CN107661453A - A kind of sachet content with rush dormancy effect of calming the nerves - Google Patents
A kind of sachet content with rush dormancy effect of calming the nerves Download PDFInfo
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- CN107661453A CN107661453A CN201711073899.XA CN201711073899A CN107661453A CN 107661453 A CN107661453 A CN 107661453A CN 201711073899 A CN201711073899 A CN 201711073899A CN 107661453 A CN107661453 A CN 107661453A
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/009—Sachets, pouches characterised by the material or function of the envelope
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses a kind of sachet content with rush dormancy effect of calming the nerves, it is related to sachet manufacture technology field, promoted dormancy agent and forming agent by calming the nerves and be made, described calm the nerves promotees dormancy agent comprising vegetable-derived components and synthesizes derived components, vegetable-derived components, synthesis derived components using tablet press machine are pressed into tablet after being mixed in proportion with forming agent, then the particle of the mesh of granularity 40 80 are made through pulverizer.Sachet is made after sachet bag through sewing in the made sachet content of the present invention, sachet is placed at one's side by user during sleep, content persistently gives out one light faint scent, plays and alleviates tired, pneumostatic, abirritative effect with fixed attention, promotees to sleep so as to calm the nerves.
Description
Technical field：
The present invention relates to sachet manufacture technology field, and in particular to a kind of sachet content with rush dormancy effect of calming the nerves.
Background technology：
With the development of society, the quickening of rhythm of life, many people are due to being chronically under nervous and pressure, therefore easily
The problems such as producing insomnia, depression and anxiety obstacle, tension headache, and be often accompanied by mood worry, easily enrage, sleep-disorder, muscle
The symptoms such as tonicity pain.
Usual people select these problems of drug therapy, but prolonged administration of drugs can inevitably bring some pairs to make
With, and easily produce drug tolerance, habituation and additive.
In recent years, health pillow turns into the conventional selection of sleep-disorder person, passes through the taste that contained Chinese medicine gives out in health pillow
Road promotees dormancy effect to play to calm the nerves.But contained Chinese medicine is general up to 10 kinds or more than 10 kinds in health pillow, and its volatile ingredient does not have
Have completely clearly, it is also unknown whether long-term use can produce actual bodily harm to human body.Also, because most of Chinese medicine contains
Carbohydrate content, easy mould growth when long-term use of, so as to cause safe and healthy hidden danger to user.
The content of the invention：
The technical problems to be solved by the invention are to provide a kind of effect notable and efficacy lasting, safe to use
Sachet content with rush dormancy effect of calming the nerves.
The technical problems to be solved by the invention are realized using following technical scheme：
It is a kind of have to calm the nerves promote the sachet content of dormancy effect, promoted dormancy agent and forming agent by calming the nerves and be made, the rush of calming the nerves
Dormancy agent includes vegetable-derived components and synthesis derived components, and vegetable-derived components, synthesis derived components utilize after being mixed in proportion with forming agent
Tablet press machine is pressed into tablet, then the particle of granularity 40-80 mesh is made through pulverizer.
The mass ratio of the vegetable-derived components, synthesis derived components and forming agent is 1-5:0.1-0.5:5-15.
The vegetable-derived components are by mass ratio 2:2:1:1:0.5 Chinese ilex essential oil, cus-cus essential oil, styrax essential oil, Cape jasmine
Sub- flower essential oil, honeysuckle essential oil mix.
The Chinese ilex essential oil, cus-cus essential oil, styrax essential oil, cape jasmine flower essential oil, honeysuckle essential oil are by leaf of Chinese ilex, rock
Fragrant thoroughwort, styrax, gardenia, honeysuckle are made through steam distillation.
One or more of the synthesis derived components in cyclamen aldehyde, bergamot aldehyde, piperonal, myristic aldehyde.
The forming agent is in PVPP, sodium carboxymethylcellulose, microcrystalline cellulose, HPMC
It is one or more of.
The forming agent is made up of the raw material of following parts by weight：
Sensor Chip CM 5 sodium 10-15 parts, hydrophobicity aerosil 5-10 parts, cation guar gum 1-5 parts, nanometer
Titanium dioxide 1-5 parts, rilanit special 0.5-3 parts, trimethylol-propane trimethacrylate 0.5-3 parts, gamma-polyglutamic acid
0.5-3 parts, N hydroxymethyl acrylamide 0.05-2 parts, potassium peroxydisulfate 0.01-0.05 parts, butyl titanate 0.005-0.01 parts；
Its preparation method comprises the following steps：
(1) deionized water is added dropwise until being completely dissolved into Sensor Chip CM 5 sodium under stirring, recycles dust technology regulation
PH value is heated to 60-70 DEG C of insulated and stirred to 3-4, detects a pH value every 5min, dilute nitre is added when pH value is more than 4
Acid so that pH value control in 3-4, when system pH in 15min continually and steadily in 3-4 when add N hydroxymethyl acrylamide, after
It is continuous to be heated to reflux state insulated and stirred 2-5h, trimethylol-propane trimethacrylate and potassium peroxydisulfate are added, again
Flowed back insulated and stirred 1-3h, and gained mixture is sent into spray dryer when naturally cooling to less than 50 DEG C, dries gained particle
Micro mist is made through micronizer, produces water-based glucan-acrylic resin compound；
(2) molten condition insulated and stirred is heated to after mixing cation guar gum, gamma-polyglutamic acid and butyl titanate
1-3h, to weight boiling water such as gained solid additions when naturally cooling to less than 70 DEG C, and it is heated to reflux state insulated and stirred 10-
15min, gained mixture is concentrated to reach 60-70% to solid content, is finally sent into freeze drier, dries gained solid warp
Micro mist is made in micronizer, produces modified guar；
(3) hydrophobicity aerosil, modification are added into above-mentioned made water-based glucan-acrylic resin compound
Guar gum, nano titanium oxide and rilanit special, are sufficiently mixed, and produce slow-released carrier.
The gamma-polyglutamic acid is selected from food-grade gamma-polyglutamic acid.
The rilanit special passes through modification, and its specific method of modifying is：First rilanit special is heated to melting
State insulated and stirred 3-5min, adds trihydroxymethylpropanyltri diglycidyl ether and stearic acid, continues to be heated to 110-120 DEG C
Insulated and stirred 0.5-2h, gained mixture are cooled to 0-5 DEG C of insulation with 5 DEG C/min cooling rate and stand 1-2h, produce modification
Rilanit special.
The rilanit special, trihydroxymethylpropanyltri diglycidyl ether and stearic mass ratio are 5-10:0.5-3:
0.5-3。
Rilanit special significantly increases its performance after above-mentioned modification.
The beneficial effects of the invention are as follows：
(1) present invention is combined as rush dormancy agent of calming the nerves using vegetable-derived components and synthesis derived components, to strengthen its rush of calming the nerves
Dormancy effect；And using forming agent as auxiliary material, promote dormancy agent particulate form to assign calming the nerves, in order to store, while prevent because in
Drug composition promotees problem of easily being gone mouldy existing for dormancy agent as calming the nerves；
(2) forming agent of the present invention has two kinds of selections, and a kind of is the conventional fillers of field of pharmaceutical preparations, to pass through tabletting and powder
Broken technique, which makes to calm the nerves, to be promoted dormancy agent and exists in granular form；Another kind is self-control forming agent, and the self-control forming agent can not only make to calm the nerves
Promote dormancy agent and be changed into particle form, can more assign the excellent slow release effect of rush dormancy agent of calming the nerves, be calmed the nerves by slow releasing function with controlling
Promote the evaporation rate of dormancy agent, so that made sachet content has the characteristics of long-acting rush of calming the nerves is slept；
(3) sachet is made through sewing in the made sachet content of the present invention after sachet bag, and user is during sleep by perfume (or spice)
Capsule is placed at one's side, and content persistently gives out one light faint scent, and performance alleviation is tired, pneumostatic, elimination are nervous with fixed attention
The effect of, promote to sleep so as to calm the nerves, human body is in the tranquil state loosened to rapidly enter sleep, be particularly suitable for use in sleep-disorder
Person.
Embodiment：
In order that the technical means, the inventive features, the objects and the advantages of the present invention are easy to understand, tie below
Specific embodiment is closed, the present invention is expanded on further.
Embodiment 1
It is a kind of have to calm the nerves promote the sachet content of dormancy effect, promoted dormancy agent and forming agent by calming the nerves and be made, the rush of calming the nerves
Dormancy agent includes vegetable-derived components and synthesis derived components, and 2g vegetable-derived components, 0.15g synthesis derived components cyclamen aldehydes and 12g are molded
Tablet is pressed into using tablet press machine after the mixing of agent PVPP, then the particle of the mesh of granularity 60 is made through pulverizer.
Vegetable-derived components are by mass ratio 2:2:1:1:0.5 Chinese ilex essential oil, cus-cus essential oil, styrax essential oil, gardenia
Essential oil, honeysuckle essential oil mix.
Embodiment 2
It is a kind of have to calm the nerves promote the sachet content of dormancy effect, promoted dormancy agent and forming agent by calming the nerves and be made, the rush of calming the nerves
Dormancy agent includes vegetable-derived components and synthesis derived components, 3g vegetable-derived components, 0.3g synthesis derived components cyclamen aldehydes and 15g forming agents
Tablet is pressed into using tablet press machine after sodium carboxymethylcellulose mixing, then the particle of the mesh of granularity 60 is made through pulverizer.
Vegetable-derived components are by mass ratio 2:2:1:1:0.5 Chinese ilex essential oil, cus-cus essential oil, styrax essential oil, gardenia
Essential oil, honeysuckle essential oil mix.
Embodiment 3
It is a kind of have to calm the nerves promote the sachet content of dormancy effect, promoted dormancy agent and forming agent by calming the nerves and be made, the rush of calming the nerves
Dormancy agent includes vegetable-derived components and synthesis derived components, and 2g vegetable-derived components, 0.15g synthesis derived components cyclamen aldehydes and 12g are molded
Tablet is pressed into using tablet press machine after the mixing of agent HPMC, then the particle of the mesh of granularity 60 is made through pulverizer.
Vegetable-derived components are by mass ratio 2:2:1:1:0.5 Chinese ilex essential oil, cus-cus essential oil, styrax essential oil, gardenia
Essential oil, honeysuckle essential oil mix.
Embodiment 4
It is a kind of have to calm the nerves promote the sachet content of dormancy effect, promoted dormancy agent and forming agent by calming the nerves and be made, the rush of calming the nerves
Dormancy agent includes vegetable-derived components and synthesis derived components, 3g vegetable-derived components, 0.3g synthesis derived components cyclamen aldehydes and 15g forming agents
Tablet is pressed into using tablet press machine after mixing, then the particle of the mesh of granularity 60 is made through pulverizer.
Vegetable-derived components are by mass ratio 2:2:1:1:0.5 Chinese ilex essential oil, cus-cus essential oil, styrax essential oil, gardenia
Essential oil, honeysuckle essential oil mix.
The preparation of forming agent：
(1) deionized water is added dropwise until being completely dissolved into 10g Sensor Chip CM 5 sodium under stirring, recycles dust technology to adjust
PH value is saved to 3-4, and is heated to 60-70 DEG C of insulated and stirred, a pH value is detected every 5min, is added when pH value is more than 4 dilute
Nitric acid so that pH value control in 3-4, when system pH in 15min continually and steadily in 3-4 when add 1g N- methylol acryloyls
Amine, continue to be heated to reflux state insulated and stirred 2h, add 2g trimethylol-propane trimethacrylates and 0.05g over cures
Sour potassium, flowed back insulated and stirred 1h again, and gained mixture is sent into spray dryer when naturally cooling to less than 50 DEG C, dries institute
Obtain particle and micro mist is made through micronizer, produce water-based glucan-acrylic resin compound；
(2) it is heated to after mixing 5g cation guar gums, 1g food-grades gamma-polyglutamic acid and 0.01g butyl titanates
Molten condition insulated and stirred 1h, to weight boiling water such as gained solid additions when naturally cooling to less than 70 DEG C, and it is heated to flowing back
State insulated and stirred 15min, gained mixture is concentrated to reach 60-70% to solid content, is finally sent into freeze drier, does
Micro mist is made through micronizer in dry gained solid, produces modified guar；
(3) 5g hydrophobicity aerosils are added into above-mentioned made water-based glucan-acrylic resin compound, are changed
Property guar gum, 3g nano titanium oxides and 1g rilanit specials, are sufficiently mixed, produce forming agent.
Embodiment 5
It is a kind of have to calm the nerves promote the sachet content of dormancy effect, promoted dormancy agent and forming agent by calming the nerves and be made, the rush of calming the nerves
Dormancy agent includes vegetable-derived components and synthesis derived components, 3g vegetable-derived components, 0.3g synthesis derived components cyclamen aldehydes and 15g forming agents
Tablet is pressed into using tablet press machine after mixing, then the particle of the mesh of granularity 60 is made through pulverizer.
Vegetable-derived components are by mass ratio 2:2:1:1:0.5 Chinese ilex essential oil, cus-cus essential oil, styrax essential oil, gardenia
Essential oil, honeysuckle essential oil mix.
The preparation of forming agent：
(1) deionized water is added dropwise until being completely dissolved into 15g Sensor Chip CM 5 sodium under stirring, recycles dust technology to adjust
PH value is saved to 3-4, and is heated to 60-70 DEG C of insulated and stirred, a pH value is detected every 5min, is added when pH value is more than 4 dilute
Nitric acid so that pH value control in 3-4, when system pH in 15min continually and steadily in 3-4 when add 2g N- methylol acryloyls
Amine, continue to be heated to reflux state insulated and stirred 3h, add 3g trimethylol-propane trimethacrylates and 0.05g over cures
Sour potassium, flowed back insulated and stirred 2h again, and gained mixture is sent into spray dryer when naturally cooling to less than 50 DEG C, dries institute
Obtain particle and micro mist is made through micronizer, produce water-based glucan-acrylic resin compound；
(2) heated after mixing 3g cation guar gums, 0.5g food-grades gamma-polyglutamic acid and 0.01g butyl titanates
To molten condition insulated and stirred 1h, to weight boiling water such as gained solid additions when naturally cooling to less than 70 DEG C, and it is heated to back
Stream mode insulated and stirred 15min, gained mixture is concentrated to reach 60-70% to solid content, is finally sent into freeze drier,
Dry gained solid and micro mist is made through micronizer, produce modified guar；
(3) 8g hydrophobicity aerosils are added into above-mentioned made water-based glucan-acrylic resin compound, are changed
Property guar gum, 2g nano titanium oxides and 1g rilanit specials, are sufficiently mixed, produce forming agent.
Embodiment 6
It is a kind of have to calm the nerves promote the sachet content of dormancy effect, promoted dormancy agent and forming agent by calming the nerves and be made, the rush of calming the nerves
Dormancy agent includes vegetable-derived components and synthesis derived components, 3g vegetable-derived components, 0.3g synthesis derived components cyclamen aldehydes and 15g forming agents
Tablet is pressed into using tablet press machine after mixing, then the particle of the mesh of granularity 60 is made through pulverizer.
Vegetable-derived components are by mass ratio 2:2:1:1:0.5 Chinese ilex essential oil, cus-cus essential oil, styrax essential oil, gardenia
Essential oil, honeysuckle essential oil mix.
The preparation of forming agent：
(1) deionized water is added dropwise until being completely dissolved into 10g Sensor Chip CM 5 sodium under stirring, recycles dust technology to adjust
PH value is saved to 3-4, and is heated to 60-70 DEG C of insulated and stirred, a pH value is detected every 5min, is added when pH value is more than 4 dilute
Nitric acid so that pH value control in 3-4, when system pH in 15min continually and steadily in 3-4 when add 1g N- methylol acryloyls
Amine, continue to be heated to reflux state insulated and stirred 2h, add 2g trimethylol-propane trimethacrylates and 0.05g over cures
Sour potassium, flowed back insulated and stirred 1h again, and gained mixture is sent into spray dryer when naturally cooling to less than 50 DEG C, dries institute
Obtain particle and micro mist is made through micronizer, produce water-based glucan-acrylic resin compound；
(2) it is heated to after mixing 5g cation guar gums, 1g food-grades gamma-polyglutamic acid and 0.01g butyl titanates
Molten condition insulated and stirred 1h, to weight boiling water such as gained solid additions when naturally cooling to less than 70 DEG C, and it is heated to flowing back
State insulated and stirred 15min, gained mixture is concentrated to reach 60-70% to solid content, is finally sent into freeze drier, does
Micro mist is made through micronizer in dry gained solid, produces modified guar；
(3) 5g hydrophobicity aerosils are added into above-mentioned made water-based glucan-acrylic resin compound, are changed
Property guar gum, 3g nano titanium oxides and 1g rilanit specials, are sufficiently mixed, produce forming agent.
The modification of rilanit special：10g rilanit specials are first heated to molten condition insulated and stirred 5min, add 2g
Trihydroxymethylpropanyltri diglycidyl ether and 1g stearic acid, continue to be heated to 110-120 DEG C of insulated and stirred 2h, gained mixture with
5 DEG C/min cooling rate is cooled to 0-5 DEG C of insulation and stands 2h, produces modified hydrogenated castor oil.
Embodiment 7
It is a kind of have to calm the nerves promote the sachet content of dormancy effect, promoted dormancy agent and forming agent by calming the nerves and be made, the rush of calming the nerves
Dormancy agent includes vegetable-derived components and synthesis derived components, 3g vegetable-derived components, 0.3g synthesis derived components cyclamen aldehydes and 15g forming agents
Tablet is pressed into using tablet press machine after mixing, then the particle of the mesh of granularity 60 is made through pulverizer.
Vegetable-derived components are by mass ratio 2:2:1:1:0.5 Chinese ilex essential oil, cus-cus essential oil, styrax essential oil, gardenia
Essential oil, honeysuckle essential oil mix.
The preparation of forming agent：
(1) deionized water is added dropwise until being completely dissolved into 15g Sensor Chip CM 5 sodium under stirring, recycles dust technology to adjust
PH value is saved to 3-4, and is heated to 60-70 DEG C of insulated and stirred, a pH value is detected every 5min, is added when pH value is more than 4 dilute
Nitric acid so that pH value control in 3-4, when system pH in 15min continually and steadily in 3-4 when add 2g N- methylol acryloyls
Amine, continue to be heated to reflux state insulated and stirred 3h, add 3g trimethylol-propane trimethacrylates and 0.05g over cures
Sour potassium, flowed back insulated and stirred 2h again, and gained mixture is sent into spray dryer when naturally cooling to less than 50 DEG C, dries institute
Obtain particle and micro mist is made through micronizer, produce water-based glucan-acrylic resin compound；
(2) heated after mixing 3g cation guar gums, 0.5g food-grades gamma-polyglutamic acid and 0.01g butyl titanates
To molten condition insulated and stirred 1h, to weight boiling water such as gained solid additions when naturally cooling to less than 70 DEG C, and it is heated to back
Stream mode insulated and stirred 15min, gained mixture is concentrated to reach 60-70% to solid content, is finally sent into freeze drier,
Dry gained solid and micro mist is made through micronizer, produce modified guar；
(3) 8g hydrophobicity aerosils are added into above-mentioned made water-based glucan-acrylic resin compound, are changed
Property guar gum, 2g nano titanium oxides and 1g rilanit specials, are sufficiently mixed, produce forming agent.
The modification of rilanit special：5g rilanit specials are first heated to molten condition insulated and stirred 3min, add 1g
Trihydroxymethylpropanyltri diglycidyl ether and 0.5g stearic acid, continue to be heated to 110-120 DEG C of insulated and stirred 1h, gained mixture
0-5 DEG C of insulation is cooled to 5 DEG C/min cooling rate and stands 2h, produces modified hydrogenated castor oil.
Reference examples 1
It is a kind of have to calm the nerves promote the sachet content of dormancy effect, promoted dormancy agent and forming agent by calming the nerves and be made, the rush of calming the nerves
Dormancy agent includes vegetable-derived components and synthesis derived components, 3g vegetable-derived components, 0.3g synthesis derived components cyclamen aldehydes and 15g forming agents
Tablet is pressed into using tablet press machine after mixing, then the particle of the mesh of granularity 60 is made through pulverizer.
Vegetable-derived components are by mass ratio 2:2:1:1:0.5 Chinese ilex essential oil, cus-cus essential oil, styrax essential oil, gardenia
Essential oil, honeysuckle essential oil mix.
The preparation of forming agent：
(1) deionized water is added dropwise until being completely dissolved into 15g Sensor Chip CM 5 sodium under stirring, recycles dust technology to adjust
PH value is saved to 3-4, and is heated to 60-70 DEG C of insulated and stirred, a pH value is detected every 5min, is added when pH value is more than 4 dilute
Nitric acid so that pH value control in 3-4, when system pH in 15min continually and steadily in 3-4 when add 2g N- methylol acryloyls
Amine, continue to be heated to reflux state insulated and stirred 3h, add 3g trimethylol-propane trimethacrylates and 0.05g over cures
Sour potassium, flowed back insulated and stirred 2h again, and gained mixture is sent into spray dryer when naturally cooling to less than 50 DEG C, dries institute
Obtain particle and micro mist is made through micronizer, produce water-based glucan-acrylic resin compound；
(2) 8g hydrophobicity aerosils, 3g are added into above-mentioned made water-based glucan-acrylic resin compound
Cation guar gum, 2g nano titanium oxides and 1g rilanit specials, are sufficiently mixed, produce forming agent.
Reference examples 2
It is a kind of have to calm the nerves promote the sachet content of dormancy effect, promoted dormancy agent and forming agent by calming the nerves and be made, the rush of calming the nerves
Dormancy agent includes vegetable-derived components and synthesis derived components, 3g vegetable-derived components, 0.3g synthesis derived components cyclamen aldehydes and 15g forming agents
Tablet is pressed into using tablet press machine after mixing, then the particle of the mesh of granularity 60 is made through pulverizer.
Vegetable-derived components are by mass ratio 2:2:1:1:0.5 Chinese ilex essential oil, cus-cus essential oil, styrax essential oil, gardenia
Essential oil, honeysuckle essential oil mix.
The preparation of forming agent：
(1) heated after mixing 3g cation guar gums, 0.5g food-grades gamma-polyglutamic acid and 0.01g butyl titanates
To molten condition insulated and stirred 1h, to weight boiling water such as gained solid additions when naturally cooling to less than 70 DEG C, and it is heated to back
Stream mode insulated and stirred 15min, gained mixture is concentrated to reach 60-70% to solid content, is finally sent into freeze drier,
Dry gained solid and micro mist is made through micronizer, produce modified guar；
(2) 8g hydrophobicity aerosils, modified guar, 2g nanometers two are added into 15g Sensor Chip CM 5 sodium
Titanium oxide and 1g rilanit specials, are sufficiently mixed, produce forming agent.
Embodiment 8
The made sachet content of embodiment 1-7, reference examples 1-2 is sewn into the sachet of same size (using identical respectively
The utricule fabric of material), and determine the performance of sachet.
Select area 15m2, height 2.2-2.5m test cabinet, a certain position of test cabinet be provided with diameter 10cm air-vent,
Made sachet is placed on the ground of test cabinet, and the flavor concentration in test cabinet inner air is determined according to setting time, is surveyed
It is as shown in table 1 to determine concentration data.
The performance after sachet is made in the sachet content of the present invention of table 1
The general principle and principal character and advantages of the present invention of the present invention has been shown and described above.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the simply explanation described in above-described embodiment and specification is originally
The principle of invention, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, these changes
Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its
Equivalent thereof.
Claims (6)
- A kind of 1. sachet content with rush dormancy effect of calming the nerves, it is characterised in that：Promoted dormancy agent and forming agent by calming the nerves and be made, institute State to calm the nerves and promote dormancy agent comprising vegetable-derived components and synthesize derived components, vegetable-derived components, synthesis derived components and forming agent mix in proportion Tablet is pressed into using tablet press machine after conjunction, then the particle of granularity 40-80 mesh is made through pulverizer.
- 2. the sachet content with rush dormancy effect of calming the nerves according to claim 1, it is characterised in that：The plant source into It is 1-5 to divide, synthesize derived components and the mass ratio of forming agent:0.1-0.5:5-15.
- 3. the sachet content with rush dormancy effect of calming the nerves according to claim 1, it is characterised in that：The plant source into Divide by mass ratio 2:2:1:1:0.5 Chinese ilex essential oil, cus-cus essential oil, styrax essential oil, cape jasmine flower essential oil, honeysuckle essential oil are mixed Conjunction forms.
- 4. the sachet content with rush dormancy effect of calming the nerves according to claim 3, it is characterised in that：The Chinese ilex essence Oil, cus-cus essential oil, styrax essential oil, cape jasmine flower essential oil, honeysuckle essential oil are by leaf of Chinese ilex, cus-cus, styrax, cape jasmine Flower, honeysuckle are made through steam distillation.
- 5. the sachet content with rush dormancy effect of calming the nerves according to claim 1, it is characterised in that：The synthetic source into The one or more being selected from cyclamen aldehyde, bergamot aldehyde, piperonal, myristic aldehyde.
- 6. the sachet content with rush dormancy effect of calming the nerves according to claim 1, it is characterised in that：The forming agent choosing One or more in crospovidone, sodium carboxymethylcellulose, microcrystalline cellulose, HPMC.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109820966A (en) * | 2019-04-03 | 2019-05-31 | 福建卫生职业技术学院 | A kind of preparation method and application of novel sachet |
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