CN107412409A - The new medicine use of shiny-leaved yellowhorn woody part and blade - Google Patents

The new medicine use of shiny-leaved yellowhorn woody part and blade Download PDF

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Publication number
CN107412409A
CN107412409A CN201710645435.5A CN201710645435A CN107412409A CN 107412409 A CN107412409 A CN 107412409A CN 201710645435 A CN201710645435 A CN 201710645435A CN 107412409 A CN107412409 A CN 107412409A
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shiny
medicine
leaved yellowhorn
blade
gout
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CN201710645435.5A
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Chinese (zh)
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师海全
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/77Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/17Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to drug field, more particularly to the purposes of shiny-leaved yellowhorn woody part and blade in preparing treatment gout or preventing the medicine of purine metabolic disturbance.Comprise the following steps:A, gather fresh clean, in green, without go mouldy, insect pest, residues of pesticides shiny-leaved yellowhorn woody part and leaf portion;B, sliced, frying, it is made after drying and can extracts or decoction or electuary and traditional Chinese medicine and Mongolia Medicine medicinal material used in patent medicine.Beneficial effect:The present invention is in gout, clinical verification is given with shiny-leaved yellowhorn medicine materical crude slice with the patient of oral colchicin and other purine piece in the form of brewing and contrasted in the crowd of purine metabolic disturbance diseases, wherein 95% patient symptom mitigates or disappeared, and does not find toxic side effect, and effect is unexpectedly more obvious.

Description

The new medicine use of shiny-leaved yellowhorn woody part and blade
Technical field
The present invention relates to drug field, more particularly to traditional Chinese medicine and Mongolia Medicine shiny-leaved yellowhorn woody part and blade to prepare treatment pain Medicinal usage in wind or prevention purine metabolic disturbance diseases.
Background technology
Shiny-leaved yellowhorn (Xanthoceras sorbifoliaBunge.), it is that the distinctive woody oleiferous plants in China and Medicinal are planted Thing, according to《National Chinese herbal medicine compilation》、《Chinese book on Chinese herbal medicine》Found etc. the medicine pharmacology about shiny-leaved yellowhorn and the scope of clinical practice, its All it is used as medicine with the woody part and blade of shiny-leaved yellowhorn, for oral administration or external application.Major function:Dispelling wind and eliminating dampness;Swelling and pain relieving.Main beriberoid pyretic arthralgia; Arthralgia and myalgia.The entitled hila of anaesthetic is gloomy to be stepped on, and energy wind-damp dispelling, swelling and pain relieving, holds back dry yellow water, is clinically used for treating rheumatic pass Section is scorching, the disease such as heat, skin rheumatism in rheumatism.But at present in addition to finding its above effect purposes, in Other diseases especially It is that medicinal application in gout and purine metabolic disturbance diseases has no and realizes direction.The traditional Chinese medical science think goat more by diseases caused by external factors it is damp and hot it Evil or chill the strongly fragrant longization heat of heresy, or internal injury kidney deficiency and liver or bi Zheng are with the passing of time, blood stasis phlegm hinders and caused.Though belong to rheumatism, its pain Acutely, recurrent exerbation, it is touching not to be cured, so that joint deformity, and have multiple complications, therefore again not in general rheumatism.Doctor trained in Western medicine thinks Gout be largely be deposited between joint by uric acid crystal thing caused by.Uric acid is a kind of inevitable metabolite in human body.Just In the case of often, uric acid can be delivered to kidney by blood and be excreted with urine.The excessive uric acid of body, can form crystal, deposit Intra-articular, cause severe pain.When human body serum Uric Acid Concentration is too high, uric acid i.e. be deposited in the form of sodium salt joint, soft tissue, In cartilage and kidney, cause the foreign matter inflammation of tissue.Often occur in foot articulationes metatarsophalangeae, thumb joint or heel, instep, ankle Joint or other joints, affected joints are made to occur shouting pain, the heating of short time inner skin is simultaneously congested until arthroncus, 24 hours Peak, sharp ache are inside can reach, the lighter free regression, severe one can will continue more days or a few weeks, most gouts within a few hours Will recurrence.As treated not in time, then chronic, chronicity disease is easily formed, and permanent lesion is caused to joint, not only influenceed Normal life, the working and learning of patient, more seriously endanger the health of patient.And lithate is the one kind found in urine White, tasteless crystal, it is practically insoluble in water, ethanol and ether, but is dissolved in basic salt.The medicine of existing treatment gout Such as:Benzbromarone (skin graft immediately), its main mechanism are the great absorptions for resisting renal tubule to uric acid, increase renal tubule pair The excretion of uric acid;Allopurinol, resist the generation of uric acid;This kind of medicine is often accompanied by gastrointestinal reaction diarrhoea, upset,gastro-intestinal, skin Rash, leucocyte and writes platelet reduction, liver function damage, the toxicity, side effect such as toxicity epithelium necrosis, moreover, being once discontinued, can answer again Hair, it is impossible to effect a radical cure.Compound nerve capsule, although redness and swelling of joints, heat pain, joint stuffiness caused by gout caused by hot stasis blocking being treated Deng disease, but sour and astringent and purine-containing the food of necessary fasting raw food during medication, such as seafood, bean product and other nutriments Deng, easily cause body malnutrition, resistance, immunity degradation and cause the adverse consequences such as Other diseases.Therefore the disease Prevention and treatment also become the problem that current medical field is not captured.
It is a discovery of the invention that contain saponin of Lignum Xanthoceratis (20.3mg/100g) in fresh and tender shiny-leaved yellowhorn trees portion and blade respectively Triterpenoid saponin (30.3mg/100g) flavones (29.76mg/100g) polyphenol (29.6GAEmg/100g) isoreactivity drug ingedient and Calcium (489.4mg/100g) iron (21.3mg/100g) potassium (1820.9mg/100g), zinc (3.9mg/100g) magnesium (78.2mg/ The trace element such as 100g).The ingenious combination of these active pharmaceutical ingredients and trace element and its content ratio contained by it is not But it can effectively prevent the repetition of human body protein nutrition from absorbing, increase the wriggling and number of micturitions of bladder, so as to improve kidney Purine metabolism function, the uric acid content in blood is reduced, prevent acid sodium-salt from crystallizing to be formed, promote the discharge of blood uric acid, alleviate disease People's pain, progressively degrade focus acid sodium-salt crystalline material, with this reach radical cure gout and caused by purine metabolic disturbance its The purpose of his disease.The present invention verifies that there is the generation for suppressing high lithemia sodium salt crystal to make in shiny-leaved yellowhorn branches and leaves portion by clinic application With, there is good preventive and therapeutic action to gout or purine metabolic disturbance diseases, it is fast for preparing treatment gout and prevention The medicine or Food and hygienical food of purine metabolic disturbance diseases, and it is without any side effects to human body.Shiny-leaved yellowhorn woody part and leaf The new medicine use of piece.
The purpose of invention:In order to provide a kind of medicine and emphasis using the effect of the medicine of shiny-leaved yellowhorn woody part and blade.
In order to reach as above purpose, the present invention adopts the following technical scheme that:
Scheme one:
The purposes of shiny-leaved yellowhorn woody part and blade in the medicine or health food for preparing treatment gout.
Scheme two:
The purposes of shiny-leaved yellowhorn woody part and blade in the medicine or health food for preparing prevention purine metabolic disturbance diseases.
Scheme three:
Shiny-leaved yellowhorn woody part and blade are used to treat the use in gout and urarthritis or health food in prescription On the way.
Scheme four:
Shiny-leaved yellowhorn woody part blade is used to prevent in purine metabolic disturbance diseases or Food and hygienical food in prescription Purposes
Scheme five:Treat the medicine of gout, it is characterised in that comprise the following steps:
A gather it is fresh and tender, clean, without go mouldy, the woody part and blade of the shiny-leaved yellowhorn of insect pest and residues of pesticides;
B is sliced, system, dry after be made and can extract or decoct soup or brew tablet used.
Further technical scheme of the invention is, the frying refer to by after the fresh and tender sliced segmentation of shiny-leaved yellowhorn woody part with After fresh leaves are according to the ratio mixing that wooden leaf ratio is 3: 7, it is placed in environment temperature frying half an hour under conditions of 90 DEG C, dries Refer to the above-mentioned article after frying is placed in dehydration system under 50--75 DEG C of environmental condition and done to moisture content to be not more than 7% Dry product.
Using the present invention of as above technical scheme, had the advantages that relative to prior art:The present invention is fast in gout Used in the crowd of purine metabolic disturbance diseases fresh and tender shiny-leaved yellowhorn woody part and blade made of medicine materical crude slice in the form of brewing with it is oral The patient of colchicin and other purine tablet gives clinical verification and contrasted, wherein:Gout and gouty are suffered to part The directly oral colchicin of the patient of acute arthritis and other purine piece, except the symptom to some patients have some mitigations with Outside, but therapeutic effect and unobvious.The present invention see and treat patients altogether since two thousand and ten gout and gouty acute arthritis patient it is near Thousand and all orally found for patient in the form of shinyleaf yellowhorn fruit shell medicine materical crude slice brews, the curative competence of clinical effectiveness of the invention More than 95%, and toxic side effect is not found, effect is unexpectedly more obvious.
Embodiment
Embodiments of the invention are illustrated below, embodiment is not construed as limiting the invention:
Shiny-leaved yellowhorn woody part and blade are preparing the purposes in treating and preventing gout medicine or health food.
Shiny-leaved yellowhorn woody part and blade are in treatment and prevention purine metabolic disturbance diseases medicine or health food is prepared Purposes.
Treat the medicine of gout, it is characterised in that comprise the following steps:
A gather it is fresh and tender, clean, without go mouldy, the woody part and blade of the shiny-leaved yellowhorn of insect pest and residues of pesticides;
B is sliced, system, dry after be made and can extract or decoct soup or brew tablet used.
Further technical scheme of the invention is, the frying refer to by after the fresh and tender sliced segmentation of shiny-leaved yellowhorn woody part with After fresh leaves are according to the ratio mixing that wooden leaf ratio is 3: 7, it is placed in environment temperature frying half an hour under conditions of 90 DEG C, dries Refer to the above-mentioned article after frying is placed in dehydration system under 50--75 DEG C of environmental condition and done to moisture content to be not more than 7% Dry product.
The substantive distinguishing features of the present invention can be found out by following:Seen and treated patients altogether since 20010 gout and gout of the invention The arthritic patient nearly thousand of impatient property and medicine materical crude slice made of fresh and tender shiny-leaved yellowhorn woody part and blade is all used in the form of brewing Orally found for patient, the curative competence of clinical effectiveness of the invention does not find toxic side effect more than 95%, and effect is unexpectedly It is more obvious.
Clinical experiment report (part)
General principle, principal character and the advantages of the present invention of the present invention has been shown and described above.The technology of this area Personnel should be recognized that the present invention is not limited to the above embodiments, simply illustrate this hair described in above-described embodiment and specification Bright principle, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, these changes Both fallen within improving in claimed scope.
It is related to the bibliography of the present invention:
1st, the Primary Study of shiny-leaved yellowhorn study on chemical compositions of leaves《Chinese Wild plant》03 phase in 1989.Author:Zhu Dan, Wang Hong Bucket;
2nd, shiny-leaved yellowhorn study on chemical compositions of leaves is studied《Chinese patent drug》10 phases in 2010.Author:Ma Yangmin, king wear;
3rd, the chemical constitution study of anaesthetic wood of shiny-leaved yellowhorn《Medical Colleges of the Inner Mongol's master's research paper》2008.11.01.Author: Wang Hongwei.;
4th, wood of shiny-leaved yellowhorn chemical constitution study《Beijing University of Chinese Medicine's journal》12 phases in 2008.Author:Dong Yu, Wang Hongwei Deng;
5th, the edible and medical value of shiny-leaved yellowhorn《Chinese Medicine guide》2006. the 10th phases.Author:Wang Lihua.

Claims (4)

1. shiny-leaved yellowhorn woody part and blade are in treatment and prevention gout and urarthritis medicine or health food is prepared Purposes.
2. shiny-leaved yellowhorn woody part and blade position are preparing the use in treating and preventing purine metabolic disturbance diseases medicine or health food On the way.
3. treat the medicine of gout, it is characterised in that comprise the following steps:
A gather it is fresh and tender, clean, without go mouldy, the woody part and blade of the shiny-leaved yellowhorn tree of insect pest and residues of pesticides;
B is sliced, frying, dry after be made can extract decoct soup or brew and patent medicine used in tablet.
4. the medicine for the treatment of gout as claimed in claim 3, it is characterised in that the frying refers to fresh and tender shiny-leaved yellowhorn wood After being mixed after the sliced segmentation in portion with fresh leaves according to the ratio that wooden leaf ratio is 3: 7, condition of the environment temperature at 90 DEG C is placed in Lower frying half an hour, dry refer to by the above-mentioned article after frying be placed under 50--75 DEG C of environmental condition be dehydrated system do to Moisture content is not more than 7% dry product.
CN201710645435.5A 2017-07-24 2017-07-24 The new medicine use of shiny-leaved yellowhorn woody part and blade Pending CN107412409A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112042845A (en) * 2020-10-15 2020-12-08 松林 Xanthoceras sorbifolia leaf beverage and preparation method thereof
CN116870068A (en) * 2023-08-07 2023-10-13 内蒙古科技大学包头医学院 Application of shinyleaf yellowhorn leaf in preparation of medicine for preventing and treating hyperuricemia nephropathy

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103988957A (en) * 2014-05-12 2014-08-20 师海全 Health care tea prepared by using narrow leaves and tender branches of wood of shinyleaf yellowhorn
CN106668276A (en) * 2015-11-05 2017-05-17 甘肃长瑞文冠果产业发展有限公司 Tea and health food for treating gout and medical application thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103988957A (en) * 2014-05-12 2014-08-20 师海全 Health care tea prepared by using narrow leaves and tender branches of wood of shinyleaf yellowhorn
CN106668276A (en) * 2015-11-05 2017-05-17 甘肃长瑞文冠果产业发展有限公司 Tea and health food for treating gout and medical application thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
许良等: "微波消解-电感耦合等离子体原子发射光谱(ICP-AES)法测定蒙药材文冠木中16种元素", 《中国无机分析化学》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112042845A (en) * 2020-10-15 2020-12-08 松林 Xanthoceras sorbifolia leaf beverage and preparation method thereof
CN116870068A (en) * 2023-08-07 2023-10-13 内蒙古科技大学包头医学院 Application of shinyleaf yellowhorn leaf in preparation of medicine for preventing and treating hyperuricemia nephropathy

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Application publication date: 20171201