CN107929679A - A kind of new medicine composition for treating gasteremphraxis and preparation method thereof - Google Patents

A kind of new medicine composition for treating gasteremphraxis and preparation method thereof Download PDF

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CN107929679A
CN107929679A CN201711024173.7A CN201711024173A CN107929679A CN 107929679 A CN107929679 A CN 107929679A CN 201711024173 A CN201711024173 A CN 201711024173A CN 107929679 A CN107929679 A CN 107929679A
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medicine composition
chinese
gasteremphraxis
treating
raddle
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罗兴贵
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Sichuan Xingjujiao Medical Technology Co Ltd
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger

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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of new medicine composition for treating gasteremphraxis according to the understanding mechanism of Chinese traditional treatment gasteremphraxis, each component and its mass parts ratio of the Chinese medicine composition are as follows:50~150g of the tuber of pinellia, 50~180g of Rhizoma Atractylodis Macrocephalae, 50~180g of bletilla, 50~150g of the membrane of a chicken's gizzard, 150~350g of Chinese yam, 150~300g of Radix Codonopsis, 30~120g of rhizoma zingiberis, 150~320g of raddle, 50~120g of radish seed, 60~160g of Radix Paeoniae Alba, 30~120g of Cortex Magnoliae Officinalis, 30~150g of dried orange peel, 100~180g of Poria cocos, medicine provided by the invention are a good Chinese prescriptions.

Description

A kind of new medicine composition for treating gasteremphraxis and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of new medicine composition for treating gasteremphraxis, particularly supplies The field of the new medicine composition that gasteremphraxis patient uses and preparation method thereof.
Background technology
Doctor thinks:One of gasteremphraxis, name of disease, abdominal distension.Main symptom turgor, epigastric pain.The reason for causing gasteremphraxis have it is various, Such as, daily life system is irregular, and diet is unhygienic etc..
The physiological function of stomach is mainly:Temporarily storage food and digestion food.The process that food is entered small intestine by stomach is known as The emptying of stomach.5min has begun to part and has been discharged into duodenum generally after food enters stomach.The speed of different food emptyings is not Together, food is mixed to be emptied completely by stomach it is generally necessary to 4~6h.
The emptying of stomach depends primarily upon pylorus both sides(In stomach and in duodenum)Pressure differential.Emptying of the food in stomach Stomach is caused to move in journey, so as to produce gastric retention table.When gastric retention table is more than duodenum internal pressure, food can be discharged by stomach.Instead It, the suppression that duodenum content moves stomach then slows down the emptying of stomach.In pathological conditions, when Stomach duodenum exists When inflammation, reflux, tumour or gastric juice, duodenal juice component change, it will delay the emptying of stomach, food is constantly to stomach Wall produces pressure;Meanwhile food produces a large amount of gases in stomach after excessive fermentation, intragastric pressure is further increased, thus just There is glutted, the constriction of upper abdomen, i.e. gasteremphraxis, for theory of traditional Chinese medical science, the generation of gasteremphraxis is mainly due to the various causes of disease Stomach internal organs is influenced, stomach Qi is stagnated and is formed in gastral cavilty from normal and drop, mechanism of qi.
So, a kind of Chinese medicine composition that can effectively treat gasteremphraxis how is just found, is that those skilled in the art urgently will Solve the problems, such as.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment gasteremphraxis, people gradually appreciate Chinese traditional treatment stomach The advantages of swollen, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment gasteremphraxis Present situation, it is extensive early to solve gasteremphraxis patient the purpose of the invention is to provide a kind of new medicine composition for treating gasteremphraxis The problem of rehabilitation health.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can effectively be controlled Treat above-mentioned gasteremphraxis.
To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is:There is provided and a kind of treat the new of gasteremphraxis Chinese medicine composition and preparation method thereof, it is characterised in that each component and mass parts of the Chinese medicine composition are than as follows:
50~150g of the tuber of pinellia, 50~180g of Rhizoma Atractylodis Macrocephalae, 50~180g of bletilla, 50~150g of the membrane of a chicken's gizzard, 150~350g of Chinese yam, Radix Codonopsis 150~300g, 30~120g of rhizoma zingiberis, 150~320g of raddle, 50~120g of radish seed, 60~160g of Radix Paeoniae Alba, Cortex Magnoliae Officinalis 30~ 120g, 30~150g of dried orange peel, 100~180g of Poria cocos, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
A kind of new medicine composition for treating gasteremphraxis and preparation method thereof, it is characterised in that the Chinese medicine composition Each component and mass parts are than as follows:
58~130g of the tuber of pinellia, 58~150g of Rhizoma Atractylodis Macrocephalae, 58~160g of bletilla, 58~130g of the membrane of a chicken's gizzard, 180~310g of Chinese yam, Radix Codonopsis 180~260g, 38~105g of rhizoma zingiberis, 180~260g of raddle, 58~105g of radish seed, 70~140g of Radix Paeoniae Alba, Cortex Magnoliae Officinalis 38~ 105g, 38~130g of dried orange peel, 115~160g of Poria cocos, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
A kind of new medicine composition for treating gasteremphraxis and preparation method thereof, it is characterised in that the Chinese medicine composition Each component and mass parts are than as follows:
Tuber of pinellia 115g, Rhizoma Atractylodis Macrocephalae 130g, bletilla 140g, the membrane of a chicken's gizzard 115g, Chinese yam 260g, Radix Codonopsis 230g, rhizoma zingiberis 95g, raddle 230g, radish seed 95g, Radix Paeoniae Alba 120g, Cortex Magnoliae Officinalis 95g, dried orange peel 115g, Poria cocos 140g, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and Appropriate starch.
A kind of new medicine composition for treating gasteremphraxis and preparation method thereof, it is characterised in that the Chinese medicine composition Each component and mass parts are than as follows:
A, after above-mentioned raw materials Chinese medicine being picked impurity and dust, it is ground into according to mass parts than altogether(30~50 mesh)Graininess bag Decoct;
B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and soaks 50min, then soaked medicine is put into marmite again, The cold boiling water for adding 7~9 times of raw material Chinese medicine weight carries out first time high heat decoction, when 18min is arrived in decoction, turns slow boiling and boils 125min, leaching liquid;2. the cold boiling water for adding 6~8 times of raw material Chinese medicine weight in the dregs of a decoction again is fried by intense fire for the second time Boil, when 15min is arrived in decoction, turn slow boiling and boil 115min, leaching liquid;3. liquid mixing twice is condensed into relative density is 1.08 clear cream, it is then dry, grind with it is after disinfection to reserve;
C, the method for 1. preparing Chinese medicine capsules according to tradition, after smalls sieving ground in B, adds suitable micro mist silicon Glue, microcrystalline cellulose and starch are uniformly mixed, and are then prepared into capsule(Total length is 23.3mm after its capsule is sealed, medicinal powder Capacity 0.4~0.5g/), 2. then polish, sterilize, sealed packaging.
A kind of new medicine composition for treating gasteremphraxis and preparation method thereof, it is characterised in that the instructions of taking is:Will The capsule medicine prepared is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 4g(8)/ time, warm water delivery service, 3 Days as a treatment course, 2~3 courses for the treatment of of taking medicine, symptom all disappear, and disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention has in detail in Chinese Pharmacopoeia, Chinese medicine voluminous dictionary and China's book on Chinese herbal medicine Thin record.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component:
The tuber of pinellia, nature and flavor:It is acrid flavour, warm-natured, it is poisonous, there is the effect of eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, for treating cough Breathe heavily abundant expectoration, vomiting gastric disorder causing nausea, feeling of oppression and fullness in the chest and epigastrium dizziness of having a headache, uneasy sleeping at night, gall subcutaneous nodule, swollen ulcer drug;
Rhizoma Atractylodis Macrocephalae, nature and flavor:It is bitter, sweet, warm-natured, there is the effect of strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, tocolysis, for treating temper Weakness, spiritlessness and weakness, deficiency of food lack thin abdominal distension, big loose stool, fluid retention stagnating in the interior, difficult urination, oedema, phlegmatic vertigo, warm numbness are ached, gas Empty spontaneous perspiration, fetal irritability;
Bletilla, nature and flavor:It is bitter sweet, cool, there is the effect of tonifying lung, hemostasis, detumescence, myogenic, sore, hinder hemoptysis, nosebleed for treating lung Blood, metal-inflicted wound bleeding, swollen ulcer drug, canker sores, soup fire burn, rhagadia manus et pedis;
The membrane of a chicken's gizzard, nature and flavor:It is sweet, flat, there is the effect of disperse accumulation is stagnant, strengthening the spleen and stomach, for treat dyspepsia turgor, vomiting gastric disorder causing nausea, rush down dysentery, Infantile malnutrition due to digestive disturbances or intestinalparasites, quench one's thirst, lose excessive, larynx numbness acute tonsillitis, noma aphtha;
Chinese yam, nature and flavor:It is sweet, flat, have tonifying spleen, support lung, reinforce the kidney, strengthening the essence the effect of, for treat splenasthenic diarrhea, deficiency of food edema, Deficiency syndrome of the lung cough and asthma, quench one's thirst, pass out semen, with, kidney deficiency frequent micturition, and the diseases such as carbuncle swells, scrofula are controlled in external application;
Radix Codonopsis, nature and flavor:It is sweet in flavor, mild-natured, there is the effect of strengthening the spleen and tonifying the lung, nourishing generate fluid, for treating weakness of the spleen and the stomach, deficiency of food just Half congealed, limbs fatigue, the deficiency syndrome of the lung are breathed with cough, shortness of breath and spontaneous perspiration, gas micro- two lose;
Rhizoma zingiberis, nature and flavor:Acrid flavour, property heat, have the effect of warming spleen and stomach for dispelling cold, Back to Yang Tongmai, Wenfei of drink, cold for treating gastral cavity abdomen Bitterly, vomiting, diarrhea, yang depletion faint inverse, cold drink breath with cough, numbness and ache of cold dampness;
Raddle, nature and flavor:Bitter, sweet, cold nature, have the effect of calming the liver, important city drop is inverse, cooling blood and hemostasis, for treating Headache, dizziness, palpitaition, demented, frightened epilepsy, vomiting, gas, hiccup, dysphagic, cough, asthma, haematemesis, nosebleed epistaxis, uterine bleeding, have blood in stool, urinate The diseases such as blood;
Radish seed, nature and flavor:It is acrid flavour, sweet, mild-natured, there is the effect of promoting digestion, lowering the adverse-rising QI to resolve phlegm, for treating stagnation of QI due to dyspepsia, gastral cavity Weight, cough ant phlegm, circulation of vital energy in the wrong direction asthma are full after distention and fullness in the abdomen, diarrhea, diarrhea;
Radix Paeoniae Alba, nature and flavor:Bitter, acid, be slightly cold, and has the effect of smooth liver and relieve pain, nourishing blood for regulating menstruation, astringing YIN to stop sweating, dizzy for treating headache The disease such as dizzy, hypochondriac pain, abdominal pain, four limbs contraction pain, blood deficiency chlorosis, irregular menstruation, spontaneous perspiration, night sweat;
Cortex Magnoliae Officinalis, nature and flavor:It is bitter, pungent, warm-natured, there is the effect of gas consumption product, eliminating dampness except full, relieving asthma, for treating dyspepsia gas Stagnant, abdominal distention constipation, damp retention in middle-jiao, abdominal swelling and diarrhea, phlegm stops up the circulation of vital energy in the wrong direction, chest full of cough;
Dried orange peel, nature and flavor:It is acrid flavour, hardship, warm-natured, have qi-regulating and in, it is eliminating dampness and eliminating phlegm, the effect of sharp water defaecation, for treating taste Discord, abdominal distention, do not feel like eating, vomiting hiccup, phlegm-damp obstructing lung, coughing with a lot of sputum, chest diaphragm expire vexed, vertigo, oedema, urine The diseases such as unfavorable, constipation, acute mastitis mange, middle ichthyophagy crab poison, wine poison;
Poria cocos, nature and flavor:It is sweet, light, flat, have eliminating dampness and diuresis, strengthening the spleen and stomach, antitoxic heart-soothing and sedative the effect of, for treat difficult urination, Oedema turgor, phlegm and retained fluid cough are inverse, vomiting, spleen eating less, diarrhea, palpitation and restlessness, insomnia forgetfulness, seminal emission gonorrhoea.
Medicine of the present invention is the principle based on Chinese traditional treatment gasteremphraxis, is recognized from the pathomechanism according to gasteremphraxis and pharmacological action For:With regard to gasteremphraxis, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good effect to above-mentioned disease.
Embodiment
A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned gasteremphraxis, the medicine prepared using the formula Good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific implementation of the present invention Mode is described in further detail:
Embodiment 1:
A kind of new medicine composition for treating gasteremphraxis, it is characterised in that each component and mass parts of the Chinese medicine composition Than as follows:
Tuber of pinellia 115g, Rhizoma Atractylodis Macrocephalae 130g, bletilla 140g, the membrane of a chicken's gizzard 115g, Chinese yam 260g, Radix Codonopsis 230g, rhizoma zingiberis 95g, raddle 230g, radish seed 95g, Radix Paeoniae Alba 120g, Cortex Magnoliae Officinalis 95g, dried orange peel 115g, Poria cocos 140g, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and Appropriate starch.
Embodiment 2:
A kind of new medicine composition for treating gasteremphraxis, it is characterised in that each component and mass parts of the Chinese medicine composition Than as follows:
Tuber of pinellia 130g, Rhizoma Atractylodis Macrocephalae 150g, bletilla 160g, the membrane of a chicken's gizzard 130g, Chinese yam 310g, Radix Codonopsis 260g, rhizoma zingiberis 105g, raddle 260g, radish seed 105g, Radix Paeoniae Alba 140g, Cortex Magnoliae Officinalis 105g, dried orange peel 130g, Poria cocos 160g, auxiliary material:Superfine silica gel powder, microcrystalline cellulose It is appropriate with starch.
Embodiment 3:
A kind of new medicine composition for treating gasteremphraxis, it is characterised in that each component and mass parts of the Chinese medicine composition Than as follows:
Tuber of pinellia 150g, Rhizoma Atractylodis Macrocephalae 180g, bletilla 180g, the membrane of a chicken's gizzard 150g, Chinese yam 350g, Radix Codonopsis 300g, rhizoma zingiberis 120g, raddle 320g, radish seed 120g, Radix Paeoniae Alba 160g, Cortex Magnoliae Officinalis 120g, dried orange peel 150g, Poria cocos 180g, auxiliary material:Superfine silica gel powder, microcrystalline cellulose It is appropriate with starch.
Model case
Through clinical conditions gasteremphraxis patient totally 1490, the age is 825 of more than 41 years old, and only 635 are less than 41 years old. 840 to fully recover in 1490 patients, effective 531, invalid 119.Total effective rate is up to 92%.

Claims (3)

1. a kind of new medicine composition for treating gasteremphraxis, it is characterised in that each component and its matter of the Chinese medicine composition Part is measured than as follows:
50~150g of the tuber of pinellia, 50~180g of Rhizoma Atractylodis Macrocephalae, 50~180g of bletilla, 50~150g of the membrane of a chicken's gizzard, 150~350g of Chinese yam, Radix Codonopsis 150~300g, 30~120g of rhizoma zingiberis, 150~320g of raddle, 50~120g of radish seed, 60~160g of Radix Paeoniae Alba, Cortex Magnoliae Officinalis 30~ 120g, 30~150g of dried orange peel, 100~180g of Poria cocos, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
2. the new medicine composition for the treatment of gasteremphraxis according to claim 1, it is characterised in that the Chinese medicine composition Each component and its mass parts are than as follows:
58~130g of the tuber of pinellia, 58~150g of Rhizoma Atractylodis Macrocephalae, 58~160g of bletilla, 58~130g of the membrane of a chicken's gizzard, 180~310g of Chinese yam, Radix Codonopsis 180~260g, 38~105g of rhizoma zingiberis, 180~260g of raddle, 58~105g of radish seed, 70~140g of Radix Paeoniae Alba, Cortex Magnoliae Officinalis 38~ 105g, 38~130g of dried orange peel, 115~160g of Poria cocos, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
3. the new medicine composition of the treatment gasteremphraxis according to claim 1 to 2, it is characterised in that the Chinese traditional medicine composition The each component and its mass parts of thing are than as follows:
Tuber of pinellia 115g, Rhizoma Atractylodis Macrocephalae 130g, bletilla 140g, the membrane of a chicken's gizzard 115g, Chinese yam 260g, Radix Codonopsis 230g, rhizoma zingiberis 95g, raddle 230g, radish seed 95g, Radix Paeoniae Alba 120g, Cortex Magnoliae Officinalis 95g, dried orange peel 115g, Poria cocos 140g, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and Appropriate starch.
CN201711024173.7A 2017-10-27 2017-10-27 A kind of new medicine composition for treating gasteremphraxis and preparation method thereof Withdrawn CN107929679A (en)

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