CN107920967A - 含有乳胶颗粒和无机金属氧化物的组合物 - Google Patents
含有乳胶颗粒和无机金属氧化物的组合物 Download PDFInfo
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- CN107920967A CN107920967A CN201680045118.3A CN201680045118A CN107920967A CN 107920967 A CN107920967 A CN 107920967A CN 201680045118 A CN201680045118 A CN 201680045118A CN 107920967 A CN107920967 A CN 107920967A
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- methyl
- gap
- unsaturated monomer
- system unsaturated
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Landscapes
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- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US201562202193P | 2015-08-07 | 2015-08-07 | |
| US62/202193 | 2015-08-07 | ||
| US201662366336P | 2016-07-25 | 2016-07-25 | |
| US62/366336 | 2016-07-25 | ||
| PCT/US2016/045321 WO2017027286A1 (en) | 2015-08-07 | 2016-08-03 | Compositions containing voided latex particles and inorganic metal oxides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107920967A true CN107920967A (zh) | 2018-04-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680045118.3A Pending CN107920967A (zh) | 2015-08-07 | 2016-08-03 | 含有乳胶颗粒和无机金属氧化物的组合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20180221254A1 (enExample) |
| EP (1) | EP3331489A1 (enExample) |
| JP (1) | JP6820910B2 (enExample) |
| CN (1) | CN107920967A (enExample) |
| BR (1) | BR112018001974B1 (enExample) |
| WO (1) | WO2017027286A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110958871A (zh) * | 2017-07-28 | 2020-04-03 | 陶氏环球技术有限责任公司 | 用于醇基防晒制剂的spf增效剂 |
| EP3703824A1 (en) | 2017-10-31 | 2020-09-09 | Rohm and Haas Company | Multistage colored polymer particle and skin care formulations comprising same |
| WO2019182714A1 (en) | 2018-03-21 | 2019-09-26 | Dow Global Technologies Llc | Compositions containing latex particles and ir actives |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1148955A (zh) * | 1995-08-24 | 1997-05-07 | 罗姆和哈斯公司 | 改进组合物的紫外线吸收作用的方法 |
| CN1293032A (zh) * | 1999-10-14 | 2001-05-02 | 罗姆和哈斯公司 | 制备紫外线吸收组合物的方法 |
| CN101472551A (zh) * | 2006-06-07 | 2009-07-01 | 宝洁公司 | 抗化色有色微粒以及包含它们的护肤组合物 |
| CN103459580A (zh) * | 2011-03-25 | 2013-12-18 | 蓝宝迪有限公司 | 个人护理组合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1807452B1 (en) * | 2004-11-02 | 2013-05-08 | DSM IP Assets B.V. | Additive for uv-sunscreen preparations |
| FR2918269B1 (fr) * | 2007-07-06 | 2016-11-25 | Oreal | Composition de protection solaire contenant l'association d'un polymere semi-cristallin et de particules de latex creuses. |
| ES2372663T3 (es) * | 2008-12-29 | 2012-01-25 | Rohm And Haas Company | Pinturas de emulsión alquídica extendida de alto brillo. |
| RU2717795C2 (ru) * | 2013-08-22 | 2020-03-25 | Басф Се | Способ получения эмульсионных полимеров |
-
2016
- 2016-08-03 JP JP2018504657A patent/JP6820910B2/ja not_active Expired - Fee Related
- 2016-08-03 EP EP16751436.3A patent/EP3331489A1/en not_active Withdrawn
- 2016-08-03 BR BR112018001974-7A patent/BR112018001974B1/pt not_active IP Right Cessation
- 2016-08-03 CN CN201680045118.3A patent/CN107920967A/zh active Pending
- 2016-08-03 WO PCT/US2016/045321 patent/WO2017027286A1/en not_active Ceased
- 2016-08-03 US US15/749,317 patent/US20180221254A1/en not_active Abandoned
-
2020
- 2020-07-06 US US16/920,789 patent/US20200337951A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1148955A (zh) * | 1995-08-24 | 1997-05-07 | 罗姆和哈斯公司 | 改进组合物的紫外线吸收作用的方法 |
| CN1293032A (zh) * | 1999-10-14 | 2001-05-02 | 罗姆和哈斯公司 | 制备紫外线吸收组合物的方法 |
| CN101472551A (zh) * | 2006-06-07 | 2009-07-01 | 宝洁公司 | 抗化色有色微粒以及包含它们的护肤组合物 |
| CN103459580A (zh) * | 2011-03-25 | 2013-12-18 | 蓝宝迪有限公司 | 个人护理组合物 |
Non-Patent Citations (1)
| Title |
|---|
| 闪中雷: "《把健康带回家—绿色购物指南》", 31 July 2006, 河北科学技术出版社 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018523653A (ja) | 2018-08-23 |
| JP6820910B2 (ja) | 2021-01-27 |
| BR112018001974A2 (pt) | 2018-09-18 |
| EP3331489A1 (en) | 2018-06-13 |
| BR112018001974B1 (pt) | 2021-06-29 |
| US20200337951A1 (en) | 2020-10-29 |
| US20180221254A1 (en) | 2018-08-09 |
| WO2017027286A1 (en) | 2017-02-16 |
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