CN107854366A - A kind of preparation method of natural fruit pigment used for cosmetic - Google Patents
A kind of preparation method of natural fruit pigment used for cosmetic Download PDFInfo
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- CN107854366A CN107854366A CN201711357450.6A CN201711357450A CN107854366A CN 107854366 A CN107854366 A CN 107854366A CN 201711357450 A CN201711357450 A CN 201711357450A CN 107854366 A CN107854366 A CN 107854366A
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- fruit
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
- A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
- A61Q1/06—Lipsticks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/001—Preparations for care of the lips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q3/00—Manicure or pedicure preparations
- A61Q3/02—Nail coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of preparation method of natural fruit pigment used for cosmetic, it is related to beauty makeups technical field.The present invention significantly increases the efficiency from fruit extraction natural pigment using microwave ultrasonic wave auxiliary extraction technology first, then prohibits characteristic to the protein in fruit pigment extract and macromolecular substances removing impurity by means of precipitation using the limit of supermolecule solvent；Finally using eutectic reagent aqueous two-phase extraction except pigment is further purified the highly polar material of fruit pigment extract kind, natural high-purity fruit pigment is obtained.The natural pigment obtained through the present invention can be directly used in the cosmetics such as lipstick, profit lip night, lip gloss, lipblock, nail polish.
Description
Technical field
The present invention relates to beauty makeups technical field, specially a kind of preparation side of natural fruit pigment used for cosmetic
Method.
Background technology
The use of today's society cosmetics is very universal, color make-up product as most by women welcome cosmetics species it
One, in order to reach increase Natural color, prominent face feature and other effects, often add a certain amount of pigment.At present, a variety of cosmetics
Product are all to be made by " color lake " colouring agent to make water soluble fuel be converted into not lysochrome with pigment, and this pigment contains a huge sum of money
Belong to material, long-term use can cause skin injury, so as to unhealthful.Therefore developing green and healthy natural pigment pigment has
Important meaning.
The A of patent CN 102399452《A kind of extracting process of grape skin color》One kind is disclosed using water extraction Portugal
The method that ethanol purification pigment is utilized after pigment in grape skin, this method can extract pigment from natural grape skin, but the party
Method obtain pigment purity it is not high and use industrial alcohol carry out purifying so that pigment cannot be used in direct cosmetics.Patent CN
106009763 A《A kind of method and its application that natural red colouring matter is extracted from dragon fruit》Disclose a kind of enzymatic isolation method and carry pigment
Method, this is simple to operation, but biology enzyme easily cause it is allergic, it is therefore desirable to by enzyme remove just can apply to cosmetics
In.As can be seen here, important practical significance will be had by developing a kind of preparation method of natural fruit pigment used for cosmetic.
The content of the invention
Invention solves the problems, such as to there is provided a kind of preparation method of natural fruit pigment used for cosmetic, system of the invention
Preparation Method is simple to operate and green, and obtained pigment purity is high, and is free of organic solvent, and skin compatibility is good.
To solve the above problems, the present invention provides following technical scheme：A kind of system of natural fruit pigment used for cosmetic
Preparation Method, it is characterised in that comprise the following steps：
（1）Removed the peel after fruit is cleaned into naturally dry, after remove seed, be transferred to after paste-manufacturing machine processing 10-15min and sample is broken into paste
Sample is ground into homogenate with homogenizer after shape；
（2）Weigh after 5kg lapping liquids mix with distilled water, in 200-400W ultrasonic powers, 100-200W microwave power and
Centrifuged under the conditions of 35-50 DEG C after microwave-ultrasonic 20-40min, residue is merged with after deionized water microwave-ultrasonic extraction 2-3 times again
After supernatant, supernatant is concentrated under reduced pressure to give natural fruit pigment crude extract concentrate；
（3）Centrifuge after vortex 20s after addition supermolecule solvent into crude extract concentrate, continue after upper phase is removed after formation two-phase
Centrifuged after adding eutectic reagent-salting liquid vortex 20s, take phase after forming two-phase and ethanol is added in upper phase by eutectic
Agent precipitate reclaims eutectic reagent, while, after ethanol is mutually taken out after vacuum distillation drying by pigmentolysis in ethanol
The fruit pigment used for cosmetic to high-purity.
Further, step（1）Described in fruit be mulberries, purple grape, cherry and dragon fruit in one kind；It is described
Homogenate processing time be 5-10min.
Further, step（2）Described in lapping liquid and distilled water volume ratio be 1：3-5；The fruit pigment slightly carries
The density of thing concentrate is 1.15-1.22g/mL.
Further, step（3）Described in supermolecule solvent be tetrahydrofuran-n-octyl alcohol-water, tetrahydrofuran-just oneself
One kind in alcohol-water, tetrahydrofuran-caprylic acid-water supermolecule solvent；There is substantial amounts of aggregation in the supermolecule solvent, and
The particle diameter of aggregation is 0.2-2um;The addition of the supermolecule solvent is the 10-15% of cumulative volume（V/V）.
Further, step（3）Described in eutectic reagent for Choline Chloride-urea, Choline Chloride-glycerine, beet
A kind of solution of transparent and homogeneous being thermally formed in 80 DEG C of water-baths in alkali-urea, glycine betaine-glycerine；Described salting liquid
For one kind in ammonium sulfate, sodium sulphate, dipotassium hydrogen phosphate；The concentration of the salting liquid is 0.25-0.5g/mL;The eutectic
The addition of reagent-salting liquid is the 40-60% of cumulative volume.
Further, step（3）In gross mass 1-5% natural lemon can be added in obtained described fruit pigment
The color of acid regulation pigment.
Further, step（3）Described in fruit pigment can be used for lipstick, profit lip night, lip gloss, lipblock, nail polish
Deng in cosmetics.
As a result of above-mentioned preparation method, the present invention has the advantages that compared with prior art：
The present invention significantly increases the efficiency from fruit extraction natural pigment using microwave-ultrasonic auxiliary extraction technology, shortens
Operating time；Prohibit characteristic using the limit of supermolecule solvent to remove the protein in fruit pigment extract and macromolecular substances precipitation
It is miscellaneous, improve the purity of pigment；The highly polar thing of fruit pigment extract kind is finally removed using eutectic reagent-aqueous two-phase extraction
Confrontation pigment is further purified so that obtained pigmented skin compatibility is good, non-stimulated and color controllable.Obtained through this patent
Natural fruit pigment can be directly used in the cosmetics such as lipstick, profit lip night, lip gloss, lipblock, nail polish.
Embodiment
With reference to specific embodiment, the invention will be further described.
Embodiment one
Dragon fruit is cleaned after removing the peel after naturally dry after remove seed, handled using paste-manufacturing machine after sample is broken into pasty state after 10min
Sample is ground after 10min into homogenate with homogenizer；Weigh after 5.0kg lapping liquids mix with 25L distilled water, in 400W ultrasound work(
Rate, centrifuged after microwave-ultrasonic 25min under the conditions of 200W microwave power and 30 DEG C, residue uses deionized water microwave-ultrasound again
After merging supernatant after extracting 3 times, supernatant is concentrated under reduced pressure to give density and slightly carried for 1.15-1.22g/mL natural fruits pigment
Thing concentrate；Centrifuge, formed after vortex 20s after tetrahydrofuran-caprylic acid-water supermolecule solvent of addition 10% into crude extract
The metabisulfite solution that the Choline Chloride-urea eutectic reagent -0.25g/mL for continuously adding 45% after upper phase is removed after two-phase is vortexed
Centrifuged after 20s, add ethanol in upper phase after the upper phase of formation two-phase taking-up reclaims eutectic reagent by eutectic agent precipitate, together
When by pigmentolysis in ethanol, high-purity fruit color used for cosmetic is obtained after ethanol is mutually taken out after vacuum distillation drying
Element.
Embodiment two
Cherry fruit is cleaned after removing the peel after naturally dry after remove seed, handled using paste-manufacturing machine after sample is broken into pasty state after 10min
Sample is ground after 12min into homogenate with homogenizer；Weigh after 5.0kg lapping liquids mix with 25L distilled water, in 400W ultrasound work(
Rate, centrifuged after microwave-super 30min under the conditions of 150W microwave power and 40 DEG C, residue is carried with deionized water microwave-ultrasound again
After merging supernatant after taking 3 times, it is 1.15-1.22g/mL natural fruit pigment crude extracts that supernatant is concentrated under reduced pressure to give into density
Concentrate；Centrifuged into crude extract after tetrahydrofuran-n-octyl alcohol-water supermolecule solvent of addition 15% after vortex 20s, form two
The sodium citrate solution that the Choline Chloride-glycerine eutectic reagent -0.35g/mL for continuously adding 50% after upper phase is removed after phase is vortexed
Centrifuged after 20s, add ethanol in upper phase after the upper phase of formation two-phase taking-up reclaims eutectic reagent by eutectic agent precipitate, together
When by pigmentolysis in ethanol, high-purity fruit color used for cosmetic is obtained after ethanol is mutually taken out after vacuum distillation drying
Element.
Embodiment three
After mulberry fruit is cleaned into naturally dry, sample is homogenized using breaking into sample after pasty state after paste-manufacturing machine processing 10min
Into homogenate after device grinding 10min；Weigh after 5kg lapping liquids mix with 22L distilled water, in 400W ultrasonic powers, 200W microwave
Centrifuged under the conditions of power and 40 DEG C after microwave-super 30min, residue merges after using deionized water microwave-ultrasonic extraction 3 times again
After clear liquid, it is 1.15-1.22g/mL natural fruit pigment crude extract concentrates that supernatant is concentrated under reduced pressure to give into density；To slightly carrying
Centrifuged in thing after tetrahydrofuran-n-hexyl alcohol-supermolecule solvent of addition 14% after vortex 20s, removing is upper mutually follow-up after forming two-phase
Centrifuged after the continuous glycine betaine-glycerine eutectic reagent -0.35g/mL for adding 50% sodium citrate solution vortex 20s, form two-phase
Ethanol is added after phase in upper phase eutectic agent precipitate is reclaimed into eutectic reagent in taking-up, while by pigmentolysis in ethanol
In, high-purity fruit pigment used for cosmetic is obtained after ethanol is mutually taken out after vacuum distillation drying.
Although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of changes, modification can be carried out to these embodiments, replace without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (7)
1. a kind of preparation method of natural fruit pigment used for cosmetic, it is characterised in that comprise the following steps：
（1）Removed the peel after fruit is cleaned into naturally dry, after remove seed, be transferred to after paste-manufacturing machine processing 10-15min and sample is broken into paste
Sample is ground into homogenate with homogenizer after shape；
（2）Weigh after 5kg lapping liquids mix with distilled water, in 200-400W ultrasonic powers, 100-200W microwave power and
Centrifuged under the conditions of 35-50 DEG C after microwave-ultrasonic 20-40min, residue is merged with after deionized water microwave-ultrasonic extraction 2-3 times again
After supernatant, supernatant is concentrated under reduced pressure to give natural fruit pigment crude extract concentrate；
（3）Centrifuge after vortex 20s after addition supermolecule solvent into crude extract concentrate, continue after upper phase is removed after formation two-phase
Centrifuged after adding eutectic reagent-salting liquid vortex 20s, take phase after forming two-phase and ethanol is added in upper phase by eutectic
Agent precipitate reclaims eutectic reagent, while, after ethanol is mutually taken out after vacuum distillation drying by pigmentolysis in ethanol
The fruit pigment used for cosmetic to high-purity.
A kind of 2. preparation method of natural fruit pigment used for cosmetic according to claim 1, it is characterised in that step
（1）Described in fruit be mulberries, purple grape, cherry and dragon fruit in one kind；Described homogenate processing time is 5-
10min。
A kind of 3. preparation method of natural fruit pigment used for cosmetic according to claim 1, it is characterised in that step
（2）Described in lapping liquid and distilled water volume ratio be 1：3-5；The density of the fruit pigment crude extract concentrate is 1.15-
1.22g/mL。
A kind of 4. preparation method of natural fruit pigment used for cosmetic according to claim 1, it is characterised in that step
（3）Described in supermolecule solvent for tetrahydrofuran-n-octyl alcohol-water, tetrahydrofuran-n-hexyl alcohol-water, tetrahydrofuran-caprylic acid-
One kind in water supermolecule solvent；There is substantial amounts of aggregation in the supermolecule solvent, and the particle diameter of aggregation is 0.2-2um；
The addition of the supermolecule solvent is the 10-15% of cumulative volume（V/V）.
A kind of 5. preparation method of natural fruit pigment used for cosmetic according to claim 1, it is characterised in that step
（3）Described in eutectic reagent be Choline Chloride-urea, Choline Chloride-glycerine, glycine betaine-urea, in glycine betaine-glycerine
A kind of transparent and homogeneous being thermally formed in 80 DEG C of water-baths solution；Described salting liquid is ammonium sulfate, sodium sulphate, phosphoric acid hydrogen
One kind in dipotassium；The concentration of the salting liquid is 0.25-0.5g/mL;The addition of the eutectic reagent-salting liquid is
The 40-60% of cumulative volume.
A kind of 6. preparation method of natural fruit pigment used for cosmetic according to claim 1, it is characterised in that step
（3）In can add in obtained described fruit pigment gross mass 1-5% natural lemon acid regulation pigment color.
A kind of 7. preparation method of natural fruit pigment used for cosmetic according to claim 1, it is characterised in that step
（3）Described in fruit pigment can be used in lipstick, profit lip night, lip gloss, lipblock, the cosmetics such as nail polish.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711357450.6A CN107854366A (en) | 2017-12-16 | 2017-12-16 | A kind of preparation method of natural fruit pigment used for cosmetic |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711357450.6A CN107854366A (en) | 2017-12-16 | 2017-12-16 | A kind of preparation method of natural fruit pigment used for cosmetic |
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| CN107854366A true CN107854366A (en) | 2018-03-30 |
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| CN201711357450.6A Pending CN107854366A (en) | 2017-12-16 | 2017-12-16 | A kind of preparation method of natural fruit pigment used for cosmetic |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108619022A (en) * | 2018-06-20 | 2018-10-09 | 钟里梅 | A kind of fruit extraction lip care glaze formula |
| CN108902678A (en) * | 2018-06-06 | 2018-11-30 | 广东皇麦世家食品有限公司 | A kind of preparation method of the weight-reducing oatmeal containing algal polysaccharides |
| CN109322180A (en) * | 2018-09-11 | 2019-02-12 | 泉州市缘创环保科技有限公司 | A kind of colouring method of natural salt algae beta carotene |
| CN110236989A (en) * | 2019-07-25 | 2019-09-17 | 林燕 | A kind of fruit pigment and fruity lipstick and preparation method thereof |
| CN110643196A (en) * | 2019-09-11 | 2020-01-03 | 暨南大学 | Extraction and separation method of anthocyanin |
| CN113389069A (en) * | 2021-07-02 | 2021-09-14 | 浙江理工大学 | Blue-violet natural dye color matching and dyeing method based on natural eutectic solvent and microwave extraction technology |
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| CN101273958A (en) * | 2007-03-29 | 2008-10-01 | 维尔维廷布尼有限公司 | Cosmetic and dermatological formulations with natural pigments and methods of use |
| CN105997603A (en) * | 2016-05-04 | 2016-10-12 | 广州丹奇日用化工厂有限公司 | Lipstick preventing allergy |
| CN107163098A (en) * | 2017-06-28 | 2017-09-15 | 江苏优之食品有限公司 | A kind of extracting method of natural high-purity mogroside |
| CN107184461A (en) * | 2017-05-23 | 2017-09-22 | 林燕 | A kind of extracting method of pawpaw polyphenol |
| CN107412065A (en) * | 2017-08-15 | 2017-12-01 | 刘后伟 | A kind of lipstick of the pigment containing dragon fruit and preparation method thereof |
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2017
- 2017-12-16 CN CN201711357450.6A patent/CN107854366A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101273958A (en) * | 2007-03-29 | 2008-10-01 | 维尔维廷布尼有限公司 | Cosmetic and dermatological formulations with natural pigments and methods of use |
| CN105997603A (en) * | 2016-05-04 | 2016-10-12 | 广州丹奇日用化工厂有限公司 | Lipstick preventing allergy |
| CN107184461A (en) * | 2017-05-23 | 2017-09-22 | 林燕 | A kind of extracting method of pawpaw polyphenol |
| CN107163098A (en) * | 2017-06-28 | 2017-09-15 | 江苏优之食品有限公司 | A kind of extracting method of natural high-purity mogroside |
| CN107412065A (en) * | 2017-08-15 | 2017-12-01 | 刘后伟 | A kind of lipstick of the pigment containing dragon fruit and preparation method thereof |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108902678A (en) * | 2018-06-06 | 2018-11-30 | 广东皇麦世家食品有限公司 | A kind of preparation method of the weight-reducing oatmeal containing algal polysaccharides |
| CN108619022A (en) * | 2018-06-20 | 2018-10-09 | 钟里梅 | A kind of fruit extraction lip care glaze formula |
| CN109322180A (en) * | 2018-09-11 | 2019-02-12 | 泉州市缘创环保科技有限公司 | A kind of colouring method of natural salt algae beta carotene |
| CN110236989A (en) * | 2019-07-25 | 2019-09-17 | 林燕 | A kind of fruit pigment and fruity lipstick and preparation method thereof |
| CN110643196A (en) * | 2019-09-11 | 2020-01-03 | 暨南大学 | Extraction and separation method of anthocyanin |
| CN113389069A (en) * | 2021-07-02 | 2021-09-14 | 浙江理工大学 | Blue-violet natural dye color matching and dyeing method based on natural eutectic solvent and microwave extraction technology |
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