CN107376003A - One kind is used to treat dermopathic medical dressing - Google Patents

One kind is used to treat dermopathic medical dressing Download PDF

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Publication number
CN107376003A
CN107376003A CN201710502327.2A CN201710502327A CN107376003A CN 107376003 A CN107376003 A CN 107376003A CN 201710502327 A CN201710502327 A CN 201710502327A CN 107376003 A CN107376003 A CN 107376003A
Authority
CN
China
Prior art keywords
sodium hyaluronate
parts
medical dressing
treat dermopathic
dermopathic medical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201710502327.2A
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Chinese (zh)
Inventor
马英祥
姜晓筑
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chengdu Jiabaoxiang Biological Technology Co Ltd
Original Assignee
Chengdu Jiabaoxiang Biological Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Priority to CN201710502327.2A priority Critical patent/CN107376003A/en
Publication of CN107376003A publication Critical patent/CN107376003A/en
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0014—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0019—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0033—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/21—Acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23—Carbohydrates
    • A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

It is used to treat dermopathic medical dressing the invention discloses one kind, it is described to include following components for treating dermopathic medical dressing：EDTA 2Na, glycerine, Sodium Hyaluronate, oligomerization Sodium Hyaluronate, poly-aspartate, trehalose, xanthan gum, glycine betaine, methyl propanediol, carbomer, triethanolamine, parahydroxyacet-ophenone, 1,2- hexylene glycol, 1,3-BDO, collagen protein powder, alpha-hydroxy acid.Cytotoxicity of the present invention is small, has preferable therapeutic effect to acne.

Description

One kind is used to treat dermopathic medical dressing
Technical field
The present invention relates to the technical field of skin dressing.
Background technology
Acne, whelk, acne, dark sore etc. are commonly called as, pathogenesis is more complicated, is current dept. of dermatology and common and more refractory The disease of skin for the treatment of, especially easily produced in face, have a strong impact on image appearance.
The content of the invention
It is a kind of small available for acne treatment, cytotoxicity it is an object of the invention to propose, it is safe, it can be applicable simultaneously In general population or dept. of dermatology's sufferer be used for treat dermopathic medical dressing.
Technical scheme is as follows：
One kind is used to treat dermopathic medical dressing, and it includes following components：EDTA-2Na, glycerine, Sodium Hyaluronate, oligomerization Sodium Hyaluronate, poly-aspartate, trehalose, xanthan gum, glycine betaine, methyl propanediol, carbomer, triethanolamine, to hydroxyl Acetophenone, 1,2 hexylene glycol, 1,3-BDO, collagen protein powder, 'alpha '-hydroxy acids.
Preferably：The Sodium Hyaluronate is middle numerator sodium hyaluronate.
It is also preferred that：The carbomer is Carbopol 941.
It is also preferred that：Its in parts by mass, including following components：EDTA-2Na0.04 ~ 0.08 part, glycerine 2.0 ~ 6.0 parts, middle 0.01 ~ 0.04 part of numerator sodium hyaluronate, 0.02 ~ 0.06 part of oligomerization Sodium Hyaluronate, poly-aspartate 0.6 ~ 1.0 Part, 0.2 ~ 0.6 part of trehalose, 0.01 ~ 0.05 part of xanthan gum, 0.6 ~ 1.0 part of glycine betaine, 2.0 ~ 6.0 parts of methyl propanediol, card 10.0 ~ 20.0 parts of 1% aqueous dispersion of ripple nurse 941,0.08 ~ 0.16 part of triethanolamine, 0.2 ~ 0.8 part of parahydroxyacet-ophenone, 1,2 0.2 ~ 0.8 part of hexylene glycol, 2.0 ~ 6.0 parts of 1,3-BDO, 0.08 ~ 0.2 part of collagen protein powder, 'alpha '-hydroxy acids 0.01 ~ 0.15 Part.
'alpha '-hydroxy acids can carry out acne treatment in the present invention, after the treatment be removed the skin of disease site, thereafter Collagen can carry out skin repair；Parahydroxyacet-ophenone, 1,2 hexylene glycols can prevent microbial growth, in making for the present invention , stimulation non-toxic to skin, sensitivity response, safe under amount；Glycerine, middle numerator sodium hyaluronate, oligomerization Sodium Hyaluronate, Poly-aspartate, trehalose, 1,3-BDO are used cooperatively, i.e., can play moisturizing, lubrication, can be promoted again other The performance of composition function；Xanthan gum, carbomer can increase solution viscosity, solution is kept hydrogel state；Triethanolamine Effectively regulation solution ph；EDTA-2Na may keep solution-stabilized, it is not gone bad.
The present invention has fabulous therapeutic effect to acne, and safe, cytotoxicity is small to can be used for general population, and skin The acne sufferer of skin section, and there is good skin repair function.
Embodiment
Embodiment 1
（1）EDTA-2Na, glycerine, middle numerator sodium hyaluronate, oligomerization Sodium Hyaluronate, poly-aspartate, trehalose is taken to add In water, stirring and dissolving；
（2）Add xanthan gum, glycine betaine, methyl propanediol and step（1）Obtained mixed solution is uniformly mixed；
（3）Carbopol 941 is taken to be formulated as 1% aqueous dispersion, by itself and step（2）Obtained mixed solution remixes uniformly；
（4）Separately take triethanolamine, parahydroxyacet-ophenone, 1,2 hexylene glycols, 1,3 butylene glycol, collagen protein powder respectively in water It is uniformly dissolved, with step（4）Obtained mixed solution remixes uniformly；
（5）By step（4）Obtained mixed solution low temperature distillation to sticky pasty state, thereafter addition 'alpha '-hydroxy acids stirs, Obtain described for treating dermopathic medical dressing；
Wherein each material quality part is：EDTA-2Na0.04 parts, 2.0 parts of glycerine, middle 0.01 part of numerator sodium hyaluronate, oligomerization is saturating Bright 0.02 part of matter acid sodium, 0.6 part of poly-aspartate, 0.2 part of trehalose, 0.01 part of xanthan gum, 0.6 part of glycine betaine, methyl-prop two Alcohol 2.0,10.0 parts of 1% aqueous dispersion of Carbopol 941,0.08 part of triethanolamine, 0.2 part of parahydroxyacet-ophenone, 1,2 oneself two 0.2 part of alcohol, 2.0 parts of 1,3-BDO, 0.08 part of collagen protein powder, 0.01 part of 'alpha '-hydroxy acids.
Embodiment 2
（1）EDTA-2Na, glycerine, middle numerator sodium hyaluronate, oligomerization Sodium Hyaluronate, poly-aspartate, trehalose is taken to add In water, stirring and dissolving；
（2）Add xanthan gum, glycine betaine, methyl propanediol and step（1）Obtained mixed solution is uniformly mixed；
（3）Carbopol 941 is taken to be formulated as 1% aqueous dispersion, by itself and step（2）Obtained mixed solution remixes uniformly；
（4）Separately take triethanolamine, parahydroxyacet-ophenone, 1,2 hexylene glycols, 1,3 butylene glycol, collagen protein powder respectively in water It is uniformly dissolved, with step（4）Obtained mixed solution remixes uniformly；
（5）By step（4）Obtained mixed solution low temperature distillation to sticky pasty state, thereafter addition 'alpha '-hydroxy acids stirs, Obtain described for treating dermopathic medical dressing；
Wherein each material quality part is：EDTA-2Na0.08 parts, 6.0 parts of glycerine, middle 0.04 part of numerator sodium hyaluronate, oligomerization is saturating Bright 0.06 part of matter acid sodium, 1.0 parts of poly-aspartate, 0.6 part of trehalose, 0.05 part of xanthan gum, 1.0 parts of glycine betaine, methyl-prop two 6.0 parts of alcohol, 20.0 parts of 1% aqueous dispersion of Carbopol 941,0.16 part of triethanolamine, 0.8 part of parahydroxyacet-ophenone, 1,2 oneself two 0.8 part of alcohol, 6.0 parts of 1,3-BDO, 0.2 part of collagen protein powder, 0.15 part of 'alpha '-hydroxy acids.

Claims (4)

1. one kind is used to treat dermopathic medical dressing, it is characterised in that：It includes following components：EDTA-2Na, glycerine, thoroughly Bright matter acid sodium, oligomerization Sodium Hyaluronate, poly-aspartate, trehalose, xanthan gum, glycine betaine, methyl propanediol, carbomer, three Monoethanolamine, parahydroxyacet-ophenone, 1,2 hexylene glycol, 1,3-BDO, collagen protein powder, 'alpha '-hydroxy acids.
2. according to claim 1 be used to treat dermopathic medical dressing, it is characterised in that：The Sodium Hyaluronate is Middle numerator sodium hyaluronate.
3. according to claim 1 be used to treat dermopathic medical dressing, it is characterised in that：The carbomer is card ripple Nurse 941.
4. according to claim 1 be used to treat dermopathic medical dressing, it is characterised in that：It is wrapped in parts by mass Include following components：EDTA-2Na0.04 ~ 0.08 part, 2.0 ~ 6.0 parts of glycerine, middle 0.01 ~ 0.04 part of numerator sodium hyaluronate, oligomerization 0.02 ~ 0.06 part of Sodium Hyaluronate, 0.6 ~ 1.0 part of poly-aspartate, 0.2 ~ 0.6 part of trehalose, 0.01 ~ 0.05 part of xanthan gum, 0.6 ~ 1.0 part of glycine betaine, 2.0 ~ 6.0 parts of methyl propanediol, 10.0 ~ 20.0 parts of 1% aqueous dispersion of Carbopol 941, three ethanol 0.08 ~ 0.16 part of amine, 0.2 ~ 0.8 part of parahydroxyacet-ophenone, 1,2 0.2 ~ 0.8 part of hexylene glycol, 2.0 ~ 6.0 parts of 1,3-BDO, 0.08 ~ 0.2 part of collagen protein powder, 0.01 ~ 0.15 part of 'alpha '-hydroxy acids.
CN201710502327.2A 2017-06-27 2017-06-27 One kind is used to treat dermopathic medical dressing Withdrawn CN107376003A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710502327.2A CN107376003A (en) 2017-06-27 2017-06-27 One kind is used to treat dermopathic medical dressing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710502327.2A CN107376003A (en) 2017-06-27 2017-06-27 One kind is used to treat dermopathic medical dressing

Publications (1)

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CN107376003A true CN107376003A (en) 2017-11-24

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CN201710502327.2A Withdrawn CN107376003A (en) 2017-06-27 2017-06-27 One kind is used to treat dermopathic medical dressing

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CN (1) CN107376003A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110559475A (en) * 2019-09-19 2019-12-13 广州博民生物科技有限公司 Compound liquid dressing and preparation method thereof
CN113950317A (en) * 2019-05-27 2022-01-18 戴特姆生物技术公司 Collagen composition and use thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113950317A (en) * 2019-05-27 2022-01-18 戴特姆生物技术公司 Collagen composition and use thereof
CN110559475A (en) * 2019-09-19 2019-12-13 广州博民生物科技有限公司 Compound liquid dressing and preparation method thereof

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Application publication date: 20171124