CN107929619A - Lotion for gynaecological imflammation and preparation method thereof - Google Patents

Lotion for gynaecological imflammation and preparation method thereof Download PDF

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Publication number
CN107929619A
CN107929619A CN201711479782.1A CN201711479782A CN107929619A CN 107929619 A CN107929619 A CN 107929619A CN 201711479782 A CN201711479782 A CN 201711479782A CN 107929619 A CN107929619 A CN 107929619A
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parts
lotion
gynaecological imflammation
wild chrysanthemum
bark
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周鸿�
杨坤
李家宝
廖厚知
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GUANGXI WANDE PHARMACEUTICAL CO Ltd
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GUANGXI WANDE PHARMACEUTICAL CO Ltd
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
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Abstract

The invention discloses lotion for gynaecological imflammation and preparation method thereof, raw material is made of the traditional Chinese medicinal components of following parts by weight:20 50 parts of Chinese knotweed, 10 30 parts of smilax, 10 20 parts of grass-leaved sweetflag, 10 30 parts of iron holly bark, 10 30 parts of moutan bark, 10 20 parts of wild chrysanthemum, 10 20 parts of Cortex Phellodendri.The present invention is investigated the preparation method of the lotion.Lotion prescription of the present invention is rigorous, has clearing heat and detoxicating, swelling and pain relieving, the antipruritic work(of desinsection, has the effect of good to skin disease and gynaecological imflammation.

Description

Lotion for gynaecological imflammation and preparation method thereof
Technical field
The invention belongs to medicine field, is related to a kind of lotion for gynaecological imflammation and preparation method thereof.
Background technology
Gynaecological imflammation is the common disease of women, is primarily referred to as the inflammation of female sex organ, specifically includes female vulva Inflammation, vaginitis, cervicitis, pelvic infecton, common sympton are mainly vulva and pruritus of vagina, and locally generation is rotten to the corn for some, companion's cusalgia, Odynuria, frequent micturition, vaginal fluid increase, redness etc..Since many women lack due cognition and self body to gynecological disease Body protective awareness, plus various Bad habits etc., causes some female sections to be eaten up with illness, does not recover for a long time or again and again, give Normal life, work bring great inconvenience, or even influence family's wellbeing life.The present invention has gynaecological imflammation exclusive Specific aim, can effectively reduce patient suffering, improve the quality of living.Chinese knotweed of the present invention, wild chrysanthemum, stone Chang are had not yet to see Pu, smilax, iron holly bark, moutan bark, the report of Cortex Phellodendri composition.
(1) Chinese knotweed, this product are the drying herb of polygonaceae plant Chinese knotweed Polygonum chinense Linn..【Property Taste】It is pungent;It is bitter;It is cool in nature;【Major function】Clearing heat and promoting diuresis;Removing pattogenic heat from the blood and toxic material from the body;Flat liver improving eyesight;Activate blood and relax tendons.Main dysentery;Diarrhea;Throat Swelling and pain;Diphtheria;Cough with lung heat;Pertussis;Hepatitis;Under band;Cancerous swelling;Tympanitis;Eczema;Dizziness and tinnitus;Nebula;Bruise is damaged Wound.
(2) wild chrysanthemum, this product are the dry capitulum of feverfew mother chrysanthemum Chrysanthemum indicum L.. 【Nature and flavor】Toil, it is cool.【Channel tropism】:Return lung, liver.【Major function】Wind and heat dispersing, subdhing swelling and detoxicating.Control anemopyretic cold, it is pneumonia, white Larynx, gastroenteritis:Hypertension, malignant boil, carbuncle, aphtha, erysipelas, eczema, epidemic blisters.
(3) grass-leaved sweetflag, this product are the dry root of acorus gramineus araceae plant Acorus tatarinowii Schott Stem.【Nature and flavor】Acrid flavour;It is bitter;Slightly warm in nature.【Channel tropism】The heart;Liver;The spleen channel.【Major function】Dissipating phlegm for resuscitation;Dampness elimination promoting the circulation of qi;Wind-dispelling profit Numbness;Swelling and pain relieving.Main pyreticosis coma;Coma due to blocking of the respiratory system;It is forgetful;Tinnitus;It is deaf;Abdominal distention;Dysentery with vomiting;Arthralgia pain due to rheumatism;Traumatic injury; Ulcer mange.
(4) smilax, is the dry rhizome of liliaceous plant smilacis glabra Smilax glabra Roxb..【Nature and flavor】Sweet, It is light, put down.【Channel tropism】Return liver, stomach.【Major function】Dehumidifying, removing toxic substances is easing joint movement.For damp and hot stranguria with turbid discharge, under band, carbuncle swells, scrofula Limbs contraction caused by scrofula, mange, syphilis and mercury poisoning, arthralgia and myalgia.
(5) iron holly bark, is the dry bark of holly plant ilexrotunda Ilex rotunda Thunb..【Nature and flavor】It is bitter; It is cold.【Channel tropism】Lung;Liver;Large intestine channel.【Major function】It is clearing heat and detoxicating;Dampness removing;Analgesic.Main cold, fever;Abscess of throat;Stomachache; Affix one's name to wet diarrhea;Jaundice;Dysentery;Traumatic injury;Arthralgia pain due to rheumatism;Eczema;Boil.
(6) moutan bark, this product are the dry root skin of ranunculaceae peony Paeonia suffruticosa Andr.. 【Nature and flavor】It is bitter, pungent, it is slightly cold.【Channel tropism】The thoughts of returning home, liver and kidney channel.【Major function】Clearing heat and cooling blood, it is promoting blood circulation and removing blood stasis.For febrile virulent maculae, Hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to yin, closed dysmenorrhea, carbuncle sore tumefacting virus, the pain of injury caused by falling and tumbling.
(7) Cortex Phellodendri, this product are rutaceae wampee Phellodendron chinense Schneid. or cork tree The dry bark of Phellodendron amurense Rupr..【Nature and flavor】Hardship, trembles with fear.【Channel tropism】Return kidney, bladder warp.【Function master Control】Heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment.For damp-heat dysentery, jaundice, under band, heat gonorrhea, tinea pedis, impotence { wards off }, hectic fever due to yin labor Heat, night sweat, seminal emission, sore swollen toxin, eczema itch.
The disclosure of background above technology contents is only used for inventive concept and the technical solution that auxiliary understands the present invention, it is not The prior art of present patent application is necessarily belonged to, shows the applying date of the above in present patent application in no tangible proof In the case of disclosed, above-mentioned background technology should not be taken to the novelty and creativeness of evaluation the application.
The content of the invention
The object of the present invention is to provide a kind of lotion for gynaecological imflammation, which can prevent skin disease and treatment gynaecology Disease and other effects.The present inventor is combined, by excavating the people by the guidance of theory of traditional Chinese medical science with the advanced preparation technique of modern Chinese herbal medicine Between medication carry out reasonable preparation, a kind of lotion for gynaecological imflammation is made, it is antipruritic with clearing heat and detoxicating, swelling and pain relieving, desinsection The effect of, the diseases such as clean skin, prevention skin disease and treatment gynaecological imflammation can be effectively played, effectively mitigates patient suffering, reaches and carry The purpose of high quality of life.
The technical solution adopted in the present invention is as follows:
A kind of lotion for gynaecological imflammation, raw material are made of the traditional Chinese medicinal components of following parts by weight:20-50 parts of Chinese knotweed, 10-30 parts of smilax, 10-20 parts of grass-leaved sweetflag, 10-30 parts of iron holly bark, 10-30 parts of moutan bark, 10-20 parts of wild chrysanthemum, Cortex Phellodendri 10- 20 parts;
Its preparation method is:The raw material of above ratio is weighed, then it is 0.1- to weigh raw material gross weight percentage described above The E- polylysines that 0.3% borneol, raw material gross weight percentage described above are 0.2-0.5%;By load weighted wild chrysanthemum, Grass-leaved sweetflag, when adding 6 times of amount water distillating extracting oils 3 small, it is spare to collect distillate, liquid;Take Chinese knotweed, smilax, rescue must Should, moutan bark, Cortex Phellodendri and wild chrysanthemum and wild chrysanthemum, the grass-leaved sweetflag dregs of a decoction described in step S3, add water to cook, filter, merging filtrate, Add the liquid described in step S3, be concentrated into thick paste, to obtain the final product;In the thick paste, the distillate is added, stirs evenly, puts Put overnight, filtration, filtrate adds borneol, E- polylysines, stirs evenly, to obtain the final product.
The above is used for the lotion of gynaecological imflammation, and the raw material is preferably made of the traditional Chinese medicinal components of following parts by weight:Fire 40 parts of charcoal mother, 15 parts of smilax, 15 parts of grass-leaved sweetflag, 20 parts of iron holly bark, 20 parts of moutan bark, 15 parts of wild chrysanthemum, 18 parts of Cortex Phellodendri.
The above is used for the lotion of gynaecological imflammation, in the Chinese medicine composition, is preferably added to the Chinese medicine composition Borneol, the E- polylysines of 0.2-0.3% that total weight percent is 0.2%.
The above is used for the lotion of gynaecological imflammation, and described " adding water to cook " is preferably to add 8-15 times to decoct 1-3 times;Institute When to state decocting time be preferably each 0.5-3 small.
The preparation method of the lotion for gynaecological imflammation described in more than one, comprises the following steps:
S1:Weigh by weight:Take 20-50 parts of Chinese knotweed, 10-30 parts of smilax, 10-20 parts of grass-leaved sweetflag, iron holly bark 10- 30 parts, 10-30 parts of moutan bark, 10-20 parts of wild chrysanthemum, 10-20 parts of Cortex Phellodendri, clean, it is dry;
S2:Weigh medicinal material total weight percent described in step S1 be the borneol of 0.1-0.3%, medicinal material gross weight described in step S1 Measure the E- polylysines that percentage is 0.2-0.5%;
S3:By load weighted wild chrysanthemum, grass-leaved sweetflag, when adding 6 times of amount water distillating extracting oils 3 small, distillate, medicine are collected Liquid is spare, the dregs of a decoction are incorporated to S4 steps;
S4:Take Chinese knotweed, smilax, iron holly bark, moutan bark, Cortex Phellodendri and wild chrysanthemum and wild chrysanthemum, stone described in step S3 The calamus dregs of a decoction, add 8-15 times of water to decoct 1-3 times, and when each 0.5-3 is small, filtration, merging filtrate, adds the medicine described in step S3 Liquid, is concentrated into thick paste, to obtain the final product;
S5:In the thick paste described in step S4, the distillate described in step S3 is added, stirs evenly, stands overnight, filtered, filter Liquid adds borneol, E- polylysines, stirs evenly, to obtain the final product.
The preparation method of the above-described lotion for gynaecological imflammation, relative density is when the thick paste is 60 DEG C 1.25-1.35。
The preparation method of the above-described lotion for gynaecological imflammation, the step S4 preferably add 10 times of decoctions of water.
The preparation method of the above-described lotion for gynaecological imflammation, the step S4 are preferably added water to cook 2 times.
The preparation method of the above-described lotion for gynaecological imflammation, when the step S4 decocting times are preferably 2 small/ It is secondary.
The above-described lotion for gynaecological imflammation, the lotion is in treatment skin disease, gynaecological imflammation medicine is prepared Using.
The beneficial effects of the invention are as follows:
(1) component is nontoxic " Chinese herbal medicine " kind, safe to use.
(2) prescription is rigorous, and the efficacy of a drug has specific aim, has the antipruritic work(of clearing heat and detoxicating, swelling and pain relieving, desinsection, to eczema There is the effect of good Deng skin disease and gynaecological imflammation etc..
Embodiment
With reference to specific embodiment, the invention will be further described, but does not limit the scope of the invention and apply Scope:
First, the preparation of washing lotion
1. experimental design:
The present invention is prepared into washing lotion respectively with 4 embodiments, and design parameter refers to table 1.
1 washing lotion embodiment preparation parameter table of table
2. operating procedure:
S1:Weigh by weight:Take 20-50 parts of Chinese knotweed, 10-30 parts of smilax, 10-20 parts of grass-leaved sweetflag, iron holly bark 10- 30 parts, 10-30 parts of moutan bark, 10-20 parts of wild chrysanthemum, 10-20 parts of Cortex Phellodendri, clean, it is dry;
S2:Weigh medicinal material total weight percent described in step S1 be the borneol of 0.1-0.3%, medicinal material gross weight described in step S1 Measure the E- polylysines that percentage is 0.2-0.5%;
S3:By load weighted wild chrysanthemum, grass-leaved sweetflag, when adding 6 times of amount water distillating extracting oils 3 small, distillate, medicine are collected Liquid is spare, the dregs of a decoction are incorporated to S4 steps;
S4:Take Chinese knotweed, smilax, iron holly bark, moutan bark, Cortex Phellodendri and wild chrysanthemum and wild chrysanthemum, stone described in step S3 The calamus dregs of a decoction, add 8-15 times of water to decoct 1-3 times, and when each 0.5-3 is small, filtration, merging filtrate, adds the medicine described in step S3 Liquid, is concentrated into thick paste, to obtain the final product;
S5:In the thick paste described in step S4, the distillate described in step S3 is added, stirs evenly, stands overnight, filtered, filter Liquid adds borneol, E- polylysines, stirs evenly, to obtain the final product.
2nd, clinical practice
The present invention is used for the lotion of gynaecological imflammation, is once used to treating and observing 68 patients or volunteer.By above-mentioned preparation 4 kinds of good embodiment samples, are respectively used to following 3 kinds different types of patients or volunteer.
A:(vaginal fluid increases vaginitis, and bean curd slag specimen or curdled milk, there is peculiar smell;Pruritus vulvue, cusalgia are main disease Shape), totally 27, average age 30.2 years old.
B:Vulvitis (skin of vulva itch, pain, burn feeling, urination or when sexual intercourse aggravate cardinal symptom), puts down totally by 26 Equal 31.8 years old age).
C:Eczema (papule, papulo-vesicle or phlysis, substrate flush, itch with skin surface in intensive grain grain size It is acutely cardinal symptom, totally 15, average age 30.8 years old).
The case that each embodiment sample is used for above-mentioned three types is no less than 5.As a result:A groups:Recovery from illness 20, changes It is 6 kind, invalid 1, total effective rate 96.3%;B groups:Recovery from illness 15, improves 11, effective percentage 100%;C groups:Recovery from illness 9, improves 4, Invalid 2, total effective rate 86.7%.The result shows that:The lotion prepared using Chinese medicine composition of the present invention, it is safe to use, effective, There is the effect of good to vaginitis, cervicitis, pelvic infecton, achieve the purpose that to solve patient suffering, effectively improve the quality of life. It is several model cases below:
Case 1:×× is opened, female, 26 years old, hospital diagnosis was vaginitis.Use Chinese medicine composition of the present invention containing Chinese knotweed Manufactured lotion (embodiment 1), 2 times a day, dilutes 30 times of amounts, hip bath and washing vagina with this product, is used in conjunction 5, vaginitis Various symptoms eliminate, recovery from illness.
Case 2:Lee's ××, female, 37 years old, be vulvitis through hospital diagnosis.Using with Chinese medicine group of the present invention containing Chinese knotweed Lotion made of compound (embodiment 2), 2 times a day, dilutes 30 times of amounts, hip bath and washing vagina with this product, is used in conjunction 7, vulva Scorching various symptoms eliminate, recovery from illness.
Case 3:Liu's ××, man, 30 years old, be skin eczema through hospital diagnosis.Using with Chinese medicine of the present invention containing Chinese knotweed Lotion made of composition (embodiment 3), 2 times a day, dilutes 30 times of amounts, each foam washing 20 minutes, is used in conjunction 7, skin with this product The various symptoms of skin eczema eliminate, recovery from illness.
Above content is to combine specific/preferred embodiment further description made for the present invention, it is impossible to Assert that the specific implementation of the present invention is confined to these explanations.Come for general technical staff of the technical field of the invention Say, without departing from the inventive concept of the premise, it can also make some replacements or modification to the embodiment that these have been described, And these are substituted or variant should all be considered as belonging to protection scope of the present invention.

Claims (10)

1. a kind of lotion for gynaecological imflammation, it is characterised in that raw material is made of the traditional Chinese medicinal components of following parts by weight:Chinese knotweed 20-50 parts, 10-30 parts of smilax, 10-20 parts of grass-leaved sweetflag, 10-30 parts of iron holly bark, 10-30 parts of moutan bark, wild chrysanthemum 10-20 Part, 10-20 parts of Cortex Phellodendri;
Its preparation method is:The raw material of above ratio is weighed, then it is 0.1-0.3% to weigh raw material gross weight percentage described above Borneol, raw material gross weight percentage described above be 0.2-0.5% E- polylysines;By load weighted wild chrysanthemum, stone Chang Pu, when adding 6 times of amount water distillating extracting oils 3 small, it is spare to collect distillate, liquid;Take Chinese knotweed, smilax, iron holly bark, male The root bark of tree peony, Cortex Phellodendri and wild chrysanthemum and wild chrysanthemum, the grass-leaved sweetflag dregs of a decoction described in step S3, add water to cook, filter, merging filtrate, then add Enter the liquid described in step S3, be concentrated into thick paste, to obtain the final product;In the thick paste, the distillate is added, stirs evenly, placed Night, filtration, filtrate add borneol, E- polylysines, stir evenly, to obtain the final product.
2. it is used for the lotion of gynaecological imflammation according to claim 1, it is characterised in that the raw material is by following parts by weight Medicine component forms:40 parts of Chinese knotweed, 15 parts of smilax, 15 parts of grass-leaved sweetflag, 20 parts of iron holly bark, 20 parts of moutan bark, 15 parts of wild chrysanthemum, 18 parts of Cortex Phellodendri.
3. it is used for the lotion of gynaecological imflammation according to claim 2, it is characterised in that in the Chinese medicine composition, add Borneol, the E- polylysines of 0.2-0.3% that the Chinese medicine composition total weight percent is 0.2%.
4. it is used for the lotion of gynaecological imflammation according to claim 1, it is characterised in that described " adding water to cook " is addition 8-15 Decoct 1-3 times again.
5. it is used for the lotion of gynaecological imflammation according to claim 4, it is characterised in that the decocting time is each 0.5-3 Hour.
6. a kind of preparation method of the lotion as claimed in claim 1 for gynaecological imflammation, it is characterised in that including following step Suddenly:
S1:Weigh by weight:Take 20-50 parts of Chinese knotweed, 10-30 parts of smilax, 10-20 parts of grass-leaved sweetflag, iron holly bark 10-30 Part, 10-30 parts of moutan bark, 10-20 parts of wild chrysanthemum, 10-20 parts of Cortex Phellodendri, clean, dry;
S2:Weigh medicinal material total weight percent described in step S1 be the borneol of 0.1-0.3%, medicinal material gross weight hundred described in step S1 Divide than the E- polylysines for 0.2-0.5%;
S3:By load weighted wild chrysanthemum, grass-leaved sweetflag, when adding 6 times of amount water distillating extracting oils 3 small, it is standby to collect distillate, liquid S4 steps are incorporated to, the dregs of a decoction;
S4:Take Chinese knotweed, smilax, iron holly bark, moutan bark, Cortex Phellodendri and wild chrysanthemum and wild chrysanthemum, grass-leaved sweetflag described in step S3 The dregs of a decoction, add 8-15 times of water to decoct 1-3 times, and when each 0.5-3 is small, filtration, merging filtrate, adds the liquid described in step S3, It is concentrated into thick paste, to obtain the final product;
S5:In the thick paste described in step S4, the distillate described in step S3 is added, stirs evenly, stands overnight, filtered, filtrate adds Enter borneol, E- polylysines, stir evenly, to obtain the final product.
7. the preparation method of the lotion according to claim 6 for gynaecological imflammation, it is characterised in that the thick paste is 60 DEG C when relative density be 1.25-1.35.
8. the preparation method of the lotion according to claim 6 for gynaecological imflammation, it is characterised in that the step S4 adds Water decocts 2 times.
9. the preparation method of the lotion according to claim 6 for gynaecological imflammation, it is characterised in that the step S4 is decocted Boil the time for 2 it is small when/time.
10. the lotion according to claim 1 for gynaecological imflammation, it is characterised in that the composition is preparing treatment Application in skin disease, gynaecological imflammation medicine.
CN201711479782.1A 2017-12-29 2017-12-29 Lotion for gynaecological imflammation and preparation method thereof Pending CN107929619A (en)

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