CN107510055A - A kind of food therapeutic composition for female health and preparation method thereof - Google Patents
A kind of food therapeutic composition for female health and preparation method thereof Download PDFInfo
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- 238000002360 preparation method Methods 0.000 title claims description 12
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- 238000011835 investigation Methods 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 210000005075 mammary gland Anatomy 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
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- 238000005457 optimization Methods 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
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- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
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- 230000001737 promoting effect Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 229930002330 retinoic acid Natural products 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 229910052701 rubidium Inorganic materials 0.000 description 1
- IGLNJRXAVVLDKE-UHFFFAOYSA-N rubidium atom Chemical compound [Rb] IGLNJRXAVVLDKE-UHFFFAOYSA-N 0.000 description 1
- 108010048734 sclerotin Proteins 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical compound C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 description 1
- 235000021286 stilbenes Nutrition 0.000 description 1
- 229910052712 strontium Inorganic materials 0.000 description 1
- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 1
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- 229960001727 tretinoin Drugs 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Botany (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of food therapeutic composition for female health, it is made up of each component of following parts by weight:25~35 parts of maca, 18~22 parts of line leaf broom top, 13~15 parts of natto, 15~18 parts of the Radix Astragali, 8~12 parts of Semen Cuscutae, 7~10 parts of Fructus Corni, 5~8 parts of radix cyathulae, 5~10 parts of Ligusticum wallichii, 10~15 parts of the rhizome of davallia, 6~9 parts of raspberry, 6~9 parts of calcium fruit.The food therapeutic composition for female health has regulation estrogen, prevent the effects such as bone amount is reduced and bone structure changes, with multiple functions such as regulation internal system, strengthen immunity, nourishing liver and kidney, controlling nocturnal emission with astringent drugs of enriching blood, beautifying face and moistering lotions, Nantural non-toxic side effect, it is adapted to long-term consumption.
Description
Technical field
The invention belongs to health product technology field, more particularly, to a kind of food therapeutic composition for female health and
Its preparation method.
Background technology
With the increasingly quickening of rhythm of life so that disease also increasingly increases as caused by habits and customs and environmental factor.
Modern female is due to the dual-pressure born family, worked, and nerve is in tension, and mood change is abnormal, and this can cause to swash
The disorder of element secretion, causes endocrinopathy, causes the generation of a variety of diseases.Estrogen can keep the content of calcium in bone, protect
The flintiness of bone is held, when female estrogen parasecretion, can frequently result in the loss of sclerotin, using soreness of waist and knee as main table
It is existing.Further, since modern female focuses on stature, lost weight frequently with the mode kept on a diet, and this will likely turn into
The fuse cord of osteoporosis and fracture occurs in the future.External a investigation to thousands of names women of more than 30 years old, find wherein
82% women has begun to osteoporosis to a certain degree occur, or the danger of existing osteoporosis.This is due to them
Usually partial eclipse vegetarian diet, nutrition arrangement is unreasonable, causes to take the photograph hypocalcia in vivo;On the other hand, because fat and estrogen content have
Close, female estrogen tends to vary with fat and reduces and reduce, and estrogen level declines for a long time, can accelerate the calcareous loss of bone.
Maca (Lepedium meyenii Walp), originate in Peru's andes region of more than 4000 meters of height above sea level, category ten
Zi Hua sections separate row Vegetable spp.Maca is a kind of medical and edible dual purpose plant, and edible portion is its root.Maca is nutritious, in dry root
Containing more than 10% protein, 8.5% fiber, its include abundant zinc, calcium, iron, titanium, rubidium, potassium, sodium, copper, manganese, magnesium,
The mineral matters such as strontium, phosphorus, iodine, and containing vitamin C, B1, B2, B6, A, E, B12, B5, fat is mostly unrighted acid, sub- oil
Sour and linolenic content reaches more than the 53% of fat content, active skull cap components include dilute macamide, maca, alkaloid,
Polysaccharide, glucosinolate and its catabolite benzyl isothiocyanate, sterol, polyphenols, being can be with the new of prevention of various diseases
Resource food.
It is, therefore, desirable to provide the maca food therapeutic composition of a kind of optimization of C/C composites and preparation method, for female health, and
Women osteoporosis is prevented and treated to a certain extent.
The content of the invention
For above-mentioned the problems of the prior art, the invention provides the food therapeutic composition for female health.
Another object of the present invention is to provide the preparation method of above-mentioned food therapeutic composition.
The above-mentioned purpose of the present invention is achieved by the following technical programs.
A kind of food therapeutic composition for female health, it is made up of each component of following parts by weight:25~35 parts of maca,
18~22 parts of line leaf broom top, 13~15 parts of natto, 15~18 parts of the Radix Astragali, 8~12 parts of Semen Cuscutae, 7~10 parts of Fructus Corni, river ox
5~8 parts of knee, 5~10 parts of Ligusticum wallichii, 10~15 parts of the rhizome of davallia, 6~9 parts of raspberry, 6~9 parts of calcium fruit.
The present invention optimizes above-mentioned formulation ratio, not only has certain pre- anti-osteoporosis, arthritic work(to women
Imitate, also have regulation internal system, strengthen immunity, nourishing liver and kidney, controlling nocturnal emission with astringent drugs of enriching blood, the neutralization of official report gas, benefit Yang and benefiting Yin etc. a variety of
Function.Food therapeutic composition of the present invention has abundant nutritional ingredient and mineral matter needed by human, vitamin, can improve estrogen
Expression of receptor and skeletonization key factor bone morphogenetic protein 2, Core-binding factorα1, the table of type i collagen and alkaline phosphatase
Reach, promoting bone growing process;Estrogen level caused by antagonism retinoic acid reduces and anti-tartrate phosphatase activity rises, suppression
Bone information process processed, finally plays function of resisting osteoporosis.
Said components raw material of the present invention is the active component of plant, including root, stem, leaf, flower and/or fruit, or its extraction
Thing.
Preferably, the maca includes maca root and maca leaf, and the ratio of weight and number of the maca root and maca leaf is 1:
1.5。
Maca root and maca leaf are coordinated, contained in the vitamin C and mineral calcium and Ma Kagen that are rich in maca leaf
Protein, fiber, the mixture of several mineral materials, vitamin and active skull cap components, be advantageous to further to improve anti-oxidant, pre-
The effect of preventing bone rarefaction.
Preferably, it is made up of each component of following parts by weight:32 parts of maca, 18 parts of line leaf broom top, 14 parts of natto, Huang
16 parts of stilbene, 10 parts of Semen Cuscutae, 9 parts of Fructus Corni, 6 parts of radix cyathulae, 8 parts of Ligusticum wallichii, 12 parts of the rhizome of davallia, 8 parts of raspberry, 7 parts of calcium fruit.
The preparation method of the described food therapeutic composition for female health, comprises the following steps:
S1. maca being divided into maca root and maca leaf two parts, the maca root is crushed to 5~25 mesh and extracted, 60~
95% ethanol water extracts, and in solid-liquid ratio, 1: 10~1: 15,65~80 DEG C extract 2~4 times, and 2~3h, macamide are total every time
Content 6~15%, it is concentrated and dried, extractum A must be obtained;
S2. line leaf broom top, the Radix Astragali, Semen Cuscutae, Fructus Corni, radix cyathulae, Ligusticum wallichii, Drynaria rhizome powder are broken to 5~25 mesh, mixed
Close and add 10~45% ethanol waters, 1: 10~1: 15,65~90 DEG C are extracted 2~4 times in solid-liquid ratio, and 1~5h, is concentrated every time
Dry, obtain medicinal extract B;
S3. the maca leaf uses growth period cauline leaf, and the natto uses 80~120 mesh natto powders, by the maca leaf
Mixed with raspberry, calcium fruit, dry, pulverize to 80~120 mesh, be well mixed with natto powder, extractum A and B, homogeneous, obtained described
Food therapeutic composition.
After obtaining the maca composition as stated above, granule, pulvis can be prepared into using existing process, is dissipated
Any one in agent, tablet, pill or capsule.
Preferably, solid-liquid ratio described in step S1 is 1:12.5, the ethanol water concentration is 70~75%.
Preferably, solid-liquid ratio described in step S2 is 1:12.5, the ethanol water concentration is 25~30%.
Compared with prior art, beneficial effect of the present invention is:The food therapeutic composition for female health is for female
Property have regulation estrogen, prevention bone amount reduce and bone structure change etc. effect.Optimize matching somebody with somebody when for the food therapeutic composition
Preparation method, there are effectively a variety of work(such as regulation internal system, strengthen immunity, nourishing liver and kidney, controlling nocturnal emission with astringent drugs of enriching blood, beautifying face and moistering lotion
Can, Nantural non-toxic side effect, it is adapted to long-term consumption.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.Unless stated otherwise, the reagent of the invention used, method and apparatus is the art conventional reagent, methods
And equipment.
It is as a kind of more preferably embodiment, preparation method of food therapeutic composition of the present invention:
S1. maca being divided into maca root and maca leaf two parts, the maca root is crushed to 5~25 mesh and extracted, 60~
95% ethanol water extracts, and in solid-liquid ratio, 1: 10~1: 15,65~80 DEG C extract 2~4 times, and 2~3h, macamide are total every time
Content 6~15%, it is concentrated and dried, extractum A must be obtained;
S2. line leaf broom top, the Radix Astragali, Semen Cuscutae, Fructus Corni, radix cyathulae, Ligusticum wallichii, Drynaria rhizome powder are broken to 5~25 mesh, mixed
Close and add 10~45% ethanol waters, 1: 10~1: 15,65~90 DEG C are extracted 2~4 times in solid-liquid ratio, and 1~5h, is concentrated every time
Dry, obtain medicinal extract B;
S3. the maca leaf uses growth period cauline leaf, and the natto uses 80~120 mesh natto powders, by the maca leaf
Mixed with raspberry, calcium fruit, dry, pulverize to 80~120 mesh, be well mixed with natto powder, extractum A and B, homogeneous, obtained described
Food therapeutic composition.
Found through lot of experiments, further optimum condition includes:Solid-liquid ratio described in step S1 is 1:12.5 institute
Ethanol water concentration is stated as 70~75%;Solid-liquid ratio described in step S2 is 1:12.5, the ethanol water concentration is 25
~30%.Following embodiments and comparative example prepare the food therapeutic composition according to most preferred preparation method.
The inventive method is further described by taking specific implementation condition as an example below.
Embodiment 1
A kind of food therapeutic composition for female health, it is made up of each component of following parts by weight:32 parts of maca, line leaf
18 parts of broom top, 14 parts of natto, 16 parts of the Radix Astragali, 10 parts of Semen Cuscutae, 9 parts of Fructus Corni, 6 parts of radix cyathulae, 8 parts of Ligusticum wallichii, the rhizome of davallia 12
Part, 8 parts of raspberry, 7 parts of calcium fruit.
In the maca, the ratio of weight and number of maca root and maca leaf is 1:1.5.
Embodiment 2
A kind of food therapeutic composition for female health, it is made up of each component of following parts by weight:25 parts of maca, line leaf
18 parts of broom top, 15 parts of natto, 18 parts of the Radix Astragali, 12 parts of Semen Cuscutae, 10 parts of Fructus Corni, 5 parts of radix cyathulae, 10 parts of Ligusticum wallichii, the rhizome of davallia
15 parts, 6 parts of raspberry, 6 parts of calcium fruit.
Other are same as Example 1.
Embodiment 3
A kind of food therapeutic composition for female health, it is made up of each component of following parts by weight:35 parts of maca, line leaf
22 parts of broom top, 13 parts of natto, 15 parts of the Radix Astragali, 8 parts of Semen Cuscutae, 7 parts of Fructus Corni, 8 parts of radix cyathulae, 5 parts of Ligusticum wallichii, the rhizome of davallia 10
Part, 9 parts of raspberry, 9 parts of calcium fruit.
Other are same as Example 1.
Embodiment 4
A kind of formula of food therapeutic composition for female health is same as Example 1, and difference is, the maca
Root and the ratio of weight and number of maca leaf are 2:1.
Other are same as Example 1.
Comparative example 1
A kind of food therapeutic composition for female health, substantially the same manner as Example 1, difference is, lack natto,
Raspberry, and 40 parts of maca, 32 parts of line leaf broom top.
Comparative example 2
A kind of food therapeutic composition for female health, substantially the same manner as Example 1, difference is, by the rhizome of davallia,
Calcium fruit is substituted for chondroitin sulfate, vitamine D3, and chondroitin sulfate is 12 parts, and vitamine D3 is 7 parts.
Application examples
(1) product made from the formula of embodiment 1~4 and comparative example 1~2 is subjected to zoopery.
60 12 month female SD rats are taken at random, are randomly divided into six groups, every group of average weight is substantially the same, and is raised respectively
The formulation product of embodiment 1~4 and comparative example 1~2 is fed, the feed of each group rat is identical, and ad lib.
Rat is continuously fed 12 weeks, 24 hours after last dose, puts to death, separates left femur, removes skin and flesh, measure left side
The bone density of neck of femur, femur midpoint and femur distal end.
Influence of the 1 different maca compositions of table to rat bone density
Compared with comparative example 1, * p < 0.05.
Data in each group experimental result and table are observed, more preferably embodiment is 1 to the present invention, and generally speaking, embodiment
Effect to be significantly better than comparative example, rat femur quality, calcium content of bone and femur midpoint bone density significantly increase in embodiment
Add, illustrate that the present invention has increase bone density for women osteoporosis and has preventive and therapeutic effect to osteoporosis.And change this hair
Bright formula (increasing or decreasing), the effect of all influenceing between each component and nutrition coordinate, and are unfavorable for playing optimum efficiency.
(2) food therapeutic composition for preparing the present invention, taken to clinical diagnosis for the women of endocrinopathy, daily 2
It is secondary, intake<5g, 3 courses for the treatment of of the medicine are taken, 10 days are a course for the treatment of.
Diagnostic criteria includes:Skin deteriorates, short-tempered, fat, tinnitus;Gynecological disease, breast disease, including dysmenorrhoea,
Irregular menstruation, swollen breasts, proliferation of mammary gland etc.;Dizzy weak, cold, trick is ice-cold, and complexion is dim, forgetful insomnia, and shortness of breath is lazy
Speech, slow in reacting, one's eyes are lustreless, and hair, skin lack gloss, pachylosis, and lip is powerless without pool, pale tongue, deficient and weak pulse.
Curative effect determinate standard:1. fully recover:Constitutional symptom is wholly absent, and continues more than two months not repeatedly.2. take a turn for the better:
Constitutional symptom substantially mitigates, and continues to mitigate to more than two months persons.It is 3. invalid:Constitutional symptom is without obvious alleviator.
Treatment results show, efficient up to more than 98%, and the food of comparative example 1~2 of the food therapeutic composition in embodiment
Composition is treated due to changing prescription of the present invention, its efficient obvious reduction, effective percentage is less than 85%.Illustrate dietotherapy of the present invention
Composition is compounded by the collaboration between each component, can significantly nurse one's health female incretion.
Implementation of the invention described in detail above, still, the present invention are not limited to specific thin in above-mentioned embodiment
Section, in the range of the technology design of the present invention, a variety of simple variants can be carried out to technical scheme, these simple changes
Type belongs to protection scope of the present invention.
Claims (6)
1. a kind of food therapeutic composition for female health, it is characterised in that be made up of each component of following parts by weight:Maca
25~35 parts, 18~22 parts of line leaf broom top, 13~15 parts of natto, 15~18 parts of the Radix Astragali, 8~12 parts of Semen Cuscutae, Fructus Corni 7~
10 parts, 5~8 parts of radix cyathulae, 5~10 parts of Ligusticum wallichii, 10~15 parts of the rhizome of davallia, 6~9 parts of raspberry, 6~9 parts of calcium fruit.
2. a kind of food therapeutic composition for female health according to claim 1, it is characterised in that the maca includes
The ratio of weight and number of maca root and maca leaf, the maca root and maca leaf is 1:1.5.
3. a kind of food therapeutic composition for female health according to claim 2, it is characterised in that by following parts by weight
Several each component compositions:32 parts of maca, 18 parts of line leaf broom top, 14 parts of natto, 16 parts of the Radix Astragali, 10 parts of Semen Cuscutae, Fructus Corni 9
Part, 6 parts of radix cyathulae, 8 parts of Ligusticum wallichii, 12 parts of the rhizome of davallia, 8 parts of raspberry, 7 parts of calcium fruit.
4. the preparation method of the food therapeutic composition for female health described in any one of claims 1 to 3, it is characterised in that
Comprise the following steps:
S1. maca is divided into maca root and maca leaf two parts, the maca root is crushed to the extraction of 5~25 mesh, 60~95% second
Alcohol solution extracts, and extracts 2~4 times in 1: 10~1: 15,65~80 DEG C of solid-liquid ratio, every time 2~3h, macamide total content 6
~15%, it is concentrated and dried, extractum A must be obtained;
S2. line leaf broom top, the Radix Astragali, Semen Cuscutae, Fructus Corni, radix cyathulae, Ligusticum wallichii, Drynaria rhizome powder are broken to 5~25 mesh, mixing adds
Enter 10~45% ethanol waters, 1: 10~1: 15,65~90 DEG C extract 2~4 times in solid-liquid ratio, and 1~5h, concentration are dry every time
It is dry, obtain medicinal extract B;
S3. the maca leaf uses growth period cauline leaf, and the natto uses 80~120 mesh natto powders, by the maca leaf and tree
The certain kind of berries, the mixing of calcium fruit, dry, pulverize to 80~120 mesh, are well mixed with natto powder, extractum A and B, homogeneous, obtain the dietotherapy
Composition.
5. preparation method according to claim 4, it is characterised in that solid-liquid ratio described in step S1 is 1:It is 12.5 described
Ethanol water concentration is 70~75%.
6. preparation method according to claim 4, it is characterised in that solid-liquid ratio described in step S2 is 1:It is 12.5 described
Ethanol water concentration is 25~30%.
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Application publication date: 20171226 |