CN107714947A - It is a kind of to be used to treat instant particles as Chinese medicine of malakoplakis of bladder and preparation method thereof - Google Patents

Abstract

The invention discloses a kind of instant particles as Chinese medicine for being used to treat malakoplakis of bladder and preparation method thereof, belong to the field of Chinese medicines.The raw material of effective ingredient of the present invention forms：Cup chrysanthemum, cuneate lespedeza herb with root, Chinese yam, bunge bedstraw herb, cowpea, horse hail, the bighead atractylodes rhizome, juglandis,semen, the red sage root, dindygulen peperomia herb, unpleasant swallowwort herb, radix glycyrrhizae, Radix Codonopsis, variegated leaf orchid, fiveleaf akebia fruit, wilsonii, the root of herbaceous peony, Common Achyranthes Herb, intermediate peashrub root, weak ixeris herb, centella, smallflower beggarticks herb, road blocking tiger, the fruit of Chinese magnoliavine.The present invention is mutually fitted mutually auxiliary from the property of medicine of medicinal material, suited the remedy to the case for the cause of disease, have the effect of strengthening spleen, tonifying kidney, soft liver is soothing the liver, supplementing qi and nourishing yin, clearing heat and detoxicating, promoting blood circulation and removing blood stasis, anti-inflammation hemostasia, dispersing swelling and dissipating binds, resolving sputum diuresis, good absorbing effect, it is evident in efficacy, have no toxic side effect and clinical adverse, it is higher to malakoplakis of bladder cure rate according to clinical verification.

Description

It is a kind of to be used to treat instant particles as Chinese medicine of malakoplakis of bladder and preparation method thereof

Technical field

The present invention relates to the field of Chinese medicines, more particularly to a kind of instant particles as Chinese medicine and its preparation side for being used to treat malakoplakis of bladder Method.

Background technology

Malakoplakis of bladder is a kind of rare disease, is a kind of not clear special inflammatory reaction of reason, malakoplakis of bladder Patient has gross hematuria and urinary tract infection symptom more, it is considered that is a kind of special reaction to infection, possibly due to host Immune response is disorderly or macrophage lysosome activity caused by abnormal, this disease easily come across immuuoeorapromised host or kidney transplant Patient.This disease is not usually required to operative treatment, typically quinolione class antimicrobial such as levofloxacin tablet need to be used to treat, may be used also To be treated with a little Bethanechol Chlorides, you can gradually take a turn for the better, but generally course for the treatment of length, easily recurrence.

For malakoplakis of bladder in traditional Chinese medicine mostly with the characteristics of asthenia in origin and asthenia in superficiality, this void is mostly spleen kidney qi deficiency, stagnation of liver qi etc., Mark is mostly damp and hot, scorchingly hot in fact, phlegm is turbid, hemostasis is trouble.Thus the present invention suits the remedy to the case according to the cause of disease, is dredged with strengthening spleen, tonifying kidney, soft liver Based on liver, supplementing qi and nourishing yin, and with clearing heat and detoxicating, promoting blood circulation and removing blood stasis, anti-inflammation hemostasia, dispersing swelling and dissipating binds, resolving sputum diuresis, human body can be improved and exempted from Epidemic disease power, anti-inflammation, the reparation and regeneration of promotion organization, effective symptom management development, equilibrium between yin and yang is adjusted, reaches complete health Multiple purpose, good absorbing effect is evident in efficacy, has no toxic side effect and clinical adverse, according to clinical verification to malakoplakis of bladder Cure rate is higher.

The content of the invention

The invention provides a kind of instant particles as Chinese medicine for being used to treat malakoplakis of bladder and preparation method thereof, there is invigorating the spleen to mend Kidney, soft liver is soothing the liver, supplementing qi and nourishing yin, clearing heat and detoxicating, promoting blood circulation and removing blood stasis, anti-inflammation hemostasia, dispersing swelling and dissipating binds, resolving sputum diuresis the effect of, cure the disease Ask source to treat both principal and secondary aspect of disease, the effect of fine is respectively provided with to malakoplakis of bladder caused by a variety of causes.

To achieve the above object, technical scheme is implemented as follows：

A kind of instant particles as Chinese medicine for treating malakoplakis of bladder, the raw material composition and parts by weight that the effective ingredient is made are：

Cup 25~40 parts of chrysanthemum, 20~30 parts of cuneate lespedeza herb with root, 15~30 parts of Chinese yam, 15~30 parts of bunge bedstraw herb,

15~30 parts of cowpea, 10~25 parts of horse hail, 10~25 parts of the bighead atractylodes rhizome, 10~25 parts of juglandis,semen,

9~20 parts of the red sage root, 9~20 parts of dindygulen peperomia herb, 9~15 parts of unpleasant swallowwort herb, 9~15 parts of radix glycyrrhizae,

6~12 parts of Radix Codonopsis, 6~12 parts of variegated leaf orchid, 5~10 parts of fiveleaf akebia fruit, 5~10 parts of wilsonii,

5~10 parts of the root of herbaceous peony, 4~9 parts of Common Achyranthes Herb, 4~9 parts of intermediate peashrub root, 4~9 parts of weak ixeris herb,

3~7 parts of centella, 3~7 parts of smallflower beggarticks herb, 2~6 parts of road blocking tiger, 1~3 part of the fruit of Chinese magnoliavine.

Be made the effective ingredient raw material composition and parts by weight be：

Cup 30~36 parts of chrysanthemum, 23~28 parts of cuneate lespedeza herb with root, 18~25 parts of Chinese yam, 18~25 parts of bunge bedstraw herb,

18~24 parts of cowpea, 15~20 parts of horse hail, 15~20 parts of the bighead atractylodes rhizome, 15~20 parts of juglandis,semen,

12~18 parts of the red sage root, 12~16 parts of dindygulen peperomia herb, 11~13 parts of unpleasant swallowwort herb, 11~13 parts of radix glycyrrhizae,

8~10 parts of Radix Codonopsis, 8~10 parts of variegated leaf orchid, 6~9 parts of fiveleaf akebia fruit, 6~8 parts of wilsonii,

6~8 parts of the root of herbaceous peony, 5~7 parts of Common Achyranthes Herb, 5~7 parts of intermediate peashrub root, 5~7 parts of weak ixeris herb,

4~6 parts of centella, 4~6 parts of smallflower beggarticks herb, 3~5 parts of road blocking tiger, 1~2 part of the fruit of Chinese magnoliavine.

Be made the effective ingredient raw material composition and parts by weight be：

Cup 34 parts of chrysanthemum, 26 parts of cuneate lespedeza herb with root, 23 parts of Chinese yam, 22 parts of bunge bedstraw herb,

22 parts of cowpea, 18 parts of horse hail, 18 parts of the bighead atractylodes rhizome, 18 parts of juglandis,semen,

16 parts of the red sage root, 14 parts of dindygulen peperomia herb, 12 parts of unpleasant swallowwort herb, 12 parts of radix glycyrrhizae,

9 parts of Radix Codonopsis, variegated leaf are blue 9 parts, 8 parts of fiveleaf akebia fruit, 7 parts of wilsonii,

7 parts of the root of herbaceous peony, 6 parts of Common Achyranthes Herb, 6 parts of intermediate peashrub root, 6 parts of weak ixeris herb,

5 parts of centella, 5 parts of smallflower beggarticks herb, 4 parts of road blocking tiger, 1 part of the fruit of Chinese magnoliavine.

A kind of preparation method for the instant particles as Chinese medicine for treating malakoplakis of bladder, is comprised the following steps that：

（1）By cup chrysanthemum, cuneate lespedeza herb with root, Chinese yam, bunge bedstraw herb, cowpea, horse hail, the bighead atractylodes rhizome, juglandis,semen, unpleasant swallowwort herb, Common Achyranthes Herb, caragana microphylla Root, weak ixeris herb, centella, smallflower beggarticks herb, road blocking tiger clean dry after be well mixed, be put into container, in a reservoir add 6~8 The water of amount again, heating are boiled 2~3 hours, and immersion liquid is taken after cooling；The water of 4~6 times of amounts, heating are added in the remaining dregs of a decoction Boil 1~2 hour, immersion liquid is taken after cooling；Merge gained immersion liquid twice, heating, be concentrated by evaporation as relative density 1.15~1.25 Thick paste, it is standby；

（2）Danshen Tablets are taken, add yellow rice wine to mix thoroughly, vexed profit is put in pot, fried with slow fire to saturating, and taking-up is cooled, and crushing is ground, and crosses 100 mesh Dusting cover, fine powder is obtained, it is standby；

（3）Dindygulen peperomia herb, variegated leaf orchid, fiveleaf akebia fruit, wilsonii, the fruit of Chinese magnoliavine are put into container, add the shao-hsing rice wine of 3~5 times of amounts, Cooled after boiling, continue immersion 3~5 hours, take immersion liquid；The shao-hsing rice wine of 2~4 times of amounts is added in the remaining dregs of a decoction, is boiled Cooled after boiling, continue immersion 2~4 hours, take immersion liquid；Merge gained immersion liquid twice, it is relative density 1.10 to add steaming to be concentrated by evaporation ~1.20 thick paste, it is standby；

（4）Net licorice tablet is taken, adds cooked honey and a little boiling water, it is slightly vexed after mixing thoroughly, put in frying container, slow fire is fried to depth Yellow, take out, cool when tack-free, crushing is ground, and is crossed 100 mesh dusting covers, is obtained fine powder, standby；

（5）Wheat bran is placed in the pot of heating, to pot on when playing cigarette, add Radix Codonopsis piece, stir to buff, taking-up and weed out bran Skin, cool, crushing is ground, and is crossed 100 mesh dusting covers, is obtained fine powder, standby；

（6）Take root of herbaceous peony piece, spray yellow rice wine is mixed thoroughly, and vexed profit is put in pot to saturating, is fried with slow fire slightly yellow to surface, and taking-up cools, powder It is broken to grind, 100 mesh dusting covers are crossed, obtain fine powder, it is standby；

（7）By step（1）, step（3）The thick paste of gained, with step（2）, step（4）, step（5）, step（6）Middle gained Fine powder mixes, and adds auxiliary material sucrose and dextrin to be well mixed and particle is made, dries, after whole grain, be packaged into every bag of 8g instant particles as Chinese medicine.

The property of medicine of Chinese medicine used in the present invention is as follows：

Cup chrysanthemum：Bitter, it is cool in nature.Clearing heat and detoxicating, anti-inflammation hemostasia, dehumidify diuresis, desinsection.Cure mainly acute gastroenteritis, heatstroke, bladder Inflammation, urethritis, sphagitis, stomatitis, spit blood, bleeding from five sense organs or subcutaneous tissue.

Cuneate lespedeza herb with root：It is bitter, puckery, cool in nature.Return lung；Liver；Kidney channel.The puckery essence of kidney tonifying；Invigorating spleen to remove dampness；Preventing phlegm from forming and stopping coughing；It is clearing heat and detoxicating. Cure mainly kidney deficiency；Seminal emission；The enuresis；Frequent micturition；Gonorrhoea；Under band；Diarrhea；Dysentery；Oedema；Infantile malnutrition；Cough and asthma；Traumatic injury； Red eye, swell pain；Ulcerative carbuncle pyogenic infections；Insect-bite.《Traditional Chinese Medicine in Sichuan will》：Control the weak enuresis, man's gonorrhoea, woman leukorrhea, deficiency of Yin gas It is weak, promoting lactation, treat infantile malnutrition due to digestive disturbances or intestinalparasites disease.Modern study proves：Cuneate lespedeza herb with root has cough-relieving, eliminating the phlegm, relievingd asthma, the effect such as antibacterial, has choosing to uterus Select heat effect.

Chinese yam：It is sweet；It is mild-natured.Enter spleen；Lung；Kidney channel.Tonifying spleen nourishing the stomach；Engender liquid and benefic lung；The puckery essence of kidney tonifying.Cure mainly spleen eating less； Endless diarrhea；The deficiency syndrome of the lung is breathed with cough；Emission due to the kidney deficiency；Under band；Frequent micturition；Abnormal heat is quenched one's thirst.《Compendium of Materia Medica》Carry：" strengthening the spleen and tonifying the lung, long will peace God, control dry, kidney qi loss of lassitude, poor appetite, Lung Qi deficiency etc.." modern medicine study shows that Chinese yam is rich in 18 kinds of amino Acid and more than 10 plants micro- and other mineral matters, Human Lipid Metabolism exception and artery sclerosis can be prevented, to safeguarding pancreas islet Plain normal function also has certain effect, can strengthen body immunity, and invigorating heart is calmed the nerves, peaceful cough Dingchuan, anti-aging.

Bunge bedstraw herb：It is sweet；It is bitter；It is mild-natured.Return liver；The spleen channel.Heat-clearing；Diuresis；Removing toxic substances；Detumescence.Cure mainly：Urinary tract infections；Cancerous swelling； Leukorrhea with reddish discharge；Dysentery；Carbuncle swells；Traumatic injury；Hemoptysis；Women's leukorrhea with reddish discharge；Infantile malnutrition；Carbuncle swells serious case of furuncle；Venomous snake bite.《River Western herbal medicine》：It is clearing heat and detoxicating, swelling and pain relieving, tonneau urine.

Cowpea：It is sweet, it is mild-natured.Returns spleen, kidney channel.Strengthening spleen, tonifying kidney.Weakness of the spleen and the stomach, rush down dysentery is controlled, tells inverse, is quenched one's thirst, is passed out semen, in vain Band, gonorrhoea, frequent urination.《Detailed outline》：" QI invigorating in reason, tonifying kidney and promoting digestion, and the five internal organs, battalion is adjusted to defend, production of sperm marrow.Only quench one's thirst, tell it is inverse, Dysentery is let out, urine number, solves the big poison of mouse."

Horse hail：It is sweet；It is bitter；It is cool in nature.Return lung；Liver；The spleen channel.It is clearing heat and detoxicating；Dispersing swelling and dissipating binds；Resolving sputum diuresis.Cure mainly ulcerative carbuncle furuncle； Subcutaneous nodule scrofula；Abscess of throat；Mumps；Urolithiasis；Difficult urination；Skin eczema；Hot eyes jaundice；Hemorrhoid complicated by anal fistula；Prolapse of the anus；Traumatism and bleeding；Poison Snake bite.Guangzhou army《Conventional Chinese herbal medicine handbook》：Detumescence and drawing out poison, eliminating phlegm dissipating bond, clearing liver Li Shui.Ulcerative carbuncle furuncle is controlled, skin is wet Rash, abscess of throat, parotitis, urinary tract infections, calculus, acute conjunctivitis, infantile malnutrition.

The bighead atractylodes rhizome：Bitter；It is sweet；It is warm-natured.Returns spleen；Stomach.Strengthening the spleen and replenishing qi；Eliminate dampness and have diuretic effect；Hidroschesis；It is antiabortive.Cure mainly deficiency-weakness of spleen-QI； Spiritlessness and weakness；Deficiency of food abdominal distension；Big loose stool is thin；Fluid retention stagnating in the interior；Difficult urination；Oedema；Phlegmatic vertigo；Arthritis with fixed pain caused by dampness is ached；Spontaneous perspiration due to deficiency of vital energy； Fetal irritability.《This is through meeting original》Carry：" art, it is raw with there is dehumidifying dry, the dissolving phlegm Li Shui of benefit, wind-cold-dampness arthralgia is controlled, dead flesh convulsion subcutaneous ulcer, dissipates waist navel Between blood, and chong channel is disease, the work(of urgency in inverse gas；Make it is ripe, have with middle tonifying Qi, slake thirst and help produce saliva, hidroschesis enters diet except heat, it is antiabortive it Effect." modern medicine study confirms, the bighead atractylodes rhizome has diuresis, hypoglycemic, strong, anticoagulation, antitumor, antibacterial, promotes hematopoiesis and egg The effect of white matter synthesis.

Juglandis,semen：It is sweet；It is puckery；It is warm-natured.Return kidney；Liver；Lung channel.Invigorate the kidney and stop nocturnal emission；Warm lung Dingchuan；Relax bowel.Cure mainly：Pain in the back Flaccidity of lower limbs；Frequent micturition；The enuresis；Impotence；Seminal emission；Chronic cough syndrome characterized by dyspnea；Dry constipation of intestines；Urolithiasis and sore scrofula.《Records of Tradition Chinese and Western Medicine in Combination》：Recklessly Peach, be nourishing liver and kidney, strong muscles and bones key medicines, thus it is kind control Low Back Pain and have a pain in the leg, all arthralgia and myalgias.For its can kidney tonifying, therefore can permanent tooth Tooth, black beard and hair, control consumptive disease asthma and cough, gas does not return member, the lower burnt cold of insufficiency type, frequent urination, and woman is collapsed with all cards.Its property and can heavily fortified point that disappears is opened The stasis of blood, trusted subordinate's pain is controlled, sand leaching, urolithiasis are made to ache, and kidney loses the water that can not filter, difficult urination.Modern medicine proves：Phosphorus in juglandis,semen Fat, there is fine health-care effect to cranial nerve.Walnut oil contains unrighted acid, there is the effect of preventing and treating artery sclerosis.Juglandis,semen In increasingly reduced containing the indispensable trace element of human body, human body zinc, manganese content in aging course such as zinc, manganese, chromium, chromium has Promote glucose utilization, cholesterol metabolic and the cardiovascular function of protection.The antitussive and antiasthmatic of juglandis,semen acts on also fairly obvious, the winter It is season, splendid to chronic bronchitis and asthmatics' curative effect.

The red sage root：Bitter；Cold nature；It is nontoxic.Enter the heart；Liver Channel.Promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness that clears away heart-fire, cool blood to disappear carbuncle. For chest impediment and cardialgia, gastral cavity abdomen hypochondriac pain, the accumulation of lump in the abdomen lump in the abdomen, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhoea Amenorrhea, sore swell and ache curative. 《This warp》Carry：" main trusted subordinate's perverse trend, borborygmus is faint such as to leak water, fever and chills accumulation；Broken disease removes lump in the abdomen, only dysphoria, QI invigorating." modern medicine grinds Study carefully confirmation, the red sage root has anti-inflammatory analgetic, coronary artery dilator, improves myocardial ischemia situation, hypotensive, hypoglycemic, reducing blood lipid, guarantor The effect of the reparation and regeneration of liver, antibacterial and promotion organization, the red sage root also have anti-platelet aggregation, reduce blood viscosity and regulation The function of inside and outside blood coagulation system.

Dindygulen peperomia herb：Acrid flavour；It is cool in nature.Return lung；Spleen；Liver；Kidney channel.It is clearing heat and detoxicating；Blood stasis-eliminating and stagnation-dissipating；Inducing diuresis for removing edema.Cure mainly lung heat Cough and asthma；Measles；Sore；Cancerous swelling；Burn and scald；Traumatic injury；Nephritic dropsy.《Simao, Yunnan Chinese herbal medicine selects》：It is clearing heat and detoxicating, detumescence The stasis of blood is dissipated, relieves pain Li Shui.Traumatic injury is controlled, scalds burn, carbuncle swells boil, nephritic dropsy, pulmonary tuberculosis, asthma, tracheobronchitis, lung Heat cough.

Unpleasant swallowwort herb：Acrid flavour, it is mild-natured.Kidney tonifying, invigorating the spleen, detoxification.Control consumptive disease to cough long, edema, leukorrhea, irregular menstruation, scrofula, sore Scabies.《Shaanxi Chinese herbal medicine》：" enriching yin and nourishing kidney, strengthening the spleen and replenishing qi, regulating menstruation and activating blood.Control irregular menstruation, deficiency of Yin leukorrhea."

Radix glycyrrhizae：It is sweet；It is mild-natured.The thoughts of returning home；Lung；Spleen；Stomach.Invigorate the spleen and benefit qi；It is clearing heat and detoxicating；Expelling phlegm and arresting coughing；Relieving spasm to stop pain；Reconcile all Medicine.Cure mainly weakness of the spleen and the stomach；Lassitude hypodynamia；Palpitation；Coughing with a lot of sputum；Gastral cavity abdomen four limbs contraction；Carbuncle sore tumefacting virus；Alleviate medicine Toxicity.《Compendium of Materia Medica》Carry：" radix glycyrrhizae is monarch in all medicines.Control 72 kinds of mammary calculus poison, the draft poison by every means of solution 1,002, reconcile from Medicine is active." modern medicine study confirms that radix glycyrrhizae has a stronger detoxication, also antiulcer, anti-inflammatory, antispastic antibechic, drop blood Pressure, reducing blood lipid, antitumaous effect, it is widely used in the diseases such as treatment sphagitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis Disease, additionally acted on anti-gastric-ulcer, gastritis.

Radix Codonopsis：It is sweet；It is mild-natured.Returns spleen；Lung channel.Strengthening the spleen and tonifying the lung；Nourishing generate fluid.Cure mainly weakness of the spleen and the stomach；Anorexia and loose stool；Four limbs It is weak；The deficiency syndrome of the lung is breathed with cough；Shortness of breath spontaneous perspiration；The all cards of qi-blood deficiency.《Moral is with book on Chinese herbal medicine》Carry：" clearing lung-heat gold, tonifying primordial Qi, opens sound, helps muscle Power." modern medicine study confirmation, Radix Codonopsis energy Gastrointestinal motility adjustment, antiulcer, enhancing immunologic function, to excited and two kinds of suppression Nerve process all has an impact, and can raise red blood cell, hemoglobin, granulophilocyte, also anti-aging and anti-oxidant, anti-spoke The effect penetrate, being depressured.

Variegated leaf is blue：It is sweet；It is pungent；It is mild-natured.Moisten the lung and relieve the cough；Tonify Qi of the kidney；The promoting flow of qi and blood circulation；Subdhing swelling and detoxicating.Cure mainly pulmonary tuberculosis cough； Tracheitis；It is dizzy weak；Neurasthenia；Impotence；Traumatic injury；Arthralgia；Abscess of throat；Acute mastitis；Boil；Scrofula；Poisonous snake Bite.《Zhejiang conventional herbal medicine among the people》：" clearing heat and detoxicating, anti-inflammatory detumescence.Control venomous snake bite, carbuncle swells boil, tuberculosis cough, tracheae It is scorching."

Fiveleaf akebia fruit：Slight bitter is hidden, it is mild-natured.Return liver, stomach, bladder warp.Soothing liver and harmonizing stomach, promoting blood circulation and stopping pain, softening and resolving hard mass, diuresis.Cure mainly Stagnation of liver-QI and stomach-QI, gastral cavity abdomen, the side of body help distending pain, and diet does not disappear, and diarrhea is just let out, hernia pain, pain in the back, closed dysmenorrhea, goiter and tumor scrofula, pernicious Tumour.《Shaanxi Chinese herbal medicine》：Shugan Yishen, strengthening the spleen and stomach.Indigestion is controlled, is suffered from abdominal pain, rush down dysentery, hernia, uterus tenesmus.

Wilsonii：Acrid flavour；Slight bitter；It is warm-natured.Returns spleen；Kidney；The heart channel of Hang-Shaoyin.Replenishing kidney, strengthening waist；Benefiting qi for tranquillization；It is promoting blood circulation and removing obstruction in channels.Main kidney deficiency It is weak；Soreness and weakness of waist and knees；Children's retardation of walking；It is insufficiency of the spleen weak；Deficiency of vital energy edema；Poor appetite；Insomnia and dreamful sleep；It is forgetful；Obstruction of qi in the chest pain；Chill Arthritis with fixed pain caused by dampness；Treating swelling and pain by traumatic injury.Modern medicine study prove its extract can effective anti-inflammation, have fabulous anti-aging effects.

The root of herbaceous peony：Bitter；It is mild-natured.Enter liver；The spleen channel.Nourishing blood and liver, relieved pain in delaying；Hold back cloudy receipts sweat.Cure mainly chest and abdomen pain over the hypochondriac region, Diarrhea dysentery abdominal pain, spontaneous sweating, fever due to yin deficiency.《Do not record》Carry：" clear and coherent blood vessels, in delaying, dispelling malignant blood, expelling extravasated blood, remove aqueous vapor, sharp wing Guang, intestine and small intestine, subduing inflammation, row fever and chills when controlling are middle to dislike stomachache, pain in the back." modern medicine study confirm, the root of herbaceous peony can adjust it is immune, increase The phagocytic function of strong macrophage and leucocyte, adjust the immunologic function of T lymphocytes and body fluid, have liver protection, spasmolysis, analgesia, Calm, anti-cool, cooling effect, additionally there are inhibitory action, enhancing resist oxygen lack, anti-oxidant and antifatigue effect to smooth muscle.

Common Achyranthes Herb：Bitter；Acid；Cold nature.Return liver；Lung；Bladder warp.It is promoting blood circulation and removing blood stasis；Inducing diuresis for treating strangurtia；Relieving superficies by cooling.Cure mainly Amenorrhea；Dysmenorrhoea；Irregular menstruation；Traumatic injury；Rheumatic arthritis；Gonorrhoea；Oedema；Under humid tropics, fever caused by exogenous pathogens；Malaria；Pharyngalgia； Furunculosis carbuncle swells.《Conventional Chinese herbal medicine handbook》：Heat-clearing, Li Shui, strengthening tendons, dissipate blood.Cured cold heating, and heat is not moved back long, rheumatism joint Inflammation, pain in waist and lower extremities, laryngalgia, hypertension, nephritic dropsy.

Intermediate peashrub root：Taste micro-pungent；It is warm-natured.The thoughts of returning home；Liver Channel.Supplementing qi and nourishing yin.Cure mainly：Dizziness, palpitaition, shortness of breath and fatigue, hypertension Disease.

Weak ixeris herb：Bitter；It is cold in nature.Return stomach；Intestines；Kidney channel.It is clearing heat and detoxicating；Inducing diuresis to remove edema.Cure mainly lung abscess；Pharyngalgia；Hot eyes； Mastitis；Ulcer sores；Oedema；Difficult urination.

Centella：Bitter；It is pungent；It is cold in nature.Return lung；Spleen；Kidney；Bladder warp.Clearing heat and promoting diuresis；Promoting blood circulation and hemostasis；Removing toxicity for detumescence.Cure mainly Heating；Cough and asthma；Abscess of throat；Stomach pain；Dysentery；Jaundice with damp-heat pathogen；Oedema；Stranguria；Hematuria；Bleeding from five sense organs or subcutaneous tissue；Dysmenorrhoea；Uterine bleeding；Erysipelas；Scrofula Scrofula；Close pyogenic infections from tumour or sore；Herpes zoster；Treating swelling and pain by traumatic injury；Traumatism and bleeding；Snake bite and insect sting.《Book on Chinese herbal medicine asks former》：Except heat toxin, gonorrhoea is controlled, soaks infantile malnutrition due to digestive disturbances or intestinalparasites Sore, manage small intestine-QI.

Smallflower beggarticks herb：Mildly bitter flavor；Micro-pungent；It is cool in nature.Clearing heat and promoting diuresis；Removing toxicity for detumescence；Promoting blood circulation and hemostasis.Cure mainly dysentery；Diarrhea edema； Cough；Asthma；Tonsillitis；Hemoptysis；Hematuria；Carbuncle furuncle poison；Herpes zoster；Treating swelling and pain by traumatic injury；Traumatism and bleeding.《Quanzhou book on Chinese herbal medicine》： It is clearing heat and detoxicating, stasis eliminatings promoting blood circulation, regulating fluid apssage.Control ulcer furuncle, hot urination.

Road blocking tiger：Bitter；It is cold in nature.Return lung；Bladder warp.It is clearing heat and detoxicating；Inducing diuresis to remove edema；Stimulate the menstrual flow lower breast.Cure mainly abscess of throat； Oedema tinea pedis；Damp-heat gonorrhoea；Amenorrhoea；Puerpera's breast sweat not under.

The fruit of Chinese magnoliavine：Acrid flavour；It is bitter；It is warm-natured.Restrain astringent or styptic treatment for spontaneous sweating；Nourishing generate fluid；Kidney calming；Expelling wind and removing dampness；Vital energy regualting and blood circulation-promoting.Cure mainly Treating rheumatic ostealgia；Traumatic injury；Stomachache；Irregular menstruation；Ephritis.《This warp》Carry：" main QI invigorating, cough with dyspnea, the thin degree of internal lesion caused by overexertion, mend not Foot, Qiang Yin." modern medicine study confirms that the fruit of Chinese magnoliavine contains abundant organic acid, vitamin, flavonoids, phytosterol and had strong Imitate the lignan of reactivation, it is also to have essence, gas, one of a small number of medicinal materials of refreshing three big helps concurrently, can the strong liver of QI invigorating, promote carefully Born of the same parents exclude the efficiency of waste, supply more oxygen, nutrition and use energy, improve memory and property endurance.

The present invention compared with prior art, has the advantages that：

The present invention is mutually suitable mutually auxiliary from the property of medicine of medicinal material, is suited the remedy to the case for the cause of disease, has strengthening spleen, tonifying kidney, soft liver is soothing the liver, QI invigorating is supported The effect of cloudy, clearing heat and detoxicating, promoting blood circulation and removing blood stasis, anti-inflammation hemostasia, dispersing swelling and dissipating binds, resolving sputum diuresis, good absorbing effect is evident in efficacy, nothing Toxic side effect and clinical adverse are higher to malakoplakis of bladder cure rate according to clinical verification.

Embodiment

The present invention is further elaborated with reference to specific embodiment.

Embodiment 1

The raw material of effective ingredient of the present invention forms and weight is：

Cup 25~40 parts of chrysanthemum, 20~30 parts of cuneate lespedeza herb with root, 15~30 parts of Chinese yam, 15~30 parts of bunge bedstraw herb,

15~30 parts of cowpea, 10~25 parts of horse hail, 10~25 parts of the bighead atractylodes rhizome, 10~25 parts of juglandis,semen,

9~20 parts of the red sage root, 9~20 parts of dindygulen peperomia herb, 9~15 parts of unpleasant swallowwort herb, 9~15 parts of radix glycyrrhizae,

6~12 parts of Radix Codonopsis, 6~12 parts of variegated leaf orchid, 5~10 parts of fiveleaf akebia fruit, 5~10 parts of wilsonii,

5~10 parts of the root of herbaceous peony, 4~9 parts of Common Achyranthes Herb, 4~9 parts of intermediate peashrub root, 4~9 parts of weak ixeris herb,

3~7 parts of centella, 3~7 parts of smallflower beggarticks herb, 2~6 parts of road blocking tiger, 1~3 part of the fruit of Chinese magnoliavine.

The processing step of process for preparing medicine of the present invention is：

（1）By cup chrysanthemum, cuneate lespedeza herb with root, Chinese yam, bunge bedstraw herb, cowpea, horse hail, the bighead atractylodes rhizome, juglandis,semen, unpleasant swallowwort herb, Common Achyranthes Herb, caragana microphylla Root, weak ixeris herb, centella, smallflower beggarticks herb, road blocking tiger clean dry after be well mixed, be put into container, in a reservoir add 6~8 The water of amount again, heating are boiled 2~3 hours, and immersion liquid is taken after cooling；The water of 4~6 times of amounts, heating are added in the remaining dregs of a decoction Boil 1~2 hour, immersion liquid is taken after cooling；Merge gained immersion liquid twice, heating, be concentrated by evaporation as relative density 1.15~1.25 Thick paste, it is standby；

（2）Danshen Tablets are taken, add yellow rice wine to mix thoroughly, vexed profit is put in pot, fried with slow fire to saturating, and taking-up is cooled, and crushing is ground, and crosses 100 mesh Dusting cover, fine powder is obtained, it is standby；

（3）Dindygulen peperomia herb, variegated leaf orchid, fiveleaf akebia fruit, wilsonii, the fruit of Chinese magnoliavine are put into container, add the shao-hsing rice wine of 3~5 times of amounts, Cooled after boiling, continue immersion 3~5 hours, take immersion liquid；The shao-hsing rice wine of 2~4 times of amounts is added in the remaining dregs of a decoction, is boiled Cooled after boiling, continue immersion 2~4 hours, take immersion liquid；Merge gained immersion liquid twice, it is relative density 1.10 to add steaming to be concentrated by evaporation ~1.20 thick paste, it is standby；

（4）Net licorice tablet is taken, adds cooked honey and a little boiling water, it is slightly vexed after mixing thoroughly, put in frying container, slow fire is fried to depth Yellow, take out, cool when tack-free, crushing is ground, and is crossed 100 mesh dusting covers, is obtained fine powder, standby；

（5）Wheat bran is placed in the pot of heating, to pot on when playing cigarette, add Radix Codonopsis piece, stir to buff, taking-up and weed out bran Skin, cool, crushing is ground, and is crossed 100 mesh dusting covers, is obtained fine powder, standby；

（6）Take root of herbaceous peony piece, spray yellow rice wine is mixed thoroughly, and vexed profit is put in pot to saturating, is fried with slow fire slightly yellow to surface, and taking-up cools, powder It is broken to grind, 100 mesh dusting covers are crossed, obtain fine powder, it is standby；

（7）By step（1）, step（3）The thick paste of gained, with step（2）, step（4）, step（5）, step（6）Middle gained Fine powder mixes, and adds auxiliary material sucrose and dextrin to be well mixed and particle is made, dries, after whole grain, be packaged into every bag of 8g instant particles as Chinese medicine.

Usage and dosage：Orally, 3 times a day, every time 1 bag, taken after mixing it with water with boiling water within 1 hour after meal, 7 days are 1 course for the treatment of.

Embodiment 2

The raw material of effective ingredient of the present invention forms and weight is：

Cup 30~36 parts of chrysanthemum, 23~28 parts of cuneate lespedeza herb with root, 18~25 parts of Chinese yam, 18~25 parts of bunge bedstraw herb,

18~24 parts of cowpea, 15~20 parts of horse hail, 15~20 parts of the bighead atractylodes rhizome, 15~20 parts of juglandis,semen,

12~18 parts of the red sage root, 12~16 parts of dindygulen peperomia herb, 11~13 parts of unpleasant swallowwort herb, 11~13 parts of radix glycyrrhizae,

8~10 parts of Radix Codonopsis, 8~10 parts of variegated leaf orchid, 6~9 parts of fiveleaf akebia fruit, 6~8 parts of wilsonii,

6~8 parts of the root of herbaceous peony, 5~7 parts of Common Achyranthes Herb, 5~7 parts of intermediate peashrub root, 5~7 parts of weak ixeris herb,

4~6 parts of centella, 4~6 parts of smallflower beggarticks herb, 3~5 parts of road blocking tiger, 1~2 part of the fruit of Chinese magnoliavine.

The process for preparing medicine processing step and usage and dosage of the present embodiment are same as Example 1.

Embodiment 3

The raw material of effective ingredient of the present invention forms and weight is：

Cup 34 parts of chrysanthemum, 26 parts of cuneate lespedeza herb with root, 23 parts of Chinese yam, 22 parts of bunge bedstraw herb,

22 parts of cowpea, 18 parts of horse hail, 18 parts of the bighead atractylodes rhizome, 18 parts of juglandis,semen,

16 parts of the red sage root, 14 parts of dindygulen peperomia herb, 12 parts of unpleasant swallowwort herb, 12 parts of radix glycyrrhizae,

9 parts of Radix Codonopsis, variegated leaf are blue 9 parts, 8 parts of fiveleaf akebia fruit, 7 parts of wilsonii,

7 parts of the root of herbaceous peony, 6 parts of Common Achyranthes Herb, 6 parts of intermediate peashrub root, 6 parts of weak ixeris herb,

5 parts of centella, 5 parts of smallflower beggarticks herb, 4 parts of road blocking tiger, 1 part of the fruit of Chinese magnoliavine.

The process for preparing medicine processing step and usage and dosage of the present embodiment are same as Example 1.

Clinical data：

1st, case selection

47 clinical observations of malakoplakis of bladder patient that selection our hospital makes a definite diagnosis, patient are randomly divided into two groups.Treatment group 23, female Property, 44~69 years old age, average age 58.6 years old.Control group 24, women, 46~68 years old age, average age 59.2 years old.Two Group qualifications and record of service are basically identical, no significant difference, have comparativity.

2nd, treatment group patient takes medicine of the present invention, orally, 3 times a day, 1 bag every time, is taken after mixing it with water with boiling water within 1 hour after meal, and 7 It is 1 course for the treatment of, takes 3~6 courses for the treatment of；

Control group gives the treatment of quinolione class antimicrobial to the ill according to the classification for the malakoplakis of bladder being diagnosed to be.

3rd, efficacy determination：

（1）Recovery from illness：The clinical symptoms such as gross hematuria and urinary tract infection symptom all disappear, physical recovery health.

（2）Take a turn for the better：The clinical symptoms such as gross hematuria and urinary tract infection symptom substantially mitigate, and body is clearly better,.

（3）It is invalid：Symptom is same to treat preceding no significant difference.

4th, result

18 are cured in treatment group, is taken a turn for the better 3, invalid 2, cure rate 78.3%, total effective rate 91.3%.

13 are cured in control group, is taken a turn for the better 7, invalid 4, cure rate 54.2%, total effective rate 83.3%.

Result above shows, the cure rate and total effective rate for the treatment of group are apparently higher than control group.

Model case is illustrated：

1st, Cai's ××, female, 55 years old.The patient patient's Silent Neuritis, the gross hematuria, coagulates because hematuria is hospitalized for treatment with a small amount of trace of blood Block, lower abdomen occasionally have falling inflation sense of discomfort, and without obvious urinary tract infection disease, no heating and night sweat, bladder area carry without tenderness, ultrasound diagnosis Show Bladder Tumor, be diagnosed as malakoplakis of bladder, after taking 3 courses for the treatment of of Chinese medicine of the present invention, above-mentioned symptom is obvious Mitigate, hematuria phenomenon significantly reduces.To follow the doctor's advice after continuing to take 1 course for the treatment of of Chinese medicine of the present invention, above-mentioned symptom is wholly absent, Follow-up has been fully recovered for 3 months without recurrence.

2nd, Guo's ××, female, 58 years old.Patient's Silent Neuritis hematuria is hospitalized for treatment, and the patient haves a medical check-up without exception, no frequent micturition, urine The discomforts such as urgency, odynuria, ultrasound diagnosis prompting Bladder Tumor, be diagnosed as malakoplakis of bladder, through take it is of the present invention in After 5 courses for the treatment of of medicine, above-mentioned symptom is wholly absent, and follow-up has been fully recovered for 3 months without recurrence.

Malakoplakis of bladder is a kind of not clear special inflammatory reaction of reason, easily comes across immuuoeorapromised host.This hair Bright Chinese medicine is suited the remedy to the case according to the cause of disease, in side Radix Codonopsis, the bighead atractylodes rhizome, Chinese yam, variegated leaf orchid, wilsonii, the fruit of Chinese magnoliavine, juglandis,semen, night close The Chinese medicines such as door, unpleasant swallowwort herb, cowpea, intermediate peashrub root can tonify Qi of the kidney, strengthening the spleen and tonifying the lung, supplementing qi and nourishing yin, the promoting flow of qi and blood circulation；The root of herbaceous peony, eight in side Month letter can nourishing blood and liver, soothing liver and harmonizing stomach, softening and resolving hard mass；The Chinese medicine such as the red sage root, dindygulen peperomia herb, Common Achyranthes Herb can promoting blood circulation and removing blood stasis, Li Shui in side Detumescence；The Chinese medicine such as cup chrysanthemum, road blocking tiger, weak ixeris herb, bunge bedstraw herb, horse hail, centella, smallflower beggarticks herb can clearing heat and detoxicating, anti-inflammatory in side Hemostasis, dispersing swelling and dissipating binds, resolving sputum diuresis；Radix glycyrrhizae can relieving spasm to stop pain, coordinating the drug actions of a prescription in side；All medicines share can play invigorating the spleen benefit altogether in side Kidney, soft liver is soothing the liver, supplementing qi and nourishing yin, clearing heat and detoxicating, promoting blood circulation and removing blood stasis, anti-inflammation hemostasia, dispersing swelling and dissipating binds, resolving sputum diuresis the effect of, can carry High body immunity, anti-inflammation, the reparation and regeneration of promotion organization, effective symptom management development, equilibrium between yin and yang is adjusted, is reached To the purpose to return to one's perfect health, good absorbing effect is evident in efficacy, has no toxic side effect and clinical adverse, according to clinical verification to wing The soft pinta cure rate of Guang is higher.

Claims (4)

1. a kind of instant particles as Chinese medicine for treating malakoplakis of bladder, it is characterised in that the raw material composition of the effective ingredient is made And parts by weight are：

Cup 25~40 parts of chrysanthemum, 20~30 parts of cuneate lespedeza herb with root, 15~30 parts of Chinese yam, 15~30 parts of bunge bedstraw herb,

15~30 parts of cowpea, 10~25 parts of horse hail, 10~25 parts of the bighead atractylodes rhizome, 10~25 parts of juglandis,semen,

9~20 parts of the red sage root, 9~20 parts of dindygulen peperomia herb, 9~15 parts of unpleasant swallowwort herb, 9~15 parts of radix glycyrrhizae,

6~12 parts of Radix Codonopsis, 6~12 parts of variegated leaf orchid, 5~10 parts of fiveleaf akebia fruit, 5~10 parts of wilsonii,

5~10 parts of the root of herbaceous peony, 4~9 parts of Common Achyranthes Herb, 4~9 parts of intermediate peashrub root, 4~9 parts of weak ixeris herb,

3~7 parts of centella, 3~7 parts of smallflower beggarticks herb, 2~6 parts of road blocking tiger, 1~3 part of the fruit of Chinese magnoliavine.

2. a kind of instant particles as Chinese medicine for treating malakoplakis of bladder according to claim 1, it is characterised in that the medicine is made The raw material of active ingredient forms and parts by weight are：

Cup 30~36 parts of chrysanthemum, 23~28 parts of cuneate lespedeza herb with root, 18~25 parts of Chinese yam, 18~25 parts of bunge bedstraw herb,

18~24 parts of cowpea, 15~20 parts of horse hail, 15~20 parts of the bighead atractylodes rhizome, 15~20 parts of juglandis,semen,

12~18 parts of the red sage root, 12~16 parts of dindygulen peperomia herb, 11~13 parts of unpleasant swallowwort herb, 11~13 parts of radix glycyrrhizae,

8~10 parts of Radix Codonopsis, 8~10 parts of variegated leaf orchid, 6~9 parts of fiveleaf akebia fruit, 6~8 parts of wilsonii,

6~8 parts of the root of herbaceous peony, 5~7 parts of Common Achyranthes Herb, 5~7 parts of intermediate peashrub root, 5~7 parts of weak ixeris herb,

4~6 parts of centella, 4~6 parts of smallflower beggarticks herb, 3~5 parts of road blocking tiger, 1~2 part of the fruit of Chinese magnoliavine.

3. a kind of instant particles as Chinese medicine for treating malakoplakis of bladder according to claim 1, it is characterised in that the medicine is made The raw material of active ingredient forms and parts by weight are：

Cup 34 parts of chrysanthemum, 26 parts of cuneate lespedeza herb with root, 23 parts of Chinese yam, 22 parts of bunge bedstraw herb,

22 parts of cowpea, 18 parts of horse hail, 18 parts of the bighead atractylodes rhizome, 18 parts of juglandis,semen,

16 parts of the red sage root, 14 parts of dindygulen peperomia herb, 12 parts of unpleasant swallowwort herb, 12 parts of radix glycyrrhizae,

9 parts of Radix Codonopsis, variegated leaf are blue 9 parts, 8 parts of fiveleaf akebia fruit, 7 parts of wilsonii,

7 parts of the root of herbaceous peony, 6 parts of Common Achyranthes Herb, 6 parts of intermediate peashrub root, 6 parts of weak ixeris herb,

5 parts of centella, 5 parts of smallflower beggarticks herb, 4 parts of road blocking tiger, 1 part of the fruit of Chinese magnoliavine.

A kind of 4. preparation method for being used to treat the instant particles as Chinese medicine of malakoplakis of bladder and preparation method thereof, it is characterised in that including Following processing step：

（1）By cup chrysanthemum, cuneate lespedeza herb with root, Chinese yam, bunge bedstraw herb, cowpea, horse hail, the bighead atractylodes rhizome, juglandis,semen, unpleasant swallowwort herb, Common Achyranthes Herb, caragana microphylla Root, weak ixeris herb, centella, smallflower beggarticks herb, road blocking tiger clean dry after be well mixed, be put into container, in a reservoir add 6~8 The water of amount again, heating are boiled 2~3 hours, and immersion liquid is taken after cooling；The water of 4~6 times of amounts, heating are added in the remaining dregs of a decoction Boil 1~2 hour, immersion liquid is taken after cooling；Merge gained immersion liquid twice, heating, be concentrated by evaporation as relative density 1.15~1.25 Thick paste, it is standby；

（2）Danshen Tablets are taken, add yellow rice wine to mix thoroughly, vexed profit is put in pot, fried with slow fire to saturating, and taking-up is cooled, and crushing is ground, and crosses 100 mesh Dusting cover, fine powder is obtained, it is standby；

（3）Dindygulen peperomia herb, variegated leaf orchid, fiveleaf akebia fruit, wilsonii, the fruit of Chinese magnoliavine are put into container, add the shao-hsing rice wine of 3~5 times of amounts, Cooled after boiling, continue immersion 3~5 hours, take immersion liquid；The shao-hsing rice wine of 2~4 times of amounts is added in the remaining dregs of a decoction, is boiled Cooled after boiling, continue immersion 2~4 hours, take immersion liquid；Merge gained immersion liquid twice, it is relative density 1.10 to add steaming to be concentrated by evaporation ~1.20 thick paste, it is standby；

（4）Net licorice tablet is taken, adds cooked honey and a little boiling water, it is slightly vexed after mixing thoroughly, put in frying container, slow fire is fried to depth Yellow, take out, cool when tack-free, crushing is ground, and is crossed 100 mesh dusting covers, is obtained fine powder, standby；

（5）Wheat bran is placed in the pot of heating, to pot on when playing cigarette, add Radix Codonopsis piece, stir to buff, taking-up and weed out bran Skin, cool, crushing is ground, and is crossed 100 mesh dusting covers, is obtained fine powder, standby；

（6）Take root of herbaceous peony piece, spray yellow rice wine is mixed thoroughly, and vexed profit is put in pot to saturating, is fried with slow fire slightly yellow to surface, and taking-up cools, powder It is broken to grind, 100 mesh dusting covers are crossed, obtain fine powder, it is standby；

（7）By step（1）, step（3）The thick paste of gained, with step（2）, step（4）, step（5）, step（6）Middle gained Fine powder mixes, and adds auxiliary material sucrose and dextrin to be well mixed and particle is made, dries, after whole grain, be packaged into every bag of 8g instant particles as Chinese medicine.