CN107412338A - A kind of Chinese medicine composition and the plaster containing said composition - Google Patents
A kind of Chinese medicine composition and the plaster containing said composition Download PDFInfo
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- CN107412338A CN107412338A CN201710602098.1A CN201710602098A CN107412338A CN 107412338 A CN107412338 A CN 107412338A CN 201710602098 A CN201710602098 A CN 201710602098A CN 107412338 A CN107412338 A CN 107412338A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
- A61K36/126—Drynaria
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- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
Abstract
The present invention discloses a kind of Chinese medicine composition, and the Chinese medicine composition includes a variety of Chinese medicine composition such as Bungarus Parvus, schefflera arboricola, climbing entada, the monarch drug in a prescription using Bungarus Parvus as full side;Schefflera arboricola, wide muscle rattan, datura flower, adenosma indianum, paniculate swallowwort, Pine Nodular Branch, Chinese ephedra, schizonepeta active pain relieving, climbing entada, the rhizome of davallia, the root of Chinese clematis, the promoting blood circulation soft pulse such as windproof dispelling wind and eliminating dampness, Radix Angelicae Sinensis, safflower, motherwort, are altogether ministerial drug;Radix Aconiti, the sward root of three-nerved spicebush are adjutant etc., each flavour of a drug or dispelling wind and eliminating dampness or promoting blood circulation and removing blood stasis or swelling and pain relieving, all medicine compatibilities, play altogether inducing diaphoresis eliminating evil, swelling and pain relieving, the promoting flow of qi and blood circulation, removing damp-heat, keep away it is dirty sterilization etc. effect, can safely and effectively be used to treat rheumatism.Meanwhile the invention also discloses the preparation method of the plaster containing the Chinese medicine composition and the plaster.
Description
Technical field
It is especially a kind of to use the present invention relates to a kind of plaster being prepared for Chinese medicine composition and using said composition
In the Chinese medicine composition of rheumatism and the rheumatic plaster being prepared using the Chinese medicine composition.
Background technology
Rheumatic, rheumatoid arthritis are a kind of chronic systemic immunity diseases based on arthropathy.Late period is also
Joint deformity can be caused, the lighter causes limbs joint partial function obstacle, and severe one can cause lifelong disability, directly influence patient
Work and viability, seriously endanger the physical and mental health of people, great pain brought to patient.Modern medicine is to this disease
The cause of disease, the mechanism of morbidity do not understand that it is treated mainly with non-steroidal anti-inflammatory class medicine, corticosteroid medication, also with mould still
The antibiotic medicine that element represents, this treatment situation particularly basic hospital and rural area, more aobvious protrusion.This kind of medicine is taken, though
With rear effective very fast, but act on can not be lasting, and particularly in terms of rheumatoid arthritis is treated, its late result more shows nothing
Can be power.On the other hand, these drug side-effects are larger, and are also easy to produce drug resistance, unsuitable long term usage.
The treatment means of inner disease outer treat, easy to use with its, evident in efficacy, the advantages of having no side effect, enjoys patient to favor,
Clinically, have been used for the treatment of rheumatic, rheumatoid arthritis, and obtain the effect of obvious.Traditional black plaster is gone through
Still used till today through 1,100, it was demonstrated that its immortal value, in today that science and technology is with rapid changepl. never-ending changes and improvements, how with modernization
Technology improves the manufacture craft of traditional black plaster, and acquisition is safe and effective, toxic side effect is small, steady quality black plaster is modern black
The only way which must be passed of plaster development.
The content of the invention
A kind of safe and effective, nothing is provided it is an object of the invention to overcome above-mentioned the shortcomings of the prior art
The Chinese medicine composition for being used to treat rheumatism of toxic side effect, steady quality, while present invention also offers use the Chinese medicine group
The rheumatic plaster and the preparation method of the rheumatic plaster that compound is prepared, the preparation method of the rheumatic plaster can gram
Take and react incomplete in traditional handicraft, easily cause the shortcomings of being also easy to produce lead powder dirt in lead residual and production operation, there is operation peace
Complete easy, lower red the characteristics of reacting complete, unleaded residual.
To achieve the above object, the technical scheme taken of the present invention is:A kind of Chinese medicine composition, the Chinese medicine composition contain
There is the component of following parts by weight:
As the preferred embodiment of Chinese medicine composition of the present invention, the Chinese medicine composition contains following parts by weight
Component:
As the preferred embodiment of Chinese medicine composition of the present invention, the Chinese medicine composition contains following parts by weight
Component:
As the preferred embodiment of Chinese medicine composition of the present invention, the Chinese medicine composition contains following parts by weight
Component:
As the preferred embodiment of Chinese medicine composition of the present invention, the Chinese medicine composition contains following parts by weight
Component:
Its raw material for being included of Chinese medicine composition of the present invention, pharmacology analysis are:
Bungarus Parvus:Often use medicine for rheumatism for the traditional Chinese medical science, degrading the channel, only convulsion attack poison, tool analgesia, anti-inflammatory activity, analgesia effect
Fruit is strong compared with morphine, and is not likely to produce tolerance and dependence.
Radix zanthoxyli:The special effect in terms of swelling and pain relieving, tool anti-inflammatory, analgesia, antibacterial activity.
Paniculate swallowwort:Have wind-expelling pain-stopping, removing toxicity for detumescence, the work(of warming and activating meridian, there are calm, analgesic activities.
Wide muscle rattan:There is relaxing tendons and activating collaterals, the work(of wind-expelling pain-stopping, have anti-inflammatory activity.
Safflower:It is invigorate blood circulation, the good medicine of stasis-dispelling and pain-killing, tool antalgic and inflammation relieving is active.
The root of Chinese clematis:It is the good medicine for treating gout, the work(for having dispelling wind and eliminating dampness, there is anti-inflammatory and antalgic, antibacterial bacteriostatic activity.
The root bark of shaggy-fruited dittany:With heat-clearing and damp-drying drug, wind-dispelling removing toxic substances, desinsection is antipruritic the effect of, have antipyretic and antimicrobial antiphlogistic active.
Pterospermi Heterophylli:Unique curative effect with dispelling wind and eliminating dampness, activating blood circulation and reducing swelling, tool analgesia, anti-inflammatory activity.
Cortex acanthopanacis:With scattered wind clearing damp, inducing diuresis for removing edema, the effect of liver and kidney benefiting strengthens the bone, there are obvious analgesic activities.
Soil plus skin:Has the work(of dispelling wind and eliminating dampness.
Radix Angelicae Sinensis:With the effect of adjusting blood, menstruction regulating and pain relieving of enriching blood, hematopoiesis function can be promoted, there is anti-inflammatory and antalgic activity.
Madder:There is dissolving stasis, stop blooding, stimulate the menstrual flow, there is anti-inflammation, antipyretic activity.
Pseudo-ginseng:Has promoting blood circulation and removing blood stasis, hemostasis work(, the activity for having antalgic and inflammation relieving.
Pawpaw:Relaxing tendons and activating collaterals, clearing damp eliminating impediment, tool antalgic and inflammation relieving activity.
Pine Nodular Branch:With dispel pathogenic wind and remove dampness, strengthening the bones and muscles effect.
Schefflera arboricola:Promoting qi circulation and relieving pain, activating blood circulation and reducing swelling, strengthen the bone, tool antalgic and inflammation relieving activity.
Levisticum:With dispelling wind and eliminating dampness, the effect of numbness relieving and pain relieving, has anti-inflammatory and antalgic activity.
Notopterygium root:With dispelling wind and eliminating dampness, the work(of analgesic, has antipyretic-antalgic anti-inflammatory activity.
Datura flower:Has antiasthmatic-antitussive, the work(for spasmolysis of easing pain, tool is calm, eases pain, anti-inflammatory antiallergic activity.
Teasel root:Can filling liver kidney, strengthening the bones and muscles, adjust blood vessels, continue injured, have anti-inflammatory, ease pain, the hemotoncus that disappears activity.
True lacquertree root:Dissipate stasis of blood hemostasis, removing toxic substances.
The root of fangji:Wind-expelling pain-stopping, inducing diuresis for removing edema, there is easing pain and diminishing inflammation effect.
Laggera alata:There is dispelling wind and eliminating dampness, eliminating stasis to subdue swelling, heat-clearing toxin-expelling functions, there is anti-inflammatory activity.
Adenosma indianum:There is preferable anti-inflammatory analgetic effect.
Punctate ardisia herb:Promoting blood circulation for regulating menstruation, dispelling wind and eliminating dampness.
The root of bidentate achyranthes:Filling liver kidney, strengthening the bones and muscles, dispelling stasis of blood and stimulating the menstrual flow, tool anti-inflammatory, antibacterial, analgesic activities.
Climbing entada:Dispelling wind and eliminating dampness, it is promoting blood circulation and removing obstruction in channels, there are anti-inflammatory, antioxidation.
The rhizome of davallia:With analgesic of curing the wound, the effect of The strong bone of kidney tonifying, there is anti-osteoarthritis.
Castor root:Tranquilizing to relieve muscle spasm, wind-dispelling dissipate the stasis of blood.
Hypoglaucous collett yam rhizome:Dampness removing is dispelled turbid, wind expelling stagnation removing, has the effect of anti-inflammatory, antibacterial.
Stropanthus divericatus:Dispelling wind and eliminating dampness, it is clearing and activating the channels and collaterals.
Mistletoe:Wind-damp dispelling, filling liver kidney, strengthening the bones and muscles.
Ergcibe obtusifolia:Dispelling wind clearing damp, relaxing tendons and activating collaterals, swelling and pain relieving, there is anti-inflammatory and antalgic activity.
The fruit of a cubeb litsea tree:Expelling wind and clearing away cold, qi-regulating desinsection, the effect for analgesic of detoxifying, there are analgesia, antifungic action.
Chinese ephedra:Sweating cold dispelling, freeings lung and relieving asthma, inducing diuresis for removing edema.
It is windproof:The effect of with inducing sweat and dispelling exogenous evils, dispelling wind and eliminating dampness, analgesic, there are antipyretic-antalgic, anti-inflammatory activity.
Canton love-pea vine:The effect of with clearing heat and promoting diuresis, blood stasis removing analgesic, there are scavenging hydroxyl, antimicrobial antiphlogistic effect.
Schizonepeta:There is inducing sweat and dispelling exogenous evils, have antipyretic-antalgic anti-inflammatory activity.
Motherwort:With promoting blood circulation for regulating menstruation, inducing diuresis for removing edema, clearing heat and detoxicating work(, there is anti-inflammatory and antalgic activity.
Radix Aconiti Kusnezoffii:Dispelling wind and eliminating dampness, antalgic, have analgesic activities.
Radix Aconiti:Eliminating cold to stop pain, has anti-inflammatory and antalgic activity.
Red lead:External application hygroscopic, removing toxic substances and promoting tissue regeneration.This product is mainly used in plaster, can with vegetable oil chemical combination, to boil plaster
Bodying agent, there is preferable clearing damp to act on.
In addition, the present invention also provide it is a kind of safely and effectively, have no toxic side effect, the plaster of steady quality, the plaster contains
Chinese medicine composition as described above.
The plaster of the present invention, is solely weighed with Bungarus Parvus dispelling wind and eliminating dampness, dredging collateral, dosage, is the in love product of flesh and blood, for full side
Monarch drug in a prescription;Schefflera arboricola, wide muscle rattan, datura flower, adenosma indianum, paniculate swallowwort, Pine Nodular Branch, Chinese ephedra, schizonepeta active pain relieving, climbing entada, bone
Broken benefit, the root of Chinese clematis, the promoting blood circulation soft pulse such as windproof dispelling wind and eliminating dampness, Radix Angelicae Sinensis, safflower, motherwort, are altogether ministerial drug;Remaining punctate ardisia herb, six ribs
Chrysanthemum etc. or dehumidifying carry poison or soft muscle, are also ministerial drug;Radix Aconiti, the sward root of three-nerved spicebush are very toxic, enter plaster and are fried through high temperature, are stayed
Detoxification is imitated, warming meridians and promoting circulation of qi analgesic, is adjutant;Levisticum, notopterygium root, schizonepeta, root of bidentate achyranthes priming or up or down, or it is inner or outer, do not reach nowhere
To make medicine.Though flavour of a drug are more, and monarch law is strict and impartial;Monarch, all property of medicine have slow high, and are had great disparity in numerical strength than class, so as to
Special envoy, assistant function emerge from.
As the preferred embodiment of plaster of the present invention, the plaster also contains vegetable oil and red lead.The present invention's
Plaster substrate is made up of two parts, and a part is the lead orthoplumbate formation in unrighted acid and red lead in vegetable oil
Divalence lead soap, it is a kind of surfactant of water-in-oil type, and another part is then the thickening thing of remaining vegetable oil being oxygenized polymerization,
Lead soap can increase the permeability of skin as surfactant and promote the absorption of Passive diffusion.The plaster base of the present invention
Matter, nerve endings can be stimulated to increase body circulation, and then play the transmission for accelerating medicine and promoting blood circulation effect.Drug Percutaneous Absorption,
Body circulation is entered to produce general action by blood vessel or lymphatic vessel in tissue.Drug absorption is first without liver, no liver
Cross effect;Liver is not damaged, does not lower drug effect;It is evident in efficacy.
As the more preferably embodiment of plaster of the present invention, the plaster also contains the composition of following parts by weight:Plant
13300~15300 parts of thing oil, 3550~5760 parts of red lead.
As the preferred embodiment of plaster of the present invention, the plaster also contains the composition of following parts by weight:Plant
Oily 13300 parts, 3550 parts of red lead.
As the preferred embodiment of plaster of the present invention, the plaster also contains the composition of following parts by weight:Plant
Oily 15300 parts, 5760 parts of red lead.
As the preferred embodiment of plaster of the present invention, the plaster also contains the composition of following parts by weight:Plant
Oily 14300 parts, 5710 parts of red lead.
As the preferred embodiment of plaster of the present invention, the plaster also contains the composition of following parts by weight:Plant
Oily 14300 parts, 4004 parts of red lead.
As the preferred embodiment of plaster of the present invention, the vegetable oil be peanut oil, sesame oil, cottonseed oil, soya-bean oil,
At least one of rapeseed oil, oil extracted from rice husks.
As the more preferably embodiment of plaster of the present invention, the vegetable oil is peanut oil.Tempered using peanut oil
Plaster there is the characteristics of pitch-black bright, property of medicine of outward appearance easily penetrates into skin, and the plaster viscosity refined and the docile and obedient degree with skin
Very well, be affixed on that skin takes off rise and it is difficult for drop-off.Though sesame oil, cottonseed oil, soya-bean oil, rapeseed oil, tea-seed oil, oil extracted from rice husks also can use
In tempering plaster, but foam is easily produced during cream refining, during lower red reaction, pot domestic demand reserves larger space, otherwise easy overflow
Take the dish out of the pot, potential safety hazard be present.Meanwhile the oil refining time of sesame oil, cottonseed oil, soya-bean oil, rapeseed oil, tea-seed oil, oil extracted from rice husks is compared with peanut
The length of oil, within the identical oil refining time, the plaster of refining or to stick at skin not easily shifted, or have plaster residual.
Finally, the present invention also provides a kind of simple and safe operation, the lower red plaster preparation side for reacting complete, unleaded residual
Method, in order to achieve this, the technical scheme that the present invention takes is:A kind of preparation method of plaster as described above, including following step
Suddenly:
(1) pre-process:The Chinese medicine after coarse crushing is weighed, is put in pot, takes vegetable oil to obtain medicinal material with immersion medicinal material in pot is put
With the mixture A of vegetable oil;
(2) spice extracts:A is heated, until medicinal material is fried withered, the dregs of a decoction are filtered off after explosive, the oil gone after the dregs of a decoction is medicine oil B;
(3) refine oil:Medicine oil B is continued to temper, until oil bloom are assembled to pot center, medicine oil is refined to beading of dripping, you can is stopped
Only temper, obtain medicine oil C;
(4) red oil mixing:Taken out in right amount from medicine oil C, obtain medicine oil D, put in tank, added red lead and stir, obtain
Red oil mixture E;Remaining medicine oil is F after medicine oil C takes out medicine oil D;
(5) it is red under:The oily F that gets it filled is heated, and is added red oil mixture E, is obtained reactant G;
(6) react:Reactant G is continued into heating stirring, cream can be gone out by stirring into sticky lotion, obtain lotion H;
(7) release fire-toxin:Lotion H is put into soak in water at room temperature and released fire-toxin, obtains lotion I;
(8) stand applies section:Machine stand on lotion I is applied, plaster is can obtain after section.
As the preferred embodiment of the preparation method of plaster of the present invention, the described method comprises the following steps:
(1) pre-process:The Chinese medicine after coarse crushing is weighed, is put in pot, takes vegetable oil to be obtained with immersion medicinal material 7 days in pot are put
The mixture A of medicinal material and vegetable oil;
(2) spice extracts:A is heated to 190 DEG C~220 DEG C, keeping temperature, until spice is fried withered, medicine is filtered off after explosive
Slag, the oil gone after the dregs of a decoction are medicine oil B;
(3) refine oil:Medicine oil B is heated to 250 DEG C~320 DEG C, keeping temperature, continues to temper 2~7 hours, until oil bloom
Assemble to pot center, medicine oil is refined to beading of dripping, you can stopping is tempered, and obtains medicine oil C;
(4) red oil mixing:1/5~1/3 is taken out from medicine oil C, medicine oil D is obtained, puts in feed pot, it is equal to add red lead stirring
It is even, obtain red oil mixture E;Remaining medicine oil is F after medicine oil C takes out medicine oil D;
(5) it is red under:Oily F heating DEG C get it filled to 250 DEG C~300 DEG C, adds red oil mixture E, lower red time control is 0.5
~1h, and be stirred continuously, obtain reactant G;
(6) react:Reactant G is continued to be heated to 250 DEG C~300 DEG C, continues 0.5~3h of reaction, and is stirred continuously, is stirred
It can go out cream into sticky lotion, obtain lotion H;
(7) release fire-toxin:Lotion H is put into soak in water at room temperature and released fire-toxin, a water is changed daily, is taken out after seven days,
Obtain lotion I;
(8) stand applies section:Machine stand on lotion I is applied, plaster is can obtain after section.
As the preferred embodiment of the preparation method of plaster of the present invention, the described method comprises the following steps:
(1) pre-process:The Chinese medicine after coarse crushing is weighed, is put in pot, takes vegetable oil to be obtained with immersion medicinal material 7 days in pot are put
The mixture A of medicinal material and vegetable oil;
(2) spice extracts:A is heated to 200 DEG C, keeping temperature, until spice is fried withered, the dregs of a decoction is filtered off after explosive, remove medicine
Oil after slag is medicine oil B;
(3) refine oil:Medicine oil B is heated to 270 DEG C, keeping temperature, continues to temper 6 hours, you can stopping is tempered, and obtains medicine
Oily C;
(4) red oil mixing:1/4 part is taken out from medicine oil C, medicine oil D is obtained, puts in feed pot, red lead is added and stirs,
Obtain red oil mixture E;Remaining medicine oil is F after medicine oil C takes out medicine oil D;
(5) it is red under:The oily F that gets it filled is heated to 260 DEG C, adds red oil mixture E, and lower red time control is in 0.5h, and constantly
Stirring, obtains reactant G;
(6) react:Reactant G is continued to be heated to 285 DEG C, continues 1~2h of reaction, and is stirred continuously, is stirred into sticky
Lotion can go out cream, obtain lotion H;
(7) release fire-toxin:Lotion H is put into soak in water at room temperature and released fire-toxin, a water is changed daily, is taken out after seven days,
Obtain lotion I;
(8) stand applies section:Machine stand on lotion I is applied, plaster is can obtain after section.
Present invention also offers Chinese medicine composition as described above in the medicine for preparing treatment osteoproliferation, soft tissue injury
Purposes in thing.In Chinese medicine composition of the present invention, each flavour of a drug or dispelling wind and eliminating dampness or promoting blood circulation and removing blood stasis or swelling and pain relieving, all medicines
Compatibility, play altogether inducing diaphoresis eliminating evil, swelling and pain relieving, the promoting flow of qi and blood circulation, removing damp-heat, keep away it is dirty sterilization etc. effect, be treatment rheumatism joint
Inflammation, rheumatoid arthritis, sciatica, osteoproliferation, soft tissue injury, the good prescription of wound swelling and pain.
Plaster of the present invention, the Chinese medicine composition containing the special formulation, with reference to the specific plaster substrate, energy
Enough effective for treatment rheumatic arthritis, rheumatoid arthritis, sciatica, osteoproliferation, soft tissue injury, wound
Swelling and pain etc., there is the effect of notable.
Plaster of the present invention, outer patch part 2h -6h interior energies substantially increase local blood flow and the operating speed of biochemical substances
Degree.Transdermal absorption, joint and surrounding tissue are directly acted on, follow the blood of synovia in capsular ligament, capsular ligament, synovium of joint
Ring is promoted, and reaches dispeling wind and dehumidification, promoting blood circulation and removing blood stasis, softening and resolving hard mass, the effect of anti-inflammatory analgetic, be effective against osteoproliferation,
Rheumatism, rheumatoid arthritis, action effect are obvious.
In addition, plaster of the present invention, can effectively facilitate blood circulation, accelerate the reparation and regeneration of articular chondrocytes.
Local topical, phagocyte can be made all to be strengthened on quality and quantity, accelerate the metabolism of local organization, mitigate inflammation
Or eliminate, be advantageous to nutrition of the joint fluid to articular chondrocytes, promotion is metabolism-normalizing, and detumescence, anti-inflammatory, analgesic activity are strong.
Acute soft tissue traumatic injury is treated, curative effect is rapid, has obvious analgesic, detumescence effect, can recover normal typically in 2-3 days
Live and work, cured in one week.In terms of chronic soft tissue injury is treated, can relaxing tendons and activating collaterals, it is promoting blood circulation and removing blood stasis, detumescence stop
Bitterly, dispelling wind and eliminating dampness, it is curative for effect.
The preparation method of plaster of the present invention, traditional handicraft is improved with up to date technics, using wet method
Lower red lower folk prescription formula, during reducing lower pellet, red lead caking phenomenon, the finer and smoother light of plaster tempered.Meanwhile wet method
Lower pellet makes red oil reaction more complete, reduces the residual of red lead in lotion, makes plaster more safe and effective.
Embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention
It is described further.
Embodiment 1
A kind of embodiment of plaster of the present invention, plaster described in the present embodiment contain Chinese medicine composition, vegetable oil and red lead;
The Chinese medicine composition contains the composition of following parts by weight:
The vegetable oil is peanut oil, and the parts by weight of the vegetable oil are 15300 parts;
The parts by weight of the red lead are 5760 parts.
Plaster is prepared with the following method described in the present embodiment:
(1) pre-process:The Chinese medicine after coarse crushing is weighed, is put in pot, takes vegetable oil to be soaked seven days with immersion medicinal material in pot is put
Afterwards, the mixture A of medicinal material and vegetable oil is obtained;
(2) spice extracts:A is heated to 220 DEG C, keeping temperature, until medicinal material fry it is withered, it is fried it is good after filter off the dregs of a decoction, remove slag
Oil afterwards is medicine oil B;
(3) refine oil:Medicine oil B is heated to 250 DEG C, keeping temperature continues to temper 7 hours, until oil bloom are poly- to pot center
Collection, medicine oil are refined to beading of dripping, you can stopping is tempered, and obtains medicine oil C;
(4) red oil mixing:1/5 medicine oil is taken out from medicine oil C, medicine oil D is obtained, puts in tank, red lead is added and stirs,
Obtain red oil mixture E;Remaining medicine oil is F after medicine oil C takes out medicine oil D;
(5) it is red under:The oily F that gets it filled is heated to 260 DEG C, adds red oil mixture E, and the lower red time will be 0.5h, obtain reactant
G;
(6) react:After lower pellet, reactant G is continued to be heated to 280 DEG C, and is stirred continuously, continue reaction 2 hours,
Stir into sticky lotion and go out cream, obtain lotion H;
(7) release fire-toxin:Lotion H is put into soak seven days in water at room temperature and released fire-toxin, and changes a water daily, is obtained
Lotion I;
(8) stand applies section:Machine stand on lotion I is applied, plaster is can obtain after section.
Embodiment 2
A kind of embodiment of plaster of the present invention, plaster described in the present embodiment contain Chinese medicine composition, vegetable oil and red lead;
The Chinese medicine composition contains the composition of following parts by weight:
The vegetable oil is peanut oil, and the parts by weight of the vegetable oil are 13300 parts;
The parts by weight of the red lead are 3550 parts.
Plaster is prepared with the following method described in the present embodiment:
(1) pre-process:The Chinese medicine after coarse crushing is weighed, is put in pot, takes vegetable oil to be soaked seven days with immersion medicinal material in pot is put
Afterwards, the mixture A of medicinal material and vegetable oil is obtained;
(2) spice extracts:A is heated to 200 DEG C, keeping temperature, until medicinal material fry it is withered, it is fried it is good after filter off the dregs of a decoction, remove slag
Oil afterwards is medicine oil B;
(3) refine oil:Medicine oil B is heated to 320 DEG C, keeping temperature continues to temper 2 hours, until oil bloom are poly- to pot center
Collection, medicine oil are refined to beading of dripping, you can stopping is tempered, and obtains medicine oil C;
(4) red oil mixing:1/3 medicine oil is taken out from medicine oil C, medicine oil D is obtained, puts in tank, red lead is added and stirs,
Obtain red oil mixture E;Remaining medicine oil is F after medicine oil C takes out medicine oil D;
(5) it is red under:The oily F that gets it filled is heated to 250 DEG C, adds red oil mixture E, and the lower red time will be 1h, obtain reactant G;
(6) react:After lower pellet, reactant G is continued to be heated to 250 DEG C, and is stirred continuously, continue reaction 3 hours,
Stir into sticky lotion and go out cream, obtain lotion H;
(7) release fire-toxin:Lotion H is put into soak seven days in water at room temperature and released fire-toxin, and changes a water daily, is obtained
Lotion I;
(8) stand applies section:Machine stand on lotion I is applied, plaster is can obtain after section.
Embodiment 3
A kind of embodiment of plaster of the present invention, plaster described in the present embodiment contain Chinese medicine composition, vegetable oil and red lead;
The Chinese medicine composition contains the composition of following parts by weight:
The vegetable oil is sesame oil, and the parts by weight of the vegetable oil are 14300 parts;
The parts by weight of the red lead are 5710 parts.
Plaster is prepared with the following method described in the present embodiment:
(1) pre-process:The Chinese medicine after coarse crushing is weighed, is put in pot, takes vegetable oil to be soaked seven days with immersion medicinal material in pot is put
Afterwards, the mixture A of medicinal material and vegetable oil is obtained;
(2) spice extracts:A is heated to 220 DEG C, keeping temperature, until medicinal material fry it is withered, it is fried it is good after filter off the dregs of a decoction, remove slag
Oil afterwards is medicine oil B;
(3) refine oil:Medicine oil B is heated to 300 DEG C, keeping temperature continues to temper 4 hours, until oil bloom are poly- to pot center
Collection, medicine oil are refined to beading of dripping, you can stopping is tempered, and obtains medicine oil C;
(4) red oil mixing:1/4 medicine oil is taken out from medicine oil C, medicine oil D is obtained, puts in tank, red lead is added and stirs,
Obtain red oil mixture E;Remaining medicine oil is F after medicine oil C takes out medicine oil D;
(5) it is red under:The oily F that gets it filled is heated to 300 DEG C, adds red oil mixture E, and the lower red time will be 0.5h, obtain reactant
G;
(6) react:After lower pellet, reactant G is continued to be heated to 300 DEG C, and be stirred continuously, it is small to continue reaction 1.5
When, stir into sticky lotion and go out cream, obtain lotion H;
(7) release fire-toxin:Lotion H is put into soak seven days in water at room temperature and released fire-toxin, and changes a water daily, is obtained
Lotion I;
(8) stand applies section:Machine stand on lotion I is applied, plaster is can obtain after section.
Embodiment 4
A kind of embodiment of plaster of the present invention, plaster described in the present embodiment contain Chinese medicine composition, vegetable oil and red lead;
The Chinese medicine composition contains the composition of following parts by weight:
The vegetable oil is cottonseed oil, and the parts by weight of the vegetable oil are 14300 parts;
The parts by weight of the red lead are 4290 parts.
Plaster is prepared with the following method described in the present embodiment:
(1) pre-process:The Chinese medicine after coarse crushing is weighed, is put in pot, takes vegetable oil to be soaked seven days with immersion medicinal material in pot is put
Afterwards, the mixture A of medicinal material and vegetable oil is obtained;
(2) spice extracts:A is heated to 190 DEG C, keeping temperature, until medicinal material fry it is withered, it is fried it is good after filter off the dregs of a decoction, remove slag
Oil afterwards is medicine oil B;
(3) refine oil:Medicine oil B is heated to 270 DEG C, keeping temperature continues to temper 6 hours, until oil bloom are poly- to pot center
Collection, medicine oil are refined to beading of dripping, you can stopping is tempered, and obtains medicine oil C;
(4) red oil mixing:1/4 medicine oil is taken out from medicine oil C, medicine oil D is obtained, puts in tank, red lead is added and stirs,
Obtain red oil mixture E;Remaining medicine oil is F after medicine oil C takes out medicine oil D;
(5) it is red under:The oily F that gets it filled is heated to 270 DEG C, adds red oil mixture E, and the lower red time will be 0.5h, obtain reactant
G;
(6) react:After lower pellet, reactant G is continued to be heated to 290 DEG C, and is stirred continuously, continue reaction 1 hour,
Stir into sticky lotion and go out cream, obtain lotion H;
(7) release fire-toxin:Lotion H is put into soak seven days in water at room temperature and released fire-toxin, and changes a water daily, is obtained
Lotion I;
(8) stand applies section:Machine stand on lotion I is applied, plaster is can obtain after section.
Embodiment 5
A kind of embodiment of plaster of the present invention, plaster described in the present embodiment contain Chinese medicine composition, vegetable oil and red lead;
The Chinese medicine composition contains the composition of following parts by weight:
The vegetable oil is peanut oil, and the parts by weight of the vegetable oil are 14300 parts;
The parts by weight of the red lead are 4004 parts.
Plaster is prepared with the following method described in the present embodiment:
(1) pre-process:The Chinese medicine after coarse crushing is weighed, is put in pot, takes vegetable oil to be soaked seven days with immersion medicinal material in pot is put
Afterwards, the mixture A of medicinal material and vegetable oil is obtained;
(2) spice extracts:A is heated to 200 DEG C, keeping temperature, until medicinal material fry it is withered, it is fried it is good after filter off the dregs of a decoction, remove slag
Oil afterwards is medicine oil B;
(3) refine oil:Medicine oil B is heated to 270 DEG C, keeping temperature continues to temper 6 hours, until oil bloom are poly- to pot center
Collection, medicine oil are refined to beading of dripping, you can stopping is tempered, and obtains medicine oil C;
(4) red oil mixing:1/4 medicine oil is taken out from medicine oil C, medicine oil D is obtained, puts in tank, red lead is added and stirs,
Obtain red oil mixture E;Remaining medicine oil is F after medicine oil C takes out medicine oil D;
(5) it is red under:The oily F that gets it filled is heated to 260 DEG C, adds red oil mixture E, and the lower red time will be 0.5h, obtain reactant
G;
(6) react:After lower pellet, reactant G is continued to be heated to 285 DEG C, and be stirred continuously, it is small to continue reaction 1.5
When, stir into sticky lotion and go out cream, obtain lotion H;
(7) release fire-toxin:Lotion H is put into soak seven days in water at room temperature and released fire-toxin, and changes a water daily, is obtained
Lotion I;
(8) stand applies section:Machine stand on lotion I is applied, rheumatic plaster is can obtain after section.
Embodiment 6
Select influence of the different vegetable oil to plaster performance
The present embodiment investigates the influence for selecting different vegetable oil to plaster final performance, sets test group 1~7 respectively,
It is the composition and content of Chinese medicine composition, the content of vegetable oil, red in test group 1~7 in addition to vegetable oil is different into component selections
The all same such as process conditions in red content and preparation method, the respectively color of the gained plaster of testing experiment group 1~7 and pressing
Performance, plant oil component and test result selected by test group 1~7 are shown in Table 1.
The different plant oil components of table 1 are to plaster performance impact result of the test
Note:+++ significantly ++ it is more significant+it is visible ± slightly see
Can be seen that by the result of table 1, during using peanut oil, gained plaster outward appearance is pitch-black shinny, and the viscosity of gained plaster with
The docile degree of skin is preferable.
Embodiment 7
Effect test of the plaster of the present invention in terms of dispeling wind and dehumidification dispeling wind and dehumidification, swelling and pain relieving
1st, clinical observation experiment of the plaster of the present invention in treatment rheumatism, rheumatoid arthritis
The plaster treatment rheumatoid arthritis being prepared using the embodiment of the present invention 5, test method:Randomly select class wind
Wet arthritis case 140 is used as subjects, is selected respectively according to painful area in big vertebra, Huantiao, committee, chengshan, Yanglingquan
Etc., heating and softening sticks.12-36h is used per note.Each position rotation is used alternatingly, and prevents and treats exanthemv.Patient is detected respectively
Pretherapy and post-treatment morning stiffness number of cases, arthralgia number of cases, tenderness joint number, tenderness index, swollen joint number, swelling index, CRP, knot
Fruit is shown in Table 2.
2 pretherapy and post-treatment clinical symptoms of table contrast
Morning stiffness number of cases | Arthralgia number of cases | Tenderness articular index | Swollen joint index | CRP(ug/h) | |
Before treatment | 124 | 132 | 17.85±8.52 | 9.95±5.28 | 42.38±15.22 |
After treatment | 35 | 46 | 9.25±6.24 | 4.25±5.12 | 22.42±14.76 |
It can be seen that by the result of table 2, when the plaster that the embodiment of the present invention is prepared is used to treat rheumatoid arthritis, treatment
Afterwards compared with pre-treatment, the morning stiffness number of cases of patient, arthralgia number of cases, tenderness joint number, tenderness index, swollen joint number, swelling
Index, CRP are achieved and are obviously improved.
Other embodiment is respectively provided with same effect in the present invention, will not be repeated here.
2nd, the clinical observation experiment of plaster treatment soft tissue injury of the present invention
It is grouped using random controls method, using shangshi zhitong plaster, shangshi zhitong gao of the prior art as control group, with the embodiment of the present invention 5
The plaster being prepared is as test group.Wherein, the shangshi zhitong plaster, shangshi zhitong gao of the prior art is by Shangshi Zhitong liquid extraction, water
Poplar acid methyl esters, menthol, borneol, camphor, liguidamber resinoid and belladonna liquid extract composition.Above-mentioned Shangshi Zhitong liquid extraction is by giving birth to
Radix aconiti agrestis, Radix Aconiti, frankincense, myrrh, Semen Strychni, cloves, Chinese cassia tree, schizonepeta, windproof, geranium wilfordii, cortex periplocae, centella, bone are broken
Benefit, the root of Dahurain angelica, kaempferia galamga, rhizoma zingiberis are made.
Test method:Control group and test group randomly select 161 soft tissue injury patients respectively, and control group uses affection by dampness
Pain relieving ointment is affixed on affected part, and test group spreads on affected part, control group and test group are every using the plaster of the present invention after pico- heating and softening
Patch uses 12-36h, pastes 7 days altogether, clinical observation result is as shown in table 3.
The plaster treatment wound swelling and pain effect of the present invention of table 3
Group | Cure | It is effective | Effectively | It is invalid | It is total effective |
Control group | 40% | 20% | 18% | 22% | 78% |
Test group | 56% | 22% | 12% | 10% | 90% |
Plaster obtained by other embodiments of the invention has equal effect, will not be repeated here.As seen from the experiment, adopt
When treating soft tissue injury with the test group of plaster of the present invention, the pain of patient has obvious decrease, and total effective rate is up to
90%.
3rd, the effect test of plaster treatment sciatica of the present invention
Test group and control group are set respectively, and control group uses shangshi zhitong plaster, shangshi zhitong gao of the prior art, and test group is using this
The plaster that inventive embodiments 5 are prepared.
Test method:Control group and test group respectively randomly select 158 sciatica patients, the patient of control group
Treated using shangshi zhitong plaster, shangshi zhitong gao of the prior art, the patient of test group is treated using plaster of the present invention, is seen respectively
The effect after treatment is examined, the results are shown in Table shown in 4.
The effect of the plaster treatment sciatica of the present invention of table 4
Group | Patients with mild is efficient | Moderate patient is efficient | Severe patient is efficient |
Test group | 88.9% | 94.8% | 94.6% |
Control group | 90.6% | 77.3% | 86.7% |
The plaster that other embodiments of the invention are prepared has effect similarly to Example 5, will not be repeated here.
4th, the effect test of plaster treatment osteoproliferation of the present invention
Test group and control group are set respectively, and test group uses the bone of prior art using plaster of the invention, control group
Pain patch cream.Wherein, the bone lead to emplastrum be by ergcibe obtusifolia, Chinese ephedra, Radix Angelicae Sinensis, rhizoma zingiberis, the root of Dahurain angelica, caulis piperis futokadsurae, frankincense, pseudo-ginseng, turmeric,
Capsicum, camphor, cinnamon oil, invaluable and menthol are made.
Test method:Control group and test group randomly select 124 Osteoarthritis respectively, and control group is using existing
The bone pain medicine plaster patch of technology is affixed on affected part using the plaster of the present invention, often pastes and use 12-36h, paste 7 altogether in affected part, test group
My god.After treatment, the therapeutic effect of two groups of statistics, it the results are shown in Table shown in 5.
The effect of the plaster treatment osteoproliferation of the present invention of table 5
Group | Clinic control | It is effective | Effectively | It is invalid | It is total effective |
Test group | 3.81% | 53.19% | 29.74% | 13.26% | 86.74% |
Control group | 3.94% | 32.03% | 39.22% | 24.81% | 75.19% |
It can be seen that the total effective rate of test group reaches 86.74%, is significantly higher than control group by the result of table 5.The present invention other
The plaster that embodiment is prepared has effect similarly to Example 5, will not be repeated here.
5th, the clinical effectiveness experiment of Minor articulus synovitis is treated
Small joints in lumbar spine synovitis patient 137 is randomly selected, the plaster obtained using the embodiment of the present application 5 is heated slightly
Softening, spreads on affected part, and deposited often paste uses 12-36h, after pasting 7 days altogether, counts therapeutic effect, the results are shown in Table shown in 6.
The effect of the plaster treatment Minor articulus synovitis of the present invention of table 6
Cure | It is effective | Effectively | It is invalid | It is total effective |
36.99% | 40.87% | 17.52% | 4.38% | 95.62% |
It can be seen that by the result of table 6, plaster of the invention can effectively treat Minor articulus synovitis, and effective percentage is up to
95.62%.The plaster that other embodiments of the invention are prepared has effect similarly to Example 5, will not be repeated here.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than the present invention is protected
The limitation of scope is protected, although being explained in detail with reference to preferred embodiment to the present invention, one of ordinary skill in the art should
Understand, technical scheme can be modified or equivalent substitution, without departing from the essence of technical solution of the present invention
And scope.
Claims (11)
1. a kind of Chinese medicine composition, it is characterised in that the Chinese medicine composition contains the component of following parts by weight:
2. Chinese medicine composition as claimed in claim 1, it is characterised in that the Chinese medicine composition contains the group of following parts by weight
Point:
3. Chinese medicine composition as claimed in claim 1, it is characterised in that the Chinese medicine composition contains the group of following parts by weight
Point:
4. Chinese medicine composition as claimed in claim 3, it is characterised in that the Chinese medicine composition contains the group of following parts by weight
Point:
5. Chinese medicine composition as claimed in claim 4, it is characterised in that the Chinese medicine composition contains the group of following parts by weight
Point:
A kind of 6. plaster containing the Chinese medicine composition as described in any one of Claims 1 to 5.
7. plaster as claimed in claim 6, it is characterised in that the plaster also contains the composition of following parts by weight:Vegetable oil
13300~15300 parts, 3550~5760 parts of red lead.
8. a kind of preparation method of plaster as claimed in claims 6 or 7, it is characterised in that comprise the following steps:
(1) pre-process:The Chinese medicine after coarse crushing is weighed, is put in pot, takes vegetable oil to obtain medicinal material and plant with immersion medicinal material in pot is put
The mixture A of thing oil;
(2) spice extracts:A is heated, until medicinal material is fried withered, the dregs of a decoction are filtered off after explosive, the oil gone after the dregs of a decoction is medicine oil B;
(3) refine oil:Medicine oil B is continued to temper, until oil bloom are assembled to pot center, medicine oil is refined to beading of dripping, you can stopping is endured
Refining, obtains medicine oil C;
(4) red oil mixing:Taken out in right amount from medicine oil C, obtain medicine oil D, put in tank, added red lead and stir, obtain red oil
Mixture E;Remaining medicine oil is F after medicine oil C takes out medicine oil D;
(5) it is red under:The oily F that gets it filled is heated, and is added red oil mixture E, is obtained reactant G;
(6) react:Reactant G is continued into heating stirring, cream can be gone out by stirring into sticky lotion, obtain lotion H;
(7) release fire-toxin:Lotion H is put into soak in water at room temperature and released fire-toxin, obtains lotion I;
(8) stand applies section:Machine stand on lotion I is applied, plaster is can obtain after section.
9. the preparation method of plaster as claimed in claim 8, it is characterised in that the described method comprises the following steps:
(1) pre-process:The Chinese medicine after coarse crushing is weighed, is put in pot, takes vegetable oil to obtain medicinal material with immersion medicinal material 7 days in pot are put
With the mixture A of vegetable oil;
(2) spice extracts:A is heated to 190 DEG C~220 DEG C, keeping temperature, until spice is fried withered, the dregs of a decoction is filtered off after explosive, are gone
Oil after the dregs of a decoction is medicine oil B;
(3) refine oil:Medicine oil B is heated to 250 DEG C~320 DEG C, keeping temperature, continues to temper 2~7 hours, until oil bloom are to pot
Center aggregation, medicine oil are refined to beading of dripping, you can stopping is tempered, and obtains medicine oil C;
(4) red oil mixing:1/5~1/3 is taken out from medicine oil C, medicine oil D is obtained, puts in feed pot, red lead is added and stirs,
Obtain red oil mixture E;Remaining medicine oil is F after medicine oil C takes out medicine oil D;
(5) it is red under:Oily F heating DEG C get it filled to 250 DEG C~300 DEG C, adds red oil mixture E, lower red time control 0.5~
1h, and be stirred continuously, obtain reactant G;
(6) react:Reactant G is continued to be heated to 250 DEG C~300 DEG C, continues 0.5~3h of reaction, and is stirred continuously, is stirred into viscous
Thick lotion can go out cream, obtain lotion H;
(7) release fire-toxin:Lotion H is put into soak in water at room temperature and released fire-toxin, a water is changed daily, takes out, obtain after seven days
Lotion I;
(8) stand applies section:Machine stand on lotion I is applied, plaster is can obtain after section.
10. the preparation method of plaster as claimed in claim 9, it is characterised in that the described method comprises the following steps:
(1) pre-process:The Chinese medicine after coarse crushing is weighed, is put in pot, takes vegetable oil to obtain medicinal material with immersion medicinal material 7 days in pot are put
With the mixture A of vegetable oil;
(2) spice extracts:A is heated to 200 DEG C, keeping temperature, until spice is fried withered, the dregs of a decoction are filtered off after explosive, after removing the dregs of a decoction
Oil be medicine oil B;
(3) refine oil:Medicine oil B is heated to 270 DEG C, keeping temperature, continues to temper 6 hours, you can stopping is tempered, and obtains medicine oil C;
(4) red oil mixing:1/4 part is taken out from medicine oil C, medicine oil D is obtained, puts in feed pot, red lead is added and stirs, obtain
Red oil mixture E;Remaining medicine oil is F after medicine oil C takes out medicine oil D;
(5) it is red under:The oily F that gets it filled is heated to 260 DEG C, adds red oil mixture E, and lower red time control is stirred continuously in 0.5h,
Obtain reactant G;
(6) react:Reactant G is continued to be heated to 285 DEG C, continues 1~2h of reaction, and is stirred continuously, stirs into sticky lotion
Cream can be gone out, obtain lotion H;
(7) release fire-toxin:Lotion H is put into soak in water at room temperature and released fire-toxin, a water is changed daily, takes out, obtain after seven days
Lotion I;
(8) stand applies section:Machine stand on lotion I is applied, plaster is can obtain after section.
11. one kind Chinese medicine composition as described in any one of Claims 1 to 5 is treating osteoproliferation, soft tissue damage for preparing
Purposes in the medicine of wound.
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110478408A (en) * | 2019-09-17 | 2019-11-22 | 王同德 | Iliacus film restores therapy |
CN111053871A (en) * | 2019-11-06 | 2020-04-24 | 湖南经顺昌医疗用品有限公司 | Plaster for treating gout, rheumatism and rheumatoid disease and production method thereof |
CN115554356A (en) * | 2022-11-07 | 2023-01-03 | 广东罗浮山国药股份有限公司 | Traditional Chinese medicine composition, plaster containing traditional Chinese medicine composition and preparation method of plaster |
CN115737741A (en) * | 2022-11-18 | 2023-03-07 | 广东罗浮山国药股份有限公司 | Application of Luoshan rheumatism plaster in preparing medicine for treating peripheral neuritis by external acupoint administration |
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CN104352812A (en) * | 2014-10-28 | 2015-02-18 | 青岛市市立医院 | Black plaster for curing rheumatic arthritis and preparation method thereof |
CN105748950A (en) * | 2014-12-16 | 2016-07-13 | 青岛市黄岛区中医医院 | Black plaster for treating rheumatoid arthritis, and preparation method thereof |
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CN104352812A (en) * | 2014-10-28 | 2015-02-18 | 青岛市市立医院 | Black plaster for curing rheumatic arthritis and preparation method thereof |
CN105748950A (en) * | 2014-12-16 | 2016-07-13 | 青岛市黄岛区中医医院 | Black plaster for treating rheumatoid arthritis, and preparation method thereof |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110478408A (en) * | 2019-09-17 | 2019-11-22 | 王同德 | Iliacus film restores therapy |
CN111053871A (en) * | 2019-11-06 | 2020-04-24 | 湖南经顺昌医疗用品有限公司 | Plaster for treating gout, rheumatism and rheumatoid disease and production method thereof |
CN115554356A (en) * | 2022-11-07 | 2023-01-03 | 广东罗浮山国药股份有限公司 | Traditional Chinese medicine composition, plaster containing traditional Chinese medicine composition and preparation method of plaster |
CN115554356B (en) * | 2022-11-07 | 2023-11-14 | 广东罗浮山国药股份有限公司 | Traditional Chinese medicine composition, plaster containing traditional Chinese medicine composition and preparation method of plaster |
CN115737741A (en) * | 2022-11-18 | 2023-03-07 | 广东罗浮山国药股份有限公司 | Application of Luoshan rheumatism plaster in preparing medicine for treating peripheral neuritis by external acupoint administration |
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Application publication date: 20171201 |