CN107469007A - 一种治疗关节疼痛的外用药物及其制备方法 - Google Patents

一种治疗关节疼痛的外用药物及其制备方法 Download PDF

Info

Publication number
CN107469007A
CN107469007A CN201710802288.8A CN201710802288A CN107469007A CN 107469007 A CN107469007 A CN 107469007A CN 201710802288 A CN201710802288 A CN 201710802288A CN 107469007 A CN107469007 A CN 107469007A
Authority
CN
China
Prior art keywords
root
radix
medicine
chinese
arthralgia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201710802288.8A
Other languages
English (en)
Inventor
罗兴贵
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chengdu Xing More Biotechnology LLC
Original Assignee
Chengdu Xing More Biotechnology LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chengdu Xing More Biotechnology LLC filed Critical Chengdu Xing More Biotechnology LLC
Priority to CN201710802288.8A priority Critical patent/CN107469007A/zh
Publication of CN107469007A publication Critical patent/CN107469007A/zh
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125Camphor; Nuclear substituted derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/583Snakes; Lizards, e.g. chameleons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/646Arachnids, e.g. spiders, scorpions, ticks or mites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/648Myriapods, e.g. centipedes or millipedes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • A61K36/126Drynaria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237Notopterygium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486Millettia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716Clematis (leather flower)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/83Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884Arisaema, e.g. Jack in the pulpit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Insects & Arthropods (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

本发明属于中药制剂领域,目的是根据中医治疗关节疼痛的认识机理而提供一种治疗关节疼痛的外用药物,所述药物的各个组分及其质量份比如下:酒炒桑枝100~180g、桂枝20~80g、夏天无60~150g、独活30~120g、羌活100~280g、桑寄生100~180g、当归80~180g、三七30~100g、桃仁80~160g、红花30~120g、川断90~160g、骨碎补100~250g、制川乌20~50g、粉葛根90~160g、狗骨20~50g、杜仲60~150g、牛膝150~300g、樟脑10~25g、肉桂20~60g、薏苡仁90~350g、木瓜50~100g、大黄30~300g、祖司麻50~150g、片姜黄30~100g、威灵仙60~100g、舒筋草250~1000g、鸡血藤100~180g、细辛10~50g、南星30~100g、土鳖虫30~100g、蜈蚣20~60g、乌梢蛇90~150g等,本发明提供的药物是一个很好的中药组方。

Description

一种治疗关节疼痛的外用药物及其制备方法
技术领域
本发明属于中药制剂领域,具体涉及一种治疗关节疼痛的外用药物,特别是供关节疼痛患者使用的外用药物及其制备方法的领域。
背景技术
据有关资料显示:关节疼痛,关节疼痛主要是由于关节炎或关节病引起的。关节疼痛牵涉范围非常广泛并且种类繁多,因此关节疼痛的鉴别诊断至关重要。关节痛在中医病症中属于肢节痛、肢节肿痛、痹证、痛风等病症范畴。另关节疼痛见《灵枢·百病始生》:“六经不通四肢,则肢节痛,腰脊乃强。”
那么,就如何找到一种可效治疗关节疼痛的中药组合物,是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗关节疼痛上,人们逐渐意识到了中医治疗关节疼痛的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗关节疼痛的现状,本发明的目的是在于提供一种治疗关节疼痛的外用药物,以解决关节疼痛患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗上述关节疼痛。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种治疗关节疼痛的外用药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
酒炒桑枝100~180g、桂枝20~80g、夏天无60~150g、独活30~120g、羌活100~280g、桑寄生100~180g、当归80~180g、三七30~100g、桃仁80~160g、红花30~120g、川断90~160g、骨碎补100~250g、制川乌20~50g、粉葛根90~160g、狗骨20~50g、杜仲60~150g、牛膝150~300g、樟脑10~25g、肉桂20~60g、薏苡仁90~350g、木瓜50~100g、大黄30~300g、祖司麻50~150g、片姜黄30~100g、 威灵仙60~100g、舒筋草250~1000g、鸡血藤100~180g、细辛10~50g、南星30~100g、土鳖虫30~100g、蜈蚣20~60g、乌梢蛇90~150g、秦艽50~150g、全虫30~70g、防风80~160g、白芷50~180g、赤芍60~180g、虎杖90~160g、粉萆薢90~160g、乳香(醋制)30~120g、没药(醋制)30~120g、附子(制)50~150g、透骨草90~160g、延胡索80~160g、细辛10~50g、自然铜(醋煅)50~180g、白屈菜50~180g。
一种治疗关节疼痛的外用药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
酒炒桑枝115~150g、桂枝26~70g、夏天无70~130g、独活36~105g、羌活115~250g、桑寄生115~150g、当归90~150g、三七36~90g、桃仁90~130g、红花36~105g、川断100~130g、骨碎补115~220g、制川乌26~42g、粉葛根100~130g、狗骨26~42g、杜仲70~130g、牛膝180~260g、樟脑11~22g、肉桂26~52g、薏苡仁100~320g、木瓜58~90g、大黄38~260g、祖司麻58~130g、片姜黄36~90g、 威灵仙70~90g、舒筋草220~850g、鸡血藤115~150g、细辛11~42g、南星38~90g、土鳖虫36~90g、蜈蚣26~52g、乌梢蛇100~130g、秦艽58~130g、全虫42~52g、防风100~115g、白芷68~130g、赤芍80~130g、虎杖100~130g、粉萆薢100~140g、乳香(醋制)36~105g、没药(醋制)36~105g、附子(制)58~130g、透骨草100~130g、延胡索90~140g、细辛11~42g、自然铜(醋煅)58~150g、白屈菜58~150g。
一种治疗关节疼痛的外用药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
酒炒桑枝130g、桂枝60g、夏天无115g、独活95g、羌活220g、桑寄生130g、当归130g、三七80g、桃仁115g、红花95g、川断115g、骨碎补200g、制川乌36g、粉葛根115g、狗骨36g、杜仲115g、牛膝230g、樟脑20g、肉桂46g、薏苡仁260g、木瓜80g、大黄230g、祖司麻115g、片姜黄80g、 威灵仙80g、舒筋草720g、鸡血藤130g、细辛36g、南星80g、土鳖虫80g、蜈蚣46g、乌梢蛇115g、秦艽115g、全虫46g、防风110g、白芷115g、赤芍115g、虎杖115g、粉萆薢120g、乳香(醋制)95g、没药(醋制)95g、附子(制)115g、透骨草115g、延胡索120g、细辛36g、自然铜(醋煅)130g、白屈菜130g。
一种治疗关节疼痛的外用药物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研磨成粉末,过l20目筛,粗粉再加乙醇提取后,浓缩成粉末;
B、将“A”中两种粉末混合均匀后,加入70%的凡士林调均涂于无菌的干纱条上,然后放入药器中,进行高压蒸汽灭菌消毒后,即得外用软膏剂药物;
一种治疗关节疼痛的外用药物及其制备方法,其特征在于,所述使用方法为:将制备好的软膏剂药物外敷于患处,外用无菌纱布块覆盖,每日换药一次, 15天为一个疗程。治疗1~3个疗程,症状逐渐减轻或痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
酒炒桑枝,性味:微苦、平,具有祛风湿、利关节之功效,用于治疗肩臂、关节酸痛麻木;
桂枝,性味:辛、甘、性温,具有散寒解表、温通经脉、通阳化气之功效,用于治疗风寒表证、寒湿痹痛、四肢厥冷、经闭痛经、癥瘕结块、胸痹、心悸、痰饮、小便不利;
夏天无,性味:苦、微辛、温,具有活血通络、行气止痛之功效,用于治疗中风偏瘫、跌扑损伤、风湿性关节炎、坐骨神经痛;
独活,性味:味苦、辛、性微湿,具有祛风胜湿、散寒止痛之功效,用于治疗风寒湿痹、腰膝疼痛、头痛齿痛等症;
羌活,性味:辛苦、温,具有散表寒、祛风湿、利关节之功效,用于治疗感冒风寒、头痛无汗、风寒湿痹、项强筋急、骨节酸疼、风水浮肿、痈疽疮毒等症;
桑寄生,性味:苦、甘、性平,具有补肝肾、强筋骨、祛风湿、安胎之功效,用于治疗腰膝酸痛、筋骨痿弱、肢体偏枯、风湿痹痛、头错目眩、胎动不安、崩漏下血等症;
当归,性味:性温、味甘辛, 具有补血和血、调经止痛、润燥滑肠之功效,用于治疗血虚、面色萎黄、眩晕心悸、血虚、或兼有瘀滞的月经不调、经闭、痛经、虚寒性腹痛、冠心病心绞痛、风湿痹痛、跌打损伤等症;
三七,性味:甘、苦、微温, 具有止血、散瘀、定通、消肿药之功效,适用于刀伤、枪伤及跌扑创伤出血不止,又可治吐血、衄血、便血、尿血、血痢、血崩、经水不止、产后恶血不下、血晕、血痛、目赤通肿、兽咬蛇伤等症;
桃仁,性味:苦甘、平,无毒,具有破血行瘀、润燥滑肠之功效,用于治疗经闭、癥瘕、热病蓄血、风痹、疟疾、跌打损伤、瘀血肿痛、血燥便秘等症;
红花,性味:味辛、性温,具有活血能经、祛瘀止痛之功效,用于治疗经闭、痛经、产后瘀阻腹痛、胞痹心痛症瘕积聚、跌打损伤、关节疼痛、中风偏竣、斑疹等症;
川断,性味:苦、辛、微温,具有补肝肾、强筋骨、续折伤、止崩漏之功效,用于治疗腰膝酸软、风湿痹痛、崩漏、胎漏、跌扑损伤,酒续断多用于风湿痹痛、跌扑损伤,盐续断多用于腰膝酸软;
骨碎补,性味:苦、性温,具有补肾强骨、活血止痛之功效,用于治疗肾虚腰痛、足膝痿弱、耳聋、牙痛、久泄、遗尿、跌打骨折及斑秃等症;
制川乌,性味:味辛、苦、性热,具有祛风除湿、温经止痛之功效,用于治疗用于风寒湿痹、关节冷痛、寒疝作痛及麻醉止痛;
粉葛根,性味:甘、辛、凉,具有解肌退热、生津、透疹、升阳止泻之功效,用于治疗外感发热头痛、项背强痛、口渴、消渴、麻疹不透、热痢、泄泻,高血压和颈项强痛;
狗骨,性味:味甘、咸、性温,具有补肾暗无天日骨、祛风止痛、止血止痢、敛疮生肌之功效,用于治疗内湿关节疼痛、腰腿无力、四肢麻木、崩漏带下、久痢不止、外伤出血、小儿解颅、痈肿疮瘘、冻疮等症;
杜仲,性味:甘、微辛、性温,具有补肝肾、强筋骨、安胎之功效,用于治疗腰脊酸疼、阳痿、尿频、小便余沥、风湿痹痛、胎动不安、习惯性流产等症;
牛膝,性味:苦、酸、性平,具有补肝肾、强筋骨、活血通经、引敌国(火)下行、利尿通淋之功效,用于治疗腰膝酸痛、下肢痿软、血滞经闭、痛经、产后血瘀腹痛、徵瘕、胞衣不下、热淋、血淋、跌打损伤、痈肿恶疮、咽喉肿痛等症;
樟脑,性味:辛、温,具有通窍辟秽、温中止痛、利湿杀虫之功效,用于治疗寒湿吐泻、胃腹疼痛,外用治疥、癣、龋齿作痛;
肉桂,性味:辛、甘、热,具有补火助阳、引火归源、散寒止痛、温经通脉之功效,用于治疗肾阳不足、命门火畏寒肢冷、腰膝酸软、阳痿遗精、小便不利或频数、短气喘促、浮肿尿少诸证、命门火衰、火不归源、戴阳、格阳、及上热下寒、面赤足冷、头晕耳鸣、口舌糜破、脾肾虚寒、脘腹冷痛、食减便溏、肾虚腰痛、寒湿痹痛、寒疝疼痛、宫冷不孕、痛经经闭、产后瘀滞腹痛、阴疽流注、或虚寒痈疡脓成不溃、或溃后不敛等症;
薏苡仁,性味:甘、淡、凉,具有健脾渗湿、除痹止泻、清热排浓之功效,用于治疗水肿、脚气、小便不利、湿痹拘挛、脾虚泄泻、肺痈、肠痈、扁平疣等症;
木瓜,性味:酸、温,具有舒筋活络、和胃化湿之功效,用于治疗风湿痹痛、肢体酸重、筋脉拘挛、吐泻转筋、脚气水肿等症;
大黄,性味:苦、寒,具有泻热通肠、凉血解毒、逐瘀通经之功效,用于治疗实热便秘、积滞腹痛、泻痢不爽、湿热黄疸、血热吐衄、目赤、咽肿、肠痈腹痛、痈肿疔疮、瘀血经闭、跌打损伤,外治水火烫伤,上消化道出血,酒大黄善清上焦血分热毒,用于目赤咽肿、齿龈肿痛,熟大黄泻下力缓、泻火解毒,用于火毒疮疡,大黄炭凉血化瘀止血,用于血热有瘀出血症;
祖司麻,性味:苦、辛、温,有小毒,具有祛风通络、祛瘀止痛之功效,用于治疗头痛、牙痛、风湿关节痛、跌打损伤、胃痛、肝区痛等症;
片姜黄,性味:辛、苦、温,具有破血行气、通经止痛之功效,用于治疗血滞经闭、行经腹痛、胸胁剌痛、风湿痹痛、肩臂疼痛、跌扑损伤;
威灵仙,性味:味辛、咸、微苦、性温,小毒,具有祛风除湿、通络止痛之功效,用于治疗风湿痹痛、肢体、麻木、筋脉拘挛、屈伸不利、脚气肿痛、疟疾、骨哽咽喉、并治痰、饮积聚等症;
舒筋草,性味:微甘、温,具有舒筋活血、祛风湿之功效,用于治疗风湿关节痛、跌打损伤、月经不调;
鸡血藤,性味:味苦、微甘、性温,具有活血舒筋、养血调经之功效,用于治疗手足麻木、肢体瘫痪、风湿痹痛、妇女有经不调、痛经、闭经等症;
细辛,性味:辛、温,具有祛风散寒、通窍止痛、温肺化饮之功效,用于治疗风寒感冒、头痛、牙痛、鼻塞鼻渊、风湿痹痛、痰饮喘咳;
南星,性味:苦、辛、温,有毒,具有燥湿化痰、祛风止痉、散结消肿之功效,用于治疗顽痰咳嗽、风痰眩晕、中风痰壅、口眼歪斜、半身不遂、癫痫、惊风、破伤风,生用外治痈肿,蛇虫咬伤;
土鳖虫,性味:咸、寒,有小毒,具有破瘀血、续筋骨之功效,用于治疗筋骨折伤、瘀血经闭、症瘕痞块;
蜈蚣,性味:味辛、性温,有毒,具有祛风止痉、通络止痛、攻毒散结之功效,用于治疗惊风、癫痫、痉挛抽搐、中风口、破伤风、风湿顽痹、偏正头痛、毒蛇咬伤、疮疡、瘰疬等症;
乌梢蛇,性味:甘、平,具有祛风、通络、止痉之功效,用于治疗风湿顽痹、麻木拘挛、中风、口眼歪斜、半身不遂、抽搐痉挛、破伤风、麻风疥癣、瘰疬恶疮等症;
秦艽,性味:苦、辛、微寒,具有祛风湿、舒筋络、清虚热、利湿退黄之功效,用于治疗风湿痹通痛、筋骨拘挛、手足不遂、骨蒸潮热、小儿疳热、湿热黄疸;
全虫,性味:辛、平;有毒,具有息风镇痉、攻毒散结、通络止痛之功效,用于治疗小儿惊风、抽搐痉挛、中风口歪、半身不遂、破伤风、风湿顽痹、偏正头痛、疮疡、瘰疬等症;
防风,性味:味辛、甘、性微温,具有祛风解表、胜湿止痛、解痉、止痒之功效,用于治疗外感风寒、头痛身痛、风湿痹痛、骨节酸痛、腹痛泄泻、肠风下血、破伤风、风疹瘙痒、疮疡初起等症;
白芷,性味:性温、味辛、气芳香、微苦,具有祛风湿、活血排脓、生肌止痛的功效,用于头痛、牙痛、鼻渊、肠风痔漏、赤白带下、痈疽疮疡、皮肤瘙痒;
赤芍,性味:苦、微寒,具有清热凉血、活血祛瘀之功效,用于治疗温毒发斑、吐血衄血、肠风下血、目赤肿痛、痈肿疮疡、闭经、痛经、崩带淋浊、瘀滞胁痛、疝瘕积聚、跌扑损伤等症;
虎杖,性味:微苦、微寒,具有祛风利湿、散瘀定痛、止咳化痰之功效,用于治疗关节痹痛、湿热黄疸、经闭、症瘕、水火烫伤、跌扑损伤、痈肿疮毒、咳嗽痰多;
粉萆薢,性味:苦、平,具有利湿去浊、祛风除痹之功效,用于治疗膏淋、白浊、白带过多、风湿痹痛、关节不利、腰膝疼痛;
乳香(醋制),性味:味辛、苦、微温,具有活血行气;通经止痛;消肿生肌之功效,用于治疗心腹疼痛、风湿痹痛、经闭痛经、跌打瘀痛、痈疽肿毒、肠痈、疮溃不敛等症;
没药(醋制),性味:苦、平,具有活血止痛、消肿生肌之功效,用于治疗胸腹瘀痛、痛经、经闭、症瘕、跌打损伤、痈肿疮疡、肠痈、目赤肿痛等症;
附子(制),性味:辛甘、热,有毒,具有回阳救逆、补火助阳、散寒除湿之功效,用于治疗阴盛格阳、大汗亡阳、吐利厥逆、心腹冷痛、脾泄冷痢、脚气水肿、小儿慢惊、风寒湿痹、踒躄拘挛、阳萎、宫冷阴、疽疮漏及一切沉寒痼冷之疾;
透骨草,性味:辛、性温,具有祛风除湿、舒筋活血、散瘀消肿、解毒目痛之功效,用于治疗风湿痹痛、筋骨挛缩、寒湿脚气、腰部扭伤、瘫痪、闭经、阴囊湿疹、疮疖肿毒等症;
延胡索,性味:辛苦、温,具有活血、散瘀、理气、止痛之功效,用于治疗心腹腰膝诸痛、月经不调、症瘕、崩中、产后血晕、恶露不尽、跌打损伤等症;
细辛,性味:辛、温,具有祛风散寒、通窍止痛、温肺化饮之功效,用于治疗风寒感冒、头痛、牙痛、鼻塞鼻渊、风湿痹痛、痰饮喘咳;
自然铜(醋煅),性味:辛、苦、平,无毒,具有散瘀止痛、接骨续筋之功效,用于治疗跌打损伤、筋断骨折、瘀滞肿痛等症;
白屈菜,性味:苦、凉,有毒,具有清热解毒、止痛、止咳之功效,用于治疗胃炎、胃溃疡、腹痛、肠炎、痢疾、黄疸、慢性气管炎、百日咳,外用治水田皮炎、毒虫咬伤等症。
本发明药物是基于中医治疗关节疼痛的原则,从依据关节疼痛的病理机制及药理作用认为:就关节疼痛,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的效果。
具体实施方式
本发明就是针对上述关节疼痛的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个很好的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种治疗关节疼痛的外用药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
酒炒桑枝130g、桂枝60g、夏天无115g、独活95g、羌活220g、桑寄生130g、当归130g、三七80g、桃仁115g、红花95g、川断115g、骨碎补200g、制川乌36g、粉葛根115g、狗骨36g、杜仲115g、牛膝230g、樟脑20g、肉桂46g、薏苡仁260g、木瓜80g、大黄230g、祖司麻115g、片姜黄80g、 威灵仙80g、舒筋草720g、鸡血藤130g、细辛36g、南星80g、土鳖虫80g、蜈蚣46g、乌梢蛇115g、秦艽115g、全虫46g、防风110g、白芷115g、赤芍115g、虎杖115g、粉萆薢120g、乳香(醋制)95g、没药(醋制)95g、附子(制)115g、透骨草115g、延胡索120g、细辛36g、自然铜(醋煅)130g、白屈菜130g。
实施例2:
一种治疗关节疼痛的外用药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
酒炒桑枝150g、桂枝70g、夏天无130g、独活105g、羌活250g、桑寄生150g、当归150g、三七90g、桃仁130g、红花105g、川断130g、骨碎补220g、制川乌42g、粉葛根130g、狗骨42g、杜仲130g、牛膝260g、樟脑22g、肉桂52g、薏苡仁320g、木瓜90g、大黄260g、祖司麻130g、片姜黄90g、 威灵仙90g、舒筋草850g、鸡血藤150g、细辛42g、南星90g、土鳖虫90g、蜈蚣52g、乌梢蛇130g、秦艽130g、全虫52g、防风115g、白芷130g、赤芍130g、虎杖130g、粉萆薢140g、乳香(醋制)105g、没药(醋制)105g、附子(制)130g、透骨草130g、延胡索140g、细辛42g、自然铜(醋煅)150g、白屈菜150g。
实施例3:
一种治疗关节疼痛的外用药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
酒炒桑枝180g、桂枝80g、夏天无150g、独活120g、羌活280g、桑寄生180g、当归180g、三七100g、桃仁160g、红花120g、川断160g、骨碎补250g、制川乌50g、粉葛根160g、狗骨50g、杜仲150g、牛膝300g、樟脑25g、肉桂60g、薏苡仁350g、木瓜100g、大黄300g、祖司麻150g、片姜黄100g、 威灵仙100g、舒筋草1000g、鸡血藤180g、细辛50g、南星100g、土鳖虫100g、蜈蚣60g、乌梢蛇150g、秦艽150g、全虫70g、防风160g、白芷180g、赤芍180g、虎杖160g、粉萆薢160g、乳香(醋制)120g、没药(醋制)120g、附子(制)150g、透骨草160g、延胡索160g、细辛50g、自然铜(醋煅)180g、白屈菜180g。
典型病例
经临床诊断治疗关节疼痛患者共1300例,年龄为63岁以上的895例,只有675例为63岁以下。1300例患者中痊愈的820例,有效的376例,无效的104例。总有效率达92%。

Claims (3)

1.一种治疗关节疼痛的外用药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
酒炒桑枝100~180g、桂枝20~80g、夏天无60~150g、独活30~120g、羌活100~280g、桑寄生100~180g、当归80~180g、三七30~100g、桃仁80~160g、红花30~120g、川断90~160g、骨碎补100~250g、制川乌20~50g、粉葛根90~160g、狗骨20~50g、杜仲60~150g、牛膝150~300g、樟脑10~25g、肉桂20~60g、薏苡仁90~350g、木瓜50~100g、大黄30~300g、祖司麻50~150g、片姜黄30~100g、 威灵仙60~100g、舒筋草250~1000g、鸡血藤100~180g、细辛10~50g、南星30~100g、土鳖虫30~100g、蜈蚣20~60g、乌梢蛇90~150g、秦艽50~150g、全虫30~70g、防风80~160g、白芷50~180g、赤芍60~180g、虎杖90~160g、粉萆薢90~160g、乳香(醋制)30~120g、没药(醋制)30~120g、附子(制)50~150g、透骨草90~160g、延胡索80~160g、细辛10~50g、自然铜(醋煅)50~180g、白屈菜50~180g。
2.根据权利要求1所述的治疗关节疼痛的外用药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
酒炒桑枝115~150g、桂枝26~70g、夏天无70~130g、独活36~105g、羌活115~250g、桑寄生115~150g、当归90~150g、三七36~90g、桃仁90~130g、红花36~105g、川断100~130g、骨碎补115~220g、制川乌26~42g、粉葛根100~130g、狗骨26~42g、杜仲70~130g、牛膝180~260g、樟脑11~22g、肉桂26~52g、薏苡仁100~320g、木瓜58~90g、大黄38~260g、祖司麻58~130g、片姜黄36~90g、 威灵仙70~90g、舒筋草220~850g、鸡血藤115~150g、细辛11~42g、南星38~90g、土鳖虫36~90g、蜈蚣26~52g、乌梢蛇100~130g、秦艽58~130g、全虫42~52g、防风100~115g、白芷68~130g、赤芍80~130g、虎杖100~130g、粉萆薢100~140g、乳香(醋制)36~105g、没药(醋制)36~105g、附子(制)58~130g、透骨草100~130g、延胡索90~140g、细辛11~42g、自然铜(醋煅)58~150g、白屈菜58~150g。
3.根据权利要求1至2所述的治疗关节疼痛的外用药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
酒炒桑枝130g、桂枝60g、夏天无115g、独活95g、羌活220g、桑寄生130g、当归130g、三七80g、桃仁115g、红花95g、川断115g、骨碎补200g、制川乌36g、粉葛根115g、狗骨36g、杜仲115g、牛膝230g、樟脑20g、肉桂46g、薏苡仁260g、木瓜80g、大黄230g、祖司麻115g、片姜黄80g、 威灵仙80g、舒筋草720g、鸡血藤130g、细辛36g、南星80g、土鳖虫80g、蜈蚣46g、乌梢蛇115g、秦艽115g、全虫46g、防风110g、白芷115g、赤芍115g、虎杖115g、粉萆薢120g、乳香(醋制)95g、没药(醋制)95g、附子(制)115g、透骨草115g、延胡索120g、细辛36g、自然铜(醋煅)130g、白屈菜130g。
CN201710802288.8A 2017-09-07 2017-09-07 一种治疗关节疼痛的外用药物及其制备方法 Withdrawn CN107469007A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710802288.8A CN107469007A (zh) 2017-09-07 2017-09-07 一种治疗关节疼痛的外用药物及其制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710802288.8A CN107469007A (zh) 2017-09-07 2017-09-07 一种治疗关节疼痛的外用药物及其制备方法

Publications (1)

Publication Number Publication Date
CN107469007A true CN107469007A (zh) 2017-12-15

Family

ID=60583530

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710802288.8A Withdrawn CN107469007A (zh) 2017-09-07 2017-09-07 一种治疗关节疼痛的外用药物及其制备方法

Country Status (1)

Country Link
CN (1) CN107469007A (zh)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108721586A (zh) * 2018-07-19 2018-11-02 肖波 一种拔罐用组合药物及其拔罐
CN109602794A (zh) * 2019-03-01 2019-04-12 吉林省中医药科学院(吉林省中医药科学院第临床医院) 一种治疗骨关节炎的中药组合物及制备方法和用途
CN110302295A (zh) * 2019-08-14 2019-10-08 王东来 一种治疗身体关节疼痛的中药配方及其制备方法
CN113304239A (zh) * 2021-05-29 2021-08-27 湖北理工学院 一种用于关节疼痛的中药贴剂制备方法
CN115837061A (zh) * 2022-12-02 2023-03-24 河南省人民医院 用于缓解疼痛的中药制剂及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104147502A (zh) * 2013-05-15 2014-11-19 董福华 一种治疗关节疼痛的中药组合物及其制备方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104147502A (zh) * 2013-05-15 2014-11-19 董福华 一种治疗关节疼痛的中药组合物及其制备方法

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108721586A (zh) * 2018-07-19 2018-11-02 肖波 一种拔罐用组合药物及其拔罐
CN109602794A (zh) * 2019-03-01 2019-04-12 吉林省中医药科学院(吉林省中医药科学院第临床医院) 一种治疗骨关节炎的中药组合物及制备方法和用途
CN110302295A (zh) * 2019-08-14 2019-10-08 王东来 一种治疗身体关节疼痛的中药配方及其制备方法
CN113304239A (zh) * 2021-05-29 2021-08-27 湖北理工学院 一种用于关节疼痛的中药贴剂制备方法
CN115837061A (zh) * 2022-12-02 2023-03-24 河南省人民医院 用于缓解疼痛的中药制剂及其应用
CN115837061B (zh) * 2022-12-02 2023-12-19 河南省人民医院 用于缓解疼痛的中药制剂及其应用

Similar Documents

Publication Publication Date Title
CN107469007A (zh) 一种治疗关节疼痛的外用药物及其制备方法
CN102552759B (zh) 治疗骨折后引起的肿胀及疼痛的中药组合物
CN108619478A (zh) 一种治疗风湿骨痛的中药配方
CN107596300A (zh) 一种用于治疗颈椎病及骨关节疾病的新型中药组合物
CN106729225A (zh) 一种活络止痛贴膏及其制备方法
CN107537015A (zh) 一种治疗风湿寒热所致痹病的丸剂药物及制备方法
CN105012430A (zh) 一种治疗坐骨神经病痛的药物及其制备方法
CN107596084A (zh) 一种治疗类风湿性关节炎的内服药物及其制备方法
CN106039240A (zh) 一种治疗乳腺纤维瘤的中药组合物
CN104958520A (zh) 一种治疗骨性关节炎的中药
CN104800610A (zh) 一种治疗帕金森病的中药制剂及其制备方法
CN109908245A (zh) 一种用于治疗颈肩腰腿痛病的中药组合物
CN107638465A (zh) 一种治疗关节疼痛的中药组合物及其制备方法
CN107335019A (zh) 一种用于治疗正、偏头痛的丸剂药物及其制备方法
CN107349313A (zh) 一种治疗颈椎、腰椎病的中药配方
CN106853240A (zh) 一种可有效治疗骨病的外用汤剂药物及其制备方法
CN104547153A (zh) 一种治疗脉络瘀阻型痿证的中药组合物
CN105362554A (zh) 一种治疗肝肾亏损型小儿麻痹症的中药
CN103768463B (zh) 一种治疗痹症的中药汤剂
CN103798720A (zh) 一种杜仲强筋健骨火锅料及生产方法
CN110101819A (zh) 一种治疗急慢性关节炎的外用中药组合物、粉剂及其应用
CN107569653A (zh) 一种治疗老年骨关节炎的汤剂药物及其制备方法
CN107468990A (zh) 一种用于舒筋活络和止痛的中药组合物及其制备方法
CN107596314A (zh) 一种治疗风湿寒热所致痹病的丸剂药物及制备方法
CN109954042A (zh) 一种琥珀膏及其制备方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication

Application publication date: 20171215

WW01 Invention patent application withdrawn after publication