CN107515131A - A kind of preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab - Google Patents
A kind of preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab Download PDFInfo
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- CN107515131A CN107515131A CN201710626731.0A CN201710626731A CN107515131A CN 107515131 A CN107515131 A CN 107515131A CN 201710626731 A CN201710626731 A CN 201710626731A CN 107515131 A CN107515131 A CN 107515131A
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- cotton swab
- nano silver
- high efficiency
- biological material
- preparation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N2001/028—Sampling from a surface, swabbing, vaporising
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
The invention discloses a kind of preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab, most microorganisms can be killed using Nano Silver, and do not produce drug resistance, itself is lossless, no matter the characteristic of bactericidal action is had in solid state or suspension state, it is hydrophilic based surfactants using lauryl sodium sulfate, the biological evidences such as cast-off cells can be eluted characteristic from carrier, antibacterial agent and surfactant are added in cotton swab fiber, so as to reach biological evidence degradation problem caused by control is acted on due to microbial spoilage and improve the purpose of biological evidence recovery rate.
Description
Technical field
The present invention relates to a kind of preparation method of extracting tool, more particularly to a kind of anti-degradation biological material evidence high efficiency extraction cotton
The preparation method of label.
Background technology
Existing biological evidence extraction cotton swab has been only prevented from " people source " pollution, and can not overcome the degraded of biological evidence
Problem, generally degrade after extraction, be just difficult to detect after 48 hours；And recovery rate is not high, experiments verify that,
To the cell extraction rate of the micro biological evidence including cast-off cells less than 50%.
The content of the invention
To solve the above problems, the present invention provides a kind of preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab, profit
Most microorganisms can be killed with Nano Silver, and do not produce drug resistance, itself is lossless, no matter in solid state or is suspended
Liquid status have the characteristic of bactericidal action, are hydrophilic based surfactants using lauryl sodium sulfate, can be by cast-off cells etc.
Biological evidence elutes characteristic from carrier, and antibacterial agent and surfactant are added in cotton swab fiber, so as to reach
Control biological evidence degradation problem caused by being acted on due to microbial spoilage and improve the purpose of biological evidence recovery rate.
To achieve the above object, the present invention uses following technological means：
The present invention provides a kind of preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab, it is characterised in that including with
Lower step：
(1) lauryl sodium sulfate that the Nano Silver suspension and concentration that compound concentration is 1%~10% are 5%~15%
Solution；
(2) Nano Silver suspension, the sodium dodecyl sulfate solution configured step (1), by Nano Silver suspension and ten
The ratio of sodium dialkyl sulfate solution is 10：1~20：The new mixed liquor of 1 configuration；
(3) the new mixed liquor for taking 10~50 microlitres of steps (2) to obtain instils in pollution-free cotton swab head；
(4) by after the cotton swab row drying process in step (3), independent packaging.
Further, the Nano Silver suspension concentration in step (1) is 1%, and the concentration of sodium dodecyl sulfate solution is
5%.
Further, the Nano Silver suspension concentration in step (1) is 5%, and the concentration of sodium dodecyl sulfate solution is
10%.
Further, the Nano Silver suspension concentration in step (1) is 10%, and the concentration of sodium dodecyl sulfate solution is
15%.
Further, the ratio of Nano Silver suspension and sodium dodecyl sulfate solution is 10 in step (2)：1.
Further, the ratio of Nano Silver suspension and sodium dodecyl sulfate solution is 15 in step (2)：1.
Further, the ratio of Nano Silver suspension and sodium dodecyl sulfate solution is 20 in step (2)：1.
Beneficial effects of the present invention：
The present invention can kill most microorganisms using Nano Silver, and not produce drug resistance, and itself is lossless, no matter
Solid state or suspension state have the characteristic of bactericidal action, are hydrophilic group surface-active using lauryl sodium sulfate
Agent, the biological evidences such as cast-off cells can be eluted characteristic from carrier, antibacterial agent and surfactant are added to cotton
Sign in fiber, so as to reach biological evidence degradation problem caused by control is acted on due to microbial spoilage and improve biological evidence
The purpose of recovery rate.
Brief description of the drawings
Fig. 1 is the structural representation of the present invention；
Embodiment
Below in conjunction with the accompanying drawings and specific embodiment the present invention will be further described.
Embodiment 1：As shown in figure 1, the present embodiment provides a kind of anti-degradation biological material evidence high efficiency extraction cotton swab, including cotton swab
Bar 1, the head of cotton swab bar 1 are provided with cotton swab fiber 2, antiseptic and surfactant 3 are provided with cotton swab fiber 2, specific to make
Method is as follows：
(1) sodium dodecyl sulfate solution that the Nano Silver suspension and concentration that compound concentration is 1% are 5%；
(2) Nano Silver suspension, the sodium dodecyl sulfate solution configured step (1), by Nano Silver suspension and ten
The ratio of sodium dialkyl sulfate solution is 10：The new mixed liquor of 1 configuration；
(3) the new mixed liquor for taking 10 microlitres of steps (2) to obtain instils in pollution-free cotton swab head；
(4) by after the cotton swab row drying process in step (3), independent packaging.
Nano Silver can kill most microorganisms, and not produce drug resistance, and itself is lossless, no matter in solid state also
It is that suspension state has bactericidal action.Lauryl sodium sulfate is hydrophilic based surfactants, can be by biologies such as cast-off cells
Material evidence elutes from carrier, then is adsorbed on cotton swab fiber, can improve extraction efficiency.
Embodiment 2：As shown in figure 1, the present embodiment provides a kind of anti-degradation biological material evidence high efficiency extraction cotton swab, including cotton swab
Bar 1, the head of cotton swab bar 1 are provided with cotton swab fiber 2, antiseptic and surfactant 3 are provided with cotton swab fiber 2, specific to make
Method is as follows：
(1) sodium dodecyl sulfate solution that the Nano Silver suspension and concentration that compound concentration is 5% are 10%；
(2) Nano Silver suspension, the sodium dodecyl sulfate solution configured step (1), by Nano Silver suspension and ten
The ratio of sodium dialkyl sulfate solution is 15：The new mixed liquor of 1 configuration；
(3) the new mixed liquor for taking 30 microlitres of steps (2) to obtain instils in pollution-free cotton swab head；
(4) by after the cotton swab row drying process in step (3), independent packaging.
Nano Silver can kill most microorganisms, and not produce drug resistance, and itself is lossless, no matter in solid state also
It is that suspension state has bactericidal action.Lauryl sodium sulfate is hydrophilic based surfactants, can be by biologies such as cast-off cells
Material evidence elutes from carrier, then is adsorbed on cotton swab fiber, can improve extraction efficiency.
Embodiment 3：As shown in figure 1, the present embodiment provides a kind of anti-degradation biological material evidence high efficiency extraction cotton swab, including cotton swab
Bar 1, the head of cotton swab bar 1 are provided with cotton swab fiber 2, antiseptic and surfactant 3 are provided with cotton swab fiber 2, specific to make
Method is as follows：
(1) sodium dodecyl sulfate solution that the Nano Silver suspension and concentration that compound concentration is 10% are 15%；
(2) Nano Silver suspension, the sodium dodecyl sulfate solution configured step (1), by Nano Silver suspension and ten
The ratio of sodium dialkyl sulfate solution is 20：The new mixed liquor of 1 configuration；
(3) the new mixed liquor for taking 50 microlitres of steps (2) to obtain instils in pollution-free cotton swab head；
(4) by after the cotton swab row drying process in step (3), independent packaging.
Nano Silver can kill most microorganisms, and not produce drug resistance, and itself is lossless, no matter in solid state also
It is that suspension state has bactericidal action.Lauryl sodium sulfate is hydrophilic based surfactants, can be by biologies such as cast-off cells
Material evidence elutes from carrier, then is adsorbed on cotton swab fiber, can improve extraction efficiency.
Claims (8)
1. a kind of preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab, it is characterised in that comprise the following steps：
(1) lauryl sodium sulfate that the Nano Silver suspension and concentration that compound concentration is 1%~10% are 5%~15% is molten
Liquid；
(2) Nano Silver suspension, the sodium dodecyl sulfate solution configured step (1), by Nano Silver suspension and dodecane
The ratio of base metabisulfite solution is 10：1~20：The new mixed liquor of 1 configuration；
(3) the new mixed liquor for taking 10~50 microlitres of steps (2) to obtain instils in pollution-free cotton swab head；
(4) by after the cotton swab row drying process in step (3), independent packaging.
A kind of 2. preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab according to right wants 1, it is characterised in that step
Suddenly the Nano Silver suspension concentration in (1) is 1%, and the concentration of sodium dodecyl sulfate solution is 5%.
A kind of 3. preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab according to right wants 1, it is characterised in that step
Suddenly the Nano Silver suspension concentration in (1) is 5%, and the concentration of sodium dodecyl sulfate solution is 10%.
A kind of 4. preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab according to right wants 1, it is characterised in that step
Suddenly the Nano Silver suspension concentration in (1) is 10%, and the concentration of sodium dodecyl sulfate solution is 15%.
A kind of 5. preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab according to right wants 1, it is characterised in that step
Suddenly the ratio of Nano Silver suspension and sodium dodecyl sulfate solution is 10 in (2)：1.
A kind of 6. preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab according to right wants 1, it is characterised in that step
Suddenly the ratio of Nano Silver suspension and sodium dodecyl sulfate solution is 15 in (2)：1.
A kind of 7. preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab according to right wants 1, it is characterised in that step
Suddenly the ratio of Nano Silver suspension and sodium dodecyl sulfate solution is 20 in (2)：1.
8. a kind of anti-degradation biological material evidence high efficiency extraction cotton swab, it is characterised in that the method described in usage right requirement 1 makes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710626731.0A CN107515131A (en) | 2017-07-28 | 2017-07-28 | A kind of preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710626731.0A CN107515131A (en) | 2017-07-28 | 2017-07-28 | A kind of preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab |
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| CN107515131A true CN107515131A (en) | 2017-12-26 |
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| CN201710626731.0A Pending CN107515131A (en) | 2017-07-28 | 2017-07-28 | A kind of preparation method of anti-degradation biological material evidence high efficiency extraction cotton swab |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109363728A (en) * | 2018-09-27 | 2019-02-22 | 广州维帝医疗技术有限公司 | Buccal swab and its preparation method and application, acquisition and the method for saving saliva DNA |
Citations (7)
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|---|---|---|---|---|
| CN1943593A (en) * | 2006-11-03 | 2007-04-11 | 段炬红 | External use anti-bacteria foaming agent for gynecology |
| CN101485331A (en) * | 2009-02-27 | 2009-07-22 | 深圳清华大学研究院 | Nano silver disinfectant |
| CN102181434A (en) * | 2009-08-05 | 2011-09-14 | 公安部物证鉴定中心 | Method for extracting purified DNA from human exfoliative cells |
| CN202235379U (en) * | 2011-08-18 | 2012-05-30 | 洛阳奥力诺生物科技有限公司 | Biological spot draws cotton swab suit |
| CN103598212A (en) * | 2013-10-15 | 2014-02-26 | 青岛叁鼎卫生制品有限公司 | Biologically extracted disinfectant |
| CN103900844A (en) * | 2013-12-31 | 2014-07-02 | 常州市公安局 | Field biological physical evidence extraction cotton swab |
| CN103926103A (en) * | 2013-01-16 | 2014-07-16 | 裴军昌 | Extraction cotton swab special for biological evidence |
-
2017
- 2017-07-28 CN CN201710626731.0A patent/CN107515131A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1943593A (en) * | 2006-11-03 | 2007-04-11 | 段炬红 | External use anti-bacteria foaming agent for gynecology |
| CN100396290C (en) * | 2006-11-03 | 2008-06-25 | 段炬红 | External use anti-bacteria foaming agent for gynecology |
| CN101485331A (en) * | 2009-02-27 | 2009-07-22 | 深圳清华大学研究院 | Nano silver disinfectant |
| CN102181434A (en) * | 2009-08-05 | 2011-09-14 | 公安部物证鉴定中心 | Method for extracting purified DNA from human exfoliative cells |
| CN202235379U (en) * | 2011-08-18 | 2012-05-30 | 洛阳奥力诺生物科技有限公司 | Biological spot draws cotton swab suit |
| CN103926103A (en) * | 2013-01-16 | 2014-07-16 | 裴军昌 | Extraction cotton swab special for biological evidence |
| CN103598212A (en) * | 2013-10-15 | 2014-02-26 | 青岛叁鼎卫生制品有限公司 | Biologically extracted disinfectant |
| CN103900844A (en) * | 2013-12-31 | 2014-07-02 | 常州市公安局 | Field biological physical evidence extraction cotton swab |
Non-Patent Citations (1)
| Title |
|---|
| 钱培芬等主编: "《静脉输液置管与维护指南》", 31 October 2008, 世界图书上海出版公司 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109363728A (en) * | 2018-09-27 | 2019-02-22 | 广州维帝医疗技术有限公司 | Buccal swab and its preparation method and application, acquisition and the method for saving saliva DNA |
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Application publication date: 20171226 |
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| RJ01 | Rejection of invention patent application after publication |