CN107960663A - Carbonic acid calcium-nutrition intensifying agent and preparation method - Google Patents
Carbonic acid calcium-nutrition intensifying agent and preparation method Download PDFInfo
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- CN107960663A CN107960663A CN201711204136.4A CN201711204136A CN107960663A CN 107960663 A CN107960663 A CN 107960663A CN 201711204136 A CN201711204136 A CN 201711204136A CN 107960663 A CN107960663 A CN 107960663A
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- Prior art keywords
- carbonic acid
- acid calcium
- intensifying agent
- nutrition intensifying
- calcium
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- 239000003795 chemical substances by application Substances 0.000 title claims abstract description 99
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 title claims abstract description 89
- 238000002360 preparation method Methods 0.000 title claims abstract description 31
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 167
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract description 83
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims abstract description 43
- 239000008101 lactose Substances 0.000 claims abstract description 43
- 229960001375 lactose Drugs 0.000 claims abstract description 42
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims abstract description 41
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 37
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 34
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 34
- 239000011812 mixed powder Substances 0.000 claims abstract description 32
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 26
- 239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 26
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 26
- 229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 26
- 229960003563 calcium carbonate Drugs 0.000 claims abstract description 13
- 239000002994 raw material Substances 0.000 claims abstract description 13
- 238000002156 mixing Methods 0.000 claims description 33
- 239000000203 mixture Substances 0.000 claims description 32
- 239000000843 powder Substances 0.000 claims description 14
- 238000009472 formulation Methods 0.000 claims description 11
- 238000000034 method Methods 0.000 abstract description 24
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract description 12
- 239000011575 calcium Substances 0.000 abstract description 12
- 229910052791 calcium Inorganic materials 0.000 abstract description 12
- 230000000295 complement effect Effects 0.000 abstract description 4
- 239000007788 liquid Substances 0.000 abstract description 3
- 239000000725 suspension Substances 0.000 abstract description 2
- 238000013461 design Methods 0.000 description 11
- 238000005259 measurement Methods 0.000 description 10
- 238000004364 calculation method Methods 0.000 description 8
- 238000010521 absorption reaction Methods 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 238000010348 incorporation Methods 0.000 description 5
- 239000000654 additive Substances 0.000 description 4
- 230000000996 additive effect Effects 0.000 description 4
- 238000003556 assay Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 229920001353 Dextrin Polymers 0.000 description 3
- 239000004375 Dextrin Substances 0.000 description 3
- 235000019738 Limestone Nutrition 0.000 description 3
- 235000019425 dextrin Nutrition 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000006028 limestone Substances 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 229910021532 Calcite Inorganic materials 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 description 2
- RAHZWNYVWXNFOC-UHFFFAOYSA-N Sulphur dioxide Chemical compound O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 description 2
- 241000209140 Triticum Species 0.000 description 2
- 235000021307 Triticum Nutrition 0.000 description 2
- 230000001133 acceleration Effects 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 235000010980 cellulose Nutrition 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 239000004579 marble Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 210000000697 sensory organ Anatomy 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 235000015961 tonic Nutrition 0.000 description 2
- 230000001256 tonic effect Effects 0.000 description 2
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 241000235342 Saccharomycetes Species 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 241000607768 Shigella Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 239000005862 Whey Substances 0.000 description 1
- 102000007544 Whey Proteins Human genes 0.000 description 1
- 108010046377 Whey Proteins Proteins 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000005030 aluminium foil Substances 0.000 description 1
- 229910052785 arsenic Inorganic materials 0.000 description 1
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 125000005586 carbonic acid group Chemical group 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 229940099112 cornstarch Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 235000013312 flour Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229960000716 tonics Drugs 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 235000008939 whole milk Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
- A23L29/35—Degradation products of starch, e.g. hydrolysates, dextrins; Enzymatically modified starches
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/40—Shaping or working of foodstuffs characterised by the products free-flowing powder or instant powder, i.e. powder which is reconstituted rapidly when liquid is added
- A23P10/43—Shaping or working of foodstuffs characterised by the products free-flowing powder or instant powder, i.e. powder which is reconstituted rapidly when liquid is added using anti-caking agents or agents improving flowability, added during or after formation of the powder
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
This application discloses a kind of preparation method of carbonic acid calcium-nutrition intensifying agent, this method includes：Weigh at least one of calcium carbonate and lactose, microcrystalline cellulose and maltodextrin of preset quality percentage；The premixing of at least one of the calcium carbonate weighed and lactose, microcrystalline cellulose or maltodextrin is obtained into premix；Premix is smashed to obtain mixed-powder；Mixed-powder is uniformly mixed by mixer.Through the above way, it is good and be not easy the carbonic acid calcium-nutrition intensifying agent united that a kind of Combination can be prepared, can solve calcium carbonate when as calcium complement agent because poor fluidity, be not easy to mix, easily unite the problems such as, caused by reconstitute or liquid form product in there are the technical problems such as suspension difference.The application also provides a kind of carbonic acid calcium-nutrition intensifying agent, and the raw material of carbonic acid calcium-nutrition intensifying agent includes calcium carbonate and at least one of lactose and maltodextrin；The carbonic acid calcium-nutrition intensifying agent is preparation method preparation gained from the above mentioned.
Description
Technical field
This application involves additive preparing technical field, more particularly to carbonic acid calcium-nutrition intensifying agent and preparation method.
Background technology
Calcium carbonate, is commonly called as：Lime stone, lime stone, mountain flour, marble etc..Main component：Calcite, English is entitled
Calcium carbonate, chemical formula are CaCO3, relative molecular weight 100.09.It is Common materials on the earth to calcium carbonate,
It is present in the rocks such as aragonite, calcite, chalk, limestone, marble, calcareous tufa, is also the main of animal skeleton or shell
Component, can use as additive in food industry and can make calcium tonic：Absorptivity is up to 39%.Carbonic acid calcium absorptivity is reachable
39%, it has also become formulation at most, using most calcium tonics.But calcium carbonate is in neutrality, it is substantially insoluble in, is dissolved in salt
Acid.Poor fluidity of calcium carbonate when as calcium complement agent in the product, is not easy to mix, reconstitute or liquid form product in hang
Buoyancy difference influences product quality, these characteristics determine that calcium carbonate applications are very restricted.
The content of the invention
The application mainly solving the technical problems that, there is provided one kind can solve calcium carbonate and is not easy when as calcium complement agent
It is uniformly mixed and the preparation method for the carbonic acid calcium-nutrition intensifying agent of technical problem of easily uniting etc..
In order to solve the above technical problems, the technical solution that the application uses is：A kind of carbonic acid calcium-nutrition intensifying agent is provided
Preparation method, comprises the following steps：
Weigh at least one of calcium carbonate and lactose, microcrystalline cellulose and maltodextrin of preset quality percentage；
At least one of the calcium carbonate and lactose, microcrystalline cellulose or maltodextrin for being weighed are pre-mixed
To premix；
The premix is smashed to obtain mixed-powder；
The mixed-powder is uniformly mixed by mixer.
In order to solve the above technical problems, another technical solution that the application uses is：It is strong to provide a kind of calcium carbonate nutrition
Agent, the raw material of the carbonic acid calcium-nutrition intensifying agent include calcium carbonate and lactose, microcrystalline cellulose and maltodextrin extremely
Few one kind；The carbonic acid calcium-nutrition intensifying agent is to prepare gained by preparation method as described above.
The beneficial effect of above technical scheme is：The situation of the prior art is different from, the application passes through according to preset quality
At least one of the calcium carbonate and lactose of percentage, microcrystalline cellulose and maltodextrin, and by the calcium carbonate weighed with
And lactose, microcrystalline cellulose or maltodextrin are pre-mixed to obtain premix, premix is smashed to obtain mixed-powder, will be mixed
Powder is uniformly mixed by mixer, good and be not easy the carbonic acid calcium-nutrition intensifying agent united to obtain Combination, preferable to solve
Calcium carbonate when as calcium complement agent because of poor fluidity, be not easy to mix, the characteristic such as easily unite, caused by reconstituting or liquid production
Occur the technical problems such as suspension difference in product.
Brief description of the drawings
Fig. 1 is a kind of flow diagram of one embodiment of preparation method of carbonic acid calcium-nutrition intensifying agent of the application；
Fig. 2 is a kind of flow diagram of another embodiment of preparation method of carbonic acid calcium-nutrition intensifying agent of the application；
Fig. 3 is a kind of flow diagram of the another embodiment of preparation method of carbonic acid calcium-nutrition intensifying agent of the application.
Embodiment
Hereinafter, it will be described with reference to the accompanying drawings the exemplary embodiment of the application.For clear and brief purpose, no
Function known to detailed description and construction.The term described below being limited in view of the function in the application can according to
The intention or implementation of family and operator and difference.Therefore, it should the art is limited on the basis of disclosed in entire disclosure
Language.
Referring to Fig. 1, the flow diagram of the embodiment for the preparation method of the application carbonic acid calcium-nutrition intensifying agent.Should
Method includes：
S10：Weigh at least one in the calcium carbonate and microcrystalline cellulose of preset quality percentage, lactose and maltodextrin
Kind.
Calcium carbonate is necessary raw material in step S10, in different embodiments another raw material be microcrystalline cellulose, lactose
At least one of with maltodextrin, either any two kinds therein or three kinds, this is not specifically limited.
Alternatively, preset quality percentage is specifically true according to the percentage of the required carbonic acid calcium-nutrition intensifying agent produced
It is fixed, i.e., when it is required it is to be prepared be calcium carbonate content higher carbonic acid calcium-nutrition intensifying agent when, the preset quality hundred that is weighed
Divide the ratio of calcium carbonate in the calcium carbonate and lactose and maltodextrin of ratio will be correspondingly improved.
Alternatively, the preset quality percentage of at least one of calcium carbonate and lactose, microcrystalline cellulose and maltodextrin
Ratio be specially：1-95：5-99.
In one embodiment, when what is weighed is calcium carbonate and lactose, when the mass percent of the calcium carbonate weighed
For 1% when, then the mass percent of the lactose weighed is 99%.When the mass percent of the calcium carbonate weighed is 2%
When, then the required mass percent weighed is 98%.It is appreciated that the mass percent for working as weighed calcium carbonate is n%
When (n% is more than 0 for one, and one less than 1 value, does not limit specifically), then the mass percent of the required lactose weighed
For (1-n%).
In another embodiment, when weighed be in calcium carbonate and lactose, microcrystalline cellulose or maltodextrin at least
During two kinds of mixture, when the mass percent of the calcium carbonate weighed is n%, (n% is for one more than 0, one less than 1
Value, does not limit specifically), then at least two mixture in the required lactose weighed, microcrystalline cellulose or maltodextrin
Mass percent be (1-n%).
Alternatively, lactose (lactose molecule formula C12H22O11) is that one kind crystallizes and through works such as drying, grindings from whey
Edible carbohydrate made of skill.Maltodextrin (molecular formula (C6H10O5) n) be one kind using starch or starchiness as raw material, through enzyme process
Small-molecule substance made of minuent hydrolysis, refined, spray drying.
Alternatively, in one embodiment, the lactose weighed is that moisture is less than or equal to 6.0%, and ash content is less than or equal to
0.3%, PH (10% aqueous solution) value is between 4.5-7, and mesh number is in 95 (the sieve percent of pass for selecting 100 mesh is 95%) mesh
Lactose above.The microorganism of wherein selected lactose will meet following index：Every gram of total plate count is less than 1000, mould and
Every gram of saccharomycete is less than 25, and every gram of coliform is less than 10, and the specific targets of the microorganism of other classifications are according to national mark
Accurate and actual product needs to be set.It is understood that can be for each of the lactose weighed before lactose is weighed
A component target is sampled and measures, to judge whether lactose meets the requirement of production.
Alternatively, in one embodiment, the maltodextrin weighed is to judge amorphous powder through naked eyes, is visible by naked eyes
Impurity, DE value 16-20, moisture are less than or equal to 6%, and solubility is more than or equal to 98%, and pH value (10% aqueous solution) is in 4.5-6.5
Between, the content of sulfated ash is less than or equal to 0.6%, mesh number 95% (the sieve percent of pass for selecting 100 mesh is 95%) with
On.It is required to be less than or equal to 0.5mg/kg for the measure of pollutant lead (Pb) and arsenic (As), copper (Cu) is less than or equal to 5.0mg/
Kg, sulfur dioxide 0.03g/kg.Measure for microorganism is that every gram of total plate count is less than or equal to 1000, and yeast and mold is every
Gram it is less than or equal to 25, every gram of coliform is less than or equal to 10, pathogenic bacteria (salmonella, Shigella, staphylococcus aureus)
When mushroom is determined as 0, then judge selected maltodextrin for qualified raw material.
S20：At least one of the calcium carbonate weighed and lactose, microcrystalline cellulose or maltodextrin kind is pre-mixed
To premix.
Alternatively, by the calcium carbonate and lactose that are weighed in step S10, microcrystalline cellulose or maltodextrin kind at least
A kind of pre- be added in mixer mixes the default time to obtain premix.Premix is by the calcium carbonate weighed and breast
Sugar, microcrystalline cellulose or maltodextrin step S10 weigh the calcium carbonate and lactose, microcrystalline cellulose of the preset quality percentage of gained
The mixture of element or at least one gained after preliminary mixing of maltodextrin kind.It is understood that it will be weighed
At least one of calcium carbonate and lactose, microcrystalline cellulose or maltodextrin kind can add to be mixed into mixer,
Can also add to realize in the equipment of mixed function and mixed to other, specifically, the equipment for realizing mixing
It is not particularly limited herein.
Alternatively, in one embodiment, by the calcium carbonate weighed and lactose, microcrystalline cellulose or maltodextrin kind
At least one is added in mixer mixes preset time with default mixing rate.
Alternatively, it is 60-80r/min to preset mixing rate；Preset time 5-10min.It is understood that default
Mixing rate can be 60-80r/min in any one value, preset time can be 5-10min in any one
Value.Specifically, when default mixing rate value is bigger, corresponding default incorporation time then can be reduced mutually, but specifically
Or default incorporation time and default mixing rate are subject to, does not do limit one by one herein.
In one embodiment, mixing rate 60r/min, preset time 10min, the calcium carbonate that will be weighed and
At least one be added in mixer of lactose, microcrystalline cellulose or maltodextrin kind is mixed with the mixing rate of 60r/min
The 10min times.
In another embodiment, mixing rate 75r/min, preset time 8min.
In another embodiment, the speed of mixing is 80r/min, preset time 5min.
S30：Premix is smashed to obtain mixed-powder.
Alternatively, step S30 is further to be smashed mixing gained premix in step S20 to obtain mixed powder
End.Mixed-powder refers to the mixture that gained is powdered after gained premix in step S20 is smashed.It is appreciated that
It is that step S20 can add the premix to that further smashed or added in disintegrating machine can be with to other
Realize in the equipment smashed and carry out realization smashing, for realizing that the equipment smashed is not particularly limited herein.
Alternatively, in one embodiment, step S30 be will premix add disintegrating machine in crush using obtain smash mesh number as
The mixed-powder of 80-3500 mesh.It is understood that can set in disintegrating machine smashes mesh number as 80-3500 mesh scopes
In any one integer value, it is specific smash mesh number and do not do herein limits one by one.
In one embodiment, gained premix in step S20 is added to disintegrating machine respectively with 100 mesh, 800 mesh, 1200
Purpose smashes mesh number and is smashed, to obtain 100 mesh, 800 mesh, 1200 mesh powders.
Alternatively, when required smashing mesh number is different, selected disintegrating machine also has difference.
In one embodiment, when required smashing mesh number is 100 mesh, then common disintegrating machine is selected.
In another embodiment, when required smashing mesh number is 1200 mesh, then ultra micro disintegrating machine can be selected.
Alternatively, after step S30, the detection for gained mixed-powder is further included, is detection gained mixed-powder
Whether the standard of default smashing mesh number is met.S40：Mixed-powder is uniformly mixed by mixer.
Alternatively, mixed-powder is uniformly mixed by mixer.Wherein mixed-powder can be that gained is mixed in step S30
Close powder or by the calcium carbonate of gained preset quality percentage and lactose, microcrystalline cellulose or wheat the step of other
The mixed-powder of at least one gained after step S20 and step S30 of bud dextrin kind is added into mixer into traveling one
The mixing of step.
Alternatively, in one embodiment, step S40 further comprises：Mixed-powder is added in mixer with 60-
The mixing rate mixing 8-15min of 80r/min.It is understood that the mixing rate of mixer can be 60-80r/min
Any one integer value, incorporation time can be any one value in 8-15min, do not do specifically and limit one by one herein.
Alternatively, in one embodiment, further include after the step s 40：To after mixing gained mixed-powder into
Row is once or multitime feedback.It is understood that for gained mixed-powder carry out feed back number of processing according to for
The judgement of the abundant degree of mixing of mixed-powder determines, when the powder for having more amount occurs mixing non-uniform, Ke Yishe
It is fixed to carry out more multiple feed back processing.When the judgement that abundant degree is mixed to mixed-powder is preferable, that is, there is less mixing not
When uniform situation either mixes preferable situation, process that is less or not setting feed back processing can be set, specifically
Do not limit herein.
Alternatively, 7min is more than to one or many feed back times that gained mixed-powder carries out after mixing.Can be with
Understand be when repeatedly carry out feed back when, the time of feed back can be set as less time such as 7min as needed, when return
When the number of material is less, the time that can set feed back is relatively more such as 15min.
Alternatively, in one embodiment, further included after step S40：Exist to the carbonic acid calcium-nutrition intensifying agent product of gained
The medicinal clean area of national Specification is packed.For example, seal-packed specification is 5kg-50kg/ bags.Specifically
, seal-packed specification does specific adjustment according to actual conditions, this is not limited.
Alternatively, prepared carbonic acid calcium-nutrition intensifying agent is that (formulation refers to for the formulation of any one value in 1%-98%
It is the different carbonic acid calcium-nutrition intensifying agent of calcium carbonate content).It is understood that carbonic acid calcium-nutrition intensifying agent described in this programme
Preparation method prepared by the carbonic acid calcium-nutrition intensifying agent for any one value in 1%-98%.
Further explanation is done below by way of specific example：
Refering to Fig. 2, in one embodiment, there is provided a kind of preparation method of 25% carbonic acid calcium-nutrition intensifying agent, including it is following
Step：
S11：Weigh 26kg calcium carbonate and 74kg maltodextrins.
Alternatively, wherein the calcium carbonate quality weighed needs to consider the loss in production process, so weighing carbonic acid
± the 1% of the target content that the calcium carbonate mass percent weighed can be controlled accordingly during calcium, to consider to produce
Waste in journey.
S12：By the maltodextrin weighed and calcium carbonate, premix 10min obtains premix in cone-type mixer.
S13：Premix is crushed with pulverizer to smash mesh number as 100 mesh, obtains mixed-powder.
S14：By mixed-powder using mixing rate as 60-80r/min in cone-type mixer, incorporation time 8-
15min, feed back time are 7-8min.
25% carbonic acid calcium-nutrition intensifying agent can be prepared by step S11 to step S14, after the completion of preparation, to institute
Product is obtained to be sealed according to default specification.Strengthen in order to which 25% calcium carbonate applications obtained by above method are better described
Agent has the advantages that stability height, uniformly mixed etc. are related, below to 25% calcium carbonate applications prepared in the above method
Each technical indicator of hardening agent is measured, and specific measure situation includes as follows：
1st, sense organ measures
25% carbonic acid calcium-nutrition intensifying agent product is accelerated 6 months in 37 DEG C of climatic chambers, observes by the naked eye hair
Existing 25% carbonic acid calcium-nutrition intensifying agent product white powder of appearance after accelerating 1 month, 3 months and 6 months, no caking,
So can be determined that it is good by 25% carbonic acid calcium-nutrition intensifying agent product color stable homogeneous prepared by the above method.
2nd, mixture homogeneity measures
10g25% carbonic acid calcium-nutrition intensifying agent products are separately added into 1kg whole milk powders and 1kg maltodextrins, referring to
Trace element premixing feed mixture homogeneity assay method measures its mixture homogeneity, and measurement result is as shown in table 1, by table 1
Understand, the product mix uniformity is 2.75%, it is seen that its Combination is good.
Table 11：The mixture homogeneity of 25% formulation carbonic acid calcium-nutrition intensifying agent product of 100 ratios is surveyed
Determine result (in terms of calcium)
3rd, Stability Determination
25% carbonic acid calcium-nutrition intensifying agent product is accelerated 6 months in 37 DEG C of climatic chambers, detects carbonic acid in product
The content of calcium, and the attenuation rate of product is calculated, the calculation formula of attenuation rate is：Attenuation rate=(contain original amount-acceleration moon
Amount)/original amount, measurement result is as shown in table 2.As shown in Table 2, as 25% carbonic acid calcium-nutrition intensifying prepared by the above method
Agent product its attenuation rate after accelerating 1 month is 2.6%, its attenuation rate is 3.6% after accelerating 3 months, it declines after accelerating 6 months
Lapse rate is 4.46%, and the measurement result of the above may determine that the 25% carbonic acid calcium-nutrition intensifying agent production prepared by the above method
The high stability of product.
Influence of 2 acceleration time of table to 1% carbonic acid calcium-nutrition intensifying agent product calcium carbonate content
4th, angle of repose, bulk density measure
Angle of repose, the assay method of bulk density are with reference to powder overall characteristic analyzer method, after measured, 25% in the present embodiment
Carbonic acid calcium-nutrition intensifying agent product angle of repose is 48.0 °, can preferably meet the need for liquidity in production process, bulk density
For 0.535g/mL, tight ness rating 0.8443g/mL, disclosure satisfy that different product demand.
5th, yield calculates
Product yield (the index of the amount of actually generating of description product, equal to the amount of actually generating/reason of product in the present embodiment
By growing amount (total amount of dispensing)) calculation formula be：Yield=product quality/dispensing gross weight=97.03/100*100%=
97%, so can be determined that out that the yield for the product prepared in the above method is higher from the calculating of upper number.
6th, calcium carbonate actual content accounts for design percentage composition and calculates
In the present embodiment calcium carbonate actual content account for design percentage composition calculation formula be：
Calcium carbonate actual content accounts for design percentage composition=calcium carbonate actual content/design content * 100%=
25.35%/25.48=99.48%,
Wherein, the calculation formula for designing content is：
Calcium carbonate additive amount/dispensing gross weight * 100%=26*98%/100*100%=25.48%.
7th, hydroscopicity calculates
By 25% carbonic acid calcium-nutrition intensifying agent product under conditions of relative humidity is 60%, when placement 48 is small, weigh, put down
Row measure twice, is averaged, and calculates hydroscopicity according to the following formula：Hydroscopicity=(heavy before gross weight-moisture absorption after moisture absorption
Amount-glassware weight) weight * 100% before/moisture absorption, measurement result is as shown in table 3, and as shown in Table 3, product hydroscopicity is
0.6%.
The hydroscopicity measurement result of 3 1% carbonic acid calcium-nutrition intensifying agent product of table
In conclusion product manufactured in the present embodiment is white powder, product quality 97.03kg, yield is
97.00%, hydroscopicity 0.6%, calcium carbonate actual content is 25.35%, reaches the 99.48% of design content.Therefore, this Shen
Carbonic acid calcium-nutrition intensifying agent that please be prepared by above method, which has, to be uniformly mixed, and is not easy to unite, the features such as stability is high.
Refering to Fig. 3, in another embodiment, there is provided a kind of preparation method of 50% carbonic acid calcium-nutrition intensifying agent, including with
Lower step：
S21：Weigh 52kg calcium carbonate and 48kg lactose or maltodextrin.
S22：By the lactose weighed or maltodextrin and calcium carbonate, premix 10min obtains premix in cone-type mixer.
S23：Premix 1200 mesh of micronizer is crushed, mixed-powder is obtained and (crushing of micronizer is set
Pressure is 0.8-0.9MPa, and raw material push-in pressure is 0.8-0.9MPa, treating capacity 35-45kg/Hr).
S24：By mixed-powder in cone-type mixer using mixing rate as 60-80r/min, incorporation time 8-15min,
The feed back time is 7-8min.
50% carbonic acid calcium-nutrition intensifying agent can be prepared by step S21 to step S24, is sought up to 50% calcium carbonate
Support hardening agent product.After the preparation of 50% carbonic acid calcium-nutrition intensifying agent is completed, carried out using aluminium foil bag according to default specification
Pack.There is stability height, mixing in order to which 25% calcium carbonate applications hardening agent obtained by above method is better described
The advantages of uniform etc. related, below to each technical indicator of 50% calcium carbonate applications hardening agent prepared in the above method
It is measured, specific measure situation includes as follows：
1st, sense organ measures
50% carbonic acid calcium-nutrition intensifying agent product is accelerated 6 months in 37 DEG C of climatic chambers, make discovery from observation on
It is white to state the appearance after accelerating 1 month, 3 months and 6 months of 50% carbonic acid calcium-nutrition intensifying agent product prepared by method
Powder, no caking, it is possible to judge that product color prepared by the above method is homogeneous and stability is good.
2nd, mixture homogeneity measures
5g50% carbonic acid calcium-nutrition intensifying agent products are separately added into 1kg cornstarch and 1kg maltodextrins, referring to micro-
Secondary element premixed feed mixture homogeneity assay method measures its mixture homogeneity, and measurement result is as shown in table 4, can by table 4
Know, the product mix uniformity is 1.33%, it is seen that its Combination is good.
The mixture homogeneity measurement result of 4 50% carbonic acid calcium-nutrition intensifying agent product of table, (in terms of calcium content)
3rd, Stability Determination
After 50% carbonic acid calcium-nutrition intensifying agent product is accelerated 6 months in 37 DEG C of climatic chambers, carbon in product is detected
The content of sour calcium, and calculate the attenuation rate of product.The calculation formula of attenuation rate is：Attenuation rate=(original amount-acceleration moon
Content)/original amount, specific measurement result is shown in Table 5.As shown in Table 5, product its attenuation rate after accelerating 1 month is 0.5%,
Its attenuation rate is 0.7% after accelerating 3 months, its attenuation rate is 0.7% after accelerating 6 months, can be sentenced from above-mentioned testing result
The 50% carbonic acid calcium-nutrition intensifying agent product stability determined prepared by the above method is high.
Influence of 5 acceleration time of table to 50% carbonic acid calcium-nutrition intensifying agent product calcium carbonate content
4th, angle of repose, bulk density, tight ness rating measure
Angle of repose, bulk density, the assay method of tight ness rating are with reference to powder overall characteristic analyzer method in the present embodiment, through surveying
Fixed, 5% carbonic acid calcium-nutrition intensifying agent product angle of repose is 37.5 °, can preferably meet the need for liquidity in production process,
Bulk density is 0.57g/mL, and tight ness rating 0.78g/mL, disclosure satisfy that the demand of different product.
5th, yield calculates
The calculation formula of product yield is in the present embodiment：Yield=product quality/dispensing gross weight=95.48/100*
100%=95.48%.It can be determined that in from the above result that, 50% carbonic acid calcium-nutrition intensifying agent prepared by the above method
The product yield of product is higher.
6th, calcium carbonate actual content accounts for design percentage composition and calculates
In the present embodiment calcium carbonate actual content account for design percentage composition calculation formula be：
Calcium carbonate actual content accounts for design percentage composition=calcium carbonate actual content/design content * 100%=
50.45%/50.96%*100%=98.99%,
Wherein, the calculation formula of initial designs calcium carbonate content is：
Calcium carbonate additive amount/dispensing gross weight * 100%=50.96/100*100%=50.96%.
7th, hydroscopicity calculates
By 50% carbonic acid calcium-nutrition intensifying agent product under conditions of relative humidity is 60%, when placement 48 is small, weigh, put down
Row measure twice, is averaged, and calculates hydroscopicity according to the following formula：Hydroscopicity=(heavy before gross weight-moisture absorption after moisture absorption
Amount-glassware weight) weight * 100% before/moisture absorption, measurement result is as shown in table 6, and as shown in Table 6, product hydroscopicity is
0.55%.
The hydroscopicity measurement result of 6 50% carbonic acid calcium-nutrition intensifying agent product of table
To sum up, product manufactured in the present embodiment is white powder, and product quality 95.48kg, yield 95.48%, inhales
Wet rate is 0.55%, and calcium carbonate actual content is 50.98%, reaches the 98.99% of design content.Therefore, the application is with top
Carbonic acid calcium-nutrition intensifying agent prepared by method, which has, to be uniformly mixed, and is not easy to unite, the features such as stability is high, and the product of this method
Yield is higher, can preferably reduce the loss of raw material.
Likewise, in other examples, by the preparation side of the carbonic acid calcium-nutrition intensifying agent provided in the application
The product of the carbonic acid calcium-nutrition intensifying agent of each formulation prepared by method, by the above-mentioned side for each technical indicator measure
After method is measured prepared product, it can show that the carbonic acid calcium-nutrition intensifying agent product prepared by the above method has
The features such as having and stablize, being uniformly mixed, and the preparation method of calcium carbonate provided herein is easy to operate and can be preferable
Solve calcium carbonate easily to unite, be not easy the technical problem such as uniformly mixed, the calcium carbonate battalion that stability is high, degree of mixing is high can be prepared
Support hardening agent.
The application also provides a kind of carbonic acid calcium-nutrition intensifying agent.
Alternatively, the raw material of carbonic acid calcium-nutrition intensifying agent includes calcium carbonate and lactose, microcrystalline cellulose and malt magma
At least one of essence.Specifically, the preparation method of carbonic acid calcium-nutrition intensifying agent is carbonic acid calcium-nutrition intensifying agent as described above
Preparation method, specific details are not described herein.
In one embodiment, the raw material of carbonic acid calcium-nutrition intensifying agent includes calcium carbonate and lactose, microcomputer cellulose and malt
At least one of dextrin end.It is understood that calcium carbonate is necessary preparing raw material, and lactose, microcomputer cellulose and wheat
It is at least a kind of in bud dextrin to be used as raw material, can be that can be two kinds can also be three kinds to one kind.Wherein, specific calcium carbonate
Shared mass percent is depending on the needs of product.
The mixture of two kinds or three kinds of preset percentage in dimension element and maltodextrin, specific mass percent is herein
Do not limit.
Alternatively, carbonic acid calcium-nutrition intensifying agent is powdered to crush mesh number as any value in 80-3500 mesh.Can be with
Understand, the crushing mesh number of carbonic acid calcium-nutrition intensifying agent can be any one integer value between 80-3500.Such as：
In one embodiment, the smashing mesh number of carbonic acid calcium-nutrition intensifying agent is 100 mesh.In another embodiment, carbonic acid calcium-nutrition intensifying agent
Smashing mesh number be 500.In another embodiment, the smashing mesh number of carbonic acid calcium-nutrition intensifying agent is 2500.Specifically, for carbon
The mesh number of sour calcium-nutrition intensifying agent does not limit herein.
Alternatively, carbonic acid calcium-nutrition intensifying agent includes the formulation of any one content in 1%-50%.It is appreciated that
It is that the content of the calcium carbonate in carbonic acid calcium-nutrition intensifying agent is any one value in 1%-50%, and specific content needs basis
Product needs to carry out setting adjustment.
In one embodiment, carbonic acid calcium-nutrition intensifying agent is 1% formulation, i.e., the content of calcium carbonate is in the product
15%.
In another embodiment, carbonic acid calcium-nutrition intensifying agent is 25% formulation, the i.e. content of calcium carbonate in the product
For 25%.
In another embodiment, carbonic acid calcium-nutrition intensifying agent is 40% formulation, the i.e. content of calcium carbonate in the product
For 50%.
The foregoing is merely presently filed embodiment, not thereby limits the scope of the claims of the application, every to utilize this
The equivalent structure or equivalent flow shift that application specification and accompanying drawing content are made, it is relevant to be directly or indirectly used in other
Technical field, is similarly included in the scope of patent protection of the application.
Claims (10)
- A kind of 1. preparation method of carbonic acid calcium-nutrition intensifying agent, it is characterised in that including：Weigh at least one of calcium carbonate and lactose, microcrystalline cellulose and maltodextrin of preset quality percentage；The premixing of at least one of the calcium carbonate and lactose, microcrystalline cellulose or maltodextrin for being weighed is obtained pre- Batch mixing；The premix is smashed to obtain mixed-powder；The mixed-powder is uniformly mixed by mixer.
- 2. the preparation method of carbonic acid calcium-nutrition intensifying agent according to claim 2, it is characterised in that the preset quality Percentage is specially：Calcium carbonate：The mass percent of at least one of lactose, microcrystalline cellulose and maltodextrin is 1-95： 5-99；The prepared carbonic acid calcium-nutrition intensifying agent is the formulation of any one value in 1%-98%.
- 3. the preparation method of carbonic acid calcium-nutrition intensifying agent according to claim 1, it is characterised in that described to be weighed The step of calcium carbonate and at least one of lactose or the maltodextrin premixing obtains premix specifically includes：By alleged by At least one of the calcium carbonate and lactose, microcrystalline cellulose or maltodextrin for taking are added in mixer with default Mixing rate mixes preset time.
- 4. the preparation method of carbonic acid calcium-nutrition intensifying agent according to claim 3, it is characterised in that the default mixing speed Rate is 60-80r/min；The preset time 5-10min.
- 5. the preparation method of carbonic acid calcium-nutrition intensifying agent according to claim 1, it is characterised in that described by the premix The step of feed powder essence is to obtain mixed-powder specifically includes：The premix is added in disintegrating machine and is crushed to obtain smashing mesh number For mixed-powder described in 80-3500 purposes.
- 6. the preparation method of carbonic acid calcium-nutrition intensifying agent according to claim 1, it is characterised in that described by the mixing Powder by mixer be uniformly mixed including：The mixed-powder is added in mixer with the mixing rate mixing 8-15min of 60-80r/min.
- 7. the preparation method of carbonic acid calcium-nutrition intensifying agent according to claim 1, it is characterised in that described by the mixing Include after the step that powder is uniformly mixed by mixer：The mixed-powder after mixing is carried out once or multitime feedback.
- 8. the preparation method of carbonic acid calcium-nutrition intensifying agent according to claim 7, it is characterised in that the feed back time is big In 7min.
- A kind of 9. carbonic acid calcium-nutrition intensifying agent, it is characterised in that the raw material of the carbonic acid calcium-nutrition intensifying agent include calcium carbonate with And at least one of lactose, microcrystalline cellulose and maltodextrin；The carbonic acid calcium-nutrition intensifying agent is by such as claim 1- 7 any one of them preparation methods prepare gained.
- 10. carbonic acid calcium-nutrition intensifying agent according to claim 9, it is characterised in that the carbonic acid calcium-nutrition intensifying agent is Powdered, the crushing mesh number is any one value in 80-3500 mesh；The carbonic acid calcium-nutrition intensifying agent is in 1%-50% The formulation of any one value..
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