the direction of the left mould shaft; the feeding pump is provided with a pump main shaft servo speed reduction motor and a pump main shaft gear rack group, the pump main shaft servo speed reduction motor is connected with the pump main shaft gear rack group through a pump main shaft, and drives a guide plate and a pump plunger to reciprocate through the pump main shaft gear rack group.
For another example, chinese invention with publication number CN104116639B discloses "an apparatus for soft capsule molding", which includes a gelatin coating mechanism for generating a gelatin skin, a transmission mechanism for transmitting the gelatin skin, a liquid medicine injection mechanism, a mold rolling and pressing mechanism and a conveyor belt, wherein the gelatin coating mechanism includes a rubber barrel, a coating box, a left rubber wheel and a right rubber wheel, the transmission mechanism includes a left oil rolling system and a right oil rolling system, the liquid medicine injection mechanism includes a liquid medicine box, a liquid medicine conduit connected with the liquid medicine box and a hollow liquid medicine spray pipe, and the mold rolling and pressing mechanism includes a left mold rolling and a right mold rolling; the transmission mechanism is also provided with a left transmission roller, a right transmission roller and a control system, the left transmission roller is arranged above the left rolling die, the right transmission roller is arranged above the right rolling die, and the control system controls the left transmission roller and the right transmission roller to transmit the rubber to the area between the left rolling die and the right rolling die; the liquid medicine injection mechanism is also provided with an action system, the action system is fixedly connected with a liquid medicine spray pipe, one end of the liquid medicine spray pipe is provided with a liquid medicine nozzle, the other end of the liquid medicine spray pipe is connected with a liquid medicine conduit, the liquid medicine conduit is an elastic hose, the liquid medicine spray pipe is vertically downward, the liquid medicine nozzle is right opposite to the area between the left rolling die and the right rolling die, the aperture of the liquid medicine nozzle is equal to the aperture of the inner wall of the liquid medicine spray pipe, the radius of the outer wall of the liquid medicine spray pipe is smaller than the thickness of the rubber, the axis of the liquid medicine nozzle is superposed with the axis of the liquid medicine spray pipe, the action system comprises a motor, a slide way, a ball screw, a slide block and a connecting rod, one end of the ball screw is connected with the motor, the other end of the ball screw is connected with one side of the slide block, the other side, the liquid medicine spray pipe is arranged in the mounting hole, the liquid medicine spray pipe extends out of the connecting rod, the sliding block slides back and forth on the sliding way, the sliding way is arranged above the rolling die pressing mechanism, and the direction of the sliding way is parallel to the axis of the liquid medicine spray pipe and is vertical to the axes of the left rolling die and the right rolling die.
Disclosure of Invention
The invention aims to solve the technical problem of the prior art, and provides a soft capsule manufacturing process which realizes automatic forming of soft capsules and has high forming efficiency.
The technical scheme adopted by the invention for solving the technical problems is as follows: the manufacturing process of the soft capsule is characterized by comprising the following steps:
(1) the gelatin conveying pump conveys the gelatin liquid in the gelatin barrel into the gelatin distributor, the gelatin distributor conveys the gelatin into each corresponding gelatin conveying pipe and finally enters each gelatin forming pipe, and the gelatin liquid in the gelatin forming pipes descends to the lower port of the gelatin forming pipe along the wall under the action of gravity;
(2) the gelatin solution begins to overflow out of the lower port of the gelatin forming tube, at the moment, the medicine liquid in the medicine barrel is conveyed to the medicine liquid distributor by the medicine liquid conveying pump, the medicine liquid distributor conveys the medicine liquid into each corresponding medicine liquid conveying tube and finally enters each medicine liquid forming tube, the medicine liquid descends along the tube wall of the medicine liquid forming tube, one drop of the medicine liquid drops into the gelatin solution at the lower port of the gelatin forming tube and is wrapped by the gelatin solution, and the gelatin solution exposed outside the lower port of the gelatin forming tube begins to cool and harden;
(3) the liquid medicine conveying pump stops conveying, the second vacuum pump works, suction is formed at the upper part in the liquid medicine forming pipe, and liquid medicine in the liquid medicine forming pipe stops descending by overcoming gravity and is suspended in the liquid medicine forming pipe;
(4) gelatin solution at the lower end of the gelatin forming tube is continuously gathered at the lower end port of the gelatin forming tube, and the gelatin solution gradually wraps the liquid medicine dripped into the gelatin solution;
(5) stopping the gelatin conveying pump, and operating the first vacuum pump to form an upward suction force on the upper part of the gelatin conveying pipe so as to slow down the dripping of gelatin liquid at the lower port of the gelatin conveying pipe;
(6) the gelatin liquid drops wrapped with the liquid medicine pass through the through hole of the turntable and are gradually cooled to harden, the hollow motor drives the gelatin forming tube to rapidly rotate for a plurality of circles, the soft capsules dripped on the lower port of the gelatin forming tube are subjected to the inertia effect and generate the torsional force with the lower port of the gelatin forming tube to fall off, and the formed soft capsule film hardens and falls into the bin;
(7) and (5) resetting the hollow motor by rotating reversely, and entering the step (1) again.
Further, a cold air generator is arranged at the rotating disc, and in the step (6), cold air is blown into the gelatin liquid drops by the cold air generator.
Furthermore, a conical dropping head part is formed at the lower end of the liquid medicine forming tube, and the liquid medicine is convenient to drop into the gelatin solution by the aid of the dropping head part.
Compared with the prior art, the invention has the advantages of solving the second technical problem: the invention utilizes the drip irrigation mode of the gelatin forming tube to form the gelatin skin outside the soft capsule, utilizes the liquid medicine forming tube to add the liquid medicine inside the soft capsule, and hides the lower port of the liquid medicine forming tube in the lower port of the gelatin forming tube, thereby ensuring that when the gelatin liquid is extruded out of the lower port of the gelatin forming tube, the thickness of the bottom of the gelatin liquid is thicker, avoiding the gelatin skin from cracking in the subsequent dropping process of the gelatin liquid, simultaneously, when the gelatin liquid begins to be extruded out of the lower port of the gelatin forming tube, the liquid medicine is dropped into the gelatin liquid by the liquid medicine delivery pump, then the liquid medicine is prevented from continuously dropping by the second vacuum pump, then the gelatin liquid continues to descend, the gelatin liquid is formed at the lower port of the gelatin forming tube like dropping liquid, in the process, the gelatin liquid in the gelatin forming tube wraps the liquid medicine dropped from the liquid medicine forming tube, so that the gelatin completely wraps the, utilize first vacuum pump to prevent that gelatin liquid measure transition from descending, at last, utilize hollow motor to drive the gelatin forming tube and rotate several circles fast, the softgel that drips and hangs in port department under the gelatin forming tube receives inertial action and produces the torsional force with port under the gelatin forming tube, and fashioned softgel film sclerosis falls into the workbin.
Drawings
FIG. 1 is an exploded view schematically showing an apparatus for forming soft capsules according to an embodiment of the present invention;
FIG. 2 is a schematic view showing an installation structure of the soft capsule molding unit and the fixing plate of FIG. 1;
FIG. 3 is a schematic view showing the structure of a gelatin forming tube and a liquid medicine forming tube in the embodiment of the present invention;
FIG. 4 is a cross-sectional view of a soft capsule in an embodiment of the invention.
Detailed Description
The invention is described in further detail below with reference to the accompanying examples.
As shown in fig. 1 to 4, the apparatus for soft capsule molding in the present embodiment includes a glue solution injection unit 1, a liquid medicine injection unit 2, a fixing plate 3, and a plurality of soft capsule molding units 4 arranged in a ring shape on the fixing plate 3.
The gelatin solution injection assembly 1 comprises a gelatin barrel 11 for containing gelatin solution, a gelatin delivery pump 12 connected with the gelatin barrel 11 and used for delivering the gelatin solution, and a first vacuum pump 13 for pumping the gelatin solution upwards, wherein the gelatin delivery pump 12 is provided with a gelatin delivery port 121, and the first vacuum pump 13 is provided with a first pumping port 131;
the liquid medicine injection assembly 2 comprises a liquid medicine barrel 21 for containing liquid medicine, a liquid medicine delivery pump 22 connected with the liquid medicine barrel 21 for delivering the liquid medicine, and a second vacuum pump 23 for pumping the liquid medicine upwards, wherein the liquid medicine delivery pump 22 is provided with a liquid medicine delivery port 221, and the second vacuum pump 23 is provided with a second pumping port 231;
a plurality of mounting holes 31 are formed in the fixing plate 3, a hollow motor 5 is arranged at each mounting hole 31, a machine body 51 of the hollow motor 5 is arranged on the fixing plate 3, an output shaft of the hollow motor 5 penetrates through the mounting holes 31, the output shaft of the hollow motor 5 penetrates through the machine body 51 of the hollow motor 5, and a through hole 52 is formed in the middle of the output shaft of the hollow motor 5;
each soft capsule forming unit 4 comprises a gelatin forming tube 41 arranged in a through hole 52 corresponding to the output shaft of the hollow motor on the fixing plate 3, and a liquid medicine forming tube 42 arranged in the gelatin forming tube 41, wherein the lower end opening of the gelatin forming tube 41 is gradually reduced in diameter, a shrinking part 411 is formed at the lower end opening of the gelatin forming tube 4, furthermore, an elastic gasket is arranged between the inner wall of the through hole 52 of the output shaft of the hollow motor 5 and the outer wall of the gelatin forming tube 4, an opening at the lower end of the liquid medicine forming tube 42 is arranged in the gelatin forming tube 41 and close to the lower end opening of the gelatin forming tube 41, a gelatin sealing plug 43 is arranged in the gelatin forming tube 41, a gelatin conveying tube 431 and a first exhaust tube 432 are arranged on the gelatin 43, a liquid medicine sealing plug 44 is arranged in the liquid medicine forming tube 42, and a liquid medicine conveying;
a gelatin distributor 7, a liquid medicine distributor, a first vacuum distributor and a second vacuum distributor are vertically arranged above the fixing plate 3, the gelatin distributor 7 comprises a gelatin main pipe 71 connected with a gelatin delivery port 121, a plurality of concentrically arranged gelatin circular pipes 72, and a plurality of gelatin connecting pipes 73 radially arranged to communicate each gelatin circular pipe 72 with the gelatin main pipe 71, and each gelatin delivery pipe 431 is communicated with the gelatin circular pipe 72 of the corresponding section; the liquid medicine distributor comprises a liquid medicine main pipe connected with the liquid medicine delivery port 221, a plurality of liquid medicine circular pipes concentrically arranged, and a plurality of liquid medicine connecting pipes radially arranged to connect each liquid medicine circular pipe and the liquid medicine main pipe, wherein each liquid medicine delivery pipe 441 is communicated with the liquid medicine circular pipe of the corresponding section; the first vacuum distributor comprises a first vacuum main pipe connected with the first pumping hole 131, a plurality of first vacuum circular pipes concentrically arranged, and a plurality of first vacuum connecting pipes radially arranged to connect each first vacuum circular pipe and the first vacuum main pipe, wherein the first pumping pipe 432 is communicated with the first vacuum circular pipe of the corresponding section; the second vacuum distributor includes a second main vacuum pipe connected to the second pumping hole 231, a plurality of second vacuum loops concentrically arranged, and a plurality of second vacuum connection pipes radially arranged to connect each of the second vacuum loops and the second main vacuum pipe, and the second pumping hole 442 is connected to the second vacuum loop of the corresponding segment.
Further, a viscosity detector is arranged in the glue barrel 11, a heater for heating the gelatin solution in the glue barrel 11 is arranged outside the glue barrel 11, the viscosity of the gelatin solution is monitored in real time by arranging the age detector, and the viscosity of gelatin is controlled by the heater, so that the gelatin solution is ensured to be within a required viscosity range at any time.
In addition, a cold air generator is arranged below the rotary disc 5, and cold air is generated by the cold air generator to accelerate the cooling and solidification of gelatin solution, so that the gelatin skin 61 wrapping the outside of the medicine solution can be hardened after the soft capsule 6 is formed.
In addition, the invention also provides a soft capsule manufacturing process, which comprises the following steps:
(1) the gelatin conveying pump 12 conveys the gelatin liquid in the gelatin barrel 11 into the gelatin distributor 7, the gelatin distributor 7 conveys the gelatin into each corresponding gelatin conveying pipe 431 and finally into each gelatin forming pipe 41, and the gelatin liquid in the gelatin forming pipe 41 descends to the lower port of the gelatin forming pipe 41 along the wall under the action of gravity;
(2) the gelatin solution begins to overflow from the lower port of the gelatin forming tube 41, at this time, the medicine liquid delivery pump 22 delivers the medicine liquid in the medicine barrel 21 to the medicine liquid distributor, the medicine liquid distributor delivers the medicine liquid to each corresponding medicine liquid delivery tube 441, and finally enters each medicine liquid forming tube 42, the medicine liquid descends along the tube wall of the medicine liquid forming tube 42, a drop of medicine liquid drops into the gelatin solution at the lower port of the gelatin forming tube 41, and is wrapped by the gelatin solution, and the gelatin solution exposed outside the lower port of the gelatin forming tube 41 begins to cool and harden;
(3) the liquid medicine conveying pump 22 stops conveying, the second vacuum pump 23 works, suction is formed at the upper part in the liquid medicine forming pipe 42, and liquid medicine in the liquid medicine forming pipe 42 stops descending by overcoming gravity and is suspended in the liquid medicine forming pipe 42;
(4) gelatin solution at the lower end of the gelatin forming tube 41 is continuously gathered at the lower end opening of the gelatin forming tube 41, and the gelatin solution gradually wraps the liquid medicine dripped into the gelatin solution;
(5) the gelatin conveying pump 12 stops working, the first vacuum pump 13 works, upward suction is formed at the upper part of the gelatin conveying pipe 431, and the dropping of gelatin liquid at the lower port of the gelatin conveying pipe 431 is slowed down;
(6) the gelatin liquid drops wrapped with the liquid medicine pass through the through hole 51 of the rotary disc 5 and are gradually cooled to become hard, the hollow motor 5 drives the gelatin forming tube 4 to rapidly rotate for a plurality of circles, the soft capsules dropped on the lower port of the gelatin forming tube 41 generate torsion with the lower port of the gelatin forming tube 4 under the action of inertia, and the formed soft capsule film becomes hard and falls into the material box;
(7) and (5) resetting the hollow motor 5 by rotating reversely, and entering the step (1) again.
Further, a cold air generator is arranged at the rotating disc 5, and in the step (6), cold air is blown into the gelatin liquid drops by the cold air generator.
Furthermore, a conical dropping head part is formed at the lower end of the liquid medicine forming tube 42, and the liquid medicine is conveniently dropped into the gelatin solution by the dropping head part.
The invention utilizes the drip irrigation mode of the gelatin forming tube 41 to form the gelatin skin 61 outside the soft capsule 6, utilizes the liquid medicine forming tube 42 to add the liquid medicine 62 inside the soft capsule 6, the lower port of the liquid medicine forming tube 42 is hidden in the lower port of the gelatin forming tube 41, the thickness of the bottom of the gelatin liquid is ensured to be thicker when the gelatin liquid is extruded out of the lower port of the gelatin forming tube 41, the gelatin skin 61 is prevented from cracking in the subsequent gelatin liquid dripping process, simultaneously, when the gelatin liquid begins to be extruded out of the lower port of the gelatin forming tube 41, the liquid medicine 62 is dripped into the gelatin liquid by the liquid medicine delivery pump 22, then the liquid medicine 62 is prevented from continuously dripping by the second vacuum pump 23, then the gelatin liquid continues to descend, the gelatin liquid is formed at the lower port of the gelatin forming tube 41 like dripping liquid, in the process, the gelatin liquid in the gelatin forming tube 41 wraps the liquid medicine 62 dripped from the, so that the gelatin solution completely wraps the internal liquid medicine 62, then the first vacuum pump 13 is utilized to prevent the gelatin solution from transiting downwards, finally, the hollow motor is utilized to drive the gelatin forming tube to rotate rapidly for a plurality of circles, the soft capsule dripped on the lower port of the gelatin forming tube is subjected to the inertia effect and generates the torsion force with the lower port of the gelatin forming tube, and the formed soft capsule film is hardened and falls into the bin.
Claims (3)
1. The manufacturing process of the soft capsule is characterized by comprising the following steps:
(1) the gelatin conveying pump (12) conveys the gelatin liquid in the gelatin barrel (11) into the gelatin distributor, the gelatin distributor (7) conveys the gelatin into each corresponding gelatin conveying pipe (431) and finally into each gelatin forming pipe (41), and the gelatin liquid in the gelatin forming pipe (41) descends to the lower port of the gelatin forming pipe (41) along the wall under the action of gravity;
(2) the gelatin solution begins to overflow out of the lower port of the gelatin forming tube (41), at the moment, the medicine liquid in the medicine barrel (21) is conveyed to the medicine liquid distributor by the medicine liquid conveying pump (22), the medicine liquid distributor conveys the medicine liquid into each corresponding medicine liquid conveying tube (441) and finally enters each medicine liquid forming tube (42), the medicine liquid descends along the tube wall of the medicine liquid forming tube (42), one drop of medicine liquid is dripped into the gelatin solution at the lower port of the gelatin forming tube (41) and is wrapped by the gelatin solution, and the gelatin solution exposed out of the lower port of the gelatin forming tube (41) begins to cool and harden;
(3) the liquid medicine conveying pump (22) stops conveying, the second vacuum pump (23) works, suction is formed at the upper part in the liquid medicine forming pipe (42), and liquid medicine in the liquid medicine forming pipe (42) stops descending against gravity and is suspended in the liquid medicine forming pipe (42);
(4) gelatin solution at the lower end of the gelatin forming tube (41) is continuously gathered at the lower end port of the gelatin forming tube (41), and the gelatin solution gradually wraps the liquid medicine dripped into the gelatin solution;
(5) the gelatin delivery pump (12) stops working, the first vacuum pump (13) works, an upward suction force is formed at the upper part of the gelatin delivery pipe (431), and the dropping of gelatin liquid at the lower port of the gelatin delivery pipe (41) is slowed down;
(6) the gelatin liquid drops wrapped with the liquid medicine pass through the through hole (52) of the hollow motor (5) and are gradually cooled to harden, the hollow motor (5) drives the gelatin forming tube (41) to rapidly rotate for a plurality of circles, the soft capsule (6) dropped on the lower port of the gelatin forming tube (41) generates torsion force with the lower port of the gelatin forming tube (41) under the action of inertia to fall off, and the formed soft capsule film hardens and falls into the material box;
(7) the hollow motor (5) rotates reversely to reset, and the step (1) is carried out again;
the device comprises a fixing plate (3), a gelatin distributor (7), a liquid medicine distributor, a first vacuum distributor and a second vacuum distributor, wherein the gelatin distributor (7) is vertically arranged above the fixing plate (3), the gelatin distributor comprises a gelatin main pipe (71) connected with a gelatin conveying opening (121), a plurality of gelatin circular pipes (72) which are concentrically arranged, and a plurality of gelatin connecting pipes (73) which are communicated with the gelatin circular pipes (72) and the gelatin main pipe (71) and radially arranged, and each gelatin conveying pipe (431) is communicated with the gelatin circular pipe (72) of the corresponding section; the liquid medicine distributor comprises a liquid medicine main pipe connected with the liquid medicine conveying opening (221), a plurality of liquid medicine circular pipes which are concentrically arranged, and a plurality of liquid medicine connecting pipes which are communicated with the liquid medicine circular pipes and are radially arranged on the liquid medicine main pipe, wherein each liquid medicine conveying pipe (441) is communicated with the liquid medicine circular pipe of the corresponding section; the first vacuum distributor comprises a first vacuum main pipe connected with the first pumping hole (131), a plurality of first vacuum circular pipes which are concentrically arranged, and a plurality of first vacuum connecting pipes which are radially arranged and communicated with the first vacuum circular pipes and the first vacuum main pipe, wherein the first pumping pipe (432) is communicated with the first vacuum circular pipes of the corresponding sections; the second vacuum distributor comprises a second vacuum main pipe connected with the second pumping hole (231), a plurality of second vacuum ring pipes which are concentrically arranged, and a plurality of second vacuum connecting pipes which are radially arranged and are communicated with the second vacuum ring pipes and the second vacuum main pipe, wherein the second pumping hole (442) is communicated with the second vacuum ring pipes of the corresponding sections.
2. The process for manufacturing soft capsules according to claim 1, characterized in that: and (3) arranging a cold air generator at the hollow motor (5), and blowing cold air into the gelatin liquid drops by the cold air generator in the step (6).
3. The process for manufacturing soft capsules according to claim 1, characterized in that: the lower end of the liquid medicine forming pipe (42) is provided with a conical dropping head part.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201711218210.8A CN107997968B (en) | 2017-11-28 | 2017-11-28 | Soft capsule manufacturing process |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201711218210.8A CN107997968B (en) | 2017-11-28 | 2017-11-28 | Soft capsule manufacturing process |
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CN107997968A CN107997968A (en) | 2018-05-08 |
CN107997968B true CN107997968B (en) | 2021-03-09 |
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CN201711218210.8A Expired - Fee Related CN107997968B (en) | 2017-11-28 | 2017-11-28 | Soft capsule manufacturing process |
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Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
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BE544714A (en) * | 1955-01-28 | |||
GB1572226A (en) * | 1977-11-03 | 1980-07-30 | Hoechst Uk Ltd | Pharmaceutical preparations in solid unit dosage form |
US7025911B2 (en) * | 2002-09-13 | 2006-04-11 | Freund Corporation | Manufacturing method for oral quick-dissolving seamless capsule |
CN2794513Y (en) * | 2005-05-11 | 2006-07-12 | 闵金杆 | Dripping pill machine |
CN201750916U (en) * | 2010-06-07 | 2011-02-23 | 湖北中烟工业有限责任公司 | Three-layer soft capsule dropper head device |
CN201750917U (en) * | 2010-06-07 | 2011-02-23 | 湖北中烟工业有限责任公司 | Experimental glass device for soft-capsule pills |
CN105878029A (en) * | 2014-12-10 | 2016-08-24 | 烟台百药泰中药科技有限公司 | Seamless gelatin pearl preparing method |
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2017
- 2017-11-28 CN CN201711218210.8A patent/CN107997968B/en not_active Expired - Fee Related
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