CN107550592A - A kind of trochar applied to middle cerebral artery occlusion model - Google Patents
A kind of trochar applied to middle cerebral artery occlusion model Download PDFInfo
- Publication number
- CN107550592A CN107550592A CN201710926068.6A CN201710926068A CN107550592A CN 107550592 A CN107550592 A CN 107550592A CN 201710926068 A CN201710926068 A CN 201710926068A CN 107550592 A CN107550592 A CN 107550592A
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- China
- Prior art keywords
- closing member
- nook closing
- puncture needle
- trochar
- needle
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Links
- 206010008089 Cerebral artery occlusion Diseases 0.000 title claims abstract description 20
- 201000007309 middle cerebral artery infarction Diseases 0.000 title claims abstract description 20
- 210000004204 blood vessel Anatomy 0.000 claims abstract description 13
- 230000002792 vascular Effects 0.000 claims abstract description 4
- 230000000149 penetrating effect Effects 0.000 claims abstract description 3
- 208000005189 Embolism Diseases 0.000 claims description 13
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 10
- 239000000741 silica gel Substances 0.000 claims description 10
- 229910002027 silica gel Inorganic materials 0.000 claims description 10
- 238000003780 insertion Methods 0.000 claims description 8
- 230000037431 insertion Effects 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 6
- 239000004033 plastic Substances 0.000 claims description 5
- 229910001220 stainless steel Inorganic materials 0.000 claims description 5
- 239000010935 stainless steel Substances 0.000 claims description 5
- 230000017531 blood circulation Effects 0.000 claims description 3
- 230000000903 blocking effect Effects 0.000 claims description 2
- 230000002980 postoperative effect Effects 0.000 claims description 2
- 230000023597 hemostasis Effects 0.000 abstract description 2
- 238000010276 construction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 description 6
- 101800004637 Communis Proteins 0.000 description 5
- 230000000740 bleeding effect Effects 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 241000700159 Rattus Species 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 230000002490 cerebral effect Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 201000006474 Brain Ischemia Diseases 0.000 description 1
- 206010008120 Cerebral ischaemia Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 208000032984 Intraoperative Complications Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 238000001949 anaesthesia Methods 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 210000005013 brain tissue Anatomy 0.000 description 1
- 210000000269 carotid artery external Anatomy 0.000 description 1
- 206010008118 cerebral infarction Diseases 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 208000035474 group of disease Diseases 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
Abstract
The present invention provides a kind of trochar applied to middle cerebral artery occlusion model, belongs to medical instruments field.The trochar reusable edible, including puncture needle, nook closing member, line bolt.Puncture needle includes needle body, fixed-wing, anchor tip, and fixed-wing is fixed on the side of needle body, is connected at the top of anchor tip for taper with needle body bottom, bottom is provided with a tapered opening；Nook closing member includes nook closing member main body and fixed interface, is taper at the top of fixed interface, and its conical tapers is identical with the opening taper of anchor tip bottom, ensures that both are brought into close contact, and nook closing member is used to fix single unit system, plays a part of stopping blooding and prevents puncture needle from penetrating blood vessel；Line bolt is commercially available structure.Puncture needle is used for intravasation, and nook closing member is pushed into puncture needle, prevents spike pierces blood vessel, line bolt is inserted through nook closing member to target vascular site.The simple in construction, simple operation of the present invention, low cost, puncture needle intravasation can simultaneously be fixed, block hemostasis.
Description
Technical field
The invention belongs to medical instruments field, is related to a kind of trochar applied to middle cerebral artery occlusion model.
Background technology
Cerebral apoplexy is a kind of acute cerebrovascular diseases, is due to that cerebral vessels rupture or because angiemphraxis causes blood suddenly
It cannot flow into brain and cause one group of disease of brain tissue impairment, there is the characteristics of incidence of disease is high, the death rate is high and disability rate is high.
This sick possibility pathogenesis is sought using animal model, finding effective medicine and method has great society's meaning
Justice, and the animal pathological model that foundation is stablized is this sick key link of research, wherein middle cerebral artery occlusion (MCAO) model
It is generally considered standard focal cerebral ischemia in rats.
When the modus operandi of the wired bolt of key technology of MCAO modelings, inserted mode, insertion depth, head end diameter, embolism
Between etc..At present after general anaesthesia rat, sterilization, throat skin is cut, blunt separation hypodermis, separation arteria carotis communis, in neck
Artery, vena jugularis externa, ligation arteria carotis communis proximal part, external carotid artery, internal carotid hanging wire.Folder closes arteria carotis communis distal end, uses
Eye scissors clip, insertion line bolt on arteria carotis communis, sew up the incision after ligaturing the line bolt of fixed insertion.Wherein from cut blood vessel to
Insertion line bolt to specified location is the key link of operation.Existing method, directly in arteria carotis communis upper shed, exist and cutting blood
The shortcomings that operating space is small during pipe, amount of bleeding is more, operation difficulty is big.Operation opening size is not easy to determine, excessive easily to cause blood vessel
Fracture, bleeding, too small line bolt are then not easy to insert.The problem of above, causes operating time extension, surgical injury greatly so as to cause mould
The failure of type and unstable.
The content of the invention
The problem of existing for prior art, the present invention provide a kind of sleeve pipe applied to middle cerebral artery occlusion model
Pin, the modeling that the trochar is applied to middle cerebral artery occlusion model are performed the operation.
In order to reach object above, the technical scheme is that：
A kind of trochar applied to middle cerebral artery occlusion model, the trochar reusable edible, including puncture needle 1,
Nook closing member 2, line bolt 3.Puncture needle 1 is used for intravasation, and nook closing member 2 is pushed into puncture needle 1, prevents puncture needle 1 from puncturing blood vessel, line bolt 3
Nook closing member 2 is inserted through to target vascular site.
Described puncture needle 1 is used to penetrate blood vessel, including hollow needle body 1-1, fixed-wing 1-2, anchor tip 1-3.Gu
The side that wing 1-2 is fixed on needle body 1-1 is determined, for operation and postoperative fixation；Anchor tip 1-3 is hollow cylindrical structure,
Its top is taper, and top is connected with needle body 1-1 bottoms, and bottom is provided with a tapered opening.Described puncture needle 1 is stainless steel
Material.Described anchor tip 1-3 is plastic material.Described needle body 1-1 internal diameter is 0.6-0.8mm.
Described nook closing member 2 is hollow structure, including nook closing member main body 2-1 and fixed interface 2-2.Nook closing member main body 2-1 external diameter
Less than needle body 1-1 internal diameters, length is more than needle body 1-1 length；Described fixed interface 2-2 is boss structure, is cone at the top of boss
Shape, its conical tapers is identical with the opening taper of anchor tip 1-3 bottoms, ensures that both are brought into close contact, is cylinder in the middle part of boss
Body structure, cylinder external diameter are less than anchor tip 1-3 internal diameter, and boss bottom is disc structure, and the external diameter of disc structure is more than
Anchor tip 1-3 external diameters, when inside the fully-inserted needle body 1-1 of nook closing member main body 2-1, fixed interface 2-2 is along anchor tip 1-3 bottoms
Inside portion opening insertion anchor tip 1-3, the disc structure of boss bottom plays fixation.Nook closing member 2 is used for fixed overall dress
Put, can play a part of stopping blooding and prevent puncture needle from penetrating blood vessel.Described nook closing member main body 2-1 internal diameters are 0.35-0.55mm.
Described line bolt 3 is commercially available structure, including silica gel embolus 3-1, main body 3-2.Main body 3-2 diameters are much smaller than nook closing member 2-
1 internal diameter, it is 0.22-0.28mm.Main body 3-2 tops are coated with silica gel embolus 3-1 to blocking blood flow, silica gel embolus 3-1's
Diameter is slightly less than arteria cerebri media diameter, is 0.32-0.38mm.
The device makes embolus reach the head of nook closing member 2, then nook closing member 2 is together with line bolt before use, line bolt 3 is penetrated inside nook closing member 2
3 are pushed into inside puncture needle 1, ensure the head end of nook closing member 2 apart from the head end 0.5mm of puncture needle 1.It is using process：First, puncture needle 1
Vascular wall intravasation is punctured, then nook closing member 2-1 is pushed completely into, fixed interface 2-2 rises from the insertion anchor tip 1-3 of bottom
To fixing device and the effect of reduction bleeding.Finally, line bolt 3 is slowly pushed into, adjustment angle and position in push-on process, entered
Target blood, block corresponding tissue blood flow.
The invention has the advantages that compared to existing blood vessel clip method, a portable and effective, structure are devised
Simple trochar, by puncture needle intravasation, while fix, the trochar of closure hemostasis.It compensate for current procedure operation
In the limitation of openings of sizes, amount of bleeding, operating time, operating field, the equipment suitable for MCAO models in rats is invented, there is generation
Table is strong, simple operation, low cost the features such as.
Brief description of the drawings
Fig. 1 is the overall structure diagram of trochar.
Fig. 2 is the structural representation of each part of trochar；(a) it is puncture needle, (b) is nook closing member, and (c) is line bolt.
Fig. 3 is the use schematic diagram of trochar；(a) structure chart of anterior cannula pin is used for device, (b) is that device used
The structure chart of journey middle sleeve pin, (c) are that device uses the structure chart for terminating rear sleeve pin.
Fig. 4 is the use schematic diagram of trochar insertion blood vessel；(a) structure chart during blood vessel, (b) are had just enter into for puncture needle 1
For puncture needle intravasation, structure chart when nook closing member is pushed completely into, (c) is the structure chart that line bolt 3 enters target blood.
In figure：1 puncture needle；2 nook closing members；3 line bolts；1-1 needle bodies；1-2 fixed-wings；1-3 anchor tips；2-1 nook closing member main bodys；2-
2 anchor tips；3-1 silica gel emboluses；3-2 main bodys.
Embodiment
Describe the embodiment of the present invention in detail below in conjunction with technical scheme and accompanying drawing.
A kind of trochar applied to middle cerebral artery occlusion model, including puncture needle 1, nook closing member 2, line bolt 3.
Puncture needle 1 is used to penetrate blood vessel, including hollow needle body 1-1, fixed-wing 1-2, hollow anchor tip 1-3, and three
Person is structure as a whole.Fixed-wing 1-2 is fixed on needle body 1-1 side；Anchor tip 1-3 is hollow cylindrical structure, and it is pushed up
Portion is taper, and top is connected with needle body 1-1 bottoms, and bottom is provided with a tapered opening.Described puncture needle 1 is stainless steel
Matter.Described anchor tip 1-3 is plastic material.Needle body 1-1 internal diameter is 0.7mm.Nook closing member 2 is hollow structure, including nook closing member
2-1 and fixed interface 2-2；Nook closing member 2-1 internal diameters are 0.5mm, and nook closing member 2-1 length is more than needle body 1-1 length；Described fixed interface
2-2 is boss structure, is taper at the top of boss, its conical tapers is identical with the opening taper of anchor tip 1-3 bottoms, in boss
Portion is cylindrical structure, and cylinder external diameter is less than anchor tip 1-3 external diameter, and boss bottom is disc structure, disc structure
External diameter is more than anchor tip 1-3 external diameters.Line bolt 3 is commercially available structure, including silica gel embolus 3-1, main body 3-2；Main body 3-2 is commercially available
Suppleness appropriateness nylon embolus line, its a diameter of 0.25mm, main body 3-2 tops are coated with silica gel embolus 3-1, and its is a diameter of
0.34mm。
Claims (8)
1. a kind of trochar applied to middle cerebral artery occlusion model, it is characterised in that described trochar includes puncture needle
(1), nook closing member (2), line bolt (3)；Puncture needle (1) is used for intravasation, and nook closing member (2) push-in puncture needle (1) is interior, prevents puncture needle
(1) blood vessel is punctured, line bolt (3) is inserted through nook closing member (2) to target vascular site；
Described puncture needle (1) includes hollow needle body (1-1), fixed-wing (1-2), anchor tip (1-3)；Fixed-wing (1-2)
Needle body (1-1) side is fixed on, for operation and postoperative fixation；Anchor tip (1-3) is hollow cylindrical structure, and it is pushed up
Portion is taper, and top is connected with needle body (1-1) bottom, and bottom is provided with a tapered opening；
Described nook closing member (2) is hollow structure, including nook closing member main body (2-1) and fixed interface (2-2)；Nook closing member main body (2-1) is outside
Footpath is less than needle body (1-1) internal diameter, and length is more than needle body (1-1) length；Described fixed interface (2-2) is boss structure, boss
Top is taper, and its conical tapers is identical with the opening taper of anchor tip (1-3) bottom, ensures that fixed interface (2-2) is complete
When insertion anchor tip (1-3) is interior；Nook closing member (2) is used to fix single unit system, stop blooding and prevent puncture needle from penetrating blood vessel；
Described line bolt (3) includes silica gel embolus (3-1), main body (3-2)；Main body (3-2) diameter is less than the interior of nook closing member (2) -1
Footpath；Main body (3-2) top is coated with silica gel embolus (3-1) and is less than arteria cerebri media diameter to blocking blood flow, its diameter.
2. a kind of trochar applied to middle cerebral artery occlusion model according to claim 1, it is characterised in that described
The internal diameter of needle body (1-1) be 0.6-0.8mm.
A kind of 3. trochar applied to middle cerebral artery occlusion model according to claim 1 or 2, it is characterised in that
Described nook closing member main body (2-1) internal diameter is 0.35-0.55mm.
A kind of 4. trochar applied to middle cerebral artery occlusion model according to claim 1 or 2, it is characterised in that
Described main body (3-2) internal diameter is 0.22-0.28mm；A diameter of 0.32-0.38mm of silica gel embolus (3-1).
5. a kind of trochar applied to middle cerebral artery occlusion model according to claim 3, it is characterised in that described
Main body (3-2) internal diameter be 0.22-0.28mm；A diameter of 0.32-0.38mm of silica gel embolus (3-1).
6. according to a kind of trochar applied to middle cerebral artery occlusion model described in claim 1 or 2 or 5, its feature exists
In described puncture needle (1) is stainless steel；Described anchor tip (1-3) is plastic material.
7. a kind of trochar applied to middle cerebral artery occlusion model according to claim 3, it is characterised in that described
Puncture needle (1) be stainless steel；Described anchor tip (1-3) is plastic material.
8. a kind of trochar applied to middle cerebral artery occlusion model according to claim 4, it is characterised in that described
Puncture needle (1) be stainless steel；Described anchor tip (1-3) is plastic material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710926068.6A CN107550592A (en) | 2017-10-06 | 2017-10-06 | A kind of trochar applied to middle cerebral artery occlusion model |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710926068.6A CN107550592A (en) | 2017-10-06 | 2017-10-06 | A kind of trochar applied to middle cerebral artery occlusion model |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107550592A true CN107550592A (en) | 2018-01-09 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710926068.6A Pending CN107550592A (en) | 2017-10-06 | 2017-10-06 | A kind of trochar applied to middle cerebral artery occlusion model |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110680554A (en) * | 2019-11-18 | 2020-01-14 | 上海市普陀区人民医院 | Experimental animal molding assembly for focal permanent cerebral ischemia |
| CN112545701A (en) * | 2020-12-03 | 2021-03-26 | 苏州大学 | Wire bolt, fixer, wire bolt operating device and using method |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2117132U (en) * | 1992-03-06 | 1992-09-30 | 薛向阳 | Core induced indwelling trocar |
| US20050165427A1 (en) * | 2004-01-22 | 2005-07-28 | Jahns Scott E. | Vessel sealing devices |
| CN203634150U (en) * | 2013-11-28 | 2014-06-11 | 李庆辉 | Novel arterial indwelling needle |
| CN104958097A (en) * | 2015-06-01 | 2015-10-07 | 湖南中医药大学 | Arteria carotis communis puncture needle and using method thereof |
| CN204744287U (en) * | 2015-04-07 | 2015-11-11 | 深圳市第二人民医院 | A line is tied for making big, mouse ischemic cerebral apoplexy model |
| CN208426244U (en) * | 2017-10-06 | 2019-01-25 | 大连医科大学 | A kind of trochar applied to middle cerebral artery occlusion model |
-
2017
- 2017-10-06 CN CN201710926068.6A patent/CN107550592A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2117132U (en) * | 1992-03-06 | 1992-09-30 | 薛向阳 | Core induced indwelling trocar |
| US20050165427A1 (en) * | 2004-01-22 | 2005-07-28 | Jahns Scott E. | Vessel sealing devices |
| CN203634150U (en) * | 2013-11-28 | 2014-06-11 | 李庆辉 | Novel arterial indwelling needle |
| CN204744287U (en) * | 2015-04-07 | 2015-11-11 | 深圳市第二人民医院 | A line is tied for making big, mouse ischemic cerebral apoplexy model |
| CN104958097A (en) * | 2015-06-01 | 2015-10-07 | 湖南中医药大学 | Arteria carotis communis puncture needle and using method thereof |
| CN208426244U (en) * | 2017-10-06 | 2019-01-25 | 大连医科大学 | A kind of trochar applied to middle cerebral artery occlusion model |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110680554A (en) * | 2019-11-18 | 2020-01-14 | 上海市普陀区人民医院 | Experimental animal molding assembly for focal permanent cerebral ischemia |
| CN112545701A (en) * | 2020-12-03 | 2021-03-26 | 苏州大学 | Wire bolt, fixer, wire bolt operating device and using method |
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Application publication date: 20180109 |
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