CN107582209A - A kind of experimental animal vein detaining needle for fluids infusion device - Google Patents

A kind of experimental animal vein detaining needle for fluids infusion device Download PDF

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Publication number
CN107582209A
CN107582209A CN201710983126.9A CN201710983126A CN107582209A CN 107582209 A CN107582209 A CN 107582209A CN 201710983126 A CN201710983126 A CN 201710983126A CN 107582209 A CN107582209 A CN 107582209A
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CN
China
Prior art keywords
conduit
infusion device
connecting tube
experimental animal
detaining needle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710983126.9A
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Chinese (zh)
Inventor
张绍东
李菁
王彬彬
刘松
王世炜
万虹
历俊华
冯洁
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Beijing Neurosurgical Institute
Original Assignee
Beijing Neurosurgical Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Neurosurgical Institute filed Critical Beijing Neurosurgical Institute
Priority to CN201710983126.9A priority Critical patent/CN107582209A/en
Publication of CN107582209A publication Critical patent/CN107582209A/en
Priority to PCT/CN2018/076926 priority patent/WO2019075974A1/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The invention discloses a kind of experimental animal vein detaining needle for fluids infusion device, the infusion device is the tubular cavity structure of one end closing, including:Conduit, connecting tube and closure.The apparatus structure of the present invention is simple;Only need to once perform the operation can complete to insert, easy to operate, and success rate is high;Rat only needs once to perform the operation, and damage is small;Whole device is completely in subcutaneously, and postoperative the care of animal is simple, few intercurrent disease.

Description

A kind of experimental animal vein detaining needle for fluids infusion device
Technical field
The present invention relates to Medical Devices, more particularly, to a kind of experimental animal vein detaining needle for fluids infusion device, transfusion dress Put and be applied to any experimental animal, including but not limited to rabbit, dog, rat etc..
Background technology
Experimental animal (rat) vena jugularis externa tube placing operation is widely used in zoopery, for intravenous (IV) drug or is taken Blood.Find by literature search, although guide-tube structure there are a variety of changes, essential characteristic and operation technique are similar:Conduit is The deformation of the tubule or tubule of both ends open.One end of conduit carries out vena jugularis externa intubation, will be quiet outside one section of insertion neck of indwelling tube Arteries and veins, and ligature fixation;The other end of conduit is channeled from subcutaneously passing through, and passes animal nape is transdermal, is fixed on muscle groups Knit with skin.The mouth of pipe of conduit one end in vitro is closed using closure.When injecting medicine or blood drawing, closing is opened Thing, closure is put back to again after end operation.
By taking rat as an example, current rat vena jugularis externa tube placing operation needs two operations to complete.
Operation for the first time is rat vena jugularis externa intubation:By rat anesthesia, lie on the back and be placed on operating table, in neck median line Side cuts skin, exposure vena jugularis externa.Vena jugularis externa distal end is ligatured, and burns and closes side shoot vein.A kerf is done on vein, The conduit of preliminary filling heparin is inserted from cutting section centripetal direction, insertion depth about 2.5cm.Vena jugularis externa ligatures A/C, uses Syringe is pushed into salt solution from the other end, checks that pipeline is unobstructed.
Second of operation is that rat is positioned into prone position, the osculum of incision of skin one after neck, by conduit free-end through drawing Lead through subcutaneously being passed from this otch, muscle of back tissue and skin are fixed in suture.Intercept the conduit of suitable length, sealed tube Mouthful.
By being operated more than observing, it can be found that prior art has a disadvantage that:
1st, need to carry out two operations in animals, expend time length, it is big to animal injury;
2nd, it is PEG tube or epidural catheter to use conduit, relatively hard, pliability deficiency, in the blood vessels, subcutaneous row Need to repeatedly it be bent when walking, tension force is very big, easily pierces through blood vessel, or deviates from from blood vessel, and such case is external at back Section is more easy to occur by during larger external force or when carrying out injection operation;
3rd, the conduit exposed to nape part is a foreign matter to animal, easily causes the scratching of animal, easy displacement, comes off, Animal wound also easily infects;
4th, conduit is stung, it is necessary to which animal is individually raised in order to prevent animal from biting mutually, increase the care of animal cost;
5th, operation is completed to need patient to have quite skilled operation skill, and it is higher to complete difficulty.
Therefore, it is necessary to a kind of improved experimental animal (such as rat) vena jugularis externa retention transfusion device.
The content of the invention
It is an object of the invention to provide a kind of experimental animal vena jugularis externa retention transfusion device.
A kind of experimental animal vein (including but is not limited to vena jugularis externa) retention transfusion device, the infusion device is one end The tubular cavity structure of closing, including:
Conduit, the conduit are straight tubular structure or bent tube form structure, have the can be plugged into vena jugularis externa A part and the Part II that can be connected with connecting tube;
Connecting tube, the connecting tube are the different tubular structures of both ends nozzle diameter, the nozzle diameter of the connecting tube compared with Small one end is connected with the Part II of the conduit;And
Closure, the closure are arranged on larger one end of nozzle diameter of the connecting tube to close the mouth of pipe, and The closure is transparent.
Further, the conduit is bent tube form structure, has angle between the Part I and Part II.This Kind structure is more suitable for rat use.Preferably, the conduit is L-shaped tubular structure.
The external diameter of conduit meets that it can be plugged into vein.Further, the conduit length meet be inserted into it is quiet Still it is partially in after arteries and veins 2-2.5cm outside blood vessel.Preferably, the length of the conduit is more than 3cm.
Further, the conduit is provided with the scale for being used for indicating length.Preferably, the conduit is in its Part I The scale for being used for indicating length is provided with from the mouth of pipe.It is highly preferred that the conduit its Part I from the mouth of pipe 1cm, There is scale mark at 2cm, 3cm.
Further, the nozzle diameter of the connecting tube is be gradually increased to be relatively large in diameter from the less one end of diameter one End.
The closure is that have closing function and can penetrate the part of function, for example, latex cap, silicon rubber cup or rubber The analogs such as plug.
The present invention has advantages below:
The experimental animal of the present invention solves multiple shortcomings of prior art with vein detaining needle for fluids infusion device, it is possible to achieve dynamic The long-term intravenous infusion treatment of thing;Whole device is only made up of 3 parts, simple in construction;Only need to once perform the operation can complete to insert, Easy to operate, success rate is high;Animal only needs once to perform the operation, and damage is small;Whole device is completely in subcutaneously, postoperative the care of animal Simply, few intercurrent disease.
Brief description of the drawings
Fig. 1 is the structural representation of the experimental animal vein detaining needle for fluids infusion device of the present invention.
Fig. 2 is a kind of structural representation of experimental animal preferred embodiment of vein detaining needle for fluids infusion device of the present invention.
Embodiment
Embodiment
As shown in figure 1, it is the structural representation of the experimental animal vein detaining needle for fluids infusion device of the present invention.The device is one The tubular structure thing that end seal is closed, including conduit 1, connecting tube 2 and silicon rubber cup 3.
Conduit 1 is straight tubular structure, has the Part I 11 that can be plugged into vein and can be connected with connecting tube Part II 12.The external diameter of conduit 1 meets that it can be plugged into vein, and overall length is more than 3cm.From pipe on Part I 11 Oral end is risen scale mark 4 at 1cm, 2cm, 3cm.
Connecting tube 2 is the tubular structure with first mouth of pipe 21 and second mouth of pipe 22, from first 21 to the second mouth of pipe of the mouth of pipe 22 nozzle diameter gradually increases.First mouth of pipe 21 is connected with the part of Part II 12 of conduit 1.The internal diameter of connecting tube 2 is more than The external diameter of conduit 1, to reduce venipuncture difficulty.
Silicon rubber cup 3 is covered at second mouth of pipe 22 of connecting tube 2, for closing vein detaining catheter and can be worn as vein Thorn, the path for realizing intravenous injection.Silicon rubber cup 3 can be replaced with analogs such as latex cap, rubber stoppers.
As shown in Fig. 2 in a preferred embodiment, conduit 1 is L-shaped bent tube form structure, it is more suitable for rat use.
Now the specific operation process of the vein detaining needle for fluids infusion device is described as follows with rat citing:
1st, vein detaining needle for fluids infusion device needed for preparing, injects heparin-saline, by vein detaining needle for fluids infusion at silicon rubber cup 3 Device is full of, standby.
2nd, it will be in dorsal position after rat anesthesia, skin cut on the right side of cervical midline, separate manadesma, expose vena jugularis externa, Vena jugularis externa distal end ligatures, and burns the side shoot vein closed to vena jugularis externa blood supply.Vena jugularis externa proximal part is ligatured with silk thread, and In advance loosely make a call to two knots.Between ligaturing at two, a kerf is cut on vein with microscissors, size is can be put into Conduit 1 is defined.Conduit 1 is accurately extend into vena jugularis externa, blood vessel and conduit 1 are fixed with reserved knot.It is quiet to open ligation The knot of arteries and veins, by conduit 1 slightly again into blood vessel it is deeper.
3rd, changing rat figure makes it be in lateral position, and surgical clamp is stretched into neck dorsal part from cervical incision, separates rat neck Portion's skin and muscle, after obtaining sufficient space, connecting tube 2 is sent into subcutaneous space from cut out portion, it is defeated to adjust the venous indwelling The position of liquid device, conduit 1 is inserted to vein proximal part again, insertion depth 2-2.5cm, connecting tube 2 is adjusted to big After mouse ear, in erectility.Suture skin of neck.Skin is passed through from rat nape part, silicon rubber cup 3 is penetrated and is injected.If Operation is normal, it should injects much smoother.
Those listed above is a series of to be described in detail only for feasibility embodiment of the invention specifically Bright, they simultaneously are not used to limit the scope of the invention, those skilled in the art can be designed that a lot of other modifications and Embodiment, these modifications and embodiment will fall within spirit disclosed in the present application and spirit.More specifically, exist In the range of disclosure, drawings and claims, the building block and/or layout of theme combination layout can be carried out more Kind variations and modifications.In addition to the variations and modifications carried out to building block and/or layout, come for those skilled in the art Say, other purposes also will be apparent.

Claims (10)

1. a kind of experimental animal vein detaining needle for fluids infusion device, it is characterised in that the infusion device is that the tubulose of one end closing is empty Cavity configuration, including:
Conduit, the conduit are straight tubular structure or bent tube form structure, have first can be plugged into vena jugularis externa The Part II that divides and can be connected with connecting tube;
Connecting tube, the connecting tube are the different tubular structures of both ends nozzle diameter, and the nozzle diameter of the connecting tube is less One end is connected with the Part II of the conduit;And
Closure, the closure are arranged on larger one end of nozzle diameter of the connecting tube to close the mouth of pipe, and described Closure is transparent.
2. a kind of experimental animal vein detaining needle for fluids infusion device according to claim 1, it is characterised in that the conduit is Bent tube form structure, there is angle between the Part I and Part II.
3. a kind of experimental animal vein detaining needle for fluids infusion device according to claim 2, it is characterised in that the conduit is L-shaped tubular structure.
4. a kind of experimental animal vein detaining needle for fluids infusion device according to claim 1, it is characterised in that the conduit Length meets still to be partially in outside blood vessel after vena jugularis externa 2-2.5cm is inserted into.
5. a kind of experimental animal vein detaining needle for fluids infusion device according to claim 1 or 2, it is characterised in that described to lead Pipe is provided with the scale for being used for indicating length.
6. a kind of experimental animal vein detaining needle for fluids infusion device according to claim 5, it is characterised in that the conduit exists Its Part I is provided with the scale for being used for indicating length from the mouth of pipe.
7. a kind of experimental animal vein detaining needle for fluids infusion device according to claim 6, it is characterised in that the conduit exists Its Part I has scale mark from the mouth of pipe at 1cm, 2cm, 3cm.
A kind of 8. experimental animal vein detaining needle for fluids infusion device according to claim 1 or 2, it is characterised in that the company The nozzle diameter of adapter is to be gradually increased to one end for being relatively large in diameter from the less one end of diameter.
A kind of 9. experimental animal vein detaining needle for fluids infusion device according to claim 1 or 2, it is characterised in that the envelope It is latex cap, silicon rubber cup or rubber stopper to close thing.
10. a kind of rat vena jugularis externa retention transfusion device, it is characterised in that the infusion device is that the tubulose of one end closing is empty Cavity configuration, including:
Conduit, the conduit are bent tube form structures, have the Part I that can be plugged into vena jugularis externa and can be with connecting tube Connected Part II, there is angle between two parts;
Connecting tube, the connecting tube are the different tubular structures of both ends nozzle diameter, and the nozzle diameter of the connecting tube is less One end is connected with the Part II of the conduit;And
Closure, the closure are arranged on larger one end of nozzle diameter of the connecting tube to close the mouth of pipe, and described Closure is transparent.
CN201710983126.9A 2017-10-19 2017-10-19 A kind of experimental animal vein detaining needle for fluids infusion device Pending CN107582209A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201710983126.9A CN107582209A (en) 2017-10-19 2017-10-19 A kind of experimental animal vein detaining needle for fluids infusion device
PCT/CN2018/076926 WO2019075974A1 (en) 2017-10-19 2018-02-20 Venous indwelling infusion device for animals

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710983126.9A CN107582209A (en) 2017-10-19 2017-10-19 A kind of experimental animal vein detaining needle for fluids infusion device

Publications (1)

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CN107582209A true CN107582209A (en) 2018-01-16

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WO (1) WO2019075974A1 (en)

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN85200247U (en) * 1985-04-02 1985-09-10 吴承远 Intravenous catheter of double pathes with closed diaphragms
CN85200245U (en) * 1985-04-02 1986-01-15 翟允 Infusion guide tube able to be left in the vein of human body for a long time
CN2123338U (en) * 1991-12-18 1992-12-02 赵雄远 Needle for stayed in human body for infusion and blood introduction
CN2275454Y (en) * 1996-08-12 1998-03-04 王克煌 Arteriovenous needle
CN2330314Y (en) * 1998-08-06 1999-07-28 陈宝平 Dialysis non-return trocar
US6033393A (en) * 1996-12-31 2000-03-07 Johnson & Johnson Medical, Inc. Method and apparatus for overpressure protection of a catheter
CN201578340U (en) * 2009-08-07 2010-09-15 杨军 Arc-shaped venipuncture remaining needle
CN202185012U (en) * 2011-07-29 2012-04-11 成都市新津事丰医疗器械有限公司 Venous retention needle without heparin cap and guide tube seat thereof
CN205107968U (en) * 2015-11-16 2016-03-30 上海交通大学医学院附属瑞金医院 Infusion set is kept somewhere to rat jugular vein
CN205866893U (en) * 2016-06-01 2017-01-11 昆明医科大学 Needle device is kept somewhere in injection of rat mouse caudal vein

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004097524A (en) * 2002-09-10 2004-04-02 Enomoto Co Ltd Medical appliance and animal treating appliance
JP2004000374A (en) * 2002-06-03 2004-01-08 Enomoto Co Ltd Needle for catheter
JP2007075406A (en) * 2005-09-15 2007-03-29 Enomoto Co Ltd Medical appliance
CN2933433Y (en) * 2006-07-27 2007-08-15 徐永 Syringe for veterinary surgeon
CN102028557A (en) * 2011-01-11 2011-04-27 宁波大学 Intravenous self-administration jugular intubator and animal model construction method by using same

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN85200247U (en) * 1985-04-02 1985-09-10 吴承远 Intravenous catheter of double pathes with closed diaphragms
CN85200245U (en) * 1985-04-02 1986-01-15 翟允 Infusion guide tube able to be left in the vein of human body for a long time
CN2123338U (en) * 1991-12-18 1992-12-02 赵雄远 Needle for stayed in human body for infusion and blood introduction
CN2275454Y (en) * 1996-08-12 1998-03-04 王克煌 Arteriovenous needle
US6033393A (en) * 1996-12-31 2000-03-07 Johnson & Johnson Medical, Inc. Method and apparatus for overpressure protection of a catheter
DE69724579T2 (en) * 1996-12-31 2004-07-29 Ethicon, Inc. Device for protecting against excess pressure in a catheter
CN2330314Y (en) * 1998-08-06 1999-07-28 陈宝平 Dialysis non-return trocar
CN201578340U (en) * 2009-08-07 2010-09-15 杨军 Arc-shaped venipuncture remaining needle
CN202185012U (en) * 2011-07-29 2012-04-11 成都市新津事丰医疗器械有限公司 Venous retention needle without heparin cap and guide tube seat thereof
CN205107968U (en) * 2015-11-16 2016-03-30 上海交通大学医学院附属瑞金医院 Infusion set is kept somewhere to rat jugular vein
CN205866893U (en) * 2016-06-01 2017-01-11 昆明医科大学 Needle device is kept somewhere in injection of rat mouse caudal vein

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Application publication date: 20180116

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