CN107402273B - Automatic sampling assembly and three-dimensional automatic sampling system - Google Patents
Automatic sampling assembly and three-dimensional automatic sampling system Download PDFInfo
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- CN107402273B CN107402273B CN201710742150.3A CN201710742150A CN107402273B CN 107402273 B CN107402273 B CN 107402273B CN 201710742150 A CN201710742150 A CN 201710742150A CN 107402273 B CN107402273 B CN 107402273B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/24—Automatic injection systems
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
- G01N2030/201—Injection using a sampling valve multiport valves, i.e. having more than two ports
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- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
An automatic sampling assembly for mounting on a sampling assembly fixture of an automatic sampling system, the automatic sampling assembly comprising: the device comprises a tension spring fixing plate, two tension springs, a guide rail, a sliding block, a connecting block, a bottle pressing block and a sampling needle seat, wherein the connecting block is fixedly connected with a sampling assembly fixing part, and the sliding block and the sampling needle seat are respectively fixed on the connecting block; the guide rail is arranged on the sliding block in a penetrating way, so that the guide rail and the sliding block form a sliding structure; the tension spring fixing plate is fixed at the upper end of the guide rail, and the bottle pressing block is fixed at the lower end of the guide rail; the two tension springs are respectively arranged at two sides of the guide rail, are arranged between the tension spring fixing plate and the connecting block, and are in a stretched state under the action of the tension spring fixing plate and the connecting block; a sampling needle is fixed on the sampling needle seat. The automatic sampling assembly can quickly and reasonably press the sample bottle to realize sampling, and the sampling needle can be quickly separated from the sample bottle.
Description
Technical Field
The present invention relates to an automatic sampling system, and more particularly, to an automatic sampling assembly and a three-dimensional automatic sampling system including the same.
Background
In the fields of biology, chemistry, medical treatment, chemical industry and the like, along with the development of automation technology, an automatic sampling system gradually replaces manual sampling, and becomes one of key links for acquiring samples. With an automatic sampling system, a user may complete automatic acquisition of a certain amount of sample from a particular sample container, and then transfer the sample to a target container such as a mixer, waiting for further detection of the sample, and the like.
Such as a chromatographic analysis instrument at least comprises: infusion pumps, automatic sampling systems, chromatographic columns, chromatographic detection systems, analytical systems, and the like.
The infusion pump is used for providing a mobile phase for the whole chromatographic analysis instrument, wherein the mobile phase is a substance which carries a detected sample to move forwards in the chromatographic analysis instrument, such as acetonitrile-water solution, methanol-water solution and the like.
The automatic sampling system is used for automatically taking out the detected sample from the sample container, mixing the sample with the mobile phase through the proportional valve and then feeding the sample into the chromatographic column.
The chromatographic column is used for separating liquid after the sample and the mobile phase are mixed, and as each component in the sample and the stationary phase (the stationary phase is a phase which is fixed in a chromatographic analysis instrument and separates the sample, such as silica gel and the like) in the chromatographic column have different polarities, when the mobile phase flows through the chromatographic column, the sample is separated out of the mobile phase in sequence through the separation of the stationary phase, and the detection of a detection system is waited.
The chromatographic detection system is used for detecting the separated sample in the chromatographic column, converting the sample into a corresponding optical signal or an electrical signal, and then sending the optical signal or the electrical signal to the analysis system for qualitative and/or quantitative analysis, wherein the chromatographic detection system can be a fluorescence detection system, a diode array detection system, an electrochemical detection system and the like.
The analysis system is upper computer software and is used for storing and analyzing the optical signals or the electrical signals detected by the chromatographic detection system and displaying analysis results to a user.
The automatic sampling system needs to automatically sample from the sample bottle, the sample bottle is placed in the sample tray, the automatic sampling system generally needs to press the corresponding sample bottle through the bottle pressing component, then the sampling needle pierces the rubber gasket of the sample bottle, the sampling needle is contacted with the sample, then sampling is carried out, and the sampling needle needs to be separated from the rubber gasket of the sample bottle after sampling is completed, and returns to the original position to wait for the next sampling.
Throughout the sampling process, the following problems need to be faced:
1. the sample bottles are various in size, and the problem of how to press the sample bottles correctly without excessive force is always present;
2. how to quickly disengage the sampling needle from the sample bottle without lifting the sample bottle is also one of the problems to be solved.
Disclosure of Invention
In order to solve the technical problems, the invention provides an automatic sampling assembly which can quickly and reasonably press a sample bottle to realize sampling, and a sampling needle can be quickly separated from the sample bottle.
The automatic sampling assembly provided by the invention is arranged on a sampling assembly fixing part of an automatic sampling system:
the automatic sampling assembly includes: a tension spring fixing plate, two tension springs, a guide rail, a sliding block, a connecting block, a bottle pressing block and a sampling needle seat,
the connecting block is fixedly connected with the sampling assembly fixing part, and the sliding block and the sampling needle seat are respectively fixed on the connecting block;
the guide rail is arranged on the sliding block in a penetrating way, so that the guide rail and the sliding block form a sliding structure;
the tension spring fixing plate is fixed at the upper end of the guide rail, and the bottle pressing block is fixed at the lower end of the guide rail;
the two tension springs are respectively arranged on two sides of the guide rail, are arranged between the tension spring fixing plate and the connecting block, and are in a stretched state under the action of the tension spring fixing plate and the connecting block;
and a sampling needle is fixed on the sampling needle seat.
According to the automatic sampling assembly, the connecting block is fixedly connected with the fixing part of the sampling assembly to serve as a main body, the sampling needle seat and the sliding block are arranged on the connecting block, the guide rail penetrates through the sliding block to form a sliding structure, the guide rail can slide up and down along the sliding block, the tension spring fixing plate is fixed at the upper end of the guide rail, the tension spring is arranged between the tension spring fixing plate and the sliding block, the tension spring is always in a stretched state, and the bottle pressing block is arranged at the lower end of the guide rail. When the sampling assembly is particularly in operation, the fixing part of the sampling assembly drives the connecting block to move downwards, and the guide rail moves downwards along with the connecting block because the stress of the guide rail is only the tension of the tension spring; after the bottle pressing block at the lower end of the guide rail presses the sampling bottle, the fixing part of the sampling assembly continuously drives the connecting block to move downwards, at the moment, the lower end of the guide rail is propped by the sampling bottle, so that the guide rail does not move relative to the sampling bottle, the connecting block and the sliding block continuously move downwards relative to the guide rail, in the process, the tension spring is gradually stretched by the tension spring fixing plate which is fixed and the connecting block which moves downwards, so that the stress of the tension spring is gradually increased, and the sampling needle arranged on the sampling needle seat can puncture the rubber gasket of the sampling bottle to sample; after the sampling is completed, the sampling assembly fixing part moves upwards in turn to drive the sampling needle to separate from the sampling bottle, and then in the process of further upward movement of the full-use assembly fixing part, the guide rail and the bottle pressing block are driven to move upwards together under the action of the tension force of the tension spring, so that the sampling process is completed once. In the whole sampling process, due to the existence of the guide rail, the guide rail can freely slide relatively along the sliding block under the action of force, the guide rail and the tension spring can realize rapid bottle pressing in a self-adaptive manner no matter the height of the sample bottle, and the sampling needle can not bring up the sample bottle due to the functions of the guide rail and the tension spring in the sampling process, and the whole sampling process is a process of gradually stressing and gradually releasing the sample bottle instead of a process of hard stressing, so that the whole sampling process stressing is very smooth.
As an illustration, in the automatic sampling assembly of the present invention, two pull springs are respectively fixed on the connection block, and the two pull springs are installed between the pull spring fixing plate and the pull spring piece such that axes of the two pull springs are parallel to the guide rail.
As yet another illustration, in the automatic sampling assembly of the present invention, the slider is mounted within a space enclosed by the sampling hub and the connection block.
As still another example, in the automatic sampling assembly of the present invention, the bottle pressing block is provided with a through hole, and the sampling needle fixed to the sampling needle holder is disposed through the through hole.
As another illustration, in the automatic sampling assembly of the present invention, the bottle pressing block includes a connecting layer and a supporting layer, the cross section of the connecting layer is in a U-shaped structure, and the upper part of the U-shaped structure is provided with a square groove matched with the guide rail; the supporting layer is arranged at the bottom of the connecting layer and is cylindrical; the through hole passes through the lower portion of the connection layer and the support layer.
As another example, in the automatic sampling assembly of the present invention, an optocoupler detector is disposed on the connection block, and an optocoupler baffle is correspondingly fixed on the guide rail, where the optocoupler detector and the optocoupler baffle are used for detecting that the automatic sampling assembly is in an initial zero position.
As another example, in the automatic sampling assembly of the present invention, the optocoupler baffle has an L shape, wherein one side is fixed to the guide rail, and the other side corresponds to the detection position of the optocoupler detector.
As another example, in the automatic sampling assembly of the present invention, the pull spring plate is provided with a plurality of tension spring fixing holes in an aligned manner.
In order to solve the above-mentioned problems in the background art, the present invention further provides a three-dimensional automatic sampling system, which includes an automatic sampling assembly mounted on a sampling assembly fixing portion of the automatic sampling system:
the automatic sampling assembly includes: a tension spring fixing plate, two tension springs, a guide rail, a sliding block, a connecting block, a bottle pressing block and a sampling needle seat,
the connecting block is fixedly connected with the sampling assembly fixing part, and the sliding block and the sampling needle seat are respectively fixed on the connecting block;
the guide rail is arranged on the sliding block in a penetrating way, so that the guide rail and the sliding block form a sliding structure;
the tension spring fixing plate is fixed at the upper end of the guide rail, and the bottle pressing block is fixed at the lower end of the guide rail;
the two tension springs are respectively arranged on two sides of the guide rail, are arranged between the tension spring fixing plate and the connecting block, and are in a stretched state under the action of the tension spring fixing plate and the connecting block;
and a sampling needle is fixed on the sampling needle seat.
According to the automatic sampling assembly, the guide rail sliding block structure and the tension spring structure are arranged to serve as force buffering structures in the sampling process, the guide rail and the tension spring can realize rapid bottle pressing in a self-adaptive mode no matter the height of a sample bottle, the sample bottle cannot be carried by a sampling needle due to the effects of the guide rail and the tension spring in the sampling process, the whole sampling process is a process of gradually stressing and gradually releasing force for the sample bottle, and not a process of hard stressing, and therefore the whole sampling process stressing is very smooth.
Drawings
FIG. 1 is a schematic diagram of a three-dimensional automatic sampling system 100 of the present invention;
FIG. 2 is a schematic diagram of the structure of a front view of the three-dimensional automatic sampling system 100 of the present invention;
FIG. 3 is a schematic top view of the three-dimensional automatic sampling system 100 of the present invention;
fig. 4 is a schematic structural view of the X-direction moving member 1 of the present invention;
fig. 5 is a schematic view of the structure of the Y-direction moving member 2 of the present invention;
fig. 6 is a schematic view of still another structure of the Y-direction moving member 2 of the present invention;
fig. 7 is a schematic view of the structure of the Z-direction moving member 3 of the present invention;
fig. 8 is a schematic view of still another structure of the Z-direction moving member 3 of the present invention;
fig. 9 is a schematic view of the structure of the bottle pressing block 511 of the present invention;
wherein 100 is a three-dimensional automatic sampling system, 1 and 1' are X-direction moving members, 2 and 2' are Y-direction moving members, 3 and 3' are Z-direction moving members, 4 is a base plate, 5 is a sampling section, 6 is a sampling valve, 11 and 12 are mounting plates, 13 and 15 are optical axes, 14 is a first lead screw, 16 is a square shaft, 17 is a first lead screw driving section, 18 is a moving block, 21 is a second lead screw, 22 is a second lead screw driving section, 23 is a lead screw nut, 24 is an adapter plate, 25 and 26 are slide rails, 27 is a moving cover plate, 28 is a sample holder, 29 is a sample bottle, 210 is a first slider, 211 is a second slider, 31 is a gear, 32 is a square shaft driving section, 33 is a rack, 51 is a first guide rail, 52 is a third slider, 53 is a fourth slider, 54 is a connecting block, 55 is a second guide rail, 56 is a fifth slider, 57 is a sampling needle holder, 58 is a tension spring fixing plate, 59 and 510 are tension springs, 511 is a bottle pressing block, 512 is a sampling needle, 513 and 514 is a tension spring, 515 is a detector, 515 is a shutter, 61 is a detector is a shutter, 61 is a coupling layer, and a coupling layer is a through hole.
Detailed Description
In order that the above-recited objects, features and advantages of the present invention will become more readily apparent, a more particular description of the invention will be rendered by reference to the appended drawings and appended detailed description.
Referring to fig. 1 in combination, fig. 1 shows a three-dimensional automatic sampling system 100 of the present invention, which includes an X-direction moving system including two sets of X-direction moving members 1 and 1' arranged in parallel, a Y-direction moving system including two sets of Y-direction moving members 2 and 2' arranged in parallel, a Z-direction moving system including two sets of Z-direction moving members 3 and 3' mounted on the two sets of X-direction moving members 1 and 1', respectively, wherein the X-direction moving members 1 and 1' are mounted on the base plate 4, and the Y-direction moving members 2 and 2' are mounted on the base plate 4 between the X-direction moving members 1 and 1 '.
The X-direction moving system will be described in detail with reference to fig. 2 and 4, in which the X-direction moving member 1 is a specific embodiment.
In the present embodiment, the X-direction moving member 1 includes mounting plates 11 and 12, optical axes 13 and 15, a first screw 14, a moving block 18, and a first screw driving portion 17, which are vertically disposed on both sides.
The mounting plates 11 and 12 are vertically mounted on the base plate 4, and the mounting plates 11 and 12 and the base plate 4 together form a support structure for the three-dimensional automatic sampling system 1.
The optical axes 13 and 15 and the screw 14 are installed between the two installation plates 11 and 12 along the X direction, which is the horizontal direction in this embodiment, wherein the screw 14 is installed in the middle of the optical axis 13 and the optical axis 15, so that the screw 14, the optical axis 13 and the optical axis 15 are in a straight line in the Z direction.
One end of the screw 14 is connected with a screw driving part 17, in this embodiment, the screw driving part 17 is mounted on the outer side of the mounting plate 11, and the screw driving part 17 can drive the screw 14 to rotate. The screw driving unit 17 may be constituted by a stepping motor directly, the stepping motor may be directly connected to the screw 14, or the stepping motor may be realized by a timing belt, and the stepping motor may drive the screw 14 to rotate by the timing belt.
The motion block 18 is arranged through the screw rod 14 and the optical axes 13 and 15, the motion block 18 and the screw rod 14 form a transmission structure, the screw rod driving part 17 can drive the screw rod 14 to rotate, the rotation of the screw rod 14 can drive the motion block 18 to move left and right along the X direction, namely, the rotation motion of the motor is converted into the linear motion of the motion block 18, and the motion direction, the motion speed, the motion position and the like of the motion block 18 are controlled by the rotation parameters of the motor.
The moving block 18 is generally connected with the screw rod 14 through a screw rod nut, the screw rod 14 is provided with the screw rod nut matched with the screw rod nut, and then the moving block 18 is fixed with the screw rod nut, so that the transmission connection between the screw rod 14 and the moving block 18 can be realized.
Since the moving block 18 is further disposed through the two optical axes 13 and 15, the moving block 18 is limited by the optical axes 13 and 15 and the screw rod 14 when moving along the X direction, so that the moving block 18 cannot swing or shake back and forth, the left and right movement of the moving block 18 on a straight line along the X direction is ensured, and the accuracy of the automatic sampling system 100 is improved.
As a modification, the screw driving portion 17 may be provided outside the mounting plate 12.
As a modification, the X-direction moving member 1 may include only one of the optical axes 13 and 15.
As a variant, the position of the screw 14 may not be between the optical axis 13 and the optical axis 15, for example the screw 14 is arranged above the optical axis 13 and the optical axis 15.
As yet another modification, the lead screw 14, the optical axes 13 and 15 may be staggered in the Z direction.
The present embodiment describes the Y-direction moving system in detail with reference to fig. 1, 2, 3, 5, and 6, taking the Y-direction moving member 2 as a specific embodiment.
The Y-direction moving members 2 and 2 'are mounted on the base plate 4 between the two mounting plates 11 and 12 and are mounted in parallel in the Y-direction, and the structures of the two Y-direction moving members 2 and 2' are identical.
The Y-direction moving part 2 comprises a fixing frame, a second screw rod 21, a second screw rod driving part 22 and a sample tray, wherein the screw rod 21 is arranged on the fixing frame along the Y direction, the screw rod driving part 22 is fixed on the fixing frame, an output rotating shaft of the screw rod driving part 22 is fixedly connected with the screw rod 21, the screw rod driving part 22 can drive the screw rod 21 to rotate, the screw rod 21 and the sample tray form a transmission structure, and the rotation of the screw rod 21 can drive the sample tray to linearly move along the Y direction.
In this embodiment, the Y-direction moving part 2 further includes two slide rails 25 and 26, and the sample tray includes an adapter plate 24, a movable cover plate 27, and a sample holder 28.
The slide rails 25 and 26 are parallel to the screw 21 and are respectively arranged at two sides of the screw 21 and fixed on the fixed frame, a screw nut 23 is arranged at the bottom of the sample tray, the screw nut 23 and the screw 21 directly form a transmission structure, and a first sliding block 210 and a second sliding block 211 matched with the slide rails 25 and 26 are respectively arranged on the two slide rails. The screw driving part 22 can drive the screw 21 to rotate, and the rotation of the screw 21 drives the screw nut 23 to linearly move forwards or backwards in the Y direction, and the screw nut 23 is fixed with the sample tray, so that the sample tray is driven by the screw nut 23 to linearly move forwards or backwards in the Y direction.
Since the sample tray is generally configured as a tray capable of preventing a plurality of sample bottles 29, and has a certain length and width, in order to prevent the sample tray from tilting to a certain side, two slide rails 25 and 26 are provided to support the sample tray, so that gravity of the sample tray is uniformly distributed when the sample tray moves under the drive of the screw 21, and sliding along the Y direction is smooth and accurate; the slide rails 25 and 26 can effectively support the sample tray, particularly when the sampling portion applies a downward force to the sample bottle 29.
The adapter plate 24 is the lowest part of the sample tray, the bottom of the adapter plate 24 is fixedly connected with the screw nut 23, the sliding blocks 25 and 26 respectively, the upper part of the adapter plate 24 is provided with the movable cover plate 27, the upper part of the movable cover plate 27 is provided with the sample rack 28, and the sample rack 28 is used for placing the sample bottles 29. This arrangement makes the Y-direction moving member 2 easy to assemble and easy to replace the sample tray.
As an example, the slide rails 210 and 211 in the present embodiment are cylindrical slide rails, and the inner sides of the corresponding slide blocks 210 and 211 are cylindrical structures.
As a modification, the slide rails 25 and 26 may also be square slide rails or other shaped slide rails.
As yet another modification, the sliders corresponding to the slide rails 25 and 26 in the present embodiment may be provided in plural.
As a further variation, the slide rails 25 and 26 in the present embodiment may also be omitted, using only the lead screw 21 itself as the support structure for the sample tray.
As yet another modification, the sample tray in this embodiment may also be an integrally formed structure, instead of being separately designed as the adapter plate 24, the movable cover plate 27, and the sample holder 28.
The screw driving unit 22 may be constituted by a stepping motor directly, the stepping motor directly connected to the screw 21, or the stepping motor may be realized by a timing belt, and the stepping motor may drive the screw 21 to rotate by the timing belt.
The sample bottle 29 may be any of various conventional sample bottles for holding a liquid sample.
By way of illustration, the Y-direction moving members 2 and 2' may be provided to be completely identical, and screw driving portions of both may be provided on both sides in the Y-direction, respectively.
The Y-direction moving system will be described in detail with reference to fig. 1, 2, 4, 7, and 8, in which the Z-direction moving member 3 is a specific embodiment.
The Z-direction moving part 3 and the Z-direction moving part 3' are completely consistent structures, are respectively arranged on the two X-direction moving parts 1 and 1', and move leftwards and rightwards along the X direction under the drive of the X-direction moving parts 1 and 1 '.
The Z-direction moving member 3 includes a square shaft 16, a gear 31, a square shaft driving unit 32, a rack 33, and a sampling unit 5.
The square shaft 16 is disposed between the two mounting plates 11 and 12, parallel to the screw rod 14 and the optical axis 13 and the optical axis 15, the gear 31 is disposed on the moving block 18 and sleeved on the square shaft 16, the square shaft driving part 32 is fixedly connected with the square shaft 16, the gear 31 is matched with the rack 33 along the Z direction, the sampling part 5 is fixedly mounted with the rack 33, and can drive the sampling part 5 to move left and right along the X direction and move up and down along the Z direction, and the square shaft driving part 32 is disposed outside the mounting plate 12 or outside the mounting plate 11.
Since the gear 31 is fixedly connected with the moving block 18, the gear can move leftwards or rightwards along the X direction under the driving of the moving block 18, and the sampling part 5 can be driven to move leftwards or rightwards along the X direction. The square shaft driving part 32 can drive the square shaft 16 to rotate, the rotation of the square shaft 16 can drive the gear 31 to rotate, and the rotation of the gear 31 can further drive the rack 33 to move upwards or downwards along the Z direction, so as to drive the sampling part 5 to move upwards or downwards along the Z direction for sampling.
The sampling unit 5 will be described in detail below.
The sampling part 5 comprises a first guide rail 51, a third guide rail 52, a fourth guide rail 53, a connecting block 54, a second guide rail 55, a fifth guide rail 56, a sampling needle seat 57, a tension spring fixing plate 58, tension springs 59 and 510, a bottle pressing block 511, a sampling needle 512, tension spring sheets 513 and 514, an optocoupler detector 515 and an optocoupler baffle 516, wherein the connecting block 54, the second guide rail 55, the fifth guide rail 56, the sampling needle seat 57, the tension spring fixing plate 58, tension springs 59 and 510, the bottle pressing block 511, the sampling needle 512, tension spring sheets 513 and 514, the optocoupler detector 515, the optocoupler baffle 516 and the like form an (automatic) sampling assembly, and the gear 31, the rack 33, the moving block 18, the first guide rail 51 and the like form a sampling assembly fixing part of the (automatic) sampling assembly.
The first guide rail 51 and the rack 33 are fixed together along the Z direction, so that the first guide rail 51 can move up and down along the Z direction under the driving of the rack 33.
The sliding blocks 52 and 53 are fixedly installed on the moving block 18, and the sliding blocks 52 and 53 and the guide rail 51 form a sliding fit structure, so that the guide rail 51 slides along a path formed by the sliding blocks 52 and 53 when moving up and down in the Z direction, and left and right offset cannot be generated.
The connecting block 54 is fixedly connected with the guide rail 51, and the connecting block 54 can move up and down along the Z direction under the drive of the guide rail 51.
The fifth slider 56 and the sampling needle seat 57 are both installed on the connecting block 54, and the slider 56 is installed in the space formed by surrounding the sampling needle seat 57 and the connecting block 54, so that the space is saved, and the installation of the slider 56 is firmer and is not easy to deviate.
The second guide rail 55 is disposed on the slider 56 in a penetrating manner, so that the guide rail 55 and the slider 56 form a sliding structure, and the guide rail 55 can move up and down along a line defined by the slider 56.
The upper end of the guide rail 55 is fixed with a tension spring fixing plate 58, the tension spring fixing plate 58 is of a T-shaped structure, tension springs 59 and 510 are arranged on two sides of the guide rail 55 respectively, the tension springs 59 and 510 are arranged between the tension spring fixing plate 58 and the connecting block 54 respectively, and the tension springs 59 and 510 are in a stretched state all the time under the action of the tension spring fixing plate 58 and the connecting block 54.
In this embodiment, two tension spring sheets 513 and 514 are respectively fixed on both sides of the connection block 54, and tension springs 59 and 510 are installed between the tension spring sheets 513 and 514 and the tension spring fixing plate 58, and the axes of the tension springs 59 and 510 are parallel to the guide rail 55, that is, the axes of the two tension springs 59 and 510 are aligned along the Z-axis direction, so that the best effect can be achieved.
The axes of the tension springs 59 and 510 refer to: because the tension spring is generally in a cylindrical structure, the axis of the cylinder is a straight line defined by the center of a circle of the circular section of the cylinder, and the straight line is the axis of the tension spring.
A bottle pressing block 511 is installed at the lower end of the guide rail 55, and the bottle pressing block 511 is used for fixing the sample bottle 29 during sampling so that the sample bottle 29 does not shake during sampling.
A sampling needle 512 is mounted on the sampling needle holder 57, and a through hole 517 is provided on the vial holder 511 such that the sampling needle 512 can pass through the through hole 517.
In this embodiment, referring to fig. 9, the bottle pressing block 511 includes a connecting layer 61 and a supporting layer 62, the cross section of the connecting layer 61 is in a U-shaped structure, the upper portion of the U-shaped structure is provided with a square groove 63 matching with the guide rail 55, the lower portion of the U-shaped structure is a through hole 517, the supporting layer 62 is in a cylindrical shape and is disposed at the bottom of the connecting layer 61, the supporting layer 62 directly contacts with the sample bottle 29 during sampling, and the middle portion of the supporting layer 62 is also the through hole 517, that is, the through hole 517 passes through the lower portion of the connecting layer 61 and the supporting layer 62, so that the sampling needle 512 can pass through the through hole 517 and enter the sample bottle 29.
A screw hole may be further provided at the square groove 63 of the bottle pressing block 511 for fixing the bottle pressing block 511 with the guide rail 55 by a screw.
In this embodiment, an optocoupler detector 515 is further disposed on the connection block 54, and an optocoupler baffle 516 is correspondingly disposed on the guide rail 55, where the optocoupler detector 515 and the optocoupler baffle 516 may be used to detect that the sampling portion 5 (or the auto-sampling assembly) is at an initial zero position or a certain predetermined position.
As a variant, the axial direction of the tension springs 59 and 510 may also deviate from the Z-axis direction, for example, the lower parts of the two tension springs 59 and 510 may be retracted in the direction of the guide rail 55.
As a variant, the connection block 54 can be directly connected to the tension springs 59 and 510 without pulling the leaves 513 and 514.
As a modification, the slider 56 may be mounted not in the space surrounded by the connection block 54 and the sampling needle holder 57 but separately.
As a modification, the vial block 511 may be provided with a semi-surrounding hole or the like to fix the sample vial 29, and the sample needle 512 may be inserted into the sample vial 29 through the vial block 511.
As a modification, the bottle pressing block 511 may have a structure having a shape such as a trapezoid or a rectangle, and the effect of fixing the sample bottle 29 can be achieved.
As an example, the optocoupler baffle 516 is L-shaped, one side is fixed to the guide rail 55, the other side corresponds to the detection position of the optocoupler detector 515, the optocoupler baffle 516 may reach the detection position of the optocoupler detector 515 under the driving of the guide rail 55, which indicates that the sampling portion 5 (or the automatic sampling assembly) reaches a predetermined initial zero position, and when sampling, the optocoupler baffle 516 leaves the detection position of the optocoupler detector 515 under the driving of the guide rail 55 to perform sampling.
As an example, the tension spring sheets 513 and 514 are provided with a plurality of tension spring fixing holes in a row, and different tension spring fixing holes may be selected according to the magnitudes of the tension forces of the tension springs 59 and 510.
The specific sampling process is described in detail below with reference to fig. 1-9.
With the orientation shown in fig. 2 as the forward direction, when a user uses the three-dimensional automatic sampling system 100 according to the present invention to sample, the user needs to place sample bottles 29 with samples in the sample holders 28 of the Y-direction moving parts 2 and 2', the sample bottles 29 can be selected according to the needs, a plurality of sample bottles 29 can be placed on the sample holders 28, and the same samples or different samples can be placed in the sample bottles on the two Y-direction moving parts 2 and 2'.
The fixed ends of the two sampling needles 512 of the two Z-direction moving parts 3 and 3' are connected to the same sampling valve 6 through respective conduits, and the sampling valve 6 may be a six-way valve, an eight-way valve, etc., and the sampling valve 6 shown in fig. 1 is a six-way valve.
In particular connection, the sampling needle 512 of the Z-direction moving part 3 is connected to one of the sampling ends of the sampling valve 6 through a conduit, and the sampling needle of the Z-direction moving part 3' is connected to the other sampling end of the sampling valve 6 through a conduit.
When a sample is specifically taken, in the X-direction moving component 1, the first screw driving part 17 drives the screw 14 to rotate, the screw 14 drives the moving block 18 and the whole Z-direction moving component 3 connected with the moving block 18 to move leftwards in the X-direction to the upper part of the Y-direction moving component 2, and the Y-direction moving component 2 is driven by the second screw driving part 22, and the screw 21 rotates to drive the sample rack 28 to move forwards in the Y-direction to the lower part of the X-direction moving component 1, so that the sampling needle 512 of the Z-direction moving component 3 is aligned with the sample bottle 29 on the Y-direction moving component 2; in the X-direction moving part 1', the first screw driving part drives the screw to rotate, the screw drives the moving block and the whole Z-direction moving part connected with the moving block to move rightwards to the upper part of the Y-direction moving part 2' along the X direction, and in the Y-direction moving part 2', the screw is driven by the second screw driving part to rotate to drive the sample rack 28 to move backwards to the lower part of the X-direction moving part 1' along the Y direction, so that the sampling needle of the Z-direction moving part 3 'is aligned with the sample bottle on the Y-direction moving part 2'.
The sampling valve 6 is switched to a passage connected with a sampling needle 512 of the Z-direction moving component 3, then a square shaft driving part 32 of the Z-direction moving component 3 moves to drive a square shaft 16 and a gear 31 to rotate, the gear 31 rotates to drive a rack 33 to move downwards, the rack 33 drives a guide rail 51 fixedly connected with the rack 33 to move downwards synchronously, the guide rail 51 drives a connecting block 54 to move downwards, the whole sampling part 5 connected with the connecting block 54 moves downwards, a bottle pressing block 511 firstly contacts and presses a sample bottle 29 in the downward movement process, the whole sampling part 5 continues to move downwards under the driving of the square shaft driving part 32, at the moment, since the bottle pressing block 511 is fixedly contacted with the sample bottle 29, the bottle pressing block 511 and the guide rail 55 do not move any more, and the rack 33, the guide rail 51, the connecting block 54, the sampling needle 512 and the like continue to move downwards, the downward movement of the connecting block 54 and the static state of the guide rail 55 continuously stretch the two tension springs 59 and 510, the tension springs 59 and 510 continuously act under tension to further stretch until the sampling needle 512 pierces the rubber bottle cap of the sample bottle 29 and enters the sample bottle 29 to sample, the sample obtained by the sampling needle 512 entering the sample bottle 29 enters the dosing ring of the sample valve 6 to finish sampling, then the square shaft driving part 32 reversely rotates to drive the square shaft 16 to reversely rotate, the square shaft 16 reversely rotates the gear 31, the reverse rotation of the gear 31 drives the rack 33 and the guide rail 51 to move upwards, the guide rail 51 drives the connecting block 54 to upwards move, and the like, the bottle pressing block 511 keeps still due to the fact that the tension of the tension springs 59 and 510 continuously exert downward force on the guide rail 55, the sampling needle 512 gradually releases the rubber bottle cap of the sample bottle 29, then the tension of the tension springs 59 and 510 gradually shrink in the process of the continuous upward movement of the connecting block 54, the freedom of the guide rail 55 is gradually released, the bottle pressing block 511 is driven to leave the sample bottle and is restored to the initial position, and the sampling process of the first step is completed.
When the sampling in the first step is completed, the first screw driving part 17 drives the whole sampling part 5 to move leftwards to the needle washing position, and the needle washing operation (including the inner wall and the outer wall of the sampling needle 512) is performed.
In the process of the above-mentioned needle washing operation, the sampling valve 6 is switched to the sampling needle connecting passage of the Z-direction moving part 3', and the Z-direction moving part 3' repeats the sampling process of the above-mentioned Z-direction moving part 3: the square shaft driving part of the Z-direction moving part 3' moves to drive the square shaft and the gear to rotate, the gear rotates to drive the rack to move downwards, the rack drives the guide rail fixedly connected with the rack to move downwards synchronously, the guide rail drives the connecting block to move downwards, the whole sampling part connected with the connecting block moves downwards, the bottle pressing block firstly contacts and presses the sample bottle in the downward movement process, the whole sampling part continues to move downwards under the driving of the square shaft driving part, at the moment, the bottle pressing block and the guide rail do not move any more due to the fact that the bottle pressing block is fixedly contacted with the sample bottle, the rack, the guide rail, the connecting block, the sampling needle and the like continue to move downwards, the downward movement of the connecting block and the static of the guide rail continuously stretch two tension springs and the tension spring and continuously until the sampling needle pierces the rubber bottle cap of the sample bottle to sample bottle, the sample bottle is entered, the sample bottle is sampled in the sample bottle is completed, the sample bottle is reversely rotated by the square shaft driving part, the square shaft can drive the square shaft to reversely rotate, the square shaft can drive the gear to reversely rotate, the gear rotates, the gear is continuously in the upward tension is continuously released, the initial tension is continuously applied to the sample bottle cap is gradually released, the upward tension is continuously due to the fact that the upward tension is continuously applied to the upward tension of the sample bottle is continuously, and the sample bottle is continuously pulled in the upward, and the sample bottle is continuously in the sample is sampled.
After the sampling in the second step is completed, the first screw driving part drives the whole sampling part to move leftwards (or rightwards) to the needle washing position, the needle washing operation (including the inner wall, the outer wall and the like of the sampling needle) is performed, the X-direction moving part 1 and the Z-direction moving part 3 continue the sampling operation in the next step, and the processes are repeated sequentially.
In the above sampling process, the two Y-direction moving members 2 and 2' may be interchanged, or the sampling process may be completed by using only one Y-direction moving member, and only the Y-direction moving member may be required to move back and forth each time sampling is performed.
It should be further noted that, since the three-dimensional automatic sampling system 100 of the present invention includes two groups of sampling systems that can freely form a sampling system, sampling operations of two samples can be performed simultaneously, for example, the X-direction moving component 1, the Y-direction moving component 2, and the Z-direction moving component 3 are used for sampling the sample 1 therein, and the X-direction moving component 1', the Y-direction moving component 2', and the Z-direction moving component 3' are used for sampling the sample 2 therein, so that sampling schemes are more diversified.
As can be seen from the above description of the sampling process, the sampling part 5 (or the automatic sampling assembly) of the present invention adopts the fixing manner of the free guide rail 55 and the tension springs 59 and 510 as the bottle pressing block 511, so that the sample bottles 29 with different heights can be perfectly adapted, the bottle pressing block 511 can not be pressed by the excessive force, the force generated by the tension springs 59 and 510 in the process that the sampling needle 512 is separated from the sample bottles 29 can be pressed again, the whole sampling process can be fast, accurate and efficient, and the problem of how to accurately press the sample bottles without excessive force caused by various sample bottle sizes and how to quickly separate the sampling needle from the sample bottles without bringing up the sample bottles can be solved by the scheme of the sampling part 5 (or the automatic sampling assembly) of the present invention.
The sampling process of the three-dimensional automatic sampling system 100 of the present invention is sequentially switched between two three-dimensional automatic sampling systems (consisting of an X-direction moving part 1, a Y-direction moving part 2, a Z-direction moving part 3, and an X-direction moving part 1', a Y-direction moving part 2', and a Z-direction moving part 3', respectively), even if one of the three-dimensional sampling systems is operated in a needle washing process, the other three-dimensional sampling system can continuously operate, the sampling efficiency of the automatic sampling system is greatly improved, the time interval between two samplings is reduced, the analysis efficiency of a chromatographic analysis instrument using the three-dimensional automatic sampling system 100 can be improved, and the analysis time is shortened, so the three-dimensional automatic sampling system of the present invention solves the problem of low sampling efficiency of the automatic sampling system.
The foregoing description of the embodiments is merely exemplary of the present invention and is not intended to limit the scope of the invention, but is to be construed as including any modifications, equivalents, and alternatives falling within the spirit and principles of the invention.
Claims (9)
1. An automatic sampling assembly for mounting on a sampling assembly fixture of an automatic sampling system, comprising:
the automatic sampling assembly includes: a tension spring fixing plate, two tension springs, a guide rail, a sliding block, a connecting block, a bottle pressing block and a sampling needle seat,
the connecting block is fixedly connected with the sampling assembly fixing part, and the sliding block and the sampling needle seat are respectively fixed on the connecting block;
the guide rail is arranged on the sliding block in a penetrating way, so that the guide rail and the sliding block form a sliding structure;
the tension spring fixing plate is fixed at the upper end of the guide rail, and the bottle pressing block is fixed at the lower end of the guide rail;
the two tension springs are respectively arranged on two sides of the guide rail, are arranged between the tension spring fixing plate and the connecting block, and are in a stretched state under the action of the tension spring fixing plate and the connecting block;
a sampling needle is fixed on the sampling needle seat, wherein,
the sampling assembly fixing part drives the connecting block to move downwards, and the guide rail moves downwards along with the connecting block; after the bottle pressing block at the lower end of the guide rail presses the sampling bottle, the fixing part of the sampling assembly continuously drives the connecting block to move downwards, at the moment, the lower end of the guide rail is propped by the sampling bottle, so that the guide rail does not move relative to the sampling bottle, the connecting block and the sliding block continuously move downwards relative to the guide rail, in the process, the tension spring is gradually stretched by the tension spring fixing plate which is fixed and the connecting block which moves downwards, so that the stress of the tension spring is gradually increased, and the sampling needle arranged on the sampling needle seat can puncture the rubber gasket of the sampling bottle to sample; after the sampling is completed, the sampling assembly fixing part moves upwards in turn to drive the sampling needle to separate from the sampling bottle, and then in the process of further upward movement of the sampling assembly fixing part, the guide rail and the bottle pressing block are driven to move upwards together under the action of the tension force of the tension spring, so that the primary sampling process is completed.
2. The automatic sampling assembly of claim 1, wherein:
two pull springs are respectively fixed on the connecting block, the two tension springs are arranged between the tension spring fixing plate and the tension spring sheet, and the axes of the two tension springs are parallel to the guide rail.
3. An automatic sampling assembly according to claim 1 or 2, wherein:
the sliding block is arranged in a space surrounded by the sampling needle seat and the connecting block.
4. The automatic sampling assembly of claim 1, wherein:
the bottle pressing block is provided with a through hole, and the sampling needle fixed on the sampling needle seat passes through the through hole.
5. The automatic sampling assembly of claim 4, wherein:
the bottle pressing block comprises a connecting layer and a supporting layer,
the cross section of the connecting layer is of a U-shaped structure, and the upper part of the U-shaped structure is provided with a square groove matched with the guide rail;
the supporting layer is arranged at the bottom of the connecting layer and is cylindrical;
the through hole passes through the lower portion of the connection layer and the support layer.
6. The automatic sampling assembly of claim 1, wherein:
the automatic sampling device comprises a guide rail, and is characterized in that an optical coupler detector is arranged on the connecting block, an optical coupler baffle is correspondingly fixed on the guide rail, and the optical coupler detector and the optical coupler baffle are used for detecting that the automatic sampling assembly is in an initial zero position.
7. The automatic sampling assembly of claim 6, wherein:
the optocoupler baffle is L-shaped, one edge of the optocoupler baffle is fixed with the guide rail, and the other edge of the optocoupler baffle corresponds to the detection position of the optocoupler detector.
8. The automatic sampling assembly of claim 2, wherein:
a plurality of tension spring fixing holes are arranged on the tension spring pieces in a arrayed mode.
9. A three-dimensional automatic sampling system, characterized by: an automatic sampling assembly as claimed in any one of claims 1 to 8.
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| CN108225874B (en) * | 2017-12-18 | 2024-07-19 | 中国原子能科学研究院 | Mechanical arm separation module |
| CN107991505A (en) * | 2017-12-21 | 2018-05-04 | 睿科仪器（厦门）有限公司 | A kind of auto spring puncture needle sampling structure |
| CN108646009A (en) * | 2018-03-26 | 2018-10-12 | 潍坊科技学院 | A kind of multifunctional examining experiment device when blood sampling and its method of inspection |
| CN109633051A (en) * | 2019-02-19 | 2019-04-16 | 安徽皖仪科技股份有限公司 | Autosampler, liquid chromatograph and liquid chromatograph automatic sampling method |
| CN111896760B (en) * | 2020-07-15 | 2024-08-13 | 宁波华仪宁创智能科技有限公司 | Control method and automatic sample injection method for closed space |
| CN118191221A (en) * | 2024-05-20 | 2024-06-14 | 中国科学院烟台海岸带研究所 | Seawater chemical oxygen demand detection system and detection method |
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