CN107753871A - 一种治疗癫痫的中药组合物 - Google Patents
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Abstract
一种治疗癫痫的中药组合物，该中药是由熟地，当归，紫河车，白芷，全蝎，蜈蚣，僵蚕，广地龙，䗪虫，蝉蜕，蜂房，制南星，制半夏，川郁金，明矾，远志，石菖蒲组成。临床可以用于治疗癫痫。
Description
技术领域
本发明属于中药技术领域，尤其是涉及一种治疗癫痫的中药组合物。
背景技术
本发明涉及的是一种中药配制品，具体的说是一种用于治疗癫痫病的中药组合物。
癫痫病在我国的发病率为0.5％，在临床上十分常见。其主要临床表现为：突然发作倒地，意识丧失，全身抽搐，口吐白沫，两眼向上翻，每次发作持续 1-3分钟。癫痫病对人的危害很大，主要有以下几点：
(1)脑功能的损害：癫痫每发作一次，脑细胞损害一次，长期的癜痫反复发作，患者会智能下降，最后逐渐丧失工作能力，甚至生活能力。(2)意外伤亡：因癜痫是不论时间、地点、环境又不能自我控制突然发作倒地，容易出现摔伤、烫伤、溺水、交通事故。(3)精神创伤：因癫痫病经常发作给患者就业、婚姻、家庭生活均带来影响，因而癫痫患者精神活动较压抑，身心健康受到很大影响，所以对癫痫病应采取及时、有效的办法进行治疗。
目前癫痫病的治疗方法有西药治疗和中药治疗：
一、西药治疗：目前治疗癫痫病的药物很多，以苯妥英钠为代表。其作用原理主要是控制癫痫患者脑内癫痫灶放电，西物作用时间短暂，所以患者需要长期、定时、定量服用一种或多种抗癫痫药物。然而，这类药物副作用较多，长期服用，常出现牙龈增厚、多毛、皮肤粗糙、反应迟钝、精神差、肝功能受损、血液白细胞减少等副作用，因此患者常难以坚持服药。而有相当部分癫痫病人，用药物治疗无效。
二、中药治疗，本品为纯中药制剂，长期服用副作用小，药效迅速、剂量准确、作用可靠。该产品的批量生产具有良好的市场潜力，市场需求。而本产品在我院临床应用多年，疗效显著，深受患者的欢迎。经过临床药理等系统的相关深入研究，条件成熟后将申报中药新药，为我国治疗此病增加新生力量。
发明内容
本发明的目的在于提供一种治疗效果好、有效率高、对人体无毒副作用的治疗癫痫的中药。本发明的目的是这样实现的，根据中医药理论，利用中药独特的药性，采用熟地，当归，紫河车，白芷，全蝎，蜈蚣，僵蚕，广地龙，䗪虫，蝉蜕，蜂房，制南星，制半夏，川郁金，明矾，远志，石菖蒲制成，按照一定的配伍要求，经过加工制成。
制备本发明中药由下述原料药制成：熟地20份，当归20份，紫河车20份，白芷10份，全蝎2份，蜈蚣2份，僵蚕10份，广地龙10份，䗪虫6份，蝉蜕6份，蜂房6份，制南星10份，制半夏10份，川郁金10份，明矾5份，远志10份，石菖蒲10份。
本发明中药使用于2009年至2013年临床观察癫痫症63例患者，临床报告如下：
一般资料
63例患者中，女性33例，男性30例，年龄最小15岁，最大77岁，病程多在2个月到5年，平均年龄43岁。
诊断标准
参照《中药新药治疗痫证临床研究指导原则》：
主症：四肢抽搐有力，伴气高息粗，狂躁不安，舌红苔黄腻，脉滑数。次症：便秘尿赤，口苦而干，平时或发作前情绪急躁，头痛失眠。
治疗方法
处方：熟地20份，当归20份，紫河车20份，白芷10份，全蝎2份，蜈蚣2份，僵蚕10份，广地龙10份，䗪虫6份，蝉蜕6份，蜂房6份，制南星10份，制半夏10份，川郁金10份，明矾5份，远志10份，石菖蒲10份。
服用方法：每日1剂，水煎3次，日分3次服。连服一个月为一个疗程。疗程结束后，再以原方制成丸剂，每次服5份（儿童减半），每日2~3次，六个月为一个疗程，可连服2~3个疗程。
治疗结果：
参照《中医病证诊断疗效标准》：
治愈:癫痫不再发作；
显效:发作频率减少75%；
有效：发作频率减少25%。；
未愈:发作频率减少<25%。
结果：63例患者中，治愈15例(23.8％)，显效28例(44.5％)，有效15例（23.8％），未愈5例(7.9％)，总有效率为92.1％。
典型病例
许某，男，16岁。主因“间断四肢抽搐1月余”，患者因压力过大寐中发生意识模糊，伴四肢抽搐，闭目，口吐痰涎，口中异声，面青，口唇发青，持续1～2分钟后自行缓解，缓解后头晕乏力，遂就诊于总医院，确诊为“癫痫”，予拉莫三嗪口服治疗2周，未见明显好转，以后相继发作4次，症状同前。就诊发现精神可，偶心慌，喘大气，偶口唇发白，自汗盗汗，脾气急躁，好胜心强，记忆力可，纳食一般，寐欠安，入睡难，易醒，呓语，大便质可，一二日一行，小便正常。舌红苔白，脉弦滑。服用本发明治疗癫痫的中药进行治疗，治疗1个疗程后，药后共发作3次，表现同前，持续1分钟左右自行缓解，缓解后乏力，继续服用2个疗程，痊愈，随访半年未发作。
5.2刘某，女，32岁，间歇性头痛、抽搐2年。每年发作3～4次，每次抽风约1～3分钟，发作时口吐白沫伴头痛恶心，牙关紧闭，不省人事，针刺人中穴后清醒。近一月因感冒头痛、发烧输液时扎针疼痛而诱发，角弓反张，口吐白沫，胸闷气短。舌质红，苔薄黄，脉弦滑数。服用本发明治疗癫痫的中药进行治疗，治疗1个疗程后，头痛抽搐逐渐缓解，呕吐痰涎减少，自觉头晕，有时仍头痛，睡眠差，梦多，舌质红，苔薄白，脉滑缓，继续服用3个疗程，痊愈，随访半年未发作。
具体实施方式
下面结合实施例对本发明作进一步的说明，下述该实施例仅用于说明本发明而对本发明没有限制。
实施例，一种治疗癫痫的中药，它是由下述原料药制成：熟地20份，当归20份，紫河车20份，白芷10份，全蝎2份，蜈蚣2份，僵蚕10份，广地龙10份，䗪虫6份，蝉蜕6份，蜂房6份，制南星10份，制半夏10份，川郁金10份，明矾5份，远志10份，石菖蒲10份。
Claims (3)
1.一种治疗癫痫的中药组合物，其特征在于由以下原料药制成，按重量份配比：熟地20份，当归20份，紫河车20份，白芷10份，全蝎2份，蜈蚣2份，僵蚕10份，广地龙10份，䗪虫6份，蝉蜕6份，蜂房6份，制南星10份，制半夏10份，川郁金10份，明矾5份，远志10份，石菖蒲10份。
2.如权利要求1所述的中药组合物，其特征在于，所述中药组合物为药学上可接受的任何剂型。
3.如权利要求2所述的中药组合物，其特征在于，所述剂型为汤剂、丸剂、散剂、冲剂、片剂、胶囊剂或注射剂。
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