CN107854361A - The application of the sub-critical extraction thing of the flaxseed for state of not germinateing - Google Patents
The application of the sub-critical extraction thing of the flaxseed for state of not germinateing Download PDFInfo
- Publication number
- CN107854361A CN107854361A CN201711308402.8A CN201711308402A CN107854361A CN 107854361 A CN107854361 A CN 107854361A CN 201711308402 A CN201711308402 A CN 201711308402A CN 107854361 A CN107854361 A CN 107854361A
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- flaxseed
- sub
- preparation composition
- dermatologic preparation
- skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/55—Linaceae (Flax family), e.g. Linum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Abstract
The invention belongs to skin care field, discloses the application of the sub-critical extraction thing of the flaxseed for state of not germinateing.Disclosed Dermatologic preparation composition contains the sub-critical extraction thing of the flaxseed for state of not germinateing as active ingredient, wherein, the sub-critical extraction thing of flaxseed obtains by the following method：Flaxseed is prepared, then utilizes sub-critical extraction device to decompose flaxseed, effective component extracting under 50 200MPa high pressure flaxseed.Also disclose application of the sub-critical extraction thing of the flaxseed for state of not germinateing as active ingredient in Dermatologic preparation composition is prepared.The present invention can obtain skin pore shrinks and acne skin improves and other effects.
Description
It is on April 23rd, 2012 applying date that the application, which is, Application No. 201210120600.2, entitled " containing flax
The divisional application of the Chinese invention patent application of the Dermatologic preparation composition of benevolence extract ".
Technical field
The present invention relates to Dermatologic preparation composition of the flaxseed extract as active ingredient is contained, specifically, relate to
And the application of the sub-critical extraction thing of the flaxseed for state of not germinateing.
Background technology
The horn cell of outermost layer-epidermis of skin persistently carries out cell differentiation, the cell of differentiation with 28 days for the cycle, according to
The secondary order according to spinous layer, stratum granulosum, cuticula comes off.As these cell cycles can not be smoothed out, cuticula will be accumulated,
Pore will be blocked, the sebum of secretion is hardened in pore, produces inflammation or acne.If it is iteratively produced asking for these pores
Topic, will influence the corium around pore, cause to accelerate pore to expand.In addition, if the Excess sebum production of sebaceous glands, excessively
Sebum can also produce pore problem, cause pore expand and acne.
These pores will make overall skin seem coarse, it appears that to follow the string, so pore once expanding once
Contraction is one in the problem for needed most in skin problem solution.
Flax (Linum usitatissimum L.) is linaceous annual herb, a height of 30-100 centimetres, leaf
It is to stagger and wide sector.Flax is livid purple color or white, and fruit is that capsule is spherical, and seed is average flat avette, in Huang
Brown.Linseed is also referred to as flaxseed, and mainly for the preparation of linseed oil, and linseed oil is used to print with ink, oil painting paint.
In the patent of the composition of the skin antioxidant effect of conventional related flaxseed, used as hair with oil component
Cross.But it is not common flax benevolence, the pore of flaxseed extract and subcritical flaxseed extract for germination shrinks
Do not reported with acne improvement.
Patent document：Ebrean Registered Patent publication the 10-0909206th
The content of the invention
It was found by the inventors of the present invention that the extract of the flaxseed of germination or the sub-critical extraction thing of flaxseed are as effective
Composition pore refining size, improves acne skin, thus completes the present invention containing that sometimes, can reduce sebum amount.
Change it is therefore an object of the present invention to provide and contain pore contraction and acne of the flaxseed extract as active ingredient
The Dermatologic preparation composition that kind effect protrudes.
Shunk the present invention relates to the sebum reduction for containing flaxseed extract as active ingredient, pore and acne improves
Use Dermatologic preparation composition.
Moreover, it relates to the Dermatologic preparation composition that the flaxseed extract that germinates is contained as active ingredient.
Moreover, the present invention relates to the skin for containing the flaxseed sub-critical extraction thing for state of not germinateing as active ingredient
Preparation composition for external use.
The present invention is illustrated further below.
The flaxseed used in the present invention contains omega-3 fatty acid, protein, mineral matter, vitamin etc., particularly contains
Two molecule n- phenyl propylsThe natural goods being combined into the β positions of n- propyl side chains-wooden phenol
Plain (lignan).The lignan composition contained in flaxseed extract helps to reduce sebum amount, pore refining, improves acne skin
Skin.
The flaxseed used in the present invention is preferably the flaxseed to germinate.Using germination flaxseed when, significantly improve wood
Phenol cellulose content, the content to active ingredient necessary to biological phenomena is improved, so can obtain reducing sebum amount, pore refining, change
The good result of kind acne skin.
The conventional method in the field can be used in the germination of above-mentioned flaxseed.For example, at 21-27 DEG C, preferably in 25 DEG C of water
After middle addition flaxseed, kept for 5-8 hours, preferably 7 hours, then flaxseed is immersed in water, at 25-30 DEG C, preferably existed
Under 27 DEG C of temperature conditionss, implement illumination condition and dark condition repeatedly, germinateed.Now, it is small to implement 17-19 for illumination condition
When, dark condition implements 5-7 hours；Preferably, illumination condition is implemented 18 hours, and dark condition is implemented 6 hours, cultivates and continues 5-
7 days, preferably cultivate 6 days and germinate.
The extraction of above-mentioned flaxseed extract is made using the general extraction methods in the field, it is preferred to use solvent extraction
Method, super critical extraction or sub-sigmaritical extraction method, more preferably sub-sigmaritical extraction method.Sub-sigmaritical extraction method is, in the liquid of solvent
Under the conditions of temperature and pressure below the critical point of body and gas coexistence, the extraction method that is used as Extraction solvent, this hair
The above-mentioned solvent of bright middle conduct uses water.In addition, in super critical extraction, due to using carbon dioxide, in order to extract polar substances,
Organic solvent is needed as secondary solvent.Therefore, compared with super critical extraction, sub-sigmaritical extraction method, which has, does not need these attached
The advantages of adding secondary organic solvent, moreover, using water as Extraction solvent, reaction can also be hydrolyzed.Faced by these Asias
Boundary's extraction method can obtain the extract of high-purity, therefore in the sub-critical extraction thing of the flaxseed containing germination, can be subtracted
Few sebum amount, pore refining, the good result for improving acne skin.
The flaxseed extract using sub-sigmaritical extraction method used in the present invention is specifically prepared in the following manner.By flax
Benevolence in 50-200MPa, preferably under 100MPa high pressure, decomposes flaxseed, effective component extracting using sub-critical extraction device.
When pressure is less than 50MPa, it is impossible to abundant effective component extracting, and when pressure is more than 200MPa, relatively high pressure, extracts active ingredients
Amount increase is simultaneously little, so being extracted under the pressure of above range.After extraction, in the filter with 1.2 μm of holes
Filtering once, in the filter with 0.45 μm of hole is filtered once, and one is filtered in the filter with 0.2 μm of hole
It is secondary, foreign matter and microorganism are removed, obtains subcritical flaxseed extract.
The flaxseed extract of the present invention, the total amount of relative combination, can contain 0.01-97 weight %, preferably comprise 60-
90 weight % flaxseed extract.When the content of extract is less than 0.01 weight %, it is impossible to good result is obtained, and more than 97
During weight %, side effect and dissolved within dosage form degree problem can be produced.
The composition of the present invention is due to containing germination flaxseed extract as active ingredient, so preventing with skin aging
Only effect, antioxidant effect, skin elasticity enhancing effect, wrinkle of skin improvement, by blood circulation improve complexion change
Kind effect, skin irritatin alleviation effects, dynamic equilibrium improve effect, elastic force enhancing effect, skin resurfacing effect, dead skin and remove effect
Fruit, skin wastes cleaning effect, cutin improvement, skin tightening effect, regulating effect, whitening effect.
The composition of the present invention carries out formulation containing the medium allowed on cosmeceutical or dermatology or basic reagent
Change.Local all formulations can be applied to, are disperseed for example, solution, gel, solid, anhydrous paste, oil phase can be provided as
In the small of the emulsion of aqueous phase, suspension, microemulsion, microcapsules, subparticle ball or ionic (liposome) and nonionic
Capsule dispersantForm, Huo Zheshuan, toner, emulsion, powder, ointment, spraying and hide flaw rod state.Separately
Outside, the form of spraying (airosol) composition of foam form or the propellant further containing compression can also be provided.This
A little compositions can be prepared according to the usual method of this area.
In addition, the composition of the present invention can contain fatty material, organic solvent, lytic agent, concentrating agents, gel, softening
Agent, antioxidant, suspending agent, stabilizer, foaming agent (foaming agent), aromatic, surfactant, water, ionic or
It is nonionic emulsifier, filler, metal ion disintegrant, chelating agent, preservative agent, vitamin, blocking agent, wetting agent, required
The cosmetic for any other compositions commonly used in oil, dyestuff, pigment, hydrophily or lipophile activating agent, lipid vesicle and cosmetics
Usually used adjuvant in conduct and learning or dermatology.Above-mentioned adjuvant contains generally to be made in cosmeceutical or dermatology
Amount.
In addition, the composition of the present invention contains skin absorption enhancement material to increase skin improvement effects.
The composition of the present invention is not influenceing the scope of the object of the invention in addition to above-mentioned germination flaxseed extract
It is interior, preferably containing the other compositions that can strengthen above-mentioned skin sparing effect.
The Dermatologic preparation composition containing flaxseed extract of the present invention is used for by the characteristic of flaxseed extract
During human body skin, pore refining, sebum secretion amount is reduced, and improve acne skin.Particularly, using the flaxseed of germination state
During extract, lignan content is improved, when being extracted using sub-sigmaritical extraction method, obtains high-purity extract, so with good
Pore shrink, sebum reduce and acne skin improve.
Embodiment
Below by embodiment and test example, composition of the invention and effect are further illustrated.These embodiments and experiment
Example is intended merely to help the understanding of the present invention, and scope of the invention and scope are not limited to this.
The preparation of the germination flaxseed extract of preparation example 1
After adding flaxseed in 25 DEG C of water, kept for 7 hours, then flaxseed is immersed in water, in 27 DEG C of temperature
Under the conditions of degree, implement illumination condition repeatedly 18 hours and dark condition is germinateed for 6 hours, the flaxseed to be germinateed after 6 days.
The flaxseed of above-mentioned germination is put into the solvent of 70 weight % Purified Waters and 30 weight % ethanol, in 25 DEG C of decentralizations
Put 6 hours, extract active component.After extraction, filtered in the filter with 1.2 μm of holes once, with 0.45 μm of hole
Filtered in the filter of gap once, eliminate foreign matter, finally using the filter with 0.2 μm of hole, eliminated microorganism, sent out
Bud flaxseed extract.
The preparation of the subcritical germination flaxseed extract of preparation example 2
The germination flaxseed that will be obtained with the above-mentioned same procedure of preparation example 1, using sub-critical extraction device, 100MPa's
Effective component extracting under high pressure.After extraction, filtered in the filter with 1.2 μm of holes once, with 0.45 μm of hole
Filter in filter once, filtered in the filter with 0.2 μm of hole once, eliminate foreign matter and microorganism, obtain Asia
Critical germination flaxseed extract.
The preparation of the subcritical flaxseed extract of preparation example 3
After the flaxseed for state of not germinateing is crushed, using sub-critical extraction device, being extracted under 100MPa high pressure has
Imitate composition.After extraction, filtered in the filter with 1.2 μm of holes once, the mistake in the filter with 0.45 μm of hole
Filter once, is filtered once in the filter with 0.2 μm of hole, is eliminated foreign matter and microorganism, is obtained subcritical flaxseed and carry
Take thing.
Embodiment 1-3 and comparative example 1-2
In order to evaluate the pore contractive effect of the present composition, prepare with the embodiment 1-3 such as table 1 below composition and right
Ratio 1-2 cosmetic water aqua type.Germinate flaxseed extract, subcritical germination flaxseed extract and subcritical flaxseed
For extract using above-mentioned preparation example 1-2 and the prepared product of contrast preparation example 1, flaxseed extract is that use is purchased from Durae companies
Buy.
Table 1
The pore of the germination flaxseed extract of test example 1 reduces effect and confirmed
The selected women 23 of more than 30 years old worried because of pore, by the prescription of embodiment 1, it is obvious that pore is applied daily
Position, after coating 2 weeks, pore size is evaluated using skin contact pore analysis program, will be average using pore analysis program
Pore size is divided into Three Estate, counts the number of each group, the results are shown in table 2 below.
Table 2
It can be seen that from the result of upper table 2, cosmetic composition of the invention can effectively reduce pore size.
The sebum amount of the germination flaxseed extract of test example 2 reduces effect and confirmed
The selected masculinity and femininity 10 worried because of hypersteatosis, by the prescription of embodiment 1, applies face daily
The position of hypersteatosis, after applying 4 weeks, sebumeter (Courage＆Khazaka companies, Germany) is utilized to determine sebum
Amount, the results are shown in table 3 below.
Table 3
It can be seen that from the result of upper table 3, cosmetic composition of the invention can effectively suppress sebum.
The sense evaluation of the pore contractive effect of test example 3
20 for worrying big pore in the women of 25-30 year, with aqueous phase of commonly making up with application method using above-mentioned
Embodiment 1-3 and comparative example 1-2 toner, persistently with four time-of-weeks, according to the opinion of user, by skin improve situation with
Following evaluation criterion is judged.The results are shown in table 4 below.
Evaluation criterion
+++：Very good improvement；
++：Obvious improvement；
+：Some improvements；
±：There is no improvement, but do not deteriorate；
-：There is no improvement, and deteriorate.
Table 4
As shown in the result of above-mentioned table 4, compared to the comparative example 1 not containing flaxseed extract and contain common flax benevolence
The comparative example 2 of extract, carried containing germination flaxseed extract, subcritical germination flaxseed extract and subcritical flaxseed
The embodiment 1-3 of thing is taken, can confirm that there is rapid and good pore contractive effect.
The sense evaluation of the acne improvement of test example 4
20 for worrying acne in the women of 19-26 year, commonly to make up, aqueous phase uses above-mentioned reality with application method
A 1-3 and comparative example 1-2 toner are applied, persistently with four time-of-weeks, according to the opinion of user, skin is improved into situation with such as
Lower evaluation criterion is judged.The results are shown in table 5 below.
Evaluation criterion
+++：Very good improvement；
++：Obvious improvement；
+：Some improvements；
±：There is no improvement, but do not deteriorate；
-：There is no improvement, and deteriorate.
Table 5
As shown in the result of above-mentioned table 5, compared to the comparative example 1 not containing flaxseed extract and contain common flax benevolence
The comparative example 2 of extract, carried containing germination flaxseed extract, subcritical germination flaxseed extract and subcritical flaxseed
The embodiment 1-3 of thing is taken, can confirm that there is rapid and good acne skin improvement.
Claims (8)
1. Dermatologic preparation composition, it is characterised in that said composition contains the sub-critical extraction of the flaxseed for state of not germinateing
Thing as active ingredient,
Wherein, the sub-critical extraction thing of flaxseed obtains by the following method：Flaxseed is prepared, then faces flaxseed using Asia
Boundary's extraction element decomposes flaxseed, effective component extracting under 50-200MPa high pressure.
2. Dermatologic preparation composition according to claim 1, wherein, pressure 100MPa.
3. Dermatologic preparation composition according to claim 1 or 2, wherein, the total amount of relative combination, the flaxseed
The content of extract is 0.01-97 weight %.
4. Dermatologic preparation composition according to claim 1 or 2, wherein, the composition is that skin pore shrinks use
Dermatologic preparation composition.
5. Dermatologic preparation composition according to claim 1 or 2, wherein, the composition is sebum reduction skin
Preparation composition for external use.
6. Dermatologic preparation composition according to claim 1 or 2, wherein, the composition is that acne skin improves use
Dermatologic preparation composition.
7. the sub-critical extraction thing of the flaxseed for state of not germinateing is as active ingredient in Dermatologic preparation composition is prepared
Using,
Wherein, the sub-critical extraction thing of flaxseed obtains by the following method：Flaxseed is prepared, then faces flaxseed using Asia
Boundary's extraction element decomposes flaxseed, effective component extracting under 50-200MPa high pressure.
8. application according to claim 7, wherein, the Dermatologic preparation composition is for reducing pore, sebum is reduced,
Skin pore shrinks or acne skin improves.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2012-0009326 | 2012-01-31 | ||
| KR1020120009326A KR101916824B1 (en) | 2012-01-31 | 2012-01-31 | Skin external composition comprising Linum usitatissimum L. seed extract |
| CN201210120600.2A CN103222937B (en) | 2012-01-31 | 2012-04-23 | Dermatologic preparation composition containing flaxseed extract |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210120600.2A Division CN103222937B (en) | 2012-01-31 | 2012-04-23 | Dermatologic preparation composition containing flaxseed extract |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107854361A true CN107854361A (en) | 2018-03-30 |
Family
ID=48833737
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210120600.2A Active CN103222937B (en) | 2012-01-31 | 2012-04-23 | Dermatologic preparation composition containing flaxseed extract |
| CN201711308402.8A Pending CN107854361A (en) | 2012-01-31 | 2012-04-23 | The application of the sub-critical extraction thing of the flaxseed for state of not germinateing |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210120600.2A Active CN103222937B (en) | 2012-01-31 | 2012-04-23 | Dermatologic preparation composition containing flaxseed extract |
Country Status (2)
| Country | Link |
|---|---|
| KR (1) | KR101916824B1 (en) |
| CN (2) | CN103222937B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109846788A (en) * | 2019-03-29 | 2019-06-07 | 湖南御家化妆品制造有限公司 | A kind of moisturizing, moisturizing and/or antibacterial composition and its cosmetics of preparation |
| US20240050355A1 (en) * | 2022-08-11 | 2024-02-15 | Folashade Simpson | Topical skin treatment composition |
| CN115778859A (en) * | 2022-12-23 | 2023-03-14 | 李克明 | Skin conditioner |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129311A (en) * | 2007-09-18 | 2008-02-27 | 陈苏莉 | Creamier formulation containing turmeric and extractive of flax seed and method of producing the same |
| FR2947727A1 (en) * | 2009-07-07 | 2011-01-14 | Sothys Paris | Composition, useful for treating skin aging, wrinkles and fine line on the skin of the face, neck and/or neckline, comprises combination of an active agent of quercetol type and a protein hydrolyzate of cotton or its extract and excipient |
| CN102276665A (en) * | 2011-06-21 | 2011-12-14 | 晨光生物科技集团天津有限公司 | Method of extracting flax lignin from flax seed cake |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2452997A1 (en) * | 2001-07-06 | 2003-01-16 | Canadian Organic Sprout Company | Flax sprouts and sprouting method |
| US7943190B2 (en) * | 2005-05-13 | 2011-05-17 | Her Majesty the Queen in Right in Canada as Represented by the Minister of Agriculture and Agri-Food Canada | Extraction of phytochemicals |
| KR101239432B1 (en) * | 2005-09-06 | 2013-03-06 | 바이오그린 에이/에스 | Demucilaged flax sprouts and their by-product as well as production and application thereof |
| HU227873B1 (en) * | 2007-06-18 | 2012-05-29 | Biogreen As | Emulsions based of plant-germ, process for their production and use |
| JP5329830B2 (en) * | 2008-03-31 | 2013-10-30 | 株式会社コーセー | SCF secretion inhibitor and sebum secretion inhibitor |
| US20100113352A1 (en) * | 2008-11-06 | 2010-05-06 | Elliott Millstein | Retinol formulations and methods for their use |
| US8178106B2 (en) * | 2009-03-30 | 2012-05-15 | Mary Kay Inc. | Topical skin care formulations |
| WO2011099964A1 (en) * | 2010-02-10 | 2011-08-18 | Biopelle, Inc. | Retinol formulations and methods for their use |
| CN102000009B (en) * | 2010-11-12 | 2012-06-06 | 中国农业科学院油料作物研究所 | Flaxseed oil-containing cleansing cream and preparation method thereof |
-
2012
- 2012-01-31 KR KR1020120009326A patent/KR101916824B1/en active IP Right Grant
- 2012-04-23 CN CN201210120600.2A patent/CN103222937B/en active Active
- 2012-04-23 CN CN201711308402.8A patent/CN107854361A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129311A (en) * | 2007-09-18 | 2008-02-27 | 陈苏莉 | Creamier formulation containing turmeric and extractive of flax seed and method of producing the same |
| FR2947727A1 (en) * | 2009-07-07 | 2011-01-14 | Sothys Paris | Composition, useful for treating skin aging, wrinkles and fine line on the skin of the face, neck and/or neckline, comprises combination of an active agent of quercetol type and a protein hydrolyzate of cotton or its extract and excipient |
| CN102276665A (en) * | 2011-06-21 | 2011-12-14 | 晨光生物科技集团天津有限公司 | Method of extracting flax lignin from flax seed cake |
Also Published As
| Publication number | Publication date |
|---|---|
| KR101916824B1 (en) | 2018-11-08 |
| CN103222937B (en) | 2018-08-21 |
| CN103222937A (en) | 2013-07-31 |
| KR20130088226A (en) | 2013-08-08 |
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Application publication date: 20180330 |