CN107802619A - A kind of concentrate for eye health - Google Patents
A kind of concentrate for eye health Download PDFInfo
- Publication number
- CN107802619A CN107802619A CN201711279921.6A CN201711279921A CN107802619A CN 107802619 A CN107802619 A CN 107802619A CN 201711279921 A CN201711279921 A CN 201711279921A CN 107802619 A CN107802619 A CN 107802619A
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- China
- Prior art keywords
- vitamin
- concentrate
- luteole
- lutein
- content
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 108091008695 photoreceptors Proteins 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 210000003583 retinal pigment epithelium Anatomy 0.000 description 1
- 229940091258 selenium supplement Drugs 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Botany (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The present invention relates to a kind of concentrate for eye health; lutein, luteole and meso-Zeaxanthin are included in the concentration composition formula; then by adding vitamin, trace element and other materials; form concentrate; it is a kind of vision specificity dietetic food, and the concentrate plays a key effect for protection macular pigment to Green Tea Extract, free oxygen.
Description
Technical field
The application is related to dietetic food technical field, more particularly to a kind of concentrate for eye health.
Background technology
Macula lutea is that central fovea of macula is on retina positioned at a pigmentosa region of primate retina Posterior pole
The position most sharp to vision.At present, macular pigment has two kinds of hypothesis to the protection mechanism of retina, when " protection hypothesis ",
Think that carotenoid as antioxidant, removes free radical and free oxygen, so as to limit caused by metabolism and light
Oxygen tension, play a part of protecting retina, second, " optics filtration hypothesis ", it is believed that macular pigment can be with selective absorbing shortwave
Long light, so as to protect photoreceptor and retinal pigment epithelium, and improve eyesight.And age related regards macular degeneration disease
(AMD) it is a kind of main human blindness's disease, often leads to central vision decline during morbidity, make one to blind when serious.Depending on Huang
The spot decline disease incidence of disease is related to the age of people, and the age is bigger, this easier generation of disease.Investigation is found, is only just had in North America
The people of more than 15000000 50 years old suffers from this disease, wherein 1,200,000 people are in a bad way.In U.S.'s population of more than 75 years old, 30% suffers from
Have to a certain degree regard macular degeneration disease, the population for having 23% in addition can suffer from such a disease in subsequent 5 years.Some
Investigation shows, in 55-64 year, 65-74 year and more than 75 years old age bracket crowd, the incidence of disease depending on macular degeneration disease is respectively
16.8%, 25.6% and 42%.
As described above, AMD is a kind of ophthalmology disease that can cause blindness, it forms one often caused by lipid oxidation in eye
Plant fluorescence lipofuscin and cause the generation of drusen, glass-film, CNV.It is generally believed that eyes expose for a long time
The formation of this lipofuscin can be accelerated in the blue light of high-energy.The exact mechanism that AMD is formed at present is not very clear also do not have
Clearly treatment and prevention method, but multiple studies have shown that, AMD formation and carotenoid particularly leaf in development and human eye
The content of flavine and luteole is closely bound up, and the lutein and luteole of volume can delay AMD generation and formation, separately
Outside, internal antioxidant such as vitamin E, vitamin A, selenium, zinc, glutathione also can play inhibitory action to AMD development.
The physiological function of lutein and luteole uniqueness, has caused the increasing interest of people.It is external at present
There is the healthy food and condensed food of the largely natural pigment containing both the above.
Based on the perfect of the understanding and laws and regulations to lutein and luteole eye healthy functions, increasing people from
Also there are many lutein and luteole and treat and prevent fundus macular degeneration (AMD) in the research of thing this respect, in the market
Product in terms of disease.In these researchs or product, the function of lutein, the function about luteole are often concentrated on
Involved by having, but to luteole and the compound use of lutein, then have no report.
The content of the invention
For problem set forth above, the present invention is intended to provide a kind of concentrate for eye health, to solve above-mentioned carry
Go wrong.
Provide a kind of concentrate for eye health in embodiments of the invention, in the concentrate comprising lutein and
Luteole, it can quickly be absorbed by blood, and then supplement macular pigment.
The concentrate includes lutein, luteole and meso-Zeaxanthin, the lutein and luteole
Weight ratio is 3~8:1.
Preferably, the weight ratio of the lutein and luteole is 5:1.
Preferably, the content of the lutein and luteole is respectively 15mg, 3mg, the meso-Zeaxanthin
Content is 10mg.
Wherein, the luteole for according to a conventional method from plant extraction either by chemical synthesis obtain (3R,
3 ' R)-luteole or (3R, 3 ' S)-luteole for being obtained using lutein as raw material by isomerization indexing.The lutein
It is free crystal form or fatty acid ester form with luteole.
Preferably, vitamin and trace element are also included in the concentrate；
Wherein, the vitamin is selected from vitamin B1, vitamin B2, vitamin B3, vitamin B5, vitamin B6, dimension life
One or more in plain B12, vitamin C, vitamine D3, vitamin E；
The content of vitamin described above is respectively：1.5mg、1.7mg、20mg、10mg、10mg、1000mcg、500mg、
2000iu、200iu。
One or more of the trace element in calcium, magnesium, zinc, selenium, copper, manganese, chromium, molybdenum；
Micro- content described above is respectively：250mg、100mg、25mg、70mcg、2mg、2mg、120mcg、
75mcg。
Preferably, folic acid, Biotin, acetylcysteine, acetyl-L-carnitine, ox are also included in the concentrate
Sulfonic acid, Quercetin, Ubidecarenone, astaxanthin, lycopene；
Wherein, folic acid, Biotin, acetylcysteine, acetyl-L-carnitine, taurine, Quercetin, Ubidecarenone,
Astaxanthin, the content of lycopene be respectively 800mcg, 100mcg, 500mg, 500mg, 500mg, 100mg, 50mg,
1000mcg、500mcg。
The technical scheme that embodiments herein provides can include the following benefits：
Lutein, luteole and meso-Zeaxanthin are included in the concentration composition formula of the present invention, then by adding
Add vitamin, trace element and other materials, form concentrate, it is a kind of vision specificity dietetic food, the concentrate pair
Green Tea Extract, free oxygen are played a key effect in protection macular pigment.
Embodiment
Below with reference to embodiment, the present invention will be further described, and embodiments of the invention are merely to illustrate the present invention's
Technical scheme, and the non-limiting present invention.
Provide a kind of concentrate for eye health in embodiments of the invention, in the concentrate comprising lutein and
Luteole, it can quickly be absorbed by blood, and then supplement macular pigment.
The concentrate includes lutein, luteole and meso-Zeaxanthin, the lutein and luteole
Weight ratio is 3~8:1.
Preferably, the weight ratio of the lutein and luteole is 5:1.
Preferably, the content of the lutein and luteole is respectively 15mg, 3mg, the meso-Zeaxanthin
Content is 10mg.
Wherein, the luteole for according to a conventional method from plant extraction either by chemical synthesis obtain (3R,
3 ' R)-luteole or (3R, 3 ' S)-luteole for being obtained using lutein as raw material by isomerization indexing.The lutein
It is free crystal form or fatty acid ester form with luteole.
Luteole mainly has two kinds of forms in eyes, is (3R, 3 ' R) and (3R, 3 ' S) two kinds of isomers respectively,
(3S, 3 ' S) configuration is simply having micro presence depending on macula lutea center.In first two isomers, (3R, 3 ' R) are taken in from the external world
And be transferred to after blood absorption in macula lutea, (3R, 3 ' S) are then different by lutein in the presence of certain enzyme in retina
Structure indexing obtains.So thinking according to current research, luteole is supplemented merely, can only ensure blood or the jade in macula lutea
The content of cream-coloured element, and cannot be guaranteed the supply of internal lutein, and the isomer configuration of luteole and intake in vivo
The configuration of luteole is consistent；Such as simple supplement lutein, leaflet flavine can be converted into meso corn in the middle part of retina
Flavine ((3R, 3 ' S, meso)-luteole), but this conversion can be limited by the horizontal of invertase in individual, it is possible to make
The amount that eyes regard the most central meso luteole of macula lutea is inadequate, so as to have influence on the performance for regarding macular function.Therefore, in order to
Reach a health purpose, human body is preferably while supplement lutein and luteole.
Preferably, vitamin and trace element are also included in the concentrate；
Wherein, the vitamin is selected from vitamin B1, vitamin B2, vitamin B3, vitamin B5, vitamin B6, dimension life
One or more in plain B12, vitamin C, vitamine D3, vitamin E；
The content of vitamin described above is respectively：1.5mg、1.7mg、20mg、10mg、10mg、1000mcg、500mg、
2000iu、200iu。
One or more of the trace element in calcium, magnesium, zinc, selenium, copper, manganese, chromium, molybdenum；
Micro- content described above is respectively：250mg、100mg、25mg、70mcg、2mg、2mg、120mcg、
75mcg。
Preferably, folic acid, Biotin, acetylcysteine, acetyl-L-carnitine, ox are also included in the concentrate
Sulfonic acid, Quercetin, Ubidecarenone, astaxanthin, lycopene；
Wherein, folic acid, Biotin, acetylcysteine, acetyl-L-carnitine, taurine, Quercetin, Ubidecarenone,
Astaxanthin, the content of lycopene be respectively 800mcg, 100mcg, 500mg, 500mg, 500mg, 100mg, 50mg,
1000mcg、500mcg。
When edible, the concentrate of the present invention is taken into a soupspoon, and it mixed with appropriate water, fruit juice, milk etc. equal
Even i.e. edible.
The preferred mode of the application is the foregoing is only, it is all in spirit herein and original not to limit the application
Within then, any modification, equivalent substitution and improvements made etc., it should be included within the protection domain of the application.
Claims (8)
- A kind of 1. concentrate for eye health, it is characterised in that the concentrate include lutein, luteole and Meso-Zeaxanthin, the weight ratio of the lutein and luteole is 3~8:1.
- 2. concentrate according to claim 1, it is characterised in that the weight ratio of the lutein and luteole is 5:1.
- 3. concentrate according to claim 2, it is characterised in that the content of the lutein and luteole is respectively 15mg, 3mg, the content of the meso-Zeaxanthin is 10mg.
- 4. concentrate according to claim 1, it is characterised in that also include vitamin and micro member in the concentrate Element；Wherein, the vitamin be selected from vitamin B1, vitamin B2, vitamin B3, vitamin B5, vitamin B6, vitamin B12, One or more in vitamin C, vitamine D3, vitamin E；It is described trace element selected from calcium, magnesium, zinc, selenium, copper, manganese, chromium, One or more in molybdenum.
- 5. concentrate according to claim 4, it is characterised in that the content of the vitamin is respectively：1.5mg、 1.7mg、20mg、10mg、10mg、1000mcg、500mg、2000iu、200iu。
- 6. concentrate according to claim 4, it is characterised in that the micro- content is respectively：250mg、 100mg、25mg、70mcg、2mg、2mg、120mcg、75mcg。
- 7. concentrate according to claim 1, it is characterised in that in the concentrate also include folic acid, Biotin, Acetylcysteine, acetyl-L-carnitine, taurine, Quercetin, Ubidecarenone, astaxanthin, lycopene.
- 8. concentrate according to claim 7, it is characterised in that the folic acid, Biotin, acetylcysteine, Acetyl-L-carnitine, taurine, Quercetin, Ubidecarenone, astaxanthin, the content of lycopene be respectively 800mcg, 100mcg, 500mg、500mg、500mg、100mg、50mg、1000mcg、500mcg。
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711279921.6A CN107802619A (en) | 2017-12-06 | 2017-12-06 | A kind of concentrate for eye health |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711279921.6A CN107802619A (en) | 2017-12-06 | 2017-12-06 | A kind of concentrate for eye health |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108992544A (en) * | 2018-09-12 | 2018-12-14 | 西安力邦制药有限公司 | A kind of Chinese medicine composition for preventing and treating eye disease |
| CN109222093A (en) * | 2018-08-29 | 2019-01-18 | 华南理工大学 | A kind of water-soluble multi-nutrition additive and preparation and application with eye healthcare function |
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| CN102481011A (en) * | 2009-09-02 | 2012-05-30 | 奥米尼埃克蒂夫健康科技有限公司 | A xanthophyl composition containing macular pigments and a process for its preparation |
| CN103796717A (en) * | 2011-07-07 | 2014-05-14 | 霍华德基金会控股有限公司 | Improvements in or relating to visual performance and/or macular pigmentation |
| CN105146539A (en) * | 2015-09-22 | 2015-12-16 | 哈尔滨宝德生物技术股份有限公司 | Xanthophyll and zeaxanthin containing nutritious food additive and preparing method |
| CN106692259A (en) * | 2015-11-16 | 2017-05-24 | 浙江医药股份有限公司新昌制药厂 | Composition for improving glare stimulation |
| CN106692187A (en) * | 2015-11-16 | 2017-05-24 | 浙江医药股份有限公司新昌制药厂 | Composition for improving visuognosis persistence and protecting eye health |
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2017
- 2017-12-06 CN CN201711279921.6A patent/CN107802619A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102481011A (en) * | 2009-09-02 | 2012-05-30 | 奥米尼埃克蒂夫健康科技有限公司 | A xanthophyl composition containing macular pigments and a process for its preparation |
| CN103796717A (en) * | 2011-07-07 | 2014-05-14 | 霍华德基金会控股有限公司 | Improvements in or relating to visual performance and/or macular pigmentation |
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| CN106692259A (en) * | 2015-11-16 | 2017-05-24 | 浙江医药股份有限公司新昌制药厂 | Composition for improving glare stimulation |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109222093A (en) * | 2018-08-29 | 2019-01-18 | 华南理工大学 | A kind of water-soluble multi-nutrition additive and preparation and application with eye healthcare function |
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Application publication date: 20180316 |