CN107397897A - A kind of Chinese patent drug for treating children's diphtheria and preparation method thereof - Google Patents

A kind of Chinese patent drug for treating children's diphtheria and preparation method thereof Download PDF

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CN107397897A
CN107397897A CN201610344677.6A CN201610344677A CN107397897A CN 107397897 A CN107397897 A CN 107397897A CN 201610344677 A CN201610344677 A CN 201610344677A CN 107397897 A CN107397897 A CN 107397897A
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parts
diphtheria
hardships
decoction
herb
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陈茹
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    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/02Algae
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    • AHUMAN NECESSITIES
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/744Gardenia
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    • A61K36/75Rutaceae (Rue family)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964Anemarrhena
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention discloses a kind of Chinese patent drug for treating children's diphtheria, it is prepared from the following raw materials in parts by weight:70 120 parts of 7 16 parts of Radix picrorrhizae, 8 20 parts of radix stellariae dichotomae, 7 16 parts of Japanese Cayratia Herb, 7 18 parts of hardships tree, 5 17 parts of Folium Sauropi, 4 13 parts of hedge column, 5 12 parts of three forks hardship, 5 12 parts of pipewort, 5 17 parts of sheepear inula herb, 2 11 parts of Cissus repens, 3 14 parts of aster, 3 14 parts of kelp, 3 10 parts of emblic, 4 14 parts of lingnania chugii, 3 12 parts of the fruit of summer cypress, 29 parts of Semen Lablab Album, 16 parts of seven leaf courage, 3 15 parts of cape jasmine, 2 11 parts of balloonflower root, 3 10 parts of the wind-weed and fish glue.The medicament of the present invention is compared with existing medicament, and the state of an illness is improved in a short time, and long-term use can make the state of an illness be eased, evident in efficacy.

Description

A kind of Chinese patent drug for treating children's diphtheria and preparation method thereof
Technical field
The present invention relates to a kind of Chinese patent drug for treating children's diphtheria and preparation method thereof, belong to tcm field.
Background technology
Diphtheria can be divided into four types, and pharyngeal diphtheria, diphtheria laryngis, nasal diphtheria and the diphtheria at other positions are followed successively by by its incidence. Adult and older children are in the majority with pharyngeal diphtheria, and other kinds of diphtheria is more common in child;It is slight that this disease may be always maintained at symptom, During deterioration, dysphagia, toxaemia sign and collapse start substantially, and edema of throat can hinder breathing, if pseudomembrane, which is invaded, arrives larynx, Trachea and bronchus, respiratory tract partial blockage may be made, or come off suddenly and cause complete obstruction.Cervical lymph adenoncus, In several cases, exotoxin permeates into neck tissue and causes serious oedema, if pharynx nasalis is invaded, nasal cavity outflow slurries blood Property nasal mucus, often for one side.Cutaneous diphtheria is damaged without specific shape, is damaged occurred in four limbs, if untreated, Ke Nengyou Infiltrated in local toxin and engender stolidity, can also there is a typical local pain, tenderness and is oozed out at erythema, and skin is white Group A β-haemolytic streptococci or/and staphylococcus aureus are generally also concealed at larynx infringement, pseudomembrane is rare, there is 20%~40% Case merge same bion corynebacterium diphtheriae nasopharyngeal infections;The infection of eye corynebacterium diphtheriae is rare, and may occur or not occur Other skin lesions, infection may be produced at the mucocutaneous place such as ear, the suppurative and exedens perineum vaginitis of genital tract. The medicine of existing treatment children's diphtheria, because children physical qualification limits, side effect is relatively large, and particularly antibiotic makes Had a great influence with to children's autoantibody.
The content of the invention
In view of the deficienciess of the prior art, treated the technical problem to be solved by the invention is to provide a kind of in children's diphtheria Patent medicine and preparation method thereof, therapeutic effect is good, and side effect is low, and cost is cheap, safe to use.
In order to solve the above technical problems, the present invention adopts the technical scheme that, a kind of Chinese patent drug for treating children's diphtheria, by following The raw material of parts by weight is made:Radix picrorrhizae 7-16 parts, radix stellariae dichotomae 8-20 parts, Japanese Cayratia Herb 7-16 parts, hardships tree 7-18 parts, Folium Sauropi 5-17 parts, hedge column 4-13 parts, three fork hardship 5-12 parts, pipewort 5-12 parts, sheepear inula herb 5-17 parts, Cissus repens 2-11 parts, aster 3-14 parts, kelp 3-14 parts, emblic 3-10 parts, lingnania chugii 4-14 parts, fruit of summer cypress 3-12 parts, Semen Lablab Album 2-9 parts, seven leaf courage 1-6 parts, cape jasmine 3-15 parts, balloonflower root 2-11 parts, wind-weed 3-10 parts and fish glue 70-120 parts.
Optimization, the Chinese patent drug of above-mentioned treatment children diphtheria, it is prepared from the following raw materials in parts by weight:Radix picrorrhizae 8-12 parts, Radix stellariae dichotomae 10-15 parts, Japanese Cayratia Herb 9-12 parts, hardships tree 9-15 parts, Folium Sauropi 7-12 parts, hedge column 6-11 parts, three forks are bitter It is 7-10 parts, pipewort 8-11 parts, sheepear inula herb 7-13 parts, Cissus repens 5-8 parts, aster 6-10 parts, kelp 6-10 parts, remaining Sweet sub- 4-8 parts, lingnania chugii 6-12 parts, fruit of summer cypress 5-10 parts, Semen Lablab Album 3-7 parts, seven leaf courage 2-5 parts, cape jasmine 5-10 parts, Balloonflower root 4-8 parts, wind-weed 5-9 parts and fish glue 80-110 parts.
Optimization, the Chinese patent drug of above-mentioned treatment children diphtheria, it is prepared from the following raw materials in parts by weight:10 parts of Radix picrorrhizae, silver 11 parts of radix bupleuri, 10 parts of Japanese Cayratia Herb, 12 parts of hardships tree, 8 parts of Folium Sauropi, 9 parts of hedge column, three forks are bitter 8 parts, 9 parts of pipewort, 10 parts of sheepear inula herb, 6 parts of Cissus repens, 7 parts of aster, 7 parts of kelp, 6 parts of emblic, 10 parts of lingnania chugii, 7 parts of the fruit of summer cypress, 105 parts of 5 parts of Semen Lablab Album, 3 parts of seven leaf courage, 6 parts of cape jasmine, 6 parts of balloonflower root, 6 parts of the wind-weed and fish glue.
A kind of preparation method for the Chinese patent drug for treating children's diphtheria, is made up of following steps:
(1) half that Radix picrorrhizae, hardships tree, three fork hardships, sheepear inula herb, the fruit of summer cypress and Semen Lablab Album are taken out to total amount is crushed, It is ground into 200-300 targeted fine powders;
(2) after remaining starting material with water is soaked 24 hours, decoct to discharge reduction 2/3rds;
(3) remove the dregs of a decoction and stay decoction, water boiling 8 hours again are added in decoction;
(4) decoction after boiling is heated to pasty state at a temperature of 75 degrees Celsius;
(5) fine powder of step (1) is poured into the pasty state decoction after the completion of step (4), fish glue is added after being stirred, Bottled after being stirred stand-by.
The medicament of the present invention is compared with existing medicament, and the state of an illness is improved in a short time, and long-term use can obtain the state of an illness Alleviate, it is evident in efficacy;Radix picrorrhizae:Enter liver, stomach, large intestine footpath.Function removing damp-heat, disappear infantile malnutrition due to digestive disturbances or intestinalparasites.Radix stellariae dichotomae:Clearing heat and cooling blood, remove Hectic fever due to yin.Japanese Cayratia Herb:It is clearing heat and detoxicating, cooling blood and hemostasis, clearing heat for detumescence, activating blood circulation and reducing swelling.Hardships tree:Heat-clearing, dissipate the stasis of blood.Folium Sauropi: Moisten the lung and relieve the cough.Hedge column:Clear hot summer weather, removing heat from the liver.Three forks are bitter:Clearing heat and detoxicating, bone fire, desinsection.Pipewort:Wind and heat dispersing, Removing nebula.Cure mainly blind mesh screen, sparrow, headache, dentalgia, larynx numbness.Sheepear inula herb:Wind-dispelling, dampness removing, promoting the circulation of qi, change stagnant.White powder Rattan:Heat-clearing dissipates poison relieves pain.Aster:Under moistening lung its, stopping coughing and removing phlegm.Kelp:Softening and resolving hard mass, dissolving phlegm heat-clearing.Emblic:Drop Fiery heat-clearing, eliminating phlegm dissipate poison, cool blood.Lingnania chugii:Clearing lung-heat, clearing away the heart-fire, diuresis.The fruit of summer cypress:Clearing away damp-heat, diuresis.It is white flat Beans:Invigorating the spleen for eliminating dampness, and in relieve summer heat.Seven leaf courages:Expelling phlegm and arresting coughing, mental-tranquilization, tonifying middle-Jiao and Qi.Cape jasmine:Enter the heart, liver, lung, Stomach.Guiding drug.Balloonflower root:Enter lung channel, guiding drug.The wind-weed:Enter lung, kidney, stomach three passes through, guiding drug.The medicament of the present invention Preparation technology has that preparation technology is simple, stably and is easy to grasp, equipment is simple, reduced investment, the simple to operate, production cycle The advantages that short, commercial family expenses.
Embodiment
Embodiment 1
The present invention is a kind of Chinese patent drug for treating children's diphtheria, is prepared from the following raw materials in parts by weight:7 parts of Radix picrorrhizae, Yin Chai 8 parts recklessly, 7 parts of Japanese Cayratia Herb, 7 parts of hardships tree, 5 parts of Folium Sauropi, 4 parts of hedge column, three forks are bitter 5 parts, 5 parts of pipewort, white It is 5 parts of ox courage, 2 parts of Cissus repens, 3 parts of aster, 3 parts of kelp, 3 parts of emblic, 4 parts of lingnania chugii, 3 parts of the fruit of summer cypress, white 70 parts of 2 parts of French beans, 1 part of seven leaf courage, 3 parts of cape jasmine, 2 parts of balloonflower root, 3 parts of the wind-weed and fish glue.
A kind of preparation method for the Chinese patent drug for treating children's diphtheria, is made up of following steps:
(1) half that Radix picrorrhizae, hardships tree, three fork hardships, sheepear inula herb, the fruit of summer cypress and Semen Lablab Album are taken out to total amount is crushed, It is ground into 200-300 targeted fine powders;
(2) after remaining starting material with water is soaked 24 hours, decoct to discharge reduction 2/3rds;
(3) remove the dregs of a decoction and stay decoction, water boiling 8 hours again are added in decoction;
(4) decoction after boiling is heated to pasty state at a temperature of 75 degrees Celsius;
(5) fine powder of step (1) is poured into the pasty state decoction after the completion of step (4), fish glue is added after being stirred, Bottled after being stirred stand-by.
The medicament of the present invention is compared with existing medicament, and the state of an illness is improved in a short time, and long-term use can obtain the state of an illness Alleviate, it is evident in efficacy;Radix picrorrhizae:Enter liver, stomach, large intestine footpath.Function removing damp-heat, disappear infantile malnutrition due to digestive disturbances or intestinalparasites.Radix stellariae dichotomae:Clearing heat and cooling blood, Except hectic fever due to yin.Japanese Cayratia Herb:It is clearing heat and detoxicating, cooling blood and hemostasis, clearing heat for detumescence, activating blood circulation and reducing swelling.Hardships tree:Heat-clearing, dissipate the stasis of blood.Imperial Lei Leaf:Moisten the lung and relieve the cough.Hedge column:Clear hot summer weather, removing heat from the liver.Three forks are bitter:Clearing heat and detoxicating, bone fire, desinsection.Pipewort:Dispelling wind Heat-clearing, removing nebula.Cure mainly blind mesh screen, sparrow, headache, dentalgia, larynx numbness.Sheepear inula herb:Wind-dispelling, dampness removing, promoting the circulation of qi, change stagnant. Cissus repens:Heat-clearing dissipates poison relieves pain.Aster:Under moistening lung its, stopping coughing and removing phlegm.Kelp:Softening and resolving hard mass, dissolving phlegm heat-clearing.Emblic: Fall fire heat-clearing, eliminating phlegm dissipate poison, cool blood.Lingnania chugii:Clearing lung-heat, clearing away the heart-fire, diuresis.The fruit of summer cypress:Clearing away damp-heat, diuresis.In vain French beans:Invigorating the spleen for eliminating dampness, and in relieve summer heat.Seven leaf courages:Expelling phlegm and arresting coughing, mental-tranquilization, tonifying middle-Jiao and Qi.Cape jasmine:Enter the heart, liver, Lung, stomach.Guiding drug.Balloonflower root:Enter lung channel, guiding drug.The wind-weed:Enter lung, kidney, stomach three passes through, guiding drug.The present invention's Medicament preparation technology has that preparation technology is simple, stably and is easy to grasp, equipment is simple, reduced investment, simple to operate, production The advantages that cycle is short, commercial family expenses.
Embodiment 2
The present invention is a kind of Chinese patent drug for treating children's diphtheria, is prepared from the following raw materials in parts by weight:16 parts of Radix picrorrhizae, silver 20 parts of radix bupleuri, 16 parts of Japanese Cayratia Herb, 18 parts of hardships tree, 17 parts of Folium Sauropi, 13 parts of hedge column, three forks bitter 12 parts, pipewort 12 parts, 17 parts of sheepear inula herb, 11 parts of Cissus repens, 14 parts of aster, 14 parts of kelp, 10 parts of emblic, 14 parts of lingnania chugii, 120 parts of 12 parts of the fruit of summer cypress, 9 parts of Semen Lablab Album, 6 parts of seven leaf courage, 15 parts of cape jasmine, 11 parts of balloonflower root, 10 parts of the wind-weed and fish glue.
A kind of preparation method for the Chinese patent drug for treating children's diphtheria, is made up of following steps:
(1) half that Radix picrorrhizae, hardships tree, three fork hardships, sheepear inula herb, the fruit of summer cypress and Semen Lablab Album are taken out to total amount is crushed, It is ground into 200-300 targeted fine powders;
(2) after remaining starting material with water is soaked 24 hours, decoct to discharge reduction 2/3rds;
(3) remove the dregs of a decoction and stay decoction, water boiling 8 hours again are added in decoction;
(4) decoction after boiling is heated to pasty state at a temperature of 75 degrees Celsius;
(5) fine powder of step (1) is poured into the pasty state decoction after the completion of step (4), fish glue is added after being stirred, Bottled after being stirred stand-by.
Embodiment 3
The present invention is a kind of Chinese patent drug for treating children's diphtheria, is prepared from the following raw materials in parts by weight:10 parts of Radix picrorrhizae, silver 11 parts of radix bupleuri, 10 parts of Japanese Cayratia Herb, 12 parts of hardships tree, 8 parts of Folium Sauropi, 9 parts of hedge column, three forks are bitter 8 parts, 9 parts of pipewort, 10 parts of sheepear inula herb, 6 parts of Cissus repens, 7 parts of aster, 7 parts of kelp, 6 parts of emblic, 10 parts of lingnania chugii, 7 parts of the fruit of summer cypress, 105 parts of 5 parts of Semen Lablab Album, 3 parts of seven leaf courage, 6 parts of cape jasmine, 6 parts of balloonflower root, 6 parts of the wind-weed and fish glue.
A kind of preparation method for the Chinese patent drug for treating children's diphtheria, is made up of following steps:
(1) half that Radix picrorrhizae, hardships tree, three fork hardships, sheepear inula herb, the fruit of summer cypress and Semen Lablab Album are taken out to total amount is crushed, It is ground into 200-300 targeted fine powders;
(2) after remaining starting material with water is soaked 24 hours, decoct to discharge reduction 2/3rds;
(3) remove the dregs of a decoction and stay decoction, water boiling 8 hours again are added in decoction;
(4) decoction after boiling is heated to pasty state at a temperature of 75 degrees Celsius;
(5) fine powder of step (1) is poured into the pasty state decoction after the completion of step (4), fish glue is added after being stirred, Bottled after being stirred stand-by.
Certainly, described above is not limitation of the present invention, and the present invention is also not limited to the example above, the art it is general Logical technical staff, in the essential scope of the present invention, the variations, modifications, additions or substitutions made should all belong to the present invention's Protection domain.

Claims (4)

  1. A kind of 1. Chinese patent drug for treating children's diphtheria, it is characterised in that:It is prepared from the following raw materials in parts by weight:Radix picrorrhizae 7-16 Part, radix stellariae dichotomae 8-20 parts, Japanese Cayratia Herb 7-16 parts, hardships tree 7-18 parts, Folium Sauropi 5-17 parts, hedge column 4-13 parts, three forks Bitter 5-12 parts, pipewort 5-12 parts, sheepear inula herb 5-17 parts, Cissus repens 2-11 parts, aster 3-14 parts, kelp 3-14 parts, Emblic 3-10 parts, lingnania chugii 4-14 parts, fruit of summer cypress 3-12 parts, Semen Lablab Album 2-9 parts, seven leaf courage 1-6 parts, cape jasmine 3-15 Part, balloonflower root 2-11 parts, wind-weed 3-10 parts and fish glue 70-120 parts.
  2. 2. the Chinese patent drug for the treatment of children's diphtheria according to claim 1, it is characterised in that:By the original of following parts by weight Material is made:Radix picrorrhizae 8-12 parts, radix stellariae dichotomae 10-15 parts, Japanese Cayratia Herb 9-12 parts, hardships tree 9-15 parts, Folium Sauropi 7-12 Part, hedge column 6-11 parts, three fork hardship 7-10 parts, pipewort 8-11 parts, sheepear inula herb 7-13 parts, Cissus repens 5-8 parts, aster 6-10 parts, kelp 6-10 parts, emblic 4-8 parts, lingnania chugii 6-12 parts, fruit of summer cypress 5-10 parts, Semen Lablab Album 3-7 parts, Seven leaf courage 2-5 parts, cape jasmine 5-10 parts, balloonflower root 4-8 parts, wind-weed 5-9 parts and fish glue 80-110 parts.
  3. 3. the Chinese patent drug for the treatment of children's diphtheria according to claim 2, it is characterised in that:By the original of following parts by weight Material is made:10 parts of Radix picrorrhizae, 11 parts of radix stellariae dichotomae, 10 parts of Japanese Cayratia Herb, 12 parts of hardships tree, 8 parts of Folium Sauropi, 9 parts of hedge column, Three forks are bitter 8 parts, 9 parts of pipewort, 10 parts of sheepear inula herb, 6 parts of Cissus repens, 7 parts of aster, 7 parts of kelp, 6 parts of emblic, 10 parts of lingnania chugii, 7 parts of the fruit of summer cypress, 5 parts of Semen Lablab Album, 3 parts of seven leaf courage, 6 parts of cape jasmine, 6 parts of balloonflower root, 6 parts of the wind-weed and fish 105 parts of glue.
  4. A kind of 4. preparation method of the Chinese patent drug for the treatment of children's diphtheria of any one in claim 1-3, it is characterised in that: It is made up of following steps:
    (1) half that Radix picrorrhizae, hardships tree, three fork hardships, sheepear inula herb, the fruit of summer cypress and Semen Lablab Album are taken out to total amount is crushed, It is ground into 200-300 targeted fine powders;
    (2) after remaining starting material with water is soaked 24 hours, decoct to discharge reduction 2/3rds;
    (3) remove the dregs of a decoction and stay decoction, water boiling 8 hours again are added in decoction;
    (4) decoction after boiling is heated to pasty state at a temperature of 75 degrees Celsius;
    (5) fine powder of step (1) is poured into the pasty state decoction after the completion of step (4), fish glue is added after being stirred, Bottled after being stirred stand-by.
CN201610344677.6A 2016-05-21 2016-05-21 A kind of Chinese patent drug for treating children's diphtheria and preparation method thereof Pending CN107397897A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435944A (en) * 2014-12-24 2015-03-25 刘安利 Traditional Chinese medicine composition for treating infantile cough and preparation method thereof
CN105582374A (en) * 2015-10-21 2016-05-18 孙明忠 Chinese patent medicine for treating diphtheria and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435944A (en) * 2014-12-24 2015-03-25 刘安利 Traditional Chinese medicine composition for treating infantile cough and preparation method thereof
CN105582374A (en) * 2015-10-21 2016-05-18 孙明忠 Chinese patent medicine for treating diphtheria and preparation method thereof

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