CN107496662A - A kind of medicament for treating tinea pedis and preparation method thereof - Google Patents

A kind of medicament for treating tinea pedis and preparation method thereof Download PDF

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Publication number
CN107496662A
CN107496662A CN201710846360.7A CN201710846360A CN107496662A CN 107496662 A CN107496662 A CN 107496662A CN 201710846360 A CN201710846360 A CN 201710846360A CN 107496662 A CN107496662 A CN 107496662A
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China
Prior art keywords
tinea pedis
medicament
light
coloured vinegar
coptis
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Pending
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CN201710846360.7A
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Chinese (zh)
Inventor
尚圣杰
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Jieshou City Essence Sti Consultation Service Co Ltd
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Jieshou City Essence Sti Consultation Service Co Ltd
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Priority to CN201710846360.7A priority Critical patent/CN107496662A/en
Publication of CN107496662A publication Critical patent/CN107496662A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of medicament for treating tinea pedis, by weight, including following raw material:The coptis 5~8, pseudo-ginseng 4~6, erythrina bark 7~10, radix glycyrrhizae 3~5, garlic clove 8~12, light-coloured vinegar 25~30.The present invention is using garlic clove, light-coloured vinegar as primary raw material, and it is equipped with the Chinese herbal medicines such as the coptis, pseudo-ginseng, erythrina bark, the medicament of a treatment tinea pedis has been made, it has anti-inflammation, purging intense heat and detonicating, dissipate stasis of blood hemostasis, activating blood circulation and reducing swelling and other effects, the medicament of present invention treatment tinea pedis has extraordinary curative effect to tinea pedis, and cure rate is up to 89%, and total effective rate is more than 99%.

Description

A kind of medicament for treating tinea pedis and preparation method thereof
Technical field
The present invention relates to a kind of medicament for treating tinea pedis and preparation method thereof.
Background technology
Tinea pedis, also known as tinea pedis, it is that fungal infection causes, it is wet that clinical manifestation plays blister, decortication or skin whitening between toe It is soft, rotten to the corn or pachyderma, coarse, cracking are also may occur in which, and vola pedis and edge, itching can be spread to.Can with it is local suppurate, it is red Swollen, pain, inguinal lymphadenopathy, or even form the scabies secondary infection such as shank erysipelas and cellulitis.
Although in the prior art, having there is the Chinese medicine preparation of many treatment tinea pedis, most of preparations are required for using Very more Chinese medicines, and the raw material having is costly, and cost is higher, and market prospects are poor.
The content of the invention
The technical problems to be solved by the invention, which are to provide, a kind of is formulated that simple, cost is low, eutherapeutic treatment tinea pedis Medicament and preparation method thereof.
In order to solve the above-mentioned technical problem, the present invention adopts the following technical scheme that:A kind of medicament for treating tinea pedis, by weight Part, including following raw material:The coptis 5~8, pseudo-ginseng 4~6, erythrina bark 7~10, radix glycyrrhizae 3~5, garlic clove 8~12, light-coloured vinegar 25~30.
The preparation method of the medicament of above-mentioned treatment tinea pedis, comprises the following steps:
(1) garlic clove is cut into slices, be put into light-coloured vinegar, soaked 8~10 minutes, obtain light-coloured vinegar soak;
(2) coptis, pseudo-ginseng, erythrina bark and radix glycyrrhizae are mixed, adds hot water, soaked 15~20 minutes, obtain herbal medicine immersion Liquid;
(3) light-coloured vinegar soak is poured into herbal medicine immersion liquid, produces the medicament of the treatment tinea pedis.
The coptis, bitter are cold in nature.With heat-clearing and damp-drying drug, the effect of purging intense heat and detonicating.For damp and hot feeling of fullness, acid regurgitation is vomitted, is rushed down Dysentery, jaundice, unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, blood-head tells nosebleed, hot eyes, toothache, quench one's thirst, carbuncle swells furunculosis;Eczema is controlled outside, Wet sore, duct are suppurated.
Pseudo-ginseng, sweet, slight bitter are warm-natured.With dissipate stasis of blood hemostasis, the effect of detumescence ding-tong.For spitting blood, spit blood, bleeding from five sense organs or subcutaneous tissue, just Blood, uterine bleeding, traumatism and bleeding, chest and abdomen twinge, tumbling and swelling.
Erythrina bark, acrid flavour, hardship;It is mild-natured.With dispelling wind and eliminating dampness, water profitting, the effect of promoting blood circulation and detoxication.Cure mainly rheumatoid arthrosis Bitterly;Waist and leg ache;Edema due to deficiency of the kidney;Quench one's thirst;Epigastric pain;Traumatic injury;Fracture;Spit blood;Bleeding from five sense organs or subcutaneous tissue;Malaria;Dermatitis rhus;Osteomyelitis;It is deep Portion's purulence ulcer.
Radix glycyrrhizae, it is sweet, it is mild-natured.With invigorating the spleen and benefiting qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, the work(of coordinating the drug actions of a prescription Effect.For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, abirritant It is thing toxicity, strong.
Garlic clove, the sulphur compound contained have strong antibacterial and anti-inflammation functions, to a variety of coccuses, bacillus, fungi and virus Deng having suppression and killing action.
Light-coloured vinegar, there are sterilization, mould proof, sterilization, it can kill 99% bacterium, 82% mould and 80% disease Poison.
Beneficial effects of the present invention are:
1. the present invention is equipped with the Chinese herbal medicines such as the coptis, pseudo-ginseng, erythrina bark using garlic clove, light-coloured vinegar as primary raw material, one has been made Money treats the medicament of tinea pedis, and it has anti-inflammation, purging intense heat and detonicating, dissipate stasis of blood hemostasis, activating blood circulation and reducing swelling and other effects, available for treating pin Gas.
2. the present invention is free of antibiotic, the problem of will not causing to use poor resistance long, safely and effectively.
3. the medicament of present invention treatment tinea pedis has extraordinary curative effect to tinea pedis, cure rate is up to 89%, total effective rate More than 99%.
4. preparation method of the present invention is simple, easily implement, the therapeutic effect of each raw material and Chinese herbal medicine can be given full play to, be applicable In the extensive implementation of industrialization, and it is formulated simply, raw material are few, and cost is low, have extraordinary application prospect.
Embodiment
With reference to embodiment, the invention will be further described:
Various raw materials, are such as not specifically noted used in following examples, are commercially available prod well known in the art.
Embodiment 1
A kind of medicament for treating tinea pedis, by weight, it is made up of following raw material:The coptis 7, pseudo-ginseng 5, erythrina bark 8, radix glycyrrhizae 4, Garlic clove 10, light-coloured vinegar 28.
The preparation method of the medicament of above-mentioned treatment tinea pedis, comprises the following steps:
(1) garlic clove is cut into slices, be put into light-coloured vinegar, soaked 9 minutes, obtain light-coloured vinegar soak;
(2) coptis, pseudo-ginseng, erythrina bark and radix glycyrrhizae are mixed, by 1:5 solid-liquid ratio adds 65 DEG C of hot water, soaks 18 points Clock, obtain herbal medicine immersion liquid;
(3) light-coloured vinegar soak is poured into herbal medicine immersion liquid, produces the medicament of the treatment tinea pedis.
Embodiment 2
A kind of medicament for treating tinea pedis, by weight, it is made up of following raw material:The coptis 5, pseudo-ginseng 4, erythrina bark 7, radix glycyrrhizae 3, Garlic clove 8, light-coloured vinegar 25.
The preparation method of the medicament of above-mentioned treatment tinea pedis, comprises the following steps:
(1) garlic clove is cut into slices, be put into light-coloured vinegar, soaked 8 minutes, obtain light-coloured vinegar soak;
(2) coptis, pseudo-ginseng, erythrina bark and radix glycyrrhizae are mixed, by 1:6 solid-liquid ratio adds 60 DEG C of hot water, soaks 15 points Clock, obtain herbal medicine immersion liquid;
(3) light-coloured vinegar soak is poured into herbal medicine immersion liquid, produces the medicament of the treatment tinea pedis.
Embodiment 3
A kind of medicament for treating tinea pedis, by weight, it is made up of following raw material:The coptis 8, pseudo-ginseng 6, erythrina bark 10, radix glycyrrhizae 5th, garlic clove 12, light-coloured vinegar 30.
The preparation method of the medicament of above-mentioned treatment tinea pedis, comprises the following steps:
(1) garlic clove is cut into slices, be put into light-coloured vinegar, soaked 10 minutes, obtain light-coloured vinegar soak;
(2) coptis, pseudo-ginseng, erythrina bark and radix glycyrrhizae are mixed, by 1:4 solid-liquid ratio adds 70 DEG C of hot water, soaks 20 points Clock, obtain herbal medicine immersion liquid;
(3) light-coloured vinegar soak is poured into herbal medicine immersion liquid, produces the medicament of the treatment tinea pedis.
Embodiment 4
The clinical effect trial of the medicament of present invention treatment tinea pedis
MethodsThe cases enrolled:Through being diagnosed as tinea pedis, there is the one or more patient of tinea pedis clinical symptoms;
Usage and dosage is:Pin is steeped every night 1 time, decoction exceedes instep, 7 days courses for the treatment of.
Curative effect situation criterion:1. cure.Malaise symptoms are wholly absent;It is 2. effective.Malaise symptoms mitigate or part disappears Lose;It is 3. invalid.Malaise symptoms are unchanged.
Table 1 is the clinical pharrnacokinetics report of 300 tinea pedis patients.
Clinical effect trial result of the medicament of the present invention treatment tinea pedis of table 1 to tinea pedis
Group Medication number Healing number Efficiently individual quantity Invalid number Cure rate Total effective rate
Embodiment 1 100 89 11 0 89% 100%
Embodiment 2 100 82 18 0 82% 100%
Embodiment 3 100 87 12 1 87% 99%
Model case is as follows:
Pueraria lobota, man, 26 years old, in sick 2 years ages, between toe and sole played blister, itching, and rotten to the corn, red and swollen, pain occurs, makes After a course for the treatment of of the invention, red and swollen, pain disappears, and erosion takes a turn for the better, and is continuing with, after 4 courses for the treatment of, recovery from illness.Follow-up after 1 year Without recurrence, any side effect is had no.
Money, female, 29 years old, sick 1 year age, gestation was infected, and blister is played between toe, itching, decortication, uses the present invention one After the individual course for the treatment of, bubble is reduced, and gargalesthesia mitigates, and is continuing with, after 3 courses for the treatment of, recovery from illness.Follow-up has no any without recurrence after 1 year Side effect.
It should be understood that example as described herein and embodiment can be made only for explanation, those skilled in the art according to it Various modifications or change, in the case where not departing from spirit of the invention, belong to protection scope of the present invention.

Claims (2)

  1. A kind of 1. medicament for treating tinea pedis, it is characterised in that by weight, including following raw material:The coptis 5~8, pseudo-ginseng 4~6, Erythrina bark 7~10, radix glycyrrhizae 3~5, garlic clove 8~12, light-coloured vinegar 25~30.
  2. 2. the preparation method of the medicament for the treatment of tinea pedis as claimed in claim 1, comprises the following steps:
    (1) garlic clove is cut into slices, be put into light-coloured vinegar, soaked 8~10 minutes, obtain light-coloured vinegar soak;
    (2) coptis, pseudo-ginseng, erythrina bark and radix glycyrrhizae are mixed, adds hot water, soaked 15~20 minutes, obtain herbal medicine immersion liquid;
    (3) light-coloured vinegar soak is poured into herbal medicine immersion liquid, produces the medicament of the treatment tinea pedis.
CN201710846360.7A 2017-09-19 2017-09-19 A kind of medicament for treating tinea pedis and preparation method thereof Pending CN107496662A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112691079A (en) * 2021-01-27 2021-04-23 吉林医药学院 Foot bacteriostatic care solution containing traditional Chinese medicine extract and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105412650A (en) * 2015-12-09 2016-03-23 马凯 Medicine for treating dermatophytosis
CN106109870A (en) * 2016-07-27 2016-11-16 桐城市泰安中药材种植专业合作社 A kind of Chinese medicine treating squama type tinea pedis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105412650A (en) * 2015-12-09 2016-03-23 马凯 Medicine for treating dermatophytosis
CN106109870A (en) * 2016-07-27 2016-11-16 桐城市泰安中药材种植专业合作社 A kind of Chinese medicine treating squama type tinea pedis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
史德: "《盐醋葱姜蒜药用便方》", 30 April 2015, 金盾出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112691079A (en) * 2021-01-27 2021-04-23 吉林医药学院 Foot bacteriostatic care solution containing traditional Chinese medicine extract and preparation method thereof

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Application publication date: 20171222

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