CN107375788A - A kind of Chinese medicine composition and preparation method that can effectively treat psoriasis - Google Patents

A kind of Chinese medicine composition and preparation method that can effectively treat psoriasis Download PDF

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Publication number
CN107375788A
CN107375788A CN201710634152.0A CN201710634152A CN107375788A CN 107375788 A CN107375788 A CN 107375788A CN 201710634152 A CN201710634152 A CN 201710634152A CN 107375788 A CN107375788 A CN 107375788A
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chinese medicine
medicine composition
psoriasis
chinese
effectively treat
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孙思远
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Sichuan Yichuang Biotechnology Co Ltd
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Sichuan Yichuang Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/59Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/748Oldenlandia or Hedyotis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals

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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of Chinese medicine composition that can effectively treat psoriasis provided according to the understanding mechanism of Chinese traditional treatment psoriasis, each component and its mass parts ratio of the Chinese medicine composition are as follows:100~700g of smilax, 50~180g of radix scutellariae, 60~160g of the root bark of shaggy-fruited dittany, 60~160g of selfheal, 150~350g of oldenlandia diffusa, 30~90g of rhizoma menispermi, 40~120g of the radix paeoniae rubrathe, 30~120g of adder-wort, 80~160g of moutan bark, auxiliary material:Refined honey;Medicine provided by the invention is a good Chinese prescription.

Description

A kind of Chinese medicine composition and preparation method that can effectively treat psoriasis
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of Chinese medicine composition that can effectively treat psoriasis, especially It is the field of the Chinese medicine composition and preparation method used for psoriatic.
Background technology
Motherland's medical science thinks:Psoriasis, psoriasis are commonly called as psoriasis, are a kind of chronic inflammatory skins, and the course of disease is longer, There is easy tendency of recurrence, some cases almost cannot be cured all one's life.The disease is fallen ill based on person between twenty and fifty, to the health and spirit of patient Situation has a great influence.Clinical manifestation is with erythema, and based on the scales of skin that peel off, whole body can fall ill, and with scalp, it is relatively conventional that four limbs stretch side, more Aggravate in the winter time.
Clinical manifestation:
A. psoriasis vulgaris
For a most common type, more acute onsets.Typical performance is the erythema that boundary understands, shape size differs, and around has inflammation Property blush.Slightly infiltration thickens.Surface covers the multilayer silvery white scales of skin that peel off.The scales of skin that peel off be easy to scrape it is de-, it is light red shinny semi-transparent after scraping Bright film, scratch the visible small blutpunkte of film(Auspitz's sign).Skin lesion is apt to occur in head, sacrum portion and four limbs and stretches side.Suffer from part Person feels different degrees of itch.
B. psoriasis pustulosa
It is more rare, point general hair style and palm plantar type.Generalized pustular psoriasis are occur gregariousness superficial in erythema sterile Property warts, can partly be fused into purulence lake.Whole body can fall ill.Side is bent with four limbs and gauffer position is common, and mucous membrane of mouth can be simultaneously Involvement.Acute onset or be often accompanied by shivering with cold, generate heat when aggravating suddenly, arthralgia, general malaise and white blood cell count(WBC) increase Constitutional symptom.Is in periodical attack more, psoriasis vulgaris often occurs in the paracmasis.Palmoplantar pustulosis skin lesion is confined to Brothers, symmetrical to occur, general status is good, and the state of an illness is obstinate, recurrent exerbation
C. erythrodermic psoriasis
Also known as psoriatic exfoliative dermatitis, it is a kind of serious psoriasis.It is long-term a large amount of often because of the stronger medicine of external application excitant Using glucocorticoid, it is reduced caused by too fast or unexpected drug withdrawal.Show as whole skin and diffuse sexflush, swelling and furfur, companion There are the constitutional symptoms such as heating, chilly, discomfort, superficial lymph knot enlargement, white blood cell count(WBC) increases.
D. arthropathic psoriasis
Also known as psoriasis arthropathica.The joint damage of rheumatoid arthritis sample occurs simultaneously for psoriatic, can involve complete The big Minor articulus of body, but referred to end(Toe)Interphalangeal joints lesion most characteristic.Affected joints congestion and swelling pain, periarticular skin Also it is often red and swollen.Joint symptoms are often aggravated or mitigated simultaneously with skin symptom.Blood rheumatoid factor negative.
So, a kind of Chinese medicine composition for imitating treatment psoriasis how is just found, is that those skilled in the art urgently will Solve the problems, such as.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment psoriasis, people gradually appreciate Chinese traditional treatment The advantages of psoriasis, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment silver Consider the present situation of disease to be worth doing, the purpose of the present invention is to be to provide a kind of Chinese medicine composition that can effectively treat psoriasis, to solve silver bits The problem of patient gets well early.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and quality Part ratio, can effectively treat above-mentioned psoriasis.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is:Silver-colored bits can effectively be treated by providing one kind The Chinese medicine composition and preparation method of disease, it is characterised in that each component and its mass parts ratio of the Chinese medicine composition are as follows It is shown:
100~700g of smilax, 50~180g of radix scutellariae, 60~160g of the root bark of shaggy-fruited dittany, 60~160g of selfheal, oldenlandia diffusa 150 ~350g, 30~90g of rhizoma menispermi, 40~120g of the radix paeoniae rubrathe, 30~120g of adder-wort, 80~160g of moutan bark, auxiliary material:Refined honey(Often 110~155g refined honeys are added in 100g medicinal powder).
A kind of Chinese medicine composition and preparation method that can effectively treat psoriasis, it is characterised in that the Chinese medicine composition Each component and its mass parts than as follows:
115~600g of smilax, 58~150g of radix scutellariae, 70~140g of the root bark of shaggy-fruited dittany, 70~140g of selfheal, oldenlandia diffusa 180 ~310g, 38~80g of rhizoma menispermi, 48~105g of the radix paeoniae rubrathe, 36~105g of adder-wort, 90~140g of moutan bark, auxiliary material:Refined honey(Often 110~155g refined honeys are added in 100g medicinal powder).
A kind of Chinese medicine composition and preparation method that can effectively treat psoriasis, it is characterised in that " preferred plan " Chinese medicine composition each component and its mass parts than as follows:
Smilax 520g, radix scutellariae 130g, root bark of shaggy-fruited dittany 120g, selfheal 120g, oldenlandia diffusa 260g, rhizoma menispermi 70g, the radix paeoniae rubrathe 95g, adder-wort 95g, moutan bark 120g, auxiliary material:Refined honey(110~155g refined honeys are added in per 100g medicinal powder).
A kind of Chinese medicine composition and preparation method that can effectively treat psoriasis, it is characterised in that methods described is included such as Lower step is prepared:
A, in addition to refined honey, after above-mentioned raw materials Chinese medicine is picked impurity, dust and dried, it is ground into superfine end according to mass parts ratio and treats With;
B, the method for preparing Chinese medicine honey pill according to tradition, after ground superfine myrrh thing is crossed into 100 mesh sieves, it is well mixed, Produce medicinal powder 1.;It will be well mixed per addition 110~155g refined honeys in 100g medicinal powder, then prepare pelletization, produce honeyed bolus 2., 3. and then dry, sterilization, sealed packaging.
A kind of Chinese medicine composition and preparation method that can effectively treat psoriasis, it is characterised in that the instructions of taking is: By the honey pill agent medicine prepared twice a day to take, once a dose sooner or later, and dosage 9g/ times is before meals(Children, old man, Pregnant and lactant women uses with caution), while avoid eating beef, dog meats, wine, cured fish, sauce, peppery etc..30 days are a course for the treatment of, medication 2 ~6 courses for the treatment of, symptom gradually mitigate, and obtain temporary transient healing.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component:
Smilax, nature and flavor:It is sweet light, flat, there is the effect of removing damp-heat, let out turbid removing toxic substances, be easing joint movement, for treating syphilis, leaching The diseases such as turbid, diarrhea, muscles and bones contraction pain, tinea pedis, carbuncle swells, sore tinea, scrofula, goiter and tumor and mercury poisoning;
Radix scutellariae, nature and flavor:It is bitter, cold in nature, have clearing heat-fire, eliminating dampness removing toxic substances, hemostasis, it is antiabortive the effect of, for treating lung heat cough Cough, the headache of high fever apoplexy coma due to blocking of the respiratory system shies epilepsy, irascibility, red eye, swell pain, jaundice with damp-heat pathogen, rush down dysentery, heat gonorrhea, hematemesis blood, uterine bleeding, fetal movement with fever, carbuncle Swollen furunculosis;
The root bark of shaggy-fruited dittany, nature and flavor:It is bitter, salty, cold, there is the effect of heat-clearing and damp-drying drug, dispelling wind and arresting itching, removing toxic substances, for treating wind-heat wet poison institute The diseases such as the rubella of cause, eczema, mange, jaundice, damp-heat arthralgia;
Selfheal, nature and flavor:It is bitter, pungent, cold in nature, there is the effect of clearing liver and improving vision, powder detoxifcation, for treating mesh also photophobia, mesh Pearl pain, dizziness of having a headache, tinnitus, scrofula, goiter and tumor, acute mastitis, mumps, carbuncle furuncle poison, acute hepatitis, chronic hepatitis, high blood pressure;
Oldenlandia diffusa, nature and flavor:Bitter sweet, tremble with fear, be nontoxic, there is the effect of clearing heat and detoxicating, dampness removing, for treating dyspnea and cough due to lung-heat, pharynx The diseases such as larynx swelling and pain, acute appendicitis, furuncle sore, venomous snake bite, puckery pain of heat gonorrhea, oedema, dysentery, enteritis, jaundice with damp-heat pathogen, cancerous swelling;
Rhizoma menispermi, nature and flavor:It is bitter, cold, it is slightly poisonous, there is the effect of clearing heat and detoxicating, swelling and pain relieving, dampness removing, swollen for treating throat Bitterly, cough with lung heat, mumps, rush down dysentery, jaundice, arthralgia pain due to rheumatism, hemorrhoid gall, snake bite and insect sting;
The radix paeoniae rubrathe, nature and flavor:It is bitter, be slightly cold, there is the effect of clearing heat and cooling blood, promoting blood circulation, for treat febrile virulent maculae, hematemesis and epistaxis, Discharging fresh blood stool, red eye, swell pain, carbuncle swells sore, amenorrhoea, dysmenorrhoea, collapse band stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, hernia lump in the abdomen accumulation, injury from falling down;
Adder-wort, nature and flavor:Bitter, cold nature, mild toxicity, there is the effect of clearing heat and promoting diuresis, cooling blood and hemostasis, detoxicating and resolving a mass, for treating lung Heat cough, pyreticosis frightened epilepsy, dysentery characterized by blood in the stool, heat are rushed down, spitted blood, bleeding from five sense organs or subcutaneous tissue, hemorrhoid hemorrhage, carbuncle sore tumefacting virus;
Moutan bark, nature and flavor:It is arduous, cool, there is the effect of heat-clearing, cool blood and blood, dispersing blood stasis, for treat heat invading xuefen, hair spot, Frightened epilepsy, tell, be defeated in battle, having blood in stool, hectic fever due to yin labor heat, Amenorrhea, abdominal mass, large carbuncle, flutter damage etc. disease.
Medicine of the present invention is the principle based on Chinese traditional treatment psoriasis, from the pathomechanism according to psoriasis and pharmacological action Think:With regard to psoriasis, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good treatment to above-mentioned disease Effect.
Embodiment
A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned psoriasis, the medicine prepared using the formula Thing good drug efficacy, it is quick, it is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the tool of the present invention Body embodiment is described in further detail:
Embodiment 1:
A kind of Chinese medicine composition that can effectively treat psoriasis, it is characterised in that each component of the Chinese medicine composition and its Mass parts are than as follows:
Smilax 520g, radix scutellariae 130g, root bark of shaggy-fruited dittany 120g, selfheal 120g, oldenlandia diffusa 260g, rhizoma menispermi 70g, the radix paeoniae rubrathe 95g, adder-wort 95g, moutan bark 120g, auxiliary material:Refined honey(110~155g refined honeys are added in per 100g medicinal powder).
Embodiment 2:
A kind of Chinese medicine composition that can effectively treat psoriasis, it is characterised in that each component of the Chinese medicine composition and its Mass parts are than as follows:
Smilax 600g, radix scutellariae 150g, root bark of shaggy-fruited dittany 140g, selfheal 140g, oldenlandia diffusa 310g, rhizoma menispermi 80g, the radix paeoniae rubrathe 105g, adder-wort 105g, moutan bark 140g, auxiliary material:Refined honey(110~155g refined honeys are added in per 100g medicinal powder).
Embodiment 3:
A kind of Chinese medicine composition that can effectively treat psoriasis, it is characterised in that each component of the Chinese medicine composition and its Mass parts are than as follows:
Smilax 700g, radix scutellariae 180g, root bark of shaggy-fruited dittany 160g, selfheal 160g, oldenlandia diffusa 350g, rhizoma menispermi 90g, the radix paeoniae rubrathe 120g, adder-wort 120g, moutan bark 160g, auxiliary material:Refined honey(110~155g refined honeys are added in per 100g medicinal powder).
Model case
Through clinical conditions psoriatic totally 600, the age is 450 of more than 35 years old, only 150 for 35 years old with Under.Obtain 350 temporarily cured in 600 patients, effective 220, invalid 30.Total effective rate is up to 95%.

Claims (3)

  1. A kind of 1. Chinese medicine composition that can effectively treat psoriasis, it is characterised in that each component of the Chinese medicine composition and Its mass parts is than as follows:
    100~700g of smilax, 50~180g of radix scutellariae, 60~160g of the root bark of shaggy-fruited dittany, 60~160g of selfheal, oldenlandia diffusa 150 ~350g, 30~90g of rhizoma menispermi, 40~120g of the radix paeoniae rubrathe, 30~120g of adder-wort, 80~160g of moutan bark, auxiliary material:Refine close(Often 110~155g refined honeys are added in 100g medicinal powder).
  2. 2. the Chinese medicine composition according to claim 1 that can effectively treat psoriasis, it is characterised in that the Chinese traditional medicine composition The each component and its mass parts of thing are than as follows:
    115~600g of smilax, 58~150g of radix scutellariae, 70~140g of the root bark of shaggy-fruited dittany, 70~140g of selfheal, oldenlandia diffusa 180 ~310g, 38~80g of rhizoma menispermi, 48~105g of the radix paeoniae rubrathe, 36~105g of adder-wort, 90~140g of moutan bark, auxiliary material:Refine close(Often 110~155g refined honeys are added in 100g medicinal powder).
  3. 3. the Chinese medicine composition that can effectively treat psoriasis according to claim 1 to 2, it is characterised in that the Chinese medicine The each component and its mass parts of composition are than as follows:
    Smilax 520g, radix scutellariae 130g, root bark of shaggy-fruited dittany 120g, selfheal 120g, oldenlandia diffusa 260g, rhizoma menispermi 70g, the radix paeoniae rubrathe 95g, adder-wort 95g, moutan bark 120g, auxiliary material:Refine close(110~155g refined honeys are added in per 100g medicinal powder).
CN201710634152.0A 2017-07-29 2017-07-29 A kind of Chinese medicine composition and preparation method that can effectively treat psoriasis Withdrawn CN107375788A (en)

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