CN107744608A - One kind dialysis tube built-in haemodialysis equipment - Google Patents
One kind dialysis tube built-in haemodialysis equipment Download PDFInfo
- Publication number
- CN107744608A CN107744608A CN201711119782.0A CN201711119782A CN107744608A CN 107744608 A CN107744608 A CN 107744608A CN 201711119782 A CN201711119782 A CN 201711119782A CN 107744608 A CN107744608 A CN 107744608A
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- China
- Prior art keywords
- dialysis
- inner tube
- connecting portion
- regulating valve
- haemodialysis equipment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1601—Control or regulation
- A61M1/1603—Regulation parameters
- A61M1/1605—Physical characteristics of the dialysate fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1623—Disposition or location of membranes relative to fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1647—Constructional aspects thereof with flow rate measurement of the dialysis fluid, upstream and downstream of the dialyser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1678—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes intracorporal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
Landscapes
- Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- External Artificial Organs (AREA)
Abstract
The invention discloses one kind dialysis tube built-in haemodialysis equipment, it is related to field of medical device.Dialysis tube built-in haemodialysis equipment provided by the invention includes dialysis tubing and connecting portion, and connecting portion is connected to dialysis tubing；Dialysis tubing includes dialysis outer pipe, dialysis inner tube and dialysis membrane, and dialysis outer pipe is sheathed on dialysis inner tube periphery and space is left between dialysis inner tube, and dialysis membrane wraps and dialysis outer wall of inner tube；Inner tube of dialysing is U-shaped or V-structure, opening are respectively inlet and liquid outlet；Inlet and liquid outlet pass through connecting portion；Connecting portion is provided with regulating valve to open or close inlet and/or liquid outlet and regulation flow velocity.The dialysis tubing partial volume of the dialysis apparatus is small, is placed directly within human body artery and carries out haemodialysis, without blood extract out it is external carry out hemodialysis through machine again, so as on human blood-pressure without influence, safety more more economical than external hemodialysis and wound is small；It can be used for multiple times in the blood vessel with indwelling, be continuously patient and carried out haemodialysis.
Description
Technical field
The present invention relates to field of medical device, especially a kind of dialysis tube built-in haemodialysis equipment.
Background technology
Haemodialysis is the principle flowed using solute by the low side of the high lateral concentration of concentration, by blood and dialysis
Both solution of liquid introduce the dialyzer with hollowfibre semi-permeable membrance simultaneously, allow blood to be located at the one of hollowfibre semi-permeable membrance
Side, dialyzate are located at the opposite side of hollowfibre semi-permeable membrance, make the solution of film both sides by disperse and osmosis, to remove people
In in body blood, small molecule toxins, meanwhile, the electrolyte in blood can also reach balance by osmosis, so as to reach
To the purpose for realizing blood purification.
Haemodialysis is also treatment edema disease, acute and chronic Delayed graft function（Uremia）And acute drugs poisoning and agriculture
The common method of medicine poisoning.China has the up to ten million Chronic Renal Failure Patients to need to remain raw with conventional hemodialysis every year at present
Life, and have the trend increased year by year.
Haemodialysis equipment of the prior art, it usually needs the blood of patient is led in vitro, dialysis is utilized in outside
Defeated time patient's body again after device dialysis.Journey of correcting one's mistakes has the problem of following several respects：（1）Blood is in vitro, is likely to result in trouble
Blood volume is drastically reduced or raised in person's body, causes unstable blood pressure to even result in death；（2）Extracorporal dialysis process is typically only capable to hold
Continue several hours, can not continue, carry out haemodialysis for a long time, smoothly for patient；(3) extracorporal dialysis instrument is huge, it is difficult to transports
It is defeated, it is necessary to patient specially is delivered into dialysate chamber, or huge extracorporal dialysis machine transported it is difficult to patient bedside, increase treatment
Degree；(4) instrument price is expensive, up to hundreds thousand of or even millions of.
The content of the invention
The goal of the invention of the present invention is：For above-mentioned problem, there is provided one kind dialysis tube built-in haemodialysis
Device, the dialysis tubing partial volume of the dialysis apparatus is small, is placed directly within human body artery and carries out haemodialysis, without blood is taken out
Go out it is external carry out hemodialysis through machine again, so as on human blood-pressure without influence, safety more more economical than external hemodialysis and wound is small；Its
It can be in the blood vessel used for multiple times with indwelling, be continuously patient and carry out haemodialysis.
The technical solution adopted by the present invention is as follows：
One kind dialysis tube built-in haemodialysis equipment, it includes dialysis tubing and connecting portion, and the connecting portion is connected to described
Analysis pipe；The dialysis tubing includes dialysis outer pipe, dialysis inner tube and dialysis membrane, and the dialysis outer pipe is sheathed on outside the dialysis inner tube
Space is left between Zhou Bingyu dialysis inner tubes, the dialysis membrane wraps and the dialysis outer wall of inner tube；The dialysis inner tube is U-shaped
Or V-structure, opening are respectively inlet and liquid outlet；The inlet and the liquid outlet pass through the connecting portion；Institute
State connecting portion and be provided with regulating valve to open or close the inlet and/or liquid outlet and regulation flow velocity.
It is provided by the invention dialysis tube built-in haemodialysis equipment operation principle be：Patient is being carried out to dialyse it
Before, puncture is first passed through, is inserted dialysis tubing in human body in femoral artery or radial artery with seal wire or sheath, blood is led to by dialysis outer pipe
Cross, the dialyzate of outside is imported into dialysis inner tube by inlet；Blood and dialyzate are dialysed through dialysis membrane, the superfluous water in blood
Point and small molecule toxins are sustainable infiltrates through in dialyzate, leave blood, and as dialyzate flows out through liquid outlet external, reach
The purpose of dialysis.The dialysis apparatus can import with the dialyzate of outside and guiding device combination has the function that lasting dialysis.
In use, connecting portion in vitro, realizes dialysis tubing and the importing of extracorporal dialysis liquid and the combination of guiding device, meanwhile, regulating valve
For adjusting the flow velocity of dialyzate, regulation dialysis speed, to improve the tolerance of patient.When needing to stop dialysing, it is only necessary to close
Close regulating valve.
The dialysis tube portion of dialysis tube built-in haemodialysis equipment provided by the invention, can basis
The needs of patient, in vivo or so indwelling fortnight, continuous dialysis is on the one hand realized, on the other hand avoid puncturing repeatedly to suffering from
Injury caused by person.
A kind of dialysis tube built-in haemodialysis equipment of the present invention, the regulating valve include feed liquor regulating valve and go out liquid tune
Save valve；Feed liquor regulating valve and/or go out top or bottom that liquid regulating valve is respectively arranged at connecting portion.
A kind of dialysis tube built-in haemodialysis equipment of the present invention, the feed liquor regulating valve include cell body and roller；Institute
Roller is stated to be arranged in the cell body；The cell body is obliquely installed, and two side is provided with roller rolling guide, and bottom is provided with bullet
Property leather strap；The inlet is arranged at the lower section in the middle part of the elastic leather strap.
By adopting the above-described technical solution, the flow of inlet and/or liquid outlet can be adjusted for regulating valve, also
Inlet and/or liquid outlet can be closed to stop dialysing.The regulation of regulating valve is by adjusting pair of rollers inlet and/or going out liquid
The squish area of mouth is realized.The elastic leather strap set between roller and inlet and/or liquid outlet has cushioning effect, avoids rolling
Wheel destroys inlet and/or liquid outlet.
A kind of dialysis tube built-in haemodialysis equipment of the present invention, the dialysis inner tube spiral are set.
By adopting the above-described technical solution, the dialysis inner tube that spiral is set can be effectively increased dialysis area, improve saturating
Analyse efficiency.
A kind of dialysis tube built-in haemodialysis equipment of the present invention, is provided between the connecting portion and the dialysis tubing
Fixed part, the fixed part include fixed seat and the fin being symmetricly set on for a pair in fixed seat.
As a result of above-mentioned technical side, the fin of fixed part can be effectively increased for fixed area, make device easy
It is fixed, dialysis tubing is avoided in the harm that intra-arterial is mobile or slides.
A kind of dialysis tube built-in haemodialysis equipment of the present invention, the dialysis outer pipe is engraved structure.
By adopting the above-described technical solution, the engraved structure of dialysis outer pipe, easily facilitates blood and enters in dialysis outer pipe
Dialysis is carried out with the dialyzate in dialysis inner tube to exchange.
A kind of dialysis tube built-in haemodialysis equipment of the present invention, the one end of the dialysis outer pipe away from inlet is set
There is rigid plastics head.
By adopting the above-described technical solution, dialysis tubing insertion artery is being to play a part of to break through by rigid plastics head, prevent
Only tube head is excessively soft, inserts and does not enter blood vessel.Rigid plastics can use the high material of biocompatibility in the prior art, as gathered in oneself
Ester and Terlux.
A kind of dialysis tube built-in haemodialysis equipment of the present invention, a diameter of 0.5-2mm of the dialysis inner tube, pipe range
For 200-300mm.
A kind of dialysis tube built-in haemodialysis equipment of the present invention, a diameter of 3-5mm of the dialysis outer pipe, pipe range are
150-300mm。
In summary, by adopting the above-described technical solution, the beneficial effects of the invention are as follows：
It is provided by the invention dialysis tube built-in haemodialysis equipment including the use of when be placed in internal dialysis tubing and external company
Socket part；It is placed in internal dialysis tubing and is divided into dialysis inner tube and dialysis outer pipe, dialysis membrane is wrapped with being realized in dialysis inner tube in dialysis
The Dialysis between the dialyzate in blood and dialysis inner tube in pipe；Can be according to the needs of patient, indwelling two in vivo
In or so individual week, lasting haemodialysis function is provided for patient；External connecting portion on the one hand realize the dialysis apparatus with it is outer
The combination of part device, on the other hand set regulating valve to go out the speed of liquid to adjust feed liquor, and terminate dialysis.In addition, also set
It is equipped with fixed part dialysis tubing is fixed, avoids dialysis tubing mobile or slide.Use dialysis tube built-in provided by the invention
When haemodialysis equipment carries out haemodialysis, dialysis tubing, which is placed directly within human body artery, carries out haemodialysis, without blood is taken out
Go out it is external carry out hemodialysis through machine again, so as on human blood-pressure without influence, it is more more economical than external hemodialysis, and dialysis tubing can be
Indwelling for a period of time, avoids carrying out invasive injury to patient repeatedly in human body.
Brief description of the drawings
Examples of the present invention will be described by way of reference to the accompanying drawings, wherein：
Fig. 1 is the schematic diagram that the present invention provides dialysis tube built-in haemodialysis equipment；
Fig. 2 is the schematic diagram of dialysis tubing；
Fig. 3 is the diagrammatic cross-section of liquid feed valve.
In figure, 1 is dialysis tubing, and 11 be dialysis outer pipe, and 12 dialysis inner tubes, 121 be inlet, and 122 be liquid outlet, and 2 be company
Socket part, 21 be cell body, and 22 be roller, and 23 be elastic leather strap, and 3 be fixed part, and 31 be fixed seat, and 32 be fin.
Embodiment
All features disclosed in this specification, or disclosed all methods or during the step of, except mutually exclusive
Feature and/or step beyond, can combine in any way.
This specification（Including any accessory claim, summary）Disclosed in any feature, unless specifically stated otherwise,
Replaced by other equivalent or with similar purpose alternative features.I.e., unless specifically stated otherwise, each feature is a series of
An example in equivalent or similar characteristics.
Such as Fig. 1, the present embodiment provides a kind of dialysis tube built-in haemodialysis equipment, and it includes dialysis tubing 1, is connected to
Analyse the connecting portion 2 of pipe 1, the fixed part 3 being arranged between dialysis tubing 1 and connecting portion 2.
Dialysis tubing 1 includes dialysis outer pipe 11, dialysis inner tube 12 and dialysis membrane.Dialysis outer pipe 11 is sheathed on dialysis inner tube 12
Periphery, space is left between dialysis outer pipe 11 and dialysis inner tube 12 in order to which blood circulation, the hollow out of dialysis outer pipe 11 are set, so as to
In the space that blood enters dialysis outer pipe 11 between inner tube 12 of dialysing.Dialysis membrane wrap with dialysis inner tube 12 outer wall on, can
Think that dialysis inner tube 12 plays support dialysis membrane or moulding for dialysis membrane.Circulation dialyzate, dialysis tubing in inner tube 12 of dialysing
12 U-shaped or V-structures, that is, two openings of inner tube 12 of dialysing are positioned at same one end of dialysis outer pipe 11, one of opening
Inlet 121, another opening is liquid outlet 122.
Connecting portion 2 is connected to dialysis tubing 1, and dialysis inner tube 12 runs through connecting portion 1, and inlet 121 and liquid outlet 122 distinguish position
In connecting portion, it is easy to dialysis tubing 1 and outside connection.Connecting portion 2, which is provided with, feed liquor regulating valve and goes out liquid regulating valve, to open or
Inlet 121 and/or liquid outlet 122 are closed, or adjusts feed liquor and/or goes out liquid speed degree.Regulating valve may be provided at connecting portion
Top or bottom.In the present embodiment, feed liquor regulating valve and go out the top that liquid regulating valve is symmetricly set on connecting portion, feed liquor regulating valve
Including cell body 21 and roller 22, roller 22 is arranged in cell body 21, and the top droop of cell body 21 is set, and higher end is low, and two
Side wall sets the guide rail for being provided with the rolling of roller 22, and the lower section of roller 22 sets flexible leather strap 23, and inlet 121 is located at elastic skin
The lower section of bar 23.Roller 22 extrudes elastic leather strap 23 when being rolled on guide rail from higher one section of cell body 21 to relatively low one section
The inlet 121 of lower section, in diverse location, squish area is different, so as to realize the fluid velocity of regulation inlet 121 or open
Close.Go out liquid regulating valve to be symmetrical arranged with feed liquor regulating valve, structure is identical, repeats no more herein.
In the present embodiment, a diameter of 3-5mm of dialysis outer pipe 11, pipe range 150-300mm.Dialyse inner tube 12 it is a diameter of
0.5-2mm, pipe range 200-300mm.
Fixed part 3 is arranged between dialysis tubing 1 and connecting portion 2, for fixing dialysis tubing 1.Fixed part 3 includes fixed seat 31
With a pair of fins 32 being symmetricly set in fixed seat 31, fin 32 is used to increase fixed-area, and fin 32 can be relative to fixation
Seat 31 rotates, and easily facilitates fixation.
The method that dialysis tubing 1 is placed in human body artery in the present invention is that prior art is no longer described in detail herein.
The use process of dialysis tube built-in haemodialysis equipment provided by the invention is as follows：
Before being dialysed to patient, puncture is first passed through, dialysis tubing 1 is inserted into femoral artery or oar in human body with seal wire or sheath
In artery, then fixed part 3 is fixed on a patient body with adhesive tape with one, by the inlet 121 for inner tube 12 of dialysing and outside
Feeding device connects, and the liquid outlet 122 for inner tube 12 of dialysing is connected with outside liquid discharge device, the dialysis that outside feeding device provides
Liquid enters dialysis inner tube 12 and dialysed with the blood in dialysis outer pipe 11 through dialysis membrane, excessive moisture and small molecule toxins in blood
It is sustainable to infiltrate through in dialyzate, leave blood, and as dialyzate through liquid outlet 122 flows out the external purpose for reaching dialysis.
During dialysis, the flow velocity of valve regulation dialyzate can be adjusted to adjust dialysis speed by adjusting feed liquor regulating valve and/or going out liquid.
After dialysis terminates, be first shut off feed liquor regulating valve and going out liquid regulating valve, be then turned off inlet 121 and liquid outlet 122 with it is outer
The connection of portion's feeding device and liquid discharge device.Dialysis tubing 1 can be according to the needs of patient, and indwelling fortnight is left in vivo
It is right.
The invention is not limited in foregoing embodiment.The present invention, which expands to, any in this manual to be disclosed
New feature or any new combination, and disclose any new method or process the step of or any new combination.
Claims (9)
1. one kind dialysis tube built-in haemodialysis equipment, it is characterised in that it includes dialysis tubing and connecting portion, the connecting portion
It is connected to the dialysis tubing；The dialysis tubing includes dialysis outer pipe, dialysis inner tube and dialysis membrane, the dialysis outer pipe and is sheathed on institute
State dialysis inner tube periphery and leave space between dialysis inner tube, the dialysis membrane wraps and the dialysis outer wall of inner tube；It is described
Inner tube of dialysing is U-shaped or V-structure, opening are respectively inlet and liquid outlet；The inlet and the liquid outlet pass through
The connecting portion；The connecting portion is provided with regulating valve and flowed with opening or closing the inlet and/or liquid outlet and regulation
Speed.
2. it is according to claim 1 dialysis tube built-in haemodialysis equipment, it is characterised in that the regulating valve include into
Liquid regulating valve and go out liquid regulating valve；Feed liquor regulating valve and/or go out top or bottom that liquid regulating valve is respectively arranged at connecting portion.
3. dialysis tube built-in haemodialysis equipment according to claim 2, it is characterised in that the feed liquor regulating valve bag
Include cell body and roller；The roller is arranged in the cell body；The cell body is obliquely installed, and two side is provided with roller rolling and led
Rail, bottom set flexible leather strap；The inlet is arranged at the lower section in the middle part of the elastic leather strap.
4. dialysis tube built-in haemodialysis equipment according to claim 1, it is characterised in that the dialysis inner tube spiral
Set.
5. it is according to claim 1 dialysis tube built-in haemodialysis equipment, it is characterised in that the connecting portion with it is described
Fixed part is provided between dialysis tubing, the fixed part includes fixed seat and the fin being symmetricly set on for a pair in fixed seat.
6. dialysis tube built-in hemodialysis system according to claim 1, it is characterised in that the dialysis outer pipe is to engrave
Hollow structure.
7. dialysis tube built-in haemodialysis equipment according to claim 1, it is characterised in that the dialysis outer pipe is remote
One end of inlet is provided with rigid plastics head.
8. dialysis tube built-in haemodialysis equipment according to claim 1, it is characterised in that the straight of inner tube of dialysing
Footpath is 0.5-2mm, pipe range 200-300mm.
9. it is according to claim 1 dialysis tube built-in haemodialysis equipment, it is characterised in that the dialysis outer pipe it is straight
Footpath is 3-5mm, pipe range 150-300mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711119782.0A CN107744608A (en) | 2017-11-14 | 2017-11-14 | One kind dialysis tube built-in haemodialysis equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711119782.0A CN107744608A (en) | 2017-11-14 | 2017-11-14 | One kind dialysis tube built-in haemodialysis equipment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107744608A true CN107744608A (en) | 2018-03-02 |
Family
ID=61251335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711119782.0A Withdrawn CN107744608A (en) | 2017-11-14 | 2017-11-14 | One kind dialysis tube built-in haemodialysis equipment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107744608A (en) |
-
2017
- 2017-11-14 CN CN201711119782.0A patent/CN107744608A/en not_active Withdrawn
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|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20180302 |
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| WW01 | Invention patent application withdrawn after publication |