CN107898988A - A kind of Chinese medicine composition for treating chronic cardiopulmonary disease and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease and preparation method thereof Download PDFInfo
- Publication number
- CN107898988A CN107898988A CN201711302574.4A CN201711302574A CN107898988A CN 107898988 A CN107898988 A CN 107898988A CN 201711302574 A CN201711302574 A CN 201711302574A CN 107898988 A CN107898988 A CN 107898988A
- Authority
- CN
- China
- Prior art keywords
- parts
- medicine composition
- chinese medicine
- radix
- chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 108
- 239000000203 mixture Substances 0.000 title claims abstract description 57
- 201000006306 Cor pulmonale Diseases 0.000 title claims abstract description 45
- 230000001684 chronic effect Effects 0.000 title claims abstract description 40
- 238000002360 preparation method Methods 0.000 title claims abstract description 29
- 235000002722 Dioscorea batatas Nutrition 0.000 claims abstract description 26
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims abstract description 26
- 240000001811 Dioscorea oppositifolia Species 0.000 claims abstract description 26
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims abstract description 26
- 239000009636 Huang Qi Substances 0.000 claims abstract description 26
- 241000237502 Ostreidae Species 0.000 claims abstract description 26
- 235000002789 Panax ginseng Nutrition 0.000 claims abstract description 26
- 244000226566 Psoralea corylifolia Species 0.000 claims abstract description 26
- 235000020636 oyster Nutrition 0.000 claims abstract description 26
- 241000271309 Aquilaria crassna Species 0.000 claims abstract description 24
- 240000006079 Schisandra chinensis Species 0.000 claims abstract description 23
- 235000008422 Schisandra chinensis Nutrition 0.000 claims abstract description 23
- 244000197580 Poria cocos Species 0.000 claims abstract description 22
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 22
- 210000000582 semen Anatomy 0.000 claims abstract description 20
- 239000002994 raw material Substances 0.000 claims abstract description 18
- 229940079593 drug Drugs 0.000 claims abstract description 17
- 238000011282 treatment Methods 0.000 claims description 45
- 241001247821 Ziziphus Species 0.000 claims description 22
- 230000001954 sterilising effect Effects 0.000 claims description 18
- 239000007788 liquid Substances 0.000 claims description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 17
- 239000000843 powder Substances 0.000 claims description 15
- 239000000463 material Substances 0.000 claims description 13
- 238000009835 boiling Methods 0.000 claims description 10
- 239000002775 capsule Substances 0.000 claims description 10
- 239000000706 filtrate Substances 0.000 claims description 10
- 238000007654 immersion Methods 0.000 claims description 10
- 244000068988 Glycine max Species 0.000 claims description 9
- 235000010469 Glycine max Nutrition 0.000 claims description 9
- 239000012535 impurity Substances 0.000 claims description 9
- 238000012216 screening Methods 0.000 claims description 9
- 238000004659 sterilization and disinfection Methods 0.000 claims description 9
- 238000002156 mixing Methods 0.000 claims description 7
- 238000001035 drying Methods 0.000 claims description 5
- 239000002304 perfume Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 24
- 231100000331 toxic Toxicity 0.000 abstract description 9
- 230000002588 toxic effect Effects 0.000 abstract description 9
- 241000721047 Danaus plexippus Species 0.000 abstract description 6
- 244000126002 Ziziphus vulgaris Species 0.000 abstract description 4
- 241000894006 Bacteria Species 0.000 abstract description 3
- 206010059866 Drug resistance Diseases 0.000 abstract description 3
- 210000003462 vein Anatomy 0.000 abstract description 3
- 210000000952 spleen Anatomy 0.000 description 28
- 210000004072 lung Anatomy 0.000 description 25
- 206010011224 Cough Diseases 0.000 description 22
- 208000024891 symptom Diseases 0.000 description 22
- 230000006870 function Effects 0.000 description 21
- 210000003734 kidney Anatomy 0.000 description 21
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 14
- 206010036790 Productive cough Diseases 0.000 description 13
- 201000010099 disease Diseases 0.000 description 13
- 208000000059 Dyspnea Diseases 0.000 description 11
- 206010013975 Dyspnoeas Diseases 0.000 description 11
- 208000004186 Pulmonary Heart Disease Diseases 0.000 description 11
- 210000000038 chest Anatomy 0.000 description 11
- 235000019640 taste Nutrition 0.000 description 11
- 206010062717 Increased upper airway secretion Diseases 0.000 description 10
- 235000009508 confectionery Nutrition 0.000 description 10
- 208000026435 phlegm Diseases 0.000 description 10
- 210000002784 stomach Anatomy 0.000 description 10
- 206010030113 Oedema Diseases 0.000 description 9
- 208000006673 asthma Diseases 0.000 description 9
- 230000007812 deficiency Effects 0.000 description 9
- 238000000034 method Methods 0.000 description 9
- 230000001154 acute effect Effects 0.000 description 8
- 230000008901 benefit Effects 0.000 description 8
- 230000001737 promoting effect Effects 0.000 description 8
- 206010010970 Cor pulmonale chronic Diseases 0.000 description 7
- 206010012735 Diarrhoea Diseases 0.000 description 7
- 208000002193 Pain Diseases 0.000 description 7
- 208000013220 shortness of breath Diseases 0.000 description 7
- 239000008280 blood Substances 0.000 description 6
- 239000000796 flavoring agent Substances 0.000 description 6
- 235000019634 flavors Nutrition 0.000 description 6
- 210000004185 liver Anatomy 0.000 description 6
- 230000002685 pulmonary effect Effects 0.000 description 6
- 238000005728 strengthening Methods 0.000 description 6
- 230000035900 sweating Effects 0.000 description 6
- 230000001225 therapeutic effect Effects 0.000 description 6
- 206010014561 Emphysema Diseases 0.000 description 5
- 206010033557 Palpitations Diseases 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 208000024794 sputum Diseases 0.000 description 5
- 210000003802 sputum Anatomy 0.000 description 5
- 210000002700 urine Anatomy 0.000 description 5
- 238000010792 warming Methods 0.000 description 5
- 206010019280 Heart failures Diseases 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 4
- 208000004880 Polyuria Diseases 0.000 description 4
- 206010047700 Vomiting Diseases 0.000 description 4
- 241001251949 Xanthium sibiricum Species 0.000 description 4
- 230000001914 calming effect Effects 0.000 description 4
- 230000000747 cardiac effect Effects 0.000 description 4
- 230000001976 improved effect Effects 0.000 description 4
- 239000002075 main ingredient Substances 0.000 description 4
- 230000001114 myogenic effect Effects 0.000 description 4
- 208000011580 syndromic disease Diseases 0.000 description 4
- 230000008673 vomiting Effects 0.000 description 4
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 3
- 208000025865 Ulcer Diseases 0.000 description 3
- 210000001015 abdomen Anatomy 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 208000013116 chronic cough Diseases 0.000 description 3
- 230000004087 circulation Effects 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- 201000001881 impotence Diseases 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 206010022437 insomnia Diseases 0.000 description 3
- 230000003902 lesion Effects 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- 230000027939 micturition Effects 0.000 description 3
- 208000002815 pulmonary hypertension Diseases 0.000 description 3
- 230000029058 respiratory gaseous exchange Effects 0.000 description 3
- 230000002269 spontaneous effect Effects 0.000 description 3
- 210000004243 sweat Anatomy 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 231100000397 ulcer Toxicity 0.000 description 3
- 206010000077 Abdominal mass Diseases 0.000 description 2
- 206010008479 Chest Pain Diseases 0.000 description 2
- 206010010904 Convulsion Diseases 0.000 description 2
- 241000699666 Mus <mouse, genus> Species 0.000 description 2
- 206010059013 Nocturnal emission Diseases 0.000 description 2
- 208000012287 Prolapse Diseases 0.000 description 2
- 208000004756 Respiratory Insufficiency Diseases 0.000 description 2
- 206010041349 Somnolence Diseases 0.000 description 2
- 206010046788 Uterine haemorrhage Diseases 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000001142 anti-diarrhea Effects 0.000 description 2
- 210000000436 anus Anatomy 0.000 description 2
- 230000036528 appetite Effects 0.000 description 2
- 235000019789 appetite Nutrition 0.000 description 2
- 206010003119 arrhythmia Diseases 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 230000002612 cardiopulmonary effect Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 208000026636 chronic pulmonary heart disease Diseases 0.000 description 2
- 230000001447 compensatory effect Effects 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 230000001882 diuretic effect Effects 0.000 description 2
- 208000001848 dysentery Diseases 0.000 description 2
- 210000003414 extremity Anatomy 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- 208000019622 heart disease Diseases 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000005906 menstruation Effects 0.000 description 2
- 201000009240 nasopharyngitis Diseases 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 238000000554 physical therapy Methods 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 235000021251 pulses Nutrition 0.000 description 2
- 206010037833 rales Diseases 0.000 description 2
- 201000004193 respiratory failure Diseases 0.000 description 2
- 238000007665 sagging Methods 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 235000019615 sensations Nutrition 0.000 description 2
- 230000002936 tranquilizing effect Effects 0.000 description 2
- 239000011800 void material Substances 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 206010000242 Abortion threatened Diseases 0.000 description 1
- 206010001580 Albuminuria Diseases 0.000 description 1
- 201000000736 Amenorrhea Diseases 0.000 description 1
- 206010001928 Amenorrhoea Diseases 0.000 description 1
- 241000208340 Araliaceae Species 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 description 1
- 206010010969 Cor pulmonale acute Diseases 0.000 description 1
- 206010011703 Cyanosis Diseases 0.000 description 1
- 206010012289 Dementia Diseases 0.000 description 1
- 208000035240 Disease Resistance Diseases 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 206010016952 Food poisoning Diseases 0.000 description 1
- 208000019331 Foodborne disease Diseases 0.000 description 1
- 206010018498 Goitre Diseases 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 208000031361 Hiccup Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010030124 Oedema peripheral Diseases 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 208000037656 Respiratory Sounds Diseases 0.000 description 1
- 208000000924 Right ventricular hypertrophy Diseases 0.000 description 1
- 208000031353 Systolic Murmurs Diseases 0.000 description 1
- 208000005985 Threatened Abortion Diseases 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 206010046274 Upper gastrointestinal haemorrhage Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000001944 accentuation Effects 0.000 description 1
- 201000006303 acute cor pulmonale Diseases 0.000 description 1
- 230000009798 acute exacerbation Effects 0.000 description 1
- 231100000540 amenorrhea Toxicity 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001147 anti-toxic effect Effects 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 230000004872 arterial blood pressure Effects 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 238000002555 auscultation Methods 0.000 description 1
- 230000003542 behavioural effect Effects 0.000 description 1
- 230000007321 biological mechanism Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 206010007625 cardiogenic shock Diseases 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 235000020965 cold beverage Nutrition 0.000 description 1
- 208000012549 congenital acardia Diseases 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 208000009190 disseminated intravascular coagulation Diseases 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 208000017574 dry cough Diseases 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 201000003872 goiter Diseases 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 208000006750 hematuria Diseases 0.000 description 1
- 210000001624 hip Anatomy 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000011221 initial treatment Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000004731 jugular vein Anatomy 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 230000008383 multiple organ dysfunction Effects 0.000 description 1
- 230000004118 muscle contraction Effects 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 206010029410 night sweats Diseases 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 230000000414 obstructive effect Effects 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000003950 pathogenic mechanism Effects 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 210000001147 pulmonary artery Anatomy 0.000 description 1
- 230000004088 pulmonary circulation Effects 0.000 description 1
- 230000036593 pulmonary vascular resistance Effects 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 210000005241 right ventricle Anatomy 0.000 description 1
- 229920002477 rna polymer Polymers 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 210000000591 tricuspid valve Anatomy 0.000 description 1
- 238000002562 urinalysis Methods 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 230000002861 ventricular Effects 0.000 description 1
- 210000002417 xiphoid bone Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/487—Psoralea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/83—Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
- A61K36/835—Aquilaria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of Chinese medicine composition for treating chronic cardiopulmonary disease and preparation method thereof, it is characterised in that the Chinese medicine composition is made of the raw material of following parts by weight：20 30 parts of red ginseng, 10 15 parts of radix astragali, 15 20 parts of Schisandra chinensis, 20 30 parts of keel, 20 30 parts of oyster, 15 20 parts of jujube kernel, 15 20 parts of rhizoma atractylodis macrocephalae, 10 15 parts of Poria cocos, 10 15 parts of Chinese yam, 10 15 parts of rhizoma zingiberis, 10 15 parts of agalloch eaglewood, 15 25 parts of psoralea corylifolia, 10 15 parts of radix cyathulae, 10 15 parts of Semen Cuscutae, 69 parts of radix glycyrrhizae, the present invention is to reinforce vital energy, veins takes off admittedly, the red ginseng of nourishing qi to stop is monarch drug in a prescription；Using radix astragali, Schisandra chinensis as ministerial drug；Using keel, oyster, jujube kernel, rhizoma atractylodis macrocephalae, Poria cocos, Chinese yam, rhizoma zingiberis, agalloch eaglewood, psoralea corylifolia, radix cyathulae, Semen Cuscutae as adjutant；Using radix glycyrrhizae to make medicine.Compatibility is reasonable, has no toxic side effect, and can fundamentally treat chronic cardiopulmonary disease, quick, short treating period, will not cultivate the drug resistance of bacterium, cheap.
Description
Technical field
Patent of the present invention is related to a kind of Chinese medicine, especially a kind of Chinese medicine composition for treating chronic cardiopulmonary disease and its preparation side
Method, belongs to technical field of traditional Chinese medicines.
Background technology
Chronic cor pulmonale (abbreviation pulmonary heart disease) is due to that chronic bronchial, lung, thorax or pulmonary arterial vascular are chronic
Pulmonary vascular resistance increase, pulmonary hypertension caused by lesion and then make Right ventricular hypertrophy, expand, companion or not with right heart function exhaustion
Heart disease.Acute cor pulmonale mainly by main pulmonary artery or the unexpected embolism of its Main Branches, the big portion of pulmonary circulation by
Resistance, so that pulmonary arterial pressure drastically increases, acute right ventricles are expanded and the heart disease of right ventricular function exhaustion.By the compensatory of its function
It is following two that phase carries out division with Decompensated stage：1st, lung, cardiac functional compensatory period (including paracmasis) this phase are mainly chronic resistance
The performance of plug property lung disease (abbreviation chronic obstructive pulmonary disease).Chronic cough, expectoration, out of breath, palpitaition, expiratory dyspnea, weak and labor after activity
Dynamic endurance declines.Physical examination can have obvious pulmonary emphysema to levy, auscultation diminished breath sound, occasionally there is a dry, moist rales, the slight oedema of lower limb,
Afternoon is obvious, and secondary morning disappears.Border of cardiac dullness often is not easy to kowtow out because of pulmonary emphysema.Heart sound is remote, but pulmonary area can have second
The accentuation of cardiac sound, prompts have pulmonary hypertension.There is systolic murmur or xiphoid-process heartbeat shown below in tricuspid valve area, and more promptings have the right side
The heart is plump, expands.Some cases hinder Vena cava return, it is seen that jugular vein fills because pulmonary emphysema raise intrapleural pressure.Again
Because diaphragm declines, the liver upper bound and lower edge is set significantly to move down.2nd, lung, (including Acute Exacerbation Period) current period cardiac functional decompensatory period are clinical
Mainly show based on respiratory failure, with or without heart failure.Since the harm of pulmonary heart disease later stage is bigger, can trigger many concurrent
Disease, at present treatment mainly take doctor trained in Western medicine and physical therapy, take Western medicine for long periods of time and are also easy to produce the drug resistance of germ and are unfavorable for the later stage
Treatment, though physical therapy has body the stimulation of very little, can not be effected a radical cure.
It is immune that studying data at home and abroad confirms no matter aged patients with cor pulmonale exists in acute attack stage or paracmasis
Hypofunction.Due to immunologic hypofunction, prolonged and repeated airway infections, treat successful key and are that timely and effective control is acute
Stage of attack, and control the key of acute attack stage to be infection control, so usually based on antibiosis extract for treating, but antibiotic
Often make bacterial resistance, flora imbalance, side effect is more or killed microorganism destroys, and discharges substantial amounts of ribonucleic acid, makes
Thick sputum is not easy cough and removes, and bacterium constantly breeds, and antibacterial therapy tends not to reach preferable therapeutic effect.Moreover, chronic pulmonary
Worry is common disease, frequently-occurring disease in China, and average illness rate is 0.48%, chronic cardiopulmonary disease in the course of disease often because it is various it is acute simultaneously
Send out disease and go to a doctor and be in hospital repeatedly.The common heart failure of chronic cor pulmonale, pulmonary infection, respiratory failure, lung brain
The complication such as disease and arrhythmia cordis, shock, disseminated intravascular coagulation, upper gastrointestinal bleeding, multiple organ dysfunction.Due to controlling
To treat and be unsatisfied with, chronic cardiopulmonary disease case fatality rate is very high, and average 30% or so.The lung-distension is divided into type of retention of turbid phlegm in the lung, the strongly fragrant lung of phlegm heat by the traditional Chinese medical science
Type, type of water overflowing caused by insuffi ciency of YANG and asthenia of pulmonosplenic qi type, by diagnosis and treatment, treatment of the reasonable formula to pulmonary heart disease is incomparable with doctor trained in Western medicine
Advantage, and toxic side effect is small.So for existing pathomechanism and principle-method-recipe-medicines, need to be further improved understanding, change
Into the Chinese medicine composition with perfect treatment chronic cardiopulmonary disease.
The content of the invention
For the problems of the prior art, the invention aims to provide a kind of Chinese traditional medicine composition for treating chronic cardiopulmonary disease
Thing and preparation method thereof, the Chinese medicine composition prepared by this method is safe and reliable, has no toxic side effect, quick, cheap,
With reference to monarch make up a prescription mechanism carry out compatibility, to chronic cardiopulmonary disease have it is fine the effect of.
In order to achieve the above object, the technical scheme is that：
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease, it is characterised in that the Chinese medicine composition by following parts by weight original
Material composition：20-30 parts of red ginseng, 10-15 parts of radix astragali, 15-20 parts of Schisandra chinensis, 20-30 parts of keel, 20-30 parts of oyster, jujube kernel 15-
20 parts, 15-20 parts of rhizoma atractylodis macrocephalae, 10-15 parts of Poria cocos, 10-15 parts of Chinese yam, 10-15 parts of rhizoma zingiberis, 10-15 parts of agalloch eaglewood, psoralea corylifolia 15-
25 parts, 10-15 parts of radix cyathulae, 10-15 parts of Semen Cuscutae, 6-9 parts of radix glycyrrhizae.
Preferably, which is made of the raw material of following parts by weight：22 parts of red ginseng, 11 parts of radix astragali, the five tastes
16 parts of son, 22 parts of keel, 22 parts of oyster, 16 parts of jujube kernel, 16 parts of rhizoma atractylodis macrocephalae, 11 parts of Poria cocos, 11 parts of Chinese yam, 11 parts of rhizoma zingiberis, agalloch eaglewood
11 parts, 16 parts of psoralea corylifolia, 11 parts of radix cyathulae, 11 parts of Semen Cuscutae, 7 parts of radix glycyrrhizae.
Preferably, which is made of the raw material of following parts by weight：25 parts of red ginseng, 13 parts of radix astragali, the five tastes
27 parts of son, 25 parts of keel, 25 parts of oyster, 17 parts of jujube kernel, 17 parts of rhizoma atractylodis macrocephalae, 13 parts of Poria cocos, 13 parts of Chinese yam, 13 parts of rhizoma zingiberis, agalloch eaglewood
13 parts, 20 parts of psoralea corylifolia, 13 parts of radix cyathulae, 13 parts of Semen Cuscutae, 8 parts of radix glycyrrhizae.
Preferably, which is made of the raw material of following parts by weight：28 parts of red ginseng, 14 parts of radix astragali, the five tastes
18 parts of son, 28 parts of keel, 28 parts of oyster, 18 parts of jujube kernel, 18 parts of rhizoma atractylodis macrocephalae, 14 parts of Poria cocos, 14 parts of Chinese yam, 14 parts of rhizoma zingiberis, agalloch eaglewood
14 parts, 24 parts of psoralea corylifolia, 14 parts of radix cyathulae, 14 parts of Semen Cuscutae, 8 parts of radix glycyrrhizae.
Invention also provides a kind of preparation method of the Chinese medicine composition for the treatment of chronic cardiopulmonary disease as described above, its
It is characterized in that the preparation method includes the following steps：
1), weigh by weight red ginseng, radix astragali, Schisandra chinensis, keel, oyster, jujube kernel, rhizoma atractylodis macrocephalae, Poria cocos, Chinese yam, rhizoma zingiberis,
Agalloch eaglewood, psoralea corylifolia, radix cyathulae, Semen Cuscutae, radix glycyrrhizae, screening removal of impurities, larger raw material are cut into the fritter of soya bean size, are uniformly mixed
When sterilization treatment 1 is small under ultraviolet sterilizing lamp afterwards, it is subsequently placed in container and is soaked 60-100 minutes with normal-temperature water；
2), the Chinese medicine material after immersion and the water of immersion are placed in marmite, after boiling by intense fire, slow boiling heats 30 points
Clock, dries in the air after being down to 50-70 DEG C to temperature, takes filtrate, and the dregs of a decoction in marmite are spare, and filtrate is poured into container；
3), hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then be cooked by slow fire
20 minutes, dry in the air after being down to 50-70 DEG C to temperature, filter to obtain secondary liquid；
4), the liquid obtained in step 2) and step 3) is merged, and is uniformly mixed, bottles or packs after drying in the air to room temperature,
Obtain Traditional Chinese medicine composition liquid medicine.
The above method prepare be for traditional Chinese herbal decoction, the instructions of taking of this traditional Chinese herbal decoction：Take in three times within 1 day.Also can be 1 time
Property decoct the dose of 2 days, filling and sealing after obtained liquid is sterilized, refrigeration, first micro- heating when taking.This Chinese traditional medicine composition
Thing can also be prepared into powder capsule, and concrete scheme is as follows：
The preparation method of the Chinese medicine composition for the treatment of chronic cardiopulmonary disease as described above, it is characterised in that the preparation method bag
Include following steps：
1), weigh by weight red ginseng, radix astragali, Schisandra chinensis, keel, oyster, jujube kernel, rhizoma atractylodis macrocephalae, Poria cocos, Chinese yam, rhizoma zingiberis,
Agalloch eaglewood, psoralea corylifolia, radix cyathulae, Semen Cuscutae, radix glycyrrhizae, screening removal of impurities, larger raw material are cut into the fritter of soya bean size, are uniformly mixed
When sterilization treatment 1 is small under ultraviolet sterilizing lamp afterwards, powder is then ground to, after crossing 500-800 mesh sieves point, obtains herb powder；
2), the herb powder for obtaining step 1), which is fitted into capsule skin, is made Chinese medicinal capsule.
Further, the preparation method 1) granularity of herb powder that obtains in step is 600 mesh.
The Chinese medicine composition of the present invention has no toxic side effect, and therapeutic effect is good, treats both principal and secondary aspect of disease, uneasy to recur, to the chronic pulmonary heart
Disease has good therapeutic effect.
The Chinese medicine composition can be prepared into the diversified forms such as Chinese medicinal tablet, particle, traditional Chinese medicine pill, be not limited to decoction and
Capsule, suitable for a variety of therapeutic modalities, application method.
The pharmacology of all kinds of Chinese medicines is as follows in the present invention：
Red ginseng：Taste：It is sweet, bitter；Property：Temperature；Enter the heart, lung, the spleen channel；Function：Reinforce vital energy, veins takes off admittedly, nourishing qi to stop；It is main
Control：Physically weak to be taken off, cold weak pulse of limb is Qi dysfunction in blood control, metrostaxis；Heart failure, cardiogenic shock.
Radix astragali：It is sweet in flavor；It is warm-natured；Enter spleen, lung channel；Function：Invigorating qi for strengthening superficies, torr sore myogenic, Li Shui；Cure mainly：Deficient qi and blood, from
Sweat, rush down prolapse of the anus for a long time, the prolapse of uterus, ephritis edema, albuminuria, diabetes, chronic ulcer.
Schisandra chinensis：It is sour, sweet；It is warm-natured, return lung, the heart, kidney channel.Function：Astringe the lung, nourshing kidney, promotes the production of body fluid, and receives sweat, puckery essence.Cure mainly：
The deficiency syndrome of the lung is breathed with cough, thirst, spontaneous perspiration, night sweat, and internal lesion caused by overexertion is thin thin, emission, protracted dysentery and diarrhea.
Keel：It is sweet in flavor, puckery, it is mild-natured, enter liver, the heart, kidney channel.Function：Tranquillizing the mind by relieving convulsion, arrest sweating controlling nocturnal emission with astringent drugs, stop blooding puckery intestines, and myogenic is held back
Sore.Cure mainly：Frightened epilepsy is demented, and palpitation is forgetful, insomnia and dreamful sleep, spontaneous sweating, and stranguria with turbid discharge of passing out semen, hematemesis is had blood in stool, and under uterine bleeding band, rush down dysentery takes off
Anus, ulcer do not close up long.
Oyster：Taste：It is salty；Property：It is cold；Enter liver and kidney channel；Function：It is calming the liver；It is transquilization with heavy material；Softening and resolving hard mass；Restrain astringent method；
Cure mainly：Dizziness and tinnitus；Insomnia of palpitating with fear；Scrofula goiter and tumor；Abdominal mass lump in the abdomen；Spontaneous sweating；Seminal emission；Uterine bleeding；Under band.
Jujube kernel：Taste：It is sweet, sour；Property：It is flat；Function：Conscience is nourished, is calmed the nerves, arrest sweating；Cure mainly：Deficiency of YIN-blood, palpitation and severe palpitation, loses
Sleep forgetful；Body void hidrosis.
Rhizoma atractylodis macrocephalae：It is bitter, sweet；It is warm-natured, returns spleen, stomach.Function：Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, tocolysis.Cure mainly：
Spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema.Fetal irritability.
Poria cocos：It is sweet in flavor, light；It is mild-natured；The thoughts of returning home, lung, spleen, kidney channel.Function：Clearing damp and promoting diuresis, invigorating the spleen, calming heart.Cure mainly：Oedema is urinated
It is few, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.
Chinese yam：Taste：It is sweet；Property：It is flat；Enter spleen, lung, kidney channel；Function：Tonifying spleen nourishing the stomach, engender liquid and benefic lung, the puckery essence of kidney tonifying；Cure mainly：Spleen
Void, chronic diarrhea, the deficiency syndrome of the lung, kidney deficiency, with, frequent micturition.
Rhizoma zingiberis：Taste：It is pungent；Property：Heat；Enter spleen, stomach, the heart, lung channel；Function：Warming spleen and stomach for dispelling cold, Back to Yang Tongmai, eliminating dampness dissolving phlegm, warm lung
Change drink.；Cure mainly：Coldness and pain in the epigastrium, vomiting, diarrhea, yang depletion faint inverse, cold drink breath with cough, numbness and ache of cold dampness.
Agalloch eaglewood：Taste：It is pungent, bitter；Property：Temperature；Enter stomach, spleen, kidney channel；Function：Promoting qi circulation and relieving pain, warming middle energizer to arrest vomiting, gas of receiving are relievingd asthma；It is main
Control：Vexed pain that chest and abdomen are swollen, gastrofrigid vomiting hiccup, the asthma of the kidney deficiency circulation of vital energy in the wrong direction are anxious.
Psoralea corylifolia：Acrid flavour, hardship；It is warm-natured；Enter spleen, kidney channel；Function：It is warming spleen and stopping diarrha, tonifying kidney and strengthening yang, astringent sperm contracting urine；Cure mainly：Spleen
The cold of insufficiency type is rushed down, impotence due to deficiency of the kidney, frequent micturition of passing out semen, waist and knee crymodynia.
Radix cyathulae：Taste：It is bitter；Property：It is flat；Enter kidney channel；Function：Wind-dispelling, dampness removing, promoting menstruation, promoting blood circulation；Cure mainly：Amenorrhea abdominal mass, afterbirth
Under not, joint pain, sufficient impotence muscle contraction, cards such as hematuria blood drenches, injury from falling down.
Semen Cuscutae：It is acrid flavour, sweet；It is mild-natured；Enter liver,kidney,spleen warp；Function：Mend Yang and benefiting Yin, astringent sperm contracting urine, improving eyesight, antidiarrheal；It is main
Control：Blood, movement of the foetus are intended to fall under lumbago due to the kidney deficiency, impotence and seminal emission, frequent urination, mesh dark unknown, splenasthenic diarrhea, threatened abortion.
Radix glycyrrhizae：It is sweet in flavor：It is mild-natured.The thoughts of returning home, spleen, lung, stomach.Function：Invigorate the spleen and benefit qi, moisten the lung and relieve the cough, clearing heat and detoxicating, alleviation stops
Bitterly, pharmacological property is relaxed.Cure mainly：Weakness of the spleen and the stomach, shortness of breath and fatigue, palpitation and severe palpitation, cough phlegm is few, pathopyretic ulcer, medicine food poisoning, and gastral cavity abdomen is anxious
Bitterly, four limbs contraction pain.
" organic conception " is had been accepted as at present, " diagnosis and treatment based on an overall analysis of the illness and the patient's condition ", " compound use ", " compound compatibility medication is such as used military forces " are the traditional Chinese medical science
Most scientific most effective several big advantages, wherein " compound compatibility medication is such as used military forces " is the original theory of traditional Chinese medicine of very science.In
The tight compatibility that each medicine is all linked with one another as arraying troops for battle in prescription is cured, is that it is better than the effective means of western medicine formula.The traditional Chinese medical science
Prescription theory thinks that each prescription, not only needs to select the suitable appropriate compatibility of medicine according to etiology and pathogenesis, while should also accord with
Close the prescription compatibility theory of the basic structure of prescription, i.e. " monarch, minister, help, make ", the prescription compatibility of so-called " monarch, minister, help, make ", just
It is that it establishes the scientific matching on the comprehensive judgement basis to the disease interpretation of the cause, onset and process of an illness.Middle medical square is whole by too many levels, Mutiple Targets
The biological mechanism adjusted is closed, therapeutic effect more more longlasting than Western medicine, that more green natural has no toxic side effect can be obtained, and it is this
Curative effect is built upon on the original theoretical accurate instruction of above-mentioned traditional Chinese medical science tradition, and the present invention just have followed this principle.
Monarch drug in a prescription treats primary symptom in the side of referring to, plays the medicine of primary treatment, can use as required simply or a few taste medicines.Minister
Medicine is the medicine assisted main ingredient or strengthen main ingredient effect.Adjutant is the medicine for the toxicity assisted main ingredient treatment and disease or suppress main ingredient
Thing.It is that each medicine of guiding goes directly diseased region or the effect of each medicine of reconciling to make medicine.
The present invention is to reinforce vital energy, and veins takes off admittedly, the red ginseng of nourishing qi to stop is monarch drug in a prescription；With invigorating qi for strengthening superficies, torr sore myogenic, profit
The radix astragali of water, astringe the lung, and nourshing kidney, promotes the production of body fluid, and receives sweat, puckery smart Schisandra chinensis is ministerial drug；With tranquillizing the mind by relieving convulsion, arrest sweating controlling nocturnal emission with astringent drugs, stop blooding puckery intestines,
It is the keel of myogenic sore, calming the liver；It is transquilization with heavy material；Softening and resolving hard mass；Restrain the oyster of astringent method, nourish conscience, calm the nerves, arrest sweating
Jujube kernel, strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, the rhizoma atractylodis macrocephalae of tocolysis, clearing damp and promoting diuresis, invigorating the spleen, the Poria cocos of calming heart, tonifying spleen nourishing the stomach are raw
Tianjin benefit lung, the puckery smart Chinese yam of kidney tonifying, warming spleen and stomach for dispelling cold, Back to Yang Tongmai, eliminating dampness dissolving phlegm, the rhizoma zingiberis of Wenfei of drink, promoting qi circulation and relieving pain, middle benefit gas
Preventing or arresting vomiting, agalloch eaglewood that gas of receiving is relievingd asthma, warming spleen and stopping diarrha, tonifying kidney and strengthening yang, the psoralea corylifolia of astringent sperm contracting urine, wind-dispelling, dampness removing, promoting menstruation, promoting blood circulation
Radix cyathulae, benefit Yang and benefiting Yin, astringent sperm contracting urine, improving eyesight, the Semen Cuscutae of antidiarrheal are adjutant；To invigorate the spleen and benefit qi, moisten the lung and relieve the cough, heat-clearing solution
Poison, alleviates analgesic, and the radix glycyrrhizae for relaxing pharmacological property is to make medicine.Compatibility is reasonable, has no toxic side effect, and can fundamentally treat the chronic pulmonary heart
Disease, quick, short treating period, will not cultivate the drug resistance of bacterium, cheap.
The Chinese medicine composition medicine source broad covered area of the present invention, compatibility is scientific and reasonable, brings out the best in each other, and plays righting altogether and sustains losses in business, is warm
Lung resolving sputum, evacuation fever and chills, the work(of inducing meastruation to relieve menalgia, tonifying spleen and stomach, lesion depths of going directly, to the cause of disease of chronic cor pulmonale into
Row is targetedly put in poison, and has reached the effect of clearing heat and detoxicating, antibacterial anti-inflammatory and resolving sputum and relieving asthma；At the same time, additionally it is possible to nurse one's health people comprehensively
Internal portion function, has the function that tonifying Qi kidney-nourishing, mends fire supporing yang and antitoxic heart-soothing and sedative, enhances the immunity of human body, improve people
The disease resistance of body；Treatment for chronic cardiopulmonary disease has evident in efficacy, quick, cure rate height, efficacy stability, the side of taking
Just, the characteristics of having no toxic side effect.
Embodiment
The present invention is further described with reference to embodiment.
Embodiment one：
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease, it is characterised in that the Chinese medicine by following parts by weight raw material group
Into：30 parts of red ginseng, 15 parts of radix astragali, 20 parts of Schisandra chinensis, 30 parts of keel, 30 parts of oyster, 20 parts of jujube kernel, 20 parts of rhizoma atractylodis macrocephalae, Poria cocos 15
Part, 15 parts of Chinese yam, 15 parts of rhizoma zingiberis, 15 parts of agalloch eaglewood, 25 parts of psoralea corylifolia, 15 parts of radix cyathulae, 15 parts of Semen Cuscutae, 9 parts of radix glycyrrhizae.
The present embodiment also discloses a kind of preparation method of the Chinese medicine composition for the treatment of chronic cardiopulmonary disease as described above,
It is characterized in that the preparation method includes the following steps：
1) 30 parts of red ginseng, 15 parts of radix astragali, 20 parts of Schisandra chinensis, 30 parts of keel, 30 parts of oyster, jujube kernel 20, are weighed by weight
Part, 20 parts of rhizoma atractylodis macrocephalae, 15 parts of Poria cocos, 15 parts of Chinese yam, 15 parts of rhizoma zingiberis, 15 parts of agalloch eaglewood, 25 parts of psoralea corylifolia, 15 parts, Tu of radix cyathulae
Sub 15 parts, 9 parts of radix glycyrrhizae, screening removal of impurities, larger raw material is cut into the fritter of soya bean size, after mixing in ultraviolet sterilizing lamp
When lower sterilization treatment 1 is small, it is subsequently placed in container and is soaked 60 minutes with normal-temperature water；
2), the Chinese medicine material after immersion and the water of immersion are placed in marmite, after boiling by intense fire, slow boiling heats 30 points
Clock, dries in the air after being down to 50 DEG C to temperature, takes filtrate, and the dregs of a decoction in marmite are spare, and filtrate is poured into container；
3), hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then be cooked by slow fire
20 minutes, dry in the air after being down to 50 DEG C to temperature, filter to obtain secondary liquid；
4), the liquid obtained in step 2) and step 3) is merged, and is uniformly mixed, bottles or packs after drying in the air to room temperature,
Obtain Traditional Chinese medicine composition liquid medicine.
Embodiment two
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease, it is characterised in that the Chinese medicine composition by following parts by weight original
Material composition：20 parts of red ginseng, 10 parts of radix astragali, 15 parts of Schisandra chinensis, 20 parts of keel, 20 parts of oyster, 15 parts of jujube kernel, 15 parts of rhizoma atractylodis macrocephalae, Fu
10 parts of Siberian cocklebur, 10 parts of Chinese yam, 10 parts of rhizoma zingiberis, 10 parts of agalloch eaglewood, 15 parts of psoralea corylifolia, 10 parts of radix cyathulae, 10 parts of Semen Cuscutae, 6 parts of radix glycyrrhizae.
The present embodiment provides a kind of preparation method of the Chinese medicine composition for the treatment of chronic cardiopulmonary disease as described above at the same time,
It is characterized in that the preparation method includes the following steps：
1) 20 parts of red ginseng, 10 parts of radix astragali, 15 parts of Schisandra chinensis, 20 parts of keel, 20 parts of oyster, jujube kernel 15, are weighed by weight
Part, 15 parts of rhizoma atractylodis macrocephalae, 10 parts of Poria cocos, 10 parts of Chinese yam, 10 parts of rhizoma zingiberis, 10 parts of agalloch eaglewood, 15 parts of psoralea corylifolia, 10 parts, Tu of radix cyathulae
Sub 10 parts, 6 parts of radix glycyrrhizae, screening removal of impurities, larger raw material is cut into the fritter of soya bean size, after mixing in ultraviolet sterilizing lamp
When lower sterilization treatment 1 is small, powder is then ground to, after crossing 500 mesh sieves point, obtains herb powder；
2), the herb powder for obtaining step 1), which is fitted into capsule skin, is made Chinese medicinal capsule.
Embodiment three：
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease, it is characterised in that the Chinese medicine composition by following parts by weight original
Material composition：22 parts of red ginseng, 11 parts of radix astragali, 16 parts of Schisandra chinensis, 22 parts of keel, 22 parts of oyster, 16 parts of jujube kernel, 16 parts of rhizoma atractylodis macrocephalae, Fu
11 parts of Siberian cocklebur, 11 parts of Chinese yam, 11 parts of rhizoma zingiberis, 11 parts of agalloch eaglewood, 16 parts of psoralea corylifolia, 11 parts of radix cyathulae, 11 parts of Semen Cuscutae, 7 parts of radix glycyrrhizae.
The present embodiment provides a kind of preparation method of the Chinese medicine composition for the treatment of chronic cardiopulmonary disease as described above at the same time,
It is characterized in that the preparation method includes the following steps：
1) 22 parts of red ginseng, 11 parts of radix astragali, 16 parts of Schisandra chinensis, 22 parts of keel, 22 parts of oyster, jujube kernel 16, are weighed by weight
Part, 16 parts of rhizoma atractylodis macrocephalae, 11 parts of Poria cocos, 11 parts of Chinese yam, 11 parts of rhizoma zingiberis, 11 parts of agalloch eaglewood, 16 parts of psoralea corylifolia, 11 parts, Tu of radix cyathulae
Sub 11 parts, 7 parts of radix glycyrrhizae, screening removal of impurities, larger raw material is cut into the fritter of soya bean size, after mixing in ultraviolet sterilizing lamp
When lower sterilization treatment 1 is small, it is subsequently placed in container and is soaked 80 minutes with normal-temperature water；
2), the Chinese medicine material after immersion and the water of immersion are placed in marmite, after boiling by intense fire, slow boiling heats 30 points
Clock, dries in the air after being down to 60 DEG C to temperature, takes filtrate, and the dregs of a decoction in marmite are spare, and filtrate is poured into container；
3), hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then be cooked by slow fire
20 minutes, dry in the air after being down to 60 DEG C to temperature, filter to obtain secondary liquid；
4), the liquid obtained in step 2) and step 3) is merged, and is uniformly mixed, bottles or packs after drying in the air to room temperature,
Obtain Traditional Chinese medicine composition liquid medicine.
Example IV：
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease, it is characterised in that the Chinese medicine composition by following parts by weight original
Material composition：25 parts of red ginseng, 13 parts of radix astragali, 27 parts of Schisandra chinensis, 25 parts of keel, 25 parts of oyster, 17 parts of jujube kernel, 17 parts of rhizoma atractylodis macrocephalae, Fu
13 parts of Siberian cocklebur, 13 parts of Chinese yam, 13 parts of rhizoma zingiberis, 13 parts of agalloch eaglewood, 20 parts of psoralea corylifolia, 13 parts of radix cyathulae, 13 parts of Semen Cuscutae, 8 parts of radix glycyrrhizae.
The present embodiment provides a kind of preparation method of the Chinese medicine composition for the treatment of chronic cardiopulmonary disease as described above at the same time,
It is characterized in that the preparation method includes the following steps：
1) 25 parts of red ginseng, 13 parts of radix astragali, 27 parts of Schisandra chinensis, 25 parts of keel, 25 parts of oyster, jujube kernel 17, are weighed by weight
Part, 17 parts of rhizoma atractylodis macrocephalae, 13 parts of Poria cocos, 13 parts of Chinese yam, 13 parts of rhizoma zingiberis, 13 parts of agalloch eaglewood, 20 parts of psoralea corylifolia, 13 parts, Tu of radix cyathulae
Sub 13 parts, 8 parts of radix glycyrrhizae, screening removal of impurities, larger raw material is cut into the fritter of soya bean size, after mixing in ultraviolet sterilizing lamp
When lower sterilization treatment 1 is small, powder is then ground to, after crossing 600 mesh sieves point, obtains herb powder；
2), the herb powder for obtaining step 1), which is fitted into capsule skin, is made Chinese medicinal capsule.
Embodiment five：
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease, it is characterised in that the Chinese medicine composition by following parts by weight original
Material composition：28 parts of red ginseng, 14 parts of radix astragali, 18 parts of Schisandra chinensis, 28 parts of keel, 28 parts of oyster, 18 parts of jujube kernel, 18 parts of rhizoma atractylodis macrocephalae, Fu
14 parts of Siberian cocklebur, 14 parts of Chinese yam, 14 parts of rhizoma zingiberis, 14 parts of agalloch eaglewood, 24 parts of psoralea corylifolia, 14 parts of radix cyathulae, 14 parts of Semen Cuscutae, 8 parts of radix glycyrrhizae.
The present embodiment provides a kind of preparation method of the Chinese medicine composition for the treatment of chronic cardiopulmonary disease as described above at the same time,
It is characterized in that the preparation method includes the following steps：
1) 28 parts of red ginseng, 14 parts of radix astragali, 18 parts of Schisandra chinensis, 28 parts of keel, 28 parts of oyster, jujube kernel 18, are weighed by weight
Part, 18 parts of rhizoma atractylodis macrocephalae, 14 parts of Poria cocos, 14 parts of Chinese yam, 14 parts of rhizoma zingiberis, 14 parts of agalloch eaglewood, 24 parts of psoralea corylifolia, 14 parts, Tu of radix cyathulae
Sub 14 parts, 8 parts of radix glycyrrhizae, screening removal of impurities, larger raw material is cut into the fritter of soya bean size, after mixing in ultraviolet sterilizing lamp
When lower sterilization treatment 1 is small, it is subsequently placed in container and is soaked 80 minutes with normal-temperature water；
2), the Chinese medicine material after immersion and the water of immersion are placed in marmite, after boiling by intense fire, slow boiling heats 30 points
Clock, dries in the air after being down to 70 DEG C to temperature, takes filtrate, and the dregs of a decoction in marmite are spare, and filtrate is poured into container；
3), hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then be cooked by slow fire
20 minutes, dry in the air after being down to 70 DEG C to temperature, filter to obtain secondary liquid；
4), the liquid obtained in step 2) and step 3) is merged, and is uniformly mixed, bottles or packs after drying in the air to room temperature,
Obtain Traditional Chinese medicine composition liquid medicine.
The present invention has carried out clinical efficacy tracking with the data given by embodiment 1 at the same time, and curative effect is summarized as follows：
1. selecting Patients with Chronic Cor Pulmonale 50, age 35-65 Sui, average age 52 years old, is randomly divided into two groups by patient, controls
There was no significant difference for the data such as treatment group 25, control group 25, two groups of ages, is comparable.Its common classical symptom is
Cough, cough up phlegm, having difficulty in breathing, palpitaition shortness of breath, cyanosis of the lips and nails, abdominal distension oedema, pulmonary rale, tongue nature, tongue fur, pulse condition are abnormal.
2. treatment method, treatment group takes orally Chinese medicine composition made from optimization formula embodiment 1 of the present invention, per bu sooner or later
Take twice, the course for the treatment of 18 days.Control group takes orally general treatment Common drugs, is according to dosage taken daily with number, the course for the treatment of 18 days.
3. diagnostic criteria
All cases meet what State Administration of Traditional Chinese Medicine issued《Chinese medical disease diagnostic criteria》In diagnostic criteria.Ginseng
According to《New Chinese medicine guideline of clinical investigations》Relevant criterion is worked out.
It is effective:Chronic cardiopulmonary disease shape substantially mitigates, and checks that indices tend to be normal, and cardio-pulmonary function, which improves, reaches two level；
Effectively:Property pulmonary heart disease shape slightly mitigate, check indices improved, cardio-pulmonary function improve reaches level-one；
It is invalid:Symptom after taking medicine sign and inspection without improvement or improve unobvious.
4. treatment results, coughed, panted before and after treatment according to patient, the clinical symptoms change situation analysis such as chest is suppressed, edema：
Effective the 75% for the treatment of group, effective 10%, invalid 15%, total effective rate 85%；Effective the 35% of control group, effective 22%, nothing
Effect 43%, total effective rate 57%.
The result shows that Chinese medicine preparation of the invention, can effectively adjust organism quality, there is treatment for treating chronic cardiopulmonary disease
The advantages that definite, cheap, without side-effects, cure rate is high uneasy to recur is imitated, is worth clinical application.
Moreover, in terms of clinical observation result, treatment group's symptom obvious effective rate, total effective rate are obviously higher than control group, it is seen that
The acute phase of cor pulmonale clinical symptoms such as this Chinese medicine preparation is to coughing, panting, chest is suppressed, edema improve obvious.At the same time in safety
Property evaluation in, the inspection such as the front and rear blood routine for the treatment of group patient medication, routine urinalysis, electrocardiogram does not find obvious exception.Thus say
Bright particularly treated using Chinese medicine preparation treatment acute phase of cor pulmonale of the present invention belongs to syndrome of qi deficiency of lung and kidney chronic cardiopulmonary disease urgency
Property the phase it is curative for effect, securely and reliably, can as treatment syndrome of qi deficiency of lung and kidney acute phase of cor pulmonale effective ways, in clinic
It is worth of widely use.
The Chinese medicine of the present invention has carried out toxicity test, and test effect is as follows：
Select 20~22 grams of weight, the healthy mice of 13 week old (homogeneous test body heavy phase difference is no more than 2 grams).Rat 22 weeks
Age；86~96 grams of weight, homogeneous test body heavy phase difference are no more than 10g.During experiment, animal is randomly divided into 4~5 groups by volume,
Every group of at least 10 animals, to reaction of animals situation is observed after tested material at once, once, continuous observation 6 months, sees for observation daily
Examine toxic reaction, should, pays attention to the record appearance of animal, behavioral activity, the state of mind, appetite (feed consumption), stool and urine and
Its color, hair, the colour of skin, breathing, nose, eye, oral cavity secretion without exception, changes of weight etc., compared with control group, administration group is small
White mouse physical condition is normal, and has no that small white mouse is sick or dead.Prompt the medicine security good, have no toxic side effect.
The treatment case of the Chinese medicine of the present invention is as follows：
Case one, Zhao, female, 64 years old.Patient has chronic cough, expectoration medical history more than 10 years, on flu often cause cough,
Expectoration, breaking-out of panting, cough up white foam sample phlegm, when and cough up yellow phlegm, sputum is in mucopurulent sputum, is not easy expectoration, and flu is all every time
Simple is treated with cold symptoms, in winter last year, is occasionally caught a cold, and is repeatedly treated not plus is improved with cold symptoms, disease
Shape aggravates on the contrary, the symptom such as palpitaition, shortness of breath, weak, anorexia, drowsiness, pain uncomfortable in chest occurs, is carried out to the People's Hospital at county level
Checking, outpatient service is in hospital with " chronic obstructive emphysema, pulmonary heart disease " income, is hospitalized for treatment after a week, and above-mentioned symptom does not improve,
When coming here and being treated, purple lips dark purple, edema of lower extremity, expiratory dyspnea, increased heart rate, cardiac arrhythmia, took the present invention after 3 days,
Sensory symptoms has mitigated, and takes the reaction without palpitaition, shortness of breath after a week of the invention, appetite is normal, occurs dry cough once in a while.Afterwards
The symptom such as adhere to no longer occurring after taking one month coughing.Other every Index for examination tend to be normal, and follow-up is without multiple after 1 year
Hair.
Case two, Zhao, man, has checked pulmonary emphysema, in order to for children's schooling, during which take always before 57 years old, 20 years
Western medicine carries out diagnosis and treatment, in recent years, with the increase at age, gradually in addition to cough and expectoration, gradually feel weak, food occur
Be intended to decline, be drowsiness, asthma, uncomfortable in chest, chest pain, last year feels unsmooth breath, nervous, the difficult symptom such as sleep, carried out to county people's hospital
Check, be diagnosed as lang-QI disease, symptom has improved after hospital carries out the treatment of one week, and medication always of going home is treated.
But the state of an illness always hangs in the balance, treated to here, edema disease occur in chest pain, shortness of breath, lower part of the body as pin is pricked when coming
Shape, took the present invention after 5 days, and lower part of the body edema disappears, chest without pain, once in a while on foot when the symptom of shortness of breath occurs, take
After 15 days, the symptom without shortness of breath occurs the present invention, removes examination in hospital, indices tend to be normal.
Case three, Zhang, man, 55 years old, Patients with Chronic Cor Pulmonale, chronic cough, expectoration and different degrees of expiratory dyspnea,
Particularly symptom becomes apparent after activity or in cold season, removes examination in hospital, there is pulmonary hypertension, the increase of the right heart and the right heart
Insufficiency symptom.Take the Chinese medicine composition of the present invention 18 days, cough and expectoration symptom is clearly better, and breathing is no longer difficult, with
After continue to take 35 days, symptom substantially mitigates, and tends to be normal, removes examination in hospital, and indices tend to be normal, then often take
This medicine, expectoration cough, expiratory dyspnea symptom no longer recur.
Case four, position, female, starts to breathe regular relatively difficult before 41 years old, 5 months.Severity uncomfortable in chest, there is kind of an asthma
The but sensation of gas.X pieces have been clapped in local hospital when probably before nearly 1 month, have beaten drop, therapeutic effect unobvious, take
The Chinese medicine composition of the present invention 8 days, hence it is evident that improve, continue thereafter with and take 35 days, symptom substantially mitigates, and tends to be normal, goes to hospital
Check, indices tend to be normal, then often take this medicine, uncomfortable in chest, and asthma shape no longer recurs..
Case five, Lee, man, 65 years old.Cough and asthma, cough symptom, is set to pulmonary heart disease through local hospital x film makings.Add Strong later
Slightly improve after treatment, introduced through friend and eat folk prescription " new asthma is peaceful to be dissipated " always, effect is general, has continuously taken 6-7, has adhered to always
Take.There is sagging sensation in walking Duan Lian Time Hui Chu Now hearts before one month, Xiong Men Time are slightly with hand microtorr chest [close under heart
Portion] there is positive effect, start to take the Chinese medicine composition decoction of the present invention after 15 days, then the sagging sense of acardia, without sense uncomfortable in chest, after
Continuous take 35 days consolidates curative effect, then often takes the Chinese medicine composition of the present invention, pulmonary heart disease symptom is without obvious recurrence.
It is understood that above with respect to the specific descriptions of the present invention, it is merely to illustrate the present invention and is not limited to this
The described technical solution of inventive embodiments, it will be understood by those of ordinary skill in the art that, still the present invention can be carried out
Modification or equivalent substitution, to reach identical technique effect；As long as meet use needs, all protection scope of the present invention it
It is interior.
Claims (7)
- A kind of 1. Chinese medicine composition for treating chronic cardiopulmonary disease, it is characterised in that the Chinese medicine composition by following parts by weight raw material Composition：20-30 parts of red ginseng, 10-15 parts of radix astragali, 15-20 parts of Schisandra chinensis, 20-30 parts of keel, 20-30 parts of oyster, jujube kernel 15-20 Part, 15-20 parts of rhizoma atractylodis macrocephalae, 10-15 parts of Poria cocos, 10-15 parts of Chinese yam, 10-15 parts of rhizoma zingiberis, 10-15 parts of agalloch eaglewood, psoralea corylifolia 15-25 Part, 10-15 parts of radix cyathulae, 10-15 parts of Semen Cuscutae, 6-9 parts of radix glycyrrhizae.
- A kind of 2. Chinese medicine composition for treating chronic cardiopulmonary disease according to claim 1, it is characterised in that the Chinese traditional medicine composition Thing is made of the raw material of following parts by weight：22 parts of red ginseng, 11 parts of radix astragali, 16 parts of Schisandra chinensis, 22 parts of keel, 22 parts of oyster, jujube kernel 16 parts, 16 parts of rhizoma atractylodis macrocephalae, 11 parts of Poria cocos, 11 parts of Chinese yam, 11 parts of rhizoma zingiberis, 11 parts of agalloch eaglewood, 16 parts of psoralea corylifolia, 11 parts of radix cyathulae, Tu Silk 11 parts, 7 parts of radix glycyrrhizae.
- A kind of 3. Chinese medicine composition for treating chronic cardiopulmonary disease according to claim 1, it is characterised in that the Chinese traditional medicine composition Thing is made of the raw material of following parts by weight：25 parts of red ginseng, 13 parts of radix astragali, 27 parts of Schisandra chinensis, 25 parts of keel, 25 parts of oyster, jujube kernel 17 parts, 17 parts of rhizoma atractylodis macrocephalae, 13 parts of Poria cocos, 13 parts of Chinese yam, 13 parts of rhizoma zingiberis, 13 parts of agalloch eaglewood, 20 parts of psoralea corylifolia, 13 parts of radix cyathulae, Tu Silk 13 parts, 8 parts of radix glycyrrhizae.
- A kind of 4. Chinese medicine composition for treating chronic cardiopulmonary disease according to claim 1, it is characterised in that the Chinese traditional medicine composition Thing is made of the raw material of following parts by weight：28 parts of red ginseng, 14 parts of radix astragali, 18 parts of Schisandra chinensis, 28 parts of keel, 28 parts of oyster, jujube kernel 18 parts, 18 parts of rhizoma atractylodis macrocephalae, 14 parts of Poria cocos, 14 parts of Chinese yam, 14 parts of rhizoma zingiberis, 14 parts of agalloch eaglewood, 24 parts of psoralea corylifolia, 14 parts of radix cyathulae, Tu Silk 14 parts, 8 parts of radix glycyrrhizae.
- 5. a kind of preparation method of the Chinese medicine composition for the treatment of chronic cardiopulmonary disease as any one of claim 1-4, its It is characterized in that the preparation method includes the following steps：1) red ginseng, radix astragali, Schisandra chinensis, keel, oyster, jujube kernel, rhizoma atractylodis macrocephalae, Poria cocos, Chinese yam, rhizoma zingiberis, heavy, is weighed by weight Perfume, psoralea corylifolia, radix cyathulae, Semen Cuscutae, radix glycyrrhizae, screening removal of impurities, larger raw material are cut into the fritter of soya bean size, after mixing When sterilization treatment 1 is small under ultraviolet sterilizing lamp, it is subsequently placed in container and is soaked 60-100 minutes with normal-temperature water；2), the Chinese medicine material after immersion and the water of immersion are placed in marmite, after boiling by intense fire, slow boiling heats 30 minutes, dries in the air After being down to 50-70 DEG C to temperature, filtrate is taken, the dregs of a decoction in marmite are spare, and filtrate is poured into container；3), hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then be cooked by slow fire 20 points Clock, dries in the air after being down to 50-70 DEG C to temperature, filters to obtain secondary liquid；4), the liquid obtained in step 2) and step 3) is merged, and is uniformly mixed, bottles or packs after drying in the air to room temperature, in obtaining Drug composition liquid.
- 6. a kind of preparation method of the Chinese medicine composition for the treatment of chronic cardiopulmonary disease as any one of claim 1-4, its It is characterized in that the preparation method includes the following steps：1) red ginseng, radix astragali, Schisandra chinensis, keel, oyster, jujube kernel, rhizoma atractylodis macrocephalae, Poria cocos, Chinese yam, rhizoma zingiberis, heavy, is weighed by weight Perfume, psoralea corylifolia, radix cyathulae, Semen Cuscutae, radix glycyrrhizae, screening removal of impurities, larger raw material are cut into the fritter of soya bean size, after mixing When sterilization treatment 1 is small under ultraviolet sterilizing lamp, powder is then ground to, after crossing 500-800 mesh sieves point, obtains herb powder；2), the herb powder for obtaining step 1), which is fitted into capsule skin, is made Chinese medicinal capsule.
- A kind of 7. preparation method of Chinese medicine composition for treating chronic cardiopulmonary disease according to claim 6, it is characterised in that The preparation method 1) granularity of herb powder that obtains in step is 600 mesh.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711302574.4A CN107898988A (en) | 2017-12-11 | 2017-12-11 | A kind of Chinese medicine composition for treating chronic cardiopulmonary disease and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711302574.4A CN107898988A (en) | 2017-12-11 | 2017-12-11 | A kind of Chinese medicine composition for treating chronic cardiopulmonary disease and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107898988A true CN107898988A (en) | 2018-04-13 |
Family
ID=61865221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711302574.4A Pending CN107898988A (en) | 2017-12-11 | 2017-12-11 | A kind of Chinese medicine composition for treating chronic cardiopulmonary disease and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107898988A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1310003A (en) * | 2001-02-19 | 2001-08-29 | 孟庆云 | Combined Chinese and Western medicine for treating pulmonary emphysema |
-
2017
- 2017-12-11 CN CN201711302574.4A patent/CN107898988A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1310003A (en) * | 2001-02-19 | 2001-08-29 | 孟庆云 | Combined Chinese and Western medicine for treating pulmonary emphysema |
Non-Patent Citations (3)
| Title |
|---|
| 王玲玲: "附子应用体会", 《河南中医》 * |
| 胡俊兴: "中西结合治疗肺心病35例疗效观察", 《中原医刊》 * |
| 鲍丽霞: "中西结合治疗肺心病合并心衰62例临床观察", 《中国社区医师(医学专业)》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102048933B (en) | Chinese medicinal composition for treating infantile diarrhea and preparation method thereof | |
| CN104606513B (en) | A kind of Chinese medicine for treating cardiovascular and cerebrovascular disease and preparation method thereof | |
| CN103405728B (en) | A kind of Chinese medicine composition for the treatment of climacteric syndrome and preparation method thereof | |
| CN102198262A (en) | Chinese medicine preparation for treating infant rotavirus enteritis and preparation method thereof | |
| CN107596197A (en) | A kind of strongly fragrant tea of tonifying Qi solution and preparation method thereof | |
| CN103919008A (en) | Health porridge with spleen and kidney tonifying functions, and preparation method of health porridge | |
| CN104645249B (en) | One kind treats treating coronary heart disease and angina pectoris | |
| CN107898989A (en) | A kind of Chinese medicine composition for treating obstructive sleep apnea syndrome and preparation method thereof | |
| CN104587433B (en) | The plaster tonified the kidney to improve inspiration and its application method of a kind of external application | |
| CN106138785A (en) | One treats neurasthenic Chinese medicine composition and preparation method thereof | |
| CN105831751A (en) | Health-care traditional Chinese medicine composition with effects of tonifying qi and strengthening brain and preparation method and using method thereof | |
| CN107898988A (en) | A kind of Chinese medicine composition for treating chronic cardiopulmonary disease and preparation method thereof | |
| CN105012732B (en) | Traditional Chinese medicine pill for treating sleep disorder syndrome and preparation method thereof | |
| CN107929644A (en) | A kind of Chinese medicine composition for treating sinus bradycardia and preparation method thereof | |
| CN103961578A (en) | Traditional Chinese medicine medicinal liquor for treating neurasthenia | |
| CN107854601A (en) | It is a kind of to treat intractable cough, phlegm, the Chinese medicine composition and preparation method thereof of asthma | |
| CN109464628A (en) | A kind of Chinese medicine composition for treating insomnia | |
| CN107137689A (en) | A kind of Chinese medicine composition for treating menopausal syndrome | |
| CN102793826B (en) | Traditional Chinese medicine for treating hypertension early-stage kidney damage and preparation method thereof | |
| CN105412643A (en) | Spray for treating pediatric water pathogen attacking heart type asthma and preparation method thereof | |
| CN105920574A (en) | Palpitation treatment medicine and preparation method thereof | |
| CN104800546A (en) | Chinese medicinal preparation for treating rheumatic heart disease and preparation method thereof | |
| CN105343629B (en) | A kind of Chinese medicine composition and preparation method thereof for treating cardiac insufficiency | |
| CN104922547A (en) | Traditional Chinese medicine used for treating functional dyspepsia | |
| CN101983698A (en) | Traditional Chinese medicine composition for treating rheumatic heart disease and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180413 |
|
| RJ01 | Rejection of invention patent application after publication |