CN107929124A - 一种隔离防晒组合物 - Google Patents
一种隔离防晒组合物 Download PDFInfo
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- CN107929124A CN107929124A CN201711243544.0A CN201711243544A CN107929124A CN 107929124 A CN107929124 A CN 107929124A CN 201711243544 A CN201711243544 A CN 201711243544A CN 107929124 A CN107929124 A CN 107929124A
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Abstract
本发明公开了一种隔离防晒组合物，包括紫外线吸收剂、抗氧化剂、镇静舒缓剂的成分，其中，紫外线吸收剂包括白茶提取物、超细纳米钛白粉、纳米氧化锌、水杨酸乙基己酯、丁基甲氧基二苯甲酰基甲烷、芦丁中的一种或以上。组合物中添加紫外线吸收剂能吸收紫外线，减少紫外线对肌肤的损伤，添加抗氧化剂能清除自由基，降低氧化损伤，添加镇静舒缓剂能镇静舒缓肌肤，加强防御紫外线的能力，几种成分配合使用，能起到良好的隔离防晒效果，并将其应用在化妆品中能赋予化妆品显著的隔离防晒作用，更好地保护肌肤。
Description
技术领域
本发明涉及化妆品领域，具体涉及一种隔离防晒组合物。
背景技术
紫外线对人体皮肤有很大的危害，人们口中的“紫外线”实际上还可细分为长波长的UVA，中波长的UVB及短波长的UVC，其中UVC在进入大气层时，已在臭氧层的防护下被隔离，能辐射到地面的只剩UVA和UVB了。UVB只要适当的遮掩即可隔离，它是引起皮肤泛红、发炎及晒伤的主因；UVA会折射进室内，又称为“室内紫外线”，其能深入真皮层，会对胶原、弹力纤维甚至纤维母细胞进行破坏，所以UVA不但是会激发色素合成而使肤色变暗沉，更是造成皮肤老化及细纹产生的主要祸首。皮肤长时间被紫外线照射不仅影响美观，严重时还会造成皮肤癌，因此日常防晒是非常重要的。
现有技术中通过添加紫外吸收剂来吸收紫外线的能量，再以热能或可见光的形式释放出去，从而减少皮肤的伤害，但是很多化学合成紫外吸收剂对皮肤的刺激性大，也有部分透气性差，容易堵塞毛孔，影响汗腺分泌。另外，人们更青睐安全有效，且透气好的产品。
发明内容
本发明的目的在于提供一种隔离防晒组合物，能有效吸收紫外线，并降低氧化损伤，起到良好的隔离防晒效果。
为了达到上述目的，本发明提供如下的技术方案：
一种隔离防晒组合物，包括如下质量份的组分：
紫外线吸收剂 18～35
抗氧化剂 2.5～7.5
镇静舒缓剂 3～8
其中，紫外线吸收剂包括白茶提取物、超细纳米钛白粉、纳米氧化锌、水杨酸乙基己酯、丁基甲氧基二苯甲酰基甲烷、芦丁中的一种或以上。
进一步地，所述的组合物包括如下质量份的组分：
紫外线吸收剂 23.4～32.8
抗氧化剂 3.7～6.4
镇静舒缓剂 4.2～7.3
其中，紫外线吸收剂包括白茶提取物、超细纳米钛白粉、纳米氧化锌、水杨酸乙基己酯、丁基甲氧基二苯甲酰基甲烷、芦丁中的一种或以上。
更进一步地，所述的组合物包括如下质量份的组分：
紫外线吸收剂 28.4
抗氧化剂 5.2
镇静舒缓剂 6.1
其中，紫外线吸收剂包括白茶提取物、超细纳米钛白粉、纳米氧化锌、水杨酸乙基己酯、丁基甲氧基二苯甲酰基甲烷、芦丁中的一种或以上。
另外，所述抗氧化剂包括黄秋葵花提取物、蜂花粉提取物、橙皮提取物中的一种或以上；
所述镇静舒缓剂包括海藻提取物、薄荷醇乳酸酯、金盏花提取液、金缕梅提取液、积雪草提取物中的一种或以上。
本发明所述的组合物可用于化妆品，如可作为添加剂用于防晒类产品，如防晒霜。
与现有技术相比，本分发明具有的有益效果如下：
(1)本发明的组合物中添加紫外线吸收剂能吸收紫外线，减少紫外线对肌肤的损伤，如白茶提取物具有抗辐射的作用，对紫外线照射引发的氧化损伤具有很好的保护作用，芦丁对紫外线具有极强的吸收作用；添加抗氧化剂能清除自由基，降低氧化损伤，如蜂花粉提取物、橙皮提取物能有效发挥抗氧化作用，抑制氧化，阻止因紫外线照射而导致色素沉积；添加镇静舒缓剂能镇静舒缓肌肤，加强防御紫外线的能力；几种成分配合使用，能起到良好的防晒效果；(2)本发明的组合物安全、透气性好，不仅有良好的防晒效果，还能起到一定的隔离作用，将其应用在化妆品中能赋予化妆品显著的隔离防晒作用，更好地保护肌肤。
具体实施方式
以下结合具体实施例对本发明作进一步阐述。
实施例1
隔离防晒组合物的制备：
将28.4克白茶提取物、5.2克蜂花粉提取物、6.1克海藻提取物、60.3克去离子水置于混合器中，搅拌混合均匀，即可得到隔离防晒组合物。
紫外线防护试验：
采用QB/T2410-98《防晒护肤品UVB防晒护肤效果的测定方法—紫外吸光℃法》测定，其相关数据如下表1：
表1
从表1数据可看出实施例1的隔离防晒组合物对紫外线的阻隔率明显高于TiO2、ZnO对紫外线的阻隔率，表明本发明隔离防晒组合物具有优异的抗辐射功效。
抗自由基试验：
一、试验试剂：样品：实施例1所得的隔离防晒组合物a、Vc乙基醚溶液b、去离子水、DPPH(1，1-二甲基苄基苯肼，C18H12O5N6)、无水乙醇。
二、试验方法：
1.准确称取20mg DPPH，用无水乙醇定容于250ml的容量瓶，浓℃为2×104mol/L；
2.取若干试管编号，参照表2添加试剂；
表2：试剂添加量(单位：ml)；
| 组别 | DPPH | 样品 | 去离子水 |
| 空白 | 4.0 | 0 | 2.0 |
| 样品溶液1 | 4.0 | 2.0 | 0 |
| 样品溶液2 | 4.0 | 2.0 | 0 |
3.混合均匀，室温下(25或水浴25)反应10分钟后，测定517nm波长下的吸光℃值。
4.根据下列方式计算清除率：
清除率(％)＝(1-At/A空白)×100％
A空白：空白对照在517nm波长下的吸光℃值；
At：样品在517nm波长下的吸光℃值。
5.以清除DPPH自由基50％的活性物浓℃(RC50)来表征自由基清除剂的功效，抗自由基DPPH自由基活性检测结果见表3。
表3样品抗自由基活性
| 隔离防晒组合物RC50(g/L) | Vc乙基醚溶液RC50(g/L) |
| 0.76 | 0.15 |
三、实验结果：结果表明本发明隔离防晒组合物有较强的清除自由基能力，其活性高于维生素C。
实施例2
隔离霜的制备：
按照质量百分数，将3％甘油硬脂酸酯/PEG-100硬脂酸酯、2％鲸蜡硬脂醇、6％角鲨烷、2.5％聚二甲基硅氧烷、4％辛酸/癸酸甘油三酯、1.2％聚丙烯酰胺、0.1％羟苯甲酯、0.1％羟苯丙酯、10％隔离防晒组合物混合投入油相锅加热搅拌至85℃，搅拌溶解完全，将0.02％透明质酸钠、8％甘油、1.8％生育酚、0.5％卡波姆、55.78％去离子水混合加入水相锅中加热搅拌至85℃，搅拌溶解完全，将乳化锅预热至65℃，搅拌速℃50转/分钟，先将水相抽入，再将油相抽入，搅拌30分钟，温℃保持在85℃，降温至45℃加入5％二氧化钛，保温搅拌10分钟，降温至40℃出料。
实施例3
防晒霜的制备：
按照质量百分数，将4％甘油硬脂酸酯、15％羟基硬脂酸乙基己酯、3％山梨坦油酸酯和15％隔离防晒组合物加热至85℃，搅拌至完全溶解，将7％羟乙基脲、0.4％黄原胶、55％去离子水加热到85℃，搅拌至完全溶解，将油相和水相搅拌混匀，再加入0.4％苯氧乙醇和0.2％香精，搅拌混匀，即得防晒霜。
实施例4
防晒测试：
实验动物：取健康的小鼠25只，体重为18～22g，随机分成5组，每组5只小鼠：一组为空白组(不涂防晒霜和隔离霜)，一组为对比组1(涂抹市售的隔离霜A)，一组为对比组2(涂抹市售的防晒霜B)，两组为实验组(分别涂抹实施例2的隔离霜和实施例3的防晒霜)。
实验方法：各组小鼠用0.8％的硫酸钠进行背部脱毛，暴漏6cm×6cm的测试区。涂抹化妆品之前先用温水清洗皮肤，涂抹有防晒霜、隔离霜的小鼠放在阳光模拟实验箱中1h，连续进行3个月，期间及时剃去新长出的鼠毛。最终，利用皮肤黑色素仪测试受试小鼠皮肤黑色素含量MI值，实验结果，见表4：
表4
| 组别 | 实验前MI值 | 实验后MI值 |
| 空白组 | 162.5±17.6 | 327.6±26.0 |
| 市售的隔离霜A | 160.4±19.2 | 272.7±28.2 |
| 实施例2隔离霜 | 161.8±18.3 | 242.8±19.5 |
| 市售的防晒霜B | 162.7±16.4 | 275.8±26.9 |
| 实施例3防晒霜 | 163.9±13.6 | 240.9±17.3 |
从表4数据可看出市售的隔离霜A、防晒霜B和实施例2隔离霜、实施例3防晒霜均能降低黑色素MI值，而实施例2隔离霜和实施例3防晒霜防晒效果比市售产品更加显著。
以上实施例仅说明本发明的实施方案，并没有对本发明有任何形式上的限制；任何从事本专业的技术人员，都有能力利用揭示的技术内容作出一些更动或修饰，成为等同变化的等效实施例，根据本发明技术实质，对本发明进行简单修改、等同变化与修饰，均属于本发明技术方案的范围内。
Claims (9)
1.一种隔离防晒组合物，其特征在于组分和含量：
紫外线吸收剂 18～35
抗氧化剂 2.5～7.5
镇静舒缓剂 3～8
以上均为质量份；
其中，紫外线吸收剂包括白茶提取物、超细纳米钛白粉、纳米氧化锌、水杨酸乙基己酯、丁基甲氧基二苯甲酰基甲烷、芦丁中的一种或以上。
2.如权利要求1所述的组合物，其特征在于组分和含量：
紫外线吸收剂 23.4～32.8
抗氧化剂 3.7～6.4
镇静舒缓剂 4.2～7.3
以上均为质量份；
其中，紫外线吸收剂包括白茶提取物、超细纳米钛白粉、纳米氧化锌、水杨酸乙基己酯、丁基甲氧基二苯甲酰基甲烷、芦丁中的一种或以上。
3.如权利要求2所述的组合物，其特征在于组分和含量：
紫外线吸收剂 28.4
抗氧化剂 5.2
镇静舒缓剂 6.1
以上均为质量份；
其中，紫外线吸收剂包括白茶提取物、超细纳米钛白粉、纳米氧化锌、水杨酸乙基己酯、丁基甲氧基二苯甲酰基甲烷、芦丁中的一种或以上。
4.如权利要求1所述的组合物，其特征在于：
所述紫外线吸收剂包括白茶提取物、超细纳米钛白粉、纳米氧化锌、水杨酸乙基己酯、丁基甲氧基二苯甲酰基甲烷、芦丁中的一种或以上；
所述抗氧化剂包括黄秋葵花提取物、蜂花粉提取物、橙皮提取物中的一种或以上；
所述镇静舒缓剂包括海藻提取物、薄荷醇乳酸酯、金盏花提取液、金缕梅提取液、积雪草提取物中的一种或以上。
5.如权利要求2所述的组合物，其特征在于：
所述紫外线吸收剂包括白茶提取物、超细纳米钛白粉、纳米氧化锌、水杨酸乙基己酯、丁基甲氧基二苯甲酰基甲烷、芦丁中的一种或以上；
所述抗氧化剂包括黄秋葵花提取物、蜂花粉提取物、橙皮提取物中的一种或以上；
所述镇静舒缓剂包括海藻提取物、薄荷醇乳酸酯、金盏花提取液、金缕梅提取液、积雪草提取物中的一种或以上。
6.如权利要求3所述的组合物，其特征在于：
所述紫外线吸收剂包括白茶提取物、超细纳米钛白粉、纳米氧化锌、水杨酸乙基己酯、丁基甲氧基二苯甲酰基甲烷、芦丁中的一种或以上；
所述抗氧化剂包括黄秋葵花提取物、蜂花粉提取物、橙皮提取物中的一种或以上；
所述镇静舒缓剂包括海藻提取物、薄荷醇乳酸酯、金盏花提取液、金缕梅提取液、积雪草提取物中的一种或以上。
7.如权利要求1～3任一项所述的组合物，其特征在于可用于化妆品。
8.如权利要求1～3任一项所述的组合物，其特征在于可作为添加剂用于防晒类产品。
9.如权利要求1～3任一项所述的组合物，其特征在于可用于防晒霜。
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| CN109010101A (zh) * | 2018-09-17 | 2018-12-18 | 天津大学 | 一种广谱化学防晒剂和广谱防晒霜及其制备方法 |
| CN112245313A (zh) * | 2020-10-19 | 2021-01-22 | 张兴富 | 保湿修复组合物及其制备方法 |
| CN112754947A (zh) * | 2021-01-12 | 2021-05-07 | 上海百雀羚生物科技有限公司 | 一种高效中和无机防晒剂产生自由基的防护体系及其应用 |
| CN117398298A (zh) * | 2023-08-15 | 2024-01-16 | 妆莱(广州)生物研究有限公司 | 薄荷醇衍生物在制备化妆品用舒缓修护增效剂的用途 |
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| CN109010101A (zh) * | 2018-09-17 | 2018-12-18 | 天津大学 | 一种广谱化学防晒剂和广谱防晒霜及其制备方法 |
| CN112245313A (zh) * | 2020-10-19 | 2021-01-22 | 张兴富 | 保湿修复组合物及其制备方法 |
| CN112754947A (zh) * | 2021-01-12 | 2021-05-07 | 上海百雀羚生物科技有限公司 | 一种高效中和无机防晒剂产生自由基的防护体系及其应用 |
| CN117398298A (zh) * | 2023-08-15 | 2024-01-16 | 妆莱(广州)生物研究有限公司 | 薄荷醇衍生物在制备化妆品用舒缓修护增效剂的用途 |
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