CN107693746A

CN107693746A - Treat pharmaceutical composition of the proliferation of mammary gland and preparation method thereof

Info

Publication number: CN107693746A
Application number: CN201710970236.1A
Authority: CN
Inventors: 曹国荣; 曹达
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-10-18
Filing date: 2017-10-18
Publication date: 2018-02-16

Abstract

A kind of pharmaceutical composition for treating the proliferation of mammary gland of the present invention and preparation method thereof, its pharmaceutical composition main component are the Radix Astragali, turpentine, cedar sawdust（China fir）, Ligusticum wallichii, Radix Angelicae Sinensis, cultivated land, return tail, the Radix Astragali, safflower, peach kernel, the red sage root, the radix paeoniae rubrathe, interior gold, hawthorn, Rhizoma Sparganii, curcuma zedoary, pseudo-ginseng, radix scrophulariae, earthworm, the root of Chinese clematis take its decocting extraction prepare medicament, the present invention focuses on tonifying Qi and lifting yang with promoting circulation of blood, tonifying Qi is with logical numbness, strengthen life power, strengthen the viable organism energy, promoting blood circulation and removing blood stasis, adjustment life organic whole balance, nourish congenital kidney water, the health care taste day after tomorrow.On the one hand function of human body work is coordinated, on the one hand through focus is assaulted fortified position；On the one hand take away the firewood under the cauldron, optimize rehabilitation environment, also nourishing Yin and falling fire, clearing heat and detoxicating, cool blood promote the production of body fluid, and softening and resolving hard mass disappears carbuncle, righting eliminating evil again, and eliminating evil is not hindered just, curative effect is rapidly, short treating period, non-evident effect, it is the choice drug for quite preferably treating the proliferation of mammary gland.

Description

Treat pharmaceutical composition of the proliferation of mammary gland and preparation method thereof

Technical field

The present invention relates to a kind of pharmaceutical composition for treating the proliferation of mammary gland and preparation method thereof.

Background technology

The proliferation of mammary gland is the most common breast disease of women, is mammoplasia neither tumour, is also not belonging to inflammation And retrogression, it is closely related with endocrine dysfunction.This disease is apt to occur in middle-aged women, and teenager and postmenopausal women also have Occur, its incidence of disease accounts for the first place of mammary gland disease, and the sick incidence of disease was in the trend risen year by year in the last few years, and the age is also increasingly Become younger.There are about 70%~80% women according to investigations has the different degrees of proliferation of mammary gland, is more common in the women of 25~45 years old.Breast Gland hyperplasia disease often shows as breast pain and mammary gland touches tubercle, and it endangers and does not lie in disease in itself, but psychological pressure, load The heart, which be can do by myself, will not suffer from breast cancer or can become cancer later.Cyclomastopathy has polytype, such as pure lobular hyperplasia（Account for The major part of cyclomastopathy）, only it is noted that adjusting mentality, alleviate pressure, it is possible to gradually alleviate.If hyperplasia of mammary glands companion Epithelial hyperplasia, and severe abnormity is presented, then it is precancerous lesion（Account for few part）, need active treatment to inspect periodically, prevent Suffer from possible trouble.

Mammary gland, with the change of menstrual cycle, has hyperplasia in the presence of endocrine hormone, particularly Estrogen and progestin With the change of restoration of old ways.Cause endocrine hormone metabolic imbalance for some reason, estrogen level increases, and mammary gland group can occurs Overgrown and subinvolution are knitted, after after a while, the breast tissue of hyperplasia can not disappear completely, just form mammary gland and increase Raw disease.

Have a different characteristics in age groups, unmarried female, it is married do not educate, the women of not yet lactation, its cardinal symptom is Distending pain of the breast, bilateral can be involved simultaneously, but be laid particular stress on more with side.Distending pain of the breast is obvious before menstruation, and menstruation is shown in mitigation simultaneously later Tapering off, pain occurs once again before next menstruation comes, and whole breast has diffusivity tubercle sense, and with tenderness.After 35 years old Women's cardinal symptom is breast lump, and breast pain and tenderness are lighter and unrelated with the menstrual cycle.Size can be touched by touching breast with hand Do not wait, oblate or irregular shape, quality flexible tubercle, obscure boundary Chu, with skin and deep tissue without adhesion, can be pushed away It is dynamic.The single or multiple Cystic lesions being dispersed in often are shown as after 45 years old, clear border, more with blunt pain, distending pain or burn feeling. Postmenopausal women's mammary gland atrophy, cystic lesion are more prominent.The presence or absence of the order of severity of breast pain and tubercle and scope Non-correlation, pain can radiate to oxter, shoulder back.It may also occur that menstruation irregularis, has a bad temper, like to worry anger, like The symptoms such as sweat.Because the cause of disease comes from body endocrine dysfunction, therefore simultaneously it may also occur that menstruation in addition to the symptom in terms of breast It is irregular, have a bad temper, like to worry the symptoms such as love is angry, love is perspired.

2nd, 1. psychotherapy

The generation of cyclomastopathy often with it is tired, life is irregular, nervous, pressure is overweight relevant.Treat the proliferation of mammary gland Disease seeks to live and work pressure of releiving first, eliminates worry, and happy, phychology is gentle, and symptom can is alleviated.

2nd, 2. traditional Chinese medical herbal treatment

The traditional Chinese medical science thinks that cyclomastopathy starts from liver depression, and then blood stasis phlegm congeals into block, controls suitable dispersing stagnated hepatoqi, promoting blood circulation and removing blood stasis, softening hard masses dissipate Knot, radix bupleuri, the root of herbaceous peony, rhizoma cyperi, tangerine leaf, the red sage root, earthworm are the common medicine in tcm prescription.Some patients can also take Chinese patent drug, Such as：Dissipating bind is clever, newborn block disappears, breast is peaceful, RUKANG PIAN, Xiaoyao San or Danzhi Xiaoyao San（Jiawei Xiaoyao San）Deng.Mammary gland is pernicious except External treatment with Chinese medicine therapy can be also tried out on the premise of tumour, such as：Chinese medicine brassiere, acupuncture, massage etc..

2nd, 3. western medicine

Hormone medicine, Operand and TAM can be used, first choice because there is certain side effect, can not be done with pain of alleviation. Vitamin A, B6, E also have modulability functions of hormones, can be as the adjuvant drug of cyclomastopathy.

2nd, 4. operative treatment

For cyclomastopathy caused by endocrine metabolism is unbalance, itself does not have Operation indication, clinically runs into individually and breast cancer The Breast Nodules differentiated are not easy, surgery excision can be also used, be clarified a diagnosis through pathological examination.

The power of Radix Astragali help vigour not as good as ginseng, but be longer than tonifying Qi and lifting yang, benefit defends solid table, torr sore myogenic, profit water detumescence, especially It is suitable for sinking of QI due to deficiency of the spleen and exterior deficiency spontaneous perspiration etc. to be demonstrate,proved.The sweet temperature of the Radix Astragali, enters the spleen channel, is the key medicine of invigoration spleen qi.It is used for treating Spleen-Qi Deficiency The symptoms such as weak, fatigue and asthenia anorexia and loose stool.Because it is longer than yang invigorating, it is commonly used for treating caused by the insufficiency of the spleen caused sinking of qi of middle-jiao The diseases such as prolapse of the anus, splanchnoptosia.In addition, the Radix Astragali enters lung channel, while and can replenishing and restoring lung qi, available for caused by treatment insufficiency of lung-QI Cough the symptoms such as powerless, dyspnea with shortness of breath, clear, the low lazyness of sound of expectoration.The gas of Radix Astragali energy tonifying lung spleen, benefit defend solid table with hidroschesis, often Medicine with the convergence hidroschesis such as oyster, radix ephedrae is with using, to treat the exterior deficiency spontaneous perspiration caused by spleen-lung Qi deficiency, defensive Qi instability.Spleen Main transmitting and distributing the fluids, Spleen-Qi Deficiency, then transporting is ineffective, and the Radix Astragali can invigorate the spleen and benefit qi and effect a permanent cure, and and can inducing diuresis to remove edema is taken stopgap measures, and is treatment qi and blood One of important drugs of oedema.The Radix Astragali has the effect of blood-nourishing in itself, and contributes to green blood again by the effect of tonifying Qi, therefore The Radix Astragali is also commonly used for treating blood deficiency chlorosis and syndrome of deficiency of both qi and blood.The tonifying Qi of Radix Astragali function is with promoting circulation of blood, and tonifying Qi is with logical numbness.For numbness Disease, apoplexy sequelae, lose and support because of blood stagnancy due to deficiency of QI, skin, tendon and vessel, symptoms include the crowd of numbness or hemiplegia, commonly use the Radix Astragali Treated.The effect of Radix Astragali is with its benefiting qi and nourishing blood, healthy tendency can be made vigorous, after sore diabrosis, do not closed up long, can be admitted a child into a nursery school Malicious apocenosis, the effect of myogenic sore.Active ingredient astragalus polyose has shared the work(of Synergy and attenuation with antineoplastic in the Radix Astragali, that is, increases Strong anticarcinogenic effect, mitigate side effect.The Radix Astragali reduces to total serum protein caused by liver damage and albumin rise effect, and Hepatic glycogen reduction can be prevented, promote liver protein renewal.Chronic hepatitis B patient can be helped to recover immunologic function, improve clear virus Or suppress the ability of virus diffusion.The Radix Astragali has cardiotonic, can increase heart contraction amplitude, output quantity increase, centering Poison or Fatigue failure and action of the heart become apparent.In addition, for autoimmune response caused by vital myocarditis, the Radix Astragali Vital myocarditis can also be suppressed by strengthening immunologic function, and strengthen cardiac muscle cell and produce interferon and Stimulation effect interference Element effect.The Radix Astragali has certain dual regulation to blood pressure, and its boosting can be such that blood pressure somewhat rises and keep stable； Its Hypotensive Mechanism mainly directly acts on peripheral vascular, can reduce peripheral resistance by expanding peripheral vascular to reach decompression Purpose.The Radix Astragali can reduce glucose and adrenaline triggers the blood sugar level of blood glucose rise, and insoral and insulin are drawn The hypoglycemia served has rise.The Radix Astragali can resist the effect of immunodepressant, to humoral immunity, cellular immunity, reticular endothelium System, ectosome system play the role of to strengthen its function, have induction role to some immune cell factors, and induce interference The effect of element, enhancing NK, has preferable adjustment effect to panimmunity factor.

Turpentine, nature and flavor：Hardship, it is warm-natured.Channel tropism：Liver Channel, kidney channel.

Function：Dispel pathogenic wind and remove dampness, channels sootheing and network vessel quickening, promoting blood circulation and stopping pain.

Cure mainly：Wind-cold-dampness arthralgia, severe and wadering arthralgia pain, pin numbness impotence are soft, injuries from falls as well.

Usage and dosage：It is for oral administration：Decoct soup, 10-15g, or infusing drugs in wine, vinegar etc..External application：In right amount, infusing drugs in wine is embrocated, or is fried and ground tune Apply.

The careful clothes of the dry person of deficiency of Yin blood.

①《This is through meeting original》：" the dry people of blood avoids clothes.” ②《The new compilation of materia medica》：" deficiency of blood people avoids especially.”

Turpentine has certain analgesia, antiinflammatory action；The acidic polysaccharose of extraction shows antitumor action；The polysaccharose substance of extraction, Hot water extract, acidic extraction thing all have immunocompetence.

《Collected statements on the herbal foundation》：Turpentine, temperature is dry, such as sufficient knee muscles and bones, has wind to have wet, acid of having a pain, the weak powerless person of impotence, uses this It is vertical to fully recover from an illness.If deficiency of Yin marrow is weary, blood is dry fiery person, preferably considers and uses it.《Mingyi Bielu》：The long wind of main hundred section, wind is empty, pin numbness pain. 《Japan hanako materia medica》：Control pin chondromera wind.《A supplement to augmented materia medica》：Stir-bake to brown controls disease between bone, can be in dry blood it is wet.《The southern regions of the Yunnan Province sheet Grass》：Pass through network, control convulsive seizure due to phlegm-fire, arthralgia and myalgia, arthritis with fixed pain caused by dampness impotence is soft, strengthening the bones and muscles.《Grass is logical profound》：Search wind relaxing muscles and tendons.《Classify herbal》： Control the arthroncus of knee, ventilation and blood.Guangzhou army《Conventional Chinese herbal medicine handbook》：Control treating rheumatic ostealgia, bruise stasis caused pain.

Cedar sawdust（China fir）Heartwood and branch and wood sawdust for taxodiaceae plant.Nature,taste and action：Pungent, tepor, lower gas drop is inverse, Dissipate-swelling relieves pain, clearing damp detumescence.Usage and dosage：It is for oral administration：Decoct soup, 1-2 liang.China fir（Bits）Can works.It is Wen Han first The neutralization of the property of medicine, also it is exactly China fir（Bits）Subinverse gas, dissipate wet poison, have eliminating dampness exploitation rise alter function.《Book on Chinese herbal medicine warp Dredge》：" its fragrance solution is taken to paint the dirty evil of gas, the punching that pungent-warm can dissipate wet poison is inverse.”《Solar corona》：" control gas in cholera, nothing but it is false its Lower gas dissipates heresy, the work(ear of pungent-warm exploitation.”《Collected statements on the herbal foundation》：" acrid flavour temperature, through exploitation rise the property altered." " this medicine fragrant, Can subinverse gas, dissipate that poison is evil, there is the work(gone out in reaching, it is strongly fragrant to develop fire greatly, dredges the order of Shen liver, solely arrogates to oneself its elder.”

These autonomic drugs have the advantages of exploit natural resources abundant, convenient sources, cost are relatively low, easy to spread.

The present invention focuses on tonifying Qi and lifting yang and strengthens life power, the reinforcing viable organism energy is living with promoting circulation of blood, tonifying Qi to lead to numbness Blood stagnation resolvation, adjustment life organic whole balance, nourishes congenital kidney water, the health care taste day after tomorrow.On the one hand function of human body work is coordinated, On the one hand through focus is assaulted fortified position；On the one hand take away the firewood under the cauldron, optimize rehabilitation environment.

The content of the invention

It is an object of the invention to provide a kind of pharmaceutical composition for treating the proliferation of mammary gland and preparation method thereof, overcomes at present Treatment proliferation of mammary gland medicine only focus on it is promoting blood circulation and removing blood stasis and have ignored tonifying Qi and lifting yang with promoting circulation of blood, tonifying Qi with logical numbness, strengthen life power, Strengthen the viable organism energy, promoting blood circulation and removing blood stasis, softening blood vessel, expansion blood vessel and the deficiency for clearing up toxin in blood vessel.

The present invention is achieved through the following technical solutions, a kind of pharmaceutical composition for treating the proliferation of mammary gland and its preparation The therapy of method is mainly the treatment method by oral medicament composition.

Described pharmaceutical composition parts by weight of raw materials component is 5-400 parts of the Radix Astragali, 5-100 parts of turpentine, cedar sawdust（China fir） 5-100 parts, 5-100 parts of Ligusticum wallichii, 5-100 parts of Radix Angelicae Sinensis, 5-100 parts of cultivated land, return 5-100 parts of tail, 5-100 parts of safflower, peach 5-100 parts of benevolence, 5-100 parts of the red sage root, 5-100 parts of the radix paeoniae rubrathe, interior golden 5-100 parts, 5-100 parts of hawthorn, 5-100 parts of Rhizoma Sparganii, 5-100 parts of curcuma zedoary, 5-100 parts of pseudo-ginseng, 5-100 parts of radix scrophulariae, 5-100 parts of earthworm, 5-100 parts of the root of Chinese clematis.

It is optimized for 20-300 parts of the Radix Astragali, 10-50 parts of turpentine, cedar sawdust（China fir）10-50 parts, 10-50 parts of Ligusticum wallichii, when Return 10-50 parts, 10-50 parts of cultivated land, return 10-50 parts of tail, 10-50 parts of safflower, 10-50 parts of peach kernel, 10-50 parts of the red sage root, 10-50 parts of the radix paeoniae rubrathe, interior golden 10-50 parts, 10-50 parts of hawthorn, 10-50 parts of Rhizoma Sparganii, 10-50 parts of curcuma zedoary, pseudo-ginseng 10-50 Part, 10-100 parts of radix scrophulariae, 10-50 parts of earthworm, 10-50 parts of the root of Chinese clematis.

Preferably 150 parts of the Radix Astragali, 10 parts of turpentine, cedar sawdust（China fir）10 parts, 50 parts of Ligusticum wallichii, 20 parts of Radix Angelicae Sinensis, 20 parts of cultivated land, Return 50 parts of tail, 10 parts of safflower, 20 parts of peach kernel, 20 parts of the red sage root, 20 parts of the radix paeoniae rubrathe, interior golden 20 parts, 20 parts of hawthorn, 20 parts of Rhizoma Sparganii, curcuma zedoary 20 parts, 20 parts of pseudo-ginseng, 20 parts of radix scrophulariae, 20 parts of earthworm, 50 parts of the root of Chinese clematis.

A kind of pharmaceutical composition for treating the proliferation of mammary gland of the present invention and preparation method thereof, oral medicament composition by the Radix Astragali, Turpentine, cedar sawdust（China fir）, Ligusticum wallichii, Radix Angelicae Sinensis, cultivated land, return tail, safflower, peach kernel, the red sage root, the radix paeoniae rubrathe, interior gold, hawthorn, Rhizoma Sparganii, cowherb Art, pseudo-ginseng, radix scrophulariae, earthworm, sect. Clematis into.

The preparation method of described pharmaceutical composition comprises the following steps：Take the component first to use cold water soak 20 minutes, use Water is that water did not had medicine, and then decocting mixes twice, and decocting time first time is 45 minutes after boiling, pours out first time decocting medicine After liquid, add water and do not cross medicine.Second of decocting time is 30 minutes after boiling, is the extraction decoction mixing concentration of decocting twice 400 milliliters, or prepared by medicament common method.

After the preparation method, in addition to medical composition extractive concentration or medicinal extract, the side of oral medicine is routinely prepared The oral medicine that method is prepared, wherein water decoction directly can take or be made oral liquid, can also add pharmaceutically available auxiliary Material.

The medicament refers in any pharmacy described oral administered dosage form, refer in particular to granule, capsule, Tablet（Containing effervescent tablet）And oral liquid, most preferably decoction.

A kind of specific implementation operating process of pharmaceutical composition for treating the proliferation of mammary gland of the present invention and preparation method thereof：It is for oral administration Pharmaceutical composition prescription water decoction or other oral administered dosage forms：Granule, capsule, tablet（Containing effervescent tablet）And oral liquid.

The pharmacology of pharmaceutical composition prescription of the present invention is：The component Radix Astragali, tonifying Qi is with promoting circulation of blood, and rising Yang is to lead to numbness, with it For monarch drug in a prescription；Ligusticum wallichii, Radix Angelicae Sinensis, cultivated land, return tail, safflower, peach kernel, the red sage root, the radix paeoniae rubrathe, interior gold, hawthorn, Rhizoma Sparganii, curcuma zedoary, pseudo-ginseng blood-circulation-invigovating Become silted up, qi-blood tonifying, righting eliminating evil again, using it as ministerial drug；Radix scrophulariae, nourishing Yin and falling fire, clearing heat and detoxicating, cool blood are promoted the production of body fluid, and softening and resolving hard mass disappears Carbuncle, righting eliminating evil again, and eliminating evil is not hindered just, Poria cocos, Divine Comedy good efficacy to suffering from a deficiency of the kidney, using it as adjutant；Turpentine, cedar sawdust（China fir）, dispel Wind-dryness is wet, channels sootheing and network vessel quickening, promoting blood circulation and stopping pain, fragrant, energy subinverse gas, dissipates poison heresy, has the work(gone out in reaching, can develop fire greatly It is strongly fragrant, the order of Shen liver is dredged, earthworm, the root of Chinese clematis are clearing and activating the channels and collaterals with using it to make medicine.

The present invention has the following effects and advantage：

1st, botanical medicine compositions provided by the invention, the proliferation of mammary gland, tonifying Qi and lifting yang, righting eliminating evil again can be not only eliminated, and dispelled Heresy is not hindered just, moreover it is possible to is improved immunity, is dredged the blood vessel of silting.

2nd, curative effect spy is good, no obvious toxic-side effects.

4th, case report

Pharmaceutical composition decoction treats 35, and PRELIMINARY RESULTS brief summary is as follows：

1st, general information

1.1 case selection

In 35, less than 20 years old 3,20-30 years old 6,30-40 years old 8,40-50 years old 11,50-60 years old 7.

1.3 proliferation of mammary gland situations

1. oldest proliferation of mammary gland patient is XX, female, 54 years old, the villager of Hunan Yongxing County, breast lump, can lay one's hand on and side The not very clear sheet lump in boundary, or it is rough, and quality is harder, the circular tubercle to differ in size.Pathology be parenchyma and The equal hyperplasia of matter, ductal ectasia can be with knurl sample tubercle.After taking ten doses of Chinese medicines orally, distending pain of the breast disappears, and energy takes a turn for the better.It is for oral administration After 30 doses of Chinese medicines, breast lump disappears.

2. most typical proliferation of mammary gland patient is Tang's ××, female, 52 years old, Hunan Yongxing County town dweller, distending pain of the breast, together When involve bilateral, but laid particular stress on side.Distending pain of the breast is obvious before menstruation, and menstruation is shown in later to be mitigated and taper off, the next moon Occurring once again through pain before coming, whole breast has diffusivity tubercle sense, and with tenderness.After taking ten doses of Chinese medicines orally, distending pain of the breast Disappear, energy takes a turn for the better, and after taking 30 doses of Chinese medicines orally, breast lump disappears.

2nd, treatment method：

Medication compositions water decoction first, one day one two clothes or three clothes, postprandial for oral administration, auf nuechternen Magen einnehmen injuring spleen-stomach.

3rd, treatment results：

3.1st, medication compositions water decoction, after taking ten doses of Chinese medicines orally, distending pain of the breast disappears, and energy takes a turn for the better；It is for oral administration 30 doses After Chinese medicine, breast lump disappears, in addition to toxin expelling of suffering from diarrhoea, non-evident effect after all patient's medications, and effective percentage 100%.

4th, discuss：

Cyclomastopathy starts from liver depression, and then blood stasis phlegm congeals into block, controls suitable dispersing stagnated hepatoqi, promoting blood circulation and removing blood stasis, softening and resolving hard mass.The present invention A kind of pharmaceutical composition for treating the proliferation of mammary gland and preparation method thereof.Mainly focus on tonifying Qi and lifting yang, channels sootheing and network vessel quickening, dissipate poison heresy, Have reach in go out work(, can develop greatly fire it is strongly fragrant, dredge Shen liver order, activated blood circulation and dispersed blood clots eliminating evil, and nourishing Yin and clearing heat removing toxic substances, cool blood are promoted the production of body fluid, softening hard masses Dissipating bind disappears carbuncle, toxin in softening blood vessel, expansion blood vessel and cleaning blood vessel.

5th, conclusion

A kind of pharmaceutical composition for treating the proliferation of mammary gland of the present invention and preparation method thereof, effective percentage 100%, and curative effect is rapidly, the course for the treatment of It is short, non-evident effect, it is the choice drug for quite preferably treating the proliferation of mammary gland.

6th, points for attention

Must suffer from diarrhoea toxin expelling during patient's medication, not wound body of suffering from diarrhoea.

7th, avoid

The present invention disables to cachectic patients caused by advanced age weak patients and serious disease and organ failure, digestive function exhaustion person, The cold of insufficiency type suitable to taste, big loose stool and let out before medication, stomach Qi disables exhausted patient, avoids clothes during traditional Chinese medicine for oral administration and decocts, fries, stir-fries and eats Thing, avoid eating sour food.

A kind of pharmaceutical composition for treating the proliferation of mammary gland of the present invention can not be with other Chinese and Western medicines while using.

Model case 1

Tang's ××, female, 52 years old, Hunan Yongxing County town dweller, distending pain of the breast, while involve bilateral, but laid particular stress on side.Menstruation Preceding distending pain of the breast is obvious, and menstruation is shown in later to be mitigated and taper off, and pain occurs once again before next menstruation comes, and whole breast has Diffusivity tubercle sense, and with tenderness.After taking ten doses of Chinese medicines orally, distending pain of the breast disappears, and energy takes a turn for the better, and takes 30 doses of Chinese medicines orally Afterwards, breast lump disappears.

Model case 2

What xx, female, 51 years old, the villager of Hunan Hengnan County, mammary gland had lump, and breast aches but tenderness is lighter, unrelated with the menstrual cycle.With Hand touch breast can touch differ in size, oblate or irregular shape, quality flexible tubercle, obscure boundary Chu, with skin and Deep tissue can promote without adhesion.After taking ten doses of Chinese medicines orally, distending pain of the breast disappears, and energy takes a turn for the better.Take 30 doses of Chinese medicines orally Afterwards, breast lump disappears.

Model case 3

Cao's ××, female, 33 years old, the villager of Hunan Yongxing County, breast pain was dull pain or alters pain and have tenderness, and distending pain is obvious, swells Block is larger, or in the form of sheets, plate-like, involve double breasts.After taking ten doses of Chinese medicines orally, distending pain of the breast disappears, and energy takes a turn for the better.For oral administration 30 After agent Chinese medicine, breast lump disappears.

Model case 4

Lee XX, female, 44 years old, Hunan Yongxing County just Jiang Zhen resident, can be laid one's hand on through foremilk pain, during inspection and irregularly, boundary it is unclear, Rough, strong but pliable in texture lump, no tenderness.Pathology is shown in interstitial fibrosis, small lobar atrophy or disappearance, glandular tube deformation.It is interior After taking ten doses of Chinese medicines, distending pain of the breast disappears, and energy takes a turn for the better.After taking 30 doses of Chinese medicines orally, breast lump disappears.

Model case 5

XX, female, 54 years old, the villager of Hunan Yongxing County, breast lump can be laid one's hand on and the not very clear sheet lump in border, or table Face is rough, and quality is harder, the circular tubercle to differ in size.Pathology is parenchyma and the equal hyperplasia of interstitial, and ductal ectasia can be with knurl Sample tubercle.After taking ten doses of Chinese medicines orally, distending pain of the breast disappears, and energy takes a turn for the better.After taking 30 doses of Chinese medicines orally, breast lump disappears.

Model case 6

Liu XX, female, 34 years old, Hunan Yongxing County just Jiang Zhen resident, accessible boundary not very clear plump body of gland, there is tenderness, More with the moon premenstrual distending pain and paramenia.Pathological characteristic is that lobular hyperplasia increases increase, boundary clear, existing thin inside and outside leaflet Born of the same parents infiltrate.After taking ten doses of Chinese medicines orally, distending pain of the breast disappears, and energy takes a turn for the better.After taking 30 doses of Chinese medicines orally, breast lump disappears.

Model case 7

Normal XX, female, 50 years old, Changsha City, Hunan Province resident, bilateral breast had lump, be in granular form with streak thing, it is softer, it is seen that Attached breast, no distending pain of the breast and discomfort.After taking 30 doses of Chinese medicines orally, breast lump disappears.

5th, embodiment

Embodiment 1

Pharmaceutical composition decoction of the present invention

Compositions of getting it filled collect immersion liquid after adding constant decocting, add water and are repeated once pan-fried, immersion liquid mixing bottling, and patient is daily Take at twice after meal.

Embodiment 2

Drug composition oral liquid of the present invention

Compositions of getting it filled collect immersion liquid after adding constant decocting, add water be repeated once it is pan-fried, immersion liquid mixing concentration, be routinely made Oral liquid is bottled, and patient takes at twice after meal daily.

Embodiment 3

Medicament composition capsule agent of the present invention

Compositions of getting it filled collect immersion liquid after adding constant decocting, add water be repeated once it is pan-fried, immersion liquid mixing be condensed into medicinal extract, pelletize 20 mesh, it is encapsulated, capsule is made, every 0.4 gram of capsule, is 10 grams of crude drug.Patient takes in three times after meal daily, and every time 10 Grain, takes, 15 tablets each time at twice after meal daily.

Embodiment 4

Medicinal composition tablets of the present invention

Compositions of getting it filled collect immersion liquid after adding the decocting of constant, add water be repeated once it is pan-fried, immersion liquid mixing be condensed into medicinal extract, it is whole 20 mesh of grain, tabletting are made tablet, and every 0.4 gram is containing 10 grams of crude drug.Patient takes at twice after meal daily, 15 every time, daily Take in three times after meal, 10 tablets once.

Embodiment 5

Medicament composition granule agent of the present invention

Compositions of getting it filled collect immersion liquid after adding the decocting of constant, add water be repeated once it is pan-fried, immersion liquid mixing be condensed into medicinal extract, it is whole 20 mesh of grain, into granule.It is containing 100 grams of crude drug often to wrap 10 grams.Patient takes at twice after meal daily, every time 1.5 bag, per natural gift three Secondary clothes, 1 wrap every time.

Drug composition oral liquid of the present invention, granule, the implementation mode of operation of tablet are same as above.

Claims

1. a kind of pharmaceutical composition for treating the proliferation of mammary gland of the present invention and preparation method thereof, mainly by the pharmaceutical composition Radix Astragali, Turpentine, cedar sawdust（China fir）, Ligusticum wallichii, Radix Angelicae Sinensis, cultivated land, return tail, safflower, peach kernel, the red sage root, the radix paeoniae rubrathe, interior gold, hawthorn, Rhizoma Sparganii, cowherb Art, pseudo-ginseng, radix scrophulariae, earthworm, the root of Chinese clematis or the preparation that can be pharmaceutically prepared with auxiliary material.

2. a kind of pharmaceutical composition for treating the proliferation of mammary gland of requirement 1 according to right and preparation method thereof, the medicine be with Lower raw material component：Described pharmaceutical composition parts by weight of raw materials component is 5-400 parts of the Radix Astragali, 5-100 parts of turpentine, China fir Bits（China fir）5-100 parts, 5-100 parts of Ligusticum wallichii, 5-100 parts of Radix Angelicae Sinensis, 5-100 parts of cultivated land, return 5-100 parts of tail, safflower 5- 100 parts, 5-100 parts of peach kernel, 5-100 parts of the red sage root, 5-100 parts of the radix paeoniae rubrathe, interior golden 5-100 parts, 5-100 parts of hawthorn, Rhizoma Sparganii 5-100 parts, 5-100 parts of curcuma zedoary, 5-100 parts of pseudo-ginseng, 5-100 parts of radix scrophulariae, 5-100 parts of earthworm, 5-100 parts of the root of Chinese clematis.

3. a kind of pharmaceutical composition for treating the proliferation of mammary gland according to claim 1,2 and preparation method thereof, the medicine refers to Orally formulation is given described in any pharmacy：Oral liquid, granule, capsule, tablet, effervescent tablet etc..

4. a kind of pharmaceutical composition for treating the proliferation of mammary gland according to claim 1,2,3 and preparation method thereof, including following step Suddenly：Get it filled compositions decocting, then prepared by medicament common method.

5. a kind of pharmaceutical composition for treating the proliferation of mammary gland according to claim 1,2,3,4 and preparation method thereof, the medicine Composition is pharmaceutical composition or wild and plantation pharmaceutical composition of the Market of Chinese Materia Medica through processing.

6. a kind of pharmaceutical composition for treating the proliferation of mammary gland according to claim 1,2,3,4,5 and preparation method thereof, mainly There is the preparation that following raw material is prepared into：150 parts of the Radix Astragali, 10 parts of turpentine, cedar sawdust（China fir）10 parts, 50 parts of Ligusticum wallichii, when Return 20 parts, 20 parts of cultivated land, return 50 parts of tail, 10 parts of safflower, 20 parts of peach kernel, 20 parts of the red sage root, 20 parts of the radix paeoniae rubrathe, interior golden 20 parts, hawthorn 20 Part, 20 parts of Rhizoma Sparganii, 20 parts of curcuma zedoary, 20 parts of pseudo-ginseng, 20 parts of radix scrophulariae, 20 parts of earthworm, 50 parts of the root of Chinese clematis.

, can be with 7. a kind of pharmaceutical composition for treating the proliferation of mammary gland according to claim 1,2,3,4,5,6 and preparation method thereof Be it is dialectical treat, by the reinforcings such as radix scrophulariae 5g -1000g and other blood circulation promoting and enrichings, tonifying middle-Jiao and Qi, kidney and spleen invigorating stomach, softening hardness and resolving stasis give birth to Power is ordered, strengthens the viable organism energy, the prescription Chinese herbal medicine composition of adjustment life organic whole balance.

8. described in a kind of pharmaceutical composition for treating the proliferation of mammary gland according to claim 1,2,3,4,5,6,7 and preparation method thereof Raw material components can be it is dialectical treat, by pharmaceutical composition and other blood circulation promoting and enrichings, tonifying middle-Jiao and Qi, kidney and spleen invigorating stomach, softening hard masses Stasis of blood etc. strengthens life power, strengthens the viable organism energy, the prescription Chinese herbal medicine composition of adjustment life organic whole balance.

9. a kind of pharmaceutical composition for treating the proliferation of mammary gland according to right 1,2,3,4,5,6,7 and preparation method thereof, it is combined Thing converts the preparation method of steamed lean pork soup and decoction boiled egg, comprises the following steps：Compositions decocting of getting it filled mixes afterwards twice Closing, convert daily two clothes of steamed lean meat soup or three clothes, compositions of getting it filled add egg decocting twice, and liquid medicine is taken after mixing it with water egg, and daily two Clothes or three clothes.

10. according to a kind of pharmaceutical composition for treating the proliferation of mammary gland for weighing and requiring 9 and preparation method thereof, in pharmaceutical composition base On plinth, except converting plus steaming in clear soup in addition to lean pork soup and decoction boiled egg, the invigorant and prescription Chinese herbal medicine for adding other temperature compensations can also be converted.