CN107485599A - The not fluorine-containing children's toothpaste of safety edible - Google Patents

The not fluorine-containing children's toothpaste of safety edible Download PDF

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Publication number
CN107485599A
CN107485599A CN201710781690.2A CN201710781690A CN107485599A CN 107485599 A CN107485599 A CN 107485599A CN 201710781690 A CN201710781690 A CN 201710781690A CN 107485599 A CN107485599 A CN 107485599A
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toothpaste
children
fluorine
safety
safety edible
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郑绍辉
彭超
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Southwest University
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Southwest University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25Silicon; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/986Milk; Derivatives thereof, e.g. butter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30Characterized by the absence of a particular group of ingredients

Abstract

The present invention relates to a kind of not fluorine-containing children's toothpaste of safety edible, its composition includes NMF, rubbing agent, thickener, preservative, foaming agent, spices, lubricant, sweetener, milk calcium, citric acid, deionized water.Safety edible of the present invention component contained by not fluorine-containing children's toothpaste is food-grade, without any toxicity and side effects;Raw materials used proportioning, which has, strictly to be considered, and highlights selection and the reason of the dosage that rubbed in the present invention.Children can reach the effect to take care of one's teeth well using during this toothpaste, again will not damaging delicate tooth, and children's imprudence this toothpaste of eating will not also bring any side effect.

Description

The not fluorine-containing children's toothpaste of safety edible
Technical field
The invention belongs to commodity technical field, is related to a kind of not fluorine-containing children's toothpaste of safety edible.
Background technology
In recent years, with the significant increase of people's living standard, eating habit has very big change, the health thus brought Problem is also more and more, and wherein dental health problems have turned into the importance of puzzlement people.Children since birth just There can be good living condition, diet is also very abundant, and still, the originally fragile tooth of children increasingly enriches in food It is faced with very big disease risks today.According to investigations, China's year children's Primary Caries tooth rate has reached surprising 66%, and has Elevated trend year by year.Therefore, the children's toothpaste for being directed to solving teenager teeth health problem increasingly receives an acclaim, and also has Great market potential.
The difference of children's toothpaste and adult's toothpaste is that children's toothpaste has used gentleer composition, have adjusted toothpaste Composition, it is therefore intended that avoiding too strong excitant or children in adult's toothpaste may eat the negative effect that toothpaste is brought.When So, the composition of children's toothpaste be based on adult toothpaste, simply remove or reduce accordingly part may give teenager teeth or The composition that body is negatively affected, although this can reduce the effect once of such as cleannes to a certain extent, this is to youngster It is necessary for virgin originally fragile tooth.
Children's toothpaste mainly includes following raw material:
NMF --- NMF can prevent toothpaste cure hard in dentifrice tube, toothpaste is always maintained at stability and certain Mobility, be both easy to manufacturer production to sell, and be easy to consumer to use again.Conventional NMF has glycerine, propane diols, sorbierite Deng, meanwhile, they all have certain sweet taste, can increase the mouthfeel of toothpaste very well.This has good rush for children's toothpaste Enter effect.In addition, sorbierite can improve the index of refraction of children's toothpaste, the transparency of toothpaste is lifted, increase toothpaste is to children's Attraction.NMF also such as adjusts oral cavity PH, plays certain buffering and other effects.
The effect of thickener --- thickener is to make toothpaste stable system, prevents short grained sedimentation, have toothpaste tactile Denaturation and pseudoplastic behavior.Common thickener has CMC, xanthans etc., and they can make lotion of toothpaste have the effect and more of preferably seeping water High thickening efficiency, while also have more preferable glossiness.
Preservative --- due to toothpaste production, storage, transport, sale etc. during inevitably by microorganism Pollution, and the nutriment in toothpaste provides good condition for the growth and breeding of microorganism, ultimately results in toothpaste corruption It is rotten, so the use of preservative is essential.When microbial reproduction to certain amount, toothpaste can produce Solid-Liquid Separation, become Color, stink etc. is produced, or even spread disease.The use of preservative can suppress the growth and breeding of microorganism, the guarantor for extending toothpaste Deposit the time.The preservative commonly used in toothpaste has benzoic acid, sorbic acid and their salt, para hydroxybenzene acid adding esters etc..Youngster In virgin toothpaste, the dosage of preservative should be less than adult's toothpaste, and the species for choosing preservative should select the type that gently has no side effect.
Rubbing agent --- for increasing the friction between tooth and lotion of toothpaste, so as to play the composition of cleaning action.Mesh The preceding wearability for evaluating formulation of tooth-paste mainly has two big indexs:Relative Dentine wearability, relative enamel wearability.But mesh Before go back the special standard pin of neither one to children's toothpaste, the ratio so the children's toothpaste abrasive content and species of in the market seem It is more in disorder.The rubbing agent of children's toothpaste mainly has calcium carbonate, calcium phosphate, aluminium hydroxide, silica etc..Calcium carbonate production method Simply, it is cheap, but there is the shortcomings of color and luster is bad, and hardness is big, and particle is thick, and impurity is more;Calcium phosphate has with the fluorine in toothpaste Preferable intermiscibility, but there is larger abrasion to tooth, and pH value is higher, oral environment that can be sensitive to children causes to pierce Swash;Aluminium hydroxide light weight, property is stable, and white appearance is in good taste, but generally white using the lotion of toothpaste of aluminium hydroxide Color, do not liked by children, while the aluminium in aluminium hydroxide can make children have the danger of poisoning by aluminum.Silica is a kind of neutral Gentle rubbing agent, there is preferable frictional property while do not damage teenager teeth, while the index of refraction of its index of refraction and sorbierite etc. connects Closely, can be used for manufacturing transparent or gel shape toothpaste, it is deep enjoyed by children.
Foaming agent --- foaming agent is the important component of toothpaste, and it is the washing for increasing toothpaste to dental surface that it, which is acted on, Effect.Foaming agent can not only reduce the surface tension of water, moreover it is possible to play the effects such as moistening, foaming, emulsification, washing and decontamination.Mesh The foaming agent generally used in preceding toothpaste is lauryl sodium sulfate, sodium N-lauroyl sarcosinate, sodium cocoyl glycinate etc..
The effect of spices --- spices is to lift the use feeling of user.Part spices has bactericidal action.Common perfume (or spice) Material has mint aroma, spearmint type, special odor type etc..It is but unfavorable because these odor types more or less have certain stimulation In being used in children's toothpaste.Fruit flavouring is gentleer, compares and is adapted to use in children's toothpaste.
The effect of pigment --- pigment is to cover the coloured composition in toothpaste, beautifies lotion of toothpaste.Pigment in toothpaste is big Three classes can be divided on body:Synthetic dyestuff, inorganic pigment, animals and plants natural pigment.The selection of pigment can be carried out according to being actually needed, Children's toothpaste is typically without using synthetic dyestuff.
The effect of sweetener --- sweetener is while toothpaste taste is lifted, and covers other offending tastes.Often Toothpaste sweetener has saccharin sodium, acesulfame potassium, Sucralose, sweetener etc..
Functional additive --- the effect of functional additive is to supplement the material needed for tooth, children's toothpaste in toothpaste The effect of middle functional additive is to aid in the dental health growth of children.The dimension life that tooth is good in nutrition is added such as into children's toothpaste Element and mineral matter are capable of the nutrition system of complete tooth, firm tooth, while can also prevent various periodontosis;Vitamin E vinegar Acid esters is applied can protect dental tissue in toothpaste, promote dental health;Adding fluoride being capable of pre- anti-caries.
With increasing in the market toothpaste species, the toothpaste species released for children is also a feast for the eyes.But big portion Divide children's toothpaste that all simply packaging is changed or increased and reduce Cucumber, i.e., " offer the same old stuff but with a different label ", this really to be adapted to The toothpaste that children use becomes rare.
Tooth is made up of the dental pulp inside enamel, dentine, cementum and pulp cavity, teenager teeth and adult tooth knot Structure is identical, and composition is also roughly the same, and the main distinction is that teenager teeth is smaller and enamel is with respect to hypoplasia.For maturation Enamel, chemical composition is:Inorganic salts(Mass fraction 96-97%, the phosphorite crystal of most calcic and phosphorus and few Other phosphate crystals of amount etc.), organic matter(Mass fraction is less than 1%, volume fraction about 2%, including protein and lipid, egg White matter is divided into amelogenin, non-amelogenin, the class of protease three), water(Mass fraction 2-4%, volume fraction about 12%, wherein greatly Part is to combine water, and minority is free water).For enamel hypoplasia:Refer to enamel in growth course, by some The influence of systemic or local sexual factor and the enamel structure that occurs is abnormal, be mainly shown as tooth discoloration and enamel defect.
The common children's toothpaste abrasive content of in the market is generally in more than 15wt%, such as a kind of patent " edible natural Children's toothpaste and preparation method "(The patent No.:CN 105832614 A)Abrasive content 15%-25%;" natural fluorine-free edible Transparent child health care toothpaste(The patent No.:CN 101889970 A)Abrasive content 8%-20%;" natural fluorine-free edible transparent Child nutrition toothpaste(The patent No.:CN 101889969 A )" abrasive content 8%-20%;" the edible youngster without saccharin sodium and fluorine Virgin alkalescent is replenished the calcium toothpaste "(The patent No.:CN 105078782 A)Abrasive content 40%-47%, abrasive content is higher, easily Damage children are in the tooth in long teeth stage.On the other hand external Orajel children's toothpastes do not have rubbing agent, cleaning effect completely Fruit is bad.
Because the children of age very little are easy to swallow in toothpaste during brushing teeth, if containing fluorine in toothpaste, swallow Behavior children will be caused to produce dental fluorosis, or even growth effect health is influenceed, so needing to wait children basic after three years old The custom brushed teeth and do not swallowed can be formed, is just necessary to use the toothpaste containing certain fluoride.
The content of the invention
In view of this, it is an object of the invention to provide a kind of not fluorine-containing children's tooth of the safety edible used for children Cream.
To achieve the above object, the present invention provides following technical scheme:
The not fluorine-containing children's toothpaste of safety edible, is calculated according to the toothpaste gross mass percentage, including following percentage composition Component:NMF 50-70%, rubbing agent 2-6%, thickener 0.4-1.2%, preservative 0.1-0.3%, foaming agent 0.8-1.2% are fragrant Expect 0.8-1.5%, lubricant 0.05-0.2%, sweetener 0.2-2%, milk calcium 0.5-1.5%, citric acid 0.01-0.08%, deionization Water surplus, total amount 100%.
Further, the rubbing agent is one kind in calcium carbonate, calcium phosphate, aluminium hydroxide, silica, hydrated silica It is or several;The NMF is the one or more in sorbierite, glycerine, propane diols.
Further, the thickener be cellulose gum, CMC, xanthans, one kind in HPG or It is several.
Further, the preservative is the one or more of benzoic acid, sorbic acid, propionic acid and its esters.
Further, the foaming agent is in poloxamer188,120,000 base sodium sulphate, sodium N-lauroyl sarcosinate One or more.
Further, the sweetener is the one or more in saccharin sodium, acesulfame potassium, sweetener, Sucralose.
Further, the lubricant is dimethione;The milk calcium is the day directly extracted from milk So high lactoprotein calcium of activity.
Preferably, calculated according to the toothpaste gross mass percentage, include the component of following percentage composition:Sorbierite: 40.0%, glycerine:20.0%, propane diols:7.0%, hydrated silica:4.0%, poloxamer188:1.0%, cellulose carboxylic first Ether:0.8%, potassium sorbate:0.2%, spices:1.2%, saccharin sodium:0.1%, dimethione:0.05%, milk calcium:1.2% , citric acid:0.05%, deionized water:Surplus, total amount 100%.
Further, all components are food-grade, in process of production strict implement state food health and Safety standard.
Further, routinely prepared by children's toothpaste herbal paste formula for the toothpaste.
The method have the characteristics that:
1. not fluorine-containing is because the children of age very little are easy to swallow in toothpaste during brushing teeth, cause dental fluorosis, even Growth effect health is influenceed, so needing children are basic after three years old can form the custom brushed teeth and do not swallowed, is just necessary out Begin to use the toothpaste containing certain fluoride.So this toothpaste positions audient the children of 1-3 year.
2. another innovative point of the present invention is, the irrational feelings of content of rubbing agent are used in the market children's toothpaste Condition, this toothpaste set abrasive content in this ratio of 2%-6%, that is, have given up many children's toothpastes of in the market and be free of rubbing agent Way, do not adopt yet Among Children toothpaste use 10% or even more than 40% rubbing agent way.In children's tooth of this ratio It cream abrasive content, both can guarantee that teenager teeth can obtain effective cleaning, while the fragile tooth of children will not be damaged again.
3. water content of the present invention is more, thus children in oneself or parent's guiding in use, without first by toothbrush or toothpaste Adhesional wetting, need not also be gargled with water in advance, and appropriate extrusion is directly brushed teeth, can so reach optimal using effect, avoid Excessive moisture reduces the using effect of toothpaste.
4. milk calcium is with the addition of in formula, it is therefore intended that supplement the calcium ion of dental surface, realize self repairing for enamel It is multiple, strengthen tooth intensity.
Brief description of the drawings
In order that the purpose of the present invention, technical scheme and beneficial effect are clearer, the present invention provides drawings described below and carried out Explanation:
Fig. 1 is the not fluorine-containing children's toothpaste raw material proportioning of safety edible that embodiment 1 provides.
Embodiment
In order that the objects, technical solutions and advantages of the present invention are more intuitively understood, the present invention is carried out below further Describe in detail.
The not fluorine-containing children's toothpaste of safety edible is calculated by mass percentage, and formula is as follows comprising composition:
Sorbierite:40.0%, glycerine:20.0%, propane diols:7.0%, hydrated silica:4.0%, poloxamer188:1.0%, Cellulose gum:0.8%, potassium sorbate:0.2%, spices:1.2%, saccharin sodium:0.1%, dimethione:0.05% , milk calcium:1.2%, citric acid:0.05%, deionized water:Surplus.Total amount 100%.
Selected raw material is food-grade in the present embodiment, and children are using the not fluorine-containing children's toothpaste of safety edible During will not produce side effect.Routinely the children's toothpaste mode of production produces this toothpaste.
Hydrated silica in the present invention, play friction and go stain, frictional force is smaller, can effectively clean teenager teeth, again Tooth that will not be fragile to children brings damage.
Sorbierite is NMF and sweetener in the present invention, and main function is to prevent lotion moisture evaporation, prevents lotion from doing It is dry, be hardened, toothpaste can be always maintained at stability and certain mobility, the effect of ensure that toothpaste.Meanwhile sorbierite carries one Fixed sweet taste, the mouthfeel of this toothpaste can be increased.In addition, sorbierite can increase the light transmittance of lotion of toothpaste, increase the saturating of toothpaste Lightness.
Glycerine is NMF and sweetener in the present invention, acts on similar sorbierite, but its hygroscopicity is strong compared with sorbierite, can protect Lotion outward appearance is held to moisten;There is certain sweet taste simultaneously, flavor is added to toothpaste.
Propane diols is NMF and sweetener in the present invention, and it is the moisture for lifting lotion that it, which is acted on, extends lotion because of length The dry and hard time occurs in atmosphere for phase exposure;Also there is certain sweet taste simultaneously, lotion of toothpaste mouthfeel can be lifted.
Poloxamer188 is foaming agent, dispersant and lubricant in the present invention, and its main function is to make lotion of toothpaste various Composition spreads out, and keeps uniformity, while it also has lubrication.
Cellulose gum is thickener, adhesive, stabilizer in the present invention, and its main function is increase lotion of toothpaste Viscosity, it is easy to use, is unlikely to make lotion mobility too strong.
Potassium sorbate is preservative in the present invention, and as a kind of safe preservative being widely recognized as, its main function is Increase the holding time of this toothpaste, ensure the effect in service life of toothpaste.
Spices of the present invention is the tangerine oil of fruit type, and tangerine oil is all-natural product, comfortable as toothpaste is strengthened in toothpaste Property and mouthfeel composition, the effect of spices makes the use feeling of increase user, strengthens using effect.Meanwhile spices has necessarily Bacteriostasis.
Saccharin sodium is aromatic in the present invention, and it is the mouthfeel for lifting this children's toothpaste that it, which is acted on, increases the attraction to audient Power.
Dimethione is lubricant and defoamer in the present invention, and it is the degree of lubrication for increasing lotion of toothpaste that it, which is acted on, The damage that secondary friction is brought to tooth during brushing teeth is reduced simultaneously;The caused foaming in toothpaste making process is eliminated, is ensured The tight ness rating of lotion of toothpaste.
Milk calcium is hardening agent in the present invention, is the high lactoprotein calcium of the day natural activity directly extracted from milk, by There are abundant lactose and albumen in milk, therefore its absorptivity is much higher than other common calcium, it, which is acted on, is provided to tooth High-quality calcium supplement, improves tooth calcification capacity.
Citric acid is antioxidant, bacteriostatic agent, flavouring in the present invention, and it is the oxidation for slowing down toothpaste component that it, which is acted on, is prolonged Long usage time, while it also plays the role of certain bacteria growing inhibiting breeding, also corrects toothpaste peculiar smell, ensures toothpaste opening The effect of sense.
Children, in use, without first bedewing toothbrush or toothpaste, need not also be gargled with water in advance in oneself or parent guiding, Appropriate extrusion is directly brushed teeth, can so reach optimal using effect, avoiding excessive moisture reduces making for toothpaste Use effect.

Claims (10)

1. the not fluorine-containing children's toothpaste of safety edible, it is characterised in that calculated according to the toothpaste gross mass percentage, including such as The component of lower percentage composition:NMF 50-70%, rubbing agent 2-6%, thickener 0.4-1.2%, preservative 0.1-0.3%, foaming agent 0.8-1.2%, spices 0.8-1.5%, lubricant 0.05-0.2%, sweetener 0.2-2%, milk calcium 0.5-1.5%, citric acid 0.01- 0.08%, deionized water surplus, total amount 100%.
2. the not fluorine-containing children's toothpaste of safety edible according to claim 1, it is characterised in that the rubbing agent is carbonic acid One or more in calcium, calcium phosphate, aluminium hydroxide, silica, hydrated silica;The NMF is sorbierite, glycerine, third One or more in glycol.
3. the not fluorine-containing children's toothpaste of safety edible according to claim 1, it is characterised in that the thickener is fiber One or more in plain carboxylic methyl ether, CMC, xanthans, HPG.
4. the not fluorine-containing children's toothpaste of safety edible according to claim 1, it is characterised in that the preservative is benzene first Acid, sorbic acid, the one or more of propionic acid and its esters.
5. the not fluorine-containing children's toothpaste of safety edible according to claim 1, it is characterised in that the foaming agent is pool Lip river One or more in husky nurse 407, lauryl sodium sulfate, sodium N-lauroyl sarcosinate.
6. the not fluorine-containing children's toothpaste of safety edible according to claim 1, it is characterised in that the sweetener is saccharin One or more in sodium, acesulfame potassium, sweetener, Sucralose.
7. the not fluorine-containing children's toothpaste of safety edible according to claim 1, it is characterised in that the lubricant is poly- two First siloxanes;The milk calcium is the high lactoprotein calcium of natural activity directly extracted from milk.
8. the not fluorine-containing children's toothpaste of safety edible according to claim any one of 1-7, it is characterised in that according to described Toothpaste gross mass percentage calculates, and includes the component of following percentage composition:Sorbierite:40.0%, glycerine:20.0%, the third two Alcohol:7.0%, hydrated silica:4.0%, poloxamer188:1.0%, cellulose gum:0.8%, potassium sorbate:0.2%, Spices:1.2%, saccharin sodium:0.1%, dimethione:0.05%, milk calcium:1.2%, citric acid:0.05%, deionization Water:Surplus, total amount 100%.
9. the not fluorine-containing children's toothpaste of safety edible according to claim any one of 1-8, it is characterised in that described all Component is food-grade, in process of production the health and safety standard of strict implement state food.
10. the not fluorine-containing children's toothpaste of safety edible according to claim any one of 1-9, it is characterised in that the tooth Routinely prepared by children's toothpaste herbal paste formula for cream.
CN201710781690.2A 2017-09-02 2017-09-02 The not fluorine-containing children's toothpaste of safety edible Pending CN107485599A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021067994A1 (en) * 2019-09-30 2021-04-08 The Procter & Gamble Company Fluoride-free anticavity oral care compositions
US11918681B2 (en) 2019-09-30 2024-03-05 The Procter & Gamble Company Oral care compositions comprising hops beta acid and amino acid

Citations (4)

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CN101889969A (en) * 2009-05-20 2010-11-24 广州薇美姿个人护理用品有限公司 Natural fluorine-free edible transparent child nutrition toothpaste
CN103690381A (en) * 2013-12-19 2014-04-02 栾晓健 Fruity toothpaste for children
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WO2021067994A1 (en) * 2019-09-30 2021-04-08 The Procter & Gamble Company Fluoride-free anticavity oral care compositions
US11690792B2 (en) 2019-09-30 2023-07-04 The Procter & Gamble Company Oral care compositions comprising hops beta acids and metal ions
US11696881B2 (en) 2019-09-30 2023-07-11 The Procter & Gamble Company Oral care compositions comprising hops beta acids and fluoride ions
US11918681B2 (en) 2019-09-30 2024-03-05 The Procter & Gamble Company Oral care compositions comprising hops beta acid and amino acid

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