CN107997961B - Dispensing device, adapter and dispensing method - Google Patents

Dispensing device, adapter and dispensing method Download PDF

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Publication number
CN107997961B
CN107997961B CN201810059487.9A CN201810059487A CN107997961B CN 107997961 B CN107997961 B CN 107997961B CN 201810059487 A CN201810059487 A CN 201810059487A CN 107997961 B CN107997961 B CN 107997961B
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adapter
medicine bottle
infusion bag
medicine
vial
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CN201810059487.9A
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CN107997961A (en
Inventor
鲍明静
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048Connecting means
    • A61J1/2051Connecting means having tap means, e.g. tap means activated by sliding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048Connecting means
    • A61J1/2055Connecting means having gripping means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048Connecting means
    • A61J1/2058Connecting means having multiple connecting ports

Abstract

The invention discloses a dispensing device, which is suitable for mixing medicine powder in a medicine bottle with liquid medicine in an infusion bag to complete dispensing, and comprises: a base; the rotating assembly is arranged on the base; the base plate is connected with the rotating assembly and is suitable for rotating under the driving of the rotating assembly; the clamping component is arranged on the substrate and is suitable for fixing the medicine bottle, the infusion bag and the adapter, and the adapter is respectively connected with the medicine bottle and the infusion bag; the pressure adjusting component arranged on the base is connected with the adapter and is suitable for adjusting the air pressure in the medicine bottle. The invention also discloses a corresponding adapter and a dispensing method. According to the technical scheme, the relative positions of the medicine bottle and the infusion bag in the vertical direction are adjusted through the rotating assembly, and the air pressure in the medicine bottle is adjusted through the pressure adjusting assembly, so that the medicine powder in the medicine bottle and the medicine liquid in the infusion bag can be mixed, the automation and the convenience of the medicine dispensing process are realized, the labor intensity of medical personnel is reduced, the medicine dispensing efficiency is high, and the medicine dispensing process is safe and reliable.

Description

Dispensing device, adapter and dispensing method
Technical Field
The invention relates to the technical field of medical equipment, in particular to a dispensing device, an adapter and a dispensing method.
Background
The medicine bottle is a container for containing medicine powder or medicine liquid, the bottle cap of the medicine bottle is usually made of rubber, and a layer of aluminum foil is sleeved outside the rubber for sealing.
The medicine bottle can be used for containing medicine powder for transfusion. When dispensing medicine to the powder in the medicine bottle, generally need medical personnel to adopt the syringe earlier to aspirate the liquid medicine from the infusion bag, insert the medicine bottle with the syringe needle of syringe again, inject the liquid medicine into the medicine bottle, handheld medicine bottle rocks, makes the powder in the medicine bottle fully dissolve in the liquid medicine, then inserts the medicine bottle with the syringe needle of syringe, pumps out the liquid medicine in the medicine bottle, and at last, pours into the infusion bag with the liquid medicine in the cylinder of syringe, accomplishes the transfer of powder in the medicine bottle and dispenses. The dispensing method needs manual operation, is complex in operation, consumes long time and has high labor intensity of medical staff. In addition, the use of a syringe for aspirating and injecting a liquid medicine is dangerous, easily causes injury to medical staff, and may cause contamination of the medicine due to contact with the medical staff.
Disclosure of Invention
To this end, the present invention provides a dispensing device, an adapter and a dispensing method that solve or at least alleviate the above-identified problems.
According to an aspect of the present invention, there is provided a dispensing device adapted to mix a drug powder in a drug vial with a drug solution in an infusion bag to complete dispensing, the device comprising: a base; the rotating assembly is arranged on the base; the base plate is connected with the rotating assembly and is suitable for rotating under the driving of the rotating assembly; the clamping component is arranged on the substrate and is suitable for fixing the medicine bottle, the infusion bag and the adapter, and the adapter is suitable for being connected with the medicine bottle and the infusion bag respectively; the pressure adjusting assembly is arranged on the base, connected with the adapter and suitable for adjusting air pressure in the medicine bottle.
Optionally, in the dispensing device according to the present invention, the pressure adjusting assembly includes a cavity, a piston member disposed in the cavity, and a moving mechanism connected to the piston member, one end of the cavity is connected to the adaptor, and the piston member is adapted to reciprocate linearly in the cavity under the driving of the moving mechanism, so as to adjust the air pressure in the medicine bottle.
Optionally, in the dispensing device according to the invention, one end of the cavity is connected to the adapter by a conduit.
Optionally, in the dispensing device according to the invention, the conduit is a flexible hose of gum.
Optionally, in the dispensing device according to the present invention, a translation assembly is further included, which is disposed on the base plate, and is connected to the clamping assembly, and adapted to adjust a position of the clamping assembly in a horizontal direction and/or a vertical direction, so as to adjust a position of the vial, the infusion bag, and the adaptor in the horizontal direction and/or the vertical direction.
Optionally, the dispensing device according to the present invention further includes a shaking mechanism disposed on the base plate, and the shaking mechanism is connected to the clamping assembly of the medicine bottle and adapted to drive the clamping assembly of the medicine bottle to shake so as to shake the medicine bottle.
Optionally, in the dispensing device according to the present invention, at least two recycling cases are further included, the at least two recycling cases being used for recycling the vial and the adapter, respectively.
According to another aspect of the invention, an adapter is provided, which comprises a base and two channels penetrating through the base, wherein the first channel is linear, one end of the first channel is connected to a medicine bottle, and the other end of the first channel is connected to an infusion bag; the second channel is in a zigzag shape, one end of the second channel is connected to the medicine bottle, the other end of the second channel is connected to a pressure adjusting assembly of the medicine dispensing device, and the pressure adjusting assembly is suitable for adjusting air pressure in the medicine bottle.
Optionally, in the adaptor according to the present invention, both ends of the first channel and the second channel are exposed to the base, and a length of the connection end of the first channel and the medicine bottle exposed to the base is greater than a length of the connection end of the second channel and the medicine bottle exposed to the base.
Optionally, in the adaptor according to the present invention, both ends of the first channel and one end of the second channel connected to the medicine bottle are sharp-shaped.
Optionally, in the adaptor according to the present invention, one end of the second channel is connected to the pressure regulating assembly through a conduit.
According to a further aspect of the present invention, there is provided a dispensing method adapted to be carried out in the dispensing apparatus described above, the method comprising: the medicine bottle, the infusion bag and the adapter are respectively fixed on the dispensing device, and the medicine bottle and the adapter, the infusion bag and the adapter are respectively connected with the pressure regulating component; adjusting the positions of the medicine bottle and the infusion bag to enable the infusion bag to be positioned right above the medicine bottle; the pressure regulating component is regulated to generate negative pressure in the medicine bottle, and the liquid medicine in the infusion bag flows into the medicine bottle through the adapter; shaking the medicine bottle to dissolve the medicine powder in the medicine bottle into the medicine liquid; adjusting the positions of the medicine bottle and the infusion bag to ensure that the medicine bottle is positioned right above the infusion bag; the pressure adjusting component is adjusted to generate positive pressure in the medicine bottle, and the medicine liquid in the medicine bottle flows into the infusion bag through the adapter.
Optionally, in the dispensing method according to the present invention, the adapter includes a base and two channels penetrating through the base, wherein the first channel is linear and the second channel is polygonal; the pressure adjusting assembly comprises a cavity, a piston piece arranged in the cavity and a motion mechanism connected with the piston piece; the step of being connected medicine bottle and adapter, infusion bag and adapter, adapter and pressure adjustment subassembly respectively includes: and respectively connecting a medicine bottle to one end of the first channel and one end of the second channel, connecting an infusion bag to the other end of the first channel, and connecting the other end of the second channel to the cavity.
Alternatively, in the dispensing method according to the present invention, the step of adjusting the pressure regulating assembly to generate negative pressure in the medicine bottle comprises: and adjusting the movement mechanism to enable the piston piece to do linear movement in the cavity along the direction away from the connecting end of the cavity and the second channel, so that negative pressure is generated in the medicine bottle.
Optionally, in the dispensing method according to the present invention, the step of adjusting the pressure regulating assembly to generate positive pressure in the vial comprises: and adjusting the movement mechanism to enable the piston piece to do linear motion in the cavity along the direction close to the connecting end of the cavity and the second channel, so that positive pressure is generated in the medicine bottle.
Optionally, in the dispensing method according to the present invention, after the step of adjusting the pressure adjustment assembly to generate positive pressure in the medicine bottle, the medicine liquid in the medicine bottle flows into the infusion bag through the adapter, the method further includes: and respectively disconnecting the medicine bottle from the adapter, the infusion bag from the adapter, and the adapter from the pressure regulating assembly, and respectively disconnecting the medicine bottle from the infusion bag from the adapter and from the dispensing device.
Optionally, in the dispensing method according to the present invention, the dispensing device further includes a recycling bin, and the step of disconnecting the vial, the infusion bag, and the adapter from the dispensing device further includes: the positions of the medicine bottle and the adapter are respectively adjusted to be right above the recovery box, and the connection between the medicine bottle and the adapter and the dispensing device is respectively disconnected.
According to the technical scheme of the invention, the relative positions of the medicine bottle and the infusion bag in the vertical direction are adjusted through the rotating component, and the air pressure in the medicine bottle is adjusted through the pressure adjusting component, so that the medicine powder in the medicine bottle and the liquid medicine in the infusion bag can be mixed. The technical scheme of the invention realizes automation and convenience of the dispensing process, reduces the labor intensity of medical personnel, and has high dispensing efficiency and safe and reliable dispensing process.
The foregoing description is only an overview of the technical solutions of the present invention, and the embodiments of the present invention are described below in order to make the technical means of the present invention more clearly understood and to make the above and other objects, features, and advantages of the present invention more clearly understandable.
Drawings
To the accomplishment of the foregoing and related ends, certain illustrative aspects are described herein in connection with the following description and the annexed drawings, which are indicative of various ways in which the principles disclosed herein may be practiced, and all aspects and equivalents thereof are intended to be within the scope of the claimed subject matter. The above and other objects, features and advantages of the present disclosure will become more apparent from the following detailed description read in conjunction with the accompanying drawings. Throughout this disclosure, like reference numerals generally refer to like parts or elements.
FIGS. 1 and 2 show front and back isometric views, respectively, of a dispensing device 100 according to an embodiment of the present invention;
FIGS. 3, 4 show front and left side views, respectively, of the dispensing device 100 at A of FIG. 1;
FIGS. 5 and 6 show a right side view and a top view, respectively, of the dispensing device 100 at B of FIG. 2;
FIG. 7 illustrates a cross-sectional view of an adapter 200 according to one embodiment of the present invention;
FIG. 8 illustrates a flow diagram of a method 800 of dispensing medication according to one embodiment of the present invention;
fig. 9A-9E show schematic diagrams of an implementation of the dispensing method 800.
Detailed Description
Exemplary embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. While exemplary embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure may be embodied in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art.
Fig. 1, 2 show a front isometric view and a back isometric view, respectively, of a dispensing device 100 according to an embodiment of the present invention. The dispensing device 100 may mix the medicine powder in the medicine bottle 300 and the medicine liquid in the infusion bag 400 to complete dispensing. Vial 300 may be, for example, a vial of penicillin. It should be noted that the vial 300 and the bag 400 are not intrinsic to the dispensing device 100, but are fixed to the dispensing device 100 as foreign objects.
As shown in fig. 1 and 2, the apparatus 100 includes a base 110 and various components disposed on the base 110, wherein components such as a rotating assembly 120, a substrate 130, a clamping assembly 140, and the like are disposed at a position a in fig. 1, a pressure adjusting assembly 150 is disposed at a position B in fig. 2, details at a position a in fig. 1 are shown in fig. 3 and 4, and details at B position B in fig. 2 are shown in fig. 5 and 6.
As shown in fig. 1, 3 and 4, the base 110 is provided with a rotating assembly 120, the rotating assembly 120 is connected to the base plate 130, the base plate 130 is provided with a clamping assembly 140, and the clamping assembly 140 is used for fixing the medicine bottle 300, the infusion bag 400 and the adapter 200. The adapter 200 may be connected to the vial 300 and the infusion bag 400, respectively, to establish a fluid communication path between the vial 300 and the infusion bag 400, thereby facilitating mixing of the drug powder in the vial 300 with the fluid in the infusion bag 400. It should be noted that the adapter 200 is not an intrinsic component of the dispensing device 100, but rather is affixed to the dispensing device 100 as an external object. When the dispensing device 100 dispenses the medicament, the clamping component 140, the adaptor 200, the medicine bottle 300 and the infusion bag 400 are all located on the substrate 130, the substrate 130 is connected with the rotating component 120, and the rotating component 120 can drive the substrate 130 to rotate, so that the clamping component 140, the adaptor 200, the medicine bottle 300 and the infusion bag 400 on the substrate 130 are driven to rotate together.
It should be noted that the dispensing device 100 includes a plurality of holding assemblies 140, for example, as shown in fig. 3, the holding assembly 140-1 is used for holding the vial 300, and the holding assembly 140-2 is used for holding the infusion bag 400, and the invention is not limited to the number of holding assemblies 140 included in the dispensing device 100. Of course, according to an embodiment, in order to firmly fix the medicine bottle 300, the infusion bag 400 and the adapter 200, the medicine bottle 300, the infusion bag 400 and the adapter 200 may respectively correspond to a plurality of clamping assemblies 140, for example, one clamping assembly 140 may be respectively arranged at the upper part and the lower part of the infusion bag 400.
According to one embodiment, a translation assembly 170 is further disposed on the base plate 130, and the translation assembly 170 is connected to the holding assembly 140 for adjusting the position of the holding assembly 140 in the horizontal direction and/or the vertical direction and/or the inside-outside direction (which may be understood as the x-axis direction, the y-axis direction, and the Z-axis direction), so as to adjust the position of the medicine bottle 300, the infusion bag 400, and the adaptor 200 in the horizontal direction and/or the vertical direction and/or the inside-outside direction. It should be noted that one or more translation assemblies 170 may be included in the dispensing device 100, each translation assembly 170 corresponding to movement of an object (vial 300, bag 400, or adapter 200) in one direction (horizontal, vertical, or in-out), i.e., the number of translation assemblies 170 is determined by the number of moveable directions of the vial 300, bag 400, and adapter 200. For example, if vial 300 is movable in three directions, i.e., horizontal, vertical, and inside-out, then vial 300 requires three translation assemblies 170, e.g., as shown in fig. 3 and 4, translation assemblies 170-1, 170-2, and 170-3 are used to control the movement of vial 300 in the horizontal, vertical, and inside-out directions, respectively; the bag 400 may be moved in a vertical direction, and the bag 400 may require a translation assembly 170, e.g., as shown in fig. 3 and 4, the translation assembly 170-4 may be used to control the movement of the bag 400 in the vertical direction; the adaptor 200 can move in the inside-out direction, and the adaptor 200 requires only one translation assembly 170. The present invention does not limit the number of translation assemblies 170 included in the dispensing device 100.
According to an embodiment, a shaking mechanism 180 is further disposed on the base plate 130 (the shaking mechanism 180 is not shown in fig. 3 and 4), and the shaking mechanism 180 is connected to the clamping assembly 140 for fixing the medicine bottle 300, and can drive the clamping assembly 140 of the medicine bottle 300 to shake, so as to shake the medicine bottle 300. After the liquid medicine in the infusion bag 400 enters the medicine bottle 300, the shaking mechanism 180 shakes the medicine bottle 300, so that the medicine powder in the medicine bottle 300 is rapidly dissolved in the liquid medicine.
As shown in fig. 2, 5 and 6, a pressure regulating assembly 150 is disposed on the base 110, and the pressure regulating assembly 150 includes a cavity 152, a piston member 154 disposed in the cavity 152, and a moving mechanism 156 connected to the piston member 154. One end of the cavity 152 is connected to the adapter 200, and the adapter 200 is connected to the vial 300. According to one embodiment, lumen 152 is connected to adapter 200 via conduit 160, with adapter 200 being located at C in fig. 5, 6 (adapter 200 not shown in fig. 5, 6). The conduit 160 may be, for example, but not limited to, a hose of glue. The piston 154 is driven by the moving mechanism 156 to reciprocate linearly in the cavity 152, so as to discharge the air in the cavity 152 to the medicine bottle 300, generate positive pressure in the medicine bottle 300, and discharge the medicine liquid in the medicine bottle 300 to the infusion bag 400; or air in the medicine bottle 300 is sucked into the cavity 152, so that negative pressure is generated in the medicine bottle 300, and the medicine liquid in the infusion bag 400 flows into the medicine bottle 300.
According to one embodiment, the dispensing device 100 further comprises at least two recovery boxes for recovering the vial and the adapter, respectively. For example, as shown in fig. 1 and 2, the dispensing device 100 includes two recovery boxes 190 for recovering a vial 300 and an adapter 200 for completing dispensing, respectively.
Fig. 7 shows a cross-sectional view of an adapter 200 according to an embodiment of the invention. As shown in fig. 7, the adapter 200 includes a base 210 and two passages 220, 230 extending through the base 210. The first channel 220 is a linear channel having one end 222 connected to the vial 300 and the other end 224 connected to the bag 400, and the first channel 220 is a fluid channel for communicating a liquid medicine between the vial 300 and the bag 400. The second channel 230 is in the form of a dogleg, one end 232 of which is connected to the vial 300 and the other end 234 of which is connected to the pressure regulating assembly 150 of the dispensing device 100, and more particularly, with reference to fig. 5 and 6, the port 234 is connected to one end of the chamber 152 by a conduit 160. The second passage 230 is a gas passage, and the pressure regulating assembly 150 regulates the gas pressure in the medicine bottle 300 through the second passage 230, thereby controlling the flow direction of the medicine in the first passage 220.
According to an embodiment, the two ends 222, 224 of the first channel 220 and the two ends 232, 234 of the second channel 230 are exposed out of the base 210, and the length of the connection end 222 of the first channel 220 and the vial 300 exposed out of the base 210 is greater than the length of the connection end 232 of the second channel 230 and the vial 300 exposed out of the base 210, that is, in fig. 7, the length of the section D is greater than the length of the section E, so that when a negative pressure is generated in the vial 300, only the port 222 may contact the liquid medicine in the vial 300, and the port 232 does not contact the liquid medicine in the vial 300, thereby preventing the liquid medicine in the vial 300 from flowing into the pressure regulating assembly 150 (i.e., the cavity 152) of the dispensing device 100 through the second channel 230.
According to one embodiment, the two ends 222, 224 of the first channel 220 and the end 232 of the second channel 230 connected to the vial 300 are sharp, so as to facilitate the first channel 220 and the second channel 230 to pierce the sealing cap (usually rubber material) of the vial 300 and the infusion bag 400 and enter the interior of the vial 300 and the infusion bag 400.
FIG. 8 illustrates a flow diagram of a dispensing method 800 according to one embodiment of the present invention, the method 800 may be implemented in a dispensing device (e.g., the dispensing device 100 described above). As shown in fig. 8, method 800 begins at step S810.
In step S810, the medicine bottle, the infusion bag, and the adapter are respectively fixed to the dispensing device, and the medicine bottle and the adapter, the infusion bag and the adapter, and the adapter and the pressure adjustment assembly are respectively connected. According to an embodiment, referring to fig. 3 and 4, the step S810 corresponds to fixing the vial 300, the infusion bag 400 and the adaptor 200 on the dispensing device 100 by the clamping assembly 140, and adjusting the positions of the vial 300, the infusion bag 400 and the adaptor 200 by the translation assembly 170, so that the vial 300 is connected to the adaptor 200, the infusion bag 400 is connected to the adaptor 200, and the adaptor 200 is connected to the pressure regulating assembly 150. More specifically, according to one embodiment, referring to fig. 5-7, the vial and adapter, the bag and adapter, and the adapter and the pressure regulating assembly are connected, i.e., the vial 300 is connected to the port 222 of the first channel 220 and the port 232 of the second channel 230, the bag 400 is connected to the port 224 of the first channel 220, and the bag 234 is connected to the cavity 152.
Subsequently, in step S820, the positions of the vial and the infusion bag are adjusted so that the infusion bag is positioned directly above the vial. According to an embodiment, referring to fig. 3 and 4, the step S820 corresponds to adjusting the rotation assembly 120 to rotate the substrate 130, rotating the medicine bottle 300, the infusion bag 400, the adaptor 200, the clamping assembly 140, and the like on the substrate 130 together, and stopping adjusting the rotation assembly 120 when the infusion bag 400 is positioned right above the medicine bottle 300.
Subsequently, in step S830, the pressure regulating assembly is adjusted to generate a negative pressure in the medicine bottle, and the medicine liquid in the infusion bag flows into the medicine bottle through the adapter. Referring to fig. 5-7, step S830 further includes, according to one embodiment: the moving mechanism 156 is adjusted to move the piston member 154 linearly in the cavity 152 in a direction away from the connecting end of the cavity 152 and the second channel (for fig. 5, the piston member 154 is moved downward in the cavity 152), so that air in the medicine bottle 300 is sucked into the cavity 152, a negative pressure is generated in the medicine bottle 300, and the medicine liquid in the infusion bag 400 flows into the medicine bottle 300.
Subsequently, in step S840, the medicine bottle is shaken to dissolve the medicine powder in the medicine bottle in the medicine liquid. According to one embodiment, step S840 corresponds to the shaking mechanism 180 on the dispensing device 100 shaking the vial 300.
Subsequently, in step S850, the positions of the vial and the infusion bag are adjusted so that the vial is positioned directly above the infusion bag. According to an embodiment, referring to fig. 3 and 4, the step S850 corresponds to adjusting the rotation assembly 120 to rotate the substrate 130, rotating the vial 300, the infusion bag 400, the adapter 200, the clamping assembly 140, and the like on the substrate 130 together, and stopping adjusting the rotation assembly 120 until the vial 300 is positioned right above the infusion bag 400.
Subsequently, in step S860, the pressure regulating assembly is adjusted to generate a positive pressure in the vial, and the medical fluid in the vial flows into the infusion bag via the adapter. According to an embodiment, referring to fig. 5-7, step S860 further comprises: the moving mechanism 156 is adjusted to move the piston member 154 linearly in the cavity 152 in a direction close to the connecting end of the cavity 152 and the second channel (for fig. 5, the piston member 154 is moved upward in the cavity 152), so that air in the cavity 152 is discharged into the medicine bottle 300, a positive pressure is generated in the medicine bottle 300, and the medicine liquid in the medicine bottle 300 flows into the infusion bag 400.
According to an embodiment, after step S860, step S870 is further included (step S870 is not shown in fig. 8). In step S870, the connection between the drug bottle and the adapter, the connection between the infusion bag and the adapter, and the connection between the adapter and the pressure regulating assembly are respectively disconnected, and the connection between the drug bottle, the infusion bag, and the adapter and the dispensing device are respectively disconnected. According to an embodiment, referring to fig. 3 and 4, the step S870 corresponds to adjusting the positions of the vial 300, the infusion bag 400 and the adapter 200 by the translation assembly 170, so as to disconnect the vial 300 from the adapter 200, the infusion bag 400 from the adapter 200, and the adapter 200 from the pressure regulating assembly 150. Further, the clamping unit 140 is adjusted such that the clamping unit 140 releases the vial 300, the infusion bag 400, and the adaptor 200, thereby disconnecting the vial 300, the infusion bag 400, and the adaptor 200 from the dispensing device 100. Further, in order to conveniently recover the vial 300 and the adapter 200, before the vial 300 and the infusion bag 400 are disconnected from the dispensing device 100, the translation assembly 170 is used to adjust the positions of the vial 300 and the adapter 200 to be respectively right above the recovery box 190, and then the clamping assembly 140 is adjusted to disconnect the vial 300, the adapter 200 and the dispensing device 100. In this way, the vial 300 and the adapter 200 may fall into the recovery bin 190 below after being disconnected from the dispensing device 100, thereby completing the recovery of the vial 300 and the adapter 200.
Fig. 9A-9E further illustrate schematic diagrams of an implementation of the dispensing method 800. For ease of illustration and understanding of the principles of the method 800, FIGS. 9A-9E provide some simplification in the construction of the dispensing device 100. Only the chamber 152, piston member 154 and recovery tank 190 of the dispensing device 100 are shown in fig. 9A-9E, and other components, such as the base 110, rotating assembly 120, base plate 130, etc., are not shown in fig. 9A-9E. Furthermore, to reduce the size of the drawings, the conduit 160 is not shown in fig. 9A-9E, but rather the cavity 152 is depicted as being directly connected to the adapter 200.
In fig. 9A, the adaptor 200, vial 300, infusion bag 400, and chamber 152 are not yet connected to each other. Subsequently, as shown in fig. 9B, the adaptor 200 is connected to the vial 300, the infusion bag 400, and the cavity 152, respectively, and the position of the infusion bag 400 is adjusted to be right above the vial 300. The piston member 154 moves linearly (i.e., moves rightward) in a direction away from the connection end of the cavity 152 and the adaptor 200, air in the vial 300 is sucked into the cavity 152 along the second passage 230, a negative pressure is generated in the vial 300, and the liquid medicine in the infusion bag 400 flows into the vial 300 along the first passage 220. Subsequently, as shown in fig. 9C, the medicine bottle 300 is shaken to sufficiently dissolve the medicine powder in the medicine bottle 300 into the medicine liquid. Subsequently, as shown in fig. 9D, the positions of the vial 300 and the infusion bag 400 are adjusted so that the vial 300 is positioned directly above the infusion bag 400. The piston member 154 moves linearly (i.e., leftwardly) in a direction close to the connection end of the cavity 152 and the adaptor 200, air in the cavity 152 is discharged into the vial 300 along the second passage 230, positive pressure is generated in the vial 300, and the liquid medicine in the vial 300 flows into the infusion bag 400 along the first passage 220. After the liquid medicine in the medicine bottle 300 completely flows into the infusion bag 400, the dispensing is completed. Subsequently, as shown in fig. 9E, the positions of the vial 300 and the adapter 200 are adjusted to be right above the recovery box 190, the vial 300 and the adapter 200 are disconnected from the dispensing device 100, and the vial 300 and the adapter 200 are dropped into the respective recovery boxes 190, thereby completing the recovery of the vial 300 and the adapter 200.
The adapter of B10: B9, wherein both ends of the first channel and one end of the second channel connected to the medicine bottle are sharp.
The adapter of any one of B11: B8-10, wherein one end of the second channel is connected to the pressure regulating assembly by a conduit.
The method of C13: C12, wherein the adapter comprises a base and two channels penetrating through the base, wherein the first channel is linear and the second channel is zigzag; the pressure adjusting assembly comprises a cavity, a piston piece arranged in the cavity and a motion mechanism connected with the piston piece;
the step of being connected medicine bottle and adapter, infusion bag and adapter, adapter and pressure adjustment subassembly respectively includes: and respectively connecting a medicine bottle to one end of the first channel and one end of the second channel, connecting an infusion bag to the other end of the first channel, and connecting the other end of the second channel to the cavity.
The method of C14: C13, wherein the step of adjusting the pressure adjustment assembly to create negative pressure in the vial comprises: and adjusting the movement mechanism to enable the piston piece to do linear movement in the cavity along the direction away from the connecting end of the cavity and the second channel, so that negative pressure is generated in the medicine bottle.
The method of C15: C13 or 14, wherein the step of adjusting the pressure adjustment assembly to create positive pressure in the vial comprises: and adjusting the movement mechanism to enable the piston piece to do linear motion in the cavity along the direction close to the connecting end of the cavity and the second channel, so that positive pressure is generated in the medicine bottle.
The method according to any of the preceding claims C16 to C12-15, further comprising, after the step of adjusting the pressure adjustment assembly to generate a positive pressure in the vial and flowing the medical fluid in the vial into the infusion bag via the adapter: and respectively disconnecting the medicine bottle from the adapter, the infusion bag from the adapter, and the adapter from the pressure regulating assembly, and respectively disconnecting the medicine bottle from the infusion bag from the adapter and from the dispensing device.
The method of C17: C16, wherein the dispensing device further comprises a recycling bin, and the step of disconnecting the vial, the infusion bag, the adapter, and the dispensing device respectively further comprises: the positions of the medicine bottle and the adapter are respectively adjusted to be right above the recovery box, and the connection between the medicine bottle and the adapter and the dispensing device is respectively disconnected.
In the description provided herein, numerous specific details are set forth. It is understood, however, that embodiments of the invention may be practiced without these specific details. In some instances, well-known methods, structures and techniques have not been shown in detail in order not to obscure an understanding of this description.
Similarly, it should be appreciated that in the foregoing description of exemplary embodiments of the invention, various features of the invention are sometimes grouped together in a single embodiment, figure, or description thereof for the purpose of streamlining the disclosure and aiding in the understanding of one or more of the various inventive aspects. However, the disclosed method should not be interpreted as reflecting an intention that: that the invention as claimed requires more features than are expressly recited in each claim. Rather, as the following claims reflect, inventive aspects lie in less than all features of a single foregoing disclosed embodiment. Thus, the claims following the detailed description are hereby expressly incorporated into this detailed description, with each claim standing on its own as a separate embodiment of this invention.
Those skilled in the art will appreciate that the modules or units or components of the devices in the examples disclosed herein may be arranged in a device as described in this embodiment or alternatively may be located in one or more devices different from the devices in this example. The modules in the foregoing examples may be combined into one module or may be further divided into multiple sub-modules.
Those skilled in the art will appreciate that the modules in the device in an embodiment may be adaptively changed and disposed in one or more devices different from the embodiment. The modules or units or components of the embodiments may be combined into one module or unit or component, and furthermore they may be divided into a plurality of sub-modules or sub-units or sub-components. All of the features disclosed in this specification (including any accompanying claims, abstract and drawings), and all of the processes or elements of any method or apparatus so disclosed, may be combined in any combination, except combinations where at least some of such features and/or processes or elements are mutually exclusive. Each feature disclosed in this specification (including any accompanying claims, abstract and drawings) may be replaced by alternative features serving the same, equivalent or similar purpose, unless expressly stated otherwise.
Furthermore, those skilled in the art will appreciate that while some embodiments described herein include some features included in other embodiments, rather than other features, combinations of features of different embodiments are meant to be within the scope of the invention and form different embodiments. For example, in the following claims, any of the claimed embodiments may be used in any combination.
As used herein, unless otherwise specified the use of the ordinal adjectives "first", "second", "third", etc., to describe a common object, merely indicate that different instances of like objects are being referred to, and are not intended to imply that the objects so described must be in a given sequence, either temporally, spatially, in ranking, or in any other manner.
While the invention has been described with respect to a limited number of embodiments, those skilled in the art, having benefit of this description, will appreciate that other embodiments can be devised which do not depart from the scope of the invention as described herein. Furthermore, it should be noted that the language used in the specification has been principally selected for readability and instructional purposes, and may not have been selected to delineate or circumscribe the inventive subject matter. Accordingly, many modifications and variations will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the appended claims. The present invention has been disclosed in an illustrative rather than a restrictive sense with respect to the scope of the invention, as defined in the appended claims.

Claims (13)

1. A dispensing device adapted to mix a drug powder in a drug vial with a drug solution in an infusion bag to complete a dispensing, the device comprising:
a base;
the rotating assembly is arranged on the base;
the base plate is connected with the rotating assembly;
the clamping component is arranged on the substrate and is suitable for fixing the medicine bottle, the infusion bag and the adapter, and the adapter is suitable for being connected with the medicine bottle and the infusion bag respectively;
the base plate is suitable for being driven by the rotating component to rotate, and the clamping component, the adapter, the medicine bottle and the infusion bag on the base plate are driven to rotate together, so that the relative positions of the medicine bottle and the infusion bag in the vertical direction are adjusted;
the adapter comprises a base body and two channels penetrating through the base body, wherein the first channel is linear, one end of the first channel is connected to the medicine bottle, and the other end of the first channel is connected to the infusion bag; the second channel is in a fold line shape, one end of the second channel is connected to the medicine bottle, and the other end of the second channel is connected to a pressure adjusting component of the medicine dispensing device;
the pressure adjusting assembly is arranged on the base, connected with the adapter and suitable for adjusting air pressure in the medicine bottle.
2. The device of claim 1, wherein the pressure regulating assembly comprises a chamber, a piston member disposed in the chamber, and a movement mechanism coupled to the piston member, one end of the chamber being coupled to the adapter,
the piston piece is suitable for being driven by the motion mechanism to do linear reciprocating motion in the cavity, so that the air pressure in the medicine bottle is adjusted.
3. The device of claim 2, wherein one end of the lumen is connected to the adapter by a conduit.
4. The device of claim 3, wherein the conduit is a flexible hose of gum.
5. The device according to any one of claims 1 to 4, further comprising a translation assembly disposed on the base plate, the translation assembly being connected to the clamping assembly and adapted to adjust the position of the clamping assembly in the horizontal direction and/or the vertical direction so as to adjust the position of the vial, infusion bag, adaptor in the horizontal direction and/or the vertical direction.
6. The apparatus of claim 1, further comprising a shaking mechanism disposed on the base plate, the shaking mechanism being coupled to the vial clamping assembly and adapted to shake the vial clamping assembly to thereby shake the vial.
7. The apparatus of claim 1, further comprising at least two recycling bins for recycling the vial and the adapter, respectively.
8. A dispensing method adapted to be performed in a dispensing device according to any of claims 1-7, the method comprising:
the medicine bottle, the infusion bag and the adapter are respectively fixed on the dispensing device, and the medicine bottle and the adapter, the infusion bag and the adapter are respectively connected with the pressure regulating component;
adjusting the positions of the medicine bottle and the infusion bag to enable the infusion bag to be positioned right above the medicine bottle;
the pressure regulating component is regulated to generate negative pressure in the medicine bottle, and the liquid medicine in the infusion bag flows into the medicine bottle through the adapter;
shaking the medicine bottle to dissolve the medicine powder in the medicine bottle into the medicine liquid;
adjusting the positions of the medicine bottle and the infusion bag to ensure that the medicine bottle is positioned right above the infusion bag;
the pressure adjusting component is adjusted to generate positive pressure in the medicine bottle, and the medicine liquid in the medicine bottle flows into the infusion bag through the adapter.
9. The method of claim 8, wherein the adapter comprises a base and two channels extending through the base, wherein a first channel is linear and a second channel is dogleg; the pressure adjusting assembly comprises a cavity, a piston piece arranged in the cavity and a motion mechanism connected with the piston piece;
the step of being connected medicine bottle and adapter, infusion bag and adapter, adapter and pressure adjustment subassembly respectively includes: and respectively connecting a medicine bottle to one end of the first channel and one end of the second channel, connecting an infusion bag to the other end of the first channel, and connecting the other end of the second channel to the cavity.
10. The method of claim 9, wherein the step of adjusting the pressure regulating assembly to create a negative pressure in the vial comprises: and adjusting the movement mechanism to enable the piston piece to do linear movement in the cavity along the direction away from the connecting end of the cavity and the second channel, so that negative pressure is generated in the medicine bottle.
11. The method of claim 9, wherein the step of adjusting the pressure adjustment assembly to create a positive pressure in the vial comprises: and adjusting the movement mechanism to enable the piston piece to do linear motion in the cavity along the direction close to the connecting end of the cavity and the second channel, so that positive pressure is generated in the medicine bottle.
12. The method of claim 8, wherein after the step of adjusting the pressure adjustment assembly to generate positive pressure in the vial and flowing the medical fluid in the vial into the infusion bag via the adapter, further comprising: and respectively disconnecting the medicine bottle from the adapter, the infusion bag from the adapter, and the adapter from the pressure regulating assembly, and respectively disconnecting the medicine bottle from the infusion bag from the adapter and from the dispensing device.
13. The method of claim 12, wherein the dispensing device further comprises a recovery tank, and the step of disconnecting the vial, the infusion bag, and the adapter from the dispensing device, respectively, further comprises: the positions of the medicine bottle and the adapter are respectively adjusted to be right above the recovery box, and the connection between the medicine bottle and the adapter and the dispensing device is respectively disconnected.
CN201810059487.9A 2018-01-22 2018-01-22 Dispensing device, adapter and dispensing method Active CN107997961B (en)

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