CN107595857A - 用于眼部疾病和病症的组合物和治疗 - Google Patents
用于眼部疾病和病症的组合物和治疗 Download PDFInfo
- Publication number
- CN107595857A CN107595857A CN201710063950.2A CN201710063950A CN107595857A CN 107595857 A CN107595857 A CN 107595857A CN 201710063950 A CN201710063950 A CN 201710063950A CN 107595857 A CN107595857 A CN 107595857A
- Authority
- CN
- China
- Prior art keywords
- progesterone
- use according
- patient
- composition
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261676530P | 2012-07-27 | 2012-07-27 | |
| US61/676,530 | 2012-07-27 | ||
| US201361756321P | 2013-01-24 | 2013-01-24 | |
| US61/756,321 | 2013-01-24 | ||
| CN201380039713.2A CN104661663A (zh) | 2012-07-27 | 2013-07-26 | 用于眼部疾病和病症的组合物和治疗 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380039713.2A Division CN104661663A (zh) | 2012-07-27 | 2013-07-26 | 用于眼部疾病和病症的组合物和治疗 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107595857A true CN107595857A (zh) | 2018-01-19 |
Family
ID=49997851
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710063950.2A Pending CN107595857A (zh) | 2012-07-27 | 2013-07-26 | 用于眼部疾病和病症的组合物和治疗 |
| CN201380039713.2A Pending CN104661663A (zh) | 2012-07-27 | 2013-07-26 | 用于眼部疾病和病症的组合物和治疗 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380039713.2A Pending CN104661663A (zh) | 2012-07-27 | 2013-07-26 | 用于眼部疾病和病症的组合物和治疗 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US20150216877A1 (https=) |
| EP (1) | EP2877184B1 (https=) |
| JP (1) | JP6209777B2 (https=) |
| KR (1) | KR102097663B1 (https=) |
| CN (2) | CN107595857A (https=) |
| AU (1) | AU2013295645B2 (https=) |
| BR (1) | BR112015001847A8 (https=) |
| CA (1) | CA2880027C (https=) |
| DK (1) | DK2877184T3 (https=) |
| ES (1) | ES2759781T3 (https=) |
| HU (1) | HUE046963T2 (https=) |
| IL (1) | IL236920B (https=) |
| IN (1) | IN2015DN00542A (https=) |
| MX (1) | MX362185B (https=) |
| NZ (1) | NZ704247A (https=) |
| PL (1) | PL2877184T3 (https=) |
| PT (1) | PT2877184T (https=) |
| SM (1) | SMT201900678T1 (https=) |
| WO (1) | WO2014018856A1 (https=) |
| ZA (1) | ZA201500561B (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| BR112014012444B1 (pt) | 2011-11-23 | 2021-12-14 | Therapeuticsmd, Inc | Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| ES2649730T3 (es) | 2013-03-15 | 2018-01-15 | Glia Llc | Distribución craneal de compuestos farmacéuticos |
| WO2015080758A1 (en) * | 2013-11-27 | 2015-06-04 | Al-Qahtani Ahmed H | Method and composition for the treatment of moderate to severe keratoconjunctivitis sicca |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| EP3171872B1 (en) | 2014-07-21 | 2020-11-11 | Glia, LLC | Method for treating radiotherapy-and-chemotherapy associated cognitive or emotional impairment with cannabinoids |
| RU2016141135A (ru) | 2014-07-29 | 2018-08-28 | Терапьютиксмд, Инк. | Трансдермальный крем |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| KR101960023B1 (ko) * | 2016-12-21 | 2019-03-20 | 김보경 | 이산화탄소 발생 장치 |
| WO2021163253A1 (en) * | 2020-02-12 | 2021-08-19 | Glia, Llc | Progesterone combinations |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100016264A1 (en) * | 2007-12-05 | 2010-01-21 | Connor Charles G | Treatment for dry eye using testosterone and progestagen |
| CN101757622A (zh) * | 2008-11-28 | 2010-06-30 | 天津金耀集团有限公司 | 一种眼部抗炎的药物组合物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5102656A (en) | 1983-07-29 | 1992-04-07 | The Mennen Company | Antiperspirant creams |
| US4937069A (en) | 1985-11-15 | 1990-06-26 | Bristol-Myers Squibb Company | Anhydrous semi-solid antiperspirant suspension |
| US5069897A (en) | 1987-10-16 | 1991-12-03 | The Proctor & Gamble Company | Antiperspirant creams |
| US6659985B2 (en) | 2002-01-30 | 2003-12-09 | Southern College Of Optometry | Method to use transdermal administration of androgens to the adnexa of the eye |
| US7572780B2 (en) * | 2003-01-21 | 2009-08-11 | Dimera, Incorporated | Method and kit for reducing the symptoms of peripheral vascular disease |
| US20080132475A1 (en) * | 2006-12-05 | 2008-06-05 | Charles Gerald Connor | Treatment for dry eye |
| NZ584275A (en) * | 2007-10-08 | 2012-06-29 | Fovea Pharmaceuticals | Aqueous cyclosporine ophthalmic formulations |
| US10029013B2 (en) * | 2009-10-02 | 2018-07-24 | Foamix Pharmaceuticals Ltd. | Surfactant-free, water-free formable composition and breakable foams and their uses |
-
2013
- 2013-07-26 PT PT138234851T patent/PT2877184T/pt unknown
- 2013-07-26 HU HUE13823485A patent/HUE046963T2/hu unknown
- 2013-07-26 PL PL13823485T patent/PL2877184T3/pl unknown
- 2013-07-26 SM SM20190678T patent/SMT201900678T1/it unknown
- 2013-07-26 EP EP13823485.1A patent/EP2877184B1/en active Active
- 2013-07-26 CN CN201710063950.2A patent/CN107595857A/zh active Pending
- 2013-07-26 CA CA2880027A patent/CA2880027C/en active Active
- 2013-07-26 WO PCT/US2013/052264 patent/WO2014018856A1/en not_active Ceased
- 2013-07-26 ES ES13823485T patent/ES2759781T3/es active Active
- 2013-07-26 IN IN542DEN2015 patent/IN2015DN00542A/en unknown
- 2013-07-26 CN CN201380039713.2A patent/CN104661663A/zh active Pending
- 2013-07-26 KR KR1020157004782A patent/KR102097663B1/ko active Active
- 2013-07-26 NZ NZ704247A patent/NZ704247A/en unknown
- 2013-07-26 JP JP2015524465A patent/JP6209777B2/ja active Active
- 2013-07-26 AU AU2013295645A patent/AU2013295645B2/en active Active
- 2013-07-26 DK DK13823485T patent/DK2877184T3/da active
- 2013-07-26 MX MX2015001250A patent/MX362185B/es active IP Right Grant
- 2013-07-26 US US14/417,640 patent/US20150216877A1/en not_active Abandoned
- 2013-07-26 BR BR112015001847A patent/BR112015001847A8/pt not_active Application Discontinuation
-
2015
- 2015-01-25 IL IL236920A patent/IL236920B/en active IP Right Grant
- 2015-01-26 ZA ZA2015/00561A patent/ZA201500561B/en unknown
-
2016
- 2016-12-15 US US15/380,741 patent/US9925201B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100016264A1 (en) * | 2007-12-05 | 2010-01-21 | Connor Charles G | Treatment for dry eye using testosterone and progestagen |
| CN101757622A (zh) * | 2008-11-28 | 2010-06-30 | 天津金耀集团有限公司 | 一种眼部抗炎的药物组合物 |
Non-Patent Citations (1)
| Title |
|---|
| 杨文等主编: "《老年医学分册 下》", 31 December 2010, 吉林大学出版社 * |
Also Published As
| Publication number | Publication date |
|---|---|
| PL2877184T3 (pl) | 2020-04-30 |
| IL236920B (en) | 2018-06-28 |
| HUE046963T2 (hu) | 2020-04-28 |
| HK1210968A1 (en) | 2016-05-13 |
| PT2877184T (pt) | 2019-12-02 |
| ZA201500561B (en) | 2016-04-28 |
| JP6209777B2 (ja) | 2017-10-11 |
| EP2877184A1 (en) | 2015-06-03 |
| ES2759781T3 (es) | 2020-05-12 |
| EP2877184A4 (en) | 2016-03-30 |
| DK2877184T3 (da) | 2019-12-09 |
| NZ704247A (en) | 2018-04-27 |
| CN104661663A (zh) | 2015-05-27 |
| AU2013295645B2 (en) | 2017-08-24 |
| MX2015001250A (es) | 2015-10-22 |
| KR20150038311A (ko) | 2015-04-08 |
| AU2013295645A1 (en) | 2015-02-05 |
| US20170189413A1 (en) | 2017-07-06 |
| WO2014018856A1 (en) | 2014-01-30 |
| SMT201900678T1 (it) | 2020-03-13 |
| US9925201B2 (en) | 2018-03-27 |
| BR112015001847A8 (pt) | 2021-09-08 |
| MX362185B (es) | 2019-01-08 |
| JP2015524434A (ja) | 2015-08-24 |
| IN2015DN00542A (https=) | 2015-06-26 |
| BR112015001847A2 (pt) | 2017-07-04 |
| KR102097663B1 (ko) | 2020-04-06 |
| EP2877184B1 (en) | 2019-09-04 |
| US20150216877A1 (en) | 2015-08-06 |
| CA2880027A1 (en) | 2014-01-30 |
| CA2880027C (en) | 2021-12-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180119 |