CN107992007A - One kind digitlization tomographic system - Google Patents
One kind digitlization tomographic system Download PDFInfo
- Publication number
- CN107992007A CN107992007A CN201711261496.8A CN201711261496A CN107992007A CN 107992007 A CN107992007 A CN 107992007A CN 201711261496 A CN201711261496 A CN 201711261496A CN 107992007 A CN107992007 A CN 107992007A
- Authority
- CN
- China
- Prior art keywords
- communication
- control unit
- digitlization
- instrument
- modules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004891 communication Methods 0.000 claims abstract description 34
- 238000005516 engineering process Methods 0.000 claims abstract description 13
- 239000007788 liquid Substances 0.000 claims abstract description 8
- 238000000746 purification Methods 0.000 claims abstract description 4
- 238000004587 chromatography analysis Methods 0.000 claims description 8
- 238000001514 detection method Methods 0.000 claims description 3
- 239000000243 solution Substances 0.000 abstract description 8
- 239000007864 aqueous solution Substances 0.000 abstract description 2
- 229960000074 biopharmaceutical Drugs 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 230000008569 process Effects 0.000 description 3
- 230000008859 change Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012827 research and development Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000011897 real-time detection Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000008054 signal transmission Effects 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B19/00—Programme-control systems
- G05B19/02—Programme-control systems electric
- G05B19/418—Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control [DNC], flexible manufacturing systems [FMS], integrated manufacturing systems [IMS] or computer integrated manufacturing [CIM]
- G05B19/4183—Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control [DNC], flexible manufacturing systems [FMS], integrated manufacturing systems [IMS] or computer integrated manufacturing [CIM] characterised by data acquisition, e.g. workpiece identification
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P90/00—Enabling technologies with a potential contribution to greenhouse gas [GHG] emissions mitigation
- Y02P90/02—Total factory control, e.g. smart factories, flexible manufacturing systems [FMS] or integrated manufacturing systems [IMS]
Landscapes
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Manufacturing & Machinery (AREA)
- Quality & Reliability (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Automation & Control Theory (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Abstract
The invention discloses one kind to digitize tomographic system, it is made of central control unit, communication module, data-converting block and chromatographic apparatus, the chromatographic apparatus is full-automatic purification system, and the chromatographic apparatus includes UV detectors, diaphragm pump, pressure detector, flow detector, pH and Conductivity detectors and liquid level detector and automatic valve；The present invention is configured with RS485 communication modules, RS232 modules and ProfibusDP far modules；The communication module directly carries out digital communication, reading or write-in correlation values with instrument；The common analog signal instrument in scene is converted into digital signal by the data-converting block, is sent to by digital communication technology in control unit；Described control unit and the digital Communication Control of instrument, after digitized communication, improve the decay of original technology analog signal, simulating signal interference, install the problems such as circuit is cumbersome.Aqueous solution and the bigger solution of viscosity can be effectively differentiated by IOLink sensors.
Description
Technical field
The present invention relates to a kind of device of biopharmaceutical technology, is specifically that one kind realizes digitized chromatography system
System.
Background technology
In recent years, as the continuous of bio-pharmaceutical industry competition aggravates, M＆A integration and money between macro-organism pharmacy corporation
This running is increased, and domestic outstanding bio-pharmaceuticals manufacturing enterprise more and more payes attention to the research to industry market, particularly pair
The further investigation of Business Development Environment and customer demand Long-term change trend.
Technical elements, which are broken through, accelerates biotechnology in the application of pharmaceutical field and the research and development of new drug, and global pharmacy giant is
This emerging field of bio-pharmaceuticals has been aimed at, has fallen over each other to develop biological medicine market.And also there are some well-known medicine enterprises in China at present
Also begin to march biomedicine field.Technological innovation is the foundation stone of modern enterprise survival and development, interprise's intensive management and research and development
The input of expense, be determine enterprise competitiveness, improve Business Economic Benefit key factor, the growth to enterprise have act foot it is light
The effect of weight.
At present, in field of biological pharmacy, chromatography isolation technics is the main partition method of bio-pharmaceuticals.Traditional chromatography
System is to connect valve, delivery pump, bubble trap, pressure sensor, flow sensor with chromatographic column and UV detector
State together, can provide power simultaneously can real-time detection process data in process of production.But traditional instrument detection
Sensor is all analog signal output, or switching signal output, is vulnerable to electric signal interference and electricity during electric signal transmission
Signal attenuation, causes to lose precision and error, so that can not accurate measurement process data.As digital signal enters, the present invention
Totally digitilized instrument is employed, perfection solves the problems, such as above-mentioned run into.
Existing tomographic system instrument substantially uses the analog electrical signal of traditional type, first, function is single, second, easily by
Signal interference, third, have signal attenuation in transmitting procedure, fourth, collection analog signal module resolution precision not enough causes error,
It can not meet that production process data that user collects and instrument are actually detected completely the same.Meanwhile traditional on-off model
Sensor also can not accurately differentiate aqueous solution and the bigger solution of viscosity.
The content of the invention
It is an object of the invention to provide the full-automatic tomographic system based on a kind of technology by digitized instrument control, match somebody with somebody
RS485 communication modules, RS232 modules and ProfibusDP far modules are put, common electric current, voltage signal are converted into numeral
Communication is delivered in control system, and it is authentic and valid and error free to be allowed to instrumented data, proposed in the above background technology to solve
Problem.
To achieve the above object, the present invention provides following technical solution：
One kind digitlization tomographic system, is made of, institute central control unit, communication module, data-converting block and chromatographic apparatus
It is full-automatic purification system to state chromatographic apparatus, and the chromatographic apparatus includes UV detectors, diaphragm pump, pressure detector, flow
Detector, pH and Conductivity detectors and liquid level detector and automatic valve.
As the further scheme of the present invention：The central control unit, communication module, data-converting block and chromatography dress
Put chromatography control system of the composition based on digital communication technology.
As the further scheme of the present invention：The diaphragm pump, pressure detector, flow detector connect successively in order
Connect, the flow detection end of flow detector is connected with chromatographic column, pH and Conductivity detectors and liquid level detector and
Automatic valve is connected with chromatographic column.
As the further scheme of the present invention：It is long-range to be configured with RS485 communication modules, RS232 modules and ProfibusDP
Module.
As the further scheme of the present invention：The communication module directly carries out digital communication, reading or write-in with instrument
Correlation values.
As the further scheme of the present invention：The common analog signal instrument in scene is converted into by the data-converting block
Digital signal, is sent in control unit by digital communication technology.
As the further scheme of the present invention：Described control unit and the digital Communication Control of instrument.
Compared with prior art, the beneficial effects of the invention are as follows：After digitized communication, original skill is improved
The problems such as decay of art analog signal, simulating signal interference, cumbersome installation circuit.Water can effectively be differentiated by IOLink sensors
Solution and the bigger solution of viscosity.
Brief description of the drawings
Fig. 1 is control structure schematic diagram of the present invention.
In figure：1-UV detectors, 2- diaphragm pumps, 3- pressure detectors, 4- flow detectors, 5-pH and Conductivity
Detector, 6- liquid level detectors and automatic valve.
Embodiment
Below in conjunction with the attached drawing in the embodiment of the present invention, the technical solution in the embodiment of the present invention is carried out clear, complete
Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, those of ordinary skill in the art are obtained every other without making creative work
Embodiment, belongs to the scope of protection of the invention.
Referring to Fig. 1, in the embodiment of the present invention, one kind digitlization tomographic system, by central control unit, communication module,
Data-converting block and chromatographic apparatus composition, the central control unit, communication module, data-converting block and chromatographic apparatus group
Into the chromatography control system based on digital communication technology, chromatographic apparatus is full-automatic purification system, the chromatographic apparatus
Including UV detectors 1, diaphragm pump 2, pressure detector 3, flow detector 4, pH and Conductivity detectors 5 and liquid level
Detector and automatic valve 6.
The diaphragm pump 2, pressure detector 3, flow detector 4 are sequentially connected in order, the flow inspection of flow detector 4
Survey end with chromatographic column to be connected, pH and Conductivity detectors 5 and liquid level detector and automatic valve 6 and chromatographic column phase
Even, in the chromatography production process of biomedicine field, operation result data can be preserved, trueness error is small.
Present invention configuration RS485 communication modules, RS232 modules and ProfibusDP far modules, common electric current, electricity
Pressure signal is converted into digital communication and is delivered in control system, and it is authentic and valid and error free to be allowed to instrumented data.
The central control unit is handled for programme-control.
The communication module can directly carry out digital communication, reading or write-in correlation values with instrument.
The common analog signal instrument in scene can be converted into digital signal by the data-converting block, logical by numeral
Technology transfer is interrogated into control unit.
Described control unit and the digital Communication Control of instrument.
The present invention is configured using modularized design, and user can be according to production it needs to be determined that the quantity and specification of configuration instrument.
The invention is not limited in above-described embodiment, on the basis of technical solution disclosed by the invention, the skill of this area
Art personnel are according to disclosed technology contents, it is not necessary to which performing creative labour can make one to some of which technical characteristic
A little simple modification, equivalent change and modifications, belong in the range of technical solution of the present invention.
, it is necessary to illustrate in the description of this specification, unless otherwise clearly defined and limited, term " setting ",
" connected " and " connection " should be interpreted broadly, for example, it may be being fixedly connected or being detachably connected, or integratedly be connected
Connect；It can be directly connected, can also be indirectly connected by intermediary, can be the connection inside two elements.For this
For the those of ordinary skill in field, the concrete meaning of above-mentioned term in the present invention can be understood with concrete condition.
Claims (7)
1. one kind digitlization tomographic system, is made of central control unit, communication module, data-converting block and chromatographic apparatus,
It is characterized in that, the chromatographic apparatus is full-automatic purification system, the chromatographic apparatus includes UV detectors (1), diaphragm pump
(2), pressure detector (3), flow detector (4), pH and Conductivity detectors (5) and liquid level detector and automatic
Valve (6).
2. a kind of digitlization tomographic system according to claim 1, it is characterised in that the central control unit, communication
Module, data-converting block and chromatographic apparatus form the chromatography control system based on digital communication technology.
3. a kind of digitlization tomographic system according to claim 2, it is characterised in that the diaphragm pump (2), pressure detecting
Device (3), flow detector (4) are sequentially connected in order, and the flow detection end of flow detector (4) is connected with chromatographic column, pH and
Conductivity detectors (5) and liquid level detector and automatic valve (6) are connected with chromatographic column.
A kind of 4. digitlization tomographic system according to claim 1, it is characterised in that be configured with RS485 communication modules,
RS232 modules and ProfibusDP far modules.
5. a kind of digitlization tomographic system according to claim 3, it is characterised in that the communication module is directly and instrument
Carry out digital communication, reading or write-in correlation values.
6. a kind of digitlization tomographic system according to claim 5, it is characterised in that the data-converting block is by scene
Common analog signal instrument is converted into digital signal, is sent to by digital communication technology in control unit.
7. a kind of digitlization tomographic system according to claim 6, it is characterised in that described control unit is total with instrument
Word Communication Control.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711261496.8A CN107992007A (en) | 2017-12-04 | 2017-12-04 | One kind digitlization tomographic system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711261496.8A CN107992007A (en) | 2017-12-04 | 2017-12-04 | One kind digitlization tomographic system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107992007A true CN107992007A (en) | 2018-05-04 |
Family
ID=62035396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711261496.8A Pending CN107992007A (en) | 2017-12-04 | 2017-12-04 | One kind digitlization tomographic system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107992007A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110123631A (en) * | 2019-05-10 | 2019-08-16 | 苏州市海崴生物科技有限公司 | Intelligent digital matches liquid layer analysis system |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101285762A (en) * | 2007-04-11 | 2008-10-15 | 中国科学院电子学研究所 | Multi-parameter immunity-chromatography test strip quantitative determination instrument |
| CN102253015A (en) * | 2011-03-23 | 2011-11-23 | 中国科学院上海光学精密机械研究所 | Embedded immunochromatography fluorescence detection system and detection method |
| CN102258885A (en) * | 2011-05-18 | 2011-11-30 | 中国地质大学（武汉） | Automatic separation system for integrated column chromatography |
| CN202330347U (en) * | 2011-11-16 | 2012-07-11 | 公安部第三研究所 | Inspection tester for liquid contraband based on quasi static capacitance chromatographic technique |
| US20140102947A1 (en) * | 2012-10-12 | 2014-04-17 | Elwha Llc | Radiofrequency particle separator |
| CN204469275U (en) * | 2013-12-18 | 2015-07-15 | 源创精科生物科技(长沙)有限公司 | The full-automatic tomographic system of a kind of list/double pump |
| CN204865081U (en) * | 2015-06-11 | 2015-12-16 | 李桂花 | Industrial liquid chromatogram chromatographic separation system of modularized design |
| CN105445461A (en) * | 2015-12-30 | 2016-03-30 | 天津诺星生物医药科技有限公司 | Cardiovascular and cerebrovascular disease detection system |
-
2017
- 2017-12-04 CN CN201711261496.8A patent/CN107992007A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101285762A (en) * | 2007-04-11 | 2008-10-15 | 中国科学院电子学研究所 | Multi-parameter immunity-chromatography test strip quantitative determination instrument |
| CN102253015A (en) * | 2011-03-23 | 2011-11-23 | 中国科学院上海光学精密机械研究所 | Embedded immunochromatography fluorescence detection system and detection method |
| CN102258885A (en) * | 2011-05-18 | 2011-11-30 | 中国地质大学（武汉） | Automatic separation system for integrated column chromatography |
| CN202330347U (en) * | 2011-11-16 | 2012-07-11 | 公安部第三研究所 | Inspection tester for liquid contraband based on quasi static capacitance chromatographic technique |
| US20140102947A1 (en) * | 2012-10-12 | 2014-04-17 | Elwha Llc | Radiofrequency particle separator |
| CN204469275U (en) * | 2013-12-18 | 2015-07-15 | 源创精科生物科技(长沙)有限公司 | The full-automatic tomographic system of a kind of list/double pump |
| CN204865081U (en) * | 2015-06-11 | 2015-12-16 | 李桂花 | Industrial liquid chromatogram chromatographic separation system of modularized design |
| CN105445461A (en) * | 2015-12-30 | 2016-03-30 | 天津诺星生物医药科技有限公司 | Cardiovascular and cerebrovascular disease detection system |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110123631A (en) * | 2019-05-10 | 2019-08-16 | 苏州市海崴生物科技有限公司 | Intelligent digital matches liquid layer analysis system |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102500253B (en) | Novel device for distributing standard gas | |
| CN204214881U (en) | A kind of automatic quantitative liquid feeder | |
| CN102435250A (en) | Measuring method and implementation device for slope surface runoff | |
| CN206479426U (en) | A kind of upper wireless sediment concentration measuring system of cableway fish lead | |
| CN103932720A (en) | Method and system for measuring urine volume and urine flow rate | |
| CN109387540A (en) | The continuous on-line monitoring system of helium and its monitoring method | |
| CN203949870U (en) | A kind of liquid physical and chemical parameter measurement mechanism based on fluorescence analysis | |
| CN104089933A (en) | Liquid physical and chemical parameter measuring device based on fluorescence analysis | |
| CN204065048U (en) | A kind of anti-penetration wastewater disposal antisludging agent quality assessment test unit | |
| CN107992007A (en) | One kind digitlization tomographic system | |
| CN201072448Y (en) | Multifunctional rain gauge checking system | |
| CN202236656U (en) | Medical injector pump and infusion pump detecting instrument | |
| CN201780286U (en) | Light-operated metering device | |
| CN206311300U (en) | Sample vertical line is layered real-time measurement apparatus | |
| CN202951408U (en) | Novel device for preparing gas by static volume method | |
| CN202512062U (en) | Full-automatic acid value determiner for petroleum products | |
| CN209621305U (en) | A kind of Photoelectric Detection automatic oil-measuring device | |
| CN202266356U (en) | Microcomputer high-precision gauging digital-display oil injection pump test bed | |
| CN107167346A (en) | The vertical parallel sampling device of water sampling | |
| CN208505956U (en) | A kind of device of on-line continuous detection catalyst reaction liquid pH value | |
| CN106986918A (en) | Based on monolithic processor controlled laboratory level protein chromatography system | |
| CN110672677A (en) | On-line fertilizer liquid component detection device and detection method thereof | |
| CN104111104B (en) | A kind of integrated apparatus measured for natural river course water-level high precision | |
| CN204522777U (en) | A kind of hollow fiber film thread water flux on-line measuring device | |
| CN201972909U (en) | Detecting device of planetary spinning metering pump with one inlet and multiple outlets |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180504 |
|
| RJ01 | Rejection of invention patent application after publication |