CN107951979A - Chinese medicine composition of the Bi Collettii containing Shan and preparation method thereof - Google Patents

Chinese medicine composition of the Bi Collettii containing Shan and preparation method thereof Download PDF

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CN107951979A
CN107951979A CN201711483589.5A CN201711483589A CN107951979A CN 107951979 A CN107951979 A CN 107951979A CN 201711483589 A CN201711483589 A CN 201711483589A CN 107951979 A CN107951979 A CN 107951979A
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parts
shan
chinese medicine
medicine composition
collettii
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廖厚知
杨坤
李家宝
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GUANGXI WANDE PHARMACEUTICAL CO Ltd
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GUANGXI WANDE PHARMACEUTICAL CO Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/69Polygalaceae (Milkwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/30Extraction of the material
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    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

The invention discloses the Chinese medicine composition of the Bi Collettii containing Shan, raw material is made of the traditional Chinese medicinal components of following parts by weight:30 60 parts of Shan Bi Collettiis, 10 30 parts of gymnema sylvestre, without 10 20 parts of ma rattan, 10 30 parts of false-yellowflower milkwort root or herb, 20 50 parts of purslane, 10 20 parts of longpeduncle kadsura stem.Prescription of the present invention is rigorous, has clearing heat and promoting diuresis, cool blood, the work(to replenish qi to invigorate the spleen, can obviously improve hyperglycaemia with more drink, diuresis, eat more, become thin, the tired symptom such as powerless, weakness of the spleen and the stomach of body, reparation islet function, to diabetes with it is good the effect of.

Description

Chinese medicine composition of the Bi Collettii containing Shan and preparation method thereof
Technical field
The invention belongs to medicine field, is related to Chinese medicine composition of a kind of Bi Collettii containing Shan and preparation method thereof.
Background technology
The category that diabetes spp is quenched one's thirst in the traditional Chinese medical science.Quench one's thirst be by drink more, one kind more characterized by food, diuresis, lean body mass Disease.The name quenched one's thirst, head are seen《The Yellow Emperor's Canon of Internal Medicine》,《Synopsis Golden Chamber》In will quench one's thirst and be divided into three types:Thirsty and more drink person is On disappear;Rapid digestion of food and polyorexia person disappears in being;Thirsty, urine such as cream person disappear under being.
The traditional Chinese medical science thinks that eating and drinking without temperance, disorder of emotion, labor, which are intended to the factors such as excessive, ferritic weakness, can cause to quench one's thirst.The disease The interpretation of the cause, onset and process of an illness is characterized in that the deficiency of Yin is scorching, using the deficiency of Yin as this, with scorching for mark, and both reciprocal causations:It is scorching that notably then the deficiency of Yin is more very, cloudy It is empty notably then it is scorching more very.The diseased region quenched one's thirst is attached most importance in lung, stomach and kidney with the lesion of kidney.If patient's dryness of the lung is cloudy Void, body fluid are lost in moistening, then the upper eliminating mass shape that mouth parched and tongue scorched, polydipsia are drunk more occurs;If patient's stomach excessive heat, digesting food Ability crosses Sheng, then the middle eliminating mass shape of polyorexia occurs;If patient's deficiency of kidney essence, it is impossible to constrain urine, then frequent micturition occurs More, turbid urine such as fat the lower eliminating mass shape of amount;If patient has the factor of the dryness of the lung, stomach energy and kidney deficiency concurrently, can occur more drinks, more at the same time The symptoms such as food, diuresis.The course of disease of diabetes is longer, with the passing of time the state of an illness of the patient is not usually cured, eventually because of impairment of both QI and YIN and There are other lesions in merging.Using clearing heat and promoting diuresis, cool blood, the treatment method to replenish qi to invigorate the spleen, scientific composition forms the present invention, right Diabetes have universal specific aim.In addition to the present invention there is not yet Shan Bi Collettiis, gymnema sylvestre, without ma rattan, false-yellowflower milkwort root or herb, dent Amaranth, the report of longpeduncle kadsura stem composition.
(1) Shan Bi Collettiis, this product are the dried root of Dioscoreaceae plant Shan Bi Collettii Mountain Yam Rhizome.【Nature and flavor】 Hardship, it is mild-natured.【Channel tropism】Enter liver, stomach, bladder warp.【Major function】Wind-damp dispelling, dampness removing are turbid.Cure mainly cream to drench, gonorrhoea, under band, sore, Eczema, arthralgia pain due to rheumatism.
(2) gymnema sylvestre, this product are the spray of Asclepiadaceae plant gymnema sylvestre Gymnema sylvestre (Retz.) Schult. Leaf.【Nature and flavor】It is flat;It is bitter.【Channel tropism】The heart;Liver;The spleen channel.【Major function】Clearing heat and cooling blood, apocenosis detumescence, relieves pain myogenic.Main rheumatism numbness Bitterly, abscess of throat, scrofula, acute mastitis, boil, eczema, nameless sores or boils;Venomous snake bite.
(3) without ma rattan, this product is the drying herb of canella dodder laurel Cassytha filiformis Linn..【Property Taste】Mildly bitter flavor, sweet, cool in nature, mild toxicity.【Channel tropism】Return liver, lung, kidney, bladder warp.【Major function】Clearing heat and promoting diuresis, removing pattogenic heat from the blood and toxic material from the body.It is main Cure cold fever, heat gonorrhea, urolithiasis, jaundice with damp-heat pathogen, diarrhea, dysentery, spitting of blood, bleeding from five sense organs or subcutaneous tissue, wind-fire red eye, traumatic injury, traumatic hemorrhage, Sore festers, scald, scabies tinea leprosy.
(4) false-yellowflower milkwort root or herb, this product are the drying of milk wort false-yellowflower milkwort root or herb Polygala fallax Hemsl. Root.【Nature and flavor】Sweet tea, slight bitter, put down.【Major function】Tonifying Qi and blood, invigorating spleen to remove dampness, promoting blood circulation for regulating menstruation.For physically weak after being ill, waist and knee acid Bitterly, treating rheumatic ostealgia, traumatic injury, icteric hepatitis, nephritic dropsy, rectal prolapse, the prolapse of uterus, leukorrhea, irregular menstruation, insomnia.
(5) purslane, this product are the drying overground part of portulacaceous plant purslane Portulaca oleracea L. Point.【Nature and flavor】Acid, trembles with fear.【Channel tropism】Return liver, large intestine channel.【Major function】It is clearing heat and detoxicating, remove heat from the blood and relieve diarrhea, dehumidify, it is treating stranguria.Main heat toxin Rush down dysentery, heat gonorrhea, renal shutdown, leukorrhea with reddish discharge, uterine bleeding, hemorrhoid blood, sore carbuncle furuncle, erysipelas, scrofula, wet tinea are white bald.
(6) longpeduncle kadsura stem, this product are Schisandraceae Plant China Schisandra chinensis Schisandrarubriflora (Franch.) Rehd.etWils. drying rattan and root.【Nature and flavor】Acid;It is warm-natured.【Channel tropism】Liver, lung, stomach.【Major function】Relaxing tendons and activating collaterals, Regulating qi-flowing for relieving pain, reinforcing spleen to promote digestion, astringes the lung and promotes the production of body fluid.Main traumatic injury, fracture, internal lesion caused by overexertion, lumbago due to wind-wetness evil, joint pain, dyspepsia are stagnated, stomach Bitterly, thirsty, irregular menstruation, infantile enuresis, scald are lacked in abdominal distension, chronic cough shortness of breath, Tianjin.
The disclosure of background above technology contents is only used for inventive concept and the technical solution that auxiliary understands the present invention, it is not The prior art of present patent application is necessarily belonged to, shows the applying date of the above in present patent application in no tangible proof In the case of disclosed, above-mentioned background technology should not be taken to the novelty and creativeness of evaluation the application.
The content of the invention
The object of the present invention is to provide the Chinese medicine composition and its system that can play treatment diabetes of a kind of Bi Collettii containing Shan Preparation Method.
The present inventor is combined with the advanced preparation technique of modern Chinese herbal medicine by the guidance of theory of traditional Chinese medical science, by reasonable preparation, A kind of Chinese medicine composition of Bi Collettii containing Shan is made, this Chinese medicine composition has clearing heat and promoting diuresis, cool blood, the work(to replenish qi to invigorate the spleen, can have Effect treatment diabetes, achieve the purpose that to solve patient suffering.
The technical solution adopted in the present invention is as follows:
The Chinese medicine composition of the Bi Collettii containing Shan, raw material are made of the traditional Chinese medicinal components of following parts by weight:30-60 parts of Shan Bi Collettiis, spoon 10-30 parts of custard rattan, without 10-20 parts of ma rattan, 10-30 parts of false-yellowflower milkwort root or herb, 20-50 parts of purslane, 10-20 parts of longpeduncle kadsura stem.
The Chinese medicine composition of the Bi Collettii described above containing Shan, raw material are preferably made of the traditional Chinese medicinal components of following parts by weight:Mountain Bi 40 parts of Collettii, 20 parts of gymnema sylvestre, without 15 parts of ma rattan, 20 parts of false-yellowflower milkwort root or herb, 30 parts of purslane, 15 parts of longpeduncle kadsura stem.
The Chinese medicine composition of the Bi Collettii described above containing Shan, the Chinese medicine composition can be prepared into pharmaceutically acceptable any Preparation.The Chinese medicine composition is preferably prepared to solid pharmaceutical preparation.The Chinese medicine composition is further preferably prepared into capsule.
The method that the Chinese medicine composition of the Bi Collettii described above containing Shan is prepared into capsule, it is characterised in that including following step Suddenly:
S1:Weigh by weight:30-60 parts of Shan Bi Collettiis, 10-30 parts of gymnema sylvestre, without 10-20 parts of ma rattan, false-yellowflower milkwort root or herb 10-30 parts, 20-50 parts of purslane, 10-20 parts of longpeduncle kadsura stem;
S2:By load weighted Shan Bi Collettiis, gymnema sylvestre, without ma rattan, false-yellowflower milkwort root or herb, purslane, longpeduncle kadsura stem, add 6-10 times Measure water boiling and extraction 2-3 time, when each 1-3 is small, filter, merging filtrate;
S3:By the filtrate after merging, thick paste is concentrated in vacuo to, adds starch, carboxymethyl cellulose sodium, is mixed, is pelletized, is done It is dry, add magnesium stearate, mix, load capsule, to obtain the final product.
The method that the Chinese medicine composition of the Bi Collettii described above containing Shan is prepared into capsule, the step S1 are preferably by weight Part weighs:40 parts of Shan Bi Collettiis, 20 parts of gymnema sylvestre, without 15 parts of ma rattan, 20 parts of false-yellowflower milkwort root or herb, 30 parts of purslane, longpeduncle kadsura stem 15 Part.
The method that the Chinese medicine composition of the Bi Collettii described above containing Shan is prepared into capsule, the thick paste is preferably 60-65 DEG C When relative density be 1.20-1.30 thick paste.
The Chinese medicine composition of the Bi Collettii described above containing Shan, the Chinese medicine composition answering in treatment diabetes medicament is prepared With.
The Chinese medicine composition of the Bi Collettii of the invention containing Shan is on the basis of traditional Chinese medicine traditional theory, is passed through with reference to medication among the people Test, be formulated with modern scientific theory.Fang Zhongshan Bi Collettiis, gymnema sylvestre have the turbid work(of wind-damp dispelling, dampness removing, are Fang Zhongjun Medicine;No ma rattan, false-yellowflower milkwort root or herb have heat-clearing, cool blood, the work(of tonifying Qi and blood, are all ministerial drug;Longpeduncle kadsura stem has qi-regulating, invigorating the spleen Work(, be adjutant;Purslane has effects that cool blood, dehumidifying;Purslane also known as five-element's grass, enter the five internal organs, and coordinating the drug actions of a prescription is to make medicine; All medicines share plays clearing heat and promoting diuresis, cool blood, the work(to replenish qi to invigorate the spleen altogether.Prescription of the present invention is rigorous, and it is special that medicine lacks power, can obviously improve high blood Sugar with more drink, diuresis, eat more, become thin, the tired symptom such as powerless, weakness of the spleen and the stomach of body, islet function is repaired, to diabetes with well The effect of.
Embodiment
With reference to specific embodiment, the invention will be further described, but does not limit the scope of the invention and apply Scope:
First, the preparation of capsule
Embodiment 1
The method that the Chinese medicine composition of the Bi Collettii containing Shan is prepared into capsule, comprises the following steps:
S1:Weigh by weight:Shan Bi Collettiis 30kg, gymnema sylvestre 10kg, without ma rattan 10kg, false-yellowflower milkwort root or herb 10kg, purslane 20kg, longpeduncle kadsura stem 10kg;
S2:By load weighted Shan Bi Collettiis, gymnema sylvestre, without ma rattan, false-yellowflower milkwort root or herb, purslane, longpeduncle kadsura stem, add 6 times of amounts Water boiling and extraction 3 times, every time 1 it is small when, filtration, merging filtrate;
S3:By the filtrate after merging, relative density is 1.20 thick paste when being concentrated in vacuo to 60 DEG C, adds starch, carboxylic first Base fiber sodium, mixes, and pelletizes, dry, adds magnesium stearate, mixes, and loads capsule, to obtain the final product.
Embodiment 2
The method that the Chinese medicine composition of the Bi Collettii containing Shan is prepared into capsule, comprises the following steps:
S1:Weigh by weight:Shan Bi Collettiis 60kg, gymnema sylvestre 30kg, without ma rattan 20kg, false-yellowflower milkwort root or herb 30kg, purslane 50kg, longpeduncle kadsura stem 20kg;
S2:By load weighted Shan Bi Collettiis, gymnema sylvestre, without ma rattan, false-yellowflower milkwort root or herb, purslane, longpeduncle kadsura stem, add 10 times of amounts Water boiling and extraction 2 times, every time 3 it is small when, filtration, merging filtrate;
S3:By the filtrate after merging, relative density is 1.30 thick paste when being concentrated in vacuo to 65 DEG C, adds starch, carboxylic first Base fiber sodium, mixes, and pelletizes, dry, adds magnesium stearate, mixes, and loads capsule, to obtain the final product.
Embodiment 3
The method that the Chinese medicine composition of the Bi Collettii containing Shan is prepared into capsule, comprises the following steps:
S1:Weigh by weight:Shan Bi Collettiis 40kg, gymnema sylvestre 20kg, without ma rattan 15kg, false-yellowflower milkwort root or herb 20kg, purslane 30kg, longpeduncle kadsura stem 15kg;
S2:By load weighted Shan Bi Collettiis, gymnema sylvestre, without ma rattan, false-yellowflower milkwort root or herb, purslane, longpeduncle kadsura stem, add 6-10 times Measure water boiling and extraction 3 times, every time 2 it is small when, filtration, merging filtrate;
S3:By the filtrate after merging, relative density is 1.25 thick paste when being concentrated in vacuo to 62 DEG C, adds starch, carboxylic first Base fiber sodium, mixes, and pelletizes, dry, adds magnesium stearate, mixes, and loads capsule, to obtain the final product.
2nd, clinical practice
The Chinese medicine composition of the Bi Collettii of the invention containing Shan, was once used to treating and observing 86 diabetics.By above-mentioned preparation 3 kinds of good embodiment samples, be respectively used to hyperglycaemia with more drink, diuresis, eat more, become thin, the tired symptom such as powerless, weakness of the spleen and the stomach of body Patient's (man 30, female 26, average age 52 years old).The results detailed in Table 1.
1 clinical application effect table of table
Embodiment Fully recover (%) Improve (%) Invalid (%)
Embodiment 1 (30 people) 80 13 7
Embodiment 2 (28 people) 82 11 7
Embodiment 3 (28 people) 86 11 4
The result shows that:It is safe to use, effective using the Chinese medicine composition of present invention Bi Collettii containing Shan, there is clearing heat and promoting diuresis, cool Blood, the work(to replenish qi to invigorate the spleen, can obviously improve hyperglycaemia with more drink, diuresis, eat more, become thin, the tired disease such as powerless, weakness of the spleen and the stomach of body Shape, repairs islet function, has the effect of good to diabetes.It is several model cases below:
Case 1:Zhao's ××, man, 42 years old, to drink more, more food, diuresis and become thin, fatigue and asthenia is cardinal symptom, through hospital Inspection is diagnosed as type i diabetes.Capsule (embodiment 1) made of the Chinese medicine composition of the Bi Collettii containing Shan of the invention is taken, every time 3 Grain (0.5g/), 3 times a day, 7 as a treatment course, takes two courses for the treatment of, and symptom is wholly absent, recovery from illness.
Case 2:Grandson's ××, female, 47 years old, conscious weak, apathetic, preprandial glucose deficiency, postprandial blood sugar are big after testing In standard value, hospital diagnosis is type ii diabetes.Take tablet (embodiment made of the Chinese medicine composition of the Bi Collettii of the invention containing Shan 2) 7,3 tablets each time (0.5g/), 3 times a day, are even served, antisecosis, rear blood sugar recovery is normal before the meal, recovery from illness.
Case 3:Perhaps ××, man, 38 years old, for type i diabetes and has hypertension through hospital diagnosis.Take the Chinese medicine of the present invention Capsule made of composition (embodiment 3), 3 tablets each time (0.5g/), 3 times a day, even served 20, diabetic symptom disappears substantially Lose, blood glucose drops to normal level (empty stomach 5.0mmol/l, postprandial 5.8mmol/l), and blood pressure is dropped to by 120/165mmHg 100/130mmHg。
Case 4:Poplar ××, female, 45 years old, hyperglycaemia companion became thin, body is tired powerless, weakness of the spleen and the stomach, fasting blood-glucose 13.4mmol/ L, it is postprandial 2 it is small when blood glucose 18.4mmol/l.The embodiment of the present invention 3 is taken, 3 tablets each time (0.5g/), 3 times a day, even served 30 Day, blood glucose drops to normal level (empty stomach 4.9mmol/l, postprandial 5.5mmol/l), and appetite increases, weight gain, and face is red Profit, energetic, recovery from illness.
Above content is to combine specific/preferred embodiment further description made for the present invention, it is impossible to Assert that the specific implementation of the present invention is confined to these explanations.Come for general technical staff of the technical field of the invention Say, without departing from the inventive concept of the premise, it can also make some replacements or modification to the embodiment that these have been described, And these are substituted or variant should all be considered as belonging to protection scope of the present invention.

Claims (9)

1. the Chinese medicine composition of the Bi Collettii containing Shan, it is characterised in that raw material is made of the traditional Chinese medicinal components of following parts by weight:Shan Bi Collettiis 30-60 parts, 10-30 parts of gymnema sylvestre, without 10-20 parts of ma rattan, 10-30 parts of false-yellowflower milkwort root or herb, 20-50 parts of purslane, longpeduncle kadsura stem 10-20 parts.
2. the Chinese medicine composition of the Bi Collettii containing Shan according to claim 1, it is characterised in that raw material by following parts by weight Chinese medicine Component forms:40 parts of Shan Bi Collettiis, 20 parts of gymnema sylvestre, without 15 parts of ma rattan, 20 parts of false-yellowflower milkwort root or herb, 30 parts of purslane, longpeduncle kadsura stem 15 parts.
3. the Chinese medicine composition of the Bi Collettii containing mountain according to claim 1, it is characterised in that the Chinese medicine composition prepares patent medicine Acceptable any preparation on.
4. the Chinese medicine composition of the Bi Collettii containing Shan according to claim 1, it is characterised in that the Chinese medicine composition is prepared into solid Body preparation.
5. the Chinese medicine composition of the Bi Collettii containing mountain according to claim 1, it is characterised in that the Chinese medicine composition prepares plastic Wafer.
6. the method that the Chinese medicine composition of the Bi Collettii containing Shan is prepared into capsule as claimed in claim 1, it is characterised in that including with Lower step:
S1:Weigh by weight:30-60 parts of Shan Bi Collettiis, 10-30 parts of gymnema sylvestre, without 10-20 parts of ma rattan, false-yellowflower milkwort root or herb 10-30 Part, 20-50 parts of purslane, 10-20 parts of longpeduncle kadsura stem;
S2:By load weighted Shan Bi Collettiis, gymnema sylvestre, without ma rattan, false-yellowflower milkwort root or herb, purslane, longpeduncle kadsura stem, add 6-10 times to measure water Extraction 2-3 time is decocted, when each 1-3 is small, is filtered, merging filtrate;
S3:By the filtrate after merging, thick paste is concentrated in vacuo to, adds starch, carboxymethyl cellulose sodium, is mixed, is pelletized, it is dry, add Enter magnesium stearate, mix, load capsule, to obtain the final product.
7. the method that the Chinese medicine composition of the Bi Collettii containing Shan is prepared into capsule according to claim 6, it is characterised in that described Step S1 is to weigh by weight:40 parts of Shan Bi Collettiis, 20 parts of gymnema sylvestre, without 15 parts of ma rattan, 20 parts of false-yellowflower milkwort root or herb, purslane 30 Part, 15 parts of longpeduncle kadsura stem.
8. the method that the Chinese medicine composition of the Bi Collettii containing Shan is prepared into capsule according to claim 6, it is characterised in that described The thick paste that relative density is 1.20-1.30 when thick paste is 60-65 DEG C.
9. the Chinese medicine composition of the Bi Collettii containing Shan according to claim 1, it is characterised in that the Chinese medicine composition is controlled in preparation Treat the application in diabetes medicament.
CN201711483589.5A 2017-12-29 2017-12-29 Chinese medicine composition of the Bi Collettii containing Shan and preparation method thereof Pending CN107951979A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104383123A (en) * 2014-11-14 2015-03-04 程金生 Method for preparing golden camellia lipid-lowering blood sugar-reducing preparation

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN104383123A (en) * 2014-11-14 2015-03-04 程金生 Method for preparing golden camellia lipid-lowering blood sugar-reducing preparation

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朱家谷等: "匙羹藤复方冲剂降糖降脂作用研究", 《中成药》 *
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