CN107669918A - One kind is used to adjust endocrine Chinese herbal medicine health preserving cream taste and preparation method thereof - Google Patents
One kind is used to adjust endocrine Chinese herbal medicine health preserving cream taste and preparation method thereof Download PDFInfo
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- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract
The invention belongs to health care product field, and in particular to a kind of Chinese herbal medicine health preserving cream taste for having regulation endocrine, improving climacteric malaise symptoms and preparation method thereof.Include the raw material of following parts by weight:10~40 parts of wheat, 10~40 parts of jujube, 5~20 parts of matrimony vine, 6~18 parts of radix polygonati officinalis, 5~15 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 8~25 parts of hawthorn, 5~15 parts of rose, 8~18 parts of dried orange peel, 6~18 parts of radix glycyrrhizae.No matter pharmacological effect and clinical trial show that the scientific and reasonable of this formula, efficacy effect are definite to the present invention, and raw materials used is integration of drinking and medicinal herbs product, fill up the endocrine functional food blank of the daily health regulation of the traditional Chinese medical science.
Description
Technical field
The invention belongs to health care product field, and in particular to one kind has regulation endocrine, improves climacteric uncomfortable diseases
Chinese herbal medicine health preserving cream taste of shape and preparation method thereof.
Background technology
With the quickening of social development speed, modern life, operating pressure are increasing, and endocrinopathy problem is increasingly
Highlight, day reaches regulation endocrine purpose usually through health care and also causes concern.And currently used for diet and professional
It is actually rare to adjust endocrine health care product.
Patent 200710115218.1 discloses a kind of using the treatment neurasthenia such as cultivated land, dogwood fruit, Huai wheat, Chinese yam
Herbal cuisine, the herbal cuisine uses the method that direct decoct soup is eaten, and the active ingredient of decoction medicine, which is not easy to cook, to be come, it is impossible to fully profit
With therapeutic effect is poor.Patent 201410632533.1 is disclosed using the taste of stalk of Fructus Lycii, the Radix Astragali, jujube, chrysanthemum, rose etc. 25
Medlar health preserving health protection tea made of Chinese medicine, the health-care tea directly brew, although directly brewing when taking conveniently,
It is that active ingredient is not to be easy to bubble out, wastes the natural resources of Chinese medicinal materials of preciousness to a certain extent.Patent 201610400245
.2 disclose a kind of method for preparing medicinal extract, this method for solve traditional water decoction boil technique preparation time is long, it is big to obtain medicinal extract amount,
The characteristics of extracts active ingredients are insufficient;The all uses of health maintenance formula disclosed in the first two are directly brewed in above-mentioned patent or decoct soup is eaten
With the active ingredient of medicine can not make full use of, and disclosed in the .2 of patent 201610400245 and prepare graininess blood circulation and channel invigorating
The method of preparation, it is necessary to add various auxiliary materials, finally give for particle, capsule or tablet Chinese patent drug, although the Chinese patent drug takes
With convenient, but because with the addition of more auxiliary material on the composition of the medicine, therefore side effect also accordingly can be more greatly.
It is Chinese medicine conventional dosage forms that cream, which is grown, in good taste because its is convenient to take, is easier to store, especially suitable for that need to adjust for a long time
The crowd of benefit, thus it is deep welcome by numerous people, but the extract grown of conventional pastes is mostly the coarse extraction that decocting is boiled, the production cycle
Long, it is larger that active component recovery rate is low and thermal sensitivity is damaged, and have impact on the effect of cream is grown and plays and quality.
To sum up, it is mostly Chinese patent drug to adjust in the prior art endocrine, and endocrine is long-term chronic disease, conventional medicine
Thing treatment usually has side effect, and there is an urgent need to a kind of pure natural harmless, convenient to take health-preserving food level cream taste.
The content of the invention
Carried out plus be formulated to add according to modern society's health of people feature, nutritional characteristic and product function, and utilize tissue
The Chinese herbal medicine health preserving cream that the extraction of the modern science and technology such as broken, ultrasonic extraction is prepared is grown, by traditional classical with modern science is organic melts
Close, the effect of making Meal regulation, is more notable, improves the medical science health advantage of cream taste, suitable for endocrine disturbance, it is irritated easily
Anger, have no peace of mind, the ordinary meal of the crowd such as night sweat of having a sleepless night is raised, without any artificial addition.The present invention is in solution climacteric
The problem of dyssecretosis, irritability irritability, disclose a kind of for adjusting endocrine Chinese herbal medicine health preserving cream taste and preparation method thereof.
To solve the above problems, the present invention uses following technical scheme:
One kind is used to adjust endocrine Chinese herbal medicine health preserving cream taste, includes the raw material of following parts by weight:10~40 parts of wheat, jujube 10
~40 parts, 5~20 parts of matrimony vine, 6~18 parts of radix polygonati officinalis, 5~15 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 8~25 parts of hawthorn, 5~15 parts of rose, dried orange peel 8
~18 parts, 6~18 parts of radix glycyrrhizae.
Include the raw material of following parts by weight:15~25 parts of wheat, 15~20 parts of jujube, 8~12 parts of matrimony vine, radix polygonati officinalis 10~15
Part, 10~13 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 10~18 parts of hawthorn, 7~12 parts of rose, 10~15 parts of dried orange peel, 8~11 parts of radix glycyrrhizae.
The preparation method grown for adjusting endocrine Chinese herbal medicine health preserving cream, step are as follows:
(1)Raw material is weighed in proportion:Wheat, jujube, matrimony vine, radix polygonati officinalis, FLOS CHRYSANTHEMI ALBA from Haizhou of China, hawthorn, rose, dried orange peel and radix glycyrrhizae, add
Ethanol soaks;
(2)Extracted 3 ~ 4 times using flash extracter, extract 3 ~ 5min every time, merged the filtrate extracted three times, ethanol is recovered under reduced pressure
And it is condensed into dry extract;
(3)By step(2)The dry extract of preparation is placed in ultrasonic extractor, adds ethanol, ultrasonic extraction 3 ~ 6 times, every time 20 ~
40min, filtering is stood, merging filtrate, ethanol is recovered under reduced pressure and is concentrated into clear cream;
(4)By step(3)In clear cream pour into decoction pot, slow fire receives cream to pico- bubbling, adds honey, is stirred continuously, 20 ~
Stop heating after 30min, be fitted into aseptic bottle and seal, complete the preparation that Chinese herbal medicine health preserving cream is grown.
The step(1)In the adding proportion of each raw material be 10~40 parts of wheat, 10~40 parts of jujube, 5~20 parts of matrimony vine,
6~18 parts of radix polygonati officinalis, 5~15 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 8~25 parts of hawthorn, 5~15 parts of rose, 8~18 parts of dried orange peel, 6~18 parts of radix glycyrrhizae;
The addition of ethanol is 7 ~ 15 times of material quality, and soak time is 0.5~1.5h.
The step(3)The addition of middle ethanol is 5 ~ 10 times of medicinal extract quality.
The step(4)The addition of middle honey is 0.5 ~ 2.5 times of clear cream quality.
The Chinese herbal medicine health preserving cream of the present invention nourishes heart and tranquilizing mind relieving restlessness, has regulation endocrine effect, can alleviate and improve climacteric
The symptoms such as phase dysphoria, night sweat, insomnia, do not feel like eating.The present invention is in classical formula " the sweet wheat of Zhang Zhongjing treatment menopause symptom
On the basis of Ziziphi Jujubae Decoction ", according to the health-physical fitness feature of modern people, the effect to help digestion with dispersing stagnated hepatoqi is added, is constituted suitable
The new formula with mental-tranquilization relieving restlessness for modern society.Jujube tonifying spleen and stomach, replenishing qi and blood, tranquilizing mind, there is hypnosis, enhancing
Sleep, protect liver, anti-oxidant and anti-aging effect;Wheat nourishing heart is soothing the liver, except heat, quenches the thirst, arrest sweating;Radix glycyrrhizae tonifying Qi, removing toxic substances, profit
Lung and middle emergency, coordinating the drug actions of a prescription;Matrimony vine tonifying liver kidney yin, improving eyesight, there is the effect such as drop " three high ", anti-oxidant;Radix polygonati officinalis nourishing Yin and moistening lung
Nourishing heart, nourishing the stomach to improve the production of body fluid, there is the effects such as hypoglycemic, anti-lipid, antitumor, anti-mutation;Improving eyesight that chrysanthemum is soothing the liver, clearing heat and detoxicating, tool
There is the effect such as anti-bacteria and anti-virus, antitumor, anti-aging;Hawthorn digesting stomach invigorating, scattered stasis, have and promote digestion, lipid-loweringing, drop
The effect such as pressure, anti-oxidant, anti-cancer;Clearing damp resolving sputum in dried orange peel regulating qi-flowing for strengthening spleen, tune, there is anti-inflammatory antiulcer cholagogic, treatment gastral cavity abdomen gas
Stagnant pain indigestion etc. acts on;Rose is soothing the liver nourishing the stomach, promoting blood circulation for regulating menstruation, resolving stagnation for tranquilization, have chill out, balance in divide
Secrete, replenishing blood and vital energy, relieving mood and have anti-inflammation and sterilization, dispelling fatigue, improve constitution, moist skin etc. effect;Honey bowl spares,
Cough-relieving, moistening dryness for relaxing bowels, removing toxic substances.All medicines are divided the work with monarch, the common effect for completing mental-tranquilization relieving restlessness.
The beneficial effects of the present invention are:
1. formula innovation:The present invention is on the basis of the classical formula " ganmai dazao decoction " of Zhang Zhongjing treatment menopause symptom, according to existing
For the health-physical fitness feature of people, the effect to help digestion with dispersing stagnated hepatoqi is added, constitutes the health guarantor suitable for modern society
Strong new formula.
2. process innovation:Conventional pastes grow it is more boil extraction crude extract using traditional water decoction and formed through enduring cream refining, it is active into
Divide recovery rate low and the production cycle is grown(Once extraction needs 1-2 days time).This method makes full use of modern science and technology, integrates base
In " flash extracter " of historrhexis's principle(Complete once extraction and need only to 30 min), ultrasonic extractor(Complete once
Extraction needs 20-40 min)Deng equipment, the production cycle is shortened to greatest extent, and active component recovery rate is high and concentrates, and carries
The effect of high cream is grown and quality.
No matter 3. pharmacological effect and clinical trial show that the scientific and reasonable of this formula, efficacy effect are definite to the present invention, institute
It is integration of drinking and medicinal herbs product with raw material, fills up the daily health of the traditional Chinese medical science and adjust endocrine functional food blank.
Embodiment
One kind is used to adjust endocrine Chinese herbal medicine health preserving cream taste, includes the raw material of following parts by weight:10~40 parts of wheat, greatly
10~40 parts of jujube, 5~20 parts of matrimony vine, 6~18 parts of radix polygonati officinalis, 5~15 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 8~25 parts of hawthorn, 5~15 parts of rose are old
8~18 parts of skin, 6~18 parts of radix glycyrrhizae.
Include the raw material of following parts by weight:15~25 parts of wheat, 15~20 parts of jujube, 8~12 parts of matrimony vine, radix polygonati officinalis 10~15
Part, 10~13 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 10~18 parts of hawthorn, 7~12 parts of rose, 10~15 parts of dried orange peel, 8~11 parts of radix glycyrrhizae.
The preparation method grown for adjusting endocrine Chinese herbal medicine health preserving cream, step are as follows:
(1)Raw material is weighed in proportion:Wheat, jujube, matrimony vine, radix polygonati officinalis, FLOS CHRYSANTHEMI ALBA from Haizhou of China, hawthorn, rose, dried orange peel and radix glycyrrhizae, add
Ethanol soaks;
(2)Extracted 3 ~ 4 times using flash extracter, extract 3 ~ 5min every time, merged the filtrate extracted three times, ethanol is recovered under reduced pressure
And it is condensed into dry extract;
(3)By step(2)The dry extract of preparation is placed in ultrasonic extractor, adds ethanol, ultrasonic extraction 3 ~ 6 times, every time 20 ~
40min, filtering is stood, merging filtrate, ethanol is recovered under reduced pressure and is concentrated into clear cream;
(4)By step(3)In clear cream pour into decoction pot, slow fire receives cream to pico- bubbling, adds honey, is stirred continuously, 20 ~
Stop heating after 30min, be fitted into aseptic bottle and seal, complete the preparation that Chinese herbal medicine health preserving cream is grown.
The step(1)In the adding proportion of each raw material be 10~40 parts of wheat, 10~40 parts of jujube, 5~20 parts of matrimony vine,
6~18 parts of radix polygonati officinalis, 5~15 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 8~25 parts of hawthorn, 5~15 parts of rose, 8~18 parts of dried orange peel, 6~18 parts of radix glycyrrhizae;
The addition of ethanol is 7 ~ 15 times of material quality, and soak time is 0.5~1.5h.
The step(3)The addition of middle ethanol is 5 ~ 10 times of medicinal extract quality.
The step(4)The addition of middle honey is 0.5 ~ 2.5 times of clear cream quality.
Explanation is further explained to the present invention with reference to specific embodiment:
Embodiment 1
It is a kind of to be used to adjust the preparation process that endocrine Chinese herbal medicine health preserving cream is grown:
Weigh raw material:10 parts of wheat, 40 parts of jujube, 20 parts of matrimony vine, 18 parts of radix polygonati officinalis, 5 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 8 parts of hawthorn, 5 parts of rose,
8 parts of dried orange peel, 6 parts of radix glycyrrhizae;The addition of ethanol is 7 times, soak time 0.5h of material quality, adds 7 times of 50% ethanol
Immersion 0.5, utilize " flash extracter " to extract 3 times, every time extraction 3 minutes, merge filtrate three times, ethanol is recovered under reduced pressure and concentrates
Into dry extract(Calculated yield of weighing is 30%);Medicinal extract is placed in ultrasonic extractor, adds 5 times of 60% EtOH Sonicate to extract 3
It is secondary(Each 20min), filtering is stood, merging filtrate, ethanol is recovered under reduced pressure and is concentrated into clear cream(Proportion is 1.0), clear cream is poured into
In decoction pot, when slow fire receives cream to pico- bubbling, 0.5 times of honey is added, is stirred continuously, refined to heating is stopped during bubbling, fill
Seal and produce in aseptic bottle(Proportion is 1.36).
The effect of following selected part climacteric patient is taken after Chinese herbal medicine health preserving cream is grown is explained,
(1)Health X, sex:Man, age:43 years old, once it was interrupted and takes ten thousand daraf(reciprocal of farad) stars 10mg/ times, daily 1/ time, the past chronic medical history
And infect medical history.
Patient takes the cream time:Amounted to 20 days from 2016-06-06 to 2016-06-26.
Patient takes herbal paste method:Patient takes after Chinese herbal medicine health preserving cream taste 10ml prepared by embodiment 1 adds water to 200ml and drunk,
One time a day.
Patient takes during Chinese herbal medicine health preserving cream is grown and does not take other medicines.
Patient takes main clinical manifestation before Chinese herbal medicine health preserving cream is grown:Endocrine disturbance, irritable, have no peace of mind, have a sleepless night
Easily perspire etc..Have a medical check-up:BP130/90mmHg, 80 beats/min of heart rate, double lungs (-).
Patient takes Chinese herbal medicine health preserving cream and grows main clinical manifestation after January:Insomnia is clearly better, and phychology is gentle, is not easy anger.
Fluctuation of blood pressure is detected during taking cream in 120-130/80-90mmHg or so.
Embodiment 2
It is a kind of to be used to adjust the preparation process that endocrine Chinese herbal medicine health preserving cream is grown:
Weigh raw material:40 parts of wheat, 10 parts of jujube, 5 parts of matrimony vine, 18 parts of radix polygonati officinalis, 5 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 8 parts of hawthorn, 15 parts of rose,
8 parts of dried orange peel, 18 parts of radix glycyrrhizae;The addition of ethanol is 7 times, soak time 1.5h of material quality, adds 15 times of 80% second
Alcohol soaks 0.5h, utilizes " flash extracter " to extract 3 times, every time extraction 5 minutes, merges filtrate three times, ethanol is recovered under reduced pressure simultaneously
It is condensed into dry extract(Calculated yield of weighing is 40%);Medicinal extract is placed in ultrasonic extractor, adds 10 times of 85% EtOH Sonicate
Extraction 6 times(Each 20min), filtering is stood, merging filtrate, ethanol is recovered under reduced pressure and is concentrated into clear cream(Proportion is 1.1), by clear cream
Pour into decoction pot, when slow fire receives cream to pico- bubbling, add 2.5 times of honey, be stirred continuously, refine to stopping during bubbling and add
Heat, fill and seal and produce in aseptic bottle(Proportion is 1.36).
The effect of following selected part climacteric patient is taken after Chinese herbal medicine health preserving cream is grown is explained,
(1)Lee XX, sex:Female, age:45 years old, once it was interrupted and takes alprazolam 10mg/ times, daily 1/ time, the past chronic medical history
And infect medical history.
Patient takes the cream time:Amounted to 2 months from 2016-06-06 to 2016-08-06.
Patient takes herbal paste method:Patient takes after Chinese herbal medicine health preserving cream taste 10ml prepared by embodiment 2 adds water to 100ml and drunk,
One time a day.
Patient takes during Chinese herbal medicine health preserving cream is grown and does not take other medicines.
Patient takes main clinical manifestation before Chinese herbal medicine health preserving cream is grown:Emotional, insomnia, have a headache, be absent minded, more speeches
It is multi-lingual, loudly cry and scream.Have a medical check-up:BP130/100mmHg, 90 beats/min of heart rate, double lungs (-).
Patient takes main clinical manifestation after Chinese herbal medicine health preserving cream is grown 2 months:Phychology is gentle, hardly gets angry, and is emotionally stable.Take cream
Period detects fluctuation of blood pressure in 120-130/80-90mmHg or so.
Embodiment 3
It is a kind of to be used to adjust the preparation process that endocrine Chinese herbal medicine health preserving cream is grown:
Weigh raw material:40 parts of wheat, 30 parts of jujube, 15 parts of matrimony vine, 12 parts of radix polygonati officinalis, 10 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 16 parts of hawthorn, rose 10
Part, 13 parts of dried orange peel, 12 parts of radix glycyrrhizae;The addition of ethanol is 15 times, soak time 1h of material quality, add 11 times 70%
Ethanol immersion 1h, utilize " flash extracter " extract 4 times, every time extraction 5 minutes, merge 4 filtrates, ethanol is recovered under reduced pressure simultaneously
It is condensed into dry extract(Calculated yield of weighing is 40%);Medicinal extract is placed in ultrasonic extractor, adds 8 times of 70% EtOH Sonicate to extract
Take 5 times(Each 30min), filtering is stood, merging filtrate, ethanol is recovered under reduced pressure and is concentrated into clear cream(Proportion is 1.05), by clear cream
Pour into decoction pot, when slow fire receives cream to pico- bubbling, add 1.5 times of honey, be stirred continuously, refine to stopping during bubbling and add
Heat, fill and seal and produce in aseptic bottle(Proportion is 1.41).
The effect of following selected part climacteric patient is taken after Chinese herbal medicine health preserving cream is grown is explained,
(1)Zheng X, sex:Female, age:48 years old, once it was interrupted and takes proxetine hydrochloride tablets 10mg/ times, it is daily 2/ time, previously slow
History of venereal disease and infection medical history.
Patient takes the cream time:January is amounted to from 2016-07-08 to 2016-08-08.
Patient takes herbal paste method:Patient takes after Chinese herbal medicine health preserving cream taste 10ml prepared by embodiment 3 adds water to 150ml and drunk,
2 times a day.
Patient takes during Chinese herbal medicine health preserving cream is grown and does not take other medicines.
Patient takes main clinical manifestation before Chinese herbal medicine health preserving cream is grown:Agitation, anxiety, trouble in mind, even alarmed frightened, note
Recall power decline, be self-doubt.Have a medical check-up:BP130/95mmHg, 100 beats/min of heart rate, double lungs (-).
Patient takes Chinese herbal medicine health preserving cream and grows main clinical manifestation after January:Phychology is gentle, hardly gets angry, and is emotionally stable, memory
Power is remarkably reinforced.Fluctuation of blood pressure is detected during taking cream in 120-125/85-90mmHg or so.
Embodiment 4
It is a kind of to be used to adjust the preparation process that endocrine Chinese herbal medicine health preserving cream is grown:
Weigh raw material:25 parts of wheat, 10 parts of jujube, 20 parts of matrimony vine, 6 parts of radix polygonati officinalis, 15 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 8 parts of hawthorn, rose 15
Part, 8 parts of dried orange peel, 18 parts of radix glycyrrhizae;The addition of ethanol is 15 times, soak time 1.5h of material quality, add 15 times 60%
Ethanol immersion 1h, utilize " flash extracter " to extract 3 times, every time extraction 4 minutes, merge filtrate three times, ethanol is recovered under reduced pressure
And it is condensed into dry extract(Calculated yield of weighing is 35%);Medicinal extract is placed in ultrasonic extractor, adds 8 times of 70% EtOH Sonicate
Extraction 5 times(Each 30min), filtering is stood, merging filtrate, ethanol is recovered under reduced pressure and is concentrated into clear cream(Proportion is 1), clear cream is fallen
Enter in decoction pot, when slow fire receives cream to pico- bubbling, add 2 times of honey, be stirred continuously, refine to heating is stopped during bubbling, fill
Seal and produce in aseptic bottle(Proportion is 1.40).
The effect of following selected part climacteric patient is taken after Chinese herbal medicine health preserving cream is grown is explained,
(1)King X, sex:Female, age:55 years old, once interruption take Sulpiride 10mg/ time, daily 1/ time, the past chronic medical history and
Infect medical history.
Patient takes the cream time:January is amounted to from 2016-07-08 to 2016-08-08.
Patient takes herbal paste method:Patient takes after Chinese herbal medicine health preserving cream taste 20ml prepared by embodiment 4 adds water to 150ml and drunk,
2 times a day.
Patient takes during Chinese herbal medicine health preserving cream is grown and does not take other medicines.
Patient takes main clinical manifestation before Chinese herbal medicine health preserving cream is grown:Insomnia, headache, absent minded, trouble in mind, very
To alarmed frightened, failure of memory.Have a medical check-up:BP130/95mmHg, 100 beats/min of heart rate, double lungs (-).
Patient takes Chinese herbal medicine health preserving cream and grows main clinical manifestation after January:Head does not ache, and insomnia mitigates, and phychology is gentle, seldom
Anger, memory are remarkably reinforced.Fluctuation of blood pressure is detected during taking cream in 120-125/85-90mmHg or so.
Embodiment 5
It is a kind of to be used to adjust the preparation process that endocrine Chinese herbal medicine health preserving cream is grown:
Weigh raw material:25 parts of wheat, 30 parts of jujube, 15 parts of matrimony vine, 12 parts of radix polygonati officinalis, 7 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 16 parts of hawthorn, rose 8
Part, 9 parts of dried orange peel, 12 parts of radix glycyrrhizae;The addition of ethanol is 11 times, soak time 1.2h of material quality, add 9 times 70%
Ethanol immersion 1.2h, utilize " flash extracter " to extract 3 times, every time extraction 5 minutes, merge filtrate three times, second is recovered under reduced pressure
Alcohol is simultaneously condensed into dry extract(Calculated yield of weighing is 40%);Medicinal extract is placed in ultrasonic extractor, adds 10 times of 75% ethanol
Ultrasonic extraction 6 times(Each 30min), filtering is stood, merging filtrate, ethanol is recovered under reduced pressure and is concentrated into clear cream(Proportion is 1.1), will
Clear cream is poured into decoction pot, when slow fire receives cream to pico- bubbling, is added 2.4 times of honey, is stirred continuously, and is refined to stopping during bubbling
Heat, seal and produce in dress aseptic bottle(Proportion is 1.46).
The effect of following selected part climacteric patient is taken after Chinese herbal medicine health preserving cream is grown is explained,
Liu X, sex:Female, age:48 years old, once interruption take stable 10mg/ time, daily 1/ time, the past chronic medical history and infectious disease
History.
Patient takes the cream time:Amounted to 2 months from 2016-03-08 to 2016-05-08.
Patient takes herbal paste method:Patient takes after Chinese herbal medicine health preserving cream taste 20ml prepared by embodiment 5 adds water to 100ml and drunk,
2 times a day.
Patient takes during Chinese herbal medicine health preserving cream is grown and does not take other medicines.
Patient takes main clinical manifestation before Chinese herbal medicine health preserving cream is grown:Mood is irritated, emotional, insomnia, headache, notice not
Concentrate.Have a medical check-up:BP130/95mmHg, 100 beats/min of heart rate, double lungs (-).
Patient takes main clinical manifestation after Chinese herbal medicine health preserving cream is grown 2 months:It is emotionally stable, insomnia mitigates, and phychology is gentle, seldom
Anger, notice are substantially concentrated.Fluctuation of blood pressure is detected during taking cream in 120-125/85-90mmHg or so.
Embodiment 6
It is a kind of to be used to adjust the preparation process that endocrine Chinese herbal medicine health preserving cream is grown:
Weigh raw material:25 parts of wheat, 35 parts of jujube, 17 parts of matrimony vine, 12 parts of radix polygonati officinalis, 11 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 22 parts of hawthorn, rose 12
Part, 14 parts of dried orange peel, 15 parts of radix glycyrrhizae;The addition of ethanol is 12 times, soak time 1.3h of material quality, add 9 times 70%
Ethanol immersion 1.3h, utilize " flash extracter " extract 4 times, every time extraction 5 minutes, merge 4 filtrates, ethanol is recovered under reduced pressure
And it is condensed into dry extract(Calculated yield of weighing is 30%~40%);Medicinal extract is placed in ultrasonic extractor, adds 8 times of 75% second
Alcohol ultrasonic extraction 5 times(Each 35min), filtering is stood, merging filtrate, ethanol is recovered under reduced pressure and is concentrated into clear cream(Proportion is 1.0),
Clear cream is poured into decoction pot, when slow fire receives cream to pico- bubbling, 1.8 times of honey is added, is stirred continuously, is refined to stopping during bubbling
Only heat, seal and produce in dress aseptic bottle(Proportion is 1.4).
The effect of following selected part climacteric patient is taken after Chinese herbal medicine health preserving cream is grown is explained:
Wu XX, sex:Female, age:50 years old, once interruption take stable 10mg/ time, daily 1/ time, the past chronic medical history and infection
Medical history.
Patient takes the cream time:March is amounted to from 2016-02-08 to 2016-05-08.
Patient takes herbal paste method:Patient takes after Chinese herbal medicine health preserving cream taste 20ml prepared by embodiment 6 adds water to 100ml and drunk,
2 times a day.
Patient takes during Chinese herbal medicine health preserving cream is grown and does not take other medicines.
Patient takes main clinical manifestation before Chinese herbal medicine health preserving cream is grown:Mood agitation, anxiety, trouble in mind, emotional, mistake
Sleep, have a headache, be absent minded.Have a medical check-up:BP130/95mmHg, 100 beats/min of heart rate, double lungs (-).
Patient takes Chinese herbal medicine health preserving cream and grows main clinical manifestation after March:It is emotionally stable, insomnia mitigates, and phychology is gentle, seldom
Anger, notice are substantially concentrated.Fluctuation of blood pressure is detected during taking cream in 120-125/90mmHg or so.
Embodiment 7
It is a kind of to be used to adjust the preparation process that endocrine Chinese herbal medicine health preserving cream is grown:
Weigh raw material:30 parts of wheat, 20 parts of jujube, 15 parts of matrimony vine, 14 parts of radix polygonati officinalis, 13 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 19 parts of hawthorn, rose 12
Part, 14 parts of dried orange peel, 16 parts of radix glycyrrhizae;The addition of ethanol is 12 times, soak time 1.3h of material quality, adds 12 times
70% ethanol soaks 1.4 h, utilizes " flash extracter " to extract 4 times, every time extraction 4 minutes, merges 4 filtrates, is recovered under reduced pressure
Ethanol is simultaneously condensed into dry extract(Calculated yield of weighing is 32%);Medicinal extract is placed in ultrasonic extractor, adds 7 times of 69% ethanol
Ultrasonic extraction 4 times(Each 30min), filtering is stood, merging filtrate, ethanol is recovered under reduced pressure and is concentrated into clear cream(Proportion is 1.05),
Clear cream is poured into decoction pot, when slow fire receives cream to pico- bubbling, 1.7 times of honey is added, is stirred continuously, is refined to stopping during bubbling
Only heat, seal and produce in dress aseptic bottle(Proportion is 1.39).
The effect of following selected part climacteric patient is taken after Chinese herbal medicine health preserving cream is grown is explained:
Wu XX, sex:Female, age:50 years old, once interruption take buspirone 10mg/ time, daily 1/ time, the past chronic medical history and
Infect medical history.
Patient takes the cream time:March is amounted to from 2016-02-08 to 2016-05-08.
Patient takes herbal paste method:Patient takes after Chinese herbal medicine health preserving cream taste 20ml prepared by embodiment 7 adds water to 100ml and drunk,
2 times a day.
Patient takes during Chinese herbal medicine health preserving cream is grown and does not take other medicines.
Patient takes main clinical manifestation before Chinese herbal medicine health preserving cream is grown:Say multi-lingual, anxiety, trouble in mind more, loudly cry and scream, lose
Sleep, have a headache, be absent minded.Have a medical check-up:BP130/95mmHg, 100 beats/min of heart rate, double lungs (-).
Patient takes Chinese herbal medicine health preserving cream and grows main clinical manifestation after March:Hardly get angry, phychology is gentle, is emotionally stable, and pays attention to
Power is substantially concentrated.Fluctuation of blood pressure is detected during taking cream in 120-125/90mmHg or so.
Embodiment 8
It is a kind of to be used to adjust the preparation process that endocrine Chinese herbal medicine health preserving cream is grown:
Weigh raw material:29 parts of wheat, 28 parts of jujube, 17 parts of matrimony vine, 15 parts of radix polygonati officinalis, 5 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 8 parts of hawthorn, rose 15
Part, 8 parts of dried orange peel, 6 parts of radix glycyrrhizae;The addition of ethanol is 14 times, soak time 0.8h of material quality, add 7 times 80%
Ethanol soaks 1.5h, utilizes " flash extracter " to extract 3 times, every time extraction 5 minutes, merges filtrate three times, ethanol is recovered under reduced pressure
And it is condensed into dry extract(Calculated yield of weighing is 40%);Medicinal extract is placed in ultrasonic extractor, adds 5 times of 60% EtOH Sonicate
Extraction 5 times(20~40min every time), filtering is stood, merging filtrate, ethanol is recovered under reduced pressure and is concentrated into clear cream(Proportion is 1.0), will
Clear cream is poured into decoction pot, when slow fire receives cream to pico- bubbling, is added 1.8 times of honey, is stirred continuously, and is refined to stopping during bubbling
Heat, seal and produce in dress aseptic bottle(Proportion is 1.46).
The effect of following selected part climacteric patient is taken after Chinese herbal medicine health preserving cream is grown is explained:
All XX, sex:Man, age:46 years old, once it was interrupted and takes buspirone 10mg/ times, daily 1/ time, previously without chronic medical history
And infect medical history.
Patient takes the cream time:March is amounted to from 2016-05-08 to 2016-08-08.
Patient takes herbal paste method:Patient takes after Chinese herbal medicine health preserving cream taste 20ml prepared by embodiment 8 adds water to 100ml and drunk,
2 times a day.
Patient takes during Chinese herbal medicine health preserving cream is grown and does not take other medicines.
Patient takes main clinical manifestation before Chinese herbal medicine health preserving cream is grown:More irritables, have no peace of mind, have a sleepless night.Have a medical check-up:
BP130/95mmHg, 100 beats/min of heart rate, double lungs (-).
Patient takes Chinese herbal medicine health preserving cream and grows main clinical manifestation after March:Phychology is gentle, is emotionally stable, and insomnia situation improves.
Fluctuation of blood pressure is detected during taking cream in 120-125/90mmHg or so.
Embodiment 9
It is a kind of to be used to adjust the preparation process that endocrine Chinese herbal medicine health preserving cream is grown:
Weigh raw material:31 parts of wheat, 29 parts of jujube, 18 parts of matrimony vine, 15 parts of radix polygonati officinalis, 13 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 23 parts of hawthorn, rose 11
Part, 14 parts of dried orange peel, 11 parts of radix glycyrrhizae;The addition of ethanol is 10 times, soak time 1.2h of material quality, adds 13 times
70% ethanol immersion 1.3h, utilizes " flash extracter " to extract 4 times, every time extraction 3 minutes, merges 4 filtrates, be recovered under reduced pressure
Ethanol is simultaneously condensed into dry extract(Calculated yield of weighing is 37.9%);Medicinal extract is placed in ultrasonic extractor, adds 6 times of 85% second
Alcohol ultrasonic extraction 3 times(Each 30min), filtering is stood, merging filtrate, ethanol is recovered under reduced pressure and is concentrated into clear cream(Proportion is 1.0),
Clear cream is poured into decoction pot, when slow fire receives cream to pico- bubbling, 2.3 times of honey is added, is stirred continuously, is refined to stopping during bubbling
Only heat, seal and produce in dress aseptic bottle(Proportion is 1.39).
The effect of following selected part climacteric patient is taken after Chinese herbal medicine health preserving cream is grown is explained:
Zhao XX, sex:Female, age:49 years old, other medicines are not taken, previously without chronic medical history and infection medical history.
Patient takes the cream time:April is amounted to from 2016-02-08 to 2016-06-08.
Patient takes herbal paste method:Patient takes after Chinese herbal medicine health preserving cream taste 20ml prepared by embodiment 7 adds water to 100ml and drunk,
2 times a day.
Patient takes during Chinese herbal medicine health preserving cream is grown and does not take other medicines.
Patient takes main clinical manifestation before Chinese herbal medicine health preserving cream is grown:Insomnia, have a headache, be self-doubt, being slow in action.Have a medical check-up:
BP130/95mmHg, 100 beats/min of heart rate, double lungs (-).
Patient takes Chinese herbal medicine health preserving cream and grows main clinical manifestation after March:Sleep quality is good, headache mitigates, freedom of movement.Clothes
Fluctuation of blood pressure is detected during cream in 120-125/90mmHg or so.
Embodiment 10
It is a kind of to be used to adjust the preparation process that endocrine Chinese herbal medicine health preserving cream is grown:
Weigh raw material:29 parts of wheat, 18 parts of jujube, 9 parts of matrimony vine, 11 parts of radix polygonati officinalis, 12 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 24 parts of hawthorn, rose 13
Part, 16 parts of dried orange peel, 13 parts of radix glycyrrhizae;The addition of ethanol is 11 times, soak time 1h of material quality, add 12 times 60%
Ethanol immersion 1.2h, utilize " flash extracter " to extract 3 times, every time extraction 4 minutes, merge filtrate three times, second is recovered under reduced pressure
Alcohol is simultaneously condensed into dry extract(Calculated yield of weighing is 37%);Medicinal extract is placed in ultrasonic extractor, adds 6 times of 75% ethanol to surpass
Sound extracts 4 times(Each 30min), filtering is stood, merging filtrate, ethanol is recovered under reduced pressure and is concentrated into clear cream(Proportion is 1.0), will be clear
Cream is poured into decoction pot, when slow fire receives cream to pico- bubbling, is added 1.5 times of honey, is stirred continuously, and is refined to stopping during bubbling and is added
Heat, fill and seal and produce in aseptic bottle(Proportion is 1.41).
The effect of following selected part climacteric patient is taken after Chinese herbal medicine health preserving cream is grown is explained:
Zhao XX, sex:Female, age:55 years old, other medicines were not taken, suffered from depression.
Patient takes the cream time:December is amounted to from 2016-02-08 to 2017-02-08.
Patient takes herbal paste method:Patient takes after Chinese herbal medicine health preserving cream taste 20ml prepared by embodiment 10 adds water to 150ml and drunk,
2 times a day.
Patient takes during Chinese herbal medicine health preserving cream is grown and does not take other medicines.
Patient takes main clinical manifestation before Chinese herbal medicine health preserving cream is grown:Slight forgetful, headache, poor appetite.Have a medical check-up:BP130/
95mmHg, 100 beats/min of heart rate, double lungs (-).
Patient takes Chinese herbal medicine health preserving cream and grows main clinical manifestation after March:Sleep quality is good, have a headache mitigation, freedom of movement, drink
Food is normal.Fluctuation of blood pressure is detected during taking cream in 120-125/90mmHg or so.
Claims (6)
1. one kind is used to adjust endocrine Chinese herbal medicine health preserving cream taste, it is characterised in that includes the raw material of following parts by weight:Wheat 10
~40 parts, 10~40 parts of jujube, 5~20 parts of matrimony vine, 6~18 parts of radix polygonati officinalis, 5~15 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 8~25 parts of hawthorn, rose 5
~15 parts, 8~18 parts of dried orange peel, 6~18 parts of radix glycyrrhizae.
2. as claimed in claim 1 be used to adjust endocrine Chinese herbal medicine health preserving cream taste, it is characterised in that including following parts by weight
Raw material:15~25 parts of wheat, 15~20 parts of jujube, 8~12 parts of matrimony vine, 10~15 parts of radix polygonati officinalis, 10~13 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, hawthorn
10~18 parts, 7~12 parts of rose, 10~15 parts of dried orange peel, 8~11 parts of radix glycyrrhizae.
3. as claimed in claim 1 or 2 be used to adjust the preparation method that endocrine Chinese herbal medicine health preserving cream is grown, it is characterised in that
Step is as follows:
(1)Raw material is weighed in proportion:Wheat, jujube, matrimony vine, radix polygonati officinalis, FLOS CHRYSANTHEMI ALBA from Haizhou of China, hawthorn, rose, dried orange peel and radix glycyrrhizae, add
Ethanol soaks;
(2)Extracted 3 ~ 4 times using flash extracter, extract 3 ~ 5min every time, merged the filtrate extracted three times, ethanol is recovered under reduced pressure
And it is condensed into dry extract;
(3)By step(2)The dry extract of preparation is placed in ultrasonic extractor, adds ethanol, ultrasonic extraction 3 ~ 6 times, every time 20 ~
40min, filtering is stood, merging filtrate, ethanol is recovered under reduced pressure and is concentrated into clear cream;
(4)By step(3)In clear cream pour into decoction pot, slow fire receives cream to pico- bubbling, adds honey, is stirred continuously, 20 ~
Stop heating after 30min, be fitted into aseptic bottle and seal, complete the preparation that Chinese herbal medicine health preserving cream is grown.
4. as claimed in claim 3 be used to adjust the preparation method that endocrine Chinese herbal medicine health preserving cream is grown, it is characterised in that:It is described
Step(1)In the adding proportion of each raw material be 10~40 parts of wheat, 10~40 parts of jujube, 5~20 parts of matrimony vine, 6~18 parts of radix polygonati officinalis,
5~15 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 8~25 parts of hawthorn, 5~15 parts of rose, 8~18 parts of dried orange peel, 6~18 parts of radix glycyrrhizae;The addition of ethanol
For 7 ~ 15 times of material quality, soak time is 0.5~1.5h.
5. as claimed in claim 3 be used to adjust the preparation method that endocrine Chinese herbal medicine health preserving cream is grown, it is characterised in that:It is described
Step(3)The addition of middle ethanol is 5 ~ 10 times of dry extract quality.
6. as claimed in claim 3 be used to adjust the preparation method that endocrine Chinese herbal medicine health preserving cream is grown, it is characterised in that:It is described
Step(4)The addition of middle honey is 0.5 ~ 2.5 times of clear cream quality.
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CN108888722A (en) * | 2018-08-13 | 2018-11-27 | 河南中医药大学 | A kind of integration of drinking and medicinal herbs Chinese medicine jujube with treatment insomnia of calming the nerves is soothed the spirit particle |
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