CN107543815A - A kind of test strips of matrix form distribution and the production technology and detection method of test strips - Google Patents

A kind of test strips of matrix form distribution and the production technology and detection method of test strips Download PDF

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Publication number
CN107543815A
CN107543815A CN201610523190.4A CN201610523190A CN107543815A CN 107543815 A CN107543815 A CN 107543815A CN 201610523190 A CN201610523190 A CN 201610523190A CN 107543815 A CN107543815 A CN 107543815A
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China
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test strips
paper
substrate
medicine block
rectangle
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CN201610523190.4A
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Chinese (zh)
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姜志凌
赵云
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Individual
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Individual
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  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

The present invention proposes a kind of test strips of matrix form distribution and the production technology and detection method of test strips, the shape of the substrate of test strips is rectangle, medicine block is arranged on substrate with a matrix type, the production technology of test strips has two kinds of selectable methods, it is to paste twice respectively, trimming processes and branch injecting glue mounting method three times, detection method uses fixed IMAQ, the substrate of test strips, which broadens, to shorten, medicine block, which concentrates in together, is easy to immersion liquid, it is easy to use, medicine block, which concentrates in together, allows test strips analyzer to use fixed image-pickup method, it greatly simplify the testing agency of test strips analyzer, reduce the design of test strips analyzer, production, manufacturing cost.

Description

A kind of test strips of matrix form distribution and the production technology and detection method of test strips
Technical field
The present invention relates to a kind of production technology and detection method of external reagent, specially a kind of test paper of matrix form distribution The production technology and detection method of bar and test strips.
Background technology
Test strips are a kind of external diagnosis reagents, are usually used in hospital and various medical institutions, due to by production technology system About, common test strips are soaked with the multiple of different chemical reagent by what strip substrate and the spaced linear being bonded on substrate arranged Square medicine block forms, and during production, according to the quantity of the medicine block in test strips, prepares the original paper and square of the rectangle of identical quantity The substrate of shape, dry, be stained with a face of each body paper identical after different reagents is immersed to original paper respectively The double faced adhesive tape of size, all original papers for being stained with double faced adhesive tape are cut into the wide strip body paper of 4mm, the edge on rectangle substrate Length direction presses a size identical template, parallel along its length in template to be provided with length of multiple a width of 4mm at intervals of 2mm Bar hole, the wide strip body paper glue surfaces of 4mm will be cut into and be pressed into towards substrate in the strip hole of template, the press-in of different strip holes Different reagent strip body paper are soaked with, remove template, parallel along its length be stained with a plurality of is soaked with different reagents on rectangle substrate Width is that 4mm cuts into the wide strips of 5mm at intervals of 2mm strip body paper, then by substrate along vertical sliver body paper direction, is passed through Once paste and cut final production twice and go out strip test strips, on the substrate of strip test strips spaced linear arrangement be soaked with Multiple square medicine blocks of different chemical reagent;The method for using and detecting is that all medicine blocks in test strips are immersed in into test solution In body, the different medicine blocks in test strips is chemically reacted with special component contained in the liquid of immersion, make in test strips Each piece of medicine block discoloration occurs, then test strips are placed in test strips analyzer, the moveable inspection of test strips analyzer Change colo(u)r specification of the mechanism along each piece of medicine block of test strips length direction mobile collection is surveyed, is drawn by computing corresponding to each piece of medicine block The content of special component, there is provided adjudicate foundation to tester, the medicine block of test strips common at present has 14 pieces, corresponding measurement 14 Composition, but the test strips structure of existing strip, made troubles to using with detection process, the test strips to detection are analyzed Design, production, the manufacture of instrument add cost.
The content of the invention
The purpose of the present invention is to design a kind of new test strips, to solve present test strips using the not convenient of process With the high cost of pertinent instruments production, the present invention propose a kind of test strips of matrix form distribution and the production technology of test strips with Detection method, the strip test strips arranged in a straight line more than 5 times of medicine block compare with existing length-width ratio, examination proposed by the present invention The shape of the substrate of paper slip is rectangle, and length-width ratio is less than or equal to 4 times, and medicine block is arranged on substrate with a matrix type, laterally The line number of arrangement is more than or equal to 2, and vertically disposed columns is more than or equal to 2, the medicine block quantity arranged on every row or each column More than or equal to 2, medicine block is shaped as that regular polygon rectangle is either circular, and the length of the length of side or radius is 1- 10mm, between the row of medicine block and row, the spacing that arranges between the column and the column is between 1-5mm;With the change of test paper strip, examination The production technology of paper slip has two kinds of selectable methods, be respectively paste twice, trimming processes and branch injecting glue mounting method three times; From twice paste, three times cutting process produce when, according to the quantity of the medicine block in test strips, prepare the rectangle of identical quantity Original paper, dry, be stained with a face of each body paper identical after different reagents is immersed to original paper respectively The double faced adhesive tape of size, all original papers for being stained with double faced adhesive tape are cut into the strip body paper of 4mm width, in rectangle one side gummed paper The paper without glue press the templates of upper formed objects, it is parallel in template to be provided with strips of multiple a width of 4mm at intervals of 2mm Hole, the wide strip body paper glue surfaces of 4mm will be cut into and be pressed into towards one side glue paper in the strip hole of template, remove template, rectangle It is parallel from side on one side gummed paper that to be stained with a plurality of width for being soaked with different reagents be 4mm at intervals of 2mm strip body paper, then by one side glue Paper cuts into the wide strip one side adhesive tape of 4mm along vertical sliver body paper direction, and one is pressed along its length on rectangle substrate Individual size identical template, it is parallel along its length in template to be provided with strip holes of multiple a width of 4mm at intervals of 2mm, it will cut The strip one side adhesive tape glue surface wide into 4mm is pressed into the strip hole of template towards substrate, removes template, along length on rectangle substrate Degree direction is parallel, and to be stained with more than or equal to two width be 4mm at intervals of 2mm strip one side adhesive tape, then by substrate along vertically long Bar shaped one side adhesive tape direction is cut, and is cut medicine block columns on the rectangle substrate to get off and is more than or equal to two row, by pasting twice The test strips that final production goes out matrix form distribution are cut three times;During from branch injecting glue mounting method technique productions, according to test paper The quantity of medicine block on bar, prepare the rectangle of identical quantity or coiled original paper, original paper is immersed respectively different Dried after reagent, all original papers cut into the strip body paper of 4mm width after drying, and liquid glue point is used on rectangle substrate Glue device points out the glue point of matrix form distribution, and the transversely arranged line number of glue point is more than or equal to 2, and vertically disposed columns is more than or waited In 2, different reagent strip body paper will be soaked with and cut into the blockage of 4mm length while be pasted onto in glue point, then substrate is cut out Cut, cut the line number of medicine block and columns on the rectangle substrate to get off and be more than or equal to 2, pass through branch injecting glue mounting method final production Go out the test strips of matrix form distribution.
Because the distribution of medicine block matrix form changes test strips structure, the substrate of test strips, which broadens, to shorten, and medicine block concentrates on one Rise and be easy to immersion liquid, it is easy to use, test strips analyzer is used fixed figure because the medicine block of test strips concentrates in together As acquisition method, the testing agency of test strips analyzer, the fixed IMAQ knot of test strips analyzer greatly simplify Structure by detection platform, the surface for the medicine block for being arranged on the distribution of test strips matrix form a CCD camera and be distributed on CCD and take the photograph As the luminous tubes composition of two of head surrounding or more than three, CCD camera and luminous tube may be mounted at same camera On circuit board, during detection, the test strips by immersion liquid are placed in detection platform, and tester clicks button, main circuit board hair Go out all pieces of medicines that instruction makes luminous tube illuminate matrix form distribution, CCD camera exists all medicine blocks shooting that matrix form is distributed On one pictures, then picture is passed into main circuit board the graphics field of each medicine block on picture carried out with image analysis software Color analysis, the discoloration data of each medicine block are drawn, the content of special component corresponding to each piece of medicine block are drawn by computing, Display is supplied to tester to be applied as judgment basis, this fixed IMAQ structure of test strips over the display In small-sized household hand-held test strips analyzer, fixed IMAQ structure is fixed on small-sized household hand-held test strips point On the upper casing of analyzer, the lower casing of detection platform and small-sized household hand-held test strips analyzer is set to integral, this test paper The fixed IMAQ structure of bar can also be applied in semi-automatic test strips analyzer and full-automatic test strips analyzer, work as examination When the fixed IMAQ structure of paper slip is applied in specific test strips analyzer, in the fixed IMAQ structure of test strips Detection platform will be integral with the apparatus structure element fusion of these test strips analyzers.
Brief description of the drawings
Fig. 1 is the present invention a kind of test strips and the production technology of test strips and the embodiment of detection method of matrix form distribution Test strips structure schematic diagram;
Fig. 2 is the present invention a kind of test strips and the production technology of test strips and the embodiment of detection method of matrix form distribution The fixed IMAQ structural representation of test strips;
Fig. 3 is the present invention a kind of test strips and the production technology of test strips and the embodiment of detection method of matrix form distribution Small-sized household hand-held test strips analyzer schematic diagram;
Fig. 4 is the present invention a kind of test strips and the production technology of test strips and the embodiment of detection method of matrix form distribution Small-sized household hand-held test strips analyzer split structural representation;
Marked in figure:1st, the test strips of matrix form distribution, 1-1, substrate, 1-2, medicine block, 2, CCD camera, 3, luminous tube, 4th, camera circuit board, 5, detection platform, 6, small-sized household hand-held test strips analyzer, 6-1, upper casing, 6-2, display, 6- 3rd, lower casing, 6-4, button, 6-5, main circuit board.
Embodiment
A kind of test strips of matrix form distribution of the present invention and the production technology and detection method of test strips implement such as Fig. 1 institutes Show, the substrate 1-1 of test strips 1 shape is rectangle, and length-width ratio is less than or equal to 4 times, and medicine block 1-2 is arranged with a matrix type On substrate 1-1, transversely arranged line number is more than or equal to 2, and vertically disposed columns is more than or equal to 2, in every row or each column The medicine block 1-2 quantity of upper arrangement is more than or equal to 2, and medicine block 1-2's is shaped as regular polygon rectangle either circle, The length of side or the length of radius are 1-10mm, and between medicine block 1-2 row and row, the spacing that arranges between the column and the column is between 1-5mm; With the change of the shape of test strips 1, the production technology of test strips 1 has two kinds of selectable methods, be respectively twice paste, three Secondary trimming processes and branch injecting glue mounting method;From twice paste, three times cutting process produce when, according to the medicine block in test strips 1 1-2 quantity, prepare the original paper of the rectangle of identical quantity, dried after different reagents is immersed to original paper respectively, The double faced adhesive tape of formed objects is stained with one face of each body paper, all original papers for being stained with double faced adhesive tape are cut into The strip body paper of 4mm width, the template of a formed objects in the paper pressure without glue of rectangle one side gummed paper, put down in template Row is provided with strip holes of multiple a width of 4mm at intervals of 2mm, will cut into the wide strip body paper glue surfaces of 4mm towards one side glue letterweight Enter into the strip hole of template, remove template, it is parallel from side on rectangle one side gummed paper to be stained with a plurality of width for being soaked with different reagents Be 4mm cuts into the wide strip one sides of 4mm at intervals of 2mm strip body paper, then by one side gummed paper along vertical sliver body paper direction Adhesive tape, presses a size identical template along its length on rectangle substrate 1-1, parallel along its length in template to be provided with Multiple a width of 4mm will cut into the wide strip one side adhesive tape glue surfaces of 4mm and be pressed into towards substrate 1-1 at intervals of 2mm strip hole In the strip hole of template, remove template, it is parallel along its length on rectangle substrate 1-1 to be stained with more than or equal to two width and be 4mm is cut at intervals of 2mm strip one side adhesive tape, then by substrate along vertically long bar shaped one side glue bar direction, cuts the square to get off Medicine block 1-2 columns is more than or equal to two row on shape substrate 1-1, goes out matrix form point by pasting and cutting three times final production twice The test strips 1 of cloth;During from branch injecting glue mounting method technique productions, according to the quantity of the medicine block 1-2 in test strips 1, prepare phase Rectangle or coiled original paper with quantity, dried after different reagents is immersed to original paper respectively, all originals after drying Paper paper cutting points out what matrix form was distributed on rectangle substrate 1-1 into the strip body paper of 4mm width with liquid glue adhesive dispensing device Glue point, the transversely arranged line number of glue point are more than or equal to 2, and vertically disposed columns is more than or equal to 2, will be soaked with different reagent length Bar shaped body paper cuts into the blockage of 4mm length while is pasted onto in glue point, then substrate 1-1 is cut, and cuts the rectangle to get off Medicine block 1-2 line number and columns are more than or equal to 2 on substrate 1-1, go out matrix form point by branch injecting glue mounting method final production The test strips 1 of cloth.
As shown in Figure 2, Figure 3, Figure 4, because the distribution of medicine block 1-2 matrix forms makes the structural change of test strips 1, the base of test strips 1 Piece 1-1, which broadens, to shorten, and medicine block 1-2, which is concentrated in together, is easy to immersion liquid, easy to use, because the medicine block 1-2 of test strips 1 concentrates on one Rising allows test strips analyzer to use fixed image-pickup method, greatly simplify the detection machine of test strips analyzer Structure, the fixed IMAQ structure of test strips analyzer by detection platform 5, be arranged on the medicine block of the matrix form of test strips 1 distribution One CCD camera 2 of 1-2 surface and 3 groups of the luminous tube of two or more than three for being distributed on the surrounding of CCD camera 2 Into, CCD camera 2 and luminous tube 3 may be mounted on same camera circuit board 4, during detection, the test strips by immersion liquid 1 is placed in detection platform 5, and tester clicks button 6-4, and main circuit board 6-5, which sends instruction, makes luminous tube 3 illuminate matrix form All pieces of medicine 1-2 of distribution, all medicine block 1-2 that matrix form is distributed by CCD camera 2 are shot on a pictures, then will figure Piece passes to main circuit board 6-5 and carries out color analysis to the graphics field of each medicine block 1-2 on picture with image analysis software, obtains Go out each medicine block 1-2 discoloration data, the content of special component corresponding to each piece of medicine block 1-2 is drawn by computing, show It is supplied to tester to be applied as judgment basis, this fixed IMAQ structure of test strips on display 6-2 In small-sized household hand-held test strips analyzer 6, fixed IMAQ structure is fixed on small-sized household hand-held test strips On the upper casing 6-1 of analyzer 6, the lower casing 6-3 of detection platform 5 and small-sized household hand-held test strips analyzer 6 is arranged to one Body, this fixed IMAQ structure of test strips can also be applied in semi-automatic test strips analyzer and full-automatic test strips point In analyzer, when the fixed IMAQ structure of test strips is applied in specific test strips analyzer, the fixed figure of test strips As the detection platform 5 in collection structure will be integral with the apparatus structure element fusion of these test strips analyzers.

Claims (4)

1. a kind of test strips of matrix form distribution and the production technology and detection method of test strips is characterized in that:
The shape of the substrate (1-1) of described test strips (1) is rectangle, and length-width ratio is less than or equal to 4 times, medicine block (1-2) with The form of matrix is arranged on substrate (1-1), and transversely arranged line number is more than or equal to 2, and vertically disposed columns is more than or waited In 2, medicine block (1-2) quantity arranged on every row or each column is more than or equal to 2, medicine block (1-2) be shaped as regular polygon or Person is that rectangle is either circular, and the length of the length of side or radius is 1-10mm, between the row and row of medicine block (1-2), is arranged and row Between the spacing that arranges between 1-5mm.
2. a kind of test strips of matrix form distribution according to claim 1 and the production technology and detection method of test strips, It is characterized in that:
When described stickup twice, three times cutting process produce, according to the quantity of the medicine block (1-2) in test strips (1), prepare phase With the original paper of the rectangle of quantity, dried after different reagents is immersed to original paper respectively, the one of each body paper The double faced adhesive tape of formed objects is stained with individual face, all original papers for being stained with double faced adhesive tape are cut into the strip body paper of 4mm width, The template of a formed objects in the paper pressure without glue of rectangle one side gummed paper, it is parallel in template to be provided with multiple a width of 4mm At intervals of 2mm strip hole, the wide strip body paper glue surfaces of 4mm will be cut into towards one side glue paper and are pressed into the strip hole of template In, remove template, it is parallel from side on rectangle one side gummed paper to be stained with a plurality of width for being soaked with different reagents and grown for 4mm at intervals of 2mm Bar body paper, then one side gummed paper is cut into the wide strip one side adhesive tape of 4mm along vertical sliver body paper direction, in rectangle substrate Press a size identical template on (1-1) along its length, it is parallel along its length in template to be provided with multiple a width of 4mm intervals For 2mm strip hole, the wide strip one side adhesive tape glue surfaces of 4mm will be cut into towards substrate (1-1) and are pressed into the strip hole of template In, remove template, parallel along its length on rectangle substrate (1-1) to be stained with more than or equal to two width be 4mm at intervals of 2mm Strip one side adhesive tape, then substrate is cut along vertically long bar shaped one side glue bar direction, cut on the rectangle substrate (1-1) to get off Medicine block (1-2) columns is more than or equal to two row, the test paper for going out matrix form by pasting and cutting three times final production twice and being distributed Bar 1.
3. a kind of test strips of matrix form distribution according to claim 1 and the production technology and detection method of test strips, It is characterized in that:
During described branch injecting glue mounting method technique productions, according to the quantity of the medicine block (1-2) in test strips (1), prepare identical The rectangle of quantity or coiled original paper, dried after different reagents is immersed to original paper respectively, all body paper after drying Paper cutting growth bar shaped body paper, the glue point of matrix form distribution, glue point are pointed out with liquid glue adhesive dispensing device on rectangle substrate (1-1) Transversely arranged line number is more than or equal to 2, and vertically disposed columns is more than or equal to 2, will be soaked with different reagent strip body paper Cut into blockage while be pasted onto in glue point, then substrate (1-1) is cut, cut medicine block on the rectangle substrate (1-1) to get off The line number and columns of (1-2) are more than or equal to 2, and the test strips 1 of matrix form distribution are gone out by branch injecting glue mounting method final production.
4. a kind of test strips of matrix form distribution according to claim 1 and the production technology and detection method of test strips, It is characterized in that:
Described test strips analyzer can use fixed image-pickup method, and fixed IMAQ structure is by detection platform (5), it is arranged on a CCD camera (2) of the surface of the medicine block (1-2) of test strips (1) matrix form distribution and is distributed on CCD The composition of the luminous tube (3) of two or more than three of camera (2) surrounding, CCD camera (2) and luminous tube (3) can be installed On same camera circuit board (4), during detection, the test strips (1) by immersion liquid are placed in detection platform (5), are tested Person clicks button (6-4), and main circuit board (6-5) sends all pieces of medicine (1- that instruction makes luminous tube (3) illuminate matrix form distribution 2), all medicine blocks (1-2) that matrix form is distributed are shot and pass to main circuit on a pictures, then by picture by CCD camera (2) Plate (6-5) carries out color analysis with image analysis software to the graphics field of each medicine block (1-2) on picture, draws each The discoloration data of medicine block (1-2), the content of special component corresponding to each piece of medicine block (1-2) is drawn by computing, is shown in aobvious Show and be supplied to tester to be applied small as judgment basis, this fixed IMAQ structure of test strips on device (6-2) In type Household handheld test strips analyzer (6), fixed IMAQ structure is fixed on small-sized household hand-held test strips On the upper casing (6-1) of analyzer (6), by detection platform (5) and the lower casing (6- of small-sized household hand-held test strips analyzer (6) 3) set it is integral, this fixed IMAQ structure of test strips can also apply semi-automatic test strips analyzer and it is complete from In dynamic test strips analyzer, when the fixed IMAQ structure of test strips is applied in specific test strips analyzer, test paper Detection platform (5) in the fixed IMAQ structure of bar will with the apparatus structure element fusions of these test strips analyzers into One.
CN201610523190.4A 2016-06-28 2016-06-28 A kind of test strips of matrix form distribution and the production technology and detection method of test strips Pending CN107543815A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109142339A (en) * 2018-07-21 2019-01-04 贾晓轻 The detection kit and application method
CN112362648A (en) * 2020-10-30 2021-02-12 厦门波耐模型设计有限责任公司 Integrated test paper and preparation process thereof
WO2022088567A1 (en) * 2020-10-30 2022-05-05 厦门波耐模型设计有限责任公司 Integrated test paper-based detection method and apparatus, and production process therefor

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109142339A (en) * 2018-07-21 2019-01-04 贾晓轻 The detection kit and application method
CN112362648A (en) * 2020-10-30 2021-02-12 厦门波耐模型设计有限责任公司 Integrated test paper and preparation process thereof
CN112362648B (en) * 2020-10-30 2021-11-26 厦门波耐模型设计有限责任公司 Integrated test paper and preparation process thereof
WO2022088567A1 (en) * 2020-10-30 2022-05-05 厦门波耐模型设计有限责任公司 Integrated test paper-based detection method and apparatus, and production process therefor

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Application publication date: 20180105