CN107397984B

CN107397984B - Anhydrous dry type blood plasma heating and thawing instrument

Info

Publication number: CN107397984B
Application number: CN201710658910.2A
Authority: CN
Inventors: 肖阳; 钱建民; 孙芸
Original assignee: JIANGSU HAIZE MEDICAL SCIENTIFIC DEVELOPMENT CO LTD
Current assignee: JIANGSU HAIZE MEDICAL SCIENTIFIC DEVELOPMENT CO LTD
Priority date: 2017-08-04
Filing date: 2017-08-04
Publication date: 2020-07-14
Anticipated expiration: 2037-08-04
Also published as: CN107397984A

Abstract

A dry-type plasma heating unfreezing instrument without water is characterized by comprising an upper cover (1), a lower box body (2), a unfreezing groove (4), a swinging mechanism (5) and a buffer mechanism (6), wherein the upper cover (1) and the lower box body (2) are connected through a parallel connecting rod (10), the swinging mechanism (5) is divided into an upper moving part and a lower moving part which are respectively arranged inside the upper cover (1) and the lower box body (2), and the upper moving part and the lower moving part are connected through a connecting sheet (11) to realize synchronous movement; the upper half and the lower half of the unfreezing groove (4) are respectively arranged on the corresponding upper swing plate and the lower swing plate (8) and are driven by the swing mechanism (5) to do reciprocating motion; the lower moving part of the swing mechanism (5) is arranged on a support plate (9), the support plate (9) is supported on a buffer mechanism (6), and the buffer mechanism (6) is arranged in the lower box body (2); various electrical equipment is arranged below the supporting plate (9). The invention has simple structure, rapid and stable heating and good unfreezing effect.

Description

Anhydrous dry type blood plasma heating and thawing instrument

Technical Field

The invention relates to a medical instrument, in particular to a blood thawing device which can be used in an operation and can replace the traditional water bath heating for thawing blood plasma, so that the frozen blood plasma is thawed and heated to 37 ℃ for a patient to use. In particular to a waterless dry type plasma heating and thawing instrument which can be used in an operating room.

Background

Researches show that the temperature of unfrozen and warmed blood reaches 32-35 ℃, the application of the unfrozen and warmed blood in clinical rescue and treatment of post-traumatic hypovolemic shock can reduce the incidence rate of shivering, hypothermia and the like of a post-traumatic hypovolemic shock patient after the patient is transfused into low-temperature reservoir blood, and the microcirculation improvement is facilitated.

Plasma thawing is always a concern of all hospitals, and plasma is a special precious resource and needs to be carefully searched and researched for all reasons and countermeasures causing plasma rejection. At present, most of blood plasma is melted in a water bath at 37 ℃, and higher temperature can accelerate the melting of the blood plasma, but can accelerate the loss of coagulation factors in the blood plasma and the denaturation of blood plasma proteins. A too low temperature reduces the loss of coagulation factors, but a longer thawing time also increases the loss of coagulation factors.

At present, the full-automatic plasma thawing machine is widely used clinically, and a circulating water bath method is generally adopted, and the method has the advantages of large plasma thawing amount at one time, short time and good effect. However, the method easily causes the label on the surface of the plasma bag to easily fall off or be fuzzy, seriously influences the identification and distribution of the plasma, is easy to generate bacterial pollution and is strict in use and maintenance. The dry heating for thawing the plasma is the most favored plasma thawing mode at present, which makes up the shortage of plasma thawing in a circulating water bath, but the thawing time is slightly longer, but is completely within the acceptable range, and the price is expensive. The microwave oven thawing box can rapidly thaw plasma within 3-5 minutes, but the method has more requirements, the technology is not mature enough, the quantity of plasma thawed at one time is less, and the equipment is expensive. It has now been found that thawing frozen canine plasma using microwave heating results in a significant reduction in the concentration of factor II, factor IX, factor X, factor XI, fibrinogen, von Willebrand factor, antithrombin, protein C and albumin, and a significant increase in the prothrombin time and the activated partial thromboplastin time. It can be seen that this method of thawing FFP (fresh-fresh plasma) may result in greater loss of clotting factors.

Due to the particularity of plasma, the temperature requirement for heating and thawing the plasma is high. In order to facilitate temperature control, water is generally used as a heat conducting medium in the devices on the market at present, and evaporation of the water can pollute the environment of an operating room, so that the devices are not suitable for being used in the operating room, and the distribution of the plasma bags is complicated. Most of the devices have large one-time unfreezing amount, the single-tank temperature control is not easy to realize, and the devices can only be used for heating and unfreezing the blood plasma generally and have single function. Therefore, a new type of blood plasma heating and thawing instrument is needed to be invented.

Disclosure of Invention

The invention aims to design an anhydrous dry type plasma heating thawing instrument which is electrically heated, can be used in an operating room, has adjustable thawing temperature and good thawing process uniformity and consistency, and aims to solve the problems that the existing water bath blood thawing equipment has low thawing speed, is not suitable for being used in the operating room, and an electric heating thawing device has a complex structure, high cost and poor effect and is easy to cause the quality damage of blood products.

The technical scheme of the invention is as follows:

a kind of anhydrous dry-type plasma heats the unfreezing appearance, its characteristic is that it includes 1 upper cover, lower container body 2, unfreezing trough 4, swing mechanism 5 and buffer gear 6, link to each other through the parallel tie rod 10 between lower container body 2 and the upper cover 1, when the parallel tie rod 10 props up, the upper cover 1 separates from lower container body 2 and drives and installs in upper cover and lower container body, upper half and lower half unfreezing trough 4 that set up symmetrically separately, in order to place needing to unfreeze the plasma product 7, install the electric heating plate 12 in upper half and lower half unfreeze trough 4; when the parallel connecting rod 10 is folded into a horizontal state, the upper cover 2 and the lower box body 2 are buckled into a whole; the swing mechanism 5 is divided into an upper moving part and a lower moving part which are respectively arranged in the upper cover 1 and the lower box body 2, and the upper moving part and the lower moving part are connected through a connecting sheet 11 to realize synchronous movement; the upper half and the lower half of the unfreezing groove 4 are respectively arranged on the corresponding upper and lower swing plates 8 and are driven by the swing mechanism 5 to do reciprocating motion; the lower moving part of the swing mechanism 5 is arranged on a support plate 9, the support plate 9 is supported on a buffer mechanism 6, and the buffer mechanism 6 is arranged in the lower box body 2; various electrical devices are mounted below the support plate 9.

The thawing tank 4 comprises a heating plate 12, a temperature sensor 13, a thawing layer 14, a heat insulation layer 15 and a thawing tank shell 16; the upper surface of the thawing layer 14 is a concave groove, three small square grooves are formed below the concave groove and used for mounting the temperature sensor 13, a U-shaped through hole is formed in the front side face of the thawing layer 14 and located at a certain thickness below the concave groove and used for mounting the heating plate 12. The periphery and the lower surface of thawing layer 14 are wrapped by thermal-insulating layer 15, thawing tank shell 16 is wrapped on the outer side of thermal-insulating layer 15 and thawing layer 14, and the bottom surface of thawing tank shell 15 is fixedly connected with oscillating plate 8.

The swing mechanism 5 comprises an upper motion part and a lower motion part, the upper motion part is a follow-up mechanism and comprises upper linear guide rails 17 and upper guide rail sliding blocks 18, the upper linear guide rails 17 are fixedly arranged on the lower surface of the top of the upper cover 1, two upper guide rail sliding blocks 18 are arranged on each upper linear guide rail 17, and the swing plate 8 at the upper part is arranged on the upper guide rail sliding blocks 18; the lower motion part is an active mechanism and comprises a lower linear guide rail 19, a lower guide rail slide block 20, a connecting sheet 11, a connecting rod 21, a crank 22 and a motor 23, wherein the two lower linear guide rails 19 are arranged on a supporting plate 9, the two lower guide rail slide blocks 20 are respectively arranged on the two lower linear guide rails 19, a lower swing plate 8 is arranged on the lower guide rail slide block 20, the motor 23 is fixedly arranged on the supporting plate 9, a rotating shaft of the motor is connected with one end of the crank 22, the other end of the crank 22 is connected with one end of the connecting rod 21, the other end of the connecting rod 21 is connected with the center of the lower swing plate 8, the rotating shaft of the motor drives the crank 22 to rotate, the crank drives the connecting rod 21 to do reciprocating linear motion, the connecting rod 21 drives the lower swing plate 8, the lower swing plate 8 drives the lower guide rail slide block 20 to do reciprocating motion on the lower guide rail 19, the upper and lower oscillating plates 8, which reciprocate synchronously, drive the upper and lower thawing grooves 4 connected to them to reciprocate linearly and synchronously, and vibrate the plasma product 7 to be thawed, which is clamped between the upper and lower thawing grooves 4, so that the heating is more uniform.

The buffer mechanism 6 comprises a spring 24, a limit bolt 25 and a spring sleeve 26; spring housing 26 fixed mounting passes spring housing 26 fixed connection box 2 down on backup pad 9, and spring 24 overlaps on spring housing 26, and the one end of spring is passed through spring housing 26 and is realized the elastic support to backup pad 9, and the other end and the interior bottom surface of lower box 2 of spring offset.

The anhydrous dry type plasma heating thawing apparatus of the present invention further comprises an operation interface 3, wherein the operation interface 3 is installed at the front side of the lower case body and is used for setting the heating temperature of each thawing groove 4.

The connecting piece 11 is an L type angle connecting piece, the lower end of the connecting piece is fixed on the lower swing plate 8, and the left and the right of the connecting piece are respectively 1. when the upper cover 1 and the lower box body 2 are buckled, the upper surface of the connecting piece 11 is just propped against the two sides of the upper half thawing groove 4, so that the upper half part and the lower half part of the thawing groove 4 can be driven to synchronously swing when swinging.

The invention has the beneficial effects that:

the invention gets rid of the restriction of the traditional water as a heat-conducting medium, innovatively introduces the nanometer heating plate adopting world first-level heat energy technology, and is matched with the latest PID temperature control system, the heating plate 12 is groove-shaped, the temperature uniformity can reach +/-0.5 ℃, and the temperature control precision of the temperature controller can reach +/-0.1 ℃. The zinc-aluminum alloy is used as a heat-conducting medium, namely the thawing layer 14, and has the advantages of high heat conduction speed, uniform temperature distribution and the like. The design can increase the contact area of the heat-conducting medium and the plasma bag and improve the thawing efficiency. The added buffer mechanism 6 can continuously adjust the contact surface in the plasma melting process. Swing mechanism 5 can be effectual assurance plasma bag inside temperature even to and prevented the appearance of coagulum, guarantee plasma quality of unfreezing, accelerate the plasma intensification. The thawing grooves 4 with different sizes can thaw surgical liquid with different sizes, and the function is comprehensive. Adopt single groove accuse temperature to unfreeze can with the different temperature of design to different unfreezing requirements to the liquid unfreezing of single operation, the energy saving improves the efficiency of unfreezing.

Drawings

Fig. 1 shows the opened state of the dry plasma heating thawing apparatus of the anhydrous type.

FIG. 2 shows the dry plasma heating and thawing on anhydrous scale with the apparatus closed.

Fig. 3 is an exploded view of the defrosting tank.

Fig. 4 shows the upper moving part of the swing mechanism.

Fig. 5 shows the lower moving part of the swing mechanism.

Fig. 6 is an exploded view of the damping mechanism.

Detailed Description

The invention is further described below with reference to the figures and examples.

As shown in fig. 1-6.

A water-free dry type plasma heating unfreezing instrument comprises an upper cover 1, a lower box body 2, unfreezing grooves 4, a swing mechanism 5, a buffer mechanism 6 and an operation interface 3, wherein the operation interface 3 is installed on the front side of the lower box body 2, a display screen and operation buttons are embedded in the inclined plane of the operation interface 3 and used for setting the heating temperature of each unfreezing groove 4, and some electric appliances can be placed inside the operation interface. The upper cover 1 is connected with the lower box body 2 through the parallel connecting rod 10, when the parallel connecting rod 10 is supported (as shown in figure 1), the upper cover 1 is separated from the lower box body 2 and drives the upper half thawing groove 4 and the lower half thawing groove 4 which are symmetrically arranged and are respectively arranged in the upper cover and the lower box body to be separated so as to be convenient for placing the plasma products 7 to be thawed, and the electric heating plates 12 are respectively arranged in the upper half thawing groove 4 and the lower half thawing groove 4; when the parallel connecting rod 10 is folded into a horizontal state (as shown in fig. 2), the upper cover 2 and the lower box body 2 are buckled into a whole; the swing mechanism 5 is divided into an upper moving part and a lower moving part which are respectively arranged in the upper cover 1 and the lower box body 2, and the upper moving part and the lower moving part are connected through a connecting sheet 11 to realize synchronous movement; the upper half and the lower half of the unfreezing groove 4 are respectively arranged on the corresponding upper and lower swing plates 8 and are driven by the swing mechanism 5 to do reciprocating motion; the lower moving part of the swing mechanism 5 is arranged on a support plate 9, the support plate 9 is supported on a buffer mechanism 6, and the buffer mechanism 6 is arranged in the lower box body 2; various electrical devices are mounted below the support plate 9. The inside of the two sides of the upper cover 1 is provided with a connecting rotating shaft connected with a parallel connecting rod 10. The front side of the lower box body 2 is provided with a through hole for convenient wiring. The outside of the two sides of the connecting rod is provided with a connecting rotating shaft which is connected with a parallel connecting rod 10. The number of the parallel connecting rods 10 is 4, and the two rear side connecting rods are provided with wiring grooves, so that the upper unfreezing groove 4 can be conveniently wired to the lower box body 2.

The capacity and the number of the unfreezing tanks 4 can be configured according to the size and the number of the liquid bags to be unfrozen, and the unfreezing tanks are matched up and down and have symmetrical structures. Each half of the thawing groove 4 comprises a heating plate 12, a temperature sensor 13, a thawing layer 14, a heat insulation layer 15 and a thawing groove shell 16, as shown in figure 3; the upper surface of the thawing layer 14 is a concave groove, three small square grooves are formed below the concave groove and used for mounting the temperature sensor 13, a U-shaped through hole is formed in the front side face of the thawing layer 14 and located at a certain thickness below the concave groove and used for mounting the heating plate 12. The periphery and the lower surface of thawing layer 14 are wrapped by thermal-insulating layer 15, thawing tank shell 16 is wrapped on the outer side of thermal-insulating layer 15 and thawing layer 14, and the bottom surface of thawing tank shell 15 is fixedly connected with oscillating plate 8.

The swing mechanism 5 of the invention comprises an upper motion part and a lower motion part, as shown in fig. 4 and 5, the upper motion part (fig. 4) is a follow-up mechanism and comprises upper linear guide rails 17 and upper guide rail sliding blocks 18, the upper linear guide rails 17 are fixedly arranged on the lower surface of the top of the upper cover 1, two upper guide rail sliding blocks 18 are arranged on each upper linear guide rail 17, and the swing plate 8 at the upper part is arranged on the upper guide rail sliding blocks 18; the lower motion part (figure 5) is an active mechanism, which comprises a lower linear guide rail 19, a lower guide rail slide block 20, a connecting sheet 11, a connecting rod 21, a crank 22, a motor 23 and a connecting sheet 11, wherein the two lower linear guide rails 19 are arranged on a supporting plate 9, the two lower guide rail slide blocks 20 are respectively arranged on the two lower linear guide rails, a lower swing plate 8 is arranged on the lower guide rail slide block 20, the motor 23 is fixedly arranged on the supporting plate 9, the rotating shaft of the motor is connected with one end of the crank 22, the other end of the crank 22 is connected with one end of the connecting rod 21, the other end of the connecting rod 21 is connected with the center of the lower swing plate 8, the rotating shaft of the motor drives the crank 22 to rotate, the crank drives the connecting rod 21 to do reciprocating linear motion, the connecting rod 21 drives the lower swing plate 8, the lower swing plate 8 drives the lower guide, the upper guide rail slide block 18 is driven to reciprocate along the upper linear guide rail 17, the upper part and the lower part of the swinging plate 8 which synchronously reciprocates drive the upper half thawing groove 4 and the lower half thawing groove 4 which are connected with the upper guide rail slide block and the lower guide rail slide block to synchronously reciprocate linearly, and the plasma product 7 which is clamped between the upper half thawing groove 4 and the lower half thawing groove 4 and needs to be thawed is vibrated, so that the heating is more uniform. The connecting piece 11 is fixed on the lower swing plate 8, when the upper cover 1 and the lower box body 2 are buckled, the upper part of the connecting piece just props against the two sides of the upper half thawing groove 4, so that the upper half part and the lower half part of the thawing groove 4 can be driven to synchronously swing when swinging.

The buffer mechanism 6 of the present invention is shown in fig. 6, and comprises a spring 24, a limit bolt 25, and a spring housing 26; spring housing 26 fixed mounting passes spring housing 26 fixed connection box 2 down on backup pad 9, and spring 24 overlaps on spring housing 26, and the one end of spring is passed through spring housing 26 and is realized the elastic support to backup pad 9, and the other end and the interior bottom surface of lower box 2 of spring offset.

The details are as follows:

referring to fig. 1, the waterless dry-type heating thawing apparatus of the present invention includes an upper cover 1, a lower case 2, an operation interface 3, a thawing tank 4, a swing mechanism 5, and a buffer mechanism 6.

With reference to fig. 2, when the device is closed, the cover 1 rests on the support edge 27, the support edge 27 being provided with notches which cooperate with the lower edge of the cover 1 to limit the movement of the cover 1 in a horizontal plane. The cover 1 presses on the supporting edge 27 by its own weight, closing the device. The two sides of the closed upper cover 1 are held by two pressing hands, and the closed upper cover 1 is opened to the state shown in figure 1 by upward force, at the moment, the two front parallel connecting rods 10 abut against the front edge of the upper cover 1 to limit the movement of the upper cover 1, and at the moment, the upper cover 1 is in an opened state.

Referring to fig. 3, the capacity and the number of the thawing grooves 4 in the present invention can be configured according to the size and the number of the liquid bags to be thawed. The device comprises a heating plate 12, a temperature sensor 13, a thawing layer 14, a heat insulation layer 15 and a thawing groove shell 16. The upper surface of the thawing layer 14 is a concave groove, three small square grooves are formed below the concave groove and used for mounting the temperature sensor 13, a U-shaped through hole is formed in the front side face of the thawing layer 14 and located at a certain thickness below the concave groove and used for mounting the heating plate 12. The thermal insulation layer 15 wraps the periphery and the lower surface of the thawing layer 14. The thawing tank shell 16 is wrapped outside the thermal insulation layer 15 and the thawing layer 14. In the open state, the plasma bag 7 is placed in the lower thawing tank 4, the thawing temperature is input and set by the buttons on the operation interface 3, and each tank is independently controlled in temperature.

Referring to fig. 4 and 5, the swing mechanism 5 of the present invention includes an upper moving portion and a lower moving portion. The upper moving part is a follow-up mechanism and comprises upper linear guide rails 17, upper guide rail sliding blocks 18 and a swinging plate 8, the upper linear guide rails 17 are fixedly arranged on the lower surface of the top of the upper cover 1, two upper guide rail sliding blocks 18 are arranged on each upper linear guide rail 17, and the swinging plate 8 is arranged on the upper guide rail sliding blocks 18. The lower motion part is a driving mechanism and comprises a lower linear guide rail 19, a lower guide rail slide block 20, a swing plate 8, a connecting piece 11, a connecting rod 21, a crank 22 and a motor 23. Two lower linear guide rails 19 are arranged on a supporting plate 9, two lower guide rail sliding blocks 20 are respectively arranged on the lower linear guide rails, a swinging plate 8 is arranged on the lower guide rail sliding blocks 20, a motor 23 is fixedly arranged on the supporting plate 9, a rotating shaft of the motor is connected with one end of a crank 22, the other end of the crank 22 is connected with one end of a connecting rod 21, and the other end of the connecting rod 21 is connected with the center of the swinging plate 8. When equipment is closed, the upper and lower thawing groove 4 is matched, the upper moving part and the lower moving part are connected through the connecting sheet 11, the reciprocating motion of the swinging plate 8 is realized under the driving of the motor 23, the thawing groove 4 is installed on the swinging plate 8 and then swings together, and therefore the swing of the plasma bag 7 is realized.

Referring to fig. 6, the damping mechanism 6 of the present invention includes a spring 24, a limit bolt 25, and a spring housing 26. The spring sleeve 26 is fixedly arranged on the support plate 9, the limiting bolt 25 penetrates through the spring sleeve 26 to be fixedly connected with the lower box body 2, and the spring 24 is sleeved on the spring sleeve 26 and props against the support plate 9 and the lower box body 2. When the device is closed, the upper plasma tank 4 presses on the plasma bag 7, the buffer mechanism 6 plays a vital role in order to prevent the plasma bag 7 from being broken by excessive pressure, and when the pressure is excessive, the spring 24 is compressed, so that the pressure borne by the plasma bag 7 is reduced, and the close fit between the surface of the plasma bag 7 and the surface of the unfreezing layer 14 is ensured.

The related electric appliances according to the present invention are mounted below the lower case 2, and a display and operation buttons are mounted on the operation interface 3. The device can realize the high-efficiency and high-quality unfreezing and heating of blood plasma and other surgical liquid to 37 ℃. The device has the advantages of convenient operation, accurate and flexible temperature control, various functions, sanitation and environmental protection, and has certain auxiliary effects on improving the operation environment, improving the operation efficiency and optimizing the operation effect.

The parts not involved in the present invention are the same as or can be implemented using the prior art.

Claims

1. A dry plasma heating thawing instrument is characterized by comprising an upper cover (1), a lower box body (2), thawing grooves (4), a swinging mechanism (5) and a buffer mechanism (6), wherein the upper cover (1) is connected with the lower box body (2) through a parallel connecting rod (10), when the parallel connecting rod (10) is supported, the upper cover (1) and the lower box body (2) are separated and drive an upper half and a lower half thawing groove (4) which are symmetrically arranged in the upper cover and the lower box body respectively, so that plasma products (7) to be thawed are placed, an electric heating plate (12) is arranged in each upper half and the lower half thawing grooves (4), when the parallel connecting rod (10) is folded into a horizontal state, the upper cover (1) and the lower box body (2) are integrated, the swinging mechanism (5) is divided into an upper moving part and a lower moving part, the upper sliding guide rail (1) and the lower sliding guide rail (2) are respectively arranged in the upper cover (1) and lower box body (2), the upper sliding guide rail (2) and the lower sliding guide rail (2) are connected with the lower sliding guide rail (2), the upper sliding plate (7) and the lower sliding plate (2), the sliding plate (6) is driven by the upper sliding plate (7) and the sliding plate (2), the sliding plate (7) and the sliding plate (2) are driven by the sliding plate (2), the sliding plate (7) and the sliding plate (2), the sliding plate (2) are driven by the sliding plate (2), the sliding plate (7) and the sliding plate (2), the sliding plate (7) are driven by the sliding plate (7) and the sliding plate (2), the sliding plate (2) are arranged in the sliding plate, the sliding plate (7) are driven by the sliding plate, the sliding plate (7) is driven by the sliding plate (2), the sliding plate (7) is driven by the sliding plate, the sliding plate (7) is arranged in the sliding plate, the sliding plate (7) and the sliding plate, the sliding plate is driven by the sliding plate, the sliding plate is arranged in the sliding plate, the sliding plate is fixed, the sliding plate is arranged in the sliding plate, the sliding plate is fixed, the sliding plate is fixed, the sliding plate is fixed guide rail, the sliding plate is fixed, the sliding plate.

2. The non-aqueous dry type plasma heating/thawing apparatus according to claim 1, further comprising an operation interface (3), wherein the operation interface (3) is installed at a front side of the lower housing for setting a heating temperature of each thawing tank (4).