CN107661438A - A kind of sophora bud oral liquid for treating diabetes and preparation method thereof - Google Patents
A kind of sophora bud oral liquid for treating diabetes and preparation method thereof Download PDFInfo
- Publication number
- CN107661438A CN107661438A CN201711198149.5A CN201711198149A CN107661438A CN 107661438 A CN107661438 A CN 107661438A CN 201711198149 A CN201711198149 A CN 201711198149A CN 107661438 A CN107661438 A CN 107661438A
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- China
- Prior art keywords
- parts
- oral liquid
- sophora bud
- diabetes
- treatment
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- Pending
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Abstract
The invention provides a kind of sophora bud oral liquid for treating diabetes, in terms of parts by weight, including following composition：100 parts of stir-baked FLOS SOPHORAE IMMATURUS, 20 50 parts of ginkgo leaf, 15 30 parts of Chinese Fevervine Herb, 10 20 parts of PUDIJIN, 5 15 parts of flaccid knotweed herb, 5 20 parts of kwan-yin tea, 5 15 parts of Agrimony, 10 20 parts of Momordica grosvenori.The oral liquid energy of the sophora bud of the treatment diabetes is adjusted along internal system function, activation and repairing pancreas cell, it is recovered the function of excreting insulin, is increased internal insulin level and balance blood sugar, can fundamentally be treated diabetes.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of sophora bud oral liquid for treating diabetes and its preparation side
Method.
Background technology
There are nearly 20 kinds of Chinese scholartrees such as a Chinese scholartree, needle Chinese scholartree, Huang Huai, beans Chinese scholartree, golden Chinese scholartree in China, using golden Chinese scholartree to be best, because of color
Gained the name in golden yellow, its plant of yield maximum, rutin content highest, the grain of rice is big and real, so being acknowledged as the top grade in the sophora bud.
Golden Chinese scholartree complete stool can be used as medicine, and the sophora bud receives sword hemostatic, and hypotensive to be cooling；Fruit heat-clearing, moisten liver, cool blood, stop
Blood.The sophora bud is the drying flower or bud of Chinese scholartree, and summer flower is plucked open, stored up after drying, be available for annual use.The sophora bud has
Cooling blood and hemostasis, the function of clearing liver-fire；The treatment of the diseases such as clinic is used for having blood in stool, hemorrhoid blood, bloody flux, uterine bleeding, haematemesis.
Due to effect of the sophora bud to capillary, the normal resistance of capillary can be kept, reduces vasopermeability, can
Make blood vessel because fragility increase and the capillary of bleeding recover normal elasticity, therefore have softening blood vessel, increase blood vessel elasticity, to artery
Hardening has emollescence, has preventive and therapeutic effect to diabetes, the retinitis；Its preparation, which has, promotes microcirculation, blood fat-reducing blood pressure-decreasing, efficiency drop
Low liver, sustainer and blood middle cholesterol content have functions of lowering blood-fat and reducing weight to overweight people；Due to above-mentioned effect, all knowing at all times,
Li Shizhen (1518-1593 A.D.)《The careless detailed outline of wood》The healthcare function of ancestors' sophora bud is described already.
Therefore, it is necessary to a kind of sophora bud oral liquid of healthy treatment diabetes is developed, to control and solve diabetes group
The problem of body blood glucose rise, and can effectively prevent the symptom complex of diabetes.
The content of the invention
An object of the present invention is to provide a kind of sophora bud oral liquid for treating diabetes, the active component in recuperating tea
Fully indissoluble, the polysaccharide active components in raw material are fully played, these plant polyose energy effective supply glycosurias
Disease lacks sugared mechanism, adjusts along internal system function, activation and repairing pancreas cell, it is recovered the function of excreting insulin, increases
Add internal insulin level and balance blood sugar.
The second object of the present invention is the preparation method for the sophora bud oral liquid for providing the treatment diabetes.
The sophora bud oral liquid of present invention treatment diabetes, in terms of parts by weight, raw material includes following composition：
100 parts of stir-baked FLOS SOPHORAE IMMATURUS, ginkgo leaf 20-50 parts, Chinese Fevervine Herb 15-30 parts, PUDIJIN 10-20 parts, flaccid knotweed herb 5-15 parts, kwan-yin tea
5-20 parts, Agrimony 5-15 parts, Momordica grosvenori 10-20 parts.
The preferred 35-50 parts of wherein described ginkgo leaf.
The preferred 20-25 parts of wherein described Chinese Fevervine Herb.
The preferred 10-15 parts of wherein described PUDIJIN.
The preferred 5-10 parts of wherein described flaccid knotweed herb.
The preferred 7-15 parts of wherein described kwan-yin tea.
The preferred 10-15 parts of wherein described Agrimony.
The sophora bud oral liquid raw material of present invention treatment diabetes can also add acanthopanax 10-20 parts.
The sophora bud oral liquid raw material of present invention treatment diabetes can also add stem of noble dendrobium leaf 5-9 parts.
The preparation method of the sophora bud oral liquid of present invention treatment diabetes, in turn includes the following steps：
（1）The raw material weighed up is put into decocting container, adds water, boiled rear slow fire is decocted 20-40 minutes, and maintenance boiling water is
Can；Wherein the weight ratio of Chinese medicine material and water is 1:（3-5）；
（2）By well-done medical filtration；It is filling.
The sophora bud oral liquid instructions of taking of present invention treatment diabetes is as follows：Warmly take 3 times a day, each 50-200ml.
The sophora bud oral liquid of present invention treatment diabetes is using a variety of natural plants as raw material, is exactly the characteristics of prescription maximum
Using the efficient combination of Nantural non-toxic plant, form the compounding mechanism of the monarch of Chinese traditional medicine principle, make the activity of each raw material into
Point fully it is indissoluble, be made treatment diabetes sophora bud oral liquid.
Diabetes are caused by the endocrine system disorder of people, are the symptoms showed before serious disease arrives, this disease is simultaneously
Non- disease, disease are the tendencys of disease, and disease is the outburst of the comprehensive accumulation of disease, and disease can be eliminated by nursing one's health physical function completely,
The root of disease nips in the bud；The sophora bud oral liquid of present invention treatment diabetes improves the anti-of body around this principle
Sick ability, the effect that human body autologous stem cells self-replacation is played along internal system function is adjusted, activation and repairing pancreas are thin
Born of the same parents, by the factor caused by stem cell, stimulate beta Cell of islet to regenerate, it is recovered the function of excreting insulin, increase is internal
Insulin level and balance blood sugar.
The sophora bud oral liquid of present invention treatment diabetes is adapted to that immune power is low, resistance against diseases is poor, weak and sickly, high
Blood pressure, high fat of blood, obesity, type 1 diabetes and diabetes B patient, can fundamentally treat diabetes.
The present invention is raw materials used to be described as follows：
The sophora bud：Sophora bud broad sense is for legume Chinese scholartree（Sophora japonica L.）Dry flower and flower；Sophora bud main product in
The ground such as Henan, Shandong, Shanxi, Shaanxi, Anhui, Hebei, Jiangsu, Guizhou, in recent years the ground such as Ningxia, Gansu also have scale, more
Also there is the plantation of large area in south；Summer flower harvests its bud when not open, is referred to as " sophora bud "；The flowers are in blossom harvests when putting, and is referred to as " Chinese scholartree
Flower "；Branch, stalk and the impurity of inflorescence are removed after harvesting, is dried in time, life is used, fries and use or fry charcoal use；The sophora bud of the present invention is golden Chinese scholartree
The sophora bud.
Ginkgo leaf：Ginkgoaceae plant Ginkgo biloba Ginkgo biloba L. dried leaf；Autumn leaf harvests when still green, dry in time
It is dry；Generally artificial cultivation；Cultivation area north to Liaoning, Nan Da Guangdong, from the east of Zhejiang, west reaches Shaanxi, Gansu, southwest to four
The ground such as river, Guizhou, Yunnan；With promoting blood circulation and removing blood stasis, remove obstruction in channels to relieve pain, astringe the lung and relieving asthma, the effect of changing turbid lipid-loweringing；For obstruction of collaterals by blood stasis,
Chest impediment and cardialgia, hemiplegia, deficiency syndrome of the lung cough and asthma, hyperlipidemia.
Chinese Fevervine Herb：For the herb of madder wort fevervine, summer harvesting herb, dry；Its sweet, slight bitter, it is mild-natured；With dispelling
Wind dampness removing, analgesic antidotal, promoting digestion and removing indigestion, the effect of activating blood circulation and reducing swelling；For rheumatalgia, traumatic injury, traumatic pain, liver
Courage and stomach and intestine angina, indigestion, infantile malnutrition, bronchitis；It is used for dermatitis, eczema and sore swollen toxin outside.
PUDIJIN：PUDIJIN ground M.-dodecandrum, medicinal plant, is used as medicine with herb or root.
Flaccid knotweed herb：Scientific name Polygonatum odoratum（Mill.）Druce, it is Liliaceae herbaceos perennial；
Rhizome it is horizontal walk, meat yellow-white, dense most fibrous roots；Blade face green, below grey.Flaccid knotweed herb tool yin-nourishing, moisturize, heat-clearing, life
Tianjin, cough-relieving and other effects.As tonic, the diseases such as consumption of YIN caused by febrile disease, abnormal heat cough caused by dryness, heart disease, diabetes, tuberculosis are cured mainly, and
High-grade nourishing food, delicacies and beverage can be made, it is with health role.
Kwan-yin tea：White hair Yin Lumei, shrub, high 0.3-2m；Peel off the raw longitudinal direction of tree；Sprig taupe or puce, it is dilute
Dredge pubescence.Leaf alternate, imparipinnate leaf generally have that leaflet 2 is right, and even is 3 leaflets, above 1 pair of small leaf base is downward and axis congruence
Close；Petiole is by thin pubescence；Stipule film quality, hair or several hairless；Vanelets are oval, ellipse or ovate-elliptic long, long
0.5-1.2cm, wide 0.4-0.8cm, tip circle is blunt or anxious point, and base portion is wedge-shaped or nearly circle is died, full edge, two sides green, above or it is more
Or few raw pubescence of volt, below it is close by white fluff or thin,tough silk hair；For hot summer weather dizziness；Disorder of stomach-energy；Retention of food and drink；Irregular menstruation；
With lower more than.
Agrimony：It is the rose family, Agrimony category herbaceos perennial；This kind of young stem and leaf is edible, not only nutritious, and
And the good merchantable brand with very strong anticancer function, actually game；Agrimony herb, root and hibernaculum are used as medicine.Nature and flavor：It is bitter, dry；Enter
Lung, liver, the spleen channel；There are astringing to arrest bleeding, anti-inflammatory, stop dysentery, removing toxic substances, desinsection, the function of invigorating vital energy and reinforce the heart；Cure mainly haematemesis, spitting of blood, bleeding from five sense organs or subcutaneous tissue,
Hematuria, functional uterine bleeding, dysentery, gastroenteritis, Trichomonas vaginalis, internal lesion caused by overexertion are powerless, sprain lumbago, and external application controls carbuncle and treats sore.
Acanthopanax：Classification system Acanthopanax senticosus (Rupr. Maxim.) Harms, alias：Bank
Bent stick, tiger are hasty and careless, 100 pins, have the function that bowl spares strengthening the essence, hard muscles and bones, Qiang Zhiyi.
The stem of noble dendrobium：Also known as celestial dry measure used in former times orchid rhythm, not dead grass, whorlleaf stonecrop herb, purple entangle celestial strain, bracketplant, Lin Lan, prohibition of life, nobile flower etc..Stem is straight
Vertical, meat shape is plump, and slightly flat cylinder is long 10-60 centimetres, slightly up to 1.3 centimetres；Medicinal plant, property slightly sweet flavor is micro- salty, trembles with fear,
Return stomach, kidney, lung channel.Reinforcing stomach reg fluid, nourishing Yin and clearing heat.For impairment of yin body fluid deficiency, dry polydipsia, deficiency of food is retched, after being ill abnormal heat, and mesh is secretly not
It is bright.
Momordica grosvenori：The fruit of the perennial liana of Curcurbitaceae, its primary efficacy is can be relieving cough and reducing sputum；Fruits nutrition is worth
It is very high, containing abundant vitamin C（Contain 400 milligrams~500 milligrams in every 100 grams of fresh fruits）And glucoside, fructose, glucose, egg
White matter, lipid etc..
Embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and should not be taken as limiting the scope of the invention.
Embodiment 1
Stir-baked FLOS SOPHORAE IMMATURUS 100kg, ginkgo leaf 40kg, Chinese Fevervine Herb 20kg, PUDIJIN 10kg, flaccid knotweed herb 10kg, kwan-yin tea 10kg, Agrimony
10 kg, the kg of Momordica grosvenori 12.
Embodiment 2
Stir-baked FLOS SOPHORAE IMMATURUS 100kg, ginkgo leaf 35kg, Chinese Fevervine Herb 25kg, PUDIJIN 10kg, flaccid knotweed herb 10kg, kwan-yin tea 10kg, Agrimony
10 kg, the kg of Momordica grosvenori 12.
Embodiment 3
Stir-baked FLOS SOPHORAE IMMATURUS 100kg, ginkgo leaf 45kg, Chinese Fevervine Herb 15kg, PUDIJIN 11kg, flaccid knotweed herb 11kg, kwan-yin tea 11kg, Agrimony
9 kg, the kg of Momordica grosvenori 15.
Embodiment 4
Stir-baked FLOS SOPHORAE IMMATURUS 100kg, ginkgo leaf 38kg, Chinese Fevervine Herb 22kg, PUDIJIN 11kg, flaccid knotweed herb 11kg, kwan-yin tea 9kg, Agrimony
11 kg, the kg of Momordica grosvenori 15.
Embodiment 5
Stir-baked FLOS SOPHORAE IMMATURUS 100kg, ginkgo leaf 42kg, Chinese Fevervine Herb 18kg, PUDIJIN 12kg, flaccid knotweed herb 13kg, kwan-yin tea 7kg, Agrimony
13 kg, the kg of Momordica grosvenori 16.
Embodiment 6
Stir-baked FLOS SOPHORAE IMMATURUS 100kg, ginkgo leaf 43kg, Chinese Fevervine Herb 17kg, PUDIJIN 12kg, flaccid knotweed herb 11kg, kwan-yin tea 13kg, Agrimony
14 kg, the kg of Momordica grosvenori 14.
Embodiment 7
Stir-baked FLOS SOPHORAE IMMATURUS 100kg, ginkgo leaf 37kg, Chinese Fevervine Herb 27kg, PUDIJIN 14kg, flaccid knotweed herb 13kg, kwan-yin tea 17kg, Agrimony
15 kg, Momordica grosvenori 12kg.
Embodiment 8
Stir-baked FLOS SOPHORAE IMMATURUS 100kg, ginkgo leaf 40kg, Chinese Fevervine Herb 20kg, PUDIJIN 13kg, flaccid knotweed herb 15kg, kwan-yin tea 15kg, Agrimony
9 kg, Momordica grosvenori 13kg.
Embodiment 9
Stir-baked FLOS SOPHORAE IMMATURUS 100kg, ginkgo leaf 40kg, Chinese Fevervine Herb 20kg, PUDIJIN 15kg, flaccid knotweed herb 10kg, kwan-yin tea 10kg, Agrimony
10 kg, acanthopanax 15kg, Momordica grosvenori 13kg.
Embodiment 10
Stir-baked FLOS SOPHORAE IMMATURUS 100kg, ginkgo leaf 40kg, Chinese Fevervine Herb 20kg, PUDIJIN 15kg, flaccid knotweed herb 10kg, kwan-yin tea 10kg, Agrimony
10 kg, stem of noble dendrobium leaf 5 kg, Momordica grosvenori 13kg.
Embodiment 11
Stir-baked FLOS SOPHORAE IMMATURUS 100kg, ginkgo leaf 40kg, Chinese Fevervine Herb 20kg, PUDIJIN 15kg, flaccid knotweed herb 10kg, kwan-yin tea 10kg, Agrimony
15 kg, the kg of acanthopanax 15, stem of noble dendrobium leaf 5 kg, Momordica grosvenori 15kg.
Embodiment 12
Stir-baked FLOS SOPHORAE IMMATURUS 100kg, ginkgo leaf 40kg, Chinese Fevervine Herb 20kg, PUDIJIN 15kg, flaccid knotweed herb 10kg, kwan-yin tea 10kg, Agrimony
15 kg, acanthopanax 14kg, stem of noble dendrobium leaf 7 kg, Momordica grosvenori 15kg.
Comparative example 1
Stir-baked FLOS SOPHORAE IMMATURUS 100kg, ginkgo leaf 10kg, Chinese Fevervine Herb 20kg, PUDIJIN 10kg, flaccid knotweed herb 10kg, kwan-yin tea 10kg, Agrimony
15 kg, the kg of acanthopanax 15, stem of noble dendrobium leaf 5 kg, Momordica grosvenori 15kg.
Comparative example 1 reduces the dosage of ginkgo leaf on the basis of embodiment 11, and preparation method is the same as embodiment 11.
Comparative example 2
Comparative example 2 eliminates ginkgo leaf on the basis of embodiment 11, and preparation method is the same as embodiment 11.
Embodiment, comparative example preparation method are as follows：
（1）The raw material weighed up is put into decocting container, adds water, boiled rear slow fire is decocted 30 minutes, maintains boiling water；Its
The weight ratio of middle Chinese medicine material and water is 1:4；
（2）By well-done medical filtration；It is filling.
The sophora bud oral liquid of present invention treatment diabetes is found that it has blood sugar reducing function, and does not have for animal experiment
There is side effect, then be used for clinical test.
The using effect of above example and comparative example is as follows.
(1) hyperglycemia patient using effect:
Fasting blood-glucose is more than 6, and postprandial blood sugar is more than or equal to 7.7 can say it is hyperglycaemia, will be not reaching to diabetes standard
The people of hyperglycemia patient 140, is equally divided into 14 groups, every group of 10 people, takes embodiment 1-12 and comparative example 1-2 treatment glycosuria respectively
The sophora bud oral liquid of disease, the sophora bud oral liquid instructions of taking of present invention treatment diabetes are as follows：Warmly take 3 times a day, each 50ml,
Diet does not limit, and is usual diet, and after half a year, embodiment 1-12 Fasting Glucose and postprandial blood sugar full recovery are just
Often, comparative example 1 has 5 to recover normal, and comparative example 2 has 4 to recover normal.
(2) type 1 diabetes people using effect:
From the ineffective diabetic of 140 conventional medicine controls sugar of hospitalization, above patient is equally divided into 14 groups,
Every group of 10 people, treating insulin injection 3 times a day before could control blood glucose normal, take embodiment 1-12 and right respectively later
The sophora bud oral liquid of ratio 1-2 treatment diabetes, warmly takes 3 times a day, and each 50ml, diet is diabetic diet, 2 times a day
Insulin injection, after 45 days, it is discontinued 1 week, determines fasting blood-glucose, 2h-plasma glucose respectively, the results are shown in Table 1.
1 14 groups of patients of table drink front and rear clinic and laboratory data
。
As it can be seen from table 1 after embodiment 11-12 patient drinks 2 months, effect is best, fasting blood-glucose substantially close to
Normally, postprandial 2 hours blood glucose is also higher.
Embodiment 11-12 patient continues after drinking two weeks, and insulin is injecting 1 can control blood glucose just daily
Often, be further continued for after drinking 5 months, insulin stops injection, continues to drink the sophora bud oral liquid for the treatment of diabetes, fasting blood-glucose and
Postprandial blood sugar is normal.
2 times a day, postprandial blood sugar is higher for injection of insulin after embodiment 1-10 patient drinks 2 months, continues to drink 1
After month, injection of insulin 1 time a day, can control blood glucose normal, continue after drinking 8 months, and insulin stops injection, and blood glucose is normal
The symptom such as every group of 3-5 example of patient, other patient main suit's giddy, tinnitus, uncomfortable in chest, shortness of breath, insomnias disappear, but insulin stop
Injection, blood glucose or higher, then 1 insulin of injection daily, while quote Chinese medicine composition of the present invention and can control blood glucose just
Often.
After the patient of comparative example 1 drinks 2 months, 2 blood glucose of injection of insulin can not control normally, it is also necessary to inject 3 times
, continue after taking 9 months, 2 blood glucose of injection of insulin can control normally.
After the patient of comparative example 2 drinks 2 months, 2 blood glucose of injection of insulin can not control normally, it is also necessary to inject 3 times
, continue after taking 12 months, 2 blood glucose of injection of insulin could control normally.
Claims (10)
1. a kind of sophora bud oral liquid for treating diabetes, it is characterised in that in terms of parts by weight, raw material includes following composition：Fry Chinese scholartree
Rice 100 parts, ginkgo leaf 20-50 parts, Chinese Fevervine Herb 15-30 parts, PUDIJIN 10-20 parts, flaccid knotweed herb 5-15 parts, kwan-yin tea 5-20 parts,
Agrimony 5-15 parts, Momordica grosvenori 10-20 parts.
2. the sophora bud oral liquid for the treatment of diabetes according to claim 1, it is characterised in that described ginkgo leaf is 35-50
Part.
3. the sophora bud oral liquid for the treatment of diabetes according to claim 1, it is characterised in that described Chinese Fevervine Herb is 20-25
Part.
4. the sophora bud oral liquid for the treatment of diabetes according to claim 1, it is characterised in that described PUDIJIN is 10-15
Part.
5. the sophora bud oral liquid for the treatment of diabetes according to claim 1, it is characterised in that described flaccid knotweed herb is 5-10
Part.
6. the sophora bud oral liquid for the treatment of diabetes according to claim 1, it is characterised in that described kwan-yin tea is 7-15
Part.
7. the sophora bud oral liquid for the treatment of diabetes according to claim 1, it is characterised in that described Agrimony is 10-15
Part.
8. the sophora bud oral liquid for the treatment of diabetes according to claim 1, it is characterised in that also including acanthopanax 10-
20 parts.
9. the sophora bud oral liquid for the treatment of diabetes according to claim 1, it is characterised in that also including stem of noble dendrobium leaf 5-9 parts.
10. the preparation method of the sophora bud oral liquid of diabetes is treated according to claim 1, it is characterised in that include successively such as
Lower step：
（1）The raw material weighed up is put into decocting container, adds water, boiled rear slow fire is decocted 20-40 minutes, and maintenance boiling water is
Can；Wherein the weight ratio of Chinese medicine material and water is 1:（3-5）；
（2）By well-done medical filtration；It is filling.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103283890A (en) * | 2013-06-19 | 2013-09-11 | 山东华夏茶联茶业有限公司 | Health-care dark tea |
| CN105412668A (en) * | 2015-12-21 | 2016-03-23 | 暨南大学 | Traditional Chinese medicine composition for treating diabetes and preparation method of traditional Chinese medicine composition |
-
2017
- 2017-11-25 CN CN201711198149.5A patent/CN107661438A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103283890A (en) * | 2013-06-19 | 2013-09-11 | 山东华夏茶联茶业有限公司 | Health-care dark tea |
| CN105412668A (en) * | 2015-12-21 | 2016-03-23 | 暨南大学 | Traditional Chinese medicine composition for treating diabetes and preparation method of traditional Chinese medicine composition |
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