CN107669916A - Sophora bud oral liquid and preparation method thereof - Google Patents

Sophora bud oral liquid and preparation method thereof Download PDF

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Publication number
CN107669916A
CN107669916A CN201711198174.3A CN201711198174A CN107669916A CN 107669916 A CN107669916 A CN 107669916A CN 201711198174 A CN201711198174 A CN 201711198174A CN 107669916 A CN107669916 A CN 107669916A
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Prior art keywords
parts
sophora bud
oral liquid
liquid according
bud oral
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Inventor
付平国
刘文瑞
欧玉莲
王建买
付嫦娥
刘小军
欧召国
付玉香
李凯
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Hengyang Huashengda Forestry Science And Technology Co Ltd
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Hengyang Huashengda Forestry Science And Technology Co Ltd
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Priority to CN201711198174.3A priority Critical patent/CN107669916A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/28—Mercury; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • A61K35/10—Peat; Amber; Turf; Humus
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/37—Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/69—Polygalaceae (Milkwort family)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888—Pinellia
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966—Fritillaria, e.g. checker lily or mission bells
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    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

A kind of sophora bud oral liquid, it is characterised in that in terms of parts by weight, be made up of following material composition：100 parts of the sophora bud, 10 30 parts of radix glehniae, 10 20 parts of calamus, 5 10 parts of folium cortex eucommiae, 10 20 parts of the tuber of pinellia, 5 20 parts of tendril-leaved fritillary bulb, 10 30 parts of rhizoma Gastrodiae, 10 15 parts of Glabrous Sarcandra Herb, 10 20 parts of stiff silkworm, 10 20 parts of semen astragali complanati, 5 15 parts of amber, 10 30 parts of cinnabar, 5 15 parts of fushen, 5 15 parts of polygala, 10 30 parts of selaginella doederlleini, 10 30 parts of Agrimony, 10 30 parts of climbing groundsel, 10 30 parts of datura flower, 10 30 parts of smallflower milkwort herb with root, 5 15 parts of celastrus orbiculatus；The sophora bud oral liquid can treat diabetes.

Description

Sophora bud oral liquid and preparation method thereof
Technical field
The invention belongs to technical field of Chinese medicine, and in particular to a kind of sophora bud oral liquid and preparation method thereof.
Background technology
There are nearly 20 kinds of a Chinese scholartree, needle Chinese scholartree, Huang Huai, beans Chinese scholartree, golden Chinese scholartree etc. in China, using golden Chinese scholartree to be best, because color is in gold Yellow and gain the name, its plant of yield maximum, rutin content highest, the grain of rice is big and real, so being acknowledged as the top grade in the sophora bud.
Golden Chinese scholartree complete stool can be used as medicine, and the sophora bud receives sword hemostatic, and hypotensive to be cooling；Fruit heat-clearing, moisten liver, cool blood, stop Blood；The sophora bud is the drying flower or bud of Chinese scholartree, and summer flower is plucked open, stored up after drying, be available for annual use；The sophora bud has Cooling blood and hemostasis, the function of clearing liver-fire；The treatment of the diseases such as clinic is used for having blood in stool, hemorrhoid blood, bloody flux, uterine bleeding, haematemesis.
Due to effect of the sophora bud to capillary, the normal resistance of capillary can be kept, reduces vasopermeability, can Make blood vessel because fragility increase and the capillary of bleeding recover normal elasticity, therefore have softening blood vessel, increase blood vessel elasticity, to artery Hardening has emollescence, has preventive and therapeutic effect to diabetes, the retinitis；Its preparation, which has, promotes microcirculation, blood fat-reducing blood pressure-decreasing, efficiency drop Low liver, sustainer and blood middle cholesterol content have functions of lowering blood-fat and reducing weight to overweight people；Due to above-mentioned effect, all knowing at all times, Li Shizhen (1518-1593 A.D.)《The careless detailed outline of wood》The healthcare function of ancestors' sophora bud is described already.
Therefore, it is necessary to a kind of sophora bud Chinese medicine composition of healthy treatment diabetes is developed, to control and solve glycosuria The problem of sick colony's blood glucose rise, and can effectively prevent the symptom complex of diabetes.
The content of the invention
It is to provide a kind of sophora bud oral liquid according to technical problem, an object of the present invention existing for current drug rehabilitation, should Sophora bud oral liquid can treat diabetes.
The second object of the present invention is the preparation method for the sophora bud oral liquid for providing the treatment diabetes.
Sophora bud oral liquid of the present invention, in terms of parts by weight, its raw material consists of the following composition：100 parts of the sophora bud, radix glehniae 10-30 parts, calamus 10-20 parts, folium cortex eucommiae 5-10 parts, tuber of pinellia 10-20 parts, tendril-leaved fritillary bulb 5-20 parts, rhizoma Gastrodiae 10-30 parts, Glabrous Sarcandra Herb 10- 15 parts, stiff silkworm 10-20 parts, semen astragali complanati 10-20 parts, amber 5-15 parts, cinnabar 10-30 parts, fushen's 5-15 parts, polygala 5-15 parts, Selaginella doederlleini 10-30 parts, Agrimony 10-30 parts, climbing groundsel 10-30 parts, datura flower 10-30 parts, smallflower milkwort herb with root 10-30 parts, celastrus orbiculatus 5-15 parts.
The preferred 10-20 parts of wherein described radix glehniae.
The preferred 10-15 parts of wherein described calamus.
The preferred 7-10 parts of wherein described folium cortex eucommiae, the preferred 15-20 parts of the tuber of pinellia, the preferred 5-15 parts of tendril-leaved fritillary bulb.
The preferred 10-20 parts of wherein described rhizoma Gastrodiae, the preferred 10-12 parts of Glabrous Sarcandra Herb, the preferred 15-20 parts of stiff silkworm.
The preferred 15-20 parts of wherein described semen astragali complanati, the preferred 5-10 parts of amber, the preferred 10-20 parts of cinnabar.
The preferred 10-15 parts of wherein described fushen, the preferred 5-10 parts of polygala, the preferred 10-20 parts of selaginella doederlleini.
The preferred 15-30 parts of wherein described Agrimony, climbing groundsel are climbing groundsel powder, and preferably 20-30 parts, datura flower is preferred 10-20 parts.
The preferred 20-30 parts of wherein described smallflower milkwort herb with root, the preferred 10-15 parts of celastrus orbiculatus.
The preparation method of the sophora bud oral liquid of present invention treatment diabetes is as follows：
（1）By the sophora bud weighed up, radix glehniae, calamus, folium cortex eucommiae, the tuber of pinellia, tendril-leaved fritillary bulb, rhizoma Gastrodiae, Glabrous Sarcandra Herb, stiff silkworm, semen astragali complanati, Fu God, polygala, selaginella doederlleini, Agrimony, climbing groundsel, datura flower, smallflower milkwort herb with root and celastrus orbiculatus are put into decocting container, add water, boiled Slow fire decocts 20-40 minutes afterwards, maintains boiling water；Wherein the weight ratio of Chinese medicine material and water is 1:（3-5）；
（2）By well-done medical filtration；
（3）Again by the amber of formula ratio and cinnabar powder, add in filtrate, mix, it is filling.
The sophora bud oral liquid of present invention treatment diabetes, warmly takes for daily 2-3 times, each 50-200ml.
Diabetes are caused by the endocrine system disorder of people, are the symptoms showed before serious disease arrives, this disease is simultaneously Non- disease, disease are the tendencys of disease, and disease is the outburst of the comprehensive accumulation of disease, and disease can be eliminated by nursing one's health physical function completely, The root of disease nips in the bud；The sophora bud oral liquid of present invention treatment diabetes improves the anti-of body around this principle Sick ability, the effect that human body autologous stem cells self-replacation is played along internal system function is adjusted, activation and repairing pancreas are thin Born of the same parents, by the factor caused by stem cell, stimulate beta Cell of islet to regenerate, it is recovered the function of excreting insulin, increase is internal Insulin level and balance blood sugar.
The sophora bud oral liquid of present invention treatment diabetes is adapted to that immune power is low, resistance against diseases is poor, weak and sickly, high Blood pressure, high fat of blood, type 1 diabetes and diabetes B patient, can fundamentally treat diabetes.
Embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will Understand, the following example is merely to illustrate the present invention, and should not be taken as limiting the scope of the invention.
Embodiment 1
Table 1 is the raw material proportioning of embodiment 1-6 and comparative example 1.
The embodiment 1-6 of table 1 and comparative example 1 raw material proportioning, gram
。
Comparative example 1 removes radix glehniae for the formula of embodiment 1 in table 1.
Table 2 is embodiment 7-10 and comparative example 2-3 raw material proportioning.
The embodiment 7-10 of table 2 and comparative example 2-3 raw material proportioning, gram
。
Comparative example 2 removes semen astragali complanati for the formula of embodiment 7 in table 2, and comparative example 3 removes southern snake for the formula of embodiment 8 Rattan.
Above example and the preparation method of comparative example oral liquid are as follows：
（1）By the sophora bud weighed up, radix glehniae, calamus, folium cortex eucommiae, the tuber of pinellia, tendril-leaved fritillary bulb, rhizoma Gastrodiae, Glabrous Sarcandra Herb, stiff silkworm, semen astragali complanati, Fu God, polygala, selaginella doederlleini, Agrimony, climbing groundsel, datura flower, smallflower milkwort herb with root and celastrus orbiculatus are put into decocting container, add water, boiled Slow fire is decocted 30 minutes afterwards, maintains boiling water；Wherein the weight ratio of medicine and water is 1:4；
（2）By well-done medical filtration；
（3）Again by the amber of formula ratio and cinnabar powder, filtrate is added, is mixed, it is filling.
It is as follows for above example and comparative example, clinical application effect.
（1）Hyperglycemia patient using effect:
Fasting blood-glucose is more than 6, and postprandial blood sugar is more than or equal to 7.7 can say it is hyperglycaemia, will be not reaching to diabetes standard The people of hyperglycemia patient 260, is equally divided into 13 groups, every group of 20 people, takes embodiment 1-10 and comparative example 1-3 treatment glycosuria respectively The sophora bud oral liquid of disease, 3 times a day, each 70ml), warm water is taken, and 30 days are 1 course for the treatment of, take 4 courses for the treatment of, diet low sugar Diet, after 4 courses for the treatment of, embodiment 1-10 Fasting Glucose and postprandial blood sugar full recovery are normal, and comparative example 1 only has 5 Recover normal, comparative example 2 only has 4 to recover normal, and comparative example 3 only has 5 to recover normal.
（2）Type 1 diabetes people's using effect:
Type 1 diabetes people 130,13 groups are equally divided into, every group of 10 people, takes controlling for embodiment 1-10 and comparative example 1-3 respectively The sophora bud oral liquid of diabetes is treated, 3 times a day, each 70ml, warm water is taken；Average 14.5 mmol/ of these patient's preprandial glucoses L, average 22 mmol/L of postprandial blood sugar, main suit's giddy, tinnitus, uncomfortable in chest, shortness of breath, insomnia, it is double to take antidiabetic drug diformazan 3 times a day Guanidine piece maintains；The effect for taking the sophora bud oral liquid for the treatment of diabetes is shown in Table 3.
Table 3
。
Above content describes the general principle and principal character of the present invention, and the present invention is not limited to the above embodiments, Without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, and these changes and improvements are all Fall into scope of the claimed invention.

Claims (10)

1. a kind of sophora bud oral liquid, it is characterised in that in terms of parts by weight, be made up of following material composition：
100 parts of the sophora bud, radix glehniae 10-30 parts, calamus 10-20 parts, folium cortex eucommiae 5-10 parts, tuber of pinellia 10-20 parts, tendril-leaved fritillary bulb 5-20 parts, Rhizoma Gastrodiae 10-30 parts, Glabrous Sarcandra Herb 10-15 parts, stiff silkworm 10-20 parts, semen astragali complanati 10-20 parts, amber 5-15 parts, cinnabar 10-30 parts, Fu Refreshing 5-15 parts, polygala 5-15 parts, selaginella doederlleini 10-30 parts, Agrimony 10-30 parts, climbing groundsel 10-30 parts, datura flower 10-30 parts, Smallflower milkwort herb with root 10-30 parts, celastrus orbiculatus 5-15 parts.
2. sophora bud oral liquid according to claim 1, it is characterised in that described radix glehniae is 10-20 parts.
3. sophora bud oral liquid according to claim 1, it is characterised in that described calamus is 10-15 parts.
4. sophora bud oral liquid according to claim 1, it is characterised in that described folium cortex eucommiae is 7-10 parts, tuber of pinellia 15- 20 parts, tendril-leaved fritillary bulb is 5-15 parts.
5. sophora bud oral liquid according to claim 1, it is characterised in that described rhizoma Gastrodiae is 10-20 parts, Glabrous Sarcandra Herb 10- 12 parts, stiff silkworm is 15-20 parts.
6. sophora bud oral liquid according to claim 1, it is characterised in that described semen astragali complanati is 15-20 parts, amber 5- 10 parts, cinnabar is 10-20 parts.
7. sophora bud oral liquid according to claim 1, it is characterised in that described fushen is 10-15 parts, polygala 5-10 Part, selaginella doederlleini is 10-20 parts.
8. sophora bud oral liquid according to claim 1, it is characterised in that described Agrimony is 15-30 parts, and climbing groundsel is 20-30 parts, datura flower are 10-20 parts.
9. sophora bud oral liquid according to claim 1, it is characterised in that described smallflower milkwort herb with root is 20-30 parts, and celastrus orbiculatus is 10-15 parts.
10. the preparation method of sophora bud oral liquid according to claim 1, it is characterised in that in turn include the following steps:
（1）The Chinese medicine material sophora bud, radix glehniae, calamus, folium cortex eucommiae, the tuber of pinellia, tendril-leaved fritillary bulb, rhizoma Gastrodiae, Glabrous Sarcandra Herb, stiff silkworm, the sand that will be weighed up Yuan Zi, fushen, polygala, selaginella doederlleini, Agrimony, climbing groundsel, datura flower, smallflower milkwort herb with root and celastrus orbiculatus are put into decocting container, are added Water, boiled rear slow fire are decocted 20-40 minutes, and wherein the weight ratio of Chinese medicine material and water is 1:（3-5）；
（2）By well-done medical filtration；
（3）Again by the amber of formula ratio and cinnabar powder, add in filtrate, mix, it is filling.
CN201711198174.3A 2017-11-25 2017-11-25 Sophora bud oral liquid and preparation method thereof Pending CN107669916A (en)

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CN201711198174.3A CN107669916A (en) 2017-11-25 2017-11-25 Sophora bud oral liquid and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN1232624A (en) * 1998-04-17 1999-10-27 王树义 Health tea and its preparation
CN1754546A (en) * 2004-09-30 2006-04-05 上海方心科技研究所 Traditional Chinese medicine formulation for treating and preventing diabetes and its angiopathy
CN101129987A (en) * 2007-08-29 2008-02-27 北京艺信堂医药研究所 Proprietary Chinese medicine for treating diabetes cerebral apoplexy
CN101904394A (en) * 2010-07-29 2010-12-08 靳维荣 Method for preparing sophora flower bud tea

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1232624A (en) * 1998-04-17 1999-10-27 王树义 Health tea and its preparation
CN1754546A (en) * 2004-09-30 2006-04-05 上海方心科技研究所 Traditional Chinese medicine formulation for treating and preventing diabetes and its angiopathy
CN101129987A (en) * 2007-08-29 2008-02-27 北京艺信堂医药研究所 Proprietary Chinese medicine for treating diabetes cerebral apoplexy
CN101904394A (en) * 2010-07-29 2010-12-08 靳维荣 Method for preparing sophora flower bud tea

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李卫青 等: "《中国糖尿病秘方全书》", 31 October 2002, 科学技术文献出版社 *

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