CN107847743B - 刺激肾神经的系统 - Google Patents

刺激肾神经的系统 Download PDF

Info

Publication number
CN107847743B
CN107847743B CN201680042513.6A CN201680042513A CN107847743B CN 107847743 B CN107847743 B CN 107847743B CN 201680042513 A CN201680042513 A CN 201680042513A CN 107847743 B CN107847743 B CN 107847743B
Authority
CN
China
Prior art keywords
renal
subject
blood pressure
heart rate
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201680042513.6A
Other languages
English (en)
Chinese (zh)
Other versions
CN107847743A (zh
Inventor
S·魏斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Koninklijke Philips NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips NV filed Critical Koninklijke Philips NV
Publication of CN107847743A publication Critical patent/CN107847743A/zh
Application granted granted Critical
Publication of CN107847743B publication Critical patent/CN107847743B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36017—External stimulators, e.g. with patch electrodes with leads or electrodes penetrating the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1477—Needle-like probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0502—Skin piercing electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00434—Neural system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00505—Urinary tract
    • A61B2018/00511—Kidney
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00839—Bioelectrical parameters, e.g. ECG, EEG
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2218/00—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2218/001—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body having means for irrigation and/or aspiration of substances to and/or from the surgical site
    • A61B2218/002—Irrigation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2505/00—Evaluating, monitoring or diagnosing in the context of a particular type of medical care
    • A61B2505/05—Surgical care

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Cardiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Otolaryngology (AREA)
  • Business, Economics & Management (AREA)
  • Physiology (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Robotics (AREA)
  • Vascular Medicine (AREA)
  • General Business, Economics & Management (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Electrotherapy Devices (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
CN201680042513.6A 2015-07-21 2016-07-12 刺激肾神经的系统 Active CN107847743B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15177702.6 2015-07-21
EP15177702 2015-07-21
PCT/EP2016/066462 WO2017012907A1 (en) 2015-07-21 2016-07-12 System for stimulating renal nerves

Publications (2)

Publication Number Publication Date
CN107847743A CN107847743A (zh) 2018-03-27
CN107847743B true CN107847743B (zh) 2022-06-10

Family

ID=53682589

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201680042513.6A Active CN107847743B (zh) 2015-07-21 2016-07-12 刺激肾神经的系统

Country Status (5)

Country Link
US (3) US11547480B2 (enExample)
EP (1) EP3325086B1 (enExample)
JP (1) JP6998295B2 (enExample)
CN (1) CN107847743B (enExample)
WO (1) WO2017012907A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150111918A1 (en) 2012-03-08 2015-04-23 Medtronic Ardian Luxembourg S.a.r.l Immune system neuromodulation and associated systems and methods
US10610292B2 (en) 2014-04-25 2020-04-07 Medtronic Ardian Luxembourg S.A.R.L. Devices, systems, and methods for monitoring and/or controlling deployment of a neuromodulation element within a body lumen and related technology
EP4389044A3 (en) 2014-10-01 2024-09-11 Medtronic Ardian Luxembourg S.à.r.l. Systems and methods for evaluating neuromodulation therapy via hemodynamic responses
US20190069949A1 (en) 2014-12-03 2019-03-07 Metavention, Inc. Systems and methods for modulatng nerves or other tissue
US10667736B2 (en) 2014-12-17 2020-06-02 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for assessing sympathetic nervous system tone for neuromodulation therapy
CN111511302B (zh) 2017-11-17 2024-09-17 美敦力Af卢森堡有限责任公司 用于具有增强的神经靶向的神经调节的系统、设备以及相关联的方法
US20190223946A1 (en) 2018-01-24 2019-07-25 Medtronic Ardian Luxembourg S.A.R.L. Systems, devices, and associated methods for neuromodulation in heterogeneous tissue environments
US12082917B2 (en) 2018-01-24 2024-09-10 Medtronic Ireland Manufacturing Unlimited Company Systems, devices, and methods for assessing efficacy of renal neuromodulation therapy
US10959669B2 (en) 2018-01-24 2021-03-30 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for assessing the efficacy of neuromodulation therapy
US11253189B2 (en) 2018-01-24 2022-02-22 Medtronic Ardian Luxembourg S.A.R.L. Systems, devices, and methods for evaluating neuromodulation therapy via detection of magnetic fields
US10786306B2 (en) 2018-01-24 2020-09-29 Medtronic Ardian Luxembourg S.A.R.L. Denervation therapy
US11633120B2 (en) 2018-09-04 2023-04-25 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for assessing efficacy of renal neuromodulation therapy
US12020791B2 (en) 2018-10-26 2024-06-25 Koninklijke Philips N.V. Determination of a treatment response index
CN114224385B (zh) * 2022-02-28 2022-05-31 深圳高性能医疗器械国家研究院有限公司 一种无创肾交感神经活性检测系统及方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101443072A (zh) * 2006-03-06 2009-05-27 阿迪安公司 双侧肾神经调制的方法和装置
CN101940815A (zh) * 2004-10-05 2011-01-12 阿迪安公司 肾神经调节的方法和装置
EP2460486A1 (en) * 2010-12-06 2012-06-06 Biosense Webster, Inc. Treatment of atrial fibrillation using high-frequency pacing and ablation of renal nerves
CN102885648A (zh) * 2012-08-29 2013-01-23 中国人民解放军第三军医大学第一附属医院 肾脏去交感神经消融导管系统
CN103271766A (zh) * 2012-08-24 2013-09-04 苏州信迈医疗器械有限公司 一种用于标测和消融位于肾动脉上所分布的肾神经的装置
CN103767787A (zh) * 2014-01-24 2014-05-07 上海魅丽纬叶医疗科技有限公司 用于神经消融的射频消融方法和射频消融系统

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8145316B2 (en) * 2002-04-08 2012-03-27 Ardian, Inc. Methods and apparatus for renal neuromodulation
US9308044B2 (en) * 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US7162303B2 (en) * 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
EP3581224A1 (en) 2008-08-05 2019-12-18 Antares Pharma, Inc. Multiple dosage injector
CN102740925B (zh) 2009-10-12 2015-02-18 科纳医药股份有限公司 神经的能量调节
US8473067B2 (en) * 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
AU2012303696B2 (en) * 2011-08-26 2014-05-29 Symap Medical (Suzhou), Ltd System and method for locating and identifying functional nerves innervating wall of arteries
CN102949176B (zh) * 2011-08-26 2014-11-12 苏州信迈医疗器械有限公司 肾神经消融术中肾神经分布标测方法及用于该方法的导管
US8702619B2 (en) * 2011-08-26 2014-04-22 Symap Holding Limited Mapping sympathetic nerve distribution for renal ablation and catheters for same
US9427579B2 (en) * 2011-09-29 2016-08-30 Pacesetter, Inc. System and method for performing renal denervation verification
US20130158509A1 (en) 2011-12-19 2013-06-20 Paul M. Consigny System, apparatus, and method for denervating an artery
US20130289650A1 (en) * 2012-04-25 2013-10-31 Pacesetter, Inc. Neuromodulation for Hypertension Control
WO2013181137A1 (en) 2012-05-29 2013-12-05 Landy Toth Endoscopic sympathectomy systems and methods
US11357447B2 (en) * 2012-05-31 2022-06-14 Sonivie Ltd. Method and/or apparatus for measuring renal denervation effectiveness
CA2889674C (en) * 2012-11-05 2023-02-28 Autonomix Medical, Inc. Systems, methods, and devices for monitoring and treatment of tissues within and/or through a lumen wall
US9974477B2 (en) * 2013-03-15 2018-05-22 St. Jude Medical, Cardiology Division, Inc. Quantification of renal denervation via alterations in renal blood flow pre/post ablation
CN103519887B (zh) * 2013-10-25 2016-04-20 乐普（北京）医疗器械股份有限公司 一种经皮射频消融去肾交感神经术用系统

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101940815A (zh) * 2004-10-05 2011-01-12 阿迪安公司 肾神经调节的方法和装置
CN101443072A (zh) * 2006-03-06 2009-05-27 阿迪安公司 双侧肾神经调制的方法和装置
EP2460486A1 (en) * 2010-12-06 2012-06-06 Biosense Webster, Inc. Treatment of atrial fibrillation using high-frequency pacing and ablation of renal nerves
CN103271766A (zh) * 2012-08-24 2013-09-04 苏州信迈医疗器械有限公司 一种用于标测和消融位于肾动脉上所分布的肾神经的装置
WO2014029355A1 (en) * 2012-08-24 2014-02-27 Symap Medical (Suzhou) , Ltd Device for mapping and ablating renal nerves distributed on the renal artery
CN102885648A (zh) * 2012-08-29 2013-01-23 中国人民解放军第三军医大学第一附属医院 肾脏去交感神经消融导管系统
CN103767787A (zh) * 2014-01-24 2014-05-07 上海魅丽纬叶医疗科技有限公司 用于神经消融的射频消融方法和射频消融系统

Also Published As

Publication number Publication date
EP3325086B1 (en) 2024-09-11
US20180214212A1 (en) 2018-08-02
CN107847743A (zh) 2018-03-27
US20250152246A1 (en) 2025-05-15
WO2017012907A1 (en) 2017-01-26
US20230157758A1 (en) 2023-05-25
JP2018519963A (ja) 2018-07-26
JP6998295B2 (ja) 2022-01-18
EP3325086A1 (en) 2018-05-30
US12193753B2 (en) 2025-01-14
US11547480B2 (en) 2023-01-10

Similar Documents

Publication Publication Date Title
CN107847743B (zh) 刺激肾神经的系统
US10383685B2 (en) Techniques for use with nerve tissue
CN112704559B (zh) 多极同步肺动脉射频消融导管
US20120150049A1 (en) Impedance measurement to monitor organ perfusion or hemodynamic status
US20170007158A1 (en) Hemodynamic-signal-based electrode-tissue contact detection
RU2015110113A (ru) Система и способ определения места расположения и идентификации функциональных нервов, иннервирующих стенку артерий, и катетеры для них
US20170252101A1 (en) Systems and methods for intraprocedural evaluation of renal denervation
JP7487089B2 (ja) 組み合わされた心臓ペーシング及び不可逆的エレクトロポレーション（ｉｒｅ）処置
US10052257B2 (en) Method and apparatus for stimulative electrotherapy
CN110811605A (zh) 多电极导管中电极表面阻抗的自动调整
JP2021516093A (ja) 応答モニタリング
US20180055410A1 (en) Stimulation and sensing system for meridian condition evaluation
US20180296145A1 (en) System and method for detection of neurotransmitters and proteins in the cardiac system
US10426401B2 (en) Signal characterization to facilitate therapy delivery
JP2021146205A (ja) ペーシングによって誘発された電気的活性化の評価
US9517102B2 (en) Cautery needle for separating and/or penetrating the pericardium
US12383184B2 (en) Late activation of cardiac signals
CN109567802A (zh) 生理信息检测装置及方法
CN118369060A (zh) 心脏静脉消融可视化系统和导管援引加入
US20210268285A1 (en) Electromechanical imaging
EP4171725B1 (en) Treating crt non-responders using cardiac contractility modulation therapy
JP2025020050A (ja) 解剖学的マップをシェービングするための方法及びシステム
HK40051288A (zh) 多极同步肺动脉射频消融导管
HK40051288B (en) Multi-pole synchronous pulmonary artery radiofrequency ablation catheter
JP2015223421A (ja) 神経刺激装置

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant