CN107737241A - Treat sophora bud Chinese medicine composition of diabetes and preparation method thereof - Google Patents

Abstract

The invention provides a kind of sophora bud Chinese medicine composition for treating diabetes, in terms of parts by weight, including following composition：100 parts of stir-baked FLOS SOPHORAE IMMATURUS, 20 50 parts of Qingqian Willow leaf, 15 30 parts of Chinese Fevervine Herb, 5 15 parts of ginkgo leaf, 5 15 parts of radix polygonati officinalis, 5 20 parts of kwan-yin tea, 5 15 parts of Agrimony, 10 20 parts of Momordica grosvenori.The sophora bud Chinese medicine composition of the treatment diabetes can be adjusted along internal system function, activation and repairing pancreas cell, it is recovered the function of excreting insulin, increase internal insulin level and balance blood sugar, can fundamentally treat diabetes.

Description

Treat sophora bud Chinese medicine composition of diabetes and preparation method thereof

Technical field

The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of sophora bud Chinese medicine composition for treating diabetes and its preparation Method.

Background technology

There are nearly 20 kinds of Chinese scholartrees such as a Chinese scholartree, needle Chinese scholartree, Huang Huai, beans Chinese scholartree, golden Chinese scholartree in China, using golden Chinese scholartree to be best, because of color Gained the name in golden yellow, its plant of yield maximum, rutin content highest, the grain of rice is big and real, so being acknowledged as the top grade in the sophora bud.

Golden Chinese scholartree complete stool can be used as medicine, and the sophora bud receives sword hemostatic, and hypotensive to be cooling；Fruit heat-clearing, moisten liver, cool blood, stop Blood.The sophora bud is the drying flower or bud of Chinese scholartree, and summer flower is plucked open, stored up after drying, be available for annual use.The sophora bud has Cooling blood and hemostasis, the function of clearing liver-fire；The treatment of the diseases such as clinic is used for having blood in stool, hemorrhoid blood, bloody flux, uterine bleeding, haematemesis.

Due to effect of the sophora bud to capillary, the normal resistance of capillary can be kept, reduces vasopermeability, can Make blood vessel because fragility increase and the capillary of bleeding recover normal elasticity, therefore have softening blood vessel, increase blood vessel elasticity, to artery Hardening has emollescence, has preventive and therapeutic effect to diabetes, the retinitis；Its preparation, which has, promotes microcirculation, blood fat-reducing blood pressure-decreasing, efficiency drop Low liver, sustainer and blood middle cholesterol content have functions of lowering blood-fat and reducing weight to overweight people；Due to above-mentioned effect, all knowing at all times, Li Shizhen (1518-1593 A.D.)《The careless detailed outline of wood》The healthcare function of ancestors' sophora bud is described already.

Therefore, it is necessary to a kind of sophora bud Chinese medicine composition of healthy treatment diabetes is developed, to control and solve glycosuria The problem of sick colony's blood glucose rise, and can effectively prevent the symptom complex of diabetes.

The content of the invention

An object of the present invention is to provide a kind of sophora bud Chinese medicine composition for treating diabetes, the activity in recuperating tea Composition is fully indissoluble, and the polysaccharide active components in raw material are fully played, these plant polyose energy effective supply Diabetes lack sugared mechanism, adjust along internal system function, activation and repairing pancreas cell, it is recovered the work(of excreting insulin Can, increase internal insulin level and balance blood sugar.

The second object of the present invention is the preparation method for the sophora bud Chinese medicine composition for providing the treatment diabetes.

The sophora bud Chinese medicine composition of present invention treatment diabetes, in terms of parts by weight, raw material includes following composition：

100 parts of stir-baked FLOS SOPHORAE IMMATURUS, Qingqian Willow leaf 20-50 parts, Chinese Fevervine Herb 15-30 parts, ginkgo leaf 5-15 parts, radix polygonati officinalis 5-15 parts, kwan-yin tea 5-20 parts, Agrimony 5-15 parts, Momordica grosvenori 10-20 parts.

The preferred 35-50 parts of wherein described Qingqian Willow leaf.

The preferred 20-25 parts of wherein described Chinese Fevervine Herb.

The preferred 10-15 parts of wherein described ginkgo leaf.

The preferred 5-10 parts of wherein described radix polygonati officinalis.

The preferred 7-15 parts of wherein described kwan-yin tea.

The preferred 10-15 parts of wherein described Agrimony.

The sophora bud Chinese medicine composition raw material of present invention treatment diabetes can also add acanthopanax 10-20 parts.

The sophora bud Chinese medicine composition raw material of present invention treatment diabetes can also add stem of noble dendrobium leaf 5-9 parts.

The preparation method of the sophora bud Chinese medicine composition of present invention treatment diabetes, in turn includes the following steps：

（1）The raw material weighed up is put into decocting container, adds water, boiled rear slow fire is decocted 20-40 minutes, and maintenance boiling water is Can；Wherein the weight ratio of Chinese medicine material and water is 1:（3-5）；

（2）By well-done medical filtration；It is filling.

The sophora bud Chinese medicine composition instructions of taking of present invention treatment diabetes is as follows：Warmly take 3 times a day, each 50- 200ml。

The sophora bud Chinese medicine composition of present invention treatment diabetes is using a variety of natural plants as raw material, the characteristics of prescription maximum It is exactly the efficient combination using Nantural non-toxic plant, forms the compounding mechanism of the monarch of Chinese traditional medicine principle, make the work of each raw material Property composition it is fully indissoluble, be made treatment diabetes sophora bud Chinese medicine composition.

Diabetes are caused by the endocrine system disorder of people, are the symptoms showed before serious disease arrives, this disease is simultaneously Non- disease, disease are the tendencys of disease, and disease is the outburst of the comprehensive accumulation of disease, and disease can be eliminated by nursing one's health physical function completely, The root of disease nips in the bud；The sophora bud Chinese medicine composition of present invention treatment diabetes improves body around this principle Resistance against diseases, adjust the effect that human body autologous stem cells self-replacation is played along internal system function, activation and repairing pancreas Cell, by the factor caused by stem cell, stimulate beta Cell of islet to regenerate, it is recovered the function of excreting insulin, increase body Interior insulin level and balance blood sugar.

The sophora bud Chinese medicine composition of present invention treatment diabetes is adapted to that immune power is low, resistance against diseases is poor, weak more Disease, hypertension, high fat of blood, obesity, type 1 diabetes and diabetes B patient, can fundamentally treat diabetes.

The present invention is raw materials used to be described as follows：

The sophora bud：Sophora bud broad sense is for legume Chinese scholartree（Sophora japonica L.）Dry flower and flower；Sophora bud main product in The ground such as Henan, Shandong, Shanxi, Shaanxi, Anhui, Hebei, Jiangsu, Guizhou, in recent years the ground such as Ningxia, Gansu also have scale, more Also there is the plantation of large area in south；Summer flower harvests its bud when not open, is referred to as " sophora bud "；The flowers are in blossom harvests when putting, and is referred to as " Chinese scholartree Flower "；Branch, stalk and the impurity of inflorescence are removed after harvesting, is dried in time, life is used, fries and use or fry charcoal use；The sophora bud of the present invention is golden Chinese scholartree The sophora bud.

Qingqian Willow leaf：For juglandaceae plant blue or green money willow Cyclocarya paliurus（Batal.）Iljin. [Pterocarya paliurus Batal.;P. micropaliurus Tsoong] leaf, acrid flavour, slight bitter are mild-natured, mainly For skin tinea.

Chinese Fevervine Herb：For the herb of madder wort fevervine, summer harvesting herb, dry；Its sweet, slight bitter, it is mild-natured；Tool There is an expelling wind and removing dampness, analgesic antidotal, promoting digestion and removing indigestion, the effect of activating blood circulation and reducing swelling；For rheumatalgia, traumatic injury, traumatic pain Bitterly, liver and gall and stomach and intestine angina, indigestion, infantile malnutrition, bronchitis；It is used for dermatitis, eczema and sore swollen toxin outside.

Ginkgo leaf：Ginkgoaceae plant Ginkgo biloba Ginkgo biloba L. dried leaf；Autumn leaf harvests when still green, dry in time It is dry；Generally artificial cultivation；Cultivation area north to Liaoning, Nan Da Guangdong, from the east of Zhejiang, west reaches Shaanxi, Gansu, southwest to four The ground such as river, Guizhou, Yunnan；With promoting blood circulation and removing blood stasis, remove obstruction in channels to relieve pain, astringe the lung and relieving asthma, the effect of changing turbid lipid-loweringing；For obstruction of collaterals by blood stasis, Chest impediment and cardialgia, hemiplegia, deficiency syndrome of the lung cough and asthma, hyperlipidemia.

Radix polygonati officinalis：Scientific name Polygonatum odoratum（Mill.）Druce, it is Liliaceae herbaceos perennial.Root Stem it is horizontal walk, meat yellow-white, dense most fibrous roots.Blade face green, below grey；Radix polygonati officinalis tool yin-nourishing, moisturize, heat-clearing, promote the production of body fluid, only Cough and other effects.As tonic, the diseases such as consumption of YIN caused by febrile disease, abnormal heat cough caused by dryness, heart disease, diabetes, tuberculosis are cured mainly, and height can be made Level nourishing food, delicacies and beverage, it is with health role.

Kwan-yin tea：White hair Yin Lumei, shrub, high 0.3-2m；Peel off the raw longitudinal direction of tree；Sprig taupe or puce, it is dilute Dredge pubescence.Leaf alternate, imparipinnate leaf generally have that leaflet 2 is right, and even is 3 leaflets, above 1 pair of small leaf base is downward and axis congruence Close；Vanelets are oval, ellipse or ovate-elliptic, long 0.5-1.2cm, wide 0.4-0.8cm, tip circle are blunt or anxious long Point, base portion is wedge-shaped or nearly circle is died, full edge, two sides green, above the more or less raw pubescence of volt, below it is close by white fluff or thin,tough silk Hair；For hot summer weather dizziness；Disorder of stomach-energy；Retention of food and drink；Irregular menstruation；With lower more than.

Agrimony：It is the rose family, Agrimony category herbaceos perennial；This kind of young stem and leaf is edible, not only nutritious, and And the good merchantable brand with very strong anticancer function, actually game；Agrimony herb, root and hibernaculum are used as medicine.Nature and flavor：It is bitter, dry；Enter Lung, liver, the spleen channel；There are astringing to arrest bleeding, anti-inflammatory, stop dysentery, removing toxic substances, desinsection, the function of invigorating vital energy and reinforce the heart；Cure mainly haematemesis, spitting of blood, bleeding from five sense organs or subcutaneous tissue, Hematuria, functional uterine bleeding, dysentery, gastroenteritis, Trichomonas vaginalis, internal lesion caused by overexertion are powerless, sprain lumbago, and external application controls carbuncle and treats sore.

Acanthopanax：Classification system Acanthopanax senticosus (Rupr. Maxim.) Harms, alias：Bank Bent stick, tiger are hasty and careless, 100 pins, have the function that bowl spares strengthening the essence, hard muscles and bones, Qiang Zhiyi.

The stem of noble dendrobium：Also known as celestial dry measure used in former times orchid rhythm, not dead grass, whorlleaf stonecrop herb, purple entangle celestial strain, bracketplant, Lin Lan, prohibition of life, nobile flower etc.；Stem is straight Vertical, meat shape is plump, and slightly flat cylinder is long 10-60 centimetres, slightly up to 1.3 centimetres.Medicinal plant, property slightly sweet flavor is micro- salty, trembles with fear, Return stomach, kidney, lung channel.Reinforcing stomach reg fluid, nourishing Yin and clearing heat.For impairment of yin body fluid deficiency, dry polydipsia, deficiency of food is retched, after being ill abnormal heat, and mesh is secretly not It is bright.

Momordica grosvenori：The fruit of the perennial liana of Curcurbitaceae, its primary efficacy is can be relieving cough and reducing sputum.Fruits nutrition is worth It is very high, containing abundant vitamin C（Contain 400 milligrams~500 milligrams in every 100 grams of fresh fruits）And glucoside, fructose, glucose, egg White matter, lipid etc..

Embodiment

Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will Understand, the following example is merely to illustrate the present invention, and should not be taken as limiting the scope of the invention.

Embodiment 1

Stir-baked FLOS SOPHORAE IMMATURUS 100kg, Qingqian Willow leaf 40kg, Chinese Fevervine Herb 20kg, ginkgo leaf 10kg, radix polygonati officinalis 10kg, kwan-yin tea 10kg, Agrimony 10 kg, the kg of Momordica grosvenori 12.

Embodiment 2

Stir-baked FLOS SOPHORAE IMMATURUS 100kg, Qingqian Willow leaf 35kg, Chinese Fevervine Herb 25kg, ginkgo leaf 10kg, radix polygonati officinalis 10kg, kwan-yin tea 10kg, Agrimony 10 kg, the kg of Momordica grosvenori 12.

Embodiment 3

Stir-baked FLOS SOPHORAE IMMATURUS 100kg, Qingqian Willow leaf 45kg, Chinese Fevervine Herb 15kg, ginkgo leaf 9kg, radix polygonati officinalis 11kg, kwan-yin tea 11kg, Agrimony 9 Kg, the kg of Momordica grosvenori 15.

Embodiment 4

Stir-baked FLOS SOPHORAE IMMATURUS 100kg, Qingqian Willow leaf 38kg, Chinese Fevervine Herb 22kg, ginkgo leaf 9kg, radix polygonati officinalis 11kg, kwan-yin tea 9kg, Agrimony 11 Kg, the kg of Momordica grosvenori 15.

Embodiment 5

Stir-baked FLOS SOPHORAE IMMATURUS 100kg, Qingqian Willow leaf 42kg, Chinese Fevervine Herb 18kg, ginkgo leaf 7kg, radix polygonati officinalis 13kg, kwan-yin tea 7kg, Agrimony 13 Kg, the kg of Momordica grosvenori 16.

Embodiment 6

Stir-baked FLOS SOPHORAE IMMATURUS 100kg, Qingqian Willow leaf 43kg, Chinese Fevervine Herb 17kg, ginkgo leaf 12kg, radix polygonati officinalis 11kg, kwan-yin tea 13kg, Agrimony 14 kg, the kg of Momordica grosvenori 14.

Embodiment 7

Stir-baked FLOS SOPHORAE IMMATURUS 100kg, Qingqian Willow leaf 37kg, Chinese Fevervine Herb 27kg, ginkgo leaf 14kg, radix polygonati officinalis 13kg, kwan-yin tea 17kg, Agrimony 15 kg, Momordica grosvenori 12kg.

Embodiment 8

Stir-baked FLOS SOPHORAE IMMATURUS 100kg, Qingqian Willow leaf 40kg, Chinese Fevervine Herb 20kg, ginkgo leaf 8kg, radix polygonati officinalis 15kg, kwan-yin tea 15kg, Agrimony 9 Kg, Momordica grosvenori 13kg.

Embodiment 9

Stir-baked FLOS SOPHORAE IMMATURUS 100kg, Qingqian Willow leaf 40kg, Chinese Fevervine Herb 20kg, ginkgo leaf 10kg, radix polygonati officinalis 10kg, kwan-yin tea 10kg, Agrimony 10 kg, acanthopanax 17 kg, Momordica grosvenori 13kg.

Embodiment 10

Stir-baked FLOS SOPHORAE IMMATURUS 100kg, Qingqian Willow leaf 40kg, Chinese Fevervine Herb 20kg, ginkgo leaf 10kg, radix polygonati officinalis 10kg, kwan-yin tea 10kg, Agrimony 10 kg, stem of noble dendrobium leaf 5 kg, Momordica grosvenori 13kg.

Embodiment 11

Stir-baked FLOS SOPHORAE IMMATURUS 100kg, Qingqian Willow leaf 40kg, Chinese Fevervine Herb 20kg, ginkgo leaf 10kg, radix polygonati officinalis 10kg, kwan-yin tea 10kg, Agrimony 15 kg, the kg of acanthopanax 17, stem of noble dendrobium leaf 5 kg, Momordica grosvenori 15kg.

Embodiment 12

Stir-baked FLOS SOPHORAE IMMATURUS 100kg, Qingqian Willow leaf 40kg, Chinese Fevervine Herb 20kg, ginkgo leaf 10kg, radix polygonati officinalis 10kg, kwan-yin tea 10kg, Agrimony 15 kg, the kg of acanthopanax 19, stem of noble dendrobium leaf 7 kg, Momordica grosvenori 15kg.

Comparative example 1

Stir-baked FLOS SOPHORAE IMMATURUS 100kg, Qingqian Willow leaf 10kg, Chinese Fevervine Herb 20kg, ginkgo leaf 10kg, radix polygonati officinalis 10kg, kwan-yin tea 10kg, Agrimony 15 kg, the kg of acanthopanax 17, stem of noble dendrobium leaf 5 kg, Momordica grosvenori 15kg.

Comparative example 1 reduces the dosage of Qingqian Willow leaf on the basis of embodiment 11, and preparation method is the same as embodiment 11.

Comparative example 2

Comparative example 2 eliminates Qingqian Willow leaf on the basis of embodiment 11, and preparation method is the same as embodiment 11.

Embodiment, comparative example preparation method are as follows：

（1）The raw material weighed up is put into decocting container, adds water, boiled rear slow fire is decocted 30 minutes, maintains boiling water；Its The weight ratio of middle Chinese medicine material and water is 1:4；

（2）By well-done medical filtration；It is filling.

The sophora bud Chinese medicine composition of present invention treatment diabetes is found that it has blood sugar reducing function for animal experiment, and And be free from side effects, then it is used for clinical test.

The using effect of above example and comparative example is as follows.

(1) hyperglycemia patient using effect:

Fasting blood-glucose is more than 6, and postprandial blood sugar is more than or equal to 7.7 can say it is hyperglycaemia, will be not reaching to diabetes standard The people of hyperglycemia patient 140, is equally divided into 14 groups, every group of 10 people, takes embodiment 1-12 and comparative example 1-2 treatment glycosuria respectively The sophora bud Chinese medicine composition of disease, the sophora bud Chinese medicine composition instructions of taking of present invention treatment diabetes are as follows：Warmly take 3 times a day, Each 100ml, diet do not limit, and are usual diet, and after half a year, embodiment 1-12 Fasting Glucose and postprandial blood sugar is complete Portion recovers normal, and comparative example 1 has 5 to recover normal, and comparative example 2 has 4 to recover normal.

(2) type 1 diabetes people using effect:

From the ineffective diabetic of 140 conventional medicine controls sugar of hospitalization, above patient is equally divided into 14 groups, Every group of 10 people, treating insulin injection 3 times a day before could control blood glucose normal, take embodiment 1-12 and right respectively later The sophora bud Chinese medicine composition of ratio 1-2 treatment diabetes, warmly takes 3 times a day, and each 100ml, diet is diabetic diet, often Its 2 insulin injections, after 2 months, it is discontinued 1 week, determines fasting blood-glucose, 2h-plasma glucose respectively, the results are shown in Table 1.

1 14 groups of patients of table drink front and rear clinic and laboratory data

。

As it can be seen from table 1 after embodiment 11-12 patient drinks 2 months, effect is best, fasting blood-glucose substantially close to Normally, postprandial 2 hours blood glucose is also higher.

Embodiment 11-12 patient continues after drinking 1 month, and insulin injects 1 can and controls blood glucose normal daily, It is further continued for after drinking 5 months, insulin stops injection, continues to drink the sophora bud Chinese medicine composition for the treatment of diabetes, fasting blood-glucose It is normal with postprandial blood sugar.

2 times a day, postprandial blood sugar is higher for injection of insulin after embodiment 1-10 patient drinks 2 months, continues to drink 1 After month, injection of insulin 1 time a day, can control blood glucose normal, continue after drinking 8 months, and insulin stops injection, and blood glucose is normal The symptom such as every group of 3-5 example of patient, other patient main suit's giddy, tinnitus, uncomfortable in chest, shortness of breath, insomnias disappear, but insulin stop Injection, blood glucose or higher, then 1 insulin of injection daily, while quote Chinese medicine composition of the present invention and can control blood glucose just Often.

After the patient of comparative example 1 drinks 2 months, 2 blood glucose of injection of insulin can not control normally, it is also necessary to inject 3 times , continue after taking 9 months, 2 blood glucose of injection of insulin can control normally.

After the patient of comparative example 2 drinks 2 months, 2 blood glucose of injection of insulin can not control normally, it is also necessary to inject 3 times , continue after taking 12 months, 2 blood glucose of injection of insulin could control normally.

Claims (10)

1. a kind of sophora bud Chinese medicine composition for treating diabetes, it is characterised in that in terms of parts by weight, raw material includes following composition： 100 parts of stir-baked FLOS SOPHORAE IMMATURUS, Qingqian Willow leaf 20-50 parts, Chinese Fevervine Herb 15-30 parts, ginkgo leaf 5-15 parts, radix polygonati officinalis 5-15 parts, kwan-yin tea 5-20 Part, Agrimony 5-15 parts, Momordica grosvenori 10-20 parts.

2. the sophora bud Chinese medicine composition for the treatment of diabetes according to claim 1, it is characterised in that described Qingqian Willow leaf For 35-50 parts.

3. the sophora bud Chinese medicine composition for the treatment of diabetes according to claim 1, it is characterised in that described Chinese Fevervine Herb is 20-25 parts.

4. the sophora bud Chinese medicine composition for the treatment of diabetes according to claim 1, it is characterised in that described ginkgo leaf is 10-15 parts.

5. the sophora bud Chinese medicine composition for the treatment of diabetes according to claim 1, it is characterised in that described radix polygonati officinalis is 5- 10 parts.

6. the sophora bud Chinese medicine composition for the treatment of diabetes according to claim 1, it is characterised in that described kwan-yin tea is 7-15 parts.

7. the sophora bud Chinese medicine composition for the treatment of diabetes according to claim 1, it is characterised in that described Agrimony is 10-15 parts.

8. the sophora bud Chinese medicine composition for the treatment of diabetes according to claim 1, it is characterised in that also including acanthopanax 10-20 parts.

9. the sophora bud Chinese medicine composition for the treatment of diabetes according to claim 1, it is characterised in that also including stem of noble dendrobium leaf 5-9 Part.

10. the preparation method of the sophora bud Chinese medicine composition of diabetes is treated according to claim 1, it is characterised in that wrap successively Include following steps：

（1）The raw material weighed up is put into decocting container, adds water, boiled rear slow fire is decocted 20-40 minutes, and maintenance boiling water is Can；Wherein the weight ratio of Chinese medicine material and water is 1:（3-5）；

（2）By well-done medical filtration；It is filling.