CN107847447A - 可植入的药物递送组合物及其使用方法 - Google Patents
可植入的药物递送组合物及其使用方法 Download PDFInfo
- Publication number
- CN107847447A CN107847447A CN201680034562.5A CN201680034562A CN107847447A CN 107847447 A CN107847447 A CN 107847447A CN 201680034562 A CN201680034562 A CN 201680034562A CN 107847447 A CN107847447 A CN 107847447A
- Authority
- CN
- China
- Prior art keywords
- composition according
- implantable composition
- matrix
- active agent
- therapeutically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
- A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Botany (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polymers & Plastics (AREA)
- Epoxy Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311411716.6A CN117442742A (zh) | 2015-06-18 | 2016-06-17 | 可植入的药物递送组合物及其使用方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562181707P | 2015-06-18 | 2015-06-18 | |
| US62/181707 | 2015-06-18 | ||
| PCT/US2016/038080 WO2016205652A1 (en) | 2015-06-18 | 2016-06-17 | Implantable drug delivery compositions and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311411716.6A Division CN117442742A (zh) | 2015-06-18 | 2016-06-17 | 可植入的药物递送组合物及其使用方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107847447A true CN107847447A (zh) | 2018-03-27 |
Family
ID=57546385
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311411716.6A Pending CN117442742A (zh) | 2015-06-18 | 2016-06-17 | 可植入的药物递送组合物及其使用方法 |
| CN201680034562.5A Pending CN107847447A (zh) | 2015-06-18 | 2016-06-17 | 可植入的药物递送组合物及其使用方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311411716.6A Pending CN117442742A (zh) | 2015-06-18 | 2016-06-17 | 可植入的药物递送组合物及其使用方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10888530B2 (enExample) |
| EP (1) | EP3310343B1 (enExample) |
| JP (2) | JP6869902B2 (enExample) |
| KR (1) | KR102634491B1 (enExample) |
| CN (2) | CN117442742A (enExample) |
| AU (1) | AU2016280274B2 (enExample) |
| BR (1) | BR112017026746B1 (enExample) |
| CA (1) | CA2989171A1 (enExample) |
| IL (2) | IL287749B2 (enExample) |
| MX (2) | MX382255B (enExample) |
| RU (1) | RU2739033C2 (enExample) |
| SG (1) | SG10202103998RA (enExample) |
| WO (1) | WO2016205652A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113260350A (zh) * | 2018-10-16 | 2021-08-13 | 三角研究所 | 皮下可生物降解储器装置 |
| CN113289075A (zh) * | 2021-04-28 | 2021-08-24 | 珠海横乐医学科技有限公司 | 一种可降解的组合物及其制备方法和应用 |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10842485B2 (en) | 2009-10-15 | 2020-11-24 | Covidien Lp | Brachytherapy buttress |
| US20150231409A1 (en) | 2009-10-15 | 2015-08-20 | Covidien Lp | Buttress brachytherapy and integrated staple line markers for margin identification |
| US10874768B2 (en) * | 2017-01-20 | 2020-12-29 | Covidien Lp | Drug eluting medical device |
| JP7232489B2 (ja) | 2017-05-11 | 2023-03-03 | アルファ タウ メディカル リミテッド | 近接照射療法用装置のためのポリマー被覆 |
| KR102715288B1 (ko) * | 2018-04-02 | 2024-10-11 | 알파 타우 메디컬 리미티드 | 방사성 핵종의 제어된 방출 |
| US11689849B2 (en) | 2018-05-24 | 2023-06-27 | Nureva, Inc. | Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones |
| MX2020012458A (es) | 2018-05-24 | 2021-04-28 | Celanese Eva Performance Polymers Llc | Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular. |
| US11690806B2 (en) | 2018-05-24 | 2023-07-04 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
| CN109908108B (zh) * | 2019-03-15 | 2022-05-03 | 深圳市光远生物材料有限责任公司 | 一种载药纳米复合纤维膜系统及其制备方法和应用 |
| US11596403B2 (en) | 2019-05-08 | 2023-03-07 | Covidien Lp | Surgical stapling device |
| US20200352565A1 (en) * | 2019-05-08 | 2020-11-12 | Covidien Lp | Surgical stapling device |
| US11478245B2 (en) * | 2019-05-08 | 2022-10-25 | Covidien Lp | Surgical stapling device |
| CN114053249B (zh) * | 2020-08-10 | 2023-06-02 | 山东百多安医疗器械股份有限公司 | 一种可治疗全身骨质疏松的可降解载药薄膜及其制备工艺 |
| CN116615264A (zh) | 2020-12-16 | 2023-08-18 | 阿尔法陶医疗有限公司 | 具有增强的β治疗的扩散性α发射体放射疗法 |
| WO2022231930A1 (en) | 2021-04-26 | 2022-11-03 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101091806A (zh) * | 2006-06-20 | 2007-12-26 | 天津市凯迪亚医疗器械有限公司 | 冠脉支架可降解药物缓释涂层 |
| CN101147814A (zh) * | 2007-11-16 | 2008-03-26 | 蔡绪旺 | 一种血管药物支架 |
| CN101522169A (zh) * | 2006-08-02 | 2009-09-02 | 麦迪拉姆医药公司 | 在延长的一段时间里释放活性成分的皮下植入剂 |
| WO2009140131A2 (en) * | 2008-05-13 | 2009-11-19 | The Trustees Of Boston University | Compliant composites for application of drug-eluting coatings to tissue surfaces |
| US20130281977A1 (en) * | 2010-12-30 | 2013-10-24 | Nanyang Technological University | Device for controlled release of a bioactive agent |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX9200038A (es) * | 1991-01-09 | 1992-11-01 | Alza Corp | Dispositivos biodegradables y composiciones para la liberacion por difusion de agentes. |
| DK0797988T3 (da) | 1993-07-19 | 2009-05-11 | Univ British Columbia | Anti-angiogene præparater og fremgangsmåder til anvendelse deraf |
| US5886026A (en) | 1993-07-19 | 1999-03-23 | Angiotech Pharmaceuticals Inc. | Anti-angiogenic compositions and methods of use |
| AU2007254682B2 (en) | 1993-07-19 | 2011-06-02 | Angiotech Pharmaceuticals, Inc. | Anti-angiogenic compositions and methods of use |
| US5626862A (en) | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
| US5759583A (en) * | 1995-08-30 | 1998-06-02 | Syntex (U.S.A.) Inc. | Sustained release poly (lactic/glycolic) matrices |
| US6110484A (en) * | 1998-11-24 | 2000-08-29 | Cohesion Technologies, Inc. | Collagen-polymer matrices with differential biodegradability |
| MXPA01012471A (es) * | 1999-06-04 | 2002-07-30 | Alza Corp | Composiciones de gel implantables y metodo de fabricacion.. |
| KR100446101B1 (ko) * | 2000-12-07 | 2004-08-30 | 주식회사 삼양사 | 수난용성 약물의 서방성 제형 조성물 |
| US20030203000A1 (en) * | 2002-04-24 | 2003-10-30 | Schwarz Marlene C. | Modulation of therapeutic agent release from a polymeric carrier using solvent-based techniques |
| JP2007526009A (ja) * | 2003-06-19 | 2007-09-13 | バスキュラー セラピーズ エルエルシー | 血管閉鎖装具に対する組織反応を調節するための医療装具及び方法 |
| US7531503B2 (en) * | 2005-03-11 | 2009-05-12 | Wake Forest University Health Sciences | Cell scaffold matrices with incorporated therapeutic agents |
| CA2618807C (en) * | 2005-08-12 | 2015-01-06 | University Health Network | Methods and devices for lymphatic targeting |
| US10029034B2 (en) | 2005-12-15 | 2018-07-24 | CARDINAL HEALTH SWITZERLAND 515 GmbH | Drug-eluting articles with improved drug release profiles |
| US8083755B2 (en) * | 2006-06-22 | 2011-12-27 | Novus Scientific Pte. Ltd. | Mesh implant for use in reconstruction of soft tissue defects |
| US8709071B1 (en) * | 2007-09-28 | 2014-04-29 | Abbott Cardiovascular Systems Inc. | Stent with preferential coating |
| CN101264346A (zh) * | 2007-11-27 | 2008-09-17 | 天津百畅医疗器械科技有限公司 | 含有抗凝血磷酸胆碱成份的可降解聚合物血管支架药物涂层 |
| US8629172B2 (en) * | 2008-04-18 | 2014-01-14 | Warsaw Orthopedic, Inc. | Methods and compositions for treating post-operative pain comprising clonidine |
| US20100249924A1 (en) * | 2009-03-27 | 2010-09-30 | Allergan, Inc. | Bioerodible matrix for tissue involvement |
| EP2504472A1 (en) * | 2009-11-24 | 2012-10-03 | Collplant Ltd. | Method of generating collagen fibers |
| EP2900289A1 (en) * | 2012-09-28 | 2015-08-05 | Allergan, Inc. | Porogen compositions, methods of making and uses |
| US9707322B2 (en) * | 2012-12-21 | 2017-07-18 | University Of Connecticut | Gradient porous scaffolds |
| US10682415B2 (en) * | 2013-07-22 | 2020-06-16 | Wisconsin Alumni Research Foundation | Thermogel formulation for combination drug delivery |
-
2016
- 2016-06-17 SG SG10202103998RA patent/SG10202103998RA/en unknown
- 2016-06-17 BR BR112017026746-2A patent/BR112017026746B1/pt active IP Right Grant
- 2016-06-17 WO PCT/US2016/038080 patent/WO2016205652A1/en not_active Ceased
- 2016-06-17 AU AU2016280274A patent/AU2016280274B2/en active Active
- 2016-06-17 IL IL287749A patent/IL287749B2/en unknown
- 2016-06-17 CN CN202311411716.6A patent/CN117442742A/zh active Pending
- 2016-06-17 EP EP16812523.5A patent/EP3310343B1/en active Active
- 2016-06-17 JP JP2017565067A patent/JP6869902B2/ja active Active
- 2016-06-17 CN CN201680034562.5A patent/CN107847447A/zh active Pending
- 2016-06-17 KR KR1020177035884A patent/KR102634491B1/ko active Active
- 2016-06-17 MX MX2017016217A patent/MX382255B/es unknown
- 2016-06-17 RU RU2018101287A patent/RU2739033C2/ru active
- 2016-06-17 CA CA2989171A patent/CA2989171A1/en active Pending
-
2017
- 2017-12-07 IL IL256172A patent/IL256172B/en unknown
- 2017-12-13 MX MX2021004546A patent/MX2021004546A/es unknown
- 2017-12-18 US US15/845,902 patent/US10888530B2/en active Active
-
2019
- 2019-11-11 US US16/679,874 patent/US20200138729A1/en not_active Abandoned
-
2021
- 2021-04-14 JP JP2021068064A patent/JP2021107420A/ja active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101091806A (zh) * | 2006-06-20 | 2007-12-26 | 天津市凯迪亚医疗器械有限公司 | 冠脉支架可降解药物缓释涂层 |
| CN101522169A (zh) * | 2006-08-02 | 2009-09-02 | 麦迪拉姆医药公司 | 在延长的一段时间里释放活性成分的皮下植入剂 |
| CN101147814A (zh) * | 2007-11-16 | 2008-03-26 | 蔡绪旺 | 一种血管药物支架 |
| WO2009140131A2 (en) * | 2008-05-13 | 2009-11-19 | The Trustees Of Boston University | Compliant composites for application of drug-eluting coatings to tissue surfaces |
| US20130281977A1 (en) * | 2010-12-30 | 2013-10-24 | Nanyang Technological University | Device for controlled release of a bioactive agent |
Non-Patent Citations (2)
| Title |
|---|
| 汪多仁: "《合成树脂与工程塑料生产技术》", 31 August 2001, 中国轻工业出版社 * |
| 王璐: "《生物医用纺织品》", 30 November 2011, 中国纺织出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113260350A (zh) * | 2018-10-16 | 2021-08-13 | 三角研究所 | 皮下可生物降解储器装置 |
| CN113289075A (zh) * | 2021-04-28 | 2021-08-24 | 珠海横乐医学科技有限公司 | 一种可降解的组合物及其制备方法和应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2739033C2 (ru) | 2020-12-21 |
| EP3310343B1 (en) | 2023-05-24 |
| JP6869902B2 (ja) | 2021-05-12 |
| CN117442742A (zh) | 2024-01-26 |
| HK1253520A1 (en) | 2019-06-21 |
| RU2018101287A3 (enExample) | 2019-08-19 |
| BR112017026746A2 (pt) | 2018-08-28 |
| US10888530B2 (en) | 2021-01-12 |
| WO2016205652A1 (en) | 2016-12-22 |
| IL287749B1 (en) | 2023-10-01 |
| AU2016280274B2 (en) | 2021-12-02 |
| EP3310343A4 (en) | 2019-02-20 |
| MX2021004546A (es) | 2021-09-10 |
| EP3310343A1 (en) | 2018-04-25 |
| KR102634491B1 (ko) | 2024-02-07 |
| US20200138729A1 (en) | 2020-05-07 |
| KR20180019555A (ko) | 2018-02-26 |
| BR112017026746B1 (pt) | 2023-11-28 |
| IL256172A (en) | 2018-02-28 |
| SG10202103998RA (en) | 2021-05-28 |
| US20180193282A1 (en) | 2018-07-12 |
| MX382255B (es) | 2025-03-13 |
| IL287749B2 (en) | 2024-02-01 |
| JP2021107420A (ja) | 2021-07-29 |
| RU2018101287A (ru) | 2019-07-19 |
| CA2989171A1 (en) | 2016-12-22 |
| JP2018524310A (ja) | 2018-08-30 |
| IL287749A (en) | 2022-01-01 |
| MX2017016217A (es) | 2018-04-24 |
| AU2016280274A1 (en) | 2017-12-07 |
| IL256172B (en) | 2021-12-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107847447A (zh) | 可植入的药物递送组合物及其使用方法 | |
| US8795707B2 (en) | Compliant composites for application of drug-eluting coatings to tissue surfaces | |
| JP6654623B2 (ja) | 切除縁を覆う外科用メッシュ又は外科用バットレスを配置しはり付けるための送達システム | |
| CN108325053B (zh) | 药物洗脱医疗装置 | |
| US20150037375A1 (en) | Doping agents and polymeric compositions thereof for controlled drug delivery | |
| US20220296866A1 (en) | Methods, devices and compositions for local delivery | |
| AU2022390561B2 (en) | Implantable and biodegradable drug delivery devices and methods of use thereof | |
| US20240024644A1 (en) | Tissue penetrating and biodegradable drug delivery devices and methods of use thereof | |
| HK1234640A1 (en) | Delivery system for positioning and affixing surgical mesh or surgical buttress covering a surgical margin | |
| HK1253520B (en) | Implantable drug delivery compositions and methods of use thereof | |
| WO2025029805A2 (en) | Hemostatic compositions and methods |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180327 |
|
| RJ01 | Rejection of invention patent application after publication |