CN107970140A - 一种含有鳄鱼油的祛疤组合物及其应用 - Google Patents
一种含有鳄鱼油的祛疤组合物及其应用 Download PDFInfo
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Abstract
本发明公开了一种含有鳄鱼油的祛疤组合物及其应用。所述的含有鳄鱼油的祛疤组合物包括以下质量百分比的组分:鳄鱼油1‑10%、积雪草苷0.5‑5%、甘油葡糖苷0.5‑5%。具有清除疤痕组织、促进细胞新生、滋养肌肤,淡化色素的三重护肤效果,长期使用具有良好的淡化疤痕的作用,其添加护肤品常用的基质或载体,可制成面膜、膏霜、啫喱、乳液、精华液、喷雾、爽肤水等化妆品。
Description
技术领域
本发明涉及一种含有鳄鱼油的祛疤组合物及其应用。
背景技术
疤痕是人体皮肤损伤后取代正常皮肤的纤维组织,是正常皮肤组织外观形态和组织病理学改变的统称,也是创伤愈合的必然结果,中医称为“蟹足肿”或“巨痕症”。疤痕不仅破坏了体表美,还可能影响相关组织或器官的功能,更严重者还能导致畸形。随着外人们对自身容貌关注度的增加,皮肤创面修复成为化妆品行业和整形行业关注的热点。
目前对创面愈合后产生的疤痕多采用手术疗法、加压疗法、皮质类固醇注射疗法、放射疗法、冷冻激光疗法、硅凝胶疗法和生物基因疗法等,由于创面愈合机制尚未完全明确,目前尚缺乏疗效明确的产品,因此对创面愈合机制的研究己经成为皮肤科领域和化妆品领域的重要课题。
中国专利CN 201410321621.X公开了一种含黄芪甲苷的祛疤液,含有五倍子、威灵仙、泽兰、牡丹皮、川芎等中药提取液,宣称产品疗效好、见效快,具有标本兼治的效果,愈后不易复发。中国专利CN 201410618822.6公开了一种止痒祛疤涂膜剂,包含成膜材料,芳香剂与促透剂,增塑剂,pH 调节剂,防腐剂,所述涂膜剂既能针对蚊虫叮咬起到快速止痒消肿作用,又能用于皮肤疤痕的消除。
由上述可知,利用动植物来源的天然营养护肤成分在祛疤产品中有重要的意义。基于此,本发明提供了一种与现有技术不同的祛疤组合物,含有鳄鱼油、积雪苷等来源天然的活性成分,具有显著的祛除疤痕效果。
发明内容
基于此,本发明的目的在于提供一种含有鳄鱼油的祛疤组合物。
解决上述技术问题的技术方案如下:
一种祛疤组合物,包括以下质量百分比的组分:鳄鱼油1-10%、积雪草苷0.5-5%、甘油葡糖苷0.5-5%。
进一步的,所述祛疤组合物还包括以下质量百分比的组分:视黄醇1-5%、人参皂甙0.1-2%、神经酰胺3 0.1-1%。
更进一步的,所述祛疤组合物还包括以下质量百分比的组分:乳化剂1.65-4%、保湿剂3.51-24.1%、皮肤调理剂0.3-3.5%、润肤剂10.1-34.5%、增稠剂0.2-0.8%、防腐剂0.3-1.5%。
优选的,所述乳化剂包括以下组分:异硬脂酰乳酸钠1-2%、甘油硬脂酸酯0.5-1%、PEG-100硬脂酸酯0.1-0.5%、月桂醇聚醚-7 0.05-0.5%。
优选的,所述保湿剂包括以下组分:甘油1-10%、1,3-丙二醇1-5%、透明质酸钠0.01-0.1%、糖基海藻糖0.5-3%、甜菜碱0.5-3%。
优选的,所述皮肤调理剂包括以下组分:生育酚乙酸酯0.1-1%、月桂氮卓酮0.1-2%、β-葡聚糖0.5-3%、酵母提取物0.1-0.5%。
优选的,所述润肤剂包括以下组分:鲸蜡硬脂醇1-4%、聚二甲基硅氧烷1-5%、异十六烷5-10%、霍霍巴(SIMMONDSIA CHINENSIS)籽油1-5%、肉豆蔻酸异丙酯1-5%、辛酸/癸酸甘油三酯1-5%、C13-C14异链烷烃0.1-0.5%。
优选的,所述增稠剂包括以下组分:卡波姆0.1-0.3%、聚丙烯酰胺0.1-0.5%。
优选的,所述防腐剂包括以下组分:肉桂(CINNAMOMUM CASSIA)树皮提取物0.1-0.5%、八角茴香(ILLICIUM VERUM)果提取物0.1-0.5%、茵陈蒿(ARTEMISIA CAPILLARIS)提取物0.1-0.5%。
本发明所述的祛疤组合物具有清除疤痕组织、促进细胞新生、滋养肌肤,淡化色素的三重护肤效果,长期使用具有良好的淡化疤痕的作用,其添加护肤品常用的基质或载体,可制成面膜、膏霜、啫喱、乳液、精华液、喷雾、爽肤水等化妆品。优选的,所述化妆品为膏霜。
与现有技术相比,本发明具有以下有益效果:
1、本发明的祛疤组合物是经发明人大量的实验和研究获得的,精选鳄鱼油、积雪草苷、甘油葡糖苷等成分,按照特定的比例进行配伍,并得出其最佳配方组成。本发明所述的祛疤组合物富含的多种功效成分互相调和、协同,可以起到可起到三重护肤效果作用,具有优良的祛疤功效。具体的,本发明所述的祛疤组合物第一方面能够分解、清除、替代已老化、纤维化的无功能的疤痕组织;第二方面建立正常皮肤原位再生复制的生态环境,促进细胞再生功能;第三方面能够营养滋润肌肤,平衡色素,还原肌肤健康态。
2、实践证明,本发明所提供的祛疤组合物连续使用12周能显著淡化皮肤疤痕,且本发明产品可长期使用,无毒副作用,没有发现刺激性。
具体实施方式
下面结合具体实施例对本发明的祛疤组合物作更详细的描述,但本发明的实施方式不限于此。对于未特别注明的工艺参数或条件,可参照常规技术进行。
本发明祛疤组合物所涉及的部分原料简介如下:
鳄鱼油,含有高达70%以上的不饱和脂肪酸,且脂肪酸组成有深海鱼的特点,二十碳五烯酸(EPA)和二十二碳六烯酸(DHA,俗称脑黄金)含量较高;鳄鱼油有防冻伤、抗菌消炎、促进血液循环、滋润营养、舒筋和消除疲劳的功能。
积雪草苷,从植物积雪草中提取获得。积雪草又名印度石莲花,是多年生匍匐草本植物,原产于印度,现广泛分布于世界各地。在印度草药体系中,积雪草在皮肤炎症和创伤愈合方面的传统应用已沿用千年。
甘油葡糖苷,可以从非洲不死草密罗木中提取获得的一种功效物,由一分子的甘油和一分子的葡萄糖缩合反应而成。甘油葡糖苷具有与透明质酸类似的锁水力,还是一种天然细胞激活剂,能够增强细胞新陈代谢,激活再生皮肤细胞,加速胶原蛋白的合成。
视黄醇,又名维生素A,属于脂溶性维生素。视黄醇具有调节表皮及角质层新陈代谢的功效,能减少皮脂溢出而使皮肤有弹性,同时淡化斑点,柔润肌肤,有助于保护表皮,黏膜不受细菌侵害,健康皮肤,预防皮肤癌。
人参皂甙,一种固醇类化合物,三萜皂苷,主要存在于人参属药材中。人参皂甙具有增强机体免疫力,缓解体力抗疲劳及缓解毒素的作用。
神经酰胺3 ,是存在于皮肤的一种脂类,在表皮角质层形成过程中发挥着重要作用,能加强皮肤抗衰老功能,令肌肤保持弹性,光滑细致,减少面部皱纹形成。
实施例1
一种祛疤霜,包含以下质量百分比的组分:
鳄鱼油1%、积雪草苷5%、甘油葡糖苷0.5%、异硬脂酰乳酸钠2%、甘油硬脂酸酯0.5%、PEG-100硬脂酸酯0.5%、月桂醇聚醚-7 0.05%、甘油10%、1,3-丙二醇1%、透明质酸钠0.1%、糖基海藻糖0.5%、β-葡聚糖3%、甜菜碱0.5%、生育酚乙酸酯1%、月桂氮卓酮0.1%、酵母提取物0.5%、鲸蜡硬脂醇1%、聚二甲基硅氧烷5%、异十六烷5%、霍霍巴(SIMMONDSIA CHINENSIS)籽油1%、肉豆蔻酸异丙酯5%、辛酸/癸酸甘油三酯1%、C13-C14异链烷烃0.5%、卡波姆0.1%、聚丙烯酰胺0.5%、肉桂(CINNAMOMUM CASSIA)树皮提取物0.1%、八角茴香(ILLICIUM VERUM)果提取物0.5%、茵陈蒿(ARTEMISIA CAPILLARIS)提取物0.1%、三乙醇胺0.1%、水 余量。
制备方法:
(1)将鳄鱼油、异硬脂酰乳酸钠、甘油硬脂酸酯、PEG-100硬脂酸酯、月桂氮卓酮、鲸蜡硬脂醇、生育酚乙酸酯、聚二甲基硅氧烷、异十六烷、霍霍巴(SIMMONDSIA CHINENSIS)籽油、肉豆蔻酸异丙酯、辛酸/癸酸甘油三酯依次投入油相锅,搅拌下升温到80℃,溶解均匀,制得油相备用;
(2)将甘油、1,3-丙二醇、透明质酸钠、卡波姆预先混匀,投入乳化锅,然后投入水、糖基海藻糖、β-葡聚糖、甜菜碱、甘油葡糖苷,搅拌下升温到85℃,2000rpm均质3分钟,保温30分钟备用;
(3)将油相抽入乳化锅,开启3000rpm均质5-6分钟,然后保温搅拌20分钟;加入三乙醇胺,搅拌均匀;再加入聚丙烯酰胺、C13-C14异链烷烃、月桂醇聚醚-7,开启3000rpm均质2-3分钟,降温到45℃;
(4)加入预先用水溶解好的积雪草苷,以及肉桂(CINNAMOMUM CASSIA)树皮提取物、八角茴香(ILLICIUM VERUM)果提取物、茵陈蒿(ARTEMISIA CAPILLARIS)提取物,搅拌均匀,3000rpm均质1-2分钟,降温到38℃即可出料。
实施例2
一种祛疤霜,包含以下质量百分比的组分:
鳄鱼油10%、积雪草苷0.5%、甘油葡糖苷5%、异硬脂酰乳酸钠1%、甘油硬脂酸酯1%、PEG-100硬脂酸酯0.1%、月桂醇聚醚-7 0.5%、甘油1%、1,3-丙二醇5%、透明质酸钠0.01%、糖基海藻糖3%、β-葡聚糖0.5%、甜菜碱3%、生育酚乙酸酯0.1%、月桂氮卓酮2%、酵母提取物0.1%、鲸蜡硬脂醇4%、聚二甲基硅氧烷1%、异十六烷10%、霍霍巴(SIMMONDSIA CHINENSIS)籽油1%、肉豆蔻酸异丙酯5%、辛酸/癸酸甘油三酯1%、C13-C14异链烷烃0.5%、卡波姆0.1%、聚丙烯酰胺0.5%、肉桂(CINNAMOMUM CASSIA)树皮提取物0.1%、八角茴香(ILLICIUM VERUM)果提取物0.5%、茵陈蒿(ARTEMISIA CAPILLARIS)提取物0.1%、三乙醇胺0.1%、水 余量。
制备方法:同实施例1。
实施例3
一种祛疤霜,包含以下质量百分比的组分:
鳄鱼油5%、积雪草苷3%、甘油葡糖苷2.5%、异硬脂酰乳酸钠1.5%、甘油硬脂酸酯0.7%、PEG-100硬脂酸酯0.25%、月桂醇聚醚-7 0.25%、甘油5%、1,3-丙二醇2.5%、透明质酸钠0.05%、糖基海藻糖2%、β-葡聚糖2%、甜菜碱2%、生育酚乙酸酯0.5%、月桂氮卓酮1%、酵母提取物0.25%、鲸蜡硬脂醇2%、聚二甲基硅氧烷2%、异十六烷8%、霍霍巴(SIMMONDSIA CHINENSIS)籽油2.5%、肉豆蔻酸异丙酯2.5%、辛酸/癸酸甘油三酯2.5%、C13-C14异链烷烃0.3%、卡波姆0.2%、聚丙烯酰胺0.3%、肉桂(CINNAMOMUM CASSIA)树皮提取物0.3%、八角茴香(ILLICIUMVERUM)果提取物0.3%、茵陈蒿(ARTEMISIA CAPILLARIS)提取物0.3%、三乙醇胺0.2%、水 余量。
制备方法:同实施例1。
实施例4
一种祛疤霜,包含以下质量百分比的组分:
鳄鱼油5%、积雪草苷3%、甘油葡糖苷2.5%、异硬脂酰乳酸钠1.5%、甘油硬脂酸酯0.7%、PEG-100硬脂酸酯0.25%、月桂醇聚醚-7 0.25%、甘油5%、1,3-丙二醇2.5%、透明质酸钠0.05%、糖基海藻糖2%、β-葡聚糖2%、甜菜碱2%、生育酚乙酸酯0.5%、月桂氮卓酮1%、酵母提取物0.25%、鲸蜡硬脂醇2%、聚二甲基硅氧烷2%、异十六烷8%、霍霍巴(SIMMONDSIA CHINENSIS)籽油2.5%、肉豆蔻酸异丙酯2.5%、辛酸/癸酸甘油三酯2.5%、C13-C14异链烷烃0.3%、卡波姆0.2%、聚丙烯酰胺0.3%、肉桂(CINNAMOMUM CASSIA)树皮提取物0.3%、八角茴香(ILLICIUMVERUM)果提取物0.3%、茵陈蒿(ARTEMISIA CAPILLARIS)提取物0.3%、三乙醇胺0.2%、视黄醇1%、人参皂甙2%、神经酰胺3 0.1%、水 余量。
制备方法:
(1)将鳄鱼油、异硬脂酰乳酸钠、甘油硬脂酸酯、PEG-100硬脂酸酯、月桂氮卓酮、鲸蜡硬脂醇、生育酚乙酸酯、聚二甲基硅氧烷、异十六烷、霍霍巴(SIMMONDSIA CHINENSIS)籽油、肉豆蔻酸异丙酯、辛酸/癸酸甘油三酯依次投入油相锅,搅拌下升温到80℃,溶解均匀,制得油相备用;
(2)将甘油、1,3-丙二醇、透明质酸钠、卡波姆预先混匀,投入乳化锅,然后投入水、糖基海藻糖、β-葡聚糖、甜菜碱、甘油葡糖苷,搅拌下升温到85℃,2000rpm均质3分钟,保温30分钟备用;
(3)将油相抽入乳化锅,开启3000rpm均质5-6分钟,然后保温搅拌20分钟;加入三乙醇胺,搅拌均匀;再加入聚丙烯酰胺、C13-C14异链烷烃、月桂醇聚醚-7,开启3000rpm均质2-3分钟,降温到45℃;
(4)加入预先用水溶解好的积雪草苷和人参皂甙,以及视黄醇、神经酰胺3、肉桂(CINNAMOMUM CASSIA)树皮提取物、八角茴香(ILLICIUM VERUM)果提取物、茵陈蒿(ARTEMISIA CAPILLARIS)提取物,搅拌均匀,3000rpm均质1-2分钟,降温到38℃即可出料。
实施例5
一种祛疤霜,包含以下质量百分比的组分:
鳄鱼油5%、积雪草苷3%、甘油葡糖苷2.5%、异硬脂酰乳酸钠1.5%、甘油硬脂酸酯0.7%、PEG-100硬脂酸酯0.25%、月桂醇聚醚-7 0.25%、甘油5%、1,3-丙二醇2.5%、透明质酸钠0.05%、糖基海藻糖2%、β-葡聚糖2%、甜菜碱2%、生育酚乙酸酯0.5%、月桂氮卓酮1%、酵母提取物0.25%、鲸蜡硬脂醇2%、聚二甲基硅氧烷2%、异十六烷8%、霍霍巴(SIMMONDSIA CHINENSIS)籽油2.5%、肉豆蔻酸异丙酯2.5%、辛酸/癸酸甘油三酯2.5%、C13-C14异链烷烃0.3%、卡波姆0.2%、聚丙烯酰胺0.3%、肉桂(CINNAMOMUM CASSIA)树皮提取物0.3%、八角茴香(ILLICIUMVERUM)果提取物0.3%、茵陈蒿(ARTEMISIA CAPILLARIS)提取物0.3%、三乙醇胺0.2%、视黄醇5%、人参皂甙0.1%、神经酰胺3 1%、水 余量。
制备方法:同实施例4。
对比例1
一种祛疤霜,包含以下质量百分比的组分:
积雪草苷3%、甘油葡糖苷2.5%、异硬脂酰乳酸钠1.5%、甘油硬脂酸酯0.7%、PEG-100硬脂酸酯0.25%、月桂醇聚醚-7 0.25%、甘油5%、1,3-丙二醇2.5%、透明质酸钠0.05%、糖基海藻糖2%、β-葡聚糖2%、甜菜碱2%、生育酚乙酸酯0.5%、月桂氮卓酮1%、酵母提取物0.25%、鲸蜡硬脂醇2%、聚二甲基硅氧烷2%、异十六烷8%、霍霍巴(SIMMONDSIA CHINENSIS)籽油2.5%、肉豆蔻酸异丙酯2.5%、辛酸/癸酸甘油三酯2.5%、C13-C14异链烷烃0.3%、卡波姆0.2%、聚丙烯酰胺0.3%、肉桂(CINNAMOMUM CASSIA)树皮提取物0.3%、八角茴香(ILLICIUM VERUM)果提取物0.3%、茵陈蒿(ARTEMISIA CAPILLARIS)提取物0.3%、三乙醇胺0.2%、水 余量。
制备方法:同实施例1。
对比例2
一种祛疤霜,包含以下质量百分比的组分:
鳄鱼油5%、甘油葡糖苷2.5%、异硬脂酰乳酸钠1.5%、甘油硬脂酸酯0.7%、PEG-100硬脂酸酯0.25%、月桂醇聚醚-7 0.25%、甘油5%、1,3-丙二醇2.5%、透明质酸钠0.05%、糖基海藻糖2%、β-葡聚糖2%、甜菜碱2%、生育酚乙酸酯0.5%、月桂氮卓酮1%、酵母提取物0.25%、鲸蜡硬脂醇2%、聚二甲基硅氧烷2%、异十六烷8%、霍霍巴(SIMMONDSIA CHINENSIS)籽油2.5%、肉豆蔻酸异丙酯2.5%、辛酸/癸酸甘油三酯2.5%、C13-C14异链烷烃0.3%、卡波姆0.2%、聚丙烯酰胺0.3%、肉桂(CINNAMOMUM CASSIA)树皮提取物0.3%、八角茴香(ILLICIUM VERUM)果提取物0.3%、茵陈蒿(ARTEMISIA CAPILLARIS)提取物0.3%、三乙醇胺0.2%、水 余量。
制备方法:同实施例1。
对比例3
一种祛疤霜,包含以下质量百分比的组分:
鳄鱼油5%、积雪草苷3%、异硬脂酰乳酸钠1.5%、甘油硬脂酸酯0.7%、PEG-100硬脂酸酯0.25%、月桂醇聚醚-7 0.25%、甘油5%、1,3-丙二醇2.5%、透明质酸钠0.05%、糖基海藻糖2%、β-葡聚糖2%、甜菜碱2%、生育酚乙酸酯0.5%、月桂氮卓酮1%、酵母提取物0.25%、鲸蜡硬脂醇2%、聚二甲基硅氧烷2%、异十六烷8%、霍霍巴(SIMMONDSIA CHINENSIS)籽油2.5%、肉豆蔻酸异丙酯2.5%、辛酸/癸酸甘油三酯2.5%、C13-C14异链烷烃0.3%、卡波姆0.2%、聚丙烯酰胺0.3%、肉桂(CINNAMOMUM CASSIA)树皮提取物0.3%、八角茴香(ILLICIUM VERUM)果提取物0.3%、茵陈蒿(ARTEMISIA CAPILLARIS)提取物0.3%、三乙醇胺0.2%、水 余量。
制备方法:同实施例1。
对比例4
一种祛疤霜,包含以下质量百分比的组分:
鳄鱼油5%、积雪草苷3%、甘油葡糖苷2.5%、异硬脂酰乳酸钠1.5%、甘油硬脂酸酯0.7%、PEG-100硬脂酸酯0.25%、月桂醇聚醚-7 0.25%、甘油5%、1,3-丙二醇2.5%、透明质酸钠0.05%、糖基海藻糖2%、β-葡聚糖2%、甜菜碱2%、生育酚乙酸酯0.5%、月桂氮卓酮1%、酵母提取物0.25%、鲸蜡硬脂醇2%、聚二甲基硅氧烷2%、异十六烷8%、霍霍巴(SIMMONDSIA CHINENSIS)籽油2.5%、肉豆蔻酸异丙酯2.5%、辛酸/癸酸甘油三酯2.5%、C13-C14异链烷烃0.3%、卡波姆0.2%、聚丙烯酰胺0.3%、肉桂(CINNAMOMUM CASSIA)树皮提取物0.3%、八角茴香(ILLICIUMVERUM)果提取物0.3%、茵陈蒿(ARTEMISIA CAPILLARIS)提取物0.3%、三乙醇胺0.2%、视黄醇5%、神经酰胺3 1%、水 余量。
制备方法:同实施例4。
对比例5
一种祛疤霜,包含以下质量百分比的组分:
鳄鱼油5%、积雪草苷3%、甘油葡糖苷2.5%、异硬脂酰乳酸钠1.5%、甘油硬脂酸酯0.7%、PEG-100硬脂酸酯0.25%、月桂醇聚醚-7 0.25%、甘油5%、1,3-丙二醇2.5%、透明质酸钠0.05%、糖基海藻糖2%、β-葡聚糖2%、甜菜碱2%、生育酚乙酸酯0.5%、月桂氮卓酮1%、酵母提取物0.25%、鲸蜡硬脂醇2%、聚二甲基硅氧烷2%、异十六烷8%、霍霍巴(SIMMONDSIA CHINENSIS)籽油2.5%、肉豆蔻酸异丙酯2.5%、辛酸/癸酸甘油三酯2.5%、C13-C14异链烷烃0.3%、卡波姆0.2%、聚丙烯酰胺0.3%、肉桂(CINNAMOMUM CASSIA)树皮提取物0.3%、八角茴香(ILLICIUMVERUM)果提取物0.3%、茵陈蒿(ARTEMISIA CAPILLARIS)提取物0.3%、三乙醇胺0.2%、人参皂甙0.1%、神经酰胺3 1%、水 余量。
制备方法:同实施例4。
实施例6
对实施例1-5和对比例1-6的祛疤霜进行功效评价(对比例6为一款市售祛疤霜)。具体测试方法如下:各实验组均选取10名志愿者,年龄20-50岁,均存在疤痕;使用方法:取适量祛疤霜涂抹在有疤痕的皮肤上,轻轻按摩3-5分钟,1晚1次,连续试用12周,拍照存档。评价方法:对比第0天和第12周照片,其中疤痕显著淡化的为显效;疤痕有一定淡化的为有效;疤痕皮肤没有改善的为无效。试用12周后对试用者进行回访,均没有出现皮肤过敏的现象,表明该护发乳安全无毒。具体测试结果如表1。
表1 测试结果记录表
显效 | 有效 | 无效 | |
实施例1 | 6 | 1 | 3 |
实施例2 | 6 | 3 | 1 |
实施例3 | 5 | 3 | 2 |
实施例4 | 8 | 2 | 0 |
实施例5 | 8 | 1 | 1 |
对比例1 | 1 | 1 | 8 |
对比例2 | 0 | 2 | 8 |
对比例3 | 1 | 2 | 7 |
对比例4 | 5 | 3 | 2 |
对比例5 | 5 | 2 | 3 |
对比例6 | 1 | 2 | 7 |
由表1的结果可见:
实施例1-5与对比例1-6对比可见,本发明实施例所制得的祛疤霜的效果明显好于对比例;
实施例4-5与实施例1-3对比可见,视黄醇、人参皂甙、神经酰胺3的加入对于祛疤效果有明显的促进作用;
实施例3与对比例1-3对比可见,鳄鱼油、积雪草苷、甘油葡糖苷三个原料合用时效果更佳,体现了协同增效的作用。
实施例5与对比例4-5对比可见,视黄醇、人参皂甙、神经酰胺3三个原料合用时效果更佳。
以上所述实施例仅表达了本发明的几种实施方式,其描述较为具体和详细,但并不能因此而理解为对发明专利范围的限制。应当指出的是,对于本领域的普通技术人员来说,在不脱离本发明构思的前提下,还可以做出若干变形和改进,这些都属于本发明保护范围。因此,本发明专利的保护范围应以所附权利要求为准。
Claims (9)
1.一种祛疤组合物,其特征在于,所述祛疤组合物包括以下质量百分比的组分:鳄鱼油1-10%、积雪草苷0.5-5%、甘油葡糖苷0.5-5%。
2.根据权利要求1所述的祛疤组合物,其特征在于,所述祛疤组合物还包括以下质量百分比的组分:视黄醇1-5%、人参皂甙0.1-2%、神经酰胺3 0.1-1%。
3.根据权利要求1或2所述的祛疤组合物,其特征在于,所述祛疤组合物还包括以下质量百分比的组分:乳化剂1.65-4%、保湿剂3.51-24.1%、皮肤调理剂0.3-3.5%、润肤剂10.1-34.5%、增稠剂0.2-0.8%、防腐剂0.3-1.5%。
4.根据权利要求3所述的祛疤组合物,其特征在于,所述乳化剂包括以下组分:异硬脂酰乳酸钠1-2%、甘油硬脂酸酯0.5-1%、PEG-100硬脂酸酯0.1-0.5%、月桂醇聚醚-7 0.05-0.5%。
5.根据权利要求3所述的祛疤组合物,其特征在于,所述保湿剂包括以下组分:甘油1-10%、1,3-丙二醇1-5%、透明质酸钠0.01-0.1%、糖基海藻糖0.5-3%、甜菜碱0.5-3%。
6.根据权利要求3所述的祛疤组合物,其特征在于,所述皮肤调理剂包括以下组分:生育酚乙酸酯0.1-1%、月桂氮卓酮0.1-2%、β-葡聚糖0.5-3%、酵母提取物0.1-0.5%。
7.根据权利要求3所述的祛疤组合物,其特征在于,所述润肤剂包括以下组分:鲸蜡硬脂醇1-4%、聚二甲基硅氧烷1-5%、异十六烷5-10%、霍霍巴(SIMMONDSIA CHINENSIS)籽油1-5%、肉豆蔻酸异丙酯1-5%、辛酸/癸酸甘油三酯1-5%、C13-C14异链烷烃0.1-0.5%。
8.根据权利要求3所述的祛疤组合物,其特征在于,所述增稠剂包括以下组分:卡波姆0.1-0.3%、聚丙烯酰胺0.1-0.5%。
9.根据权利要求3所述的祛疤组合物,其特征在于,所述防腐剂包括以下组分:肉桂(CINNAMOMUM CASSIA)树皮提取物0.1-0.5%、八角茴香(ILLICIUM VERUM)果提取物0.1-0.5%、茵陈蒿(ARTEMISIA CAPILLARIS)提取物0.1-0.5%。
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CN112691073A (zh) * | 2021-01-26 | 2021-04-23 | 广州华厦生物制药有限公司 | 一种植物益生菌负离子靓牙慕斯及其制备方法 |
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