CN107849737B - 肽文库构建方法及相关载体 - Google Patents

肽文库构建方法及相关载体 Download PDF

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CN107849737B
CN107849737B CN201580081102.3A CN201580081102A CN107849737B CN 107849737 B CN107849737 B CN 107849737B CN 201580081102 A CN201580081102 A CN 201580081102A CN 107849737 B CN107849737 B CN 107849737B
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peptide
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peptides
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library
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CN107849737A (zh
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王珠银
李向群
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Hohai University HHU
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1093General methods of preparing gene libraries, not provided for in other subgroups
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/10Libraries containing peptides or polypeptides, or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/06Biochemical methods, e.g. using enzymes or whole viable microorganisms

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  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
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  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Peptides Or Proteins (AREA)
CN201580081102.3A 2015-07-03 2015-07-03 肽文库构建方法及相关载体 Active CN107849737B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2015/083260 WO2017004745A1 (en) 2015-07-03 2015-07-03 Peptide library constructing method and related vectors

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CN107849737A CN107849737A (zh) 2018-03-27
CN107849737B true CN107849737B (zh) 2020-06-26

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US (1) US12012595B2 (enExample)
EP (1) EP3294934B1 (enExample)
JP (1) JP6653979B2 (enExample)
CN (1) CN107849737B (enExample)
AU (1) AU2015401336B2 (enExample)
CA (1) CA2990023C (enExample)
DK (1) DK3294934T3 (enExample)
ES (1) ES2777329T3 (enExample)
PL (1) PL3294934T3 (enExample)
PT (1) PT3294934T (enExample)
WO (1) WO2017004745A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3596106B1 (en) * 2017-04-26 2021-08-11 Hunan Zonsen Peplib Biotech Co., Ltd Peptide library constructing method
US11830582B2 (en) 2018-06-14 2023-11-28 University Of Miami Methods of designing novel antibody mimetics for use in detecting antigens and as therapeutic agents
CN110055594A (zh) * 2019-05-10 2019-07-26 艾柏森(江苏)生物科技有限公司 一种噬菌粒展示系统构建多肽文库方法
WO2020251615A1 (en) * 2019-06-14 2020-12-17 University Of Miami Methods of designing novel antibody mimetics for use in detecting antigens and as therapeutic agents
CN118420719B (zh) * 2023-04-10 2025-06-10 湖南中晟全肽生物科技股份有限公司 人cd200受体的拮抗剂结合多肽分子及其应用
CN116925206B (zh) * 2023-07-18 2024-04-23 湖南中晟全肽生物科技股份有限公司 Gitr相关的多肽及其应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003040391A2 (en) * 2001-11-08 2003-05-15 University College London Method for producing and identifying soluble protein domains
CN101310023A (zh) * 2005-07-15 2008-11-19 韩国生命工学研究院 用于生产重组蛋白质的翻译融合配偶体文库和从中筛选的翻译融合配偶体
CN101970691A (zh) * 2007-12-19 2011-02-09 森托科尔奥索生物科技公司 人非抗体肽或蛋白质噬菌体文库
WO2013063366A2 (en) * 2011-10-27 2013-05-02 Stc.Unm Methods for screening viral like particles and identifying neutralizing epitopes and related vaccines, constructs, and libraries

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7105341B2 (en) * 2000-03-06 2006-09-12 Rigel Pharmaceuticals. Inc. In vivo production of cyclic peptides
AT503474A1 (de) * 2006-03-29 2007-10-15 Univ Wien Bodenkultur Peptidbibliothek
GB0712245D0 (en) * 2007-06-25 2007-08-01 Cythera Technologies Ltd Combinatorial libraries and related methods
CN102947324A (zh) * 2010-01-29 2013-02-27 阿切尔丹尼尔斯密德兰公司 结合有工业意义的小分子的肽结构域
US9506167B2 (en) * 2011-07-29 2016-11-29 Ginkgo Bioworks, Inc. Methods and systems for cell state quantification

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003040391A2 (en) * 2001-11-08 2003-05-15 University College London Method for producing and identifying soluble protein domains
CN101310023A (zh) * 2005-07-15 2008-11-19 韩国生命工学研究院 用于生产重组蛋白质的翻译融合配偶体文库和从中筛选的翻译融合配偶体
CN101970691A (zh) * 2007-12-19 2011-02-09 森托科尔奥索生物科技公司 人非抗体肽或蛋白质噬菌体文库
WO2013063366A2 (en) * 2011-10-27 2013-05-02 Stc.Unm Methods for screening viral like particles and identifying neutralizing epitopes and related vaccines, constructs, and libraries

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WO2017004745A1 (en) 2017-01-12
EP3294934A1 (en) 2018-03-21
EP3294934B1 (en) 2020-01-01
ES2777329T3 (es) 2020-08-04
CA2990023A1 (en) 2017-01-12
PT3294934T (pt) 2020-02-06
JP6653979B2 (ja) 2020-02-26
EP3294934A4 (en) 2018-03-28
CA2990023C (en) 2021-11-09
DK3294934T3 (da) 2020-03-23
AU2015401336A1 (en) 2018-01-04
US12012595B2 (en) 2024-06-18
JP2018518991A (ja) 2018-07-19
PL3294934T3 (pl) 2020-09-07
US20180179519A1 (en) 2018-06-28
CN107849737A (zh) 2018-03-27
AU2015401336B2 (en) 2019-09-19

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