CN107898721A - A kind of skin matrix and its application - Google Patents
A kind of skin matrix and its application Download PDFInfo
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- CN107898721A CN107898721A CN201711237287.XA CN201711237287A CN107898721A CN 107898721 A CN107898721 A CN 107898721A CN 201711237287 A CN201711237287 A CN 201711237287A CN 107898721 A CN107898721 A CN 107898721A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention belongs to cosmetic technical field, specifically discloses a kind of skin matrix, includes the component of following mass percent：Water 35~55%；Vinasse extract 20~50%；Butanediol 8~15%；Phenoxyethanol 0.3~0.5%；Wild soybean bud extract 0.01~0.1%；The vinasse extract is that vinasse are that 3~7 ︰ 1 mix homogeneous and obtain in mass ratio with water；The Wild soybean is GLYCINE SOJA Wild soybeans.Vinasse extract provided by the invention has stronger moisturizing and oxidation resistance；After vinasse extract is compounded with Wild soybean germ extracts, the anti crease and anti senile old effect of product can be obviously improved, lifts skin-protection product effect；The skin matrix is prepared simple at the same time, and product is easy to get, and can be mass-produced and applies.
Description
Technical field
The invention belongs to cosmetic technical field, more particularly, to a kind of skin matrix and its application.
Background technology
Vinasse are one of main components of Janpanese sake cosmetics, have the effect of notable to U.S. flesh.Vinasse are Japanese liquor brewings
During product.After Janpanese sake is evaporated, make what is formed after adding water, song, yeast microbes.I.e. by rice starch
The ferment sent by Aspergillus, becomes carbohydrate liquid, then becomes Janpanese sake by saccharomycete.After Janpanese sake squeeze and filter,
Residue is exactly vinasse.
Vinasse are rich in various nutrients, such as containing abundant amino acid, vitamin, mineral matter etc., also there is whitening function
Linoleic acid, aspergillic acid, oxidation resistant cinnamic acid.Wherein most important U.S. sarcous element is moisturizing factor NMF（Natural moisturizing factor）
In amino acid.The active ingredient " amino acid " of needed by human body, can synthesized human cell, prevent cell deteriorate or aging, carry
High moisture-retention function of skin, improves the skin problem because of caused by dry skin, skin is recovered elastic water profit.Have in its cutin
Natural moisturizing ingredient, has skin good moisten effect.Amino acid can decomposite ossein, and skin can be made to keep bullet
Property.Another main component of vinasse has Aneurine, B2, and vitamin B group energys make metabolism remain normal.Particularly vitamin
PP, pantothenic acid, folic acid etc.（Including inductor）, often it is applied in cosmetics.And mineral matter, it is natural guarantor for skin
Wet component, can prevent the scytitis because caused by lacking zinc.The organic acids such as lactic acid, citric acid be skin natural moisture preserving into
Point.The high moisturizing ingredient such as amino acid, carbohydrate, in addition, vinasse can also promote the synthesis of lipid ceramide, improves because of neural acyl
The drying flesh of amine reduction, prevents skin problem from producing.
Wild soybean germ extracts, it is quite varied using category, also extremely attract attention in healthy food industry.Due to
It contains the polyamines of high concentration, can effectively prevent saccharification, promotes the hyperplasia of collagen.Wild soybean bud extract can have
Effect promotes the activity of the cell by ultraviolet damage, can also promote the regeneration of collagen being decomposed, and protects old caused by light
Change skin and aged skin caused by the age, can be effectively improved skin it is elastic and obscure the problems such as.
It there are no the product that mentioned component compounds and is used for senile-resistant efficacy at present.
The content of the invention
It is an object of the invention to according to deficiency of the prior art, there is provided a kind of skin matrix.The present invention pass through by
Vinasse extract and Wild soybean germ extracts compounding use, obtain a kind of skin care base with preferable anti crease and anti senile old effect
Matter.
Another object of the present invention is to provide application of the skin matrix in cosmetics are prepared.
Another object of the present invention is to provide a kind of daily eye elite for including the skin matrix.
Another object of the present invention is to provide a kind of face cream for including the skin matrix.
The above-mentioned purpose of the present invention is achieved through the following technical solutions：
A kind of skin matrix, includes the component of following mass percent：
Water 35~55%
Vinasse extract 30~50%
Butanediol 8~15%
Phenoxyethanol 0.3~0.5%
Wild soybean germ extracts 0.01~0.1%
The vinasse extract is that vinasse are that 3~7 ︰ 1 mix homogeneous and obtain in mass ratio with water；The Wild soybean is GLYCINE
SOJA Wild soybeans.
Vinasse extract：The vinasse raw material of the present invention, consolidates for what the brewery from Niigata County, Japan and autumn fields county directly bought
The tabular vinasse of body, Cosmetic Produce Co., Ltd. are made.The qualitative data of vinasse is to refer to japanese food mark
Quasi- component list 2015 editions, core specification is moisture 50%, alcohol（Ethanol）8%.Contain abundant NFM in vinasse extract（It is natural to protect
The wet factor）, have significant moistening effect, can effectively prevent the skin problem because of caused by drying, while new old generation can be promoted
Thank, allow skin to recover gloss.In addition, it can suppress pigment generation rich in ursin and linoleic acid etc. in vinasse, prevent melanin from sinking
Form sediment, prevent color spot.
Wild soybean（GLYCINE SOJA）Germ extracts：Wild soybean germ extracts of the present invention contain highly concentrated
Polyamines is spent, and the amino in polyamines can effectively prevent saccharification, promote the hyperplasia of collagen.This Wild soybean bud extract energy
The activity of the cell by ultraviolet damage is effectively facilitated, can also promote the regeneration of collagen being decomposed, caused by protecting light
Aged skin and aged skin caused by the age, can be effectively improved skin it is elastic and obscure the problems such as.
Vinasse extract and Wild soybean（GLYCINE SOJA）After germ extracts compounding, have the function that anti crease and anti senile old
And moisture-keeping function.Polyamines and the natural moisturizing factor in vinasse extract in Wild soybean germ extracts（NFM）Sent out after compounding
Raw synergistic effect, can be obviously improved the anti crease and anti senile old effect of skin matrix.
In skin matrix of the present invention in addition to the foregoing, while other preservatives, stabilization can also be added
The auxiliary agents such as agent, such as iodine propilolic alcohol butyl mephenesin Carbamate, hydroxypropyl cyclodextrin.
Preferably, the preparation method of the vinasse extract includes the following steps：
S1：Vinasse are crushed, add water stirring and dissolving pulp；The mass ratio of the vinasse and water is 3~7 ︰ 1；
S2：The mixture that step S1 is obtained is sterilized 30~40 minutes at a temperature of 80~90 DEG C, homogeneous, dispersing and filtering extraction
Liquid；Overnight stand obtains vinasse extract.
The present invention extracts vinasse extract at room temperature, at 80 DEG C~90 DEG C, carries out high-temperature sterilizing process, stablizes its product
Matter.And after high-temperature process, the oil-soluble ingredients of dissolution still have at high temperature, easily separate out at low temperature, influence its product
Matter., it is necessary to be filtered, so that can also obtain clear transparent solutions at low temperature when being positioned over room temperature cooling after sterilizing.
Preferably, sterilising temp is 85 DEG C in step S2；Sterilization time is 40min.
Preferably, the Wild soybean germ extracts manufacturer is that company is spun by Japanese Japan, its article number is SPA-
301, the wherein content of active ingredient Wild soybean germ extracts is 5%.The additive amount of Wild soybean germ extracts in skin matrix
It is to be calculated according to the quality of product SPA-301.
Preferably, the skin matrix includes following component by mass percentage：
Water 49.49%
Vinasse extract 40%
Butanediol 10%
Phenoxyethanol 0.5%
Wild soybean germ extracts 0.01%；
The Wild soybean is GLYCINE SOJA Wild soybeans.
The present invention also protects application of the skin matrix in skin care item are prepared at the same time.
Preferably, the skin matrix is added in cosmetics according to 10~20% mass percent.
A kind of daily eye elite, including component by mass percentage as follows：
Component A：15~30% water, 0.1~0.5% acrylic acid（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer, 0.01
~0.05% EDTA-2Na；
B component：5~13% butanediols, 0.2~1% Phenoxyethanol；
Component C：15~22% dipropylene glycols, 2~5% glycerine, 0.1~0.7% Sodium Hyaluronate, 30~45% claims 1 to 6 times
One skin matrix；
D components：1~3% water, 0.02~0.05% potassium hydroxide.
Wherein, the dosage mass ratio of each raw material is for the gross mass of daily eye elite.
A kind of face cream, including component by mass percentage as follows：
Component A：20 ~ 35% water, 0.05~0.1% acrylic acid（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer, 0.01
Any skin matrix of~0.05%EDTA-2Na, 30~40% claims 1 to 6；
B component：4~10% butanediols, 0.3~0.5% Phenoxyethanol, 3~8% glycerine,
Component C：5~10% glycerine three（Thylhexoic acid）Ester, 3~8% vaselines, 1 ~ 2% docosyl alcohol, 0.1~0.5% stearyl alcohol, 2~
5% dimethyl silicone polymer, 1.5~2.5%PEG-60 rilanit specials, 0.5~1.0% PEG-5 stearines；
D components：0.01~0.05% iodine propilolic alcohol butyl mephenesin Carbamate；
Component E：1~3% water, 0.01~0.05% potassium hydroxide.
Compared with prior art, the present invention has the following advantages and beneficial effect：
Vinasse extract provided by the invention has stronger moisturizing and oxidation resistance, and is compounded with Wild soybean germ extracts
Afterwards, the anti crease and anti senile old effect of skin matrix can be obviously improved；The skin matrix, which is added in skin care production, effectively to be lifted
Anti crease and anti senile old effect of skin-protection product.In addition, the preparation process and technique of skin matrix of the present invention are simple, product is easy
, it can be mass-produced and apply.
Embodiment
Further illustrate the present invention below in conjunction with specific embodiment, but embodiment the present invention is not done it is any type of
Limit.Unless stated otherwise, the reagent of the invention used, method and apparatus is the art conventional reagent, methods and apparatus.
Unless stated otherwise, agents useful for same and material of the present invention are purchased in market.
Embodiment 1
A kind of skin matrix, includes the component composition of following mass percent：
Water 49.49%, vinasse extract 40%, butanediol 10%, Phenoxyethanol 0.5%, Wild soybean（GLYCINE SOJA）Plumule carries
Take thing 0.01%.
Wherein vinasse extract is prepared in accordance with the following methods：
S1：Vinasse are crushed, add 80~90 DEG C of ion exchange water, stirring and dissolving pulp；Vinasse and ion exchange water
Mass ratio is（3~7）：1；
S2：Temperature is maintained at 80~90 DEG C, and high-temperature sterilization 40 minutes, in 5000~7000 turns of high speed homogenization, dispersing and filtering carries
Take liquid；Overnight stand is up to vinasse extract.
Embodiment 2
A kind of skin matrix, includes the component composition of following mass percent：
Water 45%, vinasse extract 45%, butanediol 9.49%, Phenoxyethanol 0.5%, Wild soybean（GLYCINE SOJA）Plumule extracts
Thing 0.01%.
Wherein the preparation method of vinasse is the same as embodiment 1.
Embodiment 3
A kind of skin matrix, includes the component composition of following mass percent：
Water 40%, vinasse extract 50%, butanediol 9.5%, Phenoxyethanol 0.4%, Wild soybean（GLYCINE SOJA）Plumule extracts
Thing 0.05%, hydroxypropyl cyclodextrin 0.05%.
Wherein the preparation method of vinasse is the same as embodiment 1.
Embodiment 4
A kind of skin matrix, includes the component composition of following mass percent：
Water 55%, vinasse extract 35%, butanediol 9.5%, Phenoxyethanol 0.4%, Wild soybean（GLYCINE SOJA）Plumule extracts
Thing 0.1%.
Wherein the preparation method of vinasse is the same as embodiment 1.
Comparative example 1
With embodiment 1, difference is to use Sodium Hyaluronate for a kind of skin matrix, its raw material and its dosage and preparation process
1% aqueous solution replaces vinasse extract.
Comparative example 2
With embodiment 1, difference is to use cape jasmine for a kind of skin matrix, its raw material and its dosage and preparation process
（GARDENIA JASMINOIDES）Berry extract replaces Wild soybean（GLYCINE SOJA）Germ extracts.
Comparative example 3
With embodiment 1, difference is that difference is not for a kind of skin matrix, its raw material and its dosage and preparation process
Add Wild soybean（GLYCINE SOJA）Germ extracts.
Comparative example 4
With embodiment 1, difference is adding for vinasse extract for a kind of skin matrix, its raw material and its dosage and preparation process
Dosage is 10%.
Comparative example 5
With embodiment 1, difference is Wild soybean for a kind of skin matrix, its raw material and its dosage and preparation process（GLYCINE
SOJA）The additive amount of germ extracts is 0.002%.
A kind of daily eye elite of application examples one
A kind of daily eye elite, is made of the component of following mass percent：
Component A：20% ion exchange water, 0.3% acrylic acid（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer, 0.05%
EDTA-2Na；
B component：10% butanediol, 0.3% Phenoxyethanol；
Component C：22% dipropylene glycol, 5% glycerine, 0.3% Sodium Hyaluronate, 40% skin matrix；
D components：2% ion exchange water, 0.05% potassium hydroxide.
The preparation method of above-mentioned daily eye elite is as follows：
（1）Sequentially add ion exchange water, the acrylic acid of component A（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer,
EDTA-2Na, stirring and dissolving.
（2）The Phenoxyethanol in component B, add in butanediol, rising temperature for dissolving.
（3）Step（2）Add step（1）In.
（4）Component C is added step again（3）In.Then above-mentioned skin matrix is added.
（5）Potassium hydroxide in component D is slowly added into ion exchange water, stirring and dissolving.
（6）Step（5）Add step（4）In neutralize, confirm dissolved state.
（7）Step（6）Filtered（The filter-cloth filtering of 200 mesh）, after the completion of preserve.
According to the formula and preparation method of above-mentioned daily eye elite, by skin matrix therein according to the skin care base in table 1
Matter is replaced the daily eye elite of 1~9 group of preparation.And by 1~9 group of daily eye elite allow the age between 35-50 one full year of life 60
Name adult female volunteer is tried out in accordance with the following methods：
After every morning face cleaning, after using same toner and lotion, day is used using same gimmick in circumference of eyes
With eye elite.After persistently using 4 weeks and 8 weeks, VISIA-CR is used（Skin of face image analyzer）, measure eye wrinkle-removing situation；
With Biox Aquaflus（Skin water loss analyzer）, test skin water loss degree.
Test result after on probation is shown in Table 1.
Table 1 day eye elite and its application effect
By the data in table 1, the daily eye elite of skin matrix of the present invention is with the addition of after using 12 weeks, eye circumference
The wrinkle decrement that is averaged has been up to 28.34%, average moisture evaporation capacity minimum 10.60%；And in comparative example, eye circumference wrinkle
Average decrement is up to 21.58%, average moisture evaporation capacity minimum 14.65%.It follows that it with the addition of shield of the present invention
The daily eye elite of skin matrix is averaged in eye circumference wrinkle in terms of decrement and average water evaporation quantity, compared with comparative example, is had
More obvious effect.
A kind of two face cream of application examples
A kind of face cream, is made of the component of following mass percent：
Component A：27.03% water, 0.05% acrylic acid（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer, 0.05%
Any skin matrix of EDTA-2Na, 40% claim 1 to 6；
B component：5% butanediol, 0.5% Phenoxyethanol, 3% glycerine；
Component C：8% glycerine three（Thylhexoic acid）Ester, 5% vaseline, 1.8% docosyl alcohol, 0.5% stearyl alcohol, 5% dimethyl silicone polymer,
2% PEG-60 rilanit specials, 1% PEG-5 stearines；
D components：0.05% iodine propilolic alcohol butyl mephenesin Carbamate；
Component E：1% water, 0.02% potassium hydroxide.
A kind of preparation method of above-mentioned face cream is as follows：
（1）Sequentially add ion exchange water, the acrylic acid of component A（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer,
EDTA-2Na, stirring and dissolving, then adds above-mentioned skin matrix, is warming up to 85 DEG C of stirring and dissolvings.
（2）By the part butanediol and Phenoxyethanol stirring and dissolving in B component；Remaining other compositions, are first placed stand-by.
（3）By step（2）The mixture of middle butanediol and Phenoxyethanol adds step（1）In, after stirring and dissolving, add surplus
Under B component.
（4）The glycerine three in component C（Thylhexoic acid）Ester, vaseline, docosyl alcohol, stearyl alcohol, dimethyl silicone polymer,
PEG-60 rilanit specials, PEG-5 stearines, are heated to 85 DEG C of stirring and dissolvings.
（5）Step（4）Add step（3）In, emulsifying, after having confirmed emulsified state, is cooled to 35 DEG C.
（6）D components are added into step（5）In, stirring and dissolving.
（7）Potassium hydroxide in component E is slowly added into ion exchange water, stirring and dissolving.
（8）By step（7）Add step（6）In, confirm dissolved state.
（9）Mixture is finally subjected to filtering and discharging with the filter cloth of 200 mesh.
According to the formula and preparation method of above-mentioned face cream, by skin matrix therein according to the skin matrix in table 2 into
Row, which is replaced, prepares a~i group face cream.And by 60 adult female will of a~i groups face cream by the age between 35-50 one full year of life
Hope person is tried out in accordance with the following methods：
After daily morning and evening face cleaning, after using same toner and after lotion, shield is used using same gimmick in face
Skin frost.After persistently using 4 weeks and 8 weeks, with Biox Aquaflus（Skin water loss analyzer）, test skin average moisture
Evaporation capacity；With the elasticity number of MPA580 measurement facial skins.
Test result such as table 2 after on probation.
2 face cream of table and its application effect
By data in table 2, the face cream of skin matrix of the present invention is with the addition of after using 12 weeks, average moisture is steamed
Hair amount is minimum to have reached 9.60%, and elasticity number has been up to 0.89；And in comparative example, average moisture evaporation capacity is minimum
14.04%, elasticity number is up to 0.76.It follows that the face cream that with the addition of skin matrix of the present invention is steamed in average moisture
In terms of hair amount and elasticity number, compared with comparative example, there is more obvious effect.
To sum up, it was found from from above-mentioned data, skin matrix of the present invention has preferable anti crease and anti senile old effect, addition
After into skin care item, anti crease and anti senile old effect of skin care item can be obviously improved.
The foregoing is only a preferred embodiment of the present invention, is not intended to limit the invention, although with reference to foregoing reality
Apply example the present invention is described in detail, for those skilled in the art, it still can be to foregoing each implementation
Technical solution described in example is modified, or carries out equivalent substitution to which part technical characteristic.All essences in the present invention
With within principle, any modification, equivalent replacement, improvement and so on, should all be included in the protection scope of the present invention god.
Claims (10)
1. a kind of skin matrix, it is characterised in that include the component of following mass percent：
Water 35~55%
Vinasse extract 30 ~ 50%
Butanediol 8~15%
Phenoxyethanol 0.3~0.5%
Wild soybean germ extracts 0.01~0.1%
The vinasse extract is that vinasse are that 3~7 ︰ 1 mix homogeneous and obtain in mass ratio with water；The Wild soybean is GLYCINE
SOJA Wild soybeans.
2. skin matrix according to claim 1, it is characterised in that the preparation method of the vinasse extract includes following step
Suddenly：
S1：Vinasse are crushed, add water stirring and dissolving pulp；The mass ratio of the vinasse and water is 3~7 ︰ 1；
S2：The mixture that step S1 is obtained is sterilized 30~40 minutes at a temperature of 80~90 DEG C, homogeneous, dispersing and filtering extraction
Liquid；Overnight stand obtains vinasse extract.
3. skin matrix according to claim 2, it is characterised in that sterilising temp is 85 DEG C in step S2；Sterilization time is
40min。
4. skin matrix according to claim 2, it is characterised in that the water is ion exchange water.
5. skin matrix according to claim 1, it is characterised in that the manufacturer of the Wild soybean germ extracts is day
Company is spun by this Japan.
6. skin matrix according to claim 1, it is characterised in that including component as follows by mass percentage：
Water 49.49%
Vinasse extract 40%
Butanediol 10%
Phenoxyethanol 0.5%
Wild soybean germ extracts 0.01%；
The Wild soybean is GLYCINE SOJA Wild soybeans.
7. application of any skin matrix of claim 1 to 6 in skin care item are prepared.
8. apply according to claim 7, it is characterised in that in the skin care item quality hundred of skin matrix than for 30~
45%。
9. a kind of daily eye elite, it is characterised in that including component as follows by mass percentage：
Component A：15~30% water, 0.1~0.5% acrylic acid（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer, 0.01
~0.05% EDTA-2Na；
B component：5~13% butanediols, 0.2~1% Phenoxyethanol；
Component C：15~22% dipropylene glycols, 2~5% glycerine, 0.1~0.7% Sodium Hyaluronate, 30~45% claims 1 to 6 times
One skin matrix；
D components：1~3% water, 0.02~0.05% potassium hydroxide.
10. a kind of face cream, it is characterised in that including component as follows by mass percentage：
Component A：20 ~ 35% water, 0.05~0.1% acrylic acid（Ester）Class/C10-30 alkylol acrylamide acid esters cross-linked polymer, 0.01
Any skin matrix of~0.05%EDTA-2Na, 30~40% claims 1 to 6；
B component：4~10% butanediols, 0.3~0.5% Phenoxyethanol, 3~8% glycerine；
Component C：5~10% glycerine three（Thylhexoic acid）Ester, 3~8% vaselines, 1~2% docosyl alcohol, 0.1~0.5% stearyl alcohol, 2~
5% dimethyl silicone polymer, 1.5~2.5% PEG-60 rilanit specials, 0.5~1.0% PEG-5 stearines；
D components：0.01 ~ 0.05% iodine propilolic alcohol butyl mephenesin Carbamate；
Component E：1~3% water, 0.01~0.05% potassium hydroxide.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108478460A (en) * | 2018-05-21 | 2018-09-04 | 杭州千岛湖蓝色天使实业有限公司 | Moisturizing essence cream and preparation method thereof |
| CN110960474A (en) * | 2019-12-27 | 2020-04-07 | 爱思开百朗德生物科技（海门）有限公司 | Anti-inflammatory, antioxidant and anti-wrinkle rice grain essence and preparation method thereof |
| CN111481492A (en) * | 2020-06-12 | 2020-08-04 | 广州鹰远生物科技有限公司 | Composition containing traditional Chinese medicine compound extract and application thereof |
| CN111514084A (en) * | 2020-05-15 | 2020-08-11 | 万京创科(山东)生物科技有限公司 | Rice fermentation product humectant and preparation method and application thereof |
| CN111870566A (en) * | 2020-08-13 | 2020-11-03 | 茅台学院 | Method for extracting composite yeast fermentation product from vinasse and application |
| CN111991326A (en) * | 2020-09-08 | 2020-11-27 | 茅台学院 | Maotai-flavor vinasse extract toning lotion |
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| HSTU-MEI CHIANG等: "Development of Wine Cake as a Skin-Whitening Agent and Humectant", 《JOURNAL OF FOOD AND DRUG ANALYSIS》 * |
| 国家食品药品监督管理总局: "《化妆品安全技术规范》", 31 December 2015 * |
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| CN108478460A (en) * | 2018-05-21 | 2018-09-04 | 杭州千岛湖蓝色天使实业有限公司 | Moisturizing essence cream and preparation method thereof |
| CN110960474A (en) * | 2019-12-27 | 2020-04-07 | 爱思开百朗德生物科技（海门）有限公司 | Anti-inflammatory, antioxidant and anti-wrinkle rice grain essence and preparation method thereof |
| CN111514084A (en) * | 2020-05-15 | 2020-08-11 | 万京创科(山东)生物科技有限公司 | Rice fermentation product humectant and preparation method and application thereof |
| CN111514084B (en) * | 2020-05-15 | 2022-07-01 | 万京创科(广州)生物科技有限公司 | Rice fermentation product humectant and preparation method and application thereof |
| CN111481492A (en) * | 2020-06-12 | 2020-08-04 | 广州鹰远生物科技有限公司 | Composition containing traditional Chinese medicine compound extract and application thereof |
| CN111870566A (en) * | 2020-08-13 | 2020-11-03 | 茅台学院 | Method for extracting composite yeast fermentation product from vinasse and application |
| CN111991326A (en) * | 2020-09-08 | 2020-11-27 | 茅台学院 | Maotai-flavor vinasse extract toning lotion |
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