CN107456386A - The acupuncture needle of a kind of anti-inflammatory analgesic and can packing type field operation quick needle insertion device - Google Patents

The acupuncture needle of a kind of anti-inflammatory analgesic and can packing type field operation quick needle insertion device Download PDF

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Publication number
CN107456386A
CN107456386A CN201710531558.6A CN201710531558A CN107456386A CN 107456386 A CN107456386 A CN 107456386A CN 201710531558 A CN201710531558 A CN 201710531558A CN 107456386 A CN107456386 A CN 107456386A
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CN
China
Prior art keywords
acupuncture needle
needle
acupuncture
parts
housing
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Pending
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CN201710531558.6A
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Chinese (zh)
Inventor
顾伟
舒适
田思楠
岳新雨
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Shanghai Changhai Hospital
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Shanghai Changhai Hospital
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Priority to CN201710531558.6A priority Critical patent/CN107456386A/en
Publication of CN107456386A publication Critical patent/CN107456386A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H39/00Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
    • A61H39/08Devices for applying needles to such points, i.e. for acupuncture ; Acupuncture needles or accessories therefor
    • A61H39/086Acupuncture needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/65Amphibians, e.g. toads, frogs, salamanders or newts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/12Driving means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/216Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402Anaestetics, analgesics, e.g. lidocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41Anti-inflammatory agents, e.g. NSAIDs

Abstract

The present invention relates to a kind of acupuncture needle of anti-inflammatory analgesic and can packing type field operation quick needle insertion device, the acupuncture needle includes acupuncture needle body and the medication coat coated in acupuncture needle body surface, and the medication coat is made up of the bulk drug of parts by weight as described below:2 parts of the red sage root, 1 part of safflower, 2 parts of chrysanthemum indicum, 3 parts of the dried venom of toads, 2 parts of lidocaine, 1 part of Vitwas E.The present invention be coated with medication coat in acupuncture wire surface, acupuncture is needled into wound during use, the medication coat coated in acupuncture and moxibustion needle body surface melts in wound, and decoction, which is loaded into wound, to be absorbed, performance therapeutic efficiency.The medication coat of the present invention has significant anti-inflammatory analgesic effect, onset time is short, analgesic effect is notable, with can packing type field operation quick needle insertion device with the use of the constant pain after acupuncture is needled into can be significantly reduced, the aseptic of strong instrumentation simultaneously, in the case that certainly General Medical Officer sergeant reaches sterile working in wartime under field condition the problem of rapid and handy application.

Description

The acupuncture needle of a kind of anti-inflammatory analgesic and can packing type field operation quick needle insertion device
Technical field
The present invention relates to pharmaceutical technology field, specifically, be a kind of anti-inflammatory analgesic acupuncture needle and can packing type field operation With quick needle insertion device.
Background technology
Present war has multidimensional, wide front, great depth, comprehensive Multidimensional Warfare feature, and army is frequently motor-driven, the wounded In the irregular distribution of comprehensive and space-time, it is necessary to which the wounded continuously given treatment in field first aid and way increase.The wounded's hinders class, hinders type Increase, condition of the injury traumatic part is increasingly complex, and wherein injury disease is most common, accounts for 37.18%, muscle skeleton connective tissue disease (12.18%), skin disease and hypodermis disease (5.77%).But due to my army's field medical equipment weak foundation, develop Walk it is later, for modern war wounded change in time and space and the new condition of the injury, hinder class feature in terms of, also exist in rescue equipment development Deficiency, the needs of future war far can not be adapted to.Acupuncture is notable in clinical therapeutic efficacy, for a variety of common Injuries In Military Trainings All there is unique advantage, under new military situation, the Chinese Traditional Medicine such as acupuncture is more approved by general headquarters.U.S. army is at health support field In world lead level, wartime acupuncture has tremendous development in U.S. army, and U.S. can not still be met by training out hundreds wartime acupuncture practitioner Army's demand, U.S. army find that this medical mode convenient, rapid-action, that side effect is low of acupuncture is more suitable for military combat use.But pass System acupuncture is limited by technical skill, and General Medical Officer can not operate.Pass through the advantage and disadvantage of all kinds of inserting needle modes of com-parison and analysis, it is desirable to logical Cross to research and develop a kind of new Portable field army acupuncture-moxibustion therapy needling device and solve General Medical Officer sergeant under field condition and reach sterile behaviour in wartime The problem of rapid and handy is applied in the case of work.There is the practicality promoted on a large scale and low cost, reusable simultaneously Economy.
Pain is that body receives caused a kind of aversion response after noxious stimulation, is often accompanied by frightened, nervous Etc. emotional activity.The wadding that pain, in sensorial pain and the not Anwai in mood, can also result in physiological function except reacting is random, Cause insomnia, or even can induce and suffer a shock and threat to life.Current acupuncture needle can only carry out acupuncture of a point moxibustion mostly, can not Medicine is set effectively to reach acupuncture point deep layer, so as to medicine be made to give full play to drug effect.Chinese patent 2015103240302 discloses A kind of acupuncture needle with medicine film and preparation method thereof, it includes the needle body of metal base, the needle body surface from the inside to the outside also according to Secondary to be provided with graft polymer layer and medicine film layer, the acupuncture needle improves therapeutic effect of acupuncture and moxibustion.Chinese patent 2003201124013 is public A kind of acupuncture needle for carrying medicine has been opened, the needle body outer surface coating medicine layer for the acupuncture needle that it is made up of needle body and needle handle is formed, The load medicine puncture needle is effective in cure fast, can improve therapeutic effect of acupuncture and moxibustion, extends application of acupuncture scope, and do not have to row in acupuncture Pin, keenly feel the advantages that smaller.But in the prior art, on anti-inflammatory analgesic of the present invention acupuncture needle and can packing type field operation with fast Fast needle inserter, it yet there are no report.
The content of the invention
First purpose of the present invention is to be directed to deficiency of the prior art, there is provided a kind of drug regimen of anti-inflammatory analgesic Thing.
Second object of the present invention is to be directed to deficiency of the prior art, there is provided a kind of pin with anti-inflammatory analgesic effect Acupuncture needle.
Third object of the present invention is to be directed to deficiency of the prior art, there is provided a kind of comprising acupuncture needle as described above Can packing type field operation quick needle insertion device.
To realize above-mentioned first purpose, the present invention adopts the technical scheme that:
A kind of pharmaceutical composition of anti-inflammatory analgesic, described pharmaceutical composition are made up of the bulk drug of parts by weight as described below: 2 parts of the red sage root, 1 part of safflower, 2 parts of chrysanthemum indicum, 3 parts of the dried venom of toads, 2 parts of lidocaine, 1 part of Vitwas E.
To realize above-mentioned second purpose, the present invention adopts the technical scheme that:
A kind of acupuncture needle with anti-inflammatory analgesic effect, including acupuncture needle body and the medicine coated in acupuncture needle body surface Thing coating, the medication coat are made up of pharmaceutical composition as described above.
Further, the preparation method of the medication coat is as follows:
(1) 2 parts of the Chinese medicine material red sage root, 1 part of safflower, 2 parts of chrysanthemum indicum, 3 parts of the dried venom of toads, 8 times of water of dosing material total amount, backflow are taken Twice, 1 hour every time, decoction merged, filtration for extraction, is concentrated into liquor strength and reaches 1.15g/ml, adds ethanol to alcohol content For 70%, stand overnight, centrifuge, take supernatant, concentrate, vacuum drying, obtain extract;
(2) extract is well mixed with 2 parts of lidocaine, 1 part of Vitwas E, adds 2 parts of polyethylene glycol and second 5 parts of alcohol, 30-40 DEG C is heated to after mixing, constant temperature stirs to obtain coating solution;
(3) coating solution is added to coating machine, the Vltrasonic device power for adjusting the coating machine is 5-50W, by mist Coating solution after change is sprayed on the acupuncture needle body surface, both.
To realize above-mentioned 3rd purpose, the present invention adopts the technical scheme that:
One kind can packing type field operation quick needle insertion device, the needle inserter include housing (1), acupuncture needle storage part (2), ejection Broken skin portion (3), promotion part (4), the acupuncture needle storage part (2) include acupuncture needle cylinder (5), dividing plate (6), and the acupuncture needle cylinder (5) is circle Cylindricality, acupuncture needle cylinder (5) is interior provided with some acupuncture needle holes (7) for being used to store acupuncture needle, and acupuncture as described above is provided with acupuncture needle hole (7) Pin (32), the dividing plate (6) are provided with perforation (8), acupuncture needle cylinder (5) and the be hinged fixation of dividing plate (6), and acupuncture needle cylinder (5) can be around cylinder Axis rotation, during rotation difference acupuncture needle hole (7) with perforate (8) it is corresponding;
The housing (1) is fixedly connected with dividing plate (6), and housing (1) is provided with elastic force lockhole (19) and hits lockhole (22); It is described ejection broken skin portion (3) include push rod (9), cut somebody's hair (10), resilient clip (11), by pressing spring (12), back-moving spring (13), Spring dead plate (14), hit platform (15), hit clamp (16), inserting needle working chamber (17);The inserting needle working chamber (17) with every Perforation (8) on plate (6) is corresponding, and inserting needle working chamber is arranged on the inner surface of housing (1);The push rod (9) and acupuncture needle cylinder (5) and Dividing plate (6) is slidably connected, and one end of push rod (9) passes from acupuncture needle cylinder (5) end face, the other end with cut somebody's hair (10) be fixedly connected;Institute State cut somebody's hair (10) be provided with resilient clip (11), the resilient clip (11) is flexible arm structure, and its one end is with pushing away Head (10) is fixedly connected, and the other end is mobilizable protrusion button (18), and protrusion button (18) matches simultaneously with elastic force lockhole (19) It can be passed from elastic force lockhole (19), when pressing push rod (9), protrusion button (18) slides into lock from the inner surface of housing (1) Hole (19), locking is passed from elastic force lockhole (19) in the presence of elastic force;It is described cut somebody's hair (10) be provided with by pressing spring (12), Back-moving spring (13), the back-moving spring (13) are connected with being fixed on the spring dead plate (14) of housing (1) inner surface, and pressing pushes away Bar (9) makes to cut somebody's hair (10) produces reseting elasticity between spring dead plate (14), described by pressing spring (12) and shock platform (15) Connection, it is described shock platform (15) be divided into impact head (20) and hit clamp (16) two parts, it is described shock clamp (16) be with The arm structure of elasticity, its one end are fixedly connected with hitting platform (15), and the other end is mobilizable shock button (21), and shock is pressed Key (21) matches with shock lockhole (22) and can pass locking from lockhole (22) is hit, when protrusion button (18) is in elastic force lockhole (19) when locking is passed in, cutting somebody's hair (10) and hitting produces elastic force between platform (15), and button (21) is hit in now pressing, and shock is pressed Key slides to housing (1) inner surface from lockhole (22) is hit, and hits platform (15) and unlocks and in the elastic force work by pressing spring (12) With lower shock stretches push rod (24);
The promotion part (4) includes puncture working chamber (23) and stretches push rod (24), and the puncture working chamber (23) is set In the inner surface of housing (1) and corresponding with inserting needle working chamber (17), the stretches push rod (24) includes the body of rod (25) and is fixed on Baffle (26), impact head baffle plate (27) on the body of rod (25), acupuncture needle baffle plate (28), the acupuncture needle baffle plate (28), which is set, to be punctured In working chamber (23), the impact head baffle plate (27) is arranged on the stage casing of the body of rod (25) and, the shell corresponding with impact head (20) Body (1) is provided with the housing elongated slot (29) along acupuncture needle cylinder (5) axis direction, the inserting needle working chamber (17), puncture working chamber (23) the cavity elongated slot (30) along acupuncture needle cylinder (5) axis direction is provided with, the housing elongated slot (29) is provided with scale marker (31), the head end of the body of rod (25) passes from housing elongated slot (29), and the tail end of the body of rod (25) passes through simultaneously from cavity elongated slot (30) Fixed with the body of rod (25), baffle (26) is arranged between impact head baffle plate (27) and housing elongated slot (29), the puncture work The cavity cross-sectional area for making chamber (23) is less than inserting needle working chamber (17) cavity cross-sectional area, the shape of acupuncture needle baffle plate (28) and puncture The cross-sections match of working chamber (23), acupuncture needle baffle plate (28) can slide up and down along inserting needle working chamber (17), puncture working chamber (23).
Further, the quantity of the acupuncture needle hole (7) is 5-20, and acupuncture needle hole (7) are uniform around acupuncture needle cylinder (5) central axis Distribution.
Further, housing (1) surface is additionally provided with stretchable specification (33);The stretchable specification (33) One end is fixed with housing (1), and the other end is stretch rod (34).
Further, the stretchable specification (33) is made up of flexible paper, and specification natural shrinking is crimped onto housing (1) surface, stretch rod (34) can be embedded in the groove on housing (1) surface that stretchable specification (33) is fixed.
The invention has the advantages that:
1st, the invention provides a kind of acupuncture needle with anti-inflammatory analgesic effect, by acupuncture needle body and coated in acupuncture needle The medication coat composition of body surface, the medicine is by 2 parts of the red sage root, 1 part of safflower, 2 parts of chrysanthemum indicum, 3 parts of the dried venom of toads, lidocaine 2 1 part of part, Vitwas E composition, polyethylene glycol and ethanol are added by above-mentioned Chinese medical extract, atomization by painting in coating machine Layer solution spraying is in acupuncture needle body surface.Acupuncture is needled into wound during use, the medicine coated in acupuncture and moxibustion needle body surface applies Layer melts in wound, and decoction, which is loaded into wound, to be absorbed, and further reaches therapeutic efficiency.
2nd, the present invention is coated with medication coat on acupuncture needle needle body surface, and the medication coat has significant anti-inflammatory analgesic work( Effect, and onset time is short, and analgesic effect is notable, with can packing type field operation quick needle insertion device with the use of acupuncture needle can be significantly reduced Constant pain after piercing.
3rd, it is of the invention can packing type field operation quick needle insertion device by the sterilization inserting needle process simplicity of complexity, make inserting needle process More standardize, can well observe without mattress operating technology, reduce hospital-acquired infection, solve General Medical Officer sergeant's field condition The problem of lower application acupuncture technique treatment wounded.
4th, the present invention can packing type field operation quick needle insertion device by elastic force, pin is sprung into acupuncture point, it is fast to enter needle speed.Acupoint selection is accurate Really, it is not easy to bend pin, can mitigates into pain during skin, if skilled operation, gain the essentials, can reach painless.
5th, the present invention can packing type field operation quick needle insertion utensil have safety, small volume, good appearance is easy to carry, warp Ji is practical, is easy to learn and use, easy to operate, is easily mastered, few side effects.
6th, the present invention increases storage device and acupuncture needle propulsion plant to solve the problems such as continuous acupuncture, regulation depth of needle, Strengthen the aseptic of instrumentation simultaneously, ensure that needle body is not polluted in sterile working, solve General Medical Officer sergeant under field condition and exist Wartime reaches the problem of rapid and handy is applied in the case of sterile working.
7th, each needle inserter of the present invention can accommodate 5-20 root acupuncture needles, quickly can wait to penetrate by acupuncture needle action after each acupuncture State, simplifies operating process, and the puncture speed and strength of acupuncture needle is not dependent on personal experience and the feel of operator, depth of needle It is easily controlled, General Medical Officer sergeant can be used in field condition according to simple prompting explanation.
8th, the present invention is additionally provided with stretchable specification in surface of shell, and specification natural shrinking is crimped onto surface of shell, The operation instruction of the present invention is recorded on its surface, and stretch rod, which can be embedded in the groove of surface of shell, fixes stretchable explanation 4, for the first time User can be used according to the record of specification.
Brief description of the drawings
Accompanying drawing 1 be the present invention can packing type field operation quick needle insertion device structural representation (one).
Accompanying drawing 2 be the present invention can packing type field operation quick needle insertion device structural representation (two).
Accompanying drawing 3 be the present invention can packing type field operation quick needle insertion device structural representation (three).
Accompanying drawing 4 be the present invention can packing type field operation quick needle insertion device structural representation (four).
Accompanying drawing 5 be the present invention can packing type field operation quick needle insertion device structural representation (five).
Accompanying drawing 6 is the structural representation of promotion part.
Accompanying drawing 7 is promotion part cross-sectional view (one).
Accompanying drawing 8 is promotion part cross-sectional view (two).
Accompanying drawing 9 is stretchable specification structure schematic diagram.
Embodiment
The invention will be further elucidated with reference to specific embodiments.It should be understood that these embodiments are merely to illustrate this hair Bright rather than limitation the scope of the present invention.In addition, it is to be understood that after the content of the invention recorded has been read, art technology Personnel can make various changes or modifications to the present invention, and these equivalent form of values equally fall within the application appended claims and limited Fixed scope.
The pharmaceutical composition of the anti-inflammatory analgesic of embodiment 1
A kind of pharmaceutical composition of anti-inflammatory analgesic, described pharmaceutical composition are made up of the bulk drug of parts by weight as described below: 2 parts of the red sage root, 1 part of safflower, 2 parts of chrysanthemum indicum, 3 parts of the dried venom of toads, 2 parts of lidocaine, 1 part of Vitwas E.
Embodiment 2 has the acupuncture needle of anti-inflammatory analgesic effect
A kind of acupuncture needle with anti-inflammatory analgesic effect, including acupuncture needle body and the medicine for overlaying on acupuncture needle body surface Coating, the medication coat are made up of the bulk drug of parts by weight as described below:2 parts of the red sage root, 1 part of safflower, 2 parts of chrysanthemum indicum, the dried venom of toads 3 Part, 2 parts of lidocaine, 1 part of Vitwas E.
The preparation method of the acupuncture needle is as follows:
(1) 2 parts of the Chinese medicine material red sage root, 1 part of safflower, 2 parts of chrysanthemum indicum, 3 parts of the dried venom of toads, 8 times of water of dosing material total amount, backflow are taken Twice, 1 hour every time, decoction merged, filtration for extraction, is concentrated into liquor strength and reaches 1.15g/ml, adds ethanol to alcohol content For 70%, stand overnight, centrifuge, take supernatant, concentrate, vacuum drying, obtain extract;
(2) extract is well mixed with 2 parts of lidocaine, 1 part of Vitwas E, adds 2 parts of polyethylene glycol and second 5 parts of alcohol, 30-40 DEG C is heated to after mixing, constant temperature stirs to obtain coating solution;
(3) coating solution is added to coating machine, the Vltrasonic device power for adjusting the coating machine is 5-50W, by mist Coating solution after change is sprayed on described this body surface of acupuncture needle.
Analgesic activity of 3 pharmaceutical composition of the present invention of embodiment to hot plate method induced pain mouse
Female mice is taken, weight (20 ± 2) g, is put into 50 DEG C of hot plate water-baths, is referred to using licking metapedes as pain reaction Mark, prediction mouse pain threshold between 5-40s for qualified mouse, after administration more than 60s person in terms of 60s.Logical threshold is qualified Mouse be randomly divided into 9 groups, every group 20.1st group is isodose matrix (polyethylene glycol and ethanol) control group;2nd group is Positive control medicine aspirin group, ig 0.2g/kg;3rd group is experimental group 1, analgesic 0.5g/kg;4th group is experiment Group 2, analgesic 0.5g/kg;5th group is experimental group 3, analgesic 0.5g/kg;6th group is experimental group 4, analgesic 0.5g/kg;7th group is experimental group 5, analgesic 0.5g/kg;8th group is experimental group 6, analgesic 0.5g/kg;9th group is Experimental group 7, analgesic 0.5g/kg.Medicaments uniformity is coated on mouse tail, coating area is 1-2cm2, with not sensitization glue Cloth covering is fixed, and 1h, 2h, 4h, 8h, 12h, 24h determine pain threshold respectively after last dose.
The process for preparing medicine of experimental group 1 is as follows:
(1) 2 parts of the red sage root, 1 part of safflower, 2 parts of chrysanthemum indicum, 3 parts of the dried venom of toads, 2 parts of lidocaine, 1 part of Vitwas E;
(2) the Chinese medicine material red sage root, safflower, chrysanthemum indicum, the dried venom of toads, 8 times of water of dosing material total amount, refluxing extraction are taken by weight Twice, every time 1 hour, decoction merged, filtration, is concentrated into liquor strength and reaches 1.15g/ml, adds ethanol to alcohol content and is 70%, stand overnight, centrifuge, take supernatant, concentrate, vacuum drying, obtain extract;
(3) extract is well mixed with lidocaine, Vitwas E, adds 5 parts of 2 parts of polyethylene glycol and ethanol, 30-40 DEG C is heated to after mixing, constant temperature stirring, was both obtained.
The process for preparing medicine of experimental group 2 is as follows:
(1) 3 parts of the red sage root, 1 part of safflower, 1 part of chrysanthemum indicum, 1 part of the dried venom of toads, 1 part of lidocaine, 1 part of Vitwas E;
(2) the Chinese medicine material red sage root, safflower, chrysanthemum indicum, the dried venom of toads, 8 times of water of dosing material total amount, refluxing extraction are taken by weight Twice, every time 1 hour, decoction merged, filtration, is concentrated into liquor strength and reaches 1.15g/ml, adds ethanol to alcohol content and is 70%, stand overnight, centrifuge, take supernatant, concentrate, vacuum drying, obtain extract;
(3) extract is well mixed with lidocaine, Vitwas E, adds 5 parts of 2 parts of polyethylene glycol and ethanol, 30-40 DEG C is heated to after mixing, constant temperature stirring, was both obtained.
The process for preparing medicine of experimental group 3 is as follows:
(1) 1 part of the red sage root, 1 part of safflower, 1 part of chrysanthemum indicum, 4 parts of the dried venom of toads, 1 part of lidocaine, 1 part of Vitwas E;
(2) the Chinese medicine material red sage root, safflower, chrysanthemum indicum, the dried venom of toads, 8 times of water of dosing material total amount, refluxing extraction are taken by weight Twice, every time 1 hour, decoction merged, filtration, is concentrated into liquor strength and reaches 1.15g/ml, adds ethanol to alcohol content and is 70%, stand overnight, centrifuge, take supernatant, concentrate, vacuum drying, obtain extract;
(3) extract is well mixed with lidocaine, Vitwas E, adds 5 parts of 2 parts of polyethylene glycol and ethanol, 30-40 DEG C is heated to after mixing, constant temperature stirring, was both obtained.
The process for preparing medicine of experimental group 4 is as follows:
(1) 1 part of the red sage root, 3 parts of safflower, 1 part of chrysanthemum indicum, 1 part of the dried venom of toads, 1 part of lidocaine, 1 part of Vitwas E;
(2) the Chinese medicine material red sage root, safflower, chrysanthemum indicum, the dried venom of toads, 8 times of water of dosing material total amount, refluxing extraction are taken by weight Twice, every time 1 hour, decoction merged, filtration, is concentrated into liquor strength and reaches 1.15g/ml, adds ethanol to alcohol content and is 70%, stand overnight, centrifuge, take supernatant, concentrate, vacuum drying, obtain extract;
(3) extract is well mixed with lidocaine, Vitwas E, adds 5 parts of 2 parts of polyethylene glycol and ethanol, 30-40 DEG C is heated to after mixing, constant temperature stirring, was both obtained.
The process for preparing medicine of experimental group 5 is as follows:
(1) 2 parts of the red sage root, 1 part of safflower, 2 parts of chrysanthemum indicum, 3 parts of the dried venom of toads;
(2) the Chinese medicine material red sage root, safflower, chrysanthemum indicum, the dried venom of toads, 8 times of water of dosing material total amount, refluxing extraction are taken by weight Twice, every time 1 hour, decoction merged, filtration, is concentrated into liquor strength and reaches 1.15g/ml, adds ethanol to alcohol content and is 70%, stand overnight, centrifuge, take supernatant, concentrate, vacuum drying, obtain extract;
(3) extract is well mixed with 5 parts of 2 parts of polyethylene glycol and ethanol, 30-40 DEG C is heated to after mixing, constant temperature stirs Mix, both.
The process for preparing medicine of experimental group 6 is as follows:
(1) 2 parts of the red sage root, 1 part of safflower, 2 parts of lidocaine, 1 part of Vitwas E;
(2) the Chinese medicine material red sage root, safflower are taken by weight, and 8 times of water of dosing material total amount, twice, 1 is small every time for refluxing extraction When, decoction merges, filtration, is concentrated into liquor strength and reaches 1.15g/ml, and it is 70% to add ethanol to alcohol content, is stood overnight, Centrifugation, takes supernatant, concentrates, and vacuum drying, obtains extract;
(3) extract is well mixed with lidocaine, Vitwas E, adds 5 parts of 2 parts of polyethylene glycol and ethanol, 30-40 DEG C is heated to after mixing, constant temperature stirring, was both obtained.
The process for preparing medicine of experimental group 7 is as follows:
(1) 2 parts of chrysanthemum indicum, 3 parts of the dried venom of toads, 2 parts of lidocaine, 1 part of Vitwas E;
(2) take Chinese medicine material chrysanthemum indicum, the dried venom of toads by weight, 8 times of water of dosing material total amount, refluxing extraction twice, every time 1 Hour, decoction merges, filtration, is concentrated into liquor strength and reaches 1.15g/ml, and it is 70% to add ethanol to alcohol content, is stood At night, centrifugation, supernatant is taken, concentrated, vacuum drying, obtain extract;
(3) extract is well mixed with lidocaine, Vitwas E, adds 5 parts of 2 parts of polyethylene glycol and ethanol, 30-40 DEG C is heated to after mixing, constant temperature stirring, was both obtained.
Experimental result is as shown in table 1.
Pain threshold after each group drug administration of table 1
Note:Compared with before administration, * P<0.01, * * P<0.05.
Compared with before administration, 1-24h after administration, experimental group 1 can significantly improve the hot plate induced pain mouse threshold of pain, and difference has system Meter learns meaning (P<0.01) mouse pain threshold can be significantly improved by, showing the pharmaceutical composition of the present invention, and there is obvious analgesia to make With.1-4h upon administration, experimental group 1 is compared with experimental group 2, and the threshold of pain of experimental group 1 is significantly higher than in the case of Isodose (the P of experimental group 2<0.01), the onset time of experimental group 1 is shorter, shows the pharmaceutical composition onset of pain control of the present invention faster.It is being administered 8-24h afterwards, experimental group 1 is compared with experimental group 2, and the threshold of pain of experimental group 1 is significantly higher than the (P of experimental group 2 in the case of Isodose <0.05), show that the pharmaceutical composition analgesic effect of the present invention is more preferable.Similarly, experimental group 1 can draw phase compared with experimental group 3-7 Same conclusion.
The analgesic activity of the pharmaceutical composition Dichlorodiphenyl Acetate induced pain mouse of the present invention of embodiment 4
Body weight 18-22g healthy male mices are taken, are randomly divided into 9 groups, packet and dosage are same as Example 3, by medicine Thing is coated on mouse tail, and drug coat area is 1-2cm2, covered and fixed with not sensitization adhesive plaster, last dose 12h pneumoretroperitoneums 0.6% acetic acid 0.2mL/10g is injected, records writhing number in mouse 15min, writhing standard is that mouse body elongates, belly flesh Tension force increases, and forelimb extensions simultaneously stretch with one or both sides hind leg.
Medicine analgesic percentage (%)=(control group writhing number-administration group writhing number)/control group writhing number
The analgesic activity of each group medicine Dichlorodiphenyl Acetate induced mice writhing of table 2
Note:The * P compared with aspirin group<0.01, * * P<0.05.Compared with matrix control group, #P<0.01, ##P< 0.05。
The analgesic experiment result of table 2 shows that pharmaceutical composition of the invention can reduce the writhing response number of mouse, and right Compare according to group with significant difference (P<0.01), show that pharmaceutical composition provided by the invention has good analgesic activity. For experimental group 1 compared with aspirin group, the pain inhibiting rate of the Dichlorodiphenyl Acetate induced mice writhing of experimental group 1 is significantly higher than aspirin Group (P<0.01).Experimental group 2-7 is compared with aspirin group, no significant difference (P>0.05).Show in the present invention Drug composition is compared with aspirin group with more preferable analgesic effect.
The anti-inflammatory of embodiment 5 is tested
Body weight 18-22g healthy male mices are taken, are randomly divided into 2 groups, respectively experimental group and control group, every group of mouse 10 Only, the μ L of dimethylbenzene 50 are uniformly coated on the auris dextra two sides of every mouse, left ear is untreated to be compareed as self-blank, causes inflammation 30 After minute, the coating solution prepared by the experimental mice auris dextra coating embodiment of the present invention 2, painting dose is 0.3g, physiological saline Control group coats the physiological saline of equivalent, and administration takes off cervical vertebra after 1 hour and puts to death mouse, cleans ear and apply medicine, along auricle base Line cuts two ears, sweeps away the same position disk of left and right ear with 8mm card punch, weighs, and calculates the ear method of double differences, swelling=auris dextra circle Piece weight-left ear disk weight.Experimental result is as shown in table 3:
The medicine paraxylene of the present invention of table 3 causes the influence of mice ear
Group Dosage (g/kg) n Swelling (mg)
Saline control group - 12 9.68±2.20
Experimental group 0.3g 12 4.25±1.04
As shown in Table 3, compared with control group, the swelling of experimental mice significantly reduces experimental group, this explanation The pharmaceutical composition of the present invention has preferable antiinflammation.
The toxicity test of embodiment 6
The coating solution for taking the embodiment of the present invention 2 to prepare, 20 mouse are caused by acute oral toxicity test detection half Dead amount, LD50>4g/kg, according to LD50=5g/kg calculates cumulative toxicity poisoning dosage, and the 1-5 days dosage is 0.1LD50, often afterwards The 0.5 times of dosage of increase in 5 days, until 20 days, dead animal quantity is counted, it is dead without experimental animal during as a result showing medication Die, show that the drug oral of the present invention is non-toxic.
Take rat 10, leaching tail method taken after depilation, is administered 24 hours, dosage 5g/kg, experimental animal without death, Rat is put to death and dissected, pathological observation is carried out, phenomenon without exception, shows transdermal drug delivery thing toxicity of the invention.
The present invention of embodiment 7 can packing type field operation quick needle insertion device (one)
Fig. 1-Fig. 8 is referred to, accompanying drawing 1 is that the present invention can packing type field operation quick needle insertion device structural representation.Accompanying drawing 2-5 is The needle inserter structural representation of different conditions is in during use.Accompanying drawing 6 is the structural representation of promotion part, and accompanying drawing 7-8 is to push away Enter portion along housing radial cross section.
The reference and part being related in accompanying drawing are as follows:
1. housing, 2. acupuncture needle storage parts, 3. ejection broken skin portions, 4. promotion parts, 5. acupuncture needle cylinders, 6. dividing plates, 7. acupuncture needle holes, 8. Perforation, 9. push rods, 10. cut somebody's hair, 11. resilient clips, and 12. press pressing spring, and 13. back-moving springs, 14. spring dead plates, 15. hit Platform, 16. hit clamp, and 17. inserting needle working chambers, 18. protrusion buttons, 19. elastic force lockholes, 20. impact heads, 21. hit button, 22. lockhole is hit, 23. puncture working chambers, 24. stretches push rods, 25. bodies of rod, 26. baffles, 27. impact head baffle plates, 28. millis Pin baffle plate, 29. housing elongated slots, 30. cavity elongated slots, 31. scale markers, 32. acupuncture needles, 33. stretchable specifications, 34. stretch rods.
One kind can packing type field operation quick needle insertion device, including housing 1, acupuncture needle storage part 2, ejection broken skin portion 3, promotion part 4, The acupuncture needle storage part 2 includes acupuncture needle cylinder 5, dividing plate 6, and the acupuncture needle cylinder 5 is cylinder, is used to store up provided with some in acupuncture needle cylinder 5 Deposit the acupuncture needle hole 7 of acupuncture needle, the acupuncture needle (acupuncture needle) 32 prepared in the acupuncture needle hole 7 provided with embodiment 2, the number in the acupuncture needle hole 7 Measure as 5-20, acupuncture needle hole 7 is uniformly distributed around the central axis of acupuncture needle cylinder 5, and the dividing plate 6 is cylindrical flat board, is set on dividing plate 6 There is perforation 8, acupuncture needle cylinder 5 and the be hinged fixation of dividing plate 6, acupuncture needle cylinder 5 can rotate around the axis of cylinder, and rotation acupuncture needle cylinder 5 can make difference Acupuncture needle hole 7 is corresponding with perforation 8.The housing 1 is the small column of the big lower end diameter of upper end diameter, the upper end of housing 1 and dividing plate 6 It is fixedly connected, the side of housing 1 is provided with elastic force lockhole 19, hits lockhole 22;The ejection broken skin portion 3 includes push rod 9, cut somebody's hair 10th, resilient clip 11, by pressing spring 12, back-moving spring 13, spring dead plate 14, hit platform 15, hit clamp 16, inserting needle work Chamber 17;The inserting needle working chamber 17 is corresponding with the perforation 8 on dividing plate 6, and inserting needle working chamber is arranged on the inner surface of housing 1;It is described Push rod 9 is slidably connected with acupuncture needle cylinder 5 and dividing plate 6, and one end of push rod 9 passes from the end face of acupuncture needle cylinder 5, the other end and 10 fixations of cutting somebody's hair Connection;Described cut somebody's hair 10 is provided with resilient clip 11, and the resilient clip 11 is flexible arm structure, and its one end is with pushing away First 10 are fixedly connected, and the other end is mobilizable protrusion button 18, and protrusion button 18 matches with elastic force lockhole 19 and can be from elastic force Passed in lockhole 19, when pressing push rod 9, the inner surface of protrusion button 18 from housing 1 slides into lockhole 19, in the effect of elastic force Lower protrusion button 18 is passed from elastic force lockhole 19 by push rod 9,10 lockings of cutting somebody's hair.Described cut somebody's hair is additionally provided with by pressing spring on 10 12nd, back-moving spring 13, the back-moving spring 13 are connected with being fixed on the spring dead plate 14 of the inner surface of housing 1, and pressing push rod 9 can Make to cut somebody's hair between 10 and spring dead plate 14 and produce reseting elasticity;It is described to be connected by pressing spring 12 with hitting platform 15, the shock Platform 15 divides for impact head 20 and hits the two parts of clamp 16, and the shock clamp 16 is flexible arm structure, its one end It is fixedly connected with hitting platform 15, the other end is mobilizable shock button 21, hits button 21 and matches simultaneously with hitting lockhole 22 Locking can be passed from lockhole 22 is hit, when protrusion button 18 passes locking in elastic force lockhole 19, cut somebody's hair 10 with hitting platform 15 Between be in compressive state by pressing spring 12, now pressing hit button 21, hit button 21 from hit lockhole 22 slide to shell The inner surface of body 1, hit platform 15 and unlock and hit stretches push rod 24 under by the effect of the elastic force of pressing spring 12;
The promotion part 4 includes puncture working chamber 23 and stretches push rod 24, and the puncture working chamber 23 is arranged on housing 1 Inner surface is simultaneously corresponding with the cavity of inserting needle working chamber 17, and the stretches push rod 24 includes the body of rod 25 and is fixed on the body of rod 25 Baffle 26, impact head baffle plate 27, acupuncture needle baffle plate 28, the acupuncture needle baffle plate 28 are arranged on puncture working chamber 23 and inserting needle work In chamber 17, the impact head baffle plate 27 is arranged on the stage casing of the body of rod 25 and corresponding with impact head 20, and the housing 1 is provided with along milli The housing elongated slot 29 of the axis direction of syringe 5, the inserting needle working chamber 17, puncture working chamber 23 are provided with along the axis side of acupuncture needle cylinder 5 To cavity elongated slot 30, the housing elongated slot 29 is provided with scale marker 31 (not marked in figure), and the head end of the body of rod 25 is from housing Passed in elongated slot 29, the tail end of the body of rod 25 is passed through from cavity elongated slot 30 and fixed with the body of rod 25, and baffle 26, which is arranged on, hits Tap the head between baffle plate 27 and housing elongated slot 29, the cavity cross-sectional area of the puncture working chamber 23 is less than the cavity of inserting needle working chamber 17 Cross-sectional area, the shape of acupuncture needle baffle plate 28 and the cross-sections match of puncture working chamber 23, acupuncture needle baffle plate 28 can be along inserting needle working chamber 17 slide up and down;When acupuncture needle baffle plate 28 is slided into puncture working chamber 23, because the volume of acupuncture needle baffle plate 28 works less than inserting needle The cavity cross-sectional area of chamber 17, acupuncture needle baffle plate 28 and the body of rod 25 can pull out shape along the axis push-and-pull of the body of rod 25 when the body of rod 25 is in During state, inserting needle working chamber 17 is in connected state (as shown in Figure 7) with puncture working chamber 23, and now acupuncture needle can work from inserting needle Chamber 17 enters in puncture working chamber 23;When the body of rod 25 is in advanced state, acupuncture needle baffle plate 28 is by inserting needle working chamber 17 with puncturing Working chamber 23 separates, and now inserting needle working chamber 17 is in connected state isolation (as shown in Figure 8) with puncture working chamber 23.
The present invention of embodiment 8 can packing type field operation quick needle insertion device (two)
Fig. 9 is referred to, the present embodiment is substantially the same manner as Example 7, and difference is:The surface of housing 1 is additionally provided with Stretchable specification 33;Described one end of stretchable specification 33 is fixed with housing 1, and the other end is stretch rod 34.It is described to draw The specification 33 stretched is made up of flexible paper, and the operation instruction of the present invention is recorded on its surface, and specification natural shrinking is crimped onto shell The surface of body 1, stretch rod 34 can be embedded in the groove (not shown) on the surface of housing 1 and fix stretchable specification 334.Use Person can be deployed specification by stretch rod.
Application method:Rotation acupuncture needle cylinder 5 is corresponding with perforation 8 by acupuncture needle hole 7, and the acupuncture needle 32 in acupuncture needle cylinder 5 enters from perforation 8 Into inserting needle working chamber 17, acupuncture needle is stopped to the upper end of acupuncture needle baffle plate 28, with pressing push rod 9, will protrude button 18 from housing 1 Inner surface is pushed into the position of lockhole 19, and protrusion button 18 is passed from elastic force lockhole 19 in the presence of elastic force, by push rod 9, pushed away First 10 locking, is now in compressive state (as shown in Figure 2) by pressing spring 12, back-moving spring 13;Pull stretches push rod 24, make into Pin working chamber 17 connects with puncture working chamber 23, and acupuncture needle 32 enters and is retained in puncture working chamber 23 (as shown in Figure 3);It will stretch Contracting push rod 24 promotes, and makes the corresponding puncture working chamber 23 of acupuncture needle baffle plate 28, and the end of puncture working chamber 23 is entered into pin hole alignment needs Button 21 is hit in the acupuncture point of puncture, pressing, hits button 21 from lockhole 22 is hit and slides to the inner surface of housing 1, hits platform 15 and releases Lock and be active, it is 10 locked due to cutting somebody's hair, now hit platform 15 and hit in the case where being acted on by the elastic force of pressing spring 12 Stretches push rod 24 (as shown in Figure 4), the head end of acupuncture needle 32 broken skin in the presence of impact are pierced into skin (as shown in Figure 5), tune Section stretches push rod 24 simultaneously aids in the piercing depth that scale marker 31 adjusts acupuncture needle 32, releases needle inserter, acupuncture needle 32 vertically upward Then stay on skin.Pressing protrusion button 18, push rod 9 are upspring under the elastic force effect of back-moving spring 13, now rotate acupuncture needle cylinder 5 Next piece of acupuncture needle 32 is set to enter state to be penetrated from multiple above-mentioned steps.
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art Member, on the premise of the inventive method is not departed from, can also make some improvement and supplement, and these are improved and supplement also should be regarded as Protection scope of the present invention.

Claims (7)

  1. A kind of 1. pharmaceutical composition of anti-inflammatory analgesic, it is characterised in that described pharmaceutical composition by parts by weight as described below original Material medicine is made:2 parts of the red sage root, 1 part of safflower, 2 parts of chrysanthemum indicum, 3 parts of the dried venom of toads, 2 parts of lidocaine, 1 part of Vitwas E.
  2. 2. a kind of acupuncture needle with anti-inflammatory analgesic effect, including acupuncture needle body and the medicine coated in acupuncture needle body surface Coating, it is characterised in that the medication coat is made up of claim 1 described pharmaceutical composition.
  3. 3. there is the acupuncture needle of anti-inflammatory analgesic effect according to claim 2, it is characterised in that the preparation side of the acupuncture needle Method is as follows:
    (1) 2 parts of the Chinese medicine material red sage root, 1 part of safflower, 2 parts of chrysanthemum indicum, 3 parts of the dried venom of toads, 8 times of water of dosing material total amount, refluxing extraction are taken Twice, every time 1 hour, decoction merged, filtration, is concentrated into liquor strength and reaches 1.15g/ml, adds ethanol to alcohol content and is 70%, stand overnight, centrifuge, take supernatant, concentrate, vacuum drying, obtain extract;
    (2) extract is well mixed with 2 parts of lidocaine, 1 part of Vitwas E, adds 2 parts of polyethylene glycol and ethanol 5 Part, 30-40 DEG C is heated to after mixing, constant temperature stirs to obtain coating solution;
    (3) coating solution is added to coating machine, the Vltrasonic device power for adjusting the coating machine is 5-50W, after atomization Coating solution be sprayed on the acupuncture needle body surface, both.
  4. 4. one kind can packing type field operation quick needle insertion device, it is characterised in that the needle inserter includes housing (1), acupuncture needle stores Portion (2), ejection broken skin portion (3), promotion part (4), the acupuncture needle storage part (2) include acupuncture needle cylinder (5), dividing plate (6), the acupuncture needle Cylinder (5) is cylinder, and some acupuncture needle holes (7) for being used to store acupuncture needle are provided with acupuncture needle cylinder (5), are provided with acupuncture needle hole (7) such as power Profit requires the acupuncture needle (32) described in 2, and the dividing plate (6) is provided with perforation (8), acupuncture needle cylinder (5) and the be hinged fixation of dividing plate (6), Acupuncture needle cylinder (5) can rotate around the axis of cylinder, during rotation difference acupuncture needle hole (7) with perforate (8) it is corresponding;
    The housing (1) is fixedly connected with dividing plate (6), and housing (1) is provided with elastic force lockhole (19) and hits lockhole (22);It is described Ejection broken skin portion (3) include push rod (9), cut somebody's hair (10), resilient clip (11), by pressing spring (12), back-moving spring (13), spring Fixed plate (14), hit platform (15), hit clamp (16), inserting needle working chamber (17);The inserting needle working chamber (17) and dividing plate (6) On perforation (8) it is corresponding, inserting needle working chamber is arranged on the inner surface of housing (1);The push rod (9) and acupuncture needle cylinder (5) and dividing plate (6) be slidably connected, one end of push rod (9) passes from acupuncture needle cylinder (5) end face, the other end with cut somebody's hair (10) be fixedly connected;It is described to push away Head (10) is provided with resilient clip (11), and the resilient clip (11) is flexible arm structure, and its one end is with cutting somebody's hair (10) it is fixedly connected, the other end is mobilizable protrusion button (18), and protrusion button (18) matches with elastic force lockhole (19) and can Passed from elastic force lockhole (19), when pressing push rod (9), protrusion button (18) slides into lockhole from the inner surface of housing (1) (19), locking is passed from elastic force lockhole (19) in the presence of elastic force;Described cut somebody's hair (10) are provided with by pressing spring (12), again Position spring (13), the back-moving spring (13) are connected with being fixed on the spring dead plate (14) of housing (1) inner surface, press push rod (9) make to cut somebody's hair (10) and reseting elasticity is produced between spring dead plate (14), it is described to connect by pressing spring (12) with hitting platform (15) Connect, the shock platform (15) is divided into impact head (20) and hits clamp (16) two parts, and the shock clamp (16) is with bullet Property arm structure, its one end with hit platform (15) be fixedly connected, the other end for it is mobilizable shock button (21), hit button (21) match with shock lockhole (22) and locking can be passed from lockhole (22) is hit, when protrusion button (18) is in elastic force lockhole (19) when locking is passed in, cutting somebody's hair (10) and hitting produces elastic force between platform (15), and button (21) is hit in now pressing, and shock is pressed Key slides to housing (1) inner surface from lockhole (22) is hit, and hits platform (15) and unlocks and in the elastic force work by pressing spring (12) With lower shock stretches push rod (24);
    The promotion part (4) includes puncture working chamber (23) and stretches push rod (24), and the puncture working chamber (23) is arranged on shell The inner surface of body (1) is simultaneously corresponding with inserting needle working chamber (17), and the stretches push rod (24) includes the body of rod (25) and is fixed on the body of rod (25) baffle (26), impact head baffle plate (27) on, acupuncture needle baffle plate (28), the acupuncture needle baffle plate (28) set puncture working In chamber (23), the impact head baffle plate (27) is arranged on the stage casing of the body of rod (25) and, the housing (1) corresponding with impact head (20) The housing elongated slot (29) along acupuncture needle cylinder (5) axis direction is provided with, the inserting needle working chamber (17), puncture working chamber are set on (23) There is the cavity elongated slot (30) along acupuncture needle cylinder (5) axis direction, the housing elongated slot (29) is provided with scale marker (31), the body of rod (25) head end passes from housing elongated slot (29), the tail end of the body of rod (25) passed through from cavity elongated slot (30) and with the body of rod (25) Fixed, baffle (26) is arranged between impact head baffle plate (27) and housing elongated slot (29), the puncture working chamber (23) Cavity cross-sectional area is less than inserting needle working chamber (17) cavity cross-sectional area, shape and the puncture working chamber (23) of acupuncture needle baffle plate (28) Cross-sections match, acupuncture needle baffle plate (28) can slide up and down along inserting needle working chamber (17), puncture working chamber (23).
  5. 5. according to claim 4 can packing type field operation quick needle insertion device, it is characterised in that the number of the acupuncture needle hole (7) Measure as 5-20, acupuncture needle hole (7) are uniformly distributed around acupuncture needle cylinder (5) central axis.
  6. 6. according to claim 4 can packing type field operation quick needle insertion device, it is characterised in that housing (1) surface is also Provided with stretchable specification (33);One end of the stretchable specification (33) is fixed with housing (1), and the other end is stretch rod (34)。
  7. 7. according to claim 6 can packing type field operation quick needle insertion device, it is characterised in that the stretchable specification (33) it is made up of flexible paper, specification natural shrinking is crimped onto housing (1) surface, and stretch rod (34) can be embedded in housing (1) table It is in the groove in face that stretchable specification (33) is fixed.
CN201710531558.6A 2017-07-03 2017-07-03 The acupuncture needle of a kind of anti-inflammatory analgesic and can packing type field operation quick needle insertion device Pending CN107456386A (en)

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CN102370776A (en) * 2011-11-17 2012-03-14 中国中医科学院中医临床基础医学研究所 Chinese medicinal compound preparation for treating prostatitis and preparation method thereof
CN104491324A (en) * 2014-12-04 2015-04-08 刘栋 Aerosol for postoperative patient to promote blood circulation and remove obstruction in channels
CN105596584A (en) * 2015-09-21 2016-05-25 钱培培 Traditional Chinese medicine preparation special for local anesthesia and preparation method thereof
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109248089A (en) * 2018-11-23 2019-01-22 叶春生 A kind of pen type thumb is pushed pin acupuncture-moxibustion therapy needling device
CN109248089B (en) * 2018-11-23 2021-10-26 叶春生 Pen type thumb push needle acupuncture needle inserting device
CN112121079A (en) * 2020-09-24 2020-12-25 长春中医药大学 Acupuncture needle capable of enhancing pain relieving efficacy and preparation method and application thereof

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