CN107875075A - A kind of oral care emulsion containing Baical Skullcap root P.E - Google Patents

A kind of oral care emulsion containing Baical Skullcap root P.E Download PDF

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Publication number
CN107875075A
CN107875075A CN201711429881.9A CN201711429881A CN107875075A CN 107875075 A CN107875075 A CN 107875075A CN 201711429881 A CN201711429881 A CN 201711429881A CN 107875075 A CN107875075 A CN 107875075A
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parts
oral care
care emulsion
skullcap root
baical skullcap
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CN201711429881.9A
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谭新华
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Priority to CN201711429881.9A priority Critical patent/CN107875075A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/28Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/413Nanosized, i.e. having sizes below 100 nm

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)

Abstract

A kind of oral care emulsion containing Baical Skullcap root P.E, it includes following components in parts by weight:3.0~4.5 parts of acrylic acid polymer;1.0~3.0 parts of sodium lauroyl sarcosine;28~40 parts of NMF;0.2~0.5 part of sweetener;0.3~0.7 part of thickener;30~50 parts of rubbing agent;10~25 parts of deionized water;2~4 parts of Baical Skullcap root P.E, 0.1~0.5 part of licorice, 0.1~0.3 part of Rhizoma Polygonati Odorati extract, 0.1~0.3 part of Ginger P.E;The rubbing agent is wolf's milk powder.The present invention uses wolf's milk powder both effectively to drive away tooth stain as the rubbing agent of oral care emulsion, and and can avoids therefore friction causes the phenomenon of bleeding gums, and need not add new hemostatic compositions, so as to reduce the production cost of oral care emulsion.

Description

A kind of oral care emulsion containing Baical Skullcap root P.E
Technical field
The present invention relates to a kind of commodity technical field, more particularly to a kind of oral care emulsion containing Baical Skullcap root P.E.
Background technology
Periodontal disease is common mouth disease, and its symptom mainly has bleeding gums, swelling, pain.There is statistics to show, tooth The main reason for all diseases are more than 35 years old crowd's absence of tooth, it is seen that the seriousness of periodontal disease.But because patient is not easy to examine Feel, most people is not aware that oneself is suffered from this disease.Think that people can just suffer from periodontal disease to old many human factor errors, it is actual Upper 5 year old, children's can suffered from gingivitis.
Periodontosis is not only to influence the health of tooth, can also systemic health.Periodontosis is to whole body health in recent years Influence caused the concern of people.Bacterial component and bacterial product are easy to be diffused into by oral pocket ulcer surface nearby or remote Every organ, cause or aggravate some general diseases, such as coronary heart disease, low birth weight infant, diabetes, the hair of pulmonary infection disease Hair tonic exhibition, seriously endanger health.It is that can not meet that people improve oral health water to depend merely on stomatological hospital and drug therapy Flat needs, with the use of the oral cavity nursing health products with preventing and treating periodontal disease, periodontal disease is that progressively to be had Imitate what is prevented and control.
In order to preferably prevent and treat periodontal disease, many people's selections are added into rubbing agent in toothpaste, but are added into friction After agent, people have found the easy bleeding of gum when carrying out oral care using the toothpaste with rubbing agent, so as to easily cause sense Dye, and in order to stop blooding, also also need to be added into hemostatic compositions in toothpaste, must can so increase the production of oral care emulsion Cost.
The content of the invention
It is an object of the invention to overcome the shortcomings of that the above and defect propose a kind of oral care breast containing Baical Skullcap root P.E Liquid.
To use following technical scheme up to this purpose, the present invention:
A kind of oral care emulsion containing Baical Skullcap root P.E, it includes following components in parts by weight:
3.0~4.5 parts of acrylic acid polymer;
1.0~3.0 parts of sodium lauroyl sarcosine
28~40 parts of NMF;
0.2~0.5 part of sweetener;
0.3~0.7 part of thickener;
15~30 parts of rubbing agent;
10~25 parts of deionized water;
2~4 parts of Baical Skullcap root P.E;
0.1~0.5 part of licorice;
0.1~0.3 part of Rhizoma Polygonati Odorati extract;
0.1~0.3 part of Ginger P.E;
The rubbing agent is wolf's milk powder.
Preferably, it also includes 0.02-0.06 part preservatives.
Preferably, the preservative is more than one or both of OIT, nipagin esters, potassium sorbate mixed Compound.
Preferably, the NMF compounds for the one or more of which of propane diols, butanediol or glycine betaine.
Preferably, the sweetener is the one or two of saccharin sodium or xylitol.
Preferably, the thickener is that sodium carboxymethylcellulose, hydroxyethyl cellulose, the one or more of carbomer are answered Match somebody with somebody.
Preferably, the size of wolf's milk powder is 500-1000 mesh.If the powder used crosses expense when conference causes to brush teeth Power, cause the inconvenience brushed teeth;If too small, easily remained in the space of tooth in friction process, friction is reduced, so as to drop The ability that low tooth stain is driven away.And wolf's milk floury texture is not hard, injury of teeth will not be caused.
The present invention is used as rubbing agent by adding wolf's milk powder in oral care emulsion, makes the oral care of acquisition Emulsion can quickly remove the dirt for being attached to dental surface, tooth jaundice or long decayed tooth be avoided, simultaneously because the effect of friction, tooth The easy bleeding of gum, and humid euphorbia grass meal has the effect of cooling blood and hemostasis in itself, therefore use in wolf's milk powder as rubbing agent Oral care emulsion both effectively drives away tooth stain, and and can enough avoids therefore rubbed to cause the phenomenon of bleeding gums, and need not New hemostatic compositions are added, so as to reduce the production cost of oral care emulsion.
Embodiment
Technical scheme is further illustrated below by embodiment.
Embodiment 1
A kind of oral care emulsion containing Baical Skullcap root P.E, it includes following components in parts by weight:
3.0 parts of acrylic acid polymer;
1.0 parts of sodium lauroyl sarcosine;
28 parts of glycine betaine;
0.2 part of saccharin sodium;
0.3 part of sodium carboxymethylcellulose;
Wolf's milk powder:Addition is added by table 1;
0.02 part of nipagin esters;
10 parts of deionized water;
2 parts of Baical Skullcap root P.E;
0.1 part of licorice;
0.1 part of Rhizoma Polygonati Odorati extract;
0.2 part of Ginger P.E.
Table 1 is influence of the addition of rubbing agent to expeling tooth stain ability
It can be obtained by table 1, rubbing agent of the wolf's milk powder as toothpaste, the ability for driving away tooth stain enhances, and not Pipe is that the expeling dirt ability of the tooth stain for being aged 15 days or 30 days can reach more than 91, and optimal expeling is dirty It using 28 parts of wolf's milk powder as the ability of the expeling tooth stain of the toothpaste of rubbing agent is most strong that dirty effect, which is,.
In order to test the effect of the present embodiment 1-1 to embodiment 1-3 obtains the hemostasis aspect of oral care emulsion, carry out small The clinical hemostasis experiment of the clinical hemostasis experiment mice of mouse.
Clinical trial of stopping blooding uses blank lotion, black younger sister's toothpaste, lengsuanling toothpaste, embodiment 1-1 into embodiment 1-3 Oral care emulsion is as examination thing sample.
Carried out using hemostasis observational technique is damaged to mouse liver local woanded surface.Take the kunming mice 108 of health, body weight 18~22g, male and female dual-purpose.After anesthetized mice, cut liver in left lobe of liver with operating scissors and be about 0.5cm, wide about 0.5cm, it is high about 0.5cm, after the blood for wiping ejection, immediately in situation portion spreading thing sample 0.5g to be tried, 1min is oppressed with 200g counterweights, after 1min Counterweight is removed, haemostatic effect is observed, untill not bleeding.Such as still bleeding, add to apply and pressurizeed after thing sample is tried, observed every 30s Once, bleeding stopping period is recorded, is such as no more than 3min, is then designated as stopping blooding;Such as fail to stop blooding more than 3min, be then designated as failing to stop Blood, experimental result are shown in Table 2.
The clinical blood coagulation hemostasis experimental result of the mouse of table 2
Try thing sample Experiment number Bleeding stopping period
Blank lotion 18 > 3
Black younger sister's toothpaste 18 2.70±0.22
Lengsuanling toothpaste 18 2.58±0.18
Embodiment 1-1 oral care emulsion 18 2.32±0.15
Embodiment 1-2 oral care emulsion 18 2.18±0.13
Embodiment 1-3 oral care emulsion 18 2.10±0.12
As shown in Table 2, embodiment 1-1 to embodiment 1-3 oral care emulsion is damaged out to mouse liver local woanded surface Blood has obvious blood coagulation haemostatic effect.
Embodiment 2
A kind of oral care emulsion containing Baical Skullcap root P.E, it includes following components in parts by weight:
4.5 parts of acrylic acid polymer;
3.0 parts of sodium lauroyl sarcosine;
30 parts of butanediol;
0.3 part of saccharin sodium;
0.7 part of hydroxyethyl cellulose;
Wolf's milk powder:17 parts;
0.06 part of potassium sorbate;
20 parts of deionized water;
4 parts of Baical Skullcap root P.E;
0.4 part of licorice;
0.25 part of Rhizoma Polygonati Odorati extract;
0.3 part of Ginger P.E.
The oral care emulsion of the present embodiment is 96/12 day for the expeling ability of the tooth stain of ageing 15 days;For The expeling ability of the tooth stain of ageing 30 days is 91/16 day.
Embodiment 3
A kind of oral care emulsion containing Baical Skullcap root P.E, it includes following components in parts by weight:
3.5 parts of acrylic acid polymer;
2.0 parts of sodium lauroyl sarcosine;
32 parts of propane diols;
0.5 part of xylitol;
0.6 part of carbomer;
Wolf's milk powder:23.5 parts;
0.04 part of OIT;
15.5 parts of deionized water;
3 parts of Baical Skullcap root P.E;
0.5 part of licorice;
0.3 part of Rhizoma Polygonati Odorati extract;
0.15 part of Ginger P.E.
The oral care emulsion of the present embodiment is 97/10 day for the expeling ability of the tooth stain of ageing 15 days;For The expeling ability of the tooth stain of ageing 30 days is 92/13 day.
Embodiment 4
A kind of oral care emulsion containing Baical Skullcap root P.E, it includes following components in parts by weight:
4 parts of acrylic acid polymer;
3.2 parts of sodium lauroyl sarcosine;
35 parts of glycine betaine;
0.3 part of saccharin sodium;
0.2 part of sodium carboxymethylcellulose, 0.2 part of hydroxyethyl cellulose, 0.3 part of carbomer;
19.5 parts of wolf's milk powder;
Nipagin esters 0.25,0.15 part of potassium sorbate;
22 parts of deionized water;
2.5 parts of Baical Skullcap root P.E;
3.5 parts of licorice;
0.15 part of Rhizoma Polygonati Odorati extract;
0.3 part of Ginger P.E.
The oral care emulsion of the present embodiment is 96/11 day for the expeling ability of the tooth stain of ageing 15 days;For The expeling ability of the tooth stain of ageing 30 days is 92/15 day.
Embodiment 5
A kind of oral care emulsion containing Baical Skullcap root P.E, it includes following components in parts by weight:
4.5 parts of acrylic acid polymer;
2.5 parts of sodium lauroyl sarcosine;
30 parts of butanediol;
0.4 part of xylitol;
0.4 part of sodium carboxymethylcellulose, 0.2 part of hydroxyethyl cellulose;
27 parts of wolf's milk powder,
0.02 part of OIT, 0.03 part of nipagin esters;
14 parts of deionized water;
3.5 parts of Baical Skullcap root P.E;
0.3 part of licorice;
0.2 part of Rhizoma Polygonati Odorati extract;
0.2 part of Ginger P.E.
The oral care emulsion of the present embodiment is 98/11 day for the expeling ability of the tooth stain of ageing 15 days;For The expeling ability of the tooth stain of ageing 30 days is 93/13 day.
Embodiment 6
A kind of oral care emulsion containing Baical Skullcap root P.E, it includes following components in parts by weight:
3.5 parts of acrylic acid polymer;
2.1 parts of sodium lauroyl sarcosine;
38 parts of propane diols;
0.3 part of xylitol, 0.2 part of saccharin sodium;
0.1 part of sodium carboxymethylcellulose, 0.3 part of carbomer;
Wolf's milk powder:20.5 parts;
0.05 part of OIT;
17.5 parts of deionized water;
2.8 parts of Baical Skullcap root P.E;
0.3 part of licorice;
0.25 part of Rhizoma Polygonati Odorati extract;
0.1 part of Ginger P.E.
The oral care emulsion of the present embodiment is 97/12 day for the expeling ability of the tooth stain of ageing 15 days;For The expeling ability of the tooth stain of ageing 30 days is 92/14 day.
Embodiment 7
A kind of oral care emulsion containing Baical Skullcap root P.E, it includes following components in parts by weight:
4.1 parts of acrylic acid polymer;
2.7 parts of sodium lauroyl sarcosine;
10 parts of propane diols, 21 parts of glycine betaine;
0.3 part of saccharin sodium;
0.25 part of hydroxyethyl cellulose, 0.35 part of carbomer;
26.5 parts of wolf's milk powder;
0.01 part of OIT, 0.01 part of potassium sorbate;
14.5 parts of deionized water;
3.5 parts of Baical Skullcap root P.E;
0.5 part of licorice;
0.3 part of Rhizoma Polygonati Odorati extract;
0.3 part of Ginger P.E.
The oral care emulsion of the present embodiment is 98/12 day for the expeling ability of the tooth stain of ageing 15 days;For The expeling ability of the tooth stain of ageing 30 days is 92/13 day.
Embodiment 8
A kind of oral care emulsion containing Baical Skullcap root P.E, it includes following components in parts by weight:
3.8 parts of acrylic acid polymer;
2.5 parts of sodium lauroyl sarcosine;
24 parts of butanediol, 10 parts of glycine betaine;
0.3 part of xylitol, 0.1 part of saccharin sodium;
0.55 part of hydroxyethyl cellulose;
Wolf's milk powder:24 parts;
0.01 part of OIT, 0.02 part of nipagin esters;
20.5 parts of deionized water;
3.2 parts of Baical Skullcap root P.E;
0.45 part of licorice;
0.2 part of Rhizoma Polygonati Odorati extract;
0.25 part of Ginger P.E.
The oral care emulsion of the present embodiment is 98/12 day for the expeling ability of the tooth stain of ageing 15 days;For The expeling ability of the tooth stain of ageing 30 days is 93/15 day.
Embodiment 9
A kind of oral care emulsion containing Baical Skullcap root P.E, it includes following components in parts by weight:
3.2 parts of acrylic acid polymer;
1.2 parts of sodium lauroyl sarcosine;
28 parts of propane diols, butanediol or glycine betaine;
0.25 part of xylitol;
0.35 part of sodium carboxymethylcellulose;
18.5 parts of wolf's milk powder;
0.02 part of OIT, 0.01 part of nipagin esters, 0.03 part of potassium sorbate;
15 parts of deionized water;
1.2 parts of Baical Skullcap root P.E;
2.8 parts of licorice;
1.7 parts of Rhizoma Polygonati Odorati extract;
2.8 parts of Ginger P.E.
The oral care emulsion of the present embodiment is 96/10 day for the expeling ability of the tooth stain of ageing 15 days;For The expeling ability of the tooth stain of ageing 30 days is 91/16 day.
Embodiment 10
A kind of oral care emulsion containing Baical Skullcap root P.E, it includes following components in parts by weight:
3.6 parts of acrylic acid polymer;
1.8 parts of sodium lauroyl sarcosine;
14 parts of propane diols, 23 parts of butanediol;
0.2 part of xylitol, 0.25 part of saccharin sodium;
0.5 part of carbomer;
Wolf's milk powder:29 parts;
0.01 part of potassium sorbate, 0.02 part of OIT;
25 parts of deionized water;
4 parts of Baical Skullcap root P.E;
0.25 part of licorice;
2.2 parts of Rhizoma Polygonati Odorati extract;
2.7 parts of Ginger P.E.
The oral care emulsion of the present embodiment is 97/10 day for the expeling ability of the tooth stain of ageing 15 days;For The expeling ability of the tooth stain of ageing 30 days is 93/12 day.
The technical principle of the present invention is described above in association with specific embodiment.These descriptions are intended merely to explain the present invention's Principle, and limiting the scope of the invention can not be construed in any way.Based on explanation herein, the technology of this area Personnel would not require any inventive effort the other embodiments that can associate the present invention, and these modes are fallen within Within protection scope of the present invention.

Claims (7)

1. a kind of oral care emulsion containing Baical Skullcap root P.E, it is characterised in that it includes following components in parts by weight:
3.0~4.5 parts of acrylic acid polymer;
1.0~3.0 parts of sodium lauroyl sarcosine
28~40 parts of NMF;
0.2~0.5 part of sweetener;
0.3~0.7 part of thickener;
30~50 parts of rubbing agent;
10~25 parts of deionized water;
2~4 parts of Baical Skullcap root P.E;
0.1~0.5 part of licorice;
0.1~0.3 part of Rhizoma Polygonati Odorati extract;
0.1~0.3 part of Ginger P.E;
The rubbing agent is wolf's milk powder.
A kind of 2. oral care emulsion containing Baical Skullcap root P.E according to claim 1, it is characterised in that:It also includes 0.02-0.06 part preservatives.
A kind of 3. oral care emulsion containing Baical Skullcap root P.E according to claim 2, it is characterised in that:The preservative For mixture more than one or both of OIT, nipagin esters, potassium sorbate.
A kind of 4. oral care emulsion containing Baical Skullcap root P.E according to claim 1, it is characterised in that:The NMF Compounded for the one or more of which of propane diols, butanediol or glycine betaine.
A kind of 5. oral care emulsion containing Baical Skullcap root P.E according to claim 1, it is characterised in that:The sweetener For the one or two of saccharin sodium or xylitol.
A kind of 6. oral care emulsion containing Baical Skullcap root P.E according to claim 1, it is characterised in that:The thickener Compounded for sodium carboxymethylcellulose, hydroxyethyl cellulose, the one or more of carbomer.
A kind of 7. oral care emulsion containing Baical Skullcap root P.E according to claim 1, it is characterised in that:The wolf's milk The size of powder is 500-1000 mesh.
CN201711429881.9A 2017-12-26 2017-12-26 A kind of oral care emulsion containing Baical Skullcap root P.E Withdrawn CN107875075A (en)

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CN201711429881.9A CN107875075A (en) 2017-12-26 2017-12-26 A kind of oral care emulsion containing Baical Skullcap root P.E

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Application Number Priority Date Filing Date Title
CN201711429881.9A CN107875075A (en) 2017-12-26 2017-12-26 A kind of oral care emulsion containing Baical Skullcap root P.E

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104248571A (en) * 2014-09-19 2014-12-31 云南七丹药业股份有限公司 Purely natural plant-containing abradant toothpaste and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104248571A (en) * 2014-09-19 2014-12-31 云南七丹药业股份有限公司 Purely natural plant-containing abradant toothpaste and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
老中医养生堂: "《本草纲目中药草使用图鉴》", 30 April 2016, 福建科学技术出版社 *

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Application publication date: 20180406