CN107490726A - A kind of liquid or gel impedance bioelectrical measurement system and its information acquisition method - Google Patents

A kind of liquid or gel impedance bioelectrical measurement system and its information acquisition method Download PDF

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Publication number
CN107490726A
CN107490726A CN201610414767.8A CN201610414767A CN107490726A CN 107490726 A CN107490726 A CN 107490726A CN 201610414767 A CN201610414767 A CN 201610414767A CN 107490726 A CN107490726 A CN 107490726A
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China
Prior art keywords
impedance
gel
liquid
measurement system
bioelectrical measurement
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CN201610414767.8A
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Chinese (zh)
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陈瑞娟
冯彦博
戚昊峰
王慧泉
王金海
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Tianjin Polytechnic University
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Tianjin Polytechnic University
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R27/00Arrangements for measuring resistance, reactance, impedance, or electric characteristics derived therefrom
    • G01R27/02Measuring real or complex resistance, reactance, impedance, or other two-pole characteristics derived therefrom, e.g. time constant
    • G01R27/22Measuring resistance of fluids

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)

Abstract

The present invention provides a kind of the impedance bioelectrical measurement system and its information acquisition method of liquid or gel, belongs to the fields such as electronic information technology, biological medicine technology, mechanical device, system includes:Electrical impedance testing cassete, impedance bioelectrical measurement equipment and microprocessor.Liquid or gel are loaded into electrical impedance testing cassete, accessed by electrical impedance testing cassete both sides wire in testing impedance instrument or respective impedance test system, so as to obtain the impedance value and electrical conductivity, dielectric constant values of corresponding liquid or gel.Method includes:The solution or gel of various concentrations are matched, the impedance value tested respectively under various concentrations, the matching relationship between concentration and impedance is then obtained by way of curve matching, and then corresponding impedance value can be obtained by bringing specific concentration value into.Instant invention overcomes liquid or gel to have mobility, limitation in irregular shape, and electrode accesses the shortcomings that uneven in test process, the accuracy of liquid or gel impedance bioelectrical measurement is improved, improves the computational efficiency of other electrical characteristics indexs such as tester electrical conductivity.

Description

A kind of liquid or gel impedance bioelectrical measurement system and its information acquisition method
Technical field
The present invention belongs to the fields such as electronic information technology, biological medicine technology, mechanical device, more particularly to a kind of solution Or the impedance bioelectrical measurement system and its information acquisition method of gel.
Background technology
The research of bioelectromagnetics characteristic includes the specific directions such as electromagnetic radiation suffered by organism, electromagnetism diagnosis and treatment, wherein The preparation of the imitative body of biology is a part for its basic research, measures and obtains and meets the imitative body Models of organism true electrical characteristics and be Its key link.In view of convenience and style characteristic, widely used salting liquid or salt gel is real raw to replace in research Thing tissue.Because the concentration of solution or the electric conductivity solute of salt gel is relevant, opinions vary in the making of imitative body at present, has no Unified standard [1].Further, since the mobility of solution or salt gel, in irregular shape, for the conductivity measurement of measured object Accuracy decrease, simultaneously for measured object electric conductivity analysis correctness and analysis efficiency have a significant impact.
Bibliography:
The salting liquids electrical conductivity such as [1] Chen Limei, Cheng Minxi, Xiao Xiaofang and measurement [J] experiments of the relation of concentration and temperature Room research and discovery, 2010,29 (5):39-42.
The content of the invention
The present invention proposes the impedance bioelectrical measurement system and its information acquisition method of a kind of solution or gel, and the present invention realizes There is effective measurement of the liquid of mobility or the electrical impedance parameter of gel, so as to improving the standard of the measurement of measured object electrical impedance The efficiency of true property and electric conductivity analysis, it is described below:
A kind of impedance bioelectrical measurement system of liquid or gel includes:Testing impedance box, impedance bioelectrical measurement equipment and micro- place Manage device.Wherein,
The electrical impedance testing cassete, including:Cylinder outward appearance agent structure, the internal rule space for having receiving measured object, two Side is thread plug, thread plug combination electrode and wire, wherein,
Testing impedance box making material is insulator, and its size can be modified before making as the case may be.
The cavity, that is, the space of measured object is accommodated, is cylinder or prism.
The both sides thread plug is connected by helicitic texture with cylinder.
On the inside of the thread plug, i.e., the side contacted with measured object, with reference to electrode, thread plug central punch extraction wire.
The electrode is the preferable pellet electrode of electric conductivity.
The wire is with electrode by being weldingly connected.
A kind of electrical impedance information acquisition methods of solution or gel, the described method comprises the following steps:
(1) configuration salting liquid or salt gel are required according to the salting liquid of certain concentration or the different ratio of salt gel, respectively Measure the impedance value of the salting liquid or salt gel under each concentration;
(2) salting liquid of gained various concentrations or the impedance value of salt gel are entered using least square method or other algorithms The curve matching of row data, obtain concentration and electrical conductivity, the curve of dielectric constant;
(3) any concentration value brought into polynomial fitting described in (2) can obtain salting liquid under the concentration or salt coagulates The electrical conductivity of glue, dielectric constant values.
The beneficial effect of technical scheme provided by the invention is:
The invention provides the impedance bioelectrical measurement system and information acquisition method of a kind of solution or gel, instant invention overcomes The shortcomings that liquid or salt gel have mobility, limitation in irregular shape, and electrode access is uneven in test process, The accuracy of liquid or salt gel impedance bioelectrical measurement is improved, improves the calculating effect of other Scientific Indicators such as tester electrical conductivity Rate, make offer foundation for the imitative system of biological electrical characteristics research.
Brief description of the drawings
Fig. 1 is box body figure in the middle part of electrical impedance testing cassete;
Fig. 2 is thread plug figure;
Fig. 3 is electrical impedance testing cassete overall diagram;
Fig. 4 is liquid or gel impedance bioelectrical measurement system schematic;
Fig. 5 is electrical impedance testing cassete, electric impedance analyzer, the impedance measurement of computer composition, analysis system schematic diagram;
Fig. 6 is electrical impedance testing cassete, the impedance measurement system schematic diagram of Wheatstone bridge formula circuit composition;
Fig. 7 is the flow chart of a kind of liquid provided by the invention or gel electrical impedance information acquisition methods.
In accompanying drawing, the list of parts representated by each label is as follows:
2.1 be metal electrode;
2.2 it is wire via;
3.1 be wire;
3.2 be metal electrode.
Embodiment
To make the object, technical solutions and advantages of the present invention clearer, below in conjunction with accompanying drawing to embodiment party of the present invention Formula is described in further detail.
Inner chamber is chosen to be described exemplified by cylinder in Fig. 1,2,3.
Dimensional parameters can be set according to actual conditions in Fig. 1,2,3.
Fig. 1 is electrical impedance testing cassete central tubular figure, and Fig. 2 positions thread plug figure, it is overall that Fig. 3 show electrical impedance testing cassete Figure.
Observe Fig. 1,2,3 and understand that Fig. 3 is to be formed by connecting by Fig. 1,2 by helicitic texture.
As shown in figure 4, it is a kind of liquid or gel impedance bioelectrical measurement system and its information acquisition method.Its system is by impedance Testing cassete, impedance measurement device, computer composition.Testing impedance box connects impedance measurement device, is measured through impedance measurement device Impedance data imported into computer, using computer by data handled to obtain resistivity-solution concentration, dielectric constant- The relation of solution concentration, specific ginseng is had according to gained resistivity-solution concentration, the configuration of the relation of dielectric constant-solution concentration Several solution or gel.
Further, in order to meet a variety of needs in practical application, the testing impedance box in embodiment of the present invention is As shown in Figure 1, Figure 2 with the testing impedance box described by Fig. 3.
Further, in order to meet a variety of needs in practical application, testing impedance box in embodiment of the present invention Cavity can be selected as prism.
Further, in order to meet a variety of needs in practical application, testing impedance box in embodiment of the present invention Size can be formulated according to specific needs.
Further, in order to meet a variety of needs in practical application, the impedance measurement device in embodiment of the present invention It can select as the different devices with impedance measurement function.For example, impedance instrument, Wheatstone bridge formula circuit, rlc circuit Deng.
Further, in order to meet a variety of needs in practical application, through impedance measurement device in embodiment of the present invention Obtained data directly can imported into computer by the communication interface of impedance test device and computer, also can be by being manually entered To computer.
Further, in order to meet a variety of needs in practical application, resistivity-solution is dense in embodiment of the present invention Degree, dielectric constant-solution concentration relation can be coagulated by least square method or other algorithms to the salting liquid or salt of gained various concentrations The curve matching that the resistivity or dielectric constant values of glue carry out data obtains.
Illustrate a kind of use of electrical impedance testing cassete provided in an embodiment of the present invention with specific embodiment below, refer to It is described below:
Embodiment 1:
Fig. 5 is testing impedance box, electric impedance analyzer, the impedance measurement system schematic diagram of computer composition.System user Method is as follows:
(1) with the good solution to be measured of different gradient configurations or gel.
(2) testing cassete equipped with determinand is accessed into electric impedance analyzer after solution or gel reach stable state.
(3) obtained impedance data importing computer will be measured.
(4) solution is changed, repeats aforesaid operations.
(5) resistivity (ρ) and dielectric constant (ε) are calculated, according to following formula:
(6) regression analysis is carried out to resistivity (ρ) and dielectric constant (ε), obtains concentration-resistivity, concentration-dielectric constant Data fit equation.
(7) any concentration value is specified, the fit equation obtained by bringing into step (6), that is, obtains the resistance under the concentration Rate and dielectric constant values.
Embodiment 2:
Fig. 6 is the impedance measurement system schematic diagram of testing impedance box and Wheatstone bridge composition.
Symbol description is as follows in figure:
(1) AB is uniform slide wire resistance;
(2) R1 is variable resistor;
(3) F is the variable capacitance being connected in parallel on R1, it is therefore intended that realizes impedance balance with testing impedance box;
(4) M is the testing impedance box for being placed with solution to be measured, if its impedance is Zx;
(5) I is the AC power for having certain frequency, and it is 50KHz generally to take its frequency;
(6) G is earphone (or cathode ray oscilloscope);
System Utilization Procedure is as follows:
(1) with the good solution to be measured of different gradient configurations or gel.
(2) testing cassete equipped with determinand is accessed into Wheatstone bridge formula circuit after solution or gel reach stable state.
(3) after switching on power, mobile access point C, until sound minimum (or no current passes through in oscillograph) is in earphone Only.At this moment the voltage that 2 points of D, C is equal, and electric current is almost nil in DGC circuits, and at this moment electric bridge reaches balance.
(4) following relation is applied:
Z1=R1+jωF
Zx=Rx+jωCx
Z3=R3, Z4=R4
Z1Z4=ZxZ3
It is computed obtaining:
R3 in formula, R4 are respectively AC, and the resistance of BC sections, R1 is the resistance of variable resistance, can be measured from experiment, root According to following relation:
So as to obtain the resistivity of solution or gel in testing impedance box (ρ) and dielectric constant (ε).
(5) by measurement data input computer.
(6) solution is changed, repeats aforesaid operations.
(7) regression analysis is carried out to resistivity (ρ) and dielectric constant (ε), obtains concentration-resistivity, concentration-dielectric constant Data fit equation.
(8) any concentration value is specified, the fit equation obtained by bringing into step (7), that is, obtains the resistance under the concentration Rate and dielectric constant values.
It will be appreciated by those skilled in the art that accompanying drawing is the schematic diagram of a preferred embodiment, the embodiments of the present invention Sequence number is for illustration only, does not represent the quality of embodiment.
The foregoing is only presently preferred embodiments of the present invention, be not intended to limit the invention, it is all the present invention spirit and Within principle, any modification, equivalent substitution and improvements made etc., it should be included in the scope of the protection.

Claims (10)

1. the impedance bioelectrical measurement system of a kind of liquid or gel, it is characterised in that the impedance bioelectrical measurement system includes:Impedance is surveyed Try box, impedance bioelectrical measurement equipment and microprocessor.Wherein,
The testing impedance box is surveyed built with certain density tested salting liquid or salt gel using impedance bioelectrical measurement equipment Measure its impedance value;The testing cassete has specific shape, and can calculate its internal salting liquid or salt according to the law of resistance coagulates The resistivity and dielectric constant of glue;By the resistivity or dielectric constant values input microprocessor of the salting liquid or salt gel, lead to The concentration for changing the tested salting liquid or salt gel is crossed, obtains the salting liquid of series of discrete concentration value or the resistance of salt gel Rate or dielectric constant values;The microprocessor is handled data, can obtain salting liquid or salt gel under any concentration Resistivity or dielectric constant values.
2. the impedance bioelectrical measurement system of a kind of liquid according to claim 1 or gel, it is characterised in that the impedance is surveyed Trying box is specially:There is the regular cavity for accommodating measured object cylinder outward appearance agent structure, inside, and both sides are thread plug, thread plug knot The electrode of bottom surface all standing is closed, and is connected by wire with impedance measurement system.
3. the impedance bioelectrical measurement system of a kind of liquid according to claim 1 or gel, it is characterised in that the impedance is surveyed Trying box is specially:Making material is insulator, and its size can be modified before making as the case may be.
4. the impedance bioelectrical measurement system of a kind of liquid according to claim 1 or gel, it is characterised in that the impedance is surveyed Trying box is specially:The cavity, that is, the space of measured object is accommodated, is cylinder or prism.
5. the impedance bioelectrical measurement system of a kind of liquid according to claim 1 or gel, it is characterised in that the impedance is surveyed Trying box is specially:The both sides thread plug is connected by helicitic texture with cylinder.
6. the impedance bioelectrical measurement system of a kind of liquid according to claim 1 or gel, it is characterised in that the impedance is surveyed Trying box is specially:On the inside of the thread plug, i.e., the side contacted with measured object, with reference to electrode, thread plug central punch is drawn and led Line.
7. the impedance bioelectrical measurement system of a kind of liquid according to claim 1 or gel, it is characterised in that the impedance is surveyed Trying box is specially:The electrode is the preferable pellet electrode of electric conductivity.
8. the impedance bioelectrical measurement system of a kind of liquid according to claim 1 or gel, it is characterised in that the impedance is surveyed Trying box is specially:The wire is with electrode by being weldingly connected.
9. the impedance bioelectrical measurement system of a kind of liquid according to claim 1 or gel, it is characterised in that the electrical impedance Measuring apparatus is specially:Electric impedance analyzer, RLC measuring circuits or wheatstone bridge circuits.
10. the information acquisition method of the impedance bioelectrical measurement system of a kind of liquid according to claim 1 or gel, its feature It is, the described method comprises the following steps:
(1) configuration salting liquid or salt gel are required according to the salting liquid of certain concentration or the different ratio of salt gel, measured respectively The impedance value of salting liquid or salt gel under each concentration;
(2) line number is entered to the salting liquid of gained various concentrations or the impedance value of salt gel using least square method or other algorithms According to curve matching, obtain concentration and electrical conductivity, the curve of dielectric constant;
(3) salting liquid under the concentration or salt gel can be obtained by bringing any concentration value into described in (2) polynomial fitting Electrical conductivity, dielectric constant values.
CN201610414767.8A 2016-06-12 2016-06-12 A kind of liquid or gel impedance bioelectrical measurement system and its information acquisition method Pending CN107490726A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110780123A (en) * 2018-07-24 2020-02-11 阿自倍尔株式会社 Conductivity meter
CN111289583A (en) * 2020-02-19 2020-06-16 华北电力大学 Device and method for testing broadband dielectric property of gel material
CN112432975A (en) * 2021-01-26 2021-03-02 南京壹净新材料科技有限公司 Method for measuring liquid conductivity

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CN101135705A (en) * 2006-08-30 2008-03-05 梅特勒-托利多仪器(上海)有限公司 Measurement method of solution electric conductivity
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CN2069567U (en) * 1990-04-03 1991-01-16 常州市佳乐电子仪器厂 Liquid dielectric resistivity/resistance tester
CN101135705A (en) * 2006-08-30 2008-03-05 梅特勒-托利多仪器(上海)有限公司 Measurement method of solution electric conductivity
CN202285030U (en) * 2011-11-07 2012-06-27 四川大学华西医院 Solution electrical conductivity measuring device
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110780123A (en) * 2018-07-24 2020-02-11 阿自倍尔株式会社 Conductivity meter
CN110780123B (en) * 2018-07-24 2022-02-25 阿自倍尔株式会社 Conductivity meter
CN111289583A (en) * 2020-02-19 2020-06-16 华北电力大学 Device and method for testing broadband dielectric property of gel material
CN112432975A (en) * 2021-01-26 2021-03-02 南京壹净新材料科技有限公司 Method for measuring liquid conductivity

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